2IMGA

Crystal structure of dual specificity protein phosphatase 23 from homo sapiens in complex with ligand malate ion
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
149
structure length
149
Chain Sequence
GVQPPNFSWVLPGRLAGLALPRLPAHYQFLLDLGVRHLVSLTERGPPHSDSCPGLTLHRLRIPDFCPPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQFYQRTK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of human dual specificity protein phosphatase 23, VHZ, enzyme-substrate/product complex.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Dual specificity protein phosphatase 23
total genus 51
structure length 149
sequence length 149
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2006-10-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00782 DSPc Dual specificity phosphatase, catalytic domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2imgA00
1PTUA 3QCHA 1PH0A 4OHEA 3V0EA 3F9AA 1C88A 1Q6TA 1A5YA 3A5JA 4OHDA 3D1HA 3V0FA 5K9VA 1G4WR 2H03A 2OOQA 3F81A 2B49A 4H1OA 4QBWA 1RXDA 5K23A 1Q6JA 4D3QA 2CNEA 5BX1A 1OEVA 2I6IA 5BZZA 3S3HA 3ZM3A 2HC2A 1BZCA 3O3LA 3QCLA 3EB1A 4RH9A 2F46A 4BPCA 2HNPA 1U24A 1XM2A 4PVGA 1I9TA 2B07A 1C85A 2M3VA 2MBCA 2BV5A 3QCBA 2QBPA 5EHPA 3QCIA 1C84A 2B4OA 1ECVA 2CFVA 3D1OA 3QCDA 4NWFA 2I3UA 1PTVA 3RZ2A 1G7FA 4GE5A 2ESBA 2H04A 2H4GA 1OEOX 2IMGA 1Q1MA 4ZN5A 2C46A 3PS5A 1NO6A 1NNYA 1XRIA 4R30A 3I80A 3GXHA 4S0GA 5KABA 5K22A 3EU0A 3U96A 1PTTA 2PSZA 3RGOA 1T4JA 2QEPA 4JMJA 2AHSA 2CMBA 2HCMA 2QCJA 2FH7A 2QBSA 2NT2A 2E0TA 4WU3A 1FPZA 4IKCA 3S4OA 1KAVA 2AZRA 3MOZA 2F6YA 1PTYA 4HJPA 2G59A 1YPTA 2I4HA 3QCKA 1ONZA 3QCJA 3BLUA 5K24A 2F6TA 5KADA 1L8KA 2I42A 2P4DA 1PA9A 2NV5A 4RHGA 2VEXA 4HJQA 3D1QA 2F6WA 4Z6BA 4JMKA 2Y96A 2CM8A 1U25A 5KA1A 2B4PA 4GRZA 4GE2A 2H02A 4GWFA 1OESA 1Q6SA 1GFYA 1YGRA 2OUDA 5KA7A 1XXPA 4RKKA 2Q05A 2F6FA 1KAKA 4H34A 3AWFA 2F6ZA 4DGXA 5EHRA 3BLTA 3I36A 3S3EA 4QUNA 2HNQA 1LQFA 4RI4A 3D44A 1M3GA 1G4US 3LJ8A 2NZ6A 3QKQA 3CWEA 1ZZWA 2F71A 2BGDA 4Y14A 5BUGA 3ZM2A 3O4UA 3V0HA 3QCMA 5GTJA 1I9SA 3RGQA 1NWEA 1YN9A 2NLKA 1I57A 1G1GA 1Q6PA 2I6OA 4RDDA 2CM7A 4QBEA 5KA2A 2PBNA 3OLRA 3QCEA 4R0SA 1C86A 4MBBA 1ZCKA 1XXVA 4JNBA 1YTSA 3EMUA 3ZM0A 2A3KA 4ZRTA 1YFOA 2I3RA 2QBRA 4D3RA 4J51A 3EZZA 1EENA 2HB1A 3QCCA 4KYQA 1LYVA 1JF7A 1OHEA 3MOWA 2F6VA 2ZMMA 4Y2EA 5KA3A 2HVLA 3O4TA 4TVVA 1V3AA 2A8BA 2PT0A 3D42A 3CM3A 2CNHA 1BZHA 1EEOA 1T49A 1NL9A 4WTYA 4GFUA 3AWEA 4OHHA 2CM3A 1YTNA 2H4KA 2PQ5A 5KA9A 2ZN7A 3QCFA 1OHDA 3F41A 2OC3A 2G6ZA 4GRYA 4QAHA 4AZ1A 2J16B 2VEWA 2QBQA 5LXQB 1YGUA 1GWZA 4R0TA 3S3KA 3ZMPA 1QZ0A 2FJNA 4D3PA 2B4SA 2CMAA 3M4UA 4ERCA 4HRFA 3S3FA 4DGPA 5K9WA 2I4GA 3NMEA 5HDEA 4WOHA 2J17A 4NNDA 1NWLA 1ZC0A 3EAXA 5I6VA 2VEYA 2QDMA 2Y2FA 1PXHA 1C87A 4QAPA 5KA4A 1X24A 2BZLA 3GXGA 2NT7A 1MKPA 3AWGA 2PA5A 2OZ5A 5AWXA 3V0DA 5KAAA 4RH5A 3QKPA 3QCNA 2RF6A 2GP0A 2HXPA 3BM8A 4RI5A 2CM2A 3N0AA 3V0GA 3I7ZA 5IBMA 4OHLA 4I8NA 3D9CA 1Q6MA 4NX8A 