2ISTA

Crystal structure of rlud from e. coli
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
324
structure length
321
Chain Sequence
AQRVQLTATVSENQLGQRLDQALAEMFPDYSRSRIKEWILDQRVLVNGKVCDKPKEKVLGGEQVAINAEIERFEPQDIPLDIVYEDEDIIIINKPRDLVVHPGAGNPDGTVLNALLHYYPPIADVPRAGIVHRLDKDTTGLMVVAKTVPAQTRLVESLQRREITREYEAVAIGHMTAGGTVDEPISRHPTKRTHMAVHPMGKPAVTHYRIMEHFRVHTRLRLRLETGRTHQIRVHMAHITHPLVGDPVYGGRPRPPKGASEAFISTLRKFDRQALHATMLRLYHPISGIEMEWHAPIPQDMVELIEVMRADFEEHKDEVDW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Ribosomal large subunit pseudouridine synthase D
publication title Crystal structure of RluD from E. coli
rcsb
source organism Escherichia coli
molecule tags Isomerase
total genus 86
structure length 321
sequence length 324
ec nomenclature ec 5.4.99.23: 23S rRNA pseudouridine(1911/1915/1917) synthase.
pdb deposition date 2006-10-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00849 PseudoU_synth_2 RNA pseudouridylate synthase
A PF01479 S4 S4 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.290.10 Alpha Beta Roll Structural Genomics Hypothetical 15.5 Kd Protein In mrcA-pckA Intergenic Region; Chain A RNA-binding S4 domain 2istA01
3.30.2350.10 Alpha Beta 2-Layer Sandwich Pseudouridine synthase Pseudouridine synthase 2istA02
3KBGA 4DR2D 3OTOD 4DR4D 1PRZA 4AQYD 4NXMD 1ZL3A 1XPIA 4LF4D 4DV4D 2UXDD 1H3FA 3HJWA 4JI5D 4YHHD 1FJGD 1XMQD 4LF7D 1DM9A 1XNQD 2EY4A 4KHPD 4JV5D 2AB4A 1N36D 2HVYA 1P9KA 1HNWD 3LWPA 1IBKD 4GKKD 4DV0D 3LWRA 1H3EA 4YY3D 4LF6D 3U28A 4OUDA 5LMUD 4DV6D 1FKAD 4JI8D 1HNZD 1JH3A 1ZE1A 3LWVA 2K6PA 1SGVA 3HJYA 1XNRD 1J5ED 4JI4D 2VQED 2AUSA 3UAIA 4DV5D 1QYUA 4LFBD 4DV1D 2RFKA 4B3RD 4X62D 2F4VD 4DV2D 1HR0D 4JI0D 2VQFD 4DUYD 5IWAD 4LFAD 2HHHD 5LMND 2UUAD 1V9KA 1R3EA 1R3FA 1K8WA 1C06A 2APOA 4NXND 4B3TD 3HP7A 4GKJD 4DUZD 3DH3A 2UU9D 4LGTA 2ZM6D 4K0KD 3LWOA 4OX9D 1I94D 4DR5D 5BR8D 2UUBD 4LFCD 1IBMD 1N32D 1XMOD 2KTLA 1IBLD 4JI3D 2UXCD 1N34D 1HNXD 2ISTA 4X64D 4DV3D 4JI1D 4JYAD 4LF9D 4X66D 4DR6D 1N33D 4B3SD 4DR7D 3T1HD 2UUCD 3LWQA 4DR3D 2I82A 1V9FA 3HAXA 4DR1D 4LABA 3MQKA 1KSVA 2JANA 1KSLA 4B3MD 2E5LD 1VIOA 4JI2D 4X65D 4JI7D 1ZE2A 3T1YD 4DV7D 2UXBD 1KSKA 4LF5D 4LF8D 4JI6D 1C05A
chains in the Genus database with same CATH superfamily
