2IUCB

Structure of alkaline phosphatase from the antarctic bacterium tab5
Total Genus 125
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
125
Knots found
sequence length
346
structure length
342
Chain Sequence
QLKTPKNVILLISDGAGLSQISSTFYFKSGTPNYTQFKNIGLIKTSSSREDVTDSASGATAFSCGIKTYNAAIGVADDSTAVKSIVEIAALNSIKTGVVATSSITHATPASFYAHALNRGLEEEIAMDMTESDLDFFAGGGLNYFTSRSDSKDVLAILKGNQFTINTTGLTDFSSIASNRKMGFLLADEAMPTMEKGRGNFLSAATDLAIQFLSKDNSAFFIMSEGSQIDWGGHANNASYLISEINDFDDAIGTALAFAKSDGNTLVIVTSDHETGGFTLAAKSNKSEYSDYTEIGPTFSTGGHSATLIPVFAYGPGSEEFIGIYENNEIFHKILKVTKWNQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords ALKALINE PHOSPHATASE
publication title Crystal Structure of Alkaline Phosphatase from the Antarctic Bacterium Tab5.
pubmed doi rcsb
source organism Antarctic bacterium tab5
molecule tags Hydrolase
total genus 125
structure length 342
sequence length 346
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2006-06-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 2iucB00
1KHJA 2X98A 4LRCA 4CXSA 3WAYA 4CXKA 1EI6A 3UN3A 4GTWA 1AJCA 2GA3A 3UO0A 1Y7AA 3ED4A 2W5TA 5IJSA 5L0BA 2ANHA 1KH5A 1ZEBA 3WAVA 3NKNA 3UN5A 1URBA 2W8DA 1KHKA 3KD8A 3WAWA 1ED8A 4MY4A 4UPKA 4KJGA 4CYSA 1ALIA 2W5XA 1K7HA 3IGZB 4NWJA 4LR7A 3MK2A 3MK1A 3SZZA 4LREA 4UPHA 2XRGA 4KM4A 1AJDA 1ED9A 2IUCA 3BDFA 3NKMA 5GOVA 3T02A 3IDDA 3B5QA 1B8JA 3BDGA 1URAA 1EW8A 2GSUA 2IFYA 1AJBA 4B56A 1HJKA 3SZYA 5EGHA 1ANIA 2G9YA 1O98A 4ZGAA 1ELZA 1Y6VA 5LQQA 1FSUA 1N2LA 3NKRA 1KH7A 1O99A 2W5QA 4MHXA 4N7TA 5AJ9A 1E1ZP 3DYCA 3WBHA 1E33P 3NKPA 4KAVA 4CYRA 3M8ZA 5TJ3A 4LR8A 4NWXA 3T00A 2GSOA 4UOPA 2IUCB 3CMRA 4KJDA 4LR2A 3E2DA 3BDGB 5L0EA 3TX0A 1AUKA 1E3CP 1SHNA 2QZUA 2XR9A 3TWZA 1KHNA 4GTYA 2ZKTA 5DLWA 3OT9A 1HQAA 4QAXA 5HRTA 1E2SP 3LXQA 5DLVA 1EW2A 5EGEA 4LRBA 1HDHA 5L0KA 1P49A 4FDIA 5K4PA 1ELXA 1SHQA 2GSNA 5C66A 2D1GA 4GTZA 4MIVA 4LRFA 2VQRA 4UOOA 4TN0A 4LR9A 2GLQA 3M8YA 1N2KA 1KHLA 4ZG6A 4CXUA 5KXAA 5GRRA 1KH9A 4LRDA 5LRNA 1ALHA 1ELYA 4LRAA 4ZG7A 3MK0A 1ALJA 5LIAA 3NKOA 1EJJA 3M8WA 2W5WA 3IGYB 3UN2A 4ZG9A 4UORA 2W5VA 1ZEFA 1ZEDA 2W5RA 4UPLA 1ANJA 3Q3QA 4UPIA 5INHA 4KAYA 5IJQA 3T01A 1AJAA 5DLTA 2W5SA 1ALKA 2W8SA 5LRMA 3WAXA 1EQJA 4YR1A 1EW9A 3BDHA 3TG0A 4LQYA 4FDJA 3NKQA 3DPCA 1KH4A 3UNYA 4GTXA 3A52A 2RH6A 3M7VA 3NVLA
