2ISTA

Crystal structure of rlud from e. coli
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
324
structure length
321
Chain Sequence
AQRVQLTATVSENQLGQRLDQALAEMFPDYSRSRIKEWILDQRVLVNGKVCDKPKEKVLGGEQVAINAEIERFEPQDIPLDIVYEDEDIIIINKPRDLVVHPGAGNPDGTVLNALLHYYPPIADVPRAGIVHRLDKDTTGLMVVAKTVPAQTRLVESLQRREITREYEAVAIGHMTAGGTVDEPISRHPTKRTHMAVHPMGKPAVTHYRIMEHFRVHTRLRLRLETGRTHQIRVHMAHITHPLVGDPVYGGRPRPPKGASEAFISTLRKFDRQALHATMLRLYHPISGIEMEWHAPIPQDMVELIEVMRADFEEHKDEVDW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of RluD from E. coli
rcsb
molecule tags Isomerase
source organism Escherichia coli
molecule keywords Ribosomal large subunit pseudouridine synthase D
total genus 86
structure length 321
sequence length 324
ec nomenclature ec 5.4.99.23: 23S rRNA pseudouridine(1911/1915/1917) synthase.
pdb deposition date 2006-10-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00849 PseudoU_synth_2 RNA pseudouridylate synthase
A PF01479 S4 S4 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.290.10 Alpha Beta Roll Structural Genomics Hypothetical 15.5 Kd Protein In mrcA-pckA Intergenic Region; Chain A RNA-binding S4 domain 2istA01
3.30.2350.10 Alpha Beta 2-Layer Sandwich Pseudouridine synthase Pseudouridine synthase 2istA02
1HNXD 4DV4D 5LMND 3UAIA 4LF8D 1ZE1A 4JI2D 1ZE2A 4DUYD 1J5ED 5BR8D 2UUBD 3KBGA 1VIOA 1XMQD 4JI3D 2UXDD 3LWRA 4OUDA 4LF6D 1ZL3A 4X65D 4DR3D 4JV5D 4DR4D 1N34D 3LWQA 2HVYA 4DR1D 3T1YD 4LFAD 4AQYD 3DH3A 4LF4D 1HR0D 1R3FA 1IBKD 3LWVA 2UXBD 4JI6D 4B3SD 1PRZA 1N32D 1FJGD 4DV1D 2UUAD 2UXCD 4X62D 3OTOD 4DV0D 1KSKA 1QYUA 4GKKD 4DUZD 2KTLA 4LF9D 4DR2D 2I82A 1K8WA 4JI7D 4NXND 2UU9D 2AUSA 1JH3A 3HP7A 1KSLA 1C06A 4JI8D 1XPIA 1FKAD 4YHHD 4JI1D 4LF7D 2ISTA 2E5LD 1R3EA 3HAXA 4B3RD 2VQFD 3HJWA 1N36D 4X64D 1N33D 1C05A 2F4VD 2AB4A 2K6PA 1XMOD 4DV3D 4LFCD 3LWPA 4X66D 1V9KA 4JI0D 1KSVA 1DM9A 4DV2D 4JI5D 4DV7D 2EY4A 2JANA 4DV6D 4LFBD 1SGVA 4LABA 3T1HD 1HNZD 4B3TD 3MQKA 4LGTA 4K0KD 1H3FA 2UUCD 4JYAD 1I94D 1XNRD 2VQED 3HJYA 4KHPD 1HNWD 4DR5D 4OX9D 1XNQD 4GKJD 4DV5D 2APOA 1H3EA 4JI4D 2HHHD 4DR7D 4NXMD 1IBMD 4DR6D 5LMUD 4B3MD 2RFKA 3U28A 3LWOA 5IWAD 1IBLD 2ZM6D 4LF5D 1V9FA 1P9KA 4YY3D
chains in the Genus database with same CATH superfamily
