2II2A

Crystal structure of alpha-11 giardin
Total Genus 128
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
128
sequence length
304
structure length
304
Chain Sequence
YGDAIPEVKAILEAKNEEELVTFTSRWSAEERKELRTQFQDTTGLEFIAFLKKCIKNGPYEDVMALGWDCNISARVNVIKKAMKNVNDFRAIHDVVLIATPDERLKLAQAYKEKTGNDLLQDFVDQIPLTSAASYLCHLAIRENRTPRGSVASDAEVLKHNLIDADEPDHEAVVRLIITSTADEYKEINHRFEVLTGKSVQEAIETRYADKENARGLCIAHYYNLAPARAVAYAFHSAVETQNDDMAYEQAARITGLFHDLHKFAWVHYACWGVMRDDILSRFQSKEANKVNFRDACLMFWKLA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Alpha-11 giardin
publication title Apo and Calcium-bound Crystal Structures of Alpha-11 Giardin, an Unusual Annexin from Giardia lamblia
pubmed doi rcsb
source organism Giardia intestinalis
molecule tags Metal binding protein
total genus 128
structure length 304
sequence length 304
ec nomenclature
pdb deposition date 2006-09-27
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 2ii2A04
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 2ii2A01
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 2ii2A02
1.10.220.10 Mainly Alpha Orthogonal Bundle Annexin V; domain 1 Annexin 2ii2A03
3BRXA 1A8AA 1BC3A 2ZOCA 1AVRA 1ANXA 1BCWA 1MCXA 1M9IA 1BCZA 2HYUA 4HREA 4EVHA 1AXNA 1HM6A 1W3WA 1A8BA 2H0LA 1HVFA 4MDUA 1AOWA 2ZHJA 2RANA 1BC0A 1SAVA 1ALAA 1HAKA 1HVDA 1XJLA 2II2A 1W45A 1YJ0A 1N00A 1BCYA 1DM5A 1G5NA 1N42A 2XO3A 1ANNA 1HVEA 1YCNA 2IE6A 1AIIA 2IICA 4MDVA 1I4AA 1HVGA 1N41A 1W7BA 1YIIA 2H0KA 2HYVA 1AEIA 2ZHIA 1AVHA 4EVFA 2Q4CA 1BO9A 2HYWA 2H0MA 2IE7A 2XO2A 1ANWA 1BC1A 1AVCA 4X9PA 1DK5A 1N44A
chains in the Genus database with same CATH superfamily
1AVRA 1ANXA 4JMOA 3L8NA 1A8BA 1HVFA 4Z21A 1BC0A 1ALAA 4D7RA 1XSZA 1YGMA 1N42A 3ABSA 1ANNA 4FHRB 3ABOA 1YIIA 2R0DA 1XT0B 2ZHIA 4C0AA 3SWVA 4JWLA 1QC7A 2HYWA 2H0MA 4KN4X 1S9DE 1ANWA 3ANYA 1BC1A 4X9PA 1DK5A 1BC3A 1BCZA 2HYUA 4EVHA 3SOHB 2K6XA 3HJLA 1AOWA 1HAKA 1XJLA 1BCYA 1YCNA 2IE6A 4D7QA 1R4AE 1I4AA 1HVGA 1N41A 2H0KA 1LKVX 3LTLA 1AVHA 4JK1X 2IE7A 1R8SE 1G5NA 3TW5A 1A8AA 2ZOCA 1MCXA 1BCWA 1PBVA 1AXNA 1W3WA 2H0LA 1C1KA 1SAVA 2II2A 1W45A 1YJ0A 3USWA 3ABQA 1R8QE 1DM5A 2XO3A 1AIIA 4L5MA 4MDVA 2OY9A 2R09A 3USYA 1UPTB 1BC9A 1AEIA 4JXHA 1KU1A 1Q8DA 2Q4CA 1AVCA 1N44A 3BRXA 4FQ0C 3AJCA 1R8ME 1M9IA 4C7PA 2HSNA 4HREA 1HM6A 2VXGA 4MDUA 2ZHJA 2RANA 4Q2SA 3ABRA 1HVDA 4KN7X 1N00A 4OIYA 1HVEA 3AO0A 2IICA 1W7BA 1RE0B 4A4PA 2HYVA 4EVFA 1BO9A 2QEZA 2XO2A 4KMUX 4JMIA
chains in the Genus database with same CATH topology
