2IK8B

Crystal structure of the heterodimeric complex of human rgs16 and activated gi alpha 1
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
120
structure length
120
Chain Sequence
SFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEEFICSEAPKEVNIDHETRELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDLAAQA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Guanine nucleotide-binding protein G(i), alpha-1 subunit
total genus 42
structure length 120
sequence length 120
chains with identical sequence D
ec nomenclature
pdb deposition date 2006-10-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 2ik8B02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 2ik8B01
3PSCA 3PVWA 5HE1A 4PNKA 3KRWA 5DO9B 2CRPA 4EKDB 2OWIA 2BV1A 3NYOA 5HE0A 1FQIA 3CIKA 1EZTA 2IK8B 2JNUA 3NYNA 2D9JA 1FQJB 2V4ZB 5HE2A 3PVUA 4TNBA 3V5WA 2AF0A 2BCJA 2DLVA 2IHBB 2ODEB 3C7LA 2OJ4A 4TNDA 1EZYA 3C7KB 1FQKB 4MK0A 3KRXA 1EMUA 2GTPC 1CMZA 2JM5A 1AGRE 1OMWA 3UZTA 2IHDA 5HE3A 2BT2A 2EBZA 1DK8A
chains in the Genus database with same CATH superfamily
3PSCA 3PVWA 5HE1A 4PNKA 3KRWA 5DO9B 2CRPA 4EKDB 2OWIA 2BV1A 3NYOA 5HE0A 1FQIA 3CIKA 5REQB 1EZTA 2IK8B 2JNUA 3NYNA 2D9JA 3I5QA 1FQJB 2V4ZB 5HE2A 3PVUA 4TNBA 3V5WA 2AF0A 2BCJA 2DLVA 2IHBB 2ODEB 3C7LA 2OJ4A 4HTEA 4TNDA 3C7KB 1EZYA 1FQKB 4MK0A 3KRXA 1EMUA 2GTPC 1CMZA 3QYFA 2JM5A 1AGRE 1OMWA 3UZTA 2IHDA 5HE3A 2BT2A 2EBZA 1DK8A
chains in the Genus database with same CATH topology
3PSCA 3PVWA 5HE1A 4PNKA 3KRWA 5DO9B 2CRPA 4EKDB 2OWIA 2BV1A 3NYOA 5HE0A 1FQIA 3CIKA 5REQB 1EZTA 2IK8B 2JNUA 3NYNA 2D9JA 1FQJB 2V4ZB 5HE2A 3PVUA 4TNBA 3V5WA 2AF0A 2BCJA 2DLVA 2IHBB 2ODEB 3C7LA 2OJ4A 4TNDA 1EZYA 3C7KB 1FQKB 4MK0A 3KRXA 1EMUA 2GTPC 1CMZA 3QYFA 2JM5A 1AGRE 1OMWA 3UZTA 2IHDA 5HE3A 2BT2A 2EBZA 1DK8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PSC A;  3PVW A;  5HE1 A;  4PNK A;  3KRW A;  5DO9 B;  2CRP A;  4EKD B;  2OWI A;  2BV1 A;  3NYO A;  5HE0 A;  1FQI A;  3CIK A;  1EZT A;  2IK8 B;  2JNU A;  3NYN A;  2D9J A;  1FQJ B;  2V4Z B;  5HE2 A;  3PVU A;  4TNB A;  3V5W A;  2AF0 A;  2BCJ A;  2DLV A;  2IHB B;  2ODE B;  3C7L A;  2OJ4 A;  4TND A;  1EZY A;  3C7K B;  1FQK B;  4MK0 A;  3KRX A;  1EMU A;  2GTP C;  1CMZ A;  2JM5 A;  1AGR E;  1OMW A;  3UZT A;  2IHD A;  5HE3 A;  2BT2 A;  2EBZ A;  1DK8 A; 
#chains in the Genus database with same CATH topology
 3PSC A;  3PVW A;  5HE1 A;  4PNK A;  3KRW A;  5DO9 B;  2CRP A;  4EKD B;  2OWI A;  2BV1 A;  3NYO A;  5HE0 A;  1FQI A;  3CIK A;  5REQ B;  1EZT A;  2IK8 B;  2JNU A;  3NYN A;  2D9J A;  3I5Q A;  1FQJ B;  2V4Z B;  5HE2 A;  3PVU A;  4TNB A;  3V5W A;  2AF0 A;  2BCJ A;  2DLV A;  2IHB B;  2ODE B;  3C7L A;  2OJ4 A;  4HTE A;  4TND A;  3C7K B;  1EZY A;  1FQK B;  4MK0 A;  3KRX A;  1EMU A;  2GTP C;  1CMZ A;  3QYF A;  2JM5 A;  1AGR E;  1OMW A;  3UZT A;  2IHD A;  5HE3 A;  2BT2 A;  2EBZ A;  1DK8 A; 
#chains in the Genus database with same CATH homology
 3PSC A;  3PVW A;  5HE1 A;  4PNK A;  3KRW A;  5DO9 B;  2CRP A;  4EKD B;  2OWI A;  2BV1 A;  3NYO A;  5HE0 A;  1FQI A;  3CIK A;  5REQ B;  1EZT A;  2IK8 B;  2JNU A;  3NYN A;  2D9J A;  1FQJ B;  2V4Z B;  5HE2 A;  3PVU A;  4TNB A;  3V5W A;  2AF0 A;  2BCJ A;  2DLV A;  2IHB B;  2ODE B;  3C7L A;  2OJ4 A;  4TND A;  1EZY A;  3C7K B;  1FQK B;  4MK0 A;  3KRX A;  1EMU A;  2GTP C;  1CMZ A;  3QYF A;  2JM5 A;  1AGR E;  1OMW A;  3UZT A;  2IHD A;  5HE3 A;  2BT2 A;  2EBZ A;  1DK8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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