1HNXD 4DV4D 5LMND 3UAIA 4LF8D 1SI7A 1ZE1A 4JI2D 1ZE2A 4DUYD 1J5ED 5BR8D 2UUBD 3KBGA 1VIOA 2NVUB 1XMQD 4JI3D 2UXDD 3LWRA 4OUDA 3J80E 4LF6D 3J81E 5KNLA 1ZL3A 4X65D 4DR3D 4JV5D 4DR4D 1N34D 3LWQA 2HVYA 4DR1D 3T1YD 4LFAD 4AQYD 3DH3A 4LF4D 1HR0D 1R3FA 1IBKD 3LWVA 2UXBD 2ZTBA 4JI6D 4B3SD 5IT9E 1PRZA 1N32D 1SB7A 1FJGD 4DV1D 2UUAD 2UXCD 1Y8QB 4X62D 3OTOD 4W5VB 3KYDB 1KSKA 4DV0D 1QYUA 4GKKD 4DUZD 2KTLA 3JAME 5A2QE 4LF9D 3J7AF 4DR2D 1Z2ZA 2I82A 1K8WA 4JI7D 4NXND 2UU9D 2AUSA 1JH3A 3HP7A 1KSLA 1C06A 4JI8D 1XPIA 1Y8XB 1FKAD 1SZWA 4YHHD 4JI1D 4LF7D 2ISTA 2E5LD 1R3EA 3HAXA 4B3RD 2VQFD 3HJWA 1N36D 4X64D 3ONHA 1N33D 1C05A 5FQ2B 2F4VD 2AB4A 2K6PA 1XMOD 4DV3D 4LFCD 4II2A 3LWPA 4X66D 4NNJA 1V9KA 4JI0D 1KSVA 1DM9A 4DV2D 4JI5D 4DV7D 2EY4A 2JANA 4DV6D 2I1SA 4LFBD 1SGVA 5FLXE 4LABA 3FN1A 3T1HD 1HNZD 4B3TD 3MQKA 4LGTA 4K0KD 1H3FA 2UUCD 4JYAD 5LL6S 1I94D 1XNRD 2VQED 3HJYA 4KHPD 1HNWD 3CMMA 4DR5D 4OX9D 1XNQD 4GKJD 4DV5D 2APOA 3ONGA 1H3EA 1Y8RB 4JI4D 2LQ7A 2HHHD 3KYCB 4DR7D 4NXMD 1IBMD 4DR6D 5LMUD 4B3MD 2RFKA 3U28A 4II3A 3LWOA 5IWAD 1IBLD 2ZM6D 4LF5D 1V9FA 1P9KA 4YY3D
chains in the Genus database with same CATH topology
1HNXD 4DV4D 5LMND 3UAIA 4LF8D 1SI7A 1ZE1A 4JI2D 1ZE2A 4DUYD 1J5ED 5BR8D 2UUBD 3KBGA 1VIOA 1XMQD 4JI3D 2UXDD 3LWRA 4OUDA 4LF6D 1ZL3A 4X65D 4DR3D 4JV5D 4DR4D 1N34D 3LWQA 2HVYA 4DR1D 3T1YD 4LFAD 4AQYD 3DH3A 4LF4D 1HR0D 1R3FA 1IBKD 3LWVA 2UXBD 4JI6D 4B3SD 1PRZA 1N32D 1SB7A 1FJGD 4DV1D 2UUAD 2UXCD 4X62D 3OTOD 4DV0D 1KSKA 1QYUA 4GKKD 4DUZD 2KTLA 4LF9D 4DR2D 1Z2ZA 2I82A 1K8WA 4JI7D 4NXND 2UU9D 2AUSA 1JH3A 3HP7A 1KSLA 1C06A 4JI8D 1XPIA 1FKAD 1SZWA 4YHHD 4JI1D 4LF7D 2ISTA 2E5LD 1R3EA 3HAXA 4B3RD 2VQFD 3HJWA 1N36D 4X64D 1N33D 1C05A 2F4VD 2AB4A 2K6PA 1XMOD 4DV3D 4LFCD 3LWPA 4X66D 1V9KA 4JI0D 1KSVA 1DM9A 4DV2D 4JI5D 4DV7D 2EY4A 2JANA 4DV6D 4LFBD 1SGVA 4LABA 3T1HD 1HNZD 4B3TD 3MQKA 4LGTA 4K0KD 1H3FA 2UUCD 4JYAD 1I94D 1XNRD 2VQED 3HJYA 4KHPD 1HNWD 4DR5D 4OX9D 1XNQD 4GKJD 4DV5D 2APOA 1H3EA 4JI4D 2HHHD 4DR7D 4NXMD 1IBMD 4DR6D 5LMUD 4B3MD 2RFKA 3U28A 3LWOA 5IWAD 1IBLD 2ZM6D 4LF5D 1V9FA 1P9KA 4YY3D
