2JHNA

3-methyladenine dna-glycosylase from archaeoglobus fulgidus
Total Genus 103
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
103
sequence length
295
structure length
293
Chain Sequence
MWRIELKHAVNWELKMKFFVLPELPTPDVVESGVWRRAIVLDGRAVAVMAYPESERTIVVEGNFENREWEAVRRKLVEYLGLQNPEELYRFMDGDEKLRMLKNRFYGFGRAGLMSMSVFEGIAKAIIQQQISFVVAEKLAAKIVGRFGDEVEWNGLKFYGFPTQEAILKAGVEGLRECGLSRRKAELIVEIAKEENLEELKEWGEEEAYEYLTSFKGIGRWTAELVLSIALGKNVFPADDLGVRRAVSRLYFNGEIQSAEKVREIARERFGRFARDILFYLFLYDRFFSKELV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Enzymatic Excision of N1-Methyladenine and N3-Methylcytosine from DNA
pubmed doi rcsb
molecule tags Hydrolase
source organism Archaeoglobus fulgidus
molecule keywords 3-METHYLADENINE DNA-GLYCOSYLASE
total genus 103
structure length 293
sequence length 295
chains with identical sequence B
ec nomenclature ec 3.2.2.21: DNA-3-methyladenine glycosylase II.
pdb deposition date 2007-02-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 2jhnA02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 2jhnA03
3.30.310.20 Alpha Beta 2-Layer Sandwich TATA-Binding Protein DNA-3-methyladenine glycosylase AlkA, N-terminal domain 2jhnA01
1YQKA 1ORPA 1N3CA 2ABKA 4EJZA 1XQPA 3CVSA 1PU8A 3IH7A 1FN7A 1MPGA 1PU6A 1WEFA 1HU0A 2JHJA 4UOBA 1WEGA 4EA5A 1NKUA 3S6IA 4OFHA 1YQLA 1N3AA 3CVTA 1VRLA 2OFIA 1MUNA 3FHFA 5KN9A 4B24A 5CHZA 3CWAA 4OFAA 2NOHA 3N5NX 1RRSA 3OH9A 1M3HA 3N0UA 1PU7A 1LWVA 2JHNA 4EJYA 4EVVA 2NOZA 5AN4A 4B21A 4OFEA 1RRQA 2NOFA 4DK9A 1LMZA 1M3QA 1P7MA 1KG5A 2JG6A 3KTUA 4UNFA 3CWUA 4EW4A 4AIAA 4EW0A 4PIIA 4AI5A 1MUYA 1N39A 4E9HA 1PVSA 5KN8A 4YPHA 4AI4A 3OGDA 3CW7A 2XHIA 4YPRA 3OH6A 1XG7A 2NOBA 2OFKA 3IHOA 1XQOA 3CWSA 1KG6A 2H56A 4HSBA 5DPKA 4E9GA 2NOIA 4E9FA 2YG9A 3F10A 1WEIA 2NOLA 1LWYA 1ORNA 3I0WA 2YG8A 1KG3A 1NGNA 4YOQA 1EBMA 3FHGA 3I0XA 2I5WA 1MUDA 1KO9A 1LWWA 3G0QA 1KEAA 3CWTA 1KG7A 1KG4A 4B23A 4EA4A 4E9EA 3D4VA 3FSPA 1KQJA 4B22A 1YQRA 1YQMA 1P59A 3KNTA 3F0ZA 1DIZA 1KG2A 2NOEA
chains in the Genus database with same CATH superfamily
