2IO4B

Crystal structure of pcna12 dimer from sulfolobus solfataricus.
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
246
structure length
246
Chain Sequence
MMKAKVIDAVSFSYILRTVGDFLSEANFIVTKEGIRVSGIDPSRVVFLDIFLPSSYFEGFEVSQEKEIIGFKLEDVNDILKRVLKDDTLILSSNESKLTLTFDGEFTRSFELPLIQVESTQPPSVNLEFPFKAQLLTITFADIIDELSDLGEVLNIHSKENKLYFEVIGDLSTAKVELSTDNGTLLEASGADVSSSYGMEYVANTTKMRRASDSMELYFGSQIPLKLRFKLPQEGYGDFYIAPRAD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening.
pubmed doi rcsb
molecule keywords DNA polymerase sliding clamp B
molecule tags Dna binding protein
source organism Sulfolobus solfataricus
total genus 59
structure length 246
sequence length 246
chains with identical sequence D
ec nomenclature
pdb deposition date 2006-10-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00705 PCNA_N Proliferating cell nuclear antigen, N-terminal domain
B PF02747 PCNA_C Proliferating cell nuclear antigen, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.70.10.10 Alpha Beta Box Proliferating Cell Nuclear Antigen Proliferating Cell Nuclear Antigen 2io4B00
2OD8A 5HACA 2ZVLA 2IZOC 2NTIA 4HK1A 1IZ4A 2HIKA 2IO4B 3G65B 1DMLA 1GE8A 3V61B 5CFKA 4ZTDA 3P83A 5B7OA 3GGRA 3U5ZF 5DA7A 3FDSC 3U60F 1PLQA 5JNED 2ZVMA 3F1WA 3AIZA 3A1JB 3AIZC 3HI8A 1VYJA 3G65C 1UL1A 3LX2A 3K4XA 2ZVVA 5H0TA 3GPNA 2HIIB 4L6PA 1IZ5A 4RJFA 2NTIB 3FDSD 3P91A 2HIKB 3HSLX 3GPMA 2IJXA 2IX2B 3AIXA 4D2GA 1U7BA 3I2MX 2Z0LA 5IY4A 2IO4A 3G65A 4L60A 4YHRA 1RXMA 3IFVA 1W60A 1CZDA 1ISQA 1SXJF 5IWDA 1YYPA 3A1JC 3GGRB 3LX1A 1RXZA 1T6LA 2HIIC 5E0UA 4TR6A 1B8HA 2NTIC 5E0TA 5AUJA 2AVTA 2HIKC 3VKXA 1VYMA 3TBLA 1B77A 1UD9A 3GGRC 1PLRA 2IZOB 3U61F 2IX2C 2IX2A 5IXAA 3P87A 2AWAA 3V62B 1AXCA 3A1JA 5DAIA 4CS5A 2ZVWA 2ZVKA 3AIXB 3V60B 5E0VA 3WGWA 3A2FB 1RWZA 2HIIA 5A6DA 1U76A
chains in the Genus database with same CATH superfamily
2OD8A 5HACA 2ZVLA 2IZOC 2NTIA 4HK1A 1IZ4A 2HIKA 2IO4B 3G65B 1DMLA 1GE8A 3V61B 5CFKA 4ZTDA 3P83A 5B7OA 3GGRA 3U5ZF 5DA7A 3FDSC 3U60F 1PLQA 5JNED 2ZVMA 3F1WA 3AIZA 3A1JB 3AIZC 3HI8A 1VYJA 3G65C 1UL1A 3LX2A 3K4XA 2ZVVA 5H0TA 3GPNA 2HIIB 4L6PA 1IZ5A 4RJFA 2NTIB 3FDSD 3P91A 2HIKB 3HSLX 3GPMA 2IJXA 2IX2B 3AIXA 4D2GA 1U7BA 3I2MX 2Z0LA 5IY4A 2IO4A 3G65A 4L60A 4YHRA 1RXMA 3IFVA 1W60A 1CZDA 1ISQA 1SXJF 5IWDA 1YYPA 3A1JC 3GGRB 3LX1A 1RXZA 1T6LA 2HIIC 5E0UA 4TR6A 1B8HA 2NTIC 5E0TA 5AUJA 2AVTA 2HIKC 3VKXA 1VYMA 3TBLA 1B77A 1UD9A 3GGRC 1PLRA 2IZOB 3U61F 2IX2C 2IX2A 5IXAA 3P87A 2AWAA 3V62B 1AXCA 3A1JA 5DAIA 4CS5A 2ZVWA 2ZVKA 3AIXB 3V60B 5E0VA 3WGWA 3A2FB 1RWZA 2HIIA 5A6DA 1U76A
