2J0TA

Crystal structure of the catalytic domain of mmp-1 in complex with the inhibitory domain of timp-1
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
161
structure length
161
Chain Sequence
GNPRWEQTHLTYRIENYTPDLPRADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGNLAHAFQPGPGIGGDAHFDEDERWTNNFREYNLHRVAAHELGHSLGLSHSTDIGALMYPSYTFSGDVQLAQDDIDGIQAIYGRSQN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the Catalytic Domain of Matrix Metalloproteinase-1 in Complex with the Inhibitory Domain of Tissue Inhibitor of Metalloproteinase-1.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords INTERSTITIAL COLLAGENASE
total genus 43
structure length 161
sequence length 161
chains with identical sequence B, C
ec nomenclature ec 3.4.24.7: Interstitial collagenase.
pdb deposition date 2006-08-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 2j0tA00
2E3XA 2HU6A 1I1IP 4XM7A 3L0VA 1J7NA 2X3CA 1JAPA 1KUGA 4WKEA 1FBLA 1CXVA 4R3VA 3WV1A 4ILWD 4EFSA 1ND1A 1OM6A 3DWBA 3O2XA 1KAPP 1BIWA 1EB6A 3G5CA 2FV5A 4H1QA 4H2EA 2K2GA 1KUHA 1QIBA 1G9KA 1UTZA 1IACA 3LUNA 1UMSA 1IADA 3LUMA 4G9LA 1XFVA 1XFXA 2MZEA 3F17A 2W0DA 3O64A 4A3WA 4GF1A 5CXAA 1PWPA 5D7WA 3VI1A 1HY7A 1CGEA 1C8TA 1KUFA 2TCLA 1CGFA 3LILA 1OM8A 4FXYP 2K9CA 5D1UA 4WF6A 5B5PA 3DPEA 2OY4A 4H82A 1WNIA 4L6TA 5B5OA 3RTTA 2OZRA 3HDAP 1BM6A 4PKUA 1G4KA 3F1AA 2I47A 2E2DA 3EHYA 5I43A 1DMTA 2KRJA 5BPAA 1Y8JA 1R54A 1ZVXA 5H8XA 2Y6DA 1ROSA 4IUWA 1XFYA 3E8RA 1MMQA 1BQOA 1ZXCA 3LQ0A 3KRYA 3SHIA 3OHLA 1AF0A 3U1RA 1FLSA 5I4OA 2J83A 3KEKA 1A85A 1D8FA 1C3IA 2J0TA 5D3CA 2L0RA 4PKRA 1QJIA 3Q2GA 4H30A 1SLMA 1D5JA 1K7GA 3LIRA 1UMTA 5LABA 1ZP5A 4GR0A 2DW0A 2PJTA 4GUYA 2CKIA 3WV3A 3HDBA 2JNPA 2OXWA 1RM8A 4QKZA 5BOTA 3K7NA 1I76A 1R55A 2SRTA 3F16A 1ASTA 1CQRA 4L19A 4GWMA 3LKAA 4H76A 2X3AA 4IJOA 3KWVC 1BZSA 3P24A 2EROA 4ZR5A 1GKCA 3LJZA 4G0DA 1BQQM 2OXZA 3TT4A 4HMAA 3LE9A 2WO8A 1G49A 3LIKA 3LGPA 1FM1A 1GXDA 1KUKA 1PWVA 2W12A 966CA 1Y0VA 2OXUA 1K7IA 1BKCE 1JAQA 1DTHA 3N2VA 1HOVA 4PKQA 3EDZA 2JSDA 3EDHA 3UVCA 4PKVA 2X3BA 3HY7A 1PWUA 3KMEA 2YIGA 3ZUKA 4DPEA 1UTTA 3EWJA 3EHXA 4FVLA 1PWQA 5JMYA 1CK7A 4DD8A 1BSWA 1K7QA 1Y93A 1IAEA 1IAAA 1ZXVA 2DW2A 3N2UA 1YP1A 3ZXHA 1KBCA 1R1JA 4FXQA 2FV9A 1O0TA 4H84A 3OHOA 2AIGP 3EDGA 1USNA 3AIGA 2CLTA 3HBUP 1O0QA 4JQGA 2YB9A 5I12A 3HBVP 3RTSA 3V96B 3KEJA 1XFUA 1QICA 4WZVA 3B92A 2XS4A 1OM7A 4AYKA 1RMZA 2N8RA 1HV5A 2A8HA 4I03A 830CA 1C7KA 1SATA 1EAKA 4GR3A 4DV8A 1G05A 2Z2DA 1CGLA 1R1HA 4AXQA 3LQBA 1OS9A 1YCMA 4GR8A 2MZHA 5I2ZA 3I7GA 2OI0A 1JJ9A 2OVZA 1OMJA 2QPJA 2POJA 1MNCA 3G42A 1Z3JA 2WO9A 1BKCA 2MLRA 4PKTA 2OY2A 1XUDA 4JA1A 3WV2A 2D1OA 4H3XA 1D8MA 1GE5A 5I3MA 2D1NA 2RJPA 5I0LA 2JT6A 1IAGA 1JKYA 5CZMA 2OW0A 3TS4A 1A86A 1GE7A 4GWNA 2OW1A 2W13A 5D2BA 3BA0A 1G12A 1D7XA 3USNA 5L79A 5BOYA 3I7IA 3GBOA 2DDYA 