chains in the Genus database with same CATH superfamily
1KHJA 2X98A 4LRCA 4CXSA 3WAYA 4CXKA 1EI6A 3UN3A 4GTWA 1AJCA 2GA3A 3UO0A 1Y7AA 3ED4A 2W5TA 5IJSA 5L0BA 2ANHA 1KH5A 1ZEBA 3WAVA 3NKNA 3UN5A 1URBA 2W8DA 1KHKA 3KD8A 3WAWA 1ED8A 4MY4A 4UPKA 4KJGA 4CYSA 1ALIA 2W5XA 1K7HA 3IGZB 4NWJA 4LR7A 3MK2A 3MK1A 3SZZA 4LREA 4UPHA 2XRGA 4KM4A 1AJDA 1ED9A 2IUCA 3BDFA 3NKMA 5GOVA 3T02A 3IDDA 3B5QA 1B8JA 3BDGA 1URAA 1EW8A 2GSUA 2IFYA 1AJBA 4B56A 1HJKA 3SZYA 5EGHA 1ANIA 2G9YA 1O98A 4ZGAA 1ELZA 1Y6VA 5LQQA 1FSUA 1N2LA 3NKRA 1KH7A 1O99A 2W5QA 4MHXA 4N7TA 5AJ9A 1E1ZP 3DYCA 3WBHA 1E33P 3NKPA 4KAVA 4CYRA 3M8ZA 5TJ3A 4LR8A 4NWXA 3T00A 2GSOA 4UOPA 2IUCB 3CMRA 4KJDA 4LR2A 3E2DA 3BDGB 5L0EA 3TX0A 1AUKA 1E3CP 1SHNA 2QZUA 2XR9A 3TWZA 1KHNA 4GTYA 2ZKTA 5DLWA 3OT9A 1HQAA 4QAXA 5HRTA 1E2SP 3LXQA 5DLVA 1EW2A 5EGEA 4LRBA 1HDHA 5L0KA 1P49A 4FDIA 5K4PA 1ELXA 1SHQA 2GSNA 5C66A 2D1GA 4GTZA 4MIVA 4LRFA 2VQRA 4UOOA 4TN0A 4LR9A 2GLQA 3M8YA 1N2KA 1KHLA 4ZG6A 4CXUA 5KXAA 5GRRA 1KH9A 4LRDA 5LRNA 1ALHA 1ELYA 4LRAA 4ZG7A 3MK0A 1ALJA 5LIAA 3NKOA 1EJJA 3M8WA 2W5WA 3IGYB 3UN2A 4ZG9A 4UORA 2W5VA 1ZEFA 1ZEDA 2W5RA 4UPLA 1ANJA 3Q3QA 4UPIA 5INHA 4KAYA 5IJQA 3T01A 1AJAA 5DLTA 2W5SA 1ALKA 2W8SA 5LRMA 3WAXA 1EQJA 4YR1A 1EW9A 3BDHA 3TG0A 4LQYA 4FDJA 3NKQA 3DPCA 1KH4A 3UNYA 4GTXA 3A52A 2RH6A 3M7VA 3NVLA
chains in the Genus database with same CATH topology
1KHJA 2X98A 4LRCA 4CXSA 3WAYA 4CXKA 1EI6A 3UN3A 4GTWA 1AJCA 2GA3A 3UO0A 1Y7AA 3ED4A 2W5TA 5IJSA 5L0BA 2ANHA 1KH5A 1ZEBA 3WAVA 3NKNA 3UN5A 1URBA 2W8DA 1KHKA 3KD8A 3WAWA 1ED8A 4MY4A 4UPKA 4KJGA 4CYSA 1ALIA 2W5XA 1K7HA 3IGZB 4NWJA 4LR7A 3MK2A 3MK1A 3SZZA 4LREA 4UPHA 2XRGA 4KM4A 1AJDA 1ED9A 2IUCA 3BDFA 3NKMA 5GOVA 3T02A 3IDDA 3B5QA 1B8JA 3BDGA 1URAA 1EW8A 2GSUA 2IFYA 1AJBA 4B56A 1HJKA 3SZYA 5EGHA 1ANIA 2G9YA 1O98A 4ZGAA 1ELZA 1Y6VA 5LQQA 1FSUA 1N2LA 3NKRA 1KH7A 1O99A 2W5QA 4MHXA 4N7TA 5AJ9A 1E1ZP 3DYCA 3WBHA 1E33P 3NKPA 4KAVA 4CYRA 3M8ZA 5TJ3A 4LR8A 4NWXA 3T00A 2GSOA 4UOPA 2IUCB 3CMRA 4KJDA 4LR2A 3E2DA 3BDGB 5L0EA 3TX0A 1AUKA 1E3CP 1SHNA 2QZUA 2XR9A 