2B4UA 1C83A 1LARA 1NZ7A 2YDUA 2SHPA 5IBSA 1BZJA 1L8GA 2F70A 2FJMA 2DXPA 3QCGA 1YTWA 3ZV2A 1OEMX 1YWFA 5KA8A 2NTAA 4NYHA 2I1YA 2I6MA 1PA1A 4NWGA 4B04A 1OHCA 1XBOA 2I4EA 3SMEA 3MMJA 2CNIA 2P6XA 4ZI4A 2GJTA 2Q47A 5KA0A 2BGEA 3H2XA 2WGPA 3B7OA 3RO1A 1FQ1A 1G7GA 2CJZA 1JLNA 1YZ4A 1AAXA 2I6PA 2H4VA 4KI9A 5KACA 4JBCA 3O4SA 2B3OA 4GE6A 1J4XA 3SR9A 2PI7A 2I5XA 4PYHA 5BZXA 1WRMA 4YR8B 5MMZB 4OHIA 4WU2A 2C7SA 5M43A 2CNFA 3F99A 1OETA 2QCTA 2QDCA 1ZCLA 3S4EA 1T48A 2CMCA 4KYRA 3V0IA 2JJDA 1PYNA 1G1HA 1FPRA 1VHRA 1ONYA 4BJOA 1OEUA 2R0BA 2I6JA 2BIJA 1SUGA 1D5RA 1WCHA 1R6HA 2VEUA 3ZMQA 3V0JA 2HC1A 1U26A 5K25A 1P15A 3OMHA 2CNGA 1WAXA 5J8RA 3O5XA 3BRHA 2GWOA 4QUMA 1RPMA 4ICZA 2QDPA 4YAAA 3A5KA 4GFVA 2VEVA 2J16A 3ZM1A 2HY3A 1Q6NA 2I75A 1QXKA 4GS0A 3F9BA 1G1FA
chains in the Genus database with same CATH superfamily
1PTUA 3QCHA 1PH0A 4OHEA 3V0EA 3F9AA 1C88A 1Q6TA 1A5YA 3A5JA 4OHDA 3D1HA 3V0FA 5K9VA 3MVNA 1G4WR 2H03A 2OOQA 3F81A 2B49A 4H1OA 4QBWA 1RXDA 5K23A 1Q6JA 3N2AA 2CNEA 4D3QA 5BX1A 1OEVA 2I6IA 5BZZA 1JBVA 3S3HA 3ZM3A 2HC2A 1J6UA 1BZCA 3O3LA 3QCLA 3EB1A 4RH9A 2F46A 4BPCA 2HNPA 1JBWA 1U24A 1XM2A 2VTDA 4PVGA 1I9TA 2B07A 1C85A 2M3VA 2F00A 2MBCA 2BV5A 3QCBA 2QBPA 5EHPA 3QCIA 1GG4A 1C84A 2B4OA 1ECVA 2CFVA 3D1OA 3QCDA 4UAGA 4NWFA 2I3UA 1PTVA 3RZ2A 1P31A 1G7FA 4GE5A 2ESBA 2H04A 2H4GA 1OEOX 2IMGA 1Q1MA 4ZN5A 2C46A 1E8CA 3PS5A 1NO6A 1NNYA 1XRIA 4R30A 2WJPA 3I80A 4CVLA 3GXHA 4S0GA 5KABA 5K22A 3EU0A 3U96A 1PTTA 2PSZA 5A5EA 3RGOA 1T4JA 2QEPA 4JMJA 2AHSA 2CMBA 2HCMA 2QCJA 2FH7A 1P3DA 2QBSA 2NT2A 1GQQA 2E0TA 4WU3A 1FPZA 4IKCA 3S4OA 1KAVA 2AZRA 3MOZA 4HV4A 2F6YA 1PTYA 4HJPA 2G59A 1YPTA 2I4HA 3QCKA 2Y67A 1ONZA 3QCJA 3BLUA 5K24A 2F6TA 5KADA 1L8KA 2I42A 2P4DA 3ZL8A 1PA9A 4CVKA 2NV5A 3HN7A 4RHGA 2VEXA 4HJQA 3D1QA 4C13A 4BUCA 2F6WA 4Z6BA 4JMKA 2Y96A 2Y66A 2X5OA 2CM8A 1U25A 5KA1A 2B4PA 4GRZA 4GE2A 2GC6A 3ZM6A 2H02A 4GWFA 1OESA 1Q6SA 1GFYA 1YGRA 2OUDA 5KA7A 1XXPA 4RKKA 2Q05A 2F6FA 1KAKA 4H34A 3AWFA 2F6ZA 4DGXA 5EHRA 3BLTA 3I36A 3PYZA 3S3EA 4QUNA 2HNQA 1LQFA 4RI4A 3D44A 1M3GA 1G4US 3LJ8A 2NZ6A 3QKQA 3CWEA 1ZZWA 2F71A 2BGDA 4Y14A 5BUGA 3ZM2A 3O4UA 3V0HA 3QCMA 5GTJA 1I9SA 3RGQA 1NWEA 1YN9A 2UUPA 2NLKA 1I57A 1G1GA 3UAGA 1Q6PA 2I6OA 4RDDA 2CM7A 4QBEA 5KA2A 2PBNA 3OLRA 3QCEA 4R0SA 2UAGA 2Y68A 1C86A 4MBBA 1ZCKA 1XXVA 2VORA 1EEHA 4JNBA 1YTSA 3EMUA 1W7KA 3ZM0A 2A3KA 4ZRTA 1YFOA 2I3RA 2QBRA 2Y1OA 4D3RA 4J51A 3EZZA 1EENA 3QCZA 2HB1A 3QCCA 4KYQA 1LYVA 1JF7A 2GCBA 1OHEA 3MOWA 1O5ZA 2F6VA 2ZMMA 4Y2EA 5KA3A 2HVLA 3O4TA 4TVVA 1E0DA 1V3AA 2A8BA 2PT0A 3D42A 3CM3A 2CNHA 1BZHA 1EEOA 1T49A 1NL9A 4WTYA 4GFUA 3ZM5A 3AWEA 4OHHA 2CM3A 2WTZA 1YTNA 2H4KA 2PQ5A 5KA9A 2ZN7A 3QCFA 1OHDA 3F41A 2OC3A 2G6ZA 4GRYA 4QAHA 2JFHA 4AZ1A 2J16B 2VEWA 2QBQA 5LXQB 1YGUA 1GWZA 4R0TA 3S3KA 3ZMPA 1QZ0A 2FJNA 3NRSA 4D3PA 2B4SA 2CMAA 3M4UA 4ERCA 4HRFA 3S3FA 4DGPA 5K9WA 2I4GA 3NMEA 5HDEA 4WOHA 2J17A 4NNDA 1NWLA 1ZC0A 3EAXA 5I6VA 2VEYA 