2IUCB

Structure of alkaline phosphatase from the antarctic bacterium tab5
Total Genus 125
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
125
Knots found
sequence length
346
structure length
342
Chain Sequence
b'QLKTPKNVILLISDGAGLSQISSTFYFKSGTPNYTQFKNIGLIKTSSSREDVTDSASGATAFSCGIKTYNAAIGVADDSTAVKSIVEIAALNSIKTGVVATSSITHATPASFYAHALNRGLEEEIAMDMTESDLDFFAGGGLNYFTSRSDSKDVLAILKGNQFTINTTGLTDFSSIASNRKMGFLLADEAMPTMEKGRGNFLSAATDLAIQFLSKDNSAFFIMSEGSQIDWGGHANNASYLISEINDFDDAIGTALAFAKSDGNTLVIVTSDHETGGFTLAAKSNKSEYSDYTEIGPTFSTGGHSATLIPVFAYGPGSEEFIGIYENNEIFHKILKVTKWNQ'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords ALKALINE PHOSPHATASE
publication title Crystal Structure of Alkaline Phosphatase from the Antarctic Bacterium Tab5.
pubmed doi rcsb
source organism Antarctic bacterium tab5
molecule tags Hydrolase
total genus 125
structure length 342
sequence length 346
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2006-06-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 2iucB00
2ANHA 1URAA 4MY4A 1HQAA 1KHJA 2W5QA 1SHNA 4UORA 5DLWA 2QZUA 2ZKTA 4GTWA 3WAXA 4LRFA 1ALKA 1O99A 2G9YA 5L0EA 3A52A 3T01A 3Q3QA 4ZGAA 4GTXA 1KH7A 4LR8A 3TG0A 3UN3A 1O98A 4CXKA 3NKNA 2W5SA 3NKMA 4LRDA 1KHNA 2W8DA 3M8WA 3WAVA 3IDDA 1B8JA 5L0BA 1KH5A 1KHLA 3UN2A 1ED9A 1Y7AA 3LXQA 1KH9A 2W8SA 1K7HA 2VQRA 2XRGA 5C66A 1ELZA 1HDHA 4N7TA 1ZEBA 5K4PA 1AJDA 4KAVA 1ANIA 1ELYA 1ELXA 1AJAA 4CYSA 3CMRA 4NWXA 4FDIA 3DYCA 4LRBA 5LRMA 4UOOA 1FSUA 3BDFA 4UPHA 1Y6VA 5LQQA 5EGEA 4CYRA 4ZG6A 3ED4A 3E2DA 5LIAA 3DPCA 4GTZA 5AJ9A 3T02A 4YR1A 1N2LA 4ZG7A 1ZEFA 1ALIA 1ED8A 1EQJA 2GSNA 2IFYA 2RH6A 2W5WA 1KHKA 5GRRA 3M8ZA 3BDGA 3NKOA 3NVLA 4LR7A 3BDGB 4QAXA 2W5XA 4LRCA 1E3CP 2GA3A 3WBHA 4TN0A 1URBA 2IUCB 4UPLA 3SZZA 2XR9A 1EI6A 4LR2A 4B56A 3NKPA 4NWJA 4CXUA 3TWZA 5TJ3A 4GTYA 4LQYA 1EW8A 1HJKA 4KM4A 3SZYA 1EW9A 5EGHA 4ZG9A 3M7VA 5INHA 5IJQA 3BDHA 3NKQA 3T00A 5HRTA 4FDJA 1AJCA 1ZEDA 4LR9A 5GOVA 3KD8A 5L0KA 1E2SP 4UOPA 5LRNA 1ALHA 2X98A 2D1GA 2GLQA 2W5TA 1ALJA 4KJDA 4CXSA 1ANJA 1E33P 3UNYA 4KAYA 4LREA 5KXAA 1KH4A 5DLTA 4UPKA 2W5RA 1SHQA 1EJJA 2IUCA 3IGZB 1AUKA 2GSOA 2GSUA 3B5QA 3WAWA 4KJGA 1EW2A 5DLVA 3MK2A 1E1ZP 3IGYB 3M8YA 3NKRA 4MIVA 4LRAA 1AJBA 4UPIA 3UO0A 4MHXA 3MK0A 3OT9A 3WAYA 5IJSA 1N2KA 3MK1A 3TX0A 1P49A 2W5VA 3UN5A