4A7BA 1SRPA 3DL1A 456CA 4CTHA 1B8YA 3HB2P 3DSLA 2ERPA 1AYKA 1GKDA 1PWWA 3KECA 1HTDA 5D1TA 1BUVM 4PKSA 1YQYA 1R1IA 1XFWA 2W14A 3B8ZA 4AUOA 1ZS0A 3KHIA 1MMPA 5CUHA 1OS2A 1CIZA 3AYUA 1QUAA 2O3EA 4Q1LA 1JK3A 2AYKA 1SLNA 1HFSA 3DPFA 3TSKA 1GO7P 3P1VA 1CAQA 1HFCA 2X7MA 3K7LA 2XS3A 3ZVSA 4PKWA 2JT5A 4WKIA 2O36A 2MLSA 3LK8A 2Y6CA 4H49A 2MZIA 4XCTA 3LJGA 1MMBA 1ZTQA 2USNA 3ELMA 1IABA 1KUIA 1UEAA 4J4MA 3VTGA 1S4BP 4XM8A 2ERQA 5L7FA 4WK7A 3EDIA 4ON1A 3TVCA 3F19A 2V4BA 1JANA 3LMCA 1YOUA 1MMRA 4DF9A 1L6JA 2DW1A 3NX7A 1GE6A 1JIWP 3HY9A 4JIJA 4I35A 2OW2A 1BUDA 3LJTA 2JIHA 4JP4A 1SMPA 3KMCA 3MA2A 2OW9A 4HX3A 1B3DA 1XURA 2W15A 1H71P 3AYKA 1BKCI 3DNGA 1OO9A 1XFZA 1JH1A 1GO8P 1QIAA 4IN9A 4XM6A 1EUBA 2WOAA 1JAOA 1AKLA 2RJQA 3F15A 3HYGA 3CKIA 4JPAA 4GQLA 4XBHA 1XUCA 4L63A 3F18A 1Q3AA 2DDFA 1SU3A 3L0TA 1QJJA 5D1SA 1I73A 3LEAA 4FU4A 1ATLA 3Q2HA 2OVXA 3B2ZA 4AIGA 1JIZA
chains in the Genus database with same CATH superfamily
2E3XA 2HU6A 1I1IP 4XM7A 3L0VA 1J7NA 2X3CA 1JAPA 1KUGA 4WKEA 1FBLA 1CXVA 4R3VA 3WV1A 4ILWD 4EFSA 1ND1A 1OM6A 3DWBA 3O2XA 1KAPP 1BIWA 1EB6A 3G5CA 2FV5A 4H1QA 1TVIA 4H2EA 2K2GA 1KUHA 1QIBA 1G9KA 1UTZA 1IACA 3LUNA 1UMSA 1IADA 3LUMA 4G9LA 1XFVA 1XFXA 2MZEA 3F17A 2W0DA 3O64A 4A3WA 4GF1A 5CXAA 1PWPA 5D7WA 3VI1A 1HY7A 1CGEA 1C8TA 1KUFA 2TCLA 1CGFA 3LILA 1OM8A 4FXYP 2K9CA 2YUFA 5D1UA 4WF6A 5B5PA 3DPEA 2OY4A 4H82A 1WNIA 4L6TA 5B5OA 3RTTA 2OZRA 3HDAP 1BM6A 4PKUA 1G4KA 3F1AA 2I47A 2E2DA 3EHYA 5I43A 1DMTA 2KRJA 5BPAA 1Y8JA 1R54A 4L7AA 1ZVXA 5H8XA 2Y6DA 1ROSA 4IUWA 1XFYA 3E8RA 1MMQA 1BQOA 1ZXCA 3LQ0A 3KRYA 3SHIA 3OHLA 1AF0A 3U1RA 1FLSA 5I4OA 2J83A 3KEKA 1A85A 1D8FA 1C3IA 2J0TA 5D3CA 2L0RA 4PKRA 1QJIA 3Q2GA 4H30A 1SLMA 1D5JA 1K7GA 3LIRA 1UMTA 5LABA 1XM5A 1ZP5A 4GR0A 2DW0A 2PJTA 4GUYA 2CKIA 3WV3A 1OZ9A 3HDBA 2JNPA 2OXWA 1RM8A 4QKZA 5BOTA 3K7NA 1I76A 1R55A 2SRTA 3F16A 1ASTA 1CQRA 4L19A 1XAXA 4GWMA 3LKAA 4H76A 2X3AA 4IJOA 3KWVC 1BZSA 3P24A 2EROA 4ZR5A 1GKCA 3LJZA 4G0DA 1BQQM 2OXZA 3TT4A 4HMAA 3LE9A 2WO8A 1G49A 3LIKA 3LGPA 1FM1A 1GXDA 1KUKA 1PWVA 2W12A 966CA 1Y0VA 2OXUA 1K7IA 1BKCE 1JAQA 1DTHA 3N2VA 1HOVA 4PKQA 3EDZA 2JSDA 3EDHA 3UVCA 4PKVA 2X3BA 3HY7A 1PWUA 3KMEA 2YIGA 3ZUKA 4DPEA 1UTTA 3EWJA 3EHXA 4FVLA 1PWQA 5JMYA 1CK7A 4DD8A 1BSWA 1K7QA 1Y93A 1IAEA 1IAAA 1ZXVA 2DW2A 3DTKA 3N2UA 1YP1A 3ZXHA 1KBCA 1R1JA 4FXQA 2FV9A 1O0TA 4H84A 3OHOA 2AIGP 3EDGA 3DTEA 1USNA 3AIGA 2CLTA 3HBUP 1O0QA 4JQGA 2YB9A 5I12A 3HBVP 3RTSA 3V96B 3KEJA 1XFUA 1QICA 4WZVA 3B92A 2XS4A 1OM7A 4AYKA 1RMZA 2N8RA 1HV5A 2A8HA 4I03A 830CA 1C7KA 1SATA 1EAKA 4GR3A 4DV8A 1G05A 2Z2DA 1CGLA 1R1HA 4AXQA 3LQBA 1OS9A 1YCMA 4GR8A 2MZHA 5I2ZA 3I7GA 2OI0A 1JJ9A 2OVZA 1OMJA 2QPJA 2POJA 1MNCA 3G42A 1Z3JA 2WO9A 1BKCA 2MLRA 4PKTA 2OY2A 1XUDA 4JA1A 3WV2A 2D1OA 4H3XA 1D8MA 1GE5A 5I3MA 2D1NA 2RJPA 5I0LA 2JT6A 1IAGA 1JKYA 5CZMA 2OW0A 3TS4A 