2JC4A

3'-5' exonuclease (nexo) from neisseria meningitidis
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
256
structure length
256
Chain Sequence
MKITTWNVNSLNVRLPQVQNLLADNPPDILVLQELKLDQDKFPAAALQMMGWHCVWSGQKTYNGVAIVSRSVPQDVHFGLPALPDDPQRRVIAATVSGVRVINVYCVNGEALDSPKFKYKEQWFAALTEFVRDEMTRHGKLVLLGDFNIAPADADCYDPEKWHEKIHCSSVERQWFQNLLDLGLTDSLRQVHPEGAFYTWFDYRGAMFQRKLGLRIDHILVSPAMAAALKDVRVDLETRALERPSDHAPVTAEFDW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Ap Endonuclease Paralogues with Distinct Activities in DNA Repair and Bacterial Pathogenesis.
pubmed doi rcsb
molecule tags Hydrolase
source organism Neisseria meningitidis
molecule keywords EXODEOXYRIBONUCLEASE III
total genus 91
structure length 256
sequence length 256
ec nomenclature ec 3.1.11.2: Exodeoxyribonuclease III.
pdb deposition date 2006-12-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 2jc4A00
1BIXA 2EI9A 5A7IA 3U8UA 2V0SA 5INOA 4GZ1A 2ISIA 3W2YA 5DFFA 5INNA 1DNKA 2DDSA 5INKA 3G00A 2J63A 4B5HA 4B5MA 4QHEA 3G1KA 3K55A 1I9ZA 3NR8A 2O3CA 3L1WA 3I46A 3G6SA 5J3SA 2V0RA 3MTCA 2JC4A 5CFGA 3NGNA 1YJHA 3G3CA 4QHDA 5HT2A 4B5FA 3NGOA 4GEWA 4C1RA 3WCXA 5INMA 4AWNA 5DFIA 4K6LF 3G2CA 2D1KB 3N9VA 2A42B 1DE8A 4RUWA 3G3YA 4L1YA 5DFHA 4PUQA 3G0RA 1SI6X 2JC5A 1NTFA 3I41A 3DNIA 4QH9A 1DE9A 5INPA 3G0AA 4B5GA 4F1HB 1I9YA 5DFJA 4CMLA 5DV4A 1E9NA 2XSWA 4B5IA 1Y21A 1AKOA 4IEMA 4A9CA 5CFEA 4L20A 1ATND 2DNJA 3NGQA 1WDUA 2A3ZB 4JG3A 1ZWXA 4GZ2A 4GYZA 3W2XA 4FVAA 2A40B 2DDRA 1SR4B 3I48A 4L21A 1DEWA 4L1ZA 3MPRA 5INLA 3W3DB 5EWTA 3G4TA 2O3HA 2F2FB 3G91A 3TEBA 2A41B 2DDTA 2F1NA 3I5VA 2VOAA 5A7JA 5J8NA 4LNDA 5J42A 4F1IA 3FZIA 4FPVA 5J3PA 4GZ0A 3G8VA 2UYRX 3G38A 5DG0A 1HD7A 5DV2A 3G2DA 4B5JA 4F1RA 4CMNA 5J3ZA 1VYBA 2IMQX 5INQA 4F1HA 3GA6A 3CJCD
chains in the Genus database with same CATH superfamily
1BIXA 2EI9A 5A7IA 3U8UA 2V0SA 5INOA 4GZ1A 2ISIA 3W2YA 5DFFA 5INNA 1DNKA 2DDSA 5INKA 3G00A 2J63A 4B5HA 4B5MA 4QHEA 3G1KA 3K55A 1I9ZA 3NR8A 2O3CA 3L1WA 3I46A 3G6SA 5J3SA 2V0RA 3MTCA 2JC4A 5CFGA 3NGNA 1YJHA 3G3CA 4QHDA 5HT2A 4B5FA 3NGOA 4GEWA 4C1RA 3WCXA 5INMA 4AWNA 5DFIA 4K6LF 3G2CA 2D1KB 3N9VA 2A42B 1DE8A 4RUWA 3G3YA 4L1YA 5DFHA 4PUQA 3G0RA 1SI6X 2JC5A 1NTFA 3I41A 3DNIA 4QH9A 1DE9A 5INPA 3G0AA 4B5GA 4F1HB 1I9YA 5DFJA 4CMLA 5DV4A 1E9NA 2XSWA 4B5IA 1Y21A 1AKOA 4IEMA 4A9CA 5CFEA 4L20A 1ATND 2DNJA 3NGQA 1WDUA 2A3ZB 4JG3A 1ZWXA 4GZ2A 4GYZA 3W2XA 4FVAA 2A40B 2DDRA 1SR4B 3I48A 4L21A 1DEWA 4L1ZA 3MPRA 5INLA 3W3DB 5EWTA 3G4TA 2O3HA 2F2FB 3G91A 3TEBA 2A41B 2DDTA 2F1NA 3I5VA 2VOAA 5A7JA 5J8NA 4LNDA 5J42A 4F1IA 3FZIA 4FPVA 5J3PA 4GZ0A 3G8VA 2UYRX 3G38A 5DG0A 1HD7A 5DV2A 3G2DA 4B5JA 4F1RA 4CMNA 5J3ZA 1VYBA 2IMQX 5INQA 4F1HA 3GA6A 3CJCD