2QDMA 2Y2FA 1PXHA 1C87A 4QAPA 1UAGA 1GQYA 5KA4A 1X24A 2BZLA 3GXGA 2NT7A 1MKPA 3AWGA 2PA5A 2OZ5A 5AWXA 3V0DA 5KAAA 4RH5A 3QKPA 3QCNA 2RF6A 2GP0A 2HXPA 3BM8A 4RI5A 2CM2A 3N0AA 3V0GA 1FGSA 3I7ZA 5IBMA 4OHLA 4I8NA 3D9CA 1Q6MA 4NX8A 2B4UA 1C83A 1LARA 1NZ7A 2YDUA 2SHPA 5IBSA 1BZJA 1L8GA 2F70A 2FJMA 2DXPA 3QCGA 1YTWA 2GC5A 2JFFA 3ZV2A 1OEMX 1YWFA 5KA8A 2NTAA 4NYHA 4C12A 4ZIYA 2I1YA 2I6MA 1PA1A 4NWGA 4B04A 1OHCA 1XBOA 2I4EA 5A5FA 3SMEA 3MMJA 2CNIA 2P6XA 4ZI4A 2GJTA 2Q47A 5KA0A 2BGEA 3H2XA 2WGPA 3B7OA 3RO1A 1FQ1A 1G7GA 2CJZA 1JLNA 1YZ4A 1AAXA 2I6PA 2GCAA 2H4VA 4KI9A 5KACA 4JBCA 3O4SA 2B3OA 4GE6A 1J4XA 3SR9A 2PI7A 2I5XA 4PYHA 5BZXA 4BUBA 1WRMA 4YR8B 5MMZB 4OHIA 4WU2A 2C7SA 5M43A 2CNFA 3F99A 1OETA 2QCTA 2QDCA 1ZCLA 2XJAA 4QF5A 3S4EA 1T48A 2CMCA 2VTEA 4KYRA 3V0IA 2JJDA 1PYNA 1G1HA 1FPRA 2JFGA 1VHRA 4CVMA 1ONYA 4BJOA 1OEUA 2R0BA 2AM2A 2I6JA 2BIJA 1SUGA 1D5RA 1WCHA 1R6HA 2VEUA 3ZMQA 3V0JA 2UUOA 2HC1A 1U26A 5K25A 1P15A 3OMHA 2CNGA 1WAXA 5J8RA 3LK7A 3O5XA 2XPCA 3BRHA 2GWOA 4QUMA 2VOSA 1RPMA 4ICZA 2QDPA 4QDIA 4YAAA 3A5KA 4GFVA 2VEVA 2J16A 3ZM1A 2HY3A 1Q6NA 2I75A 2AM1A 1QXKA 4GS0A 3F9BA 1G1FA 1W78A
chains in the Genus database with same CATH topology
1PTUA 3QCHA 1PH0A 4OHEA 3V0EA 3F9AA 1C88A 1Q6TA 1A5YA 3A5JA 4OHDA 3D1HA 3V0FA 5K9VA 1G4WR 2H03A 2OOQA 3F81A 2B49A 4H1OA 4QBWA 1RXDA 5K23A 1Q6JA 4D3QA 2CNEA 5BX1A 1OEVA 2I6IA 5BZZA 3S3HA 3ZM3A 2HC2A 1BZCA 3O3LA 3QCLA 3EB1A 4RH9A 2F46A 4BPCA 2HNPA 1U24A 1XM2A 4PVGA 1I9TA 2B07A 1C85A 2M3VA 2MBCA 2BV5A 3QCBA 2QBPA 5EHPA 3QCIA 1C84A 2B4OA 1ECVA 2CFVA 3D1OA 3QCDA 4NWFA 2I3UA 1PTVA 3RZ2A 1G7FA 4GE5A 2ESBA 2H04A 2H4GA 1OEOX 2IMGA 1Q1MA 4ZN5A 2C46A 3PS5A 1NO6A 1NNYA 1XRIA 4R30A 3I80A 3GXHA 4S0GA 5KABA 5K22A 3EU0A 3U96A 1PTTA 2PSZA 3RGOA 1T4JA 2QEPA 4JMJA 2AHSA 2CMBA 2HCMA 2QCJA 2FH7A 2QBSA 2NT2A 2E0TA 4WU3A 1FPZA 4IKCA 3S4OA 1KAVA 2AZRA 3MOZA 2F6YA 1PTYA 4HJPA 2G59A 1YPTA 2I4HA 3QCKA 1ONZA 3QCJA 3BLUA 5K24A 2F6TA 5KADA 1L8KA 2I42A 2P4DA 1PA9A 2NV5A 4RHGA 2VEXA 4HJQA 3D1QA 2F6WA 4Z6BA 4JMKA 2Y96A 2CM8A 1U25A 5KA1A 2B4PA 4GRZA 4GE2A 2H02A 4GWFA 1OESA 1Q6SA 1GFYA 1YGRA 2OUDA 5KA7A 1XXPA 4RKKA 2Q05A 2F6FA 1KAKA 4H34A 3AWFA 2F6ZA 4DGXA 5EHRA 3BLTA 3I36A 3S3EA 4QUNA 2HNQA 1LQFA 4RI4A 3D44A 1M3GA 1G4US 3LJ8A 2NZ6A 3QKQA 3CWEA 1ZZWA 2F71A 2BGDA 4Y14A 5BUGA 3ZM2A 3O4UA 3V0HA 3QCMA 5GTJA 1I9SA 3RGQA 1NWEA 1YN9A 2NLKA 1I57A 1G1GA 1Q6PA 2I6OA 4RDDA 2CM7A 4QBEA 5KA2A 2PBNA 3OLRA 3QCEA 4R0SA 1C86A 4MBBA 1ZCKA 1XXVA 4JNBA 1YTSA 3EMUA 3ZM0A 2A3KA 4ZRTA 1YFOA 2I3RA 2QBRA 4D3RA 4J51A 3EZZA 1EENA 2HB1A 3QCCA 4KYQA 1LYVA 1JF7A 1OHEA 3MOWA 2F6VA 2ZMMA 4Y2EA 5KA3A 2HVLA 3O4TA 4TVVA 1V3AA 2A8BA 2PT0A 3D42A 3CM3A 2CNHA 1BZHA 1EEOA 1T49A 1NL9A 4WTYA 4GFUA 3AWEA 4OHHA 2CM3A 1YTNA 2H4KA 2PQ5A 5KA9A 2ZN7A 3QCFA 1OHDA 3F41A 2OC3A 2G6ZA 4GRYA 4QAHA 4AZ1A 2J16B 2VEWA 2QBQA 5LXQB 1YGUA 1GWZA 4R0TA 3S3KA 3ZMPA 1QZ0A 2FJNA 4D3PA 2B4SA 2CMAA 3M4UA 4ERCA 4HRFA 3S3FA 