2D0CA 3NNQA 1N3CA 3TE5A 3IH7A 1FN7A 1EUVA 3OYDA 2JHJA 4RODB 4UOBA 4EA5A 1NKUA 1YQLA 3OYKA 1N3AA 2Z8UA 3OYAA 1MUNA 1PCMX 2NOHA 3N5NX 2Z0FA 3OH9A 1M3HA 3N0UA 2NOZA 2Y8LA 1VTOA 1B9KA 3OSEA 3OLPA 1LMZA 5IYBP 4ROCB 2JOIA 1KG5A 2JG6A 3KTUA 1JDYA 2H4LX 4Q11A 2QRCA 3OS0A 1MUYA 3OS2A 2HKPA 2F7LA 2XHIA 4YPRA 3L2VA 2HZMA 3IHOA 5F9CA 4HSBA 3ENOC 3I3WA 1M5Q1 1K35A 4BACA 1PZDA 4PY5A 1TBAB 3VN5A 4IL8A 3FHGA 5BMPA 2I5WA 1QNBA 1LWWA 2IV8A 3LCNA 2OOXA 2Y8QA 3FSPA 4ZTFA 1YQMA 3F0ZA 1DIZA 3N89A 1YTBA 4BDYA 2NOEA 3KRMA 1YQKA 1ORPA 1XQPA 3CVSA 2HL9A 4EAKA 1PU6A 1QN8A 3D7QA 2YA3A 3NA5A 1QN9A 3PMGA 3C04A 5KN9A 4OFAA 3CWAA 4EAIA 1K2YX 3ASMA 3RPJA 1C47A 4EVVA 3SNSA 1RM1A 1AISA 1C9BB 2NOFA 4DK9A 1M3QA 2V8QA 5EPCA 3EAYA 1NVPA 2FKMX 1TUOA 3OYIA 3OYEA 1W80A 4B0AA 5FRMA 4EW0A 4AI5A 1NGMA 4E7LA 1N39A 1WQAA 3S3OA 4E7JA 4E7HA 3CW7A 1T6AA 1QNEA 4EALA 4BDZA 1XQOA 3CWSA 1XSZA 1KYDA 4E9FA 2YG9A 3F10A 3DPUA 1LWYA 3OSTA 3PDKA 3L2QA 1QN6A 1QN5A 2FUVA 1KG3A 4ROEB 1NGNA 4YOQA 1EBMA 4D7RA 1VTLE 1MUDA 4BE0A 1P5GX 1KO9A 3G0QA 3OYHA 4E9EA 1VKLA 4B22A 1PCZA 4E7IA 2DKDA 4I8OA 3L2UA 2IV9A 1CDWA 2O3OA 4EJZA 1E42A 1PCJX 1WJWA 5JN5A 1WEFA 1WEGA 2D0BA 2D0AA 1KY6A 3S6IA 5FROA 4NZGA 2PWWA 3FHFA 2JPSA 5CHZA 4IKFA 1JFIC 2W03A 2JHNA 1VOKA 4BJUA 2ZFDB 5AN4A 4B21A 1RRQA 3OYJA 4WX8A 1QTSA 4UNFA 4EW4A 2HZSA 1NH2A 1KY7A 2R5XA 1PVSA 4BE1A 3HS8A 5KN8A 3OYNA 4AI4A 2JPIA 3R2XC 3OGDA 1VOLB 3OH6A 2NOBA 3S3MA 1C4GA 2VJ0A 2OFKA 1D3UA 1KG6A 1TBPA 3OY9A 2H56A 2FGTA 2MJ7A 2NOIA 3BKQX 3HS9A 1WEIA 3EIKA 3TDHA 2V9JA 3OYCA 2NOLA 3OYFA 2MZ8A 1ORNA 3I0WA 1QNAA 1KYFA 4C7PA 2V92A 1QNCA 2QREA 1KEAA 1KG7A 4B23A 1UT4A 4EA4A 5IYDP 1MP9A 3D4VA 1QTPA 5BMNA 3UW2A 1YQRA 1P59A 4EAJA 4TPSA 2QLVA 3DPTA 1KG2A 1UL7A 2ABKA 1PU8A 3ULXA 2NVMA 2NWVA 1MPGA 1HU0A 2W04A 3T4NA 3OS1A 4HJHA 3VW4A 1UT7A 4OFHA 4BE2A 3CVTA 1VRLA 2OFIA 2YH5A 1KYUA 5HSHA 2QRDA 3OYLA 4B24A 4QG5A 2DKCA 5KL0A 1RRSA 4WZSD 1J3MA 1QN4A 1PU7A 1LWVA 1LXTA 3H1ZA 4EJYA 4DULA 2EHBD 1QN3A 2QR1A 3OSMA 4OFEA 2OOYA 3OYBA 1YTFA 1U84A 4EAGA 1P7MA 2H5AX 3CWUA 4D7QA 1TGHA 4AIAA 3OC3C 4PIIA 1V5SA 4E9HA 1Q9UA 2NLVA 1P5DX 4YPHA 2V75A 1XG7A 5FRNA 1QN7A 5IYCP 3L2RA 4CFFA 5DPKA 5JMVD 4E9GA 2HL8A 1KFIA 3L2WA 1KFQA 3RSMA 4E7KA 2YG8A 2DKAA 2LAEA 4ZTJA 3I0XA 3OYMA 1R4XA 3OCIA 3CWTA 1KG4A 2G30A 1KQJA 3S3NA 3KNTA 2FKFA 3ENCA 3OYGA 4WXAA 4MRQA
chains in the Genus database with same CATH topology
1YQKA 1ORPA 1N3CA 2ABKA 4EJZA 1XQPA 3CVSA 1PU8A 3IH7A 1FN7A 1MPGA 1PU6A 1WEFA 1HU0A 2JHJA 4UOBA 1WEGA 4EA5A 1NKUA 3S6IA 4OFHA 1YQLA 1N3AA 3CVTA 1VRLA 2OFIA 1MUNA 3FHFA 5KN9A 4B24A 5CHZA 3CWAA 4OFAA 2NOHA 3N5NX 1RRSA 3OH9A 1M3HA 3N0UA 1PU7A 1LWVA 2JHNA 4EJYA 4EVVA 2NOZA 5AN4A 4B21A 4OFEA 1RRQA 2NOFA 4DK9A 1LMZA 1M3QA 1P7MA 1KG5A 2JG6A 3KTUA 4UNFA 3CWUA 4EW4A 4AIAA 4EW0A 4PIIA 4AI5A 1MUYA 1N39A 4E9HA 1PVSA 