chains in the Genus database with same CATH topology
1BIXA 2EI9A 5A7IA 3U8UA 2V0SA 5INOA 4GZ1A 2ISIA 3W2YA 5DFFA 5INNA 1DNKA 2DDSA 5INKA 3G00A 2J63A 4B5HA 4B5MA 4QHEA 3G1KA 3K55A 1I9ZA 3NR8A 2O3CA 3L1WA 3I46A 3G6SA 5J3SA 2V0RA 3MTCA 2JC4A 5CFGA 3NGNA 1YJHA 3G3CA 4QHDA 5HT2A 4B5FA 3NGOA 4GEWA 4C1RA 3WCXA 5INMA 4AWNA 5DFIA 4K6LF 3G2CA 2D1KB 3N9VA 2A42B 1DE8A 4RUWA 3G3YA 4L1YA 5DFHA 4PUQA 3G0RA 1SI6X 2JC5A 1NTFA 3I41A 3DNIA 4QH9A 1DE9A 5INPA 3G0AA 4B5GA 4F1HB 1I9YA 5DFJA 4CMLA 5DV4A 1E9NA 2XSWA 4B5IA 1Y21A 1AKOA 4IEMA 4A9CA 5CFEA 4L20A 1ATND 2DNJA 3NGQA 1WDUA 2A3ZB 4JG3A 1ZWXA 4GZ2A 4GYZA 3W2XA 4FVAA 2A40B 2DDRA 1SR4B 3I48A 4L21A 1DEWA 4L1ZA 3MPRA 5INLA 3W3DB 5EWTA 3G4TA 2O3HA 2F2FB 3G91A 3TEBA 2A41B 2DDTA 2F1NA 3I5VA 2VOAA 5A7JA 5J8NA 4LNDA 5J42A 4F1IA 3FZIA 4FPVA 5J3PA 4GZ0A 3G8VA 2UYRX 3G38A 5DG0A 1HD7A 5DV2A 3G2DA 4B5JA 4F1RA 4CMNA 5J3ZA 1VYBA 2IMQX 5INQA 4F1HA 3GA6A 3CJCD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BIX A;  2EI9 A;  5A7I A;  3U8U A;  2V0S A;  5INO A;  4GZ1 A;  2ISI A;  3W2Y A;  5DFF A;  5INN A;  1DNK A;  2DDS A;  5INK A;  3G00 A;  2J63 A;  4B5H A;  4B5M A;  4QHE A;  3G1K A;  3K55 A;  1I9Z A;  3NR8 A;  2O3C A;  3L1W A;  3I46 A;  3G6S A;  5J3S A;  2V0R A;  3MTC A;  2JC4 A;  5CFG A;  3NGN A;  1YJH A;  3G3C A;  4QHD A;  5HT2 A;  4B5F A;  3NGO A;  4GEW A;  4C1R A;  3WCX A;  5INM A;  4AWN A;  5DFI A;  4K6L F;  3G2C A;  2D1K B;  3N9V A;  2A42 B;  1DE8 A;  4RUW A;  3G3Y A;  4L1Y A;  5DFH A;  4PUQ A;  3G0R A;  1SI6 X;  2JC5 A;  1NTF A;  3I41 A;  3DNI A;  4QH9 A;  1DE9 A;  5INP A;  3G0A A;  4B5G A;  4F1H B;  1I9Y A;  5DFJ A;  4CML A;  5DV4 A;  1E9N A;  2XSW A;  4B5I A;  1Y21 A;  1AKO A;  4IEM A;  4A9C A;  5CFE A;  4L20 A;  1ATN D;  2DNJ A;  3NGQ A;  1WDU A;  2A3Z B;  4JG3 A;  1ZWX A;  4GZ2 A;  4GYZ A;  3W2X A;  4FVA A;  2A40 B;  2DDR A;  1SR4 B;  3I48 A;  4L21 A;  1DEW A;  4L1Z A;  3MPR A;  5INL A;  3W3D B;  5EWT A;  3G4T A;  2O3H A;  2F2F B;  3G91 A;  3TEB A;  2A41 B;  2DDT A;  2F1N A;  3I5V A;  2VOA A;  5A7J A;  5J8N A;  4LND A;  5J42 A;  4F1I A;  3FZI A;  4FPV A;  5J3P A;  4GZ0 A;  3G8V A;  2UYR X;  3G38 A;  5DG0 A;  1HD7 A;  5DV2 A;  3G2D A;  4B5J A;  4F1R A;  4CMN A;  5J3Z A;  1VYB A;  2IMQ X;  5INQ A;  4F1H A;  3GA6 A;  3CJC D; 
#chains in the Genus database with same CATH topology