3TWZA 1KHNA 4GTYA 2ZKTA 5DLWA 3OT9A 1HQAA 4QAXA 5HRTA 1E2SP 3LXQA 5DLVA 1EW2A 5EGEA 4LRBA 1HDHA 5L0KA 1P49A 4FDIA 5K4PA 1ELXA 1SHQA 2GSNA 5C66A 2D1GA 4GTZA 4MIVA 4LRFA 2VQRA 4UOOA 4TN0A 4LR9A 2GLQA 3M8YA 1N2KA 1KHLA 4ZG6A 4CXUA 5KXAA 5GRRA 1KH9A 4LRDA 5LRNA 1ALHA 1ELYA 4LRAA 4ZG7A 3MK0A 1ALJA 5LIAA 3NKOA 1EJJA 3M8WA 2W5WA 3IGYB 3UN2A 4ZG9A 4UORA 2W5VA 1ZEFA 1ZEDA 2W5RA 4UPLA 1ANJA 3Q3QA 4UPIA 5INHA 4KAYA 5IJQA 3T01A 1AJAA 5DLTA 2W5SA 1ALKA 2W8SA 5LRMA 3WAXA 1EQJA 4YR1A 1EW9A 3BDHA 3TG0A 4LQYA 4FDJA 3NKQA 3DPCA 1KH4A 3UNYA 4GTXA 3A52A 2RH6A 3M7VA 3NVLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KHJ A;  2X98 A;  4LRC A;  4CXS A;  3WAY A;  4CXK A;  1EI6 A;  3UN3 A;  4GTW A;  1AJC A;  2GA3 A;  3UO0 A;  1Y7A A;  3ED4 A;  2W5T A;  5IJS A;  5L0B A;  2ANH A;  1KH5 A;  1ZEB A;  3WAV A;  3NKN A;  3UN5 A;  1URB A;  2W8D A;  1KHK A;  3KD8 A;  3WAW A;  1ED8 A;  4MY4 A;  4UPK A;  4KJG A;  4CYS A;  1ALI A;  2W5X A;  1K7H A;  3IGZ B;  4NWJ A;  4LR7 A;  3MK2 A;  3MK1 A;  3SZZ A;  4LRE A;  4UPH A;  2XRG A;  4KM4 A;  1AJD A;  1ED9 A;  2IUC A;  3BDF A;  3NKM A;  5GOV A;  3T02 A;  3IDD A;  3B5Q A;  1B8J A;  3BDG A;  1URA A;  1EW8 A;  2GSU A;  2IFY A;  1AJB A;  4B56 A;  1HJK A;  3SZY A;  5EGH A;  1ANI A;  2G9Y A;  1O98 A;  4ZGA A;  1ELZ A;  1Y6V A;  5LQQ A;  1FSU A;  1N2L A;  3NKR A;  1KH7 A;  1O99 A;  2W5Q A;  4MHX A;  4N7T A;  5AJ9 A;  1E1Z P;  3DYC A;  3WBH A;  1E33 P;  3NKP A;  4KAV A;  4CYR A;  3M8Z A;  5TJ3 A;  4LR8 A;  4NWX A;  3T00 A;  2GSO A;  4UOP A;  2IUC B;  3CMR A;  4KJD A;  4LR2 A;  3E2D A;  3BDG B;  5L0E A;  3TX0 A;  1AUK A;  1E3C P;  1SHN A;  2QZU A;  2XR9 A;  3TWZ A;  1KHN A;  4GTY A;  2ZKT A;  5DLW A;  3OT9 A;  1HQA A;  4QAX A;  5HRT A;  1E2S P;  3LXQ A;  5DLV A;  1EW2 A;  5EGE A;  4LRB A;  1HDH A;  5L0K A;  1P49 A;  4FDI A;  5K4P A;  1ELX A;  1SHQ A;  2GSN A;  5C66 A;  2D1G A;  4GTZ A;  4MIV A;  4LRF A;  2VQR A;  4UOO A;  4TN0 A;  4LR9 A;  2GLQ A;  3M8Y A;  1N2K A;  1KHL A;  4ZG6 A;  4CXU A;  5KXA A;  5GRR A;  1KH9 A;  4LRD A;  5LRN A;  1ALH A;  1ELY A;  4LRA A;  4ZG7 A;  3MK0 A;  1ALJ A;  5LIA A;  3NKO A;  1EJJ A;  3M8W A;  2W5W A;  3IGY B;  3UN2 A;  