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HNX D;  4DV4 D;  5LMN D;  3UAI A;  4LF8 D;  1ZE1 A;  4JI2 D;  1ZE2 A;  4DUY D;  1J5E D;  5BR8 D;  2UUB D;  3KBG A;  1VIO A;  1XMQ D;  4JI3 D;  2UXD D;  3LWR A;  4OUD A;  4LF6 D;  1ZL3 A;  4X65 D;  4DR3 D;  4JV5 D;  4DR4 D;  1N34 D;  3LWQ A;  2HVY A;  4DR1 D;  3T1Y D;  4LFA D;  4AQY D;  3DH3 A;  4LF4 D;  1HR0 D;  1R3F A;  1IBK D;  3LWV A;  2UXB D;  4JI6 D;  4B3S D;  1PRZ A;  1N32 D;  1FJG D;  4DV1 D;  2UUA D;  2UXC D;  4X62 D;  3OTO D;  4DV0 D;  1KSK A;  1QYU A;  4GKK D;  4DUZ D;  2KTL A;  4LF9 D;  4DR2 D;  2I82 A;  1K8W A;  4JI7 D;  4NXN D;  2UU9 D;  2AUS A;  1JH3 A;  3HP7 A;  1KSL A;  1C06 A;  4JI8 D;  1XPI A;  1FKA D;  4YHH D;  4JI1 D;  4LF7 D;  2IST A;  2E5L D;  1R3E A;  3HAX A;  4B3R D;  2VQF D;  3HJW A;  1N36 D;  4X64 D;  1N33 D;  1C05 A;  2F4V D;  2AB4 A;  2K6P A;  1XMO D;  4DV3 D;  4LFC D;  3LWP A;  4X66 D;  1V9K A;  4JI0 D;  1KSV A;  1DM9 A;  4DV2 D;  4JI5 D;  4DV7 D;  2EY4 A;  2JAN A;  4DV6 D;  4LFB D;  1SGV A;  4LAB A;  3T1H D;  1HNZ D;  4B3T D;  3MQK A;  4LGT A;  4K0K D;  1H3F A;  2UUC D;  4JYA D;  1I94 D;  1XNR D;  2VQE D;  3HJY A;  4KHP D;  1HNW D;  4DR5 D;  4OX9 D;  1XNQ D;  4GKJ D;  4DV5 D;  2APO A;  1H3E A;  4JI4 D;  2HHH D;  4DR7 D;  4NXM D;  1IBM D;  4DR6 D;  5LMU D;  4B3M D;  2RFK A;  3U28 A;  3LWO A;  5IWA D;  1IBL D;  2ZM6 D;  4LF5 D;  1V9F A;  1P9K A;  4YY3 D; 
#chains in the Genus database with same CATH topology
 1HNX D;  4DV4 D;  5LMN D;  3UAI A;  4LF8 D;  1SI7 A;  1ZE1 A;  4JI2 D;  1ZE2 A;  4DUY D;  1J5E D;  5BR8 D;  2UUB D;  3KBG A;  1VIO A;  2NVU B;  1XMQ D;  4JI3 D;  2UXD D;  3LWR A;  4OUD A;  3J80 E;  4LF6 D;  3J81 E;  5KNL A;  1ZL3 A;  4X65 D;  4DR3 D;  4JV5 D;  4DR4 D;  1N34 D;  3LWQ A;  2HVY A;  4DR1 D;  3T1Y D;  4LFA D;  4AQY D;  3DH3 A;  4LF4 D;  1HR0 D;  1R3F A;  1IBK D;  3LWV A;  2UXB D;  2ZTB A;  4JI6 D;  4B3S D;  5IT9 E;  1PRZ A;  1N32 D;  1SB7 A;  1FJG D;  4DV1 D;  2UUA D;  2UXC D;  1Y8Q B;  4X62 D;  3OTO D;  4W5V B;  3KYD B;  1KSK A;  4DV0 D;  1QYU A;  4GKK D;  4DUZ D;  2KTL A;  3JAM E;  5A2Q E;  4LF9 D;  3J7A F;  4DR2 D;  1Z2Z A;  2I82 A;  1K8W A;  4JI7 D;  4NXN D;  2UU9 D;  2AUS A;  1JH3 A;  3HP7 A;  1KSL A;  1C06 A;  4JI8 D;  1XPI A;  1Y8X B;  1FKA D;  1SZW A;  4YHH D;  4JI1 D;  4LF7 D;  2IST A;  2E5L D;  1R3E A;  3HAX A;  4B3R D;  2VQF D;  3HJW A;  1N36 D;  4X64 D;  3ONH A;  1N33 D;  1C05 A;  