4DGPA 5K9WA 2I4GA 3NMEA 5HDEA 4WOHA 2J17A 4NNDA 1NWLA 1ZC0A 3EAXA 5I6VA 2VEYA 2QDMA 2Y2FA 1PXHA 1C87A 4QAPA 5KA4A 1X24A 2BZLA 3GXGA 2NT7A 1MKPA 3AWGA 2PA5A 2OZ5A 5AWXA 3V0DA 5KAAA 4RH5A 3QKPA 3QCNA 2RF6A 2GP0A 2HXPA 3BM8A 4RI5A 2CM2A 3N0AA 3V0GA 3I7ZA 5IBMA 4OHLA 4I8NA 3D9CA 1Q6MA 4NX8A 2B4UA 1C83A 1LARA 1NZ7A 2YDUA 2SHPA 5IBSA 1BZJA 1L8GA 2F70A 2FJMA 2DXPA 3QCGA 1YTWA 3ZV2A 1OEMX 1YWFA 5KA8A 2NTAA 4NYHA 2I1YA 2I6MA 1PA1A 4NWGA 4B04A 1OHCA 1XBOA 2I4EA 3SMEA 3MMJA 2CNIA 2P6XA 4ZI4A 2GJTA 2Q47A 5KA0A 2BGEA 3H2XA 2WGPA 3B7OA 3RO1A 1FQ1A 1G7GA 2CJZA 1JLNA 1YZ4A 1AAXA 2I6PA 2H4VA 4KI9A 5KACA 4JBCA 3O4SA 2B3OA 4GE6A 1J4XA 3SR9A 2PI7A 2I5XA 4PYHA 5BZXA 1WRMA 4YR8B 5MMZB 4OHIA 4WU2A 2C7SA 5M43A 2CNFA 3F99A 1OETA 2QCTA 2QDCA 1ZCLA 3S4EA 1T48A 2CMCA 4KYRA 3V0IA 2JJDA 1PYNA 1G1HA 1FPRA 1VHRA 1ONYA 4BJOA 1OEUA 2R0BA 2I6JA 2BIJA 1SUGA 1D5RA 1WCHA 1R6HA 2VEUA 3ZMQA 3V0JA 2HC1A 1U26A 5K25A 1P15A 3OMHA 2CNGA 1WAXA 5J8RA 3O5XA 3BRHA 2GWOA 4QUMA 1RPMA 4ICZA 2QDPA 4YAAA 3A5KA 4GFVA 2VEVA 2J16A 3ZM1A 2HY3A 1Q6NA 2I75A 1QXKA 4GS0A 3F9BA 1G1FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PTU A;  3QCH A;  1PH0 A;  4OHE A;  3V0E A;  3F9A A;  1C88 A;  1Q6T A;  1A5Y A;  3A5J A;  4OHD A;  3D1H A;  3V0F A;  5K9V A;  1G4W R;  2H03 A;  2OOQ A;  3F81 A;  2B49 A;  4H1O A;  4QBW A;  1RXD A;  5K23 A;  1Q6J A;  4D3Q A;  2CNE A;  5BX1 A;  1OEV A;  2I6I A;  5BZZ A;  3S3H A;  3ZM3 A;  2HC2 A;  1BZC A;  3O3L A;  3QCL A;  3EB1 A;  4RH9 A;  2F46 A;  4BPC A;  2HNP A;  1U24 A;  1XM2 A;  4PVG A;  1I9T A;  2B07 A;  1C85 A;  2M3V A;  2MBC A;  2BV5 A;  3QCB A;  2QBP A;  5EHP A;  3QCI A;  1C84 A;  2B4O A;  1ECV A;  2CFV A;  3D1O A;  3QCD A;  4NWF A;  2I3U A;  1PTV A;  3RZ2 A;  1G7F A;  4GE5 A;  2ESB A;  2H04 A;  2H4G A;  1OEO X;  2IMG A;  1Q1M A;  4ZN5 A;  2C46 A;  3PS5 A;  1NO6 A;  1NNY A;  1XRI A;  4R30 A;  3I80 A;  3GXH A;  4S0G A;  5KAB A;  5K22 A;  3EU0 A;  3U96 A;  1PTT A;  2PSZ A;  3RGO A;  1T4J A;  2QEP A;  4JMJ A;  2AHS A;  2CMB A;  2HCM A;  2QCJ A;  2FH7 A;  2QBS A;  2NT2 A;  2E0T A;  4WU3 A;  1FPZ A;  4IKC A;  3S4O A;  1KAV A;  2AZR A;  3MOZ A;  2F6Y A;  1PTY A;  4HJP A;  2G59 A;  1YPT A;  2I4H A;  3QCK A;  1ONZ A;  3QCJ A;  3BLU A;  5K24 A;  2F6T A;  5KAD A;  1L8K A;  2I42 A;  2P4D A;  1PA9 A;  2NV5 A;  4RHG A;  2VEX A;  4HJQ A;  3D1Q A;  2F6W A;  4Z6B A;  4JMK A;  2Y96 A;  2CM8 A;  1U25 A;  5KA1 A;  2B4P A;  4GRZ A;  4GE2 A;  2H02 A;  4GWF A;  1OES A;  1Q6S A;  1GFY A;  1YGR A;  2OUD A;  5KA7 A;  1XXP A;  4RKK A;  2Q05 A;  2F6F A;  1KAK A;  4H34 A;  3AWF A;  2F6Z A;  4DGX A;  5EHR A;  3BLT A;  3I36 A;  3S3E A;  4QUN A;  2HNQ A;  1LQF A;  4RI4 A;  3D44 A;  1M3G A;  1G4U S;  3LJ8 A;  2NZ6 A;  3QKQ A;  3CWE A;  1ZZW A;  2F71 A;  2BGD A;  4Y14 A;  5BUG A;  3ZM2 A;  3O4U A;  3V0H A;  3QCM A;  5GTJ A;  1I9S A;  3RGQ A;  1NWE A;  1YN9 A;  2NLK A;  1I57 A;  1G1G A;  1Q6P A;  2I6O A;  4RDD