1A86A 1GE7A 4GWNA 2OW1A 2W13A 5D2BA 3BA0A 1G12A 1D7XA 3USNA 5L79A 5BOYA 3I7IA 3GBOA 2DDYA 4A7BA 1SRPA 3DL1A 456CA 4CTHA 1B8YA 3HB2P 3DSLA 2ERPA 1AYKA 1GKDA 1PWWA 3KECA 1HTDA 5D1TA 1BUVM 4PKSA 1YQYA 1R1IA 1XFWA 2W14A 3B8ZA 4AUOA 1ZS0A 3KHIA 1MMPA 5CUHA 1OS2A 1CIZA 3AYUA 1QUAA 2O3EA 4Q1LA 1JK3A 2AYKA 1SLNA 1HFSA 3DPFA 3TSKA 1GO7P 3P1VA 1CAQA 1HFCA 2X7MA 3K7LA 2XS3A 3ZVSA 4PKWA 2JT5A 4WKIA 2O36A 2MLSA 3LK8A 2Y6CA 3DTIA 4H49A 2MZIA 4XCTA 3LJGA 1MMBA 1ZTQA 2USNA 3ELMA 1IABA 1KUIA 1UEAA 4J4MA 3VTGA 1S4BP 4XM8A 2ERQA 5L7FA 4WK7A 3EDIA 4ON1A 3TVCA 3F19A 2V4BA 1JANA 3LMCA 1YOUA 1MMRA 4DF9A 1L6JA 2DW1A 3NX7A 1GE6A 1JIWP 3HY9A 4JIJA 4I35A 2OW2A 1BUDA 3LJTA 2JIHA 4JP4A 1SMPA 3KMCA 3MA2A 2OW9A 4HX3A 1B3DA 1XURA 2W15A 1H71P 3AYKA 1BKCI 3DNGA 1OO9A 1XFZA 1JH1A 1GO8P 1QIAA 4IN9A 4XM6A 1EUBA 2WOAA 1JAOA 1AKLA 2RJQA 3F15A 3HYGA 3CKIA 4JPAA 4GQLA 4XBHA 1XUCA 4L63A 3F18A 1Q3AA 2DDFA 1SU3A 3L0TA 1QJJA 5D1SA 1I73A 3LEAA 4FU4A 1ATLA 3Q2HA 2OVXA 3B2ZA 4AIGA 1JIZA
chains in the Genus database with same CATH topology
2E3XA 2HU6A 1I1IP 4XM7A 3L0VA 1J7NA 2X3CA 1JAPA 1KUGA 4WKEA 1FBLA 1CXVA 4R3VA 3WV1A 4ILWD 4EFSA 1ND1A 1OM6A 3DWBA 3O2XA 1KAPP 1BIWA 1EB6A 3G5CA 2FV5A 4H1QA 4H2EA 2K2GA 1KUHA 1QIBA 1G9KA 1UTZA 1IACA 3LUNA 1UMSA 1IADA 3LUMA 4G9LA 1XFVA 1XFXA 2MZEA 3F17A 2W0DA 3O64A 4A3WA 4GF1A 5CXAA 1PWPA 5D7WA 3VI1A 1HY7A 1CGEA 1C8TA 1KUFA 2TCLA 1CGFA 3LILA 1OM8A 4FXYP 2K9CA 2YUFA 5D1UA 4WF6A 5B5PA 3DPEA 2OY4A 4H82A 1WNIA 4L6TA 5B5OA 3RTTA 2OZRA 3HDAP 1BM6A 4PKUA 1G4KA 3F1AA 2I47A 2E2DA 3EHYA 5I43A 1DMTA 2KRJA 5BPAA 1Y8JA 1R54A 4L7AA 1ZVXA 5H8XA 2Y6DA 1ROSA 4IUWA 1XFYA 3E8RA 1MMQA 1BQOA 1ZXCA 3LQ0A 3KRYA 3SHIA 3OHLA 1AF0A 3U1RA 1FLSA 5I4OA 2J83A 3KEKA 1A85A 1D8FA 1C3IA 2J0TA 5D3CA 2L0RA 4PKRA 1QJIA 3Q2GA 4H30A 1SLMA 1D5JA 1K7GA 3LIRA 1UMTA 5LABA 1ZP5A 4GR0A 2DW0A 2PJTA 4GUYA 2CKIA 3WV3A 3HDBA 2JNPA 2OXWA 1RM8A 4QKZA 5BOTA 3K7NA 1I76A 1R55A 2SRTA 3F16A 1ASTA 1CQRA 4L19A 4GWMA 3LKAA 4H76A 2X3AA 4IJOA 3KWVC 1BZSA 3P24A 2EROA 4ZR5A 1GKCA 3LJZA 4G0DA 1BQQM 2OXZA 3TT4A 4HMAA 3LE9A 2WO8A 1G49A 3LIKA 3LGPA 1FM1A 1GXDA 1KUKA 1PWVA 2W12A 966CA 1Y0VA 2OXUA 1K7IA 1BKCE 1JAQA 1DTHA 3N2VA 1HOVA 4PKQA 3EDZA 2JSDA 3EDHA 3UVCA 4PKVA 2X3BA 3HY7A 1PWUA 3KMEA 2YIGA 3ZUKA 4DPEA 1UTTA 3EWJA 3EHXA 4FVLA 1PWQA 5JMYA 1CK7A 4DD8A 1BSWA 1K7QA 1Y93A 1IAEA 1IAAA 1ZXVA 2DW2A 3DTKA 3N2UA 1YP1A 3ZXHA 1KBCA 1R1JA 4FXQA 2FV9A 1O0TA 4H84A 3OHOA 2AIGP 3EDGA 3DTEA 1USNA 3AIGA 2CLTA 3HBUP 1O0QA 4JQGA 2YB9A 5I12A 3HBVP 3RTSA 3V96B 3KEJA 1XFUA 1QICA 4WZVA 3B92A 2XS4A 1OM7A 4AYKA 1RMZA 2N8RA 1HV5A 2A8HA 4I03A 830CA 1C7KA 1SATA 1EAKA 4GR3A 4DV8A 1G05A 2Z2DA 1CGLA 1R1HA 4AXQA 3LQBA 1OS9A 1YCMA 4GR8A 2MZHA 5I2ZA 3I7GA 2OI0A 1JJ9A 2OVZA 1OMJA 2QPJA 2POJA 1MNCA 3G42A 1Z3JA 2WO9A 1BKCA 2MLRA 4PKTA 2OY2A 1XUDA 4JA1A 3WV2A 2D1OA 4H3XA 