chains in the Genus database with same CATH superfamily
2ANHA 1URAA 4MY4A 1HQAA 1KHJA 2W5QA 1SHNA 4UORA 5DLWA 2QZUA 2ZKTA 4GTWA 3WAXA 4LRFA 1ALKA 1O99A 2G9YA 5L0EA 3A52A 3T01A 3Q3QA 4ZGAA 4GTXA 1KH7A 4LR8A 3TG0A 3UN3A 1O98A 4CXKA 3NKNA 2W5SA 3NKMA 4LRDA 1KHNA 2W8DA 3M8WA 3WAVA 3IDDA 1B8JA 5L0BA 1KH5A 1KHLA 3UN2A 1ED9A 1Y7AA 3LXQA 1KH9A 2W8SA 1K7HA 2VQRA 2XRGA 5C66A 1ELZA 1HDHA 4N7TA 1ZEBA 5K4PA 1AJDA 4KAVA 1ANIA 1ELYA 1ELXA 1AJAA 4CYSA 3CMRA 4NWXA 4FDIA 3DYCA 4LRBA 5LRMA 4UOOA 1FSUA 3BDFA 4UPHA 1Y6VA 5LQQA 5EGEA 4CYRA 4ZG6A 3ED4A 3E2DA 5LIAA 3DPCA 4GTZA 5AJ9A 3T02A 4YR1A 1N2LA 4ZG7A 1ZEFA 1ALIA 1ED8A 1EQJA 2GSNA 2IFYA 2RH6A 2W5WA 1KHKA 5GRRA 3M8ZA 3BDGA 3NKOA 3NVLA 4LR7A 3BDGB 4QAXA 2W5XA 4LRCA 1E3CP 2GA3A 3WBHA 4TN0A 1URBA 2IUCB 4UPLA 3SZZA 2XR9A 1EI6A 4LR2A 4B56A 3NKPA 4NWJA 4CXUA 3TWZA 5TJ3A 4GTYA 4LQYA 1EW8A 1HJKA 4KM4A 3SZYA 1EW9A 5EGHA 4ZG9A 3M7VA 5INHA 5IJQA 3BDHA 3NKQA 3T00A 5HRTA 4FDJA 1AJCA 1ZEDA 4LR9A 5GOVA 3KD8A 5L0KA 1E2SP 4UOPA 5LRNA 1ALHA 2X98A 2D1GA 2GLQA 2W5TA 1ALJA 4KJDA 4CXSA 1ANJA 1E33P 3UNYA 4KAYA 4LREA 5KXAA 1KH4A 5DLTA 4UPKA 2W5RA 1SHQA 1EJJA 2IUCA 3IGZB 1AUKA 2GSOA 2GSUA 3B5QA 3WAWA 4KJGA 1EW2A 5DLVA 3MK2A 1E1ZP 3IGYB 3M8YA 3NKRA 4MIVA 4LRAA 1AJBA 4UPIA 3UO0A 4MHXA 3MK0A 3OT9A 3WAYA 5IJSA 1N2KA 3MK1A 3TX0A 1P49A 2W5VA 3UN5A
chains in the Genus database with same CATH topology
2ANHA 1URAA 4MY4A 1HQAA 1KHJA 2W5QA 1SHNA 4UORA 5DLWA 2QZUA 2ZKTA 4GTWA 3WAXA 4LRFA 1ALKA 1O99A 2G9YA 5L0EA 3A52A 3T01A 3Q3QA 4ZGAA 4GTXA 1KH7A 4LR8A 3TG0A 3UN3A 1O98A 4CXKA 3NKNA 2W5SA 3NKMA 4LRDA 1KHNA 2W8DA 3M8WA 3WAVA 3IDDA 1B8JA 5L0BA 1KH5A 1KHLA 3UN2A 1ED9A 1Y7AA 3LXQA 1KH9A 2W8SA 1K7HA 2VQRA 2XRGA 5C66A 1ELZA 1HDHA 4N7TA 1ZEBA 5K4PA 1AJDA 4KAVA 1ANIA 1ELYA 1ELXA 1AJAA 4CYSA 3CMRA 4NWXA 4FDIA 3DYCA 4LRBA 5LRMA 4UOOA 1FSUA 3BDFA 4UPHA 1Y6VA 5LQQA 5EGEA 4CYRA 4ZG6A 3ED4A 3E2DA 5LIAA 3DPCA 4GTZA 5AJ9A 3T02A 4YR1A 1N2LA 4ZG7A 1ZEFA 1ALIA 1ED8A 1EQJA 2GSNA 2IFYA 2RH6A 2W5WA 1KHKA 5GRRA 3M8ZA 3BDGA 3NKOA 3NVLA 4LR7A 3BDGB 4QAXA 2W5XA 4LRCA 1E3CP 2GA3A 3WBHA 4TN0A 1URBA 2IUCB 4UPLA 3SZZA 2XR9A 1EI6A 4LR2A 4B56A 3NKPA 4NWJA 4CXUA 3TWZA 5TJ3A 4GTYA 4LQYA 1EW8A 1HJKA 4KM4A 3SZYA 1EW9A 5EGHA 4ZG9A 3M7VA 5INHA 5IJQA 3BDHA 3NKQA 3T00A 5HRTA 4FDJA 1AJCA 1ZEDA 4LR9A 5GOVA 3KD8A 5L0KA 1E2SP 4UOPA 5LRNA 1ALHA 2X98A 2D1GA 2GLQA 2W5TA 1ALJA 4KJDA 4CXSA 1ANJA 1E33P 3UNYA 4KAYA 4LREA 5KXAA 1KH4A 5DLTA 4UPKA 2W5RA 1SHQA 1EJJA 2IUCA 3IGZB 1AUKA 2GSOA 2GSUA 3B5QA 3WAWA 4KJGA 1EW2A 5DLVA 3MK2A 1E1ZP 3IGYB 3M8YA 3NKRA 4MIVA 4LRAA 1AJBA 4UPIA 3UO0A 4MHXA 3MK0A 3OT9A 3WAYA 5IJSA 1N2KA 3MK1A 3TX0A 1P49A 2W5VA 3UN5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ANH A;  1URA A;  4MY4 A;  1HQA A;  1KHJ A;  2W5Q A;  1SHN A;  4UOR A;  5DLW A;  2QZU A;  2ZKT A;  4GTW A;  3WAX A;  4LRF A;  1ALK A;  1O99 A;  2G9Y A;  5L0E A;  3A52 A;  3T01 A;  3Q3Q A;  4ZGA A;  4GTX A;  1KH7 A;  4LR8 A;  3TG0 A;  3UN3 A;  1O98 A;  4CXK A;  3NKN A;  2W5S A;  3NKM A;  4LRD A;  1KHN A;  2W8D A;  3M8W A;  3WAV A;  3IDD A;  1B8J A;  5L0B A;  1KH5 A;  1KHL A;  3UN2 A;  1ED9 A;  1Y7A A;  3LXQ A;  1KH9 A;  2W8S A;  1K7H A;  2VQR A;  2XRG A;  5C66 A;  1ELZ A;  1HDH A;  4N7T A;  1ZEB A;  5K4P A;  1AJD A;  4KAV A;  1ANI A;  1ELY A;  1ELX A;  1AJA A;  4CYS A;  3CMR A;  4NWX A;  4FDI A;  3DYC A;  4LRB A;  5LRM A;  4UOO A;  1FSU A;  3BDF A;  4UPH A;  1Y6V A;  5LQQ A;  5EGE A;  4CYR A;  4ZG6 A;  3ED4 A;  3E2D A;  5LIA A;  3DPC A;  4GTZ A;  5AJ9 A;  3T02 A;  4YR1 A;  1N2L A;  4ZG7 A;  1ZEF A;  1ALI A;  1ED8 A;  1EQJ A;  2GSN A;  2IFY A;  2RH6 A;  2W5W A;  1KHK A;  5GRR A;  3M8Z A;  3BDG A;  3NKO A;  3NVL A;  4LR7 A;  3BDG B;  4QAX A;  2W5X A;  4LRC A;  1E3C P;  2GA3 A;  3WBH A;  4TN0 A;  1URB A;  2IUC B;  4UPL A;  3SZZ A;  2XR9 A;  1EI6 A;  4LR2 A;  4B56 A;  3NKP A;  4NWJ A;  4CXU A;  3TWZ A;  5TJ3 A;  4GTY A;  4LQY A;  1EW8 A;  1HJK A;  4KM4 A;  3SZY A;  1EW9 A;  5EGH A;  4ZG9 A;  3M7V A;  5INH A;  5IJQ A;  3BDH A;  3NKQ A;  3T00 A;  5HRT A;  4FDJ A;  1AJC A;  1ZED A;  4LR9 A;  5GOV A;  3KD8 A;  5L0K A;  1E2S P;  4UOP A;  5LRN A;  1ALH A;  2X98 A;  2D1G A;  2GLQ A;  2W5T A;  1ALJ A;  4KJD A;  4CXS A;  1ANJ A;  1E33 P;  3UNY A;  4KAY A;  4LRE A;  5KXA