chains in the Genus database with same CATH topology
2OD8A 5HACA 2ZVLA 2IZOC 2NTIA 4HK1A 1IZ4A 2HIKA 2IO4B 3G65B 1DMLA 1GE8A 3V61B 5CFKA 4ZTDA 3P83A 5B7OA 3GGRA 3U5ZF 5DA7A 3FDSC 3U60F 1PLQA 5JNED 2ZVMA 3F1WA 3AIZA 3A1JB 3AIZC 3HI8A 1VYJA 3G65C 1UL1A 3LX2A 3K4XA 2ZVVA 5H0TA 3GPNA 2HIIB 4L6PA 1IZ5A 4RJFA 2NTIB 3FDSD 3P91A 2HIKB 3HSLX 3GPMA 2IJXA 2IX2B 3AIXA 4D2GA 1U7BA 3I2MX 2Z0LA 5IY4A 2IO4A 3G65A 4L60A 4YHRA 1RXMA 3IFVA 1W60A 1CZDA 1ISQA 1SXJF 5IWDA 1YYPA 3A1JC 3GGRB 3LX1A 1RXZA 1T6LA 2HIIC 5E0UA 4TR6A 1B8HA 2NTIC 5E0TA 5AUJA 2AVTA 2HIKC 3VKXA 1VYMA 3TBLA 1B77A 1UD9A 3GGRC 1PLRA 2IZOB 3U61F 2IX2C 2IX2A 5IXAA 3P87A 2AWAA 3V62B 1AXCA 3A1JA 5DAIA 4CS5A 2ZVWA 2ZVKA 3AIXB 3V60B 5E0VA 3WGWA 3A2FB 1RWZA 2HIIA 5A6DA 1U76A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OD8 A;  5HAC A;  2ZVL A;  2IZO C;  2NTI A;  4HK1 A;  1IZ4 A;  2HIK A;  2IO4 B;  3G65 B;  1DML A;  1GE8 A;  3V61 B;  5CFK A;  4ZTD A;  3P83 A;  5B7O A;  3GGR A;  3U5Z F;  5DA7 A;  3FDS C;  3U60 F;  1PLQ A;  5JNE D;  2ZVM A;  3F1W A;  3AIZ A;  3A1J B;  3AIZ C;  3HI8 A;  1VYJ A;  3G65 C;  1UL1 A;  3LX2 A;  3K4X A;  2ZVV A;  5H0T A;  3GPN A;  2HII B;  4L6P A;  1IZ5 A;  4RJF A;  2NTI B;  3FDS D;  3P91 A;  2HIK B;  3HSL X;  3GPM A;  2IJX A;  2IX2 B;  3AIX A;  4D2G A;  1U7B A;  3I2M X;  2Z0L A;  5IY4 A;  2IO4 A;  3G65 A;  4L60 A;  4YHR A;  1RXM A;  3IFV A;  1W60 A;  1CZD A;  1ISQ A;  1SXJ F;  5IWD A;  1YYP A;  3A1J C;  3GGR B;  3LX1 A;  1RXZ A;  1T6L A;  2HII C;  5E0U A;  4TR6 A;  1B8H A;  2NTI C;  5E0T A;  5AUJ A;  2AVT A;  2HIK C;  3VKX A;  1VYM A;  3TBL A;  1B77 A;  1UD9 A;  3GGR C;  1PLR A;  2IZO B;  3U61 F;  2IX2 C;  2IX2 A;  5IXA A;  3P87 A;  2AWA A;  3V62 B;  1AXC A;  3A1J A;  5DAI A;  4CS5 A;  2ZVW A;  2ZVK A;  3AIX B;  3V60 B;  5E0V A;  3WGW A;  3A2F B;  1RWZ A;  2HII A;  5A6D A;  1U76 A; 
#chains in the Genus database with same CATH topology