3KBGA 4DR2D 1Y8XB 3OTOD 3J80E 4DR4D 1PRZA 4AQYD 4NXMD 1SZWA 1ZL3A 1XPIA 4LF4D 4DV4D 2UXDD 1H3FA 5FQ2B 3HJWA 4JI5D 4YHHD 1FJGD 5A2QE 1XMQD 4LF7D 1DM9A 1XNQD 2EY4A 4KHPD 4JV5D 2AB4A 1N36D 2HVYA 1P9KA 1HNWD 3LWPA 1IBKD 4GKKD 4DV0D 3LWRA 1H3EA 4YY3D 4LF6D 3U28A 4OUDA 4NNJA 1Z2ZA 5LMUD 4DV6D 1FKAD 4JI8D 1HNZD 1JH3A 1ZE1A 3LWVA 3J7AF 2K6PA 1SGVA 3HJYA 2LQ7A 1J5ED 4JI4D 1XNRD 2VQED 2ZTBA 1SB7A 2AUSA 3UAIA 4DV5D 1QYUA 4LFBD 3J81E 4DV1D 2RFKA 1SI7A 4B3RD 4X62D 2F4VD 4DV2D 1HR0D 1Y8RB 5LL6S 4JI0D 1Y8QB 4DUYD 5IWAD 4LFAD 2HHHD 2I1SA 5LMND 2UUAD 1V9KA 1R3EA 1R3FA 1K8WA 1C06A 5FLXE 2APOA 4NXND 4B3TD 4JI6D 3HP7A 4GKJD 4DUZD 3DH3A 2UU9D 4LGTA 2ZM6D 3ONHA 4K0KD 5KNLA 3LWOA 3JAME 3CMMA 4OX9D 1I94D 4DR5D 5BR8D 2UUBD 4LFCD 1IBMD 1N32D 1XMOD 2KTLA 1IBLD 4JI3D 2UXCD 1N34D 2ISTA 1HNXD 5IT9E 4X64D 4DV3D 3FN1A 4JI1D 4JYAD 4LF9D 4X66D 4DR6D 1N33D 4B3SD 4DR7D 3KYCB 3T1HD 2UUCD 3LWQA 4DR3D 2I82A 1V9FA 3KYDB 3HAXA 4DR1D 4LABA 2NVUB 3MQKA 1KSVA 2JANA 1KSLA 4B3MD 2E5LD 3ONGA 1VIOA 4JI2D 4X65D 4II2A 4II3A 4JI7D 1ZE2A 3T1YD 4DV7D 2UXBD 1KSKA 4W5VB 4LF5D 4LF8D 2VQFD 1C05A
chains in the Genus database with same CATH topology
3KBGA 4DR2D 3OTOD 4DR4D 1PRZA 4AQYD 4NXMD 1SZWA 1ZL3A 1XPIA 4LF4D 4DV4D 2UXDD 1H3FA 3HJWA 4JI5D 4YHHD 1FJGD 1XMQD 4LF7D 1DM9A 1XNQD 2EY4A 4KHPD 4JV5D 2AB4A 1N36D 2HVYA 1P9KA 1HNWD 3LWPA 1IBKD 4GKKD 4DV0D 3LWRA 1H3EA 4YY3D 4LF6D 3U28A 4OUDA 1Z2ZA 5LMUD 4DV6D 1FKAD 4JI8D 1HNZD 1JH3A 1ZE1A 3LWVA 2K6PA 1SGVA 3HJYA 1XNRD 1J5ED 4JI4D 2VQED 2AUSA 1SB7A 3UAIA 4DV5D 1QYUA 4LFBD 4DV1D 2RFKA 1SI7A 4B3RD 4X62D 2F4VD 4DV2D 1HR0D 4JI0D 2VQFD 4DUYD 5IWAD 4LFAD 2HHHD 5LMND 2UUAD 1V9KA 1R3EA 1R3FA 1K8WA 1C06A 2APOA 4NXND 4B3TD 3HP7A 4GKJD 4DUZD 3DH3A 2UU9D 4LGTA 2ZM6D 4K0KD 3LWOA 4OX9D 1I94D 4DR5D 5BR8D 2UUBD 4LFCD 1IBMD 1N32D 1XMOD 2KTLA 1IBLD 4JI3D 2UXCD 1N34D 1HNXD 2ISTA 4X64D 4DV3D 4JI1D 4JYAD 4LF9D 4X66D 4DR6D 1N33D 4B3SD 4DR7D 3T1HD 2UUCD 3LWQA 4DR3D 2I82A 1V9FA 3HAXA 4DR1D 4LABA 3MQKA 1KSVA 2JANA 1KSLA 4B3MD 2E5LD 1VIOA 4JI2D 4X65D 4JI7D 1ZE2A 3T1YD 4DV7D 2UXBD 1KSKA 4LF5D 4LF8D 4JI6D 1C05A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KBG A;  4DR2 D;  3OTO D;  4DR4 D;  1PRZ A;  4AQY D;  4NXM D;  1ZL3 A;  1XPI A;  4LF4 D;  4DV4 D;  2UXD