A;  1KH4 A;  5DLT A;  4UPK A;  2W5R A;  1SHQ A;  1EJJ A;  2IUC A;  3IGZ B;  1AUK A;  2GSO A;  2GSU A;  3B5Q A;  3WAW A;  4KJG A;  1EW2 A;  5DLV A;  3MK2 A;  1E1Z P;  3IGY B;  3M8Y A;  3NKR A;  4MIV A;  4LRA A;  1AJB A;  4UPI A;  3UO0 A;  4MHX A;  3MK0 A;  3OT9 A;  3WAY A;  5IJS A;  1N2K A;  3MK1 A;  3TX0 A;  1P49 A;  2W5V A;  3UN5 A; 
#chains in the Genus database with same CATH topology
 2ANH A;  1URA A;  4MY4 A;  1HQA A;  1KHJ A;  2W5Q A;  1SHN A;  4UOR A;  5DLW A;  2QZU A;  2ZKT A;  4GTW A;  3WAX A;  4LRF A;  1ALK A;  1O99 A;  2G9Y A;  5L0E A;  3A52 A;  3T01 A;  3Q3Q A;  4ZGA A;  4GTX A;  1KH7 A;  4LR8 A;  3TG0 A;  3UN3 A;  1O98 A;  4CXK A;  3NKN A;  2W5S A;  3NKM A;  4LRD A;  1KHN A;  2W8D A;  3M8W A;  3WAV A;  3IDD A;  1B8J A;  5L0B A;  1KH5 A;  1KHL A;  3UN2 A;  1ED9 A;  1Y7A A;  3LXQ A;  1KH9 A;  2W8S A;  1K7H A;  2VQR A;  2XRG A;  5C66 A;  1ELZ A;  1HDH A;  4N7T A;  1ZEB A;  5K4P A;  1AJD A;  4KAV A;  1ANI A;  1ELY A;  1ELX A;  1AJA A;  4CYS A;  3CMR A;  4NWX A;  4FDI A;  3DYC A;  4LRB A;  5LRM A;  4UOO A;  1FSU A;  3BDF A;  4UPH A;  1Y6V A;  5LQQ A;  5EGE A;  4CYR A;  4ZG6 A;  3ED4 A;  3E2D A;  5LIA A;  3DPC A;  4GTZ A;  5AJ9 A;  3T02 A;  4YR1 A;  1N2L A;  4ZG7 A;  1ZEF A;  1ALI A;  1ED8 A;  1EQJ A;  2GSN A;  2IFY A;  2RH6 A;  2W5W A;  1KHK A;  5GRR A;  3M8Z A;  3BDG A;  3NKO A;  3NVL A;  4LR7 A;  3BDG B;  4QAX A;  2W5X A;  4LRC A;  1E3C P;  2GA3 A;  3WBH A;  4TN0 A;  1URB A;  2IUC B;  4UPL A;  3SZZ A;  2XR9 A;  1EI6 A;  4LR2 A;  4B56 A;  3NKP A;  4NWJ A;  4CXU A;  3TWZ A;  5TJ3 A;  4GTY A;  4LQY A;  1EW8 A;  1HJK A;  4KM4 A;  3SZY A;  1EW9 A;  5EGH A;  4ZG9 A;  3M7V A;  5INH A;  5IJQ A;  3BDH A;  3NKQ A;  3T00 A;  5HRT A;  4FDJ A;  1AJC A;  1ZED A;  4LR9 A;  5GOV A;  3KD8 A;  5L0K A;  1E2S P;  4UOP A;  5LRN A;  1ALH A;  2X98 A;  2D1G A;  2GLQ A;  2W5T A;  1ALJ A;  4KJD A;  4CXS A;  1ANJ A;  1E33 P;  3UNY A;  4KAY A;  4LRE A;  5KXA A;  1KH4 A;  5DLT A;  4UPK A;  2W5R A;  1SHQ A;  1EJJ A;  2IUC A;  3IGZ B;  1AUK A;  2GSO A;  2GSU A;  3B5Q A;  3WAW A;  4KJG A;  1EW2 A;  5DLV A;  3MK2 A;  1E1Z P;  3IGY B;  3M8Y A;  3NKR A;  4MIV A;  4LRA A;  1AJB A;  4UPI A;  3UO0 A;  4MHX A;  3MK0 A;  3OT9 A;  3WAY A;  5IJS A;  1N2K A;  3MK1 A;  3TX0 A;  1P49 A;  2W5V A;  3UN5 A; 