1D8MA 1GE5A 5I3MA 2D1NA 2RJPA 5I0LA 2JT6A 1IAGA 1JKYA 5CZMA 2OW0A 3TS4A 1A86A 1GE7A 4GWNA 2OW1A 2W13A 5D2BA 3BA0A 1G12A 1D7XA 3USNA 5L79A 5BOYA 3I7IA 3GBOA 2DDYA 4A7BA 1SRPA 3DL1A 456CA 4CTHA 1B8YA 3HB2P 3DSLA 2ERPA 1AYKA 1GKDA 1PWWA 3KECA 1HTDA 5D1TA 1BUVM 4PKSA 1YQYA 1R1IA 1XFWA 2W14A 3B8ZA 4AUOA 1ZS0A 3KHIA 1MMPA 5CUHA 1OS2A 1CIZA 3AYUA 1QUAA 2O3EA 4Q1LA 1JK3A 2AYKA 1SLNA 1HFSA 3DPFA 3TSKA 1GO7P 3P1VA 1CAQA 1HFCA 2X7MA 3K7LA 2XS3A 3ZVSA 4PKWA 2JT5A 4WKIA 2O36A 2MLSA 3LK8A 2Y6CA 3DTIA 4H49A 2MZIA 4XCTA 3LJGA 1MMBA 1ZTQA 2USNA 3ELMA 1IABA 1KUIA 1UEAA 4J4MA 3VTGA 1S4BP 4XM8A 2ERQA 5L7FA 4WK7A 3EDIA 4ON1A 3TVCA 3F19A 2V4BA 1JANA 3LMCA 1YOUA 1MMRA 4DF9A 1L6JA 2DW1A 3NX7A 1GE6A 1JIWP 3HY9A 4JIJA 4I35A 2OW2A 1BUDA 3LJTA 2JIHA 4JP4A 1SMPA 3KMCA 3MA2A 2OW9A 4HX3A 1B3DA 1XURA 2W15A 1H71P 3AYKA 1BKCI 3DNGA 1OO9A 1XFZA 1JH1A 1GO8P 1QIAA 4IN9A 4XM6A 1EUBA 2WOAA 1JAOA 1AKLA 2RJQA 3F15A 3HYGA 3CKIA 4JPAA 4GQLA 4XBHA 1XUCA 4L63A 3F18A 1Q3AA 2DDFA 1SU3A 3L0TA 1QJJA 5D1SA 1I73A 3LEAA 4FU4A 1ATLA 3Q2HA 2OVXA 3B2ZA 4AIGA 1JIZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2E3X A;  2HU6 A;  1I1I P;  4XM7 A;  3L0V A;  1J7N A;  2X3C A;  1JAP A;  1KUG A;  4WKE A;  1FBL A;  1CXV A;  4R3V A;  3WV1 A;  4ILW D;  4EFS A;  1ND1 A;  1OM6 A;  3DWB A;  3O2X A;  1KAP P;  1BIW A;  1EB6 A;  3G5C A;  2FV5 A;  4H1Q A;  4H2E A;  2K2G A;  1KUH A;  1QIB A;  1G9K A;  1UTZ A;  1IAC A;  3LUN A;  1UMS A;  1IAD A;  3LUM A;  4G9L A;  1XFV A;  1XFX A;  2MZE A;  3F17 A;  2W0D A;  3O64 A;  4A3W A;  4GF1 A;  5CXA A;  1PWP A;  5D7W A;  3VI1 A;  1HY7 A;  1CGE A;  1C8T A;  1KUF A;  2TCL A;  1CGF A;  3LIL A;  1OM8 A;  4FXY P;  2K9C A;  5D1U A;  4WF6 A;  5B5P A;  3DPE A;  2OY4 A;  4H82 A;  1WNI A;  4L6T A;  5B5O A;  3RTT A;  2OZR A;  3HDA P;  1BM6 A;  4PKU A;  1G4K A;  3F1A A;  2I47 A;  2E2D A;  3EHY A;  5I43 A;  1DMT A;  2KRJ A;  5BPA A;  1Y8J A;  1R54 A;  1ZVX A;  5H8X A;  2Y6D A;  1ROS A;  4IUW A;  1XFY A;  3E8R A;  1MMQ A;  1BQO A;  1ZXC A;  3LQ0 A;  3KRY A;  3SHI A;  3OHL A;  1AF0 A;  3U1R A;  1FLS A;  5I4O A;  2J83 A;  3KEK A;  1A85 A;  1D8F A;  1C3I A;  2J0T A;  5D3C A;  2L0R A;  4PKR A;  1QJI A;  3Q2G A;  4H30 A;  1SLM A;  1D5J A;  1K7G A;  3LIR A;  1UMT A;  5LAB A;  1ZP5 A;  4GR0 A;  2DW0 A;  2PJT A;  4GUY A;  2CKI A;  3WV3 A;  3HDB A;  2JNP A;  2OXW A;  1RM8 A;  4QKZ A;  5BOT A;  3K7N A;  1I76 A;  1R55 A;  2SRT A;  3F16 A;  1AST A;  1CQR A;  4L19 A;  4GWM A;  3LKA A;  4H76 A;  2X3A A;  4IJO A;  3KWV C;  1BZS A;  3P24 A;  2ERO A;  4ZR5 A;  1GKC A;  3LJZ A;  4G0D A;  1BQQ M;  2OXZ A;  3TT4 A;  4HMA A;  3LE9 A;  2WO8 A;  1G49 A;  3LIK A;  3LGP A;  1FM1 A;  1GXD A;  1KUK A;  1PWV A;  2W12 A;  966C A;  1Y0V A;  2OXU A;  1K7I A;  1BKC E;  1JAQ A;  1DTH A;  3N2V A;  1HOV A;  4PKQ A;  3EDZ A;  2JSD A;  3EDH