 1BIX A;  2EI9 A;  5A7I A;  3U8U A;  2V0S A;  5INO A;  4GZ1 A;  2ISI A;  3W2Y A;  5DFF A;  5INN A;  1DNK A;  2DDS A;  5INK A;  3G00 A;  2J63 A;  4B5H A;  4B5M A;  4QHE A;  3G1K A;  3K55 A;  1I9Z A;  3NR8 A;  2O3C A;  3L1W A;  3I46 A;  3G6S A;  5J3S A;  2V0R A;  3MTC A;  2JC4 A;  5CFG A;  3NGN A;  1YJH A;  3G3C A;  4QHD A;  5HT2 A;  4B5F A;  3NGO A;  4GEW A;  4C1R A;  3WCX A;  5INM A;  4AWN A;  5DFI A;  4K6L F;  3G2C A;  2D1K B;  3N9V A;  2A42 B;  1DE8 A;  4RUW A;  3G3Y A;  4L1Y A;  5DFH A;  4PUQ A;  3G0R A;  1SI6 X;  2JC5 A;  1NTF A;  3I41 A;  3DNI A;  4QH9 A;  1DE9 A;  5INP A;  3G0A A;  4B5G A;  4F1H B;  1I9Y A;  5DFJ A;  4CML A;  5DV4 A;  1E9N A;  2XSW A;  4B5I A;  1Y21 A;  1AKO A;  4IEM A;  4A9C A;  5CFE A;  4L20 A;  1ATN D;  2DNJ A;  3NGQ A;  1WDU A;  2A3Z B;  4JG3 A;  1ZWX A;  4GZ2 A;  4GYZ A;  3W2X A;  4FVA A;  2A40 B;  2DDR A;  1SR4 B;  3I48 A;  4L21 A;  1DEW A;  4L1Z A;  3MPR A;  5INL A;  3W3D B;  5EWT A;  3G4T A;  2O3H A;  2F2F B;  3G91 A;  3TEB A;  2A41 B;  2DDT A;  2F1N A;  3I5V A;  2VOA A;  5A7J A;  5J8N A;  4LND A;  5J42 A;  4F1I A;  3FZI A;  4FPV A;  5J3P A;  4GZ0 A;  3G8V A;  2UYR X;  3G38 A;  5DG0 A;  1HD7 A;  5DV2 A;  3G2D A;  4B5J A;  4F1R A;  4CMN A;  5J3Z A;  1VYB A;  2IMQ X;  5INQ A;  4F1H A;  3GA6 A;  3CJC D; 
#chains in the Genus database with same CATH homology
 1BIX A;  2EI9 A;  5A7I A;  3U8U A;  2V0S A;  5INO A;  4GZ1 A;  2ISI A;  3W2Y A;  5DFF A;  5INN A;  1DNK A;  2DDS A;  5INK A;  3G00 A;  2J63 A;  4B5H A;  4B5M A;  4QHE A;  3G1K A;  3K55 A;  1I9Z A;  3NR8 A;  2O3C A;  3L1W A;  3I46 A;  3G6S A;  5J3S A;  2V0R A;  3MTC A;  2JC4 A;  5CFG A;  3NGN A;  1YJH A;  3G3C A;  4QHD A;  5HT2 A;  4B5F A;  3NGO A;  4GEW A;  4C1R A;  3WCX A;  5INM A;  4AWN A;  5DFI A;  4K6L F;  3G2C A;  2D1K B;  3N9V A;  2A42 B;  1DE8 A;  4RUW A;  3G3Y A;  4L1Y A;  5DFH A;  4PUQ A;  3G0R A;  1SI6 X;  2JC5 A;  1NTF A;  3I41 A;  3DNI A;  4QH9 A;  1DE9 A;  5INP A;  3G0A A;  4B5G A;  4F1H B;  1I9Y A;  5DFJ A;  4CML A;  5DV4 A;  1E9N A;  2XSW A;  4B5I A;  1Y21 A;  1AKO A;  4IEM A;  4A9C A;  5CFE A;  4L20 A;  1ATN D;  2DNJ A;  3NGQ A;  1WDU A;  2A3Z B;  4JG3 A;  1ZWX A;  4GZ2 A;  4GYZ A;  3W2X A;  4FVA A;  2A40 B;  2DDR A;  1SR4 B;  3I48 A;  4L21 A;  1DEW A;  4L1Z A;  3MPR A;  5INL A;  3W3D B;  5EWT A;  3G4T A;  2O3H A;  2F2F B;  3G91 A;  3TEB A;  2A41 B;  2DDT A;  2F1N A;  3I5V A;  2VOA A;  5A7J A;  5J8N A;  4LND A;  5J42 A;  4F1I A;  3FZI A;  4FPV A;  5J3P A;  4GZ0 A;  3G8V A;  2UYR X;  3G38 A;  5DG0 A;  1HD7 A;  5DV2 A;  3G2D A;  4B5J A;  4F1R A;  4CMN A;  5J3Z A;  1VYB A;  2IMQ X;  5INQ A;  4F1H A;  3GA6 A;  3CJC D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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