#chains in the Genus database with same CATH homology
 2ANH A;  1URA A;  4MY4 A;  1HQA A;  1KHJ A;  2W5Q A;  1SHN A;  4UOR A;  5DLW A;  2QZU A;  2ZKT A;  4GTW A;  3WAX A;  4LRF A;  1ALK A;  1O99 A;  2G9Y A;  5L0E A;  3A52 A;  3T01 A;  3Q3Q A;  4ZGA A;  4GTX A;  1KH7 A;  4LR8 A;  3TG0 A;  3UN3 A;  1O98 A;  4CXK A;  3NKN A;  2W5S A;  3NKM A;  4LRD A;  1KHN A;  2W8D A;  3M8W A;  3WAV A;  3IDD A;  1B8J A;  5L0B A;  1KH5 A;  1KHL A;  3UN2 A;  1ED9 A;  1Y7A A;  3LXQ A;  1KH9 A;  2W8S A;  1K7H A;  2VQR A;  2XRG A;  5C66 A;  1ELZ A;  1HDH A;  4N7T A;  1ZEB A;  5K4P A;  1AJD A;  4KAV A;  1ANI A;  1ELY A;  1ELX A;  1AJA A;  4CYS A;  3CMR A;  4NWX A;  4FDI A;  3DYC A;  4LRB A;  5LRM A;  4UOO A;  1FSU A;  3BDF A;  4UPH A;  1Y6V A;  5LQQ A;  5EGE A;  4CYR A;  4ZG6 A;  3ED4 A;  3E2D A;  5LIA A;  3DPC A;  4GTZ A;  5AJ9 A;  3T02 A;  4YR1 A;  1N2L A;  4ZG7 A;  1ZEF A;  1ALI A;  1ED8 A;  1EQJ A;  2GSN A;  2IFY A;  2RH6 A;  2W5W A;  1KHK A;  5GRR A;  3M8Z A;  3BDG A;  3NKO A;  3NVL A;  4LR7 A;  3BDG B;  4QAX A;  2W5X A;  4LRC A;  1E3C P;  2GA3 A;  3WBH A;  4TN0 A;  1URB A;  2IUC B;  4UPL A;  3SZZ A;  2XR9 A;  1EI6 A;  4LR2 A;  4B56 A;  3NKP A;  4NWJ A;  4CXU A;  3TWZ A;  5TJ3 A;  4GTY A;  4LQY A;  1EW8 A;  1HJK A;  4KM4 A;  3SZY A;  1EW9 A;  5EGH A;  4ZG9 A;  3M7V A;  5INH A;  5IJQ A;  3BDH A;  3NKQ A;  3T00 A;  5HRT A;  4FDJ A;  1AJC A;  1ZED A;  4LR9 A;  5GOV A;  3KD8 A;  5L0K A;  1E2S P;  4UOP A;  5LRN A;  1ALH A;  2X98 A;  2D1G A;  2GLQ A;  2W5T A;  1ALJ A;  4KJD A;  4CXS A;  1ANJ A;  1E33 P;  3UNY A;  4KAY A;  4LRE A;  5KXA A;  1KH4 A;  5DLT A;  4UPK A;  2W5R A;  1SHQ A;  1EJJ A;  2IUC A;  3IGZ B;  1AUK A;  2GSO A;  2GSU A;  3B5Q A;  3WAW A;  4KJG A;  1EW2 A;  5DLV A;  3MK2 A;  1E1Z P;  3IGY B;  3M8Y A;  3NKR A;  4MIV A;  4LRA A;  1AJB A;  4UPI A;  3UO0 A;  4MHX A;  3MK0 A;  3OT9 A;  3WAY A;  5IJS A;  1N2K A;  3MK1 A;  3TX0 A;  1P49 A;  2W5V A;  3UN5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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