A;  3UVC A;  4PKV A;  2X3B A;  3HY7 A;  1PWU A;  3KME A;  2YIG A;  3ZUK A;  4DPE A;  1UTT A;  3EWJ A;  3EHX A;  4FVL A;  1PWQ A;  5JMY A;  1CK7 A;  4DD8 A;  1BSW A;  1K7Q A;  1Y93 A;  1IAE A;  1IAA A;  1ZXV A;  2DW2 A;  3N2U A;  1YP1 A;  3ZXH A;  1KBC A;  1R1J A;  4FXQ A;  2FV9 A;  1O0T A;  4H84 A;  3OHO A;  2AIG P;  3EDG A;  1USN A;  3AIG A;  2CLT A;  3HBU P;  1O0Q A;  4JQG A;  2YB9 A;  5I12 A;  3HBV P;  3RTS A;  3V96 B;  3KEJ A;  1XFU A;  1QIC A;  4WZV A;  3B92 A;  2XS4 A;  1OM7 A;  4AYK A;  1RMZ A;  2N8R A;  1HV5 A;  2A8H A;  4I03 A;  830C A;  1C7K A;  1SAT A;  1EAK A;  4GR3 A;  4DV8 A;  1G05 A;  2Z2D A;  1CGL A;  1R1H A;  4AXQ A;  3LQB A;  1OS9 A;  1YCM A;  4GR8 A;  2MZH A;  5I2Z A;  3I7G A;  2OI0 A;  1JJ9 A;  2OVZ A;  1OMJ A;  2QPJ A;  2POJ A;  1MNC A;  3G42 A;  1Z3J A;  2WO9 A;  1BKC A;  2MLR A;  4PKT A;  2OY2 A;  1XUD A;  4JA1 A;  3WV2 A;  2D1O A;  4H3X A;  1D8M A;  1GE5 A;  5I3M A;  2D1N A;  2RJP A;  5I0L A;  2JT6 A;  1IAG A;  1JKY A;  5CZM A;  2OW0 A;  3TS4 A;  1A86 A;  1GE7 A;  4GWN A;  2OW1 A;  2W13 A;  5D2B A;  3BA0 A;  1G12 A;  1D7X A;  3USN A;  5L79 A;  5BOY A;  3I7I A;  3GBO A;  2DDY A;  4A7B A;  1SRP A;  3DL1 A;  456C A;  4CTH A;  1B8Y A;  3HB2 P;  3DSL A;  2ERP A;  1AYK A;  1GKD A;  1PWW A;  3KEC A;  1HTD A;  5D1T A;  1BUV M;  4PKS A;  1YQY A;  1R1I A;  1XFW A;  2W14 A;  3B8Z A;  4AUO A;  1ZS0 A;  3KHI A;  1MMP A;  5CUH A;  1OS2 A;  1CIZ A;  3AYU A;  1QUA A;  2O3E A;  4Q1L A;  1JK3 A;  2AYK A;  1SLN A;  1HFS A;  3DPF A;  3TSK A;  1GO7 P;  3P1V A;  1CAQ A;  1HFC A;  2X7M A;  3K7L A;  2XS3 A;  3ZVS A;  4PKW A;  2JT5 A;  4WKI A;  2O36 A;  2MLS A;  3LK8 A;  2Y6C A;  4H49 A;  2MZI A;  4XCT A;  3LJG A;  1MMB A;  1ZTQ A;  2USN A;  3ELM A;  1IAB A;  1KUI A;  1UEA A;  4J4M A;  3VTG A;  1S4B P;  4XM8 A;  2ERQ A;  5L7F A;  4WK7 A;  3EDI A;  4ON1 A;  3TVC A;  3F19 A;  2V4B A;  1JAN A;  3LMC A;  1YOU A;  1MMR A;  4DF9 A;  1L6J A;  2DW1 A;  3NX7 A;  1GE6 A;  1JIW P;  3HY9 A;  4JIJ A;  4I35 A;  2OW2 A;  1BUD A;  3LJT A;  2JIH A;  4JP4 A;  1SMP A;  3KMC A;  3MA2 A;  2OW9 A;  4HX3 A;  1B3D A;  1XUR A;  2W15 A;  1H71 P;  3AYK A;  1BKC I;  3DNG A;  1OO9 A;  1XFZ A;  1JH1 A;  1GO8 P;  1QIA A;  4IN9 A;  4XM6 A;  1EUB A;  2WOA A;  1JAO A;  1AKL A;  2RJQ A;  3F15 A;  3HYG A;  3CKI A;  4JPA A;  4GQL A;  4XBH A;  1XUC A;  4L63 A;  3F18 A;  1Q3A A;  2DDF A;  1SU3 A;  3L0T A;  1QJJ A;  5D1S A;  1I73 A;  3LEA A;  4FU4 A;  1ATL A;  3Q2H A;  2OVX A;  3B2Z A;  4AIG A;  1JIZ A; 
#chains in the Genus database with same CATH topology