5FQ2 B;  2F4V D;  2AB4 A;  2K6P A;  1XMO D;  4DV3 D;  4LFC D;  4II2 A;  3LWP A;  4X66 D;  4NNJ A;  1V9K A;  4JI0 D;  1KSV A;  1DM9 A;  4DV2 D;  4JI5 D;  4DV7 D;  2EY4 A;  2JAN A;  4DV6 D;  2I1S A;  4LFB D;  1SGV A;  5FLX E;  4LAB A;  3FN1 A;  3T1H D;  1HNZ D;  4B3T D;  3MQK A;  4LGT A;  4K0K D;  1H3F A;  2UUC D;  4JYA D;  5LL6 S;  1I94 D;  1XNR D;  2VQE D;  3HJY A;  4KHP D;  1HNW D;  3CMM A;  4DR5 D;  4OX9 D;  1XNQ D;  4GKJ D;  4DV5 D;  2APO A;  3ONG A;  1H3E A;  1Y8R B;  4JI4 D;  2LQ7 A;  2HHH D;  3KYC B;  4DR7 D;  4NXM D;  1IBM D;  4DR6 D;  5LMU D;  4B3M D;  2RFK A;  3U28 A;  4II3 A;  3LWO A;  5IWA D;  1IBL D;  2ZM6 D;  4LF5 D;  1V9F A;  1P9K A;  4YY3 D; 
#chains in the Genus database with same CATH homology
 1HNX D;  4DV4 D;  5LMN D;  3UAI A;  4LF8 D;  1SI7 A;  1ZE1 A;  4JI2 D;  1ZE2 A;  4DUY D;  1J5E D;  5BR8 D;  2UUB D;  3KBG A;  1VIO A;  1XMQ D;  4JI3 D;  2UXD D;  3LWR A;  4OUD A;  4LF6 D;  1ZL3 A;  4X65 D;  4DR3 D;  4JV5 D;  4DR4 D;  1N34 D;  3LWQ A;  2HVY A;  4DR1 D;  3T1Y D;  4LFA D;  4AQY D;  3DH3 A;  4LF4 D;  1HR0 D;  1R3F A;  1IBK D;  3LWV A;  2UXB D;  4JI6 D;  4B3S D;  1PRZ A;  1N32 D;  1SB7 A;  1FJG D;  4DV1 D;  2UUA D;  2UXC D;  4X62 D;  3OTO D;  4DV0 D;  1KSK A;  1QYU A;  4GKK D;  4DUZ D;  2KTL A;  4LF9 D;  4DR2 D;  1Z2Z A;  2I82 A;  1K8W A;  4JI7 D;  4NXN D;  2UU9 D;  2AUS A;  1JH3 A;  3HP7 A;  1KSL A;  1C06 A;  4JI8 D;  1XPI A;  1FKA D;  1SZW A;  4YHH D;  4JI1 D;  4LF7 D;  2IST A;  2E5L D;  1R3E A;  3HAX A;  4B3R D;  2VQF D;  3HJW A;  1N36 D;  4X64 D;  1N33 D;  1C05 A;  2F4V D;  2AB4 A;  2K6P A;  1XMO D;  4DV3 D;  4LFC D;  3LWP A;  4X66 D;  1V9K A;  4JI0 D;  1KSV A;  1DM9 A;  4DV2 D;  4JI5 D;  4DV7 D;  2EY4 A;  2JAN A;  4DV6 D;  4LFB D;  1SGV A;  4LAB A;  3T1H D;  1HNZ D;  4B3T D;  3MQK A;  4LGT A;  4K0K D;  1H3F A;  2UUC D;  4JYA D;  1I94 D;  1XNR D;  2VQE D;  3HJY A;  4KHP D;  1HNW D;  4DR5 D;  4OX9 D;  1XNQ D;  4GKJ D;  4DV5 D;  2APO A;  1H3E A;  4JI4 D;  2HHH D;  4DR7 D;  4NXM D;  1IBM D;  4DR6 D;  5LMU D;  4B3M D;  2RFK A;  3U28 A;  3LWO A;  5IWA D;  1IBL D;  2ZM6 D;  4LF5 D;  1V9F A;  1P9K A;  4YY3 D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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