 2OD8 A;  5HAC A;  2ZVL A;  2IZO C;  2NTI A;  4HK1 A;  1IZ4 A;  2HIK A;  2IO4 B;  3G65 B;  1DML A;  1GE8 A;  3V61 B;  5CFK A;  4ZTD A;  3P83 A;  5B7O A;  3GGR A;  3U5Z F;  5DA7 A;  3FDS C;  3U60 F;  1PLQ A;  5JNE D;  2ZVM A;  3F1W A;  3AIZ A;  3A1J B;  3AIZ C;  3HI8 A;  1VYJ A;  3G65 C;  1UL1 A;  3LX2 A;  3K4X A;  2ZVV A;  5H0T A;  3GPN A;  2HII B;  4L6P A;  1IZ5 A;  4RJF A;  2NTI B;  3FDS D;  3P91 A;  2HIK B;  3HSL X;  3GPM A;  2IJX A;  2IX2 B;  3AIX A;  4D2G A;  1U7B A;  3I2M X;  2Z0L A;  5IY4 A;  2IO4 A;  3G65 A;  4L60 A;  4YHR A;  1RXM A;  3IFV A;  1W60 A;  1CZD A;  1ISQ A;  1SXJ F;  5IWD A;  1YYP A;  3A1J C;  3GGR B;  3LX1 A;  1RXZ A;  1T6L A;  2HII C;  5E0U A;  4TR6 A;  1B8H A;  2NTI C;  5E0T A;  5AUJ A;  2AVT A;  2HIK C;  3VKX A;  1VYM A;  3TBL A;  1B77 A;  1UD9 A;  3GGR C;  1PLR A;  2IZO B;  3U61 F;  2IX2 C;  2IX2 A;  5IXA A;  3P87 A;  2AWA A;  3V62 B;  1AXC A;  3A1J A;  5DAI A;  4CS5 A;  2ZVW A;  2ZVK A;  3AIX B;  3V60 B;  5E0V A;  3WGW A;  3A2F B;  1RWZ A;  2HII A;  5A6D A;  1U76 A; 
#chains in the Genus database with same CATH homology
 2OD8 A;  5HAC A;  2ZVL A;  2IZO C;  2NTI A;  4HK1 A;  1IZ4 A;  2HIK A;  2IO4 B;  3G65 B;  1DML A;  1GE8 A;  3V61 B;  5CFK A;  4ZTD A;  3P83 A;  5B7O A;  3GGR A;  3U5Z F;  5DA7 A;  3FDS C;  3U60 F;  1PLQ A;  5JNE D;  2ZVM A;  3F1W A;  3AIZ A;  3A1J B;  3AIZ C;  3HI8 A;  1VYJ A;  3G65 C;  1UL1 A;  3LX2 A;  3K4X A;  2ZVV A;  5H0T A;  3GPN A;  2HII B;  4L6P A;  1IZ5 A;  4RJF A;  2NTI B;  3FDS D;  3P91 A;  2HIK B;  3HSL X;  3GPM A;  2IJX A;  2IX2 B;  3AIX A;  4D2G A;  1U7B A;  3I2M X;  2Z0L A;  5IY4 A;  2IO4 A;  3G65 A;  4L60 A;  4YHR A;  1RXM A;  3IFV A;  1W60 A;  1CZD A;  1ISQ A;  1SXJ F;  5IWD A;  1YYP A;  3A1J C;  3GGR B;  3LX1 A;  1RXZ A;  1T6L A;  2HII C;  5E0U A;  4TR6 A;  1B8H A;  2NTI C;  5E0T A;  5AUJ A;  2AVT A;  2HIK C;  3VKX A;  1VYM A;  3TBL A;  1B77 A;  1UD9 A;  3GGR C;  1PLR A;  2IZO B;  3U61 F;  2IX2 C;  2IX2 A;  5IXA A;  3P87 A;  2AWA A;  3V62 B;  1AXC A;  3A1J A;  5DAI A;  4CS5 A;  2ZVW A;  2ZVK A;  3AIX B;  3V60 B;  5E0V A;  3WGW A;  3A2F B;  1RWZ A;  2HII A;  5A6D A;  1U76 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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