 2E3X A;  2HU6 A;  1I1I P;  4XM7 A;  3L0V A;  1J7N A;  2X3C A;  1JAP A;  1KUG A;  4WKE A;  1FBL A;  1CXV A;  4R3V A;  3WV1 A;  4ILW D;  4EFS A;  1ND1 A;  1OM6 A;  3DWB A;  3O2X A;  1KAP P;  1BIW A;  1EB6 A;  3G5C A;  2FV5 A;  4H1Q A;  1TVI A;  4H2E A;  2K2G A;  1KUH A;  1QIB A;  1G9K A;  1UTZ A;  1IAC A;  3LUN A;  1UMS A;  1IAD A;  3LUM A;  4G9L A;  1XFV A;  1XFX A;  2MZE A;  3F17 A;  2W0D A;  3O64 A;  4A3W A;  4GF1 A;  5CXA A;  1PWP A;  5D7W A;  3VI1 A;  1HY7 A;  1CGE A;  1C8T A;  1KUF A;  2TCL A;  1CGF A;  3LIL A;  1OM8 A;  4FXY P;  2K9C A;  2YUF A;  5D1U A;  4WF6 A;  5B5P A;  3DPE A;  2OY4 A;  4H82 A;  1WNI A;  4L6T A;  5B5O A;  3RTT A;  2OZR A;  3HDA P;  1BM6 A;  4PKU A;  1G4K A;  3F1A A;  2I47 A;  2E2D A;  3EHY A;  5I43 A;  1DMT A;  2KRJ A;  5BPA A;  1Y8J A;  1R54 A;  4L7A A;  1ZVX A;  5H8X A;  2Y6D A;  1ROS A;  4IUW A;  1XFY A;  3E8R A;  1MMQ A;  1BQO A;  1ZXC A;  3LQ0 A;  3KRY A;  3SHI A;  3OHL A;  1AF0 A;  3U1R A;  1FLS A;  5I4O A;  2J83 A;  3KEK A;  1A85 A;  1D8F A;  1C3I A;  2J0T A;  5D3C A;  2L0R A;  4PKR A;  1QJI A;  3Q2G A;  4H30 A;  1SLM A;  1D5J A;  1K7G A;  3LIR A;  1UMT A;  5LAB A;  1XM5 A;  1ZP5 A;  4GR0 A;  2DW0 A;  2PJT A;  4GUY A;  2CKI A;  3WV3 A;  1OZ9 A;  3HDB A;  2JNP A;  2OXW A;  1RM8 A;  4QKZ A;  5BOT A;  3K7N A;  1I76 A;  1R55 A;  2SRT A;  3F16 A;  1AST A;  1CQR A;  4L19 A;  1XAX A;  4GWM A;  3LKA A;  4H76 A;  2X3A A;  4IJO A;  3KWV C;  1BZS A;  3P24 A;  2ERO A;  4ZR5 A;  1GKC A;  3LJZ A;  4G0D A;  1BQQ M;  2OXZ A;  3TT4 A;  4HMA A;  3LE9 A;  2WO8 A;  1G49 A;  3LIK A;  3LGP A;  1FM1 A;  1GXD A;  1KUK A;  1PWV A;  2W12 A;  966C A;  1Y0V A;  2OXU A;  1K7I A;  1BKC E;  1JAQ A;  1DTH A;  3N2V A;  1HOV A;  4PKQ A;  3EDZ A;  2JSD A;  3EDH A;  3UVC A;  4PKV A;  2X3B A;  3HY7 A;  1PWU A;  3KME A;  2YIG A;  3ZUK A;  4DPE A;  1UTT A;  3EWJ A;  3EHX A;  4FVL A;  1PWQ A;  5JMY A;  1CK7 A;  4DD8 A;  1BSW A;  1K7Q A;  1Y93 A;  1IAE A;  1IAA A;  1ZXV A;  2DW2 A;  3DTK A;  3N2U A;  1YP1 A;  3ZXH A;  1KBC A;  1R1J A;  4FXQ A;  2FV9 A;  1O0T A;  4H84 A;  3OHO A;  2AIG P;  3EDG A;  3DTE A;  1USN A;  3AIG A;  2CLT A;  3HBU P;  1O0Q A;  4JQG A;  2YB9 A;  5I12 A;  3HBV P;  3RTS A;  3V96 B;  3KEJ A;  1XFU A;  1QIC A;  4WZV A;  3B92 A;  2XS4 A;  1OM7 A;  4AYK A;  1RMZ A;  2N8R A;  1HV5 A;  2A8H A;  4I03 A;  830C A;  1C7K A;  1SAT A;  1EAK A;  4GR3 A;  4DV8 A;  1G05 A;  2Z2D A;  1CGL A;  1R1H A;  4AXQ A;  3LQB A;  1OS9 A;  1YCM A;  4GR8 A;  2MZH A;  5I2Z A;  3I7G A;  2OI0 A;  1JJ9 A;  2OVZ A;  1OMJ A;  2QPJ A;  2POJ A;  1MNC A;  3G42 A;  1Z3J A;  2WO9 A;  1BKC A;  2MLR A;  4PKT A;  2OY2 A;  1XUD A;  4JA1 A;  3WV2 A;  2D1O A;  4H3X A;  1D8M A;  1GE5 A;  5I3M A;  2D1N A;  2RJP A;  5I0L A;  2JT6 A;  1IAG A;  1JKY A;  5CZM A;  2OW0 A;  3TS4 A;  1A86 A;  1GE7 A;  4GWN A;  2OW1 A;  2W13 A;  5D2B A;  3BA0 A;  1G12 A;  1D7X A;  3USN A;  5L79 A;  5BOY A;  3I7I A;  3GBO A;  2DDY A;  4A7B A;  1SRP A;  3DL1 A;  456C A;  4CTH A;  1B8Y A;  3HB2 P;  3DSL A;  2ERP A;  1AYK A;  1GKD A;  1PWW A;  3KEC A;  1HTD