4ZG9 A;  4UOR A;  2W5V A;  1ZEF A;  1ZED A;  2W5R A;  4UPL A;  1ANJ A;  3Q3Q A;  4UPI A;  5INH A;  4KAY A;  5IJQ A;  3T01 A;  1AJA A;  5DLT A;  2W5S A;  1ALK A;  2W8S A;  5LRM A;  3WAX A;  1EQJ A;  4YR1 A;  1EW9 A;  3BDH A;  3TG0 A;  4LQY A;  4FDJ A;  3NKQ A;  3DPC A;  1KH4 A;  3UNY A;  4GTX A;  3A52 A;  2RH6 A;  3M7V A;  3NVL A; 
#chains in the Genus database with same CATH topology
 1KHJ A;  2X98 A;  4LRC A;  4CXS A;  3WAY A;  4CXK A;  1EI6 A;  3UN3 A;  4GTW A;  1AJC A;  2GA3 A;  3UO0 A;  1Y7A A;  3ED4 A;  2W5T A;  5IJS A;  5L0B A;  2ANH A;  1KH5 A;  1ZEB A;  3WAV A;  3NKN A;  3UN5 A;  1URB A;  2W8D A;  1KHK A;  3KD8 A;  3WAW A;  1ED8 A;  4MY4 A;  4UPK A;  4KJG A;  4CYS A;  1ALI A;  2W5X A;  1K7H A;  3IGZ B;  4NWJ A;  4LR7 A;  3MK2 A;  3MK1 A;  3SZZ A;  4LRE A;  4UPH A;  2XRG A;  4KM4 A;  1AJD A;  1ED9 A;  2IUC A;  3BDF A;  3NKM A;  5GOV A;  3T02 A;  3IDD A;  3B5Q A;  1B8J A;  3BDG A;  1URA A;  1EW8 A;  2GSU A;  2IFY A;  1AJB A;  4B56 A;  1HJK A;  3SZY A;  5EGH A;  1ANI A;  2G9Y A;  1O98 A;  4ZGA A;  1ELZ A;  1Y6V A;  5LQQ A;  1FSU A;  1N2L A;  3NKR A;  1KH7 A;  1O99 A;  2W5Q A;  4MHX A;  4N7T A;  5AJ9 A;  1E1Z P;  3DYC A;  3WBH A;  1E33 P;  3NKP A;  4KAV A;  4CYR A;  3M8Z A;  5TJ3 A;  4LR8 A;  4NWX A;  3T00 A;  2GSO A;  4UOP A;  2IUC B;  3CMR A;  4KJD A;  4LR2 A;  3E2D A;  3BDG B;  5L0E A;  3TX0 A;  1AUK A;  1E3C P;  1SHN A;  2QZU A;  2XR9 A;  3TWZ A;  1KHN A;  4GTY A;  2ZKT A;  5DLW A;  3OT9 A;  1HQA A;  4QAX A;  5HRT A;  1E2S P;  3LXQ A;  5DLV A;  1EW2 A;  5EGE A;  4LRB A;  1HDH A;  5L0K A;  1P49 A;  4FDI A;  5K4P A;  1ELX A;  1SHQ A;  2GSN A;  5C66 A;  2D1G A;  4GTZ A;  4MIV A;  4LRF A;  2VQR A;  4UOO A;  4TN0 A;  4LR9 A;  2GLQ A;  3M8Y A;  1N2K A;  1KHL A;  4ZG6 A;  4CXU A;  5KXA A;  5GRR A;  1KH9 A;  4LRD A;  5LRN A;  1ALH A;  1ELY A;  4LRA A;  4ZG7 A;  3MK0 A;  1ALJ A;  5LIA A;  3NKO A;  1EJJ A;  3M8W A;  2W5W A;  3IGY B;  3UN2 A;  4ZG9 A;  4UOR A;  2W5V A;  1ZEF A;  1ZED A;  2W5R A;  4UPL A;  1ANJ A;  3Q3Q A;  4UPI A;  5INH A;  4KAY A;  5IJQ A;  3T01 A;  1AJA A;  5DLT A;  2W5S A;  1ALK A;  2W8S A;  5LRM A;  3WAX A;  1EQJ A;  4YR1 A;  1EW9 A;  3BDH A;  3TG0 A;  4LQY A;  4FDJ A;  3NKQ A;  3DPC A;  1KH4 A;  3UNY A;  4GTX A;  3A52 A;  2RH6 A;  3M7V A;  3NVL A; 