3BRXA 1A8AA 1BC3A 2ZOCA 1AVRA 1ANXA 1BCWA 1MCXA 1M9IA 1BCZA 2HYUA 4HREA 4EVHA 1AXNA 1HM6A 1W3WA 1A8BA 2H0LA 1HVFA 4MDUA 1AOWA 2ZHJA 2RANA 1BC0A 1SAVA 1ALAA 1HAKA 1HVDA 1XJLA 2II2A 1W45A 1YJ0A 1N00A 1BCYA 1DM5A 1G5NA 1N42A 2XO3A 1ANNA 1HVEA 1YCNA 2IE6A 1AIIA 2IICA 4MDVA 1I4AA 1HVGA 1N41A 1W7BA 1YIIA 2H0KA 2HYVA 1AEIA 2ZHIA 1AVHA 4EVFA 2Q4CA 1BO9A 2HYWA 2H0MA 2IE7A 2XO2A 1ANWA 1BC1A 1AVCA 4X9PA 1DK5A 1N44A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BRX A;  1A8A A;  1BC3 A;  2ZOC A;  1AVR A;  1ANX A;  1BCW A;  1MCX A;  1M9I A;  1BCZ A;  2HYU A;  4HRE A;  4EVH A;  1AXN A;  1HM6 A;  1W3W A;  1A8B A;  2H0L A;  1HVF A;  4MDU A;  1AOW A;  2ZHJ A;  2RAN A;  1BC0 A;  1SAV A;  1ALA A;  1HAK A;  1HVD A;  1XJL A;  2II2 A;  1W45 A;  1YJ0 A;  1N00 A;  1BCY A;  1DM5 A;  1G5N A;  1N42 A;  2XO3 A;  1ANN A;  1HVE A;  1YCN A;  2IE6 A;  1AII A;  2IIC A;  4MDV A;  1I4A A;  1HVG A;  1N41 A;  1W7B A;  1YII A;  2H0K A;  2HYV A;  1AEI A;  2ZHI A;  1AVH A;  4EVF A;  2Q4C A;  1BO9 A;  2HYW A;  2H0M A;  2IE7 A;  2XO2 A;  1ANW A;  1BC1 A;  1AVC A;  4X9P A;  1DK5 A;  1N44 A; 
#chains in the Genus database with same CATH topology
 1AVR A;  1ANX A;  4JMO A;  3L8N A;  1A8B A;  1HVF A;  4Z21 A;  1BC0 A;  1ALA A;  4D7R A;  1XSZ A;  1YGM A;  1N42 A;  3ABS A;  1ANN A;  4FHR B;  3ABO A;  1YII A;  2R0D A;  1XT0 B;  2ZHI A;  4C0A A;  3SWV A;  4JWL A;  1QC7 A;  2HYW A;  2H0M A;  4KN4 X;  1S9D E;  1ANW A;  3ANY A;  1BC1 A;  4X9P A;  1DK5 A;  1BC3 A;  1BCZ A;  2HYU A;  4EVH A;  3SOH B;  2K6X A;  3HJL A;  1AOW A;  1HAK A;  1XJL A;  1BCY A;  1YCN A;  2IE6 A;  4D7Q A;  1R4A E;  1I4A A;  1HVG A;  1N41 A;  2H0K A;  1LKV X;  3LTL A;  1AVH A;  4JK1 X;  2IE7 A;  1R8S E;  1G5N A;  3TW5 A;  1A8A A;  2ZOC A;  1MCX A;  1BCW A;  1PBV A;  1AXN A;  1W3W A;  2H0L A;  1C1K A;  1SAV A;  2II2 A;  1W45 A;  1YJ0 A;  3USW A;  3ABQ A;  1R8Q E;  1DM5 A;  2XO3 A;  1AII A;  4L5M A;  4MDV A;  2OY9 A;  2R09 A;  3USY A;  1UPT B;  1BC9 A;  1AEI A;  4JXH A;  1KU1 A;  1Q8D A;  2Q4C A;  1AVC A;  1N44 A;  3BRX A;  4FQ0 C;  3AJC A;  1R8M E;  1M9I A;  4C7P A;  2HSN A;  4HRE A;  1HM6 A;  2VXG A;  4MDU A;  2ZHJ A;  2RAN A;  4Q2S A;  3ABR A;  1HVD A;  4KN7 X;  1N00 A;  4OIY A;  1HVE A;  3AO0 A;  2IIC A;  1W7B A;  1RE0 B;  4A4P A;  2HYV A;  4EVF A;  1BO9 A;  2QEZ A;  2XO2 A;  4KMU X;  4JMI A; 
#chains in the Genus database with same CATH homology
 3BRX A;  1A8A A;  1BC3 A;  2ZOC A;  1AVR A;  1ANX A;  1BCW A;  1MCX A;  1M9I A;  1BCZ A;  2HYU A;  4HRE A;  4EVH A;  1AXN A;  1HM6 A;  1W3W A;  1A8B A;  2H0L A;  1HVF A;  4MDU A;  1AOW A;  2ZHJ A;  2RAN A;  1BC0 A;  1SAV A;  1ALA A;  1HAK A;  1HVD A;  1XJL A;  2II2 A;  1W45 A;  1YJ0 A;  1N00 A;  1BCY A;  1DM5 A;  1G5N A;  1N42 A;  2XO3 A;  1ANN A;  1HVE A;  1YCN A;  2IE6 A;  1AII A;  2IIC A;  4MDV A;  1I4A A;  1HVG A;  1N41 A;  1W7B A;  1YII A;  2H0K A;  2HYV A;  1AEI A;  2ZHI A;  1AVH A;  4EVF A;  2Q4C A;  1BO9 A;  2HYW A;  2H0M A;  2IE7 A;  2XO2 A;  1ANW A;  1BC1 A;  1AVC A;  4X9P A;  1DK5 A;  1N44 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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