A;  2CM7 A;  4QBE A;  5KA2 A;  2PBN A;  3OLR A;  3QCE A;  4R0S A;  1C86 A;  4MBB A;  1ZCK A;  1XXV A;  4JNB A;  1YTS A;  3EMU A;  3ZM0 A;  2A3K A;  4ZRT A;  1YFO A;  2I3R A;  2QBR A;  4D3R A;  4J51 A;  3EZZ A;  1EEN A;  2HB1 A;  3QCC A;  4KYQ A;  1LYV A;  1JF7 A;  1OHE A;  3MOW A;  2F6V A;  2ZMM A;  4Y2E A;  5KA3 A;  2HVL A;  3O4T A;  4TVV A;  1V3A A;  2A8B A;  2PT0 A;  3D42 A;  3CM3 A;  2CNH A;  1BZH A;  1EEO A;  1T49 A;  1NL9 A;  4WTY A;  4GFU A;  3AWE A;  4OHH A;  2CM3 A;  1YTN A;  2H4K A;  2PQ5 A;  5KA9 A;  2ZN7 A;  3QCF A;  1OHD A;  3F41 A;  2OC3 A;  2G6Z A;  4GRY A;  4QAH A;  4AZ1 A;  2J16 B;  2VEW A;  2QBQ A;  5LXQ B;  1YGU A;  1GWZ A;  4R0T A;  3S3K A;  3ZMP A;  1QZ0 A;  2FJN A;  4D3P A;  2B4S A;  2CMA A;  3M4U A;  4ERC A;  4HRF A;  3S3F A;  4DGP A;  5K9W A;  2I4G A;  3NME A;  5HDE A;  4WOH A;  2J17 A;  4NND A;  1NWL A;  1ZC0 A;  3EAX A;  5I6V A;  2VEY A;  2QDM A;  2Y2F A;  1PXH A;  1C87 A;  4QAP A;  5KA4 A;  1X24 A;  2BZL A;  3GXG A;  2NT7 A;  1MKP A;  3AWG A;  2PA5 A;  2OZ5 A;  5AWX A;  3V0D A;  5KAA A;  4RH5 A;  3QKP A;  3QCN A;  2RF6 A;  2GP0 A;  2HXP A;  3BM8 A;  4RI5 A;  2CM2 A;  3N0A A;  3V0G A;  3I7Z A;  5IBM A;  4OHL A;  4I8N A;  3D9C A;  1Q6M A;  4NX8 A;  2B4U A;  1C83 A;  1LAR A;  1NZ7 A;  2YDU A;  2SHP A;  5IBS A;  1BZJ A;  1L8G A;  2F70 A;  2FJM A;  2DXP A;  3QCG A;  1YTW A;  3ZV2 A;  1OEM X;  1YWF A;  5KA8 A;  2NTA A;  4NYH A;  2I1Y A;  2I6M A;  1PA1 A;  4NWG A;  4B04 A;  1OHC A;  1XBO A;  2I4E A;  3SME A;  3MMJ A;  2CNI A;  2P6X A;  4ZI4 A;  2GJT A;  2Q47 A;  5KA0 A;  2BGE A;  3H2X A;  2WGP A;  3B7O A;  3RO1 A;  1FQ1 A;  1G7G A;  2CJZ A;  1JLN A;  1YZ4 A;  1AAX A;  2I6P A;  2H4V A;  4KI9 A;  5KAC A;  4JBC A;  3O4S A;  2B3O A;  4GE6 A;  1J4X A;  3SR9 A;  2PI7 A;  2I5X A;  4PYH A;  5BZX A;  1WRM A;  4YR8 B;  5MMZ B;  4OHI A;  4WU2 A;  2C7S A;  5M43 A;  2CNF A;  3F99 A;  1OET A;  2QCT A;  2QDC A;  1ZCL A;  3S4E A;  1T48 A;  2CMC A;  4KYR A;  3V0I A;  2JJD A;  1PYN A;  1G1H A;  1FPR A;  1VHR A;  1ONY A;  4BJO A;  1OEU A;  2R0B A;  2I6J A;  2BIJ A;  1SUG A;  1D5R A;  1WCH A;  1R6H A;  2VEU A;  3ZMQ A;  3V0J A;  2HC1 A;  1U26 A;  5K25 A;  1P15 A;  3OMH A;  2CNG A;  1WAX A;  5J8R A;  3O5X A;  3BRH A;  2GWO A;  4QUM A;  1RPM A;  4ICZ A;  2QDP A;  4YAA A;  3A5K A;  4GFV A;  2VEV A;  2J16 A;  3ZM1 A;  2HY3 A;  1Q6N A;  2I75 A;  1QXK A;  4GS0 A;  3F9B A;  1G1F A; 
#chains in the Genus database with same CATH topology
 1PTU A;  3QCH A;  1PH0 A;  4OHE A;  3V0E A;  3F9A A;  1C88 A;  1Q6T A;  1A5Y A;  3A5J A;  4OHD A;  3D1H A;  3V0F A;  5K9V A;  3MVN A;  1G4W R;  2H03 A;  2OOQ A;  3F81 A;  2B49 A;  4H1O A;  4QBW A;  1RXD A;  5K23 A;  1Q6J A;  3N2A A;  2CNE A;  4D3Q A;  5BX1 A;  1OEV A;  2I6I A;  5BZZ A;  1JBV A;  3S3H A;  3ZM3 A;  2HC2 A;  1J6U A;  1BZC A;  3O3L A;  3QCL A;  3EB1 A;  4RH9 A;  2F46 A;  4BPC A;  2HNP A;  1JBW A;  1U24 A;  1XM2 