2JC5A

Apurinic apyrimidinic (ap) endonuclease (nape) from neisseria meningitidis
Total Genus 83
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
83
sequence length
259
structure length
259
Chain Sequence
MLKIISANVNGIRSAYKKGFYEYIAASGADIVCVQELKAQEADLSADMKNPHGMHGHWHCAEKRGYSGVAVYSKRKPDNVQIGMGIEEFDREGRFVRCDFGRLSVISLYLPSGSSAEERQQVKYRFLDAFYPMLEAMKNEGRDIVVCGDWNIAHQNIDLKNWKGNQKNSGFLPEEREWIGKVIHKLGWTDMWRTLYPDVPGYTWWSNRGQAYAKDVGWRIDYQMVTPELAAKAVSAHVYKDEKFSDHAPLVVEYDYAAE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Ap Endonuclease Paralogues with Distinct Activities in DNA Repair and Bacterial Pathogenesis.
pubmed doi rcsb
molecule tags Hydrolase
source organism Neisseria meningitidis
molecule keywords EXODEOXYRIBONUCLEASE
total genus 83
structure length 259
sequence length 259
ec nomenclature ec 3.1.11.2: Exodeoxyribonuclease III.
pdb deposition date 2006-12-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 2jc5A00
3K55A 3G6SA 3TEBA 2JC5A 5DFHA 5CFEA 3MTCA 2O3CA 5DG0A 3I41A 3NGOA 2DDRA 4L20A 5J3PA 3NGNA 3G4TA 3NGQA 4B5FA 2JC4A 5INNA 2J63A 2F2FB 3WCXA 5INQA 5J42A 5INMA 3W2YA 3I48A 4QHEA 3G0RA 3G0AA 4B5GA 3G8VA 4B5IA 4L21A 4GEWA 1BIXA 4GYZA 4IEMA 4QH9A 3G1KA 1SI6X 1VYBA 4F1HA 3G3YA 2IMQX 2DNJA 2ISIA 3G91A 5J3SA 4CMNA 5INOA 2DDSA 5J3ZA 4LNDA 1E9NA 5DV4A 5INKA 1SR4B 5INLA 1DNKA 3U8UA 2UYRX 1AKOA 2A41B 5DV2A 3G2CA 2XSWA 4L1ZA 1I9ZA 5A7IA 1DE8A 5A7JA 2A40B 3G2DA 2A3ZB 1WDUA 3N9VA 1ZWXA 4C1RA 3G38A 5J8NA 3FZIA 4FVAA 5CFGA 4B5HA 2D1KB 1ATND 4L1YA 4F1HB 4A9CA 2VOAA 5DFIA 2F1NA 3L1WA 4QHDA 4AWNA 4F1IA 3W3DB 3NR8A 2O3HA 5DFJA 3G00A 2A42B 5HT2A 4CMLA 4PUQA 2V0SA 4JG3A 4F1RA 1I9YA 1NTFA 1DE9A 2EI9A 3G3CA 2DDTA 4RUWA 4B5MA 4GZ0A 4GZ2A 3I46A 4K6LF 1Y21A 3GA6A 3DNIA 3I5VA 3W2XA 1YJHA 2V0RA 1DEWA 3MPRA 4B5JA 5DFFA 5INPA 4GZ1A 1HD7A 3CJCD 5EWTA 4FPVA
chains in the Genus database with same CATH superfamily
3K55A 3G6SA 3TEBA 2JC5A 5DFHA 5CFEA 3MTCA 2O3CA 5DG0A 3I41A 3NGOA 2DDRA 4L20A 5J3PA 3NGNA 3G4TA 3NGQA 4B5FA 2JC4A 5INNA 2J63A 2F2FB 3WCXA 5INQA 5J42A 5INMA 3W2YA 3I48A 4QHEA 3G0RA 3G0AA 4B5GA 3G8VA 4B5IA 4L21A 4GEWA 1BIXA 4GYZA 4IEMA 4QH9A 3G1KA 1SI6X 1VYBA 4F1HA 3G3YA 2IMQX 2DNJA 2ISIA 3G91A 5J3SA 4CMNA 5INOA 2DDSA 5J3ZA 4LNDA 1E9NA 5DV4A 5INKA 1SR4B 5INLA 1DNKA 3U8UA 2UYRX 1AKOA 2A41B 5DV2A 3G2CA 2XSWA 4L1ZA 1I9ZA 5A7IA 1DE8A 5A7JA 2A40B 3G2DA 2A3ZB 1WDUA 3N9VA 1ZWXA 4C1RA 3G38A 5J8NA 3FZIA 4FVAA 5CFGA 4B5HA 2D1KB 1ATND 4L1YA 4F1HB 4A9CA 2VOAA 5DFIA 2F1NA 3L1WA 4QHDA 4AWNA 4F1IA 3W3DB 3NR8A 2O3HA 5DFJA 3G00A 2A42B 5HT2A 4CMLA 4PUQA 2V0SA 4JG3A 4F1RA 1I9YA 1NTFA 1DE9A 2EI9A 3G3CA 2DDTA 4RUWA 4B5MA 4GZ0A 4GZ2A 3I46A 4K6LF 1Y21A 3GA6A 3DNIA 3I5VA 3W2XA 1YJHA 2V0RA 1DEWA 3MPRA 4B5JA 5DFFA 5INPA 4GZ1A 1HD7A 3CJCD 5EWTA 4FPVA