D;  1H3F A;  3HJW A;  4JI5 D;  4YHH D;  1FJG D;  1XMQ D;  4LF7 D;  1DM9 A;  1XNQ D;  2EY4 A;  4KHP D;  4JV5 D;  2AB4 A;  1N36 D;  2HVY A;  1P9K A;  1HNW D;  3LWP A;  1IBK D;  4GKK D;  4DV0 D;  3LWR A;  1H3E A;  4YY3 D;  4LF6 D;  3U28 A;  4OUD A;  5LMU D;  4DV6 D;  1FKA D;  4JI8 D;  1HNZ D;  1JH3 A;  1ZE1 A;  3LWV A;  2K6P A;  1SGV A;  3HJY A;  1XNR D;  1J5E D;  4JI4 D;  2VQE D;  2AUS A;  3UAI A;  4DV5 D;  1QYU A;  4LFB D;  4DV1 D;  2RFK A;  4B3R D;  4X62 D;  2F4V D;  4DV2 D;  1HR0 D;  4JI0 D;  2VQF D;  4DUY D;  5IWA D;  4LFA D;  2HHH D;  5LMN D;  2UUA D;  1V9K A;  1R3E A;  1R3F A;  1K8W A;  1C06 A;  2APO A;  4NXN D;  4B3T D;  3HP7 A;  4GKJ D;  4DUZ D;  3DH3 A;  2UU9 D;  4LGT A;  2ZM6 D;  4K0K D;  3LWO A;  4OX9 D;  1I94 D;  4DR5 D;  5BR8 D;  2UUB D;  4LFC D;  1IBM D;  1N32 D;  1XMO D;  2KTL A;  1IBL D;  4JI3 D;  2UXC D;  1N34 D;  1HNX D;  2IST A;  4X64 D;  4DV3 D;  4JI1 D;  4JYA D;  4LF9 D;  4X66 D;  4DR6 D;  1N33 D;  4B3S D;  4DR7 D;  3T1H D;  2UUC D;  3LWQ A;  4DR3 D;  2I82 A;  1V9F A;  3HAX A;  4DR1 D;  4LAB A;  3MQK A;  1KSV A;  2JAN A;  1KSL A;  4B3M D;  2E5L D;  1VIO A;  4JI2 D;  4X65 D;  4JI7 D;  1ZE2 A;  3T1Y D;  4DV7 D;  2UXB D;  1KSK A;  4LF5 D;  4LF8 D;  4JI6 D;  1C05 A; 
#chains in the Genus database with same CATH topology
 3KBG A;  4DR2 D;  1Y8X B;  3OTO D;  3J80 E;  4DR4 D;  1PRZ A;  4AQY D;  4NXM D;  1SZW A;  1ZL3 A;  1XPI A;  4LF4 D;  4DV4 D;  2UXD D;  1H3F A;  5FQ2 B;  3HJW A;  4JI5 D;  4YHH D;  1FJG D;  5A2Q E;  1XMQ D;  4LF7 D;  1DM9 A;  1XNQ D;  2EY4 A;  4KHP D;  4JV5 D;  2AB4 A;  1N36 D;  2HVY A;  1P9K A;  1HNW D;  3LWP A;  1IBK D;  4GKK D;  4DV0 D;  3LWR A;  1H3E A;  4YY3 D;  4LF6 D;  3U28 A;  4OUD A;  4NNJ A;  1Z2Z A;  5LMU D;  4DV6 D;  1FKA D;  4JI8 D;  1HNZ D;  1JH3 A;  1ZE1 A;  3LWV A;  3J7A F;  2K6P A;  1SGV A;  3HJY A;  2LQ7 A;  1J5E D;  4JI4 D;  1XNR D;  2VQE D;  2ZTB A;  1SB7 A;  2AUS A;  3UAI A;  4DV5 D;  1QYU A;  4LFB D;  3J81 E;  4DV1 D;  2RFK A;  1SI7 A;  4B3R D;  4X62 D;  2F4V D;  4DV2 D;  1HR0 D;  1Y8R B;  5LL6 S;  4JI0 D;  1Y8Q B;  4DUY D;  5IWA D;  4LFA D;  2HHH D;  2I1S A;  5LMN D;  2UUA D;  1V9K A;  1R3E A;  1R3F A;  1K8W A;  1C06 A;  5FLX E;  2APO A;  4NXN D;  4B3T D;  4JI6 D;  3HP7 A;  4GKJ D;  4DUZ D;  3DH3 A;  2UU9 D;  4LGT A;  2ZM6 D;  3ONH A;  4K0K D;  5KNL A;  3LWO A;  3JAM E;  3CMM A;  4OX9 D;  1I94 D;  4DR5 D;  5BR8 D;  2UUB D;  4LFC D;  1IBM D;  1N32 D;  1XMO D;  2KTL A;  1IBL D;  4JI3 D;  2UXC D;  1N34 D;  2IST A;  1HNX D;  5IT9 E;  4X64 D;  4DV3 D;  3FN1 A;  4JI1 D;  4JYA D;  4LF9 D;  4X66 D;  4DR6 D;  1N33 D;  4B3S D;  4DR7 D;  3KYC B;  3T1H D;  2UUC D;  3LWQ A;  4DR3 D;  2I82 A;  1V9F A;  3KYD B;  3HAX A;  4DR1 D;  4LAB A;  2NVU B;  3MQK A;  1KSV A;  2JAN A;  1KSL A;  4B3M D;  2E5L D;  3ONG A;  1VIO A;  4JI2 D;  4X65 D;  4II2 A;  4II3 A;  4JI7 D;  1ZE2 A;  3T1Y D;  4DV7 D;  2UXB D;  1KSK A;  4W5V B;  4LF5 D;  4LF8 D;  2VQF D;  1C05 A; 
#chains in the Genus database with same CATH homology
 3KBG A;  4DR2 D;  3OTO D;  4DR4 D;  1PRZ A;  4AQY D;  4NXM D;  1SZW A;  1ZL3 A;  1XPI A;  4LF4 D;  4DV4 D;  2UXD D;  1H3F A;  3HJW A;  4JI5 D;  4YHH D;  1FJG D;  1XMQ D;  4LF7 D;  1DM9 A;  1XNQ D;  2EY4 A;  4KHP D;  4JV5 D;  2AB4 A;  1N36 D;  2HVY A;  1P9K A;  1HNW D;  3LWP A;  1IBK D;  4GKK D;  4DV0 D;  3LWR A;  1H3E A;  4YY3 D;  4LF6 D;  3U28 A;  4OUD A;  1Z2Z A;  5LMU D;  4DV6 D;  1FKA D;  4JI8 D;  1HNZ D;  1JH3 A;  1ZE1 A;  3LWV A;  2K6P A;  1SGV A;  3HJY A;  1XNR D;  1J5E D;  4JI4 D;  2VQE D;  2AUS A;  1SB7 A;  3UAI A;  4DV5 D;  1QYU A;  4LFB D;  4DV1 D;  2RFK A;  1SI7 A;  4B3R D;  4X62 D;  2F4V D;  4DV2 D;  1HR0 D;  4JI0 D;  2VQF D;  4DUY D;  5IWA D;  4LFA D;  2HHH D;  5LMN D;  2UUA D;  1V9K A;  1R3E A;  1R3F A;  1K8W A;  1C06 A;  2APO A;  4NXN D;  4B3T D;  3HP7 A;  4GKJ D;  4DUZ D;  3DH3 A;  2UU9 D;  4LGT A;  2ZM6 D;  4K0K D;  3LWO A;  4OX9 D;  1I94 D;  4DR5 D;  5BR8 D;  2UUB D;  4LFC D;  1IBM D;  1N32 D;  1XMO D;  2KTL A;  1IBL D;  4JI3 D;  2UXC D;  1N34 D;  1HNX D;  2IST A;  4X64 D;  4DV3 D;  4JI1 D;  4JYA D;  4LF9 D;  4X66 D;  4DR6 D;  1N33 D;  4B3S D;  4DR7 D;  3T1H D;  2UUC D;  3LWQ A;  4DR3 D;  2I82 A;  1V9F A;  3HAX A;  4DR1 D;  4LAB A;  3MQK A;  1KSV A;  2JAN A;  1KSL A;  4B3M D;  2E5L D;  1VIO A;  4JI2 D;  4X65 D;  4JI7 D;  1ZE2 A;  3T1Y D;  4DV7 D;  2UXB D;  1KSK A;  4LF5 D;  4LF8 D;  4JI6 D;  1C05 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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