A;  2VTD A;  4PVG A;  1I9T A;  2B07 A;  1C85 A;  2M3V A;  2F00 A;  2MBC A;  2BV5 A;  3QCB A;  2QBP A;  5EHP A;  3QCI A;  1GG4 A;  1C84 A;  2B4O A;  1ECV A;  2CFV A;  3D1O A;  3QCD A;  4UAG A;  4NWF A;  2I3U A;  1PTV A;  3RZ2 A;  1P31 A;  1G7F A;  4GE5 A;  2ESB A;  2H04 A;  2H4G A;  1OEO X;  2IMG A;  1Q1M A;  4ZN5 A;  2C46 A;  1E8C A;  3PS5 A;  1NO6 A;  1NNY A;  1XRI A;  4R30 A;  2WJP A;  3I80 A;  4CVL A;  3GXH A;  4S0G A;  5KAB A;  5K22 A;  3EU0 A;  3U96 A;  1PTT A;  2PSZ A;  5A5E A;  3RGO A;  1T4J A;  2QEP A;  4JMJ A;  2AHS A;  2CMB A;  2HCM A;  2QCJ A;  2FH7 A;  1P3D A;  2QBS A;  2NT2 A;  1GQQ A;  2E0T A;  4WU3 A;  1FPZ A;  4IKC A;  3S4O A;  1KAV A;  2AZR A;  3MOZ A;  4HV4 A;  2F6Y A;  1PTY A;  4HJP A;  2G59 A;  1YPT A;  2I4H A;  3QCK A;  2Y67 A;  1ONZ A;  3QCJ A;  3BLU A;  5K24 A;  2F6T A;  5KAD A;  1L8K A;  2I42 A;  2P4D A;  3ZL8 A;  1PA9 A;  4CVK A;  2NV5 A;  3HN7 A;  4RHG A;  2VEX A;  4HJQ A;  3D1Q A;  4C13 A;  4BUC A;  2F6W A;  4Z6B A;  4JMK A;  2Y96 A;  2Y66 A;  2X5O A;  2CM8 A;  1U25 A;  5KA1 A;  2B4P A;  4GRZ A;  4GE2 A;  2GC6 A;  3ZM6 A;  2H02 A;  4GWF A;  1OES A;  1Q6S A;  1GFY A;  1YGR A;  2OUD A;  5KA7 A;  1XXP A;  4RKK A;  2Q05 A;  2F6F A;  1KAK A;  4H34 A;  3AWF A;  2F6Z A;  4DGX A;  5EHR A;  3BLT A;  3I36 A;  3PYZ A;  3S3E A;  4QUN A;  2HNQ A;  1LQF A;  4RI4 A;  3D44 A;  1M3G A;  1G4U S;  3LJ8 A;  2NZ6 A;  3QKQ A;  3CWE A;  1ZZW A;  2F71 A;  2BGD A;  4Y14 A;  5BUG A;  3ZM2 A;  3O4U A;  3V0H A;  3QCM A;  5GTJ A;  1I9S A;  3RGQ A;  1NWE A;  1YN9 A;  2UUP A;  2NLK A;  1I57 A;  1G1G A;  3UAG A;  1Q6P A;  2I6O A;  4RDD A;  2CM7 A;  4QBE A;  5KA2 A;  2PBN A;  3OLR A;  3QCE A;  4R0S A;  2UAG A;  2Y68 A;  1C86 A;  4MBB A;  1ZCK A;  1XXV A;  2VOR A;  1EEH A;  4JNB A;  1YTS A;  3EMU A;  1W7K A;  3ZM0 A;  2A3K A;  4ZRT A;  1YFO A;  2I3R A;  2QBR A;  2Y1O A;  4D3R A;  4J51 A;  3EZZ A;  1EEN A;  3QCZ A;  2HB1 A;  3QCC A;  4KYQ A;  1LYV A;  1JF7 A;  2GCB A;  1OHE A;  3MOW A;  1O5Z A;  2F6V A;  2ZMM A;  4Y2E A;  5KA3 A;  2HVL A;  3O4T A;  4TVV A;  1E0D A;  1V3A A;  2A8B A;  2PT0 A;  3D42 A;  3CM3 A;  2CNH A;  1BZH A;  1EEO A;  1T49 A;  1NL9 A;  4WTY A;  4GFU A;  3ZM5 A;  3AWE A;  4OHH A;  2CM3 A;  2WTZ A;  1YTN A;  2H4K A;  2PQ5 A;  5KA9 A;  2ZN7 A;  3QCF A;  1OHD A;  3F41 A;  2OC3 A;  2G6Z A;  4GRY A;  4QAH A;  2JFH A;  4AZ1 A;  2J16 B;  2VEW A;  2QBQ A;  5LXQ B;  1YGU A;  1GWZ A;  4R0T A;  3S3K A;  3ZMP A;  1QZ0 A;  2FJN A;  3NRS A;  4D3P A;  2B4S A;  2CMA A;  3M4U A;  4ERC A;  4HRF A;  3S3F A;  4DGP A;  5K9W A;  2I4G A;  3NME A;  5HDE A;  4WOH A;  2J17 A;  4NND A;  1NWL A;  1ZC0 A;  3EAX A;  5I6V A;  2VEY A;  2QDM A;  2Y2F A;  1PXH A;  1C87 A;  4QAP A;  1UAG A;  1GQY A;  5KA4 A;  1X24 A;  2BZL A;  3GXG A;  2NT7 A;  1MKP A;  3AWG A;  2PA5 A;  2OZ5 A;  5AWX A;  3V0D A;  5KAA A;  4RH5 A;  3QKP A;  3QCN A;  2RF6 A;  2GP0 A;  2HXP A;  3BM8 A;  4RI5 