chains in the Genus database with same CATH topology
3K55A 3G6SA 3TEBA 2JC5A 5DFHA 5CFEA 3MTCA 2O3CA 5DG0A 3I41A 3NGOA 2DDRA 4L20A 5J3PA 3NGNA 3G4TA 3NGQA 4B5FA 2JC4A 5INNA 2J63A 2F2FB 3WCXA 5INQA 5J42A 5INMA 3W2YA 3I48A 4QHEA 3G0RA 3G0AA 4B5GA 3G8VA 4B5IA 4L21A 4GEWA 1BIXA 4GYZA 4IEMA 4QH9A 3G1KA 1SI6X 1VYBA 4F1HA 3G3YA 2IMQX 2DNJA 2ISIA 3G91A 5J3SA 4CMNA 5INOA 2DDSA 5J3ZA 4LNDA 1E9NA 5DV4A 5INKA 1SR4B 5INLA 1DNKA 3U8UA 2UYRX 1AKOA 2A41B 5DV2A 3G2CA 2XSWA 4L1ZA 1I9ZA 5A7IA 1DE8A 5A7JA 2A40B 3G2DA 2A3ZB 1WDUA 3N9VA 1ZWXA 4C1RA 3G38A 5J8NA 3FZIA 4FVAA 5CFGA 4B5HA 2D1KB 1ATND 4L1YA 4F1HB 4A9CA 2VOAA 5DFIA 2F1NA 3L1WA 4QHDA 4AWNA 4F1IA 3W3DB 3NR8A 2O3HA 5DFJA 3G00A 2A42B 5HT2A 4CMLA 4PUQA 2V0SA 4JG3A 4F1RA 1I9YA 1NTFA 1DE9A 2EI9A 3G3CA 2DDTA 4RUWA 4B5MA 4GZ0A 4GZ2A 3I46A 4K6LF 1Y21A 3GA6A 3DNIA 3I5VA 3W2XA 1YJHA 2V0RA 1DEWA 3MPRA 4B5JA 5DFFA 5INPA 4GZ1A 1HD7A 3CJCD 5EWTA 4FPVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3K55 A;  3G6S A;  3TEB A;  2JC5 A;  5DFH A;  5CFE A;  3MTC A;  2O3C A;  5DG0 A;  3I41 A;  3NGO A;  2DDR A;  4L20 A;  5J3P A;  3NGN A;  3G4T A;  3NGQ A;  4B5F A;  2JC4 A;  5INN A;  2J63 A;  2F2F B;  3WCX A;  5INQ A;  5J42 A;  5INM A;  3W2Y A;  3I48 A;  4QHE A;  3G0R A;  3G0A A;  4B5G A;  3G8V A;  4B5I A;  4L21 A;  4GEW A;  1BIX A;  4GYZ A;  4IEM A;  4QH9 A;  3G1K A;  1SI6 X;  1VYB A;  4F1H A;  3G3Y A;  2IMQ X;  2DNJ A;  2ISI A;  3G91 A;  5J3S A;  4CMN A;  5INO A;  2DDS A;  5J3Z A;  4LND A;  1E9N A;  5DV4 A;  5INK A;  1SR4 B;  5INL A;  1DNK A;  3U8U A;  2UYR X;  1AKO A;  2A41 B;  5DV2 A;  3G2C A;  2XSW A;  4L1Z A;  1I9Z A;  5A7I A;  1DE8 A;  5A7J A;  2A40 B;  3G2D A;  2A3Z B;  1WDU A;  3N9V A;  1ZWX A;  4C1R A;  3G38 A;  5J8N A;  3FZI A;  4FVA A;  5CFG A;  4B5H A;  2D1K B;  1ATN D;  4L1Y A;  4F1H B;  4A9C A;  2VOA A;  5DFI A;  2F1N A;  3L1W A;  4QHD A;  4AWN A;  4F1I A;  3W3D B;  3NR8 A;  2O3H A;  5DFJ A;  3G00 A;  2A42 B;  5HT2 A;  4CML A;  4PUQ A;  2V0S A;  4JG3 A;  4F1R A;  1I9Y A;  1NTF A;  1DE9 A;  2EI9 A;  3G3C A;  2DDT A;  4RUW A;  4B5M A;  4GZ0 A;  4GZ2 A;  3I46 A;  4K6L F;  1Y21 A;  3GA6 A;  3DNI A;  3I5V A;  3W2X A;  1YJH A;  2V0R A;  1DEW A;  3MPR A;  4B5J A;  5DFF A;  5INP A;  4GZ1 A;  1HD7 A;  3CJC D;  5EWT A;  4FPV A; 
#chains in the Genus database with same CATH topology