#chains in the Genus database with same CATH homology
 1KHJ A;  2X98 A;  4LRC A;  4CXS A;  3WAY A;  4CXK A;  1EI6 A;  3UN3 A;  4GTW A;  1AJC A;  2GA3 A;  3UO0 A;  1Y7A A;  3ED4 A;  2W5T A;  5IJS A;  5L0B A;  2ANH A;  1KH5 A;  1ZEB A;  3WAV A;  3NKN A;  3UN5 A;  1URB A;  2W8D A;  1KHK A;  3KD8 A;  3WAW A;  1ED8 A;  4MY4 A;  4UPK A;  4KJG A;  4CYS A;  1ALI A;  2W5X A;  1K7H A;  3IGZ B;  4NWJ A;  4LR7 A;  3MK2 A;  3MK1 A;  3SZZ A;  4LRE A;  4UPH A;  2XRG A;  4KM4 A;  1AJD A;  1ED9 A;  2IUC A;  3BDF A;  3NKM A;  5GOV A;  3T02 A;  3IDD A;  3B5Q A;  1B8J A;  3BDG A;  1URA A;  1EW8 A;  2GSU A;  2IFY A;  1AJB A;  4B56 A;  1HJK A;  3SZY A;  5EGH A;  1ANI A;  2G9Y A;  1O98 A;  4ZGA A;  1ELZ A;  1Y6V A;  5LQQ A;  1FSU A;  1N2L A;  3NKR A;  1KH7 A;  1O99 A;  2W5Q A;  4MHX A;  4N7T A;  5AJ9 A;  1E1Z P;  3DYC A;  3WBH A;  1E33 P;  3NKP A;  4KAV A;  4CYR A;  3M8Z A;  5TJ3 A;  4LR8 A;  4NWX A;  3T00 A;  2GSO A;  4UOP A;  2IUC B;  3CMR A;  4KJD A;  4LR2 A;  3E2D A;  3BDG B;  5L0E A;  3TX0 A;  1AUK A;  1E3C P;  1SHN A;  2QZU A;  2XR9 A;  3TWZ A;  1KHN A;  4GTY A;  2ZKT A;  5DLW A;  3OT9 A;  1HQA A;  4QAX A;  5HRT A;  1E2S P;  3LXQ A;  5DLV A;  1EW2 A;  5EGE A;  4LRB A;  1HDH A;  5L0K A;  1P49 A;  4FDI A;  5K4P A;  1ELX A;  1SHQ A;  2GSN A;  5C66 A;  2D1G A;  4GTZ A;  4MIV A;  4LRF A;  2VQR A;  4UOO A;  4TN0 A;  4LR9 A;  2GLQ A;  3M8Y A;  1N2K A;  1KHL A;  4ZG6 A;  4CXU A;  5KXA A;  5GRR A;  1KH9 A;  4LRD A;  5LRN A;  1ALH A;  1ELY A;  4LRA A;  4ZG7 A;  3MK0 A;  1ALJ A;  5LIA A;  3NKO A;  1EJJ A;  3M8W A;  2W5W A;  3IGY B;  3UN2 A;  4ZG9 A;  4UOR A;  2W5V A;  1ZEF A;  1ZED A;  2W5R A;  4UPL A;  1ANJ A;  3Q3Q A;  4UPI A;  5INH A;  4KAY A;  5IJQ A;  3T01 A;  1AJA A;  5DLT A;  2W5S A;  1ALK A;  2W8S A;  5LRM A;  3WAX A;  1EQJ A;  4YR1 A;  1EW9 A;  3BDH A;  3TG0 A;  4LQY A;  4FDJ A;  3NKQ A;  3DPC A;  1KH4 A;  3UNY A;  4GTX A;  3A52 A;  2RH6 A;  3M7V A;  3NVL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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