A;  2CM2 A;  3N0A A;  3V0G A;  1FGS A;  3I7Z A;  5IBM A;  4OHL A;  4I8N A;  3D9C A;  1Q6M A;  4NX8 A;  2B4U A;  1C83 A;  1LAR A;  1NZ7 A;  2YDU A;  2SHP A;  5IBS A;  1BZJ A;  1L8G A;  2F70 A;  2FJM A;  2DXP A;  3QCG A;  1YTW A;  2GC5 A;  2JFF A;  3ZV2 A;  1OEM X;  1YWF A;  5KA8 A;  2NTA A;  4NYH A;  4C12 A;  4ZIY A;  2I1Y A;  2I6M A;  1PA1 A;  4NWG A;  4B04 A;  1OHC A;  1XBO A;  2I4E A;  5A5F A;  3SME A;  3MMJ A;  2CNI A;  2P6X A;  4ZI4 A;  2GJT A;  2Q47 A;  5KA0 A;  2BGE A;  3H2X A;  2WGP A;  3B7O A;  3RO1 A;  1FQ1 A;  1G7G A;  2CJZ A;  1JLN A;  1YZ4 A;  1AAX A;  2I6P A;  2GCA A;  2H4V A;  4KI9 A;  5KAC A;  4JBC A;  3O4S A;  2B3O A;  4GE6 A;  1J4X A;  3SR9 A;  2PI7 A;  2I5X A;  4PYH A;  5BZX A;  4BUB A;  1WRM A;  4YR8 B;  5MMZ B;  4OHI A;  4WU2 A;  2C7S A;  5M43 A;  2CNF A;  3F99 A;  1OET A;  2QCT A;  2QDC A;  1ZCL A;  2XJA A;  4QF5 A;  3S4E A;  1T48 A;  2CMC A;  2VTE A;  4KYR A;  3V0I A;  2JJD A;  1PYN A;  1G1H A;  1FPR A;  2JFG A;  1VHR A;  4CVM A;  1ONY A;  4BJO A;  1OEU A;  2R0B A;  2AM2 A;  2I6J A;  2BIJ A;  1SUG A;  1D5R A;  1WCH A;  1R6H A;  2VEU A;  3ZMQ A;  3V0J A;  2UUO A;  2HC1 A;  1U26 A;  5K25 A;  1P15 A;  3OMH A;  2CNG A;  1WAX A;  5J8R A;  3LK7 A;  3O5X A;  2XPC A;  3BRH A;  2GWO A;  4QUM A;  2VOS A;  1RPM A;  4ICZ A;  2QDP A;  4QDI A;  4YAA A;  3A5K A;  4GFV A;  2VEV A;  2J16 A;  3ZM1 A;  2HY3 A;  1Q6N A;  2I75 A;  2AM1 A;  1QXK A;  4GS0 A;  3F9B A;  1G1F A;  1W78 A; 
#chains in the Genus database with same CATH homology
 1PTU A;  3QCH A;  1PH0 A;  4OHE A;  3V0E A;  3F9A A;  1C88 A;  1Q6T A;  1A5Y A;  3A5J A;  4OHD A;  3D1H A;  3V0F A;  5K9V A;  1G4W R;  2H03 A;  2OOQ A;  3F81 A;  2B49 A;  4H1O A;  4QBW A;  1RXD A;  5K23 A;  1Q6J A;  4D3Q A;  2CNE A;  5BX1 A;  1OEV A;  2I6I A;  5BZZ A;  3S3H A;  3ZM3 A;  2HC2 A;  1BZC A;  3O3L A;  3QCL A;  3EB1 A;  4RH9 A;  2F46 A;  4BPC A;  2HNP A;  1U24 A;  1XM2 A;  4PVG A;  1I9T A;  2B07 A;  1C85 A;  2M3V A;  2MBC A;  2BV5 A;  3QCB A;  2QBP A;  5EHP A;  3QCI A;  1C84 A;  2B4O A;  1ECV A;  2CFV A;  3D1O A;  3QCD A;  4NWF A;  2I3U A;  1PTV A;  3RZ2 A;  1G7F A;  4GE5 A;  2ESB A;  2H04 A;  2H4G A;  1OEO X;  2IMG A;  1Q1M A;  4ZN5 A;  2C46 A;  3PS5 A;  1NO6 A;  1NNY A;  1XRI A;  4R30 A;  3I80 A;  3GXH A;  4S0G A;  5KAB A;  5K22 A;  3EU0 A;  3U96 A;  1PTT A;  2PSZ A;  3RGO A;  1T4J A;  2QEP A;  4JMJ A;  2AHS A;  2CMB A;  2HCM A;  2QCJ A;  2FH7 A;  2QBS A;  2NT2 A;  2E0T A;  4WU3 A;  1FPZ A;  4IKC A;  3S4O A;  1KAV A;  2AZR A;  3MOZ A;  2F6Y A;  1PTY A;  4HJP A;  2G59 A;  1YPT A;  2I4H A;  3QCK A;  1ONZ A;  3QCJ A;  3BLU A;  5K24 A;  2F6T A;  5KAD A;  1L8K A;  2I42 A;  2P4D A;  1PA9 A;  2NV5 A;  4RHG A;  2VEX A;  4HJQ A;  3D1Q A;  2F6W A;  4Z6B A;  4JMK A;  2Y96 A;  2CM8 A;  1U25 A;  5KA1 A;  2B4P A;  4GRZ A;  4GE2 A;  2H02 A;  4GWF A;  1OES A;  1Q6S A;  1GFY A;  1YGR A;  2OUD A;  5KA7 A;  1XXP A;  4RKK