A;  5D1T A;  1BUV M;  4PKS A;  1YQY A;  1R1I A;  1XFW A;  2W14 A;  3B8Z A;  4AUO A;  1ZS0 A;  3KHI A;  1MMP A;  5CUH A;  1OS2 A;  1CIZ A;  3AYU A;  1QUA A;  2O3E A;  4Q1L A;  1JK3 A;  2AYK A;  1SLN A;  1HFS A;  3DPF A;  3TSK A;  1GO7 P;  3P1V A;  1CAQ A;  1HFC A;  2X7M A;  3K7L A;  2XS3 A;  3ZVS A;  4PKW A;  2JT5 A;  4WKI A;  2O36 A;  2MLS A;  3LK8 A;  2Y6C A;  3DTI A;  4H49 A;  2MZI A;  4XCT A;  3LJG A;  1MMB A;  1ZTQ A;  2USN A;  3ELM A;  1IAB A;  1KUI A;  1UEA A;  4J4M A;  3VTG A;  1S4B P;  4XM8 A;  2ERQ A;  5L7F A;  4WK7 A;  3EDI A;  4ON1 A;  3TVC A;  3F19 A;  2V4B A;  1JAN A;  3LMC A;  1YOU A;  1MMR A;  4DF9 A;  1L6J A;  2DW1 A;  3NX7 A;  1GE6 A;  1JIW P;  3HY9 A;  4JIJ A;  4I35 A;  2OW2 A;  1BUD A;  3LJT A;  2JIH A;  4JP4 A;  1SMP A;  3KMC A;  3MA2 A;  2OW9 A;  4HX3 A;  1B3D A;  1XUR A;  2W15 A;  1H71 P;  3AYK A;  1BKC I;  3DNG A;  1OO9 A;  1XFZ A;  1JH1 A;  1GO8 P;  1QIA A;  4IN9 A;  4XM6 A;  1EUB A;  2WOA A;  1JAO A;  1AKL A;  2RJQ A;  3F15 A;  3HYG A;  3CKI A;  4JPA A;  4GQL A;  4XBH A;  1XUC A;  4L63 A;  3F18 A;  1Q3A A;  2DDF A;  1SU3 A;  3L0T A;  1QJJ A;  5D1S A;  1I73 A;  3LEA A;  4FU4 A;  1ATL A;  3Q2H A;  2OVX A;  3B2Z A;  4AIG A;  1JIZ A; 
#chains in the Genus database with same CATH homology
 2E3X A;  2HU6 A;  1I1I P;  4XM7 A;  3L0V A;  1J7N A;  2X3C A;  1JAP A;  1KUG A;  4WKE A;  1FBL A;  1CXV A;  4R3V A;  3WV1 A;  4ILW D;  4EFS A;  1ND1 A;  1OM6 A;  3DWB A;  3O2X A;  1KAP P;  1BIW A;  1EB6 A;  3G5C A;  2FV5 A;  4H1Q A;  4H2E A;  2K2G A;  1KUH A;  1QIB A;  1G9K A;  1UTZ A;  1IAC A;  3LUN A;  1UMS A;  1IAD A;  3LUM A;  4G9L A;  1XFV A;  1XFX A;  2MZE A;  3F17 A;  2W0D A;  3O64 A;  4A3W A;  4GF1 A;  5CXA A;  1PWP A;  5D7W A;  3VI1 A;  1HY7 A;  1CGE A;  1C8T A;  1KUF A;  2TCL A;  1CGF A;  3LIL A;  1OM8 A;  4FXY P;  2K9C A;  2YUF A;  5D1U A;  4WF6 A;  5B5P A;  3DPE A;  2OY4 A;  4H82 A;  1WNI A;  4L6T A;  5B5O A;  3RTT A;  2OZR A;  3HDA P;  1BM6 A;  4PKU A;  1G4K A;  3F1A A;  2I47 A;  2E2D A;  3EHY A;  5I43 A;  1DMT A;  2KRJ A;  5BPA A;  1Y8J A;  1R54 A;  4L7A A;  1ZVX A;  5H8X A;  2Y6D A;  1ROS A;  4IUW A;  1XFY A;  3E8R A;  1MMQ A;  1BQO A;  1ZXC A;  3LQ0 A;  3KRY A;  3SHI A;  3OHL A;  1AF0 A;  3U1R A;  1FLS A;  5I4O A;  2J83 A;  3KEK A;  1A85 A;  1D8F A;  1C3I A;  2J0T A;  5D3C A;  2L0R A;  4PKR A;  1QJI A;  3Q2G A;  4H30 A;  1SLM A;  1D5J A;  1K7G A;  3LIR A;  1UMT A;  5LAB A;  1ZP5 A;  4GR0 A;  2DW0 A;  2PJT A;  4GUY A;  2CKI A;  3WV3 A;  3HDB A;  2JNP A;  2OXW A;  1RM8 A;  4QKZ A;  5BOT A;  3K7N A;  1I76 A;  1R55 A;  2SRT A;  3F16 A;  1AST A;  1CQR A;  4L19 A;  4GWM A;  3LKA A;  4H76 A;  2X3A A;  4IJO A;  3KWV C;  1BZS A;  3P24 A;  2ERO A;  4ZR5 A;  1GKC A;  3LJZ A;  4G0D A;  1BQQ M;  2OXZ A;  3TT4 A;  4HMA A;  3LE9 A;  2WO8 A;  1G49 A;  3LIK