 3K55 A;  3G6S A;  3TEB A;  2JC5 A;  5DFH A;  5CFE A;  3MTC A;  2O3C A;  5DG0 A;  3I41 A;  3NGO A;  2DDR A;  4L20 A;  5J3P A;  3NGN A;  3G4T A;  3NGQ A;  4B5F A;  2JC4 A;  5INN A;  2J63 A;  2F2F B;  3WCX A;  5INQ A;  5J42 A;  5INM A;  3W2Y A;  3I48 A;  4QHE A;  3G0R A;  3G0A A;  4B5G A;  3G8V A;  4B5I A;  4L21 A;  4GEW A;  1BIX A;  4GYZ A;  4IEM A;  4QH9 A;  3G1K A;  1SI6 X;  1VYB A;  4F1H A;  3G3Y A;  2IMQ X;  2DNJ A;  2ISI A;  3G91 A;  5J3S A;  4CMN A;  5INO A;  2DDS A;  5J3Z A;  4LND A;  1E9N A;  5DV4 A;  5INK A;  1SR4 B;  5INL A;  1DNK A;  3U8U A;  2UYR X;  1AKO A;  2A41 B;  5DV2 A;  3G2C A;  2XSW A;  4L1Z A;  1I9Z A;  5A7I A;  1DE8 A;  5A7J A;  2A40 B;  3G2D A;  2A3Z B;  1WDU A;  3N9V A;  1ZWX A;  4C1R A;  3G38 A;  5J8N A;  3FZI A;  4FVA A;  5CFG A;  4B5H A;  2D1K B;  1ATN D;  4L1Y A;  4F1H B;  4A9C A;  2VOA A;  5DFI A;  2F1N A;  3L1W A;  4QHD A;  4AWN A;  4F1I A;  3W3D B;  3NR8 A;  2O3H A;  5DFJ A;  3G00 A;  2A42 B;  5HT2 A;  4CML A;  4PUQ A;  2V0S A;  4JG3 A;  4F1R A;  1I9Y A;  1NTF A;  1DE9 A;  2EI9 A;  3G3C A;  2DDT A;  4RUW A;  4B5M A;  4GZ0 A;  4GZ2 A;  3I46 A;  4K6L F;  1Y21 A;  3GA6 A;  3DNI A;  3I5V A;  3W2X A;  1YJH A;  2V0R A;  1DEW A;  3MPR A;  4B5J A;  5DFF A;  5INP A;  4GZ1 A;  1HD7 A;  3CJC D;  5EWT A;  4FPV A; 
#chains in the Genus database with same CATH homology
 3K55 A;  3G6S A;  3TEB A;  2JC5 A;  5DFH A;  5CFE A;  3MTC A;  2O3C A;  5DG0 A;  3I41 A;  3NGO A;  2DDR A;  4L20 A;  5J3P A;  3NGN A;  3G4T A;  3NGQ A;  4B5F A;  2JC4 A;  5INN A;  2J63 A;  2F2F B;  3WCX A;  5INQ A;  5J42 A;  5INM A;  3W2Y A;  3I48 A;  4QHE A;  3G0R A;  3G0A A;  4B5G A;  3G8V A;  4B5I A;  4L21 A;  4GEW A;  1BIX A;  4GYZ A;  4IEM A;  4QH9 A;  3G1K A;  1SI6 X;  1VYB A;  4F1H A;  3G3Y A;  2IMQ X;  2DNJ A;  2ISI A;  3G91 A;  5J3S A;  4CMN A;  5INO A;  2DDS A;  5J3Z A;  4LND A;  1E9N A;  5DV4 A;  5INK A;  1SR4 B;  5INL A;  1DNK A;  3U8U A;  2UYR X;  1AKO A;  2A41 B;  5DV2 A;  3G2C A;  2XSW A;  4L1Z A;  1I9Z A;  5A7I A;  1DE8 A;  5A7J A;  2A40 B;  3G2D A;  2A3Z B;  1WDU A;  3N9V A;  1ZWX A;  4C1R A;  3G38 A;  5J8N A;  3FZI A;  4FVA A;  5CFG A;  4B5H A;  2D1K B;  1ATN D;  4L1Y A;  4F1H B;  4A9C A;  2VOA A;  5DFI A;  2F1N A;  3L1W A;  4QHD A;  4AWN A;  4F1I A;  3W3D B;  3NR8 A;  2O3H A;  5DFJ A;  3G00 A;  2A42 B;  5HT2 A;  4CML A;  4PUQ A;  2V0S A;  4JG3 A;  4F1R A;  1I9Y A;  1NTF A;  1DE9 A;  2EI9 A;  3G3C A;  2DDT A;  4RUW A;  4B5M A;  4GZ0 A;  4GZ2 A;  3I46 A;  4K6L F;  1Y21 A;  3GA6 A;  3DNI A;  3I5V A;  3W2X A;  1YJH A;  2V0R A;  1DEW A;  3MPR A;  4B5J A;  5DFF A;  5INP A;  4GZ1 A;  1HD7 A;  3CJC D;  5EWT A;  4FPV A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...