A;  2Q05 A;  2F6F A;  1KAK A;  4H34 A;  3AWF A;  2F6Z A;  4DGX A;  5EHR A;  3BLT A;  3I36 A;  3S3E A;  4QUN A;  2HNQ A;  1LQF A;  4RI4 A;  3D44 A;  1M3G A;  1G4U S;  3LJ8 A;  2NZ6 A;  3QKQ A;  3CWE A;  1ZZW A;  2F71 A;  2BGD A;  4Y14 A;  5BUG A;  3ZM2 A;  3O4U A;  3V0H A;  3QCM A;  5GTJ A;  1I9S A;  3RGQ A;  1NWE A;  1YN9 A;  2NLK A;  1I57 A;  1G1G A;  1Q6P A;  2I6O A;  4RDD A;  2CM7 A;  4QBE A;  5KA2 A;  2PBN A;  3OLR A;  3QCE A;  4R0S A;  1C86 A;  4MBB A;  1ZCK A;  1XXV A;  4JNB A;  1YTS A;  3EMU A;  3ZM0 A;  2A3K A;  4ZRT A;  1YFO A;  2I3R A;  2QBR A;  4D3R A;  4J51 A;  3EZZ A;  1EEN A;  2HB1 A;  3QCC A;  4KYQ A;  1LYV A;  1JF7 A;  1OHE A;  3MOW A;  2F6V A;  2ZMM A;  4Y2E A;  5KA3 A;  2HVL A;  3O4T A;  4TVV A;  1V3A A;  2A8B A;  2PT0 A;  3D42 A;  3CM3 A;  2CNH A;  1BZH A;  1EEO A;  1T49 A;  1NL9 A;  4WTY A;  4GFU A;  3AWE A;  4OHH A;  2CM3 A;  1YTN A;  2H4K A;  2PQ5 A;  5KA9 A;  2ZN7 A;  3QCF A;  1OHD A;  3F41 A;  2OC3 A;  2G6Z A;  4GRY A;  4QAH A;  4AZ1 A;  2J16 B;  2VEW A;  2QBQ A;  5LXQ B;  1YGU A;  1GWZ A;  4R0T A;  3S3K A;  3ZMP A;  1QZ0 A;  2FJN A;  4D3P A;  2B4S A;  2CMA A;  3M4U A;  4ERC A;  4HRF A;  3S3F A;  4DGP A;  5K9W A;  2I4G A;  3NME A;  5HDE A;  4WOH A;  2J17 A;  4NND A;  1NWL A;  1ZC0 A;  3EAX A;  5I6V A;  2VEY A;  2QDM A;  2Y2F A;  1PXH A;  1C87 A;  4QAP A;  5KA4 A;  1X24 A;  2BZL A;  3GXG A;  2NT7 A;  1MKP A;  3AWG A;  2PA5 A;  2OZ5 A;  5AWX A;  3V0D A;  5KAA A;  4RH5 A;  3QKP A;  3QCN A;  2RF6 A;  2GP0 A;  2HXP A;  3BM8 A;  4RI5 A;  2CM2 A;  3N0A A;  3V0G A;  3I7Z A;  5IBM A;  4OHL A;  4I8N A;  3D9C A;  1Q6M A;  4NX8 A;  2B4U A;  1C83 A;  1LAR A;  1NZ7 A;  2YDU A;  2SHP A;  5IBS A;  1BZJ A;  1L8G A;  2F70 A;  2FJM A;  2DXP A;  3QCG A;  1YTW A;  3ZV2 A;  1OEM X;  1YWF A;  5KA8 A;  2NTA A;  4NYH A;  2I1Y A;  2I6M A;  1PA1 A;  4NWG A;  4B04 A;  1OHC A;  1XBO A;  2I4E A;  3SME A;  3MMJ A;  2CNI A;  2P6X A;  4ZI4 A;  2GJT A;  2Q47 A;  5KA0 A;  2BGE A;  3H2X A;  2WGP A;  3B7O A;  3RO1 A;  1FQ1 A;  1G7G A;  2CJZ A;  1JLN A;  1YZ4 A;  1AAX A;  2I6P A;  2H4V A;  4KI9 A;  5KAC A;  4JBC A;  3O4S A;  2B3O A;  4GE6 A;  1J4X A;  3SR9 A;  2PI7 A;  2I5X A;  4PYH A;  5BZX A;  1WRM A;  4YR8 B;  5MMZ B;  4OHI A;  4WU2 A;  2C7S A;  5M43 A;  2CNF A;  3F99 A;  1OET A;  2QCT A;  2QDC A;  1ZCL A;  3S4E A;  1T48 A;  2CMC A;  4KYR A;  3V0I A;  2JJD A;  1PYN A;  1G1H A;  1FPR A;  1VHR A;  1ONY A;  4BJO A;  1OEU A;  2R0B A;  2I6J A;  2BIJ A;  1SUG A;  1D5R A;  1WCH A;  1R6H A;  2VEU A;  3ZMQ A;  3V0J A;  2HC1 A;  1U26 A;  5K25 A;  1P15 A;  3OMH A;  2CNG A;  1WAX A;  5J8R A;  3O5X A;  3BRH A;  2GWO A;  4QUM A;  1RPM A;  4ICZ A;  2QDP A;  4YAA A;  3A5K A;  4GFV A;  2VEV A;  2J16 A;  3ZM1 A;  2HY3 A;  1Q6N A;  2I75 A;  1QXK A;  4GS0 A;  3F9B A;  1G1F A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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