A;  3LGP A;  1FM1 A;  1GXD A;  1KUK A;  1PWV A;  2W12 A;  966C A;  1Y0V A;  2OXU A;  1K7I A;  1BKC E;  1JAQ A;  1DTH A;  3N2V A;  1HOV A;  4PKQ A;  3EDZ A;  2JSD A;  3EDH A;  3UVC A;  4PKV A;  2X3B A;  3HY7 A;  1PWU A;  3KME A;  2YIG A;  3ZUK A;  4DPE A;  1UTT A;  3EWJ A;  3EHX A;  4FVL A;  1PWQ A;  5JMY A;  1CK7 A;  4DD8 A;  1BSW A;  1K7Q A;  1Y93 A;  1IAE A;  1IAA A;  1ZXV A;  2DW2 A;  3DTK A;  3N2U A;  1YP1 A;  3ZXH A;  1KBC A;  1R1J A;  4FXQ A;  2FV9 A;  1O0T A;  4H84 A;  3OHO A;  2AIG P;  3EDG A;  3DTE A;  1USN A;  3AIG A;  2CLT A;  3HBU P;  1O0Q A;  4JQG A;  2YB9 A;  5I12 A;  3HBV P;  3RTS A;  3V96 B;  3KEJ A;  1XFU A;  1QIC A;  4WZV A;  3B92 A;  2XS4 A;  1OM7 A;  4AYK A;  1RMZ A;  2N8R A;  1HV5 A;  2A8H A;  4I03 A;  830C A;  1C7K A;  1SAT A;  1EAK A;  4GR3 A;  4DV8 A;  1G05 A;  2Z2D A;  1CGL A;  1R1H A;  4AXQ A;  3LQB A;  1OS9 A;  1YCM A;  4GR8 A;  2MZH A;  5I2Z A;  3I7G A;  2OI0 A;  1JJ9 A;  2OVZ A;  1OMJ A;  2QPJ A;  2POJ A;  1MNC A;  3G42 A;  1Z3J A;  2WO9 A;  1BKC A;  2MLR A;  4PKT A;  2OY2 A;  1XUD A;  4JA1 A;  3WV2 A;  2D1O A;  4H3X A;  1D8M A;  1GE5 A;  5I3M A;  2D1N A;  2RJP A;  5I0L A;  2JT6 A;  1IAG A;  1JKY A;  5CZM A;  2OW0 A;  3TS4 A;  1A86 A;  1GE7 A;  4GWN A;  2OW1 A;  2W13 A;  5D2B A;  3BA0 A;  1G12 A;  1D7X A;  3USN A;  5L79 A;  5BOY A;  3I7I A;  3GBO A;  2DDY A;  4A7B A;  1SRP A;  3DL1 A;  456C A;  4CTH A;  1B8Y A;  3HB2 P;  3DSL A;  2ERP A;  1AYK A;  1GKD A;  1PWW A;  3KEC A;  1HTD A;  5D1T A;  1BUV M;  4PKS A;  1YQY A;  1R1I A;  1XFW A;  2W14 A;  3B8Z A;  4AUO A;  1ZS0 A;  3KHI A;  1MMP A;  5CUH A;  1OS2 A;  1CIZ A;  3AYU A;  1QUA A;  2O3E A;  4Q1L A;  1JK3 A;  2AYK A;  1SLN A;  1HFS A;  3DPF A;  3TSK A;  1GO7 P;  3P1V A;  1CAQ A;  1HFC A;  2X7M A;  3K7L A;  2XS3 A;  3ZVS A;  4PKW A;  2JT5 A;  4WKI A;  2O36 A;  2MLS A;  3LK8 A;  2Y6C A;  3DTI A;  4H49 A;  2MZI A;  4XCT A;  3LJG A;  1MMB A;  1ZTQ A;  2USN A;  3ELM A;  1IAB A;  1KUI A;  1UEA A;  4J4M A;  3VTG A;  1S4B P;  4XM8 A;  2ERQ A;  5L7F A;  4WK7 A;  3EDI A;  4ON1 A;  3TVC A;  3F19 A;  2V4B A;  1JAN A;  3LMC A;  1YOU A;  1MMR A;  4DF9 A;  1L6J A;  2DW1 A;  3NX7 A;  1GE6 A;  1JIW P;  3HY9 A;  4JIJ A;  4I35 A;  2OW2 A;  1BUD A;  3LJT A;  2JIH A;  4JP4 A;  1SMP A;  3KMC A;  3MA2 A;  2OW9 A;  4HX3 A;  1B3D A;  1XUR A;  2W15 A;  1H71 P;  3AYK A;  1BKC I;  3DNG A;  1OO9 A;  1XFZ A;  1JH1 A;  1GO8 P;  1QIA A;  4IN9 A;  4XM6 A;  1EUB A;  2WOA A;  1JAO A;  1AKL A;  2RJQ A;  3F15 A;  3HYG A;  3CKI A;  4JPA A;  4GQL A;  4XBH A;  1XUC A;  4L63 A;  3F18 A;  1Q3A A;  2DDF A;  1SU3 A;  3L0T A;  1QJJ A;  5D1S A;  1I73 A;  3LEA A;  4FU4 A;  1ATL A;  3Q2H A;  2OVX A;  3B2Z A;  4AIG A;  1JIZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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