5KN8A 4YPHA 4AI4A 3OGDA 3CW7A 2XHIA 4YPRA 3OH6A 1XG7A 2NOBA 2OFKA 3IHOA 1XQOA 3CWSA 1KG6A 2H56A 4HSBA 5DPKA 4E9GA 2NOIA 4E9FA 2YG9A 3F10A 1WEIA 2NOLA 1LWYA 1ORNA 3I0WA 2YG8A 1KG3A 1NGNA 4YOQA 1EBMA 3FHGA 3I0XA 2I5WA 1MUDA 1KO9A 1LWWA 3G0QA 1KEAA 3CWTA 1KG7A 1KG4A 4B23A 4EA4A 4E9EA 3D4VA 3FSPA 1KQJA 4B22A 1YQRA 1YQMA 1P59A 3KNTA 3F0ZA 1DIZA 1KG2A 2NOEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YQK A;  1ORP A;  1N3C A;  2ABK A;  4EJZ A;  1XQP A;  3CVS A;  1PU8 A;  3IH7 A;  1FN7 A;  1MPG A;  1PU6 A;  1WEF A;  1HU0 A;  2JHJ A;  4UOB A;  1WEG A;  4EA5 A;  1NKU A;  3S6I A;  4OFH A;  1YQL A;  1N3A A;  3CVT A;  1VRL A;  2OFI A;  1MUN A;  3FHF A;  5KN9 A;  4B24 A;  5CHZ A;  3CWA A;  4OFA A;  2NOH A;  3N5N X;  1RRS A;  3OH9 A;  1M3H A;  3N0U A;  1PU7 A;  1LWV A;  2JHN A;  4EJY A;  4EVV A;  2NOZ A;  5AN4 A;  4B21 A;  4OFE A;  1RRQ A;  2NOF A;  4DK9 A;  1LMZ A;  1M3Q A;  1P7M A;  1KG5 A;  2JG6 A;  3KTU A;  4UNF A;  3CWU A;  4EW4 A;  4AIA A;  4EW0 A;  4PII A;  4AI5 A;  1MUY A;  1N39 A;  4E9H A;  1PVS A;  5KN8 A;  4YPH A;  4AI4 A;  3OGD A;  3CW7 A;  2XHI A;  4YPR A;  3OH6 A;  1XG7 A;  2NOB A;  2OFK A;  3IHO A;  1XQO A;  3CWS A;  1KG6 A;  2H56 A;  4HSB A;  5DPK A;  4E9G A;  2NOI A;  4E9F A;  2YG9 A;  3F10 A;  1WEI A;  2NOL A;  1LWY A;  1ORN A;  3I0W A;  2YG8 A;  1KG3 A;  1NGN A;  4YOQ A;  1EBM A;  3FHG A;  3I0X A;  2I5W A;  1MUD A;  1KO9 A;  1LWW A;  3G0Q A;  1KEA A;  3CWT A;  1KG7 A;  1KG4 A;  4B23 A;  4EA4 A;  4E9E A;  3D4V A;  3FSP A;  1KQJ A;  4B22 A;  1YQR A;  1YQM A;  1P59 A;  3KNT A;  3F0Z A;  1DIZ A;  1KG2 A;  2NOE A; 
#chains in the Genus database with same CATH topology
 2D0C A;  3NNQ A;  1N3C A;  3TE5 A;  3IH7 A;  1FN7 A;  1EUV A;  3OYD A;  2JHJ A;  4ROD B;  4UOB A;  4EA5 A;  1NKU A;  1YQL A;  3OYK A;  1N3A A;  2Z8U A;  3OYA A;  1MUN A;  1PCM X;  2NOH A;  3N5N X;  2Z0F A;  3OH9 A;  1M3H A;  3N0U A;  2NOZ A;  2Y8L A;  1VTO A;  1B9K A;  3OSE A;  3OLP A;  1LMZ A;  5IYB P;  4ROC B;  2JOI A;  1KG5 A;  2JG6 A;  3KTU A;  1JDY A;  2H4L X;  4Q11 A;  2QRC A;  3OS0 A;  1MUY A;  3OS2 A;  2HKP A;  2F7L A;  2XHI A;  4YPR A;  3L2V A;  2HZM A;  3IHO A;  5F9C A;  4HSB A;  3ENO C;  3I3W A;  1M5Q 1;  1K35 A;  4BAC A;  1PZD A;  4PY5 A;  1TBA B;  3VN5 A;  4IL8 A;  3FHG A;  5BMP A;  2I5W A;  1QNB A;  1LWW A;  2IV8 A;  3LCN A;  2OOX A;  2Y8Q A;  3FSP A;  4ZTF A;  1YQM A;  3F0Z A;  1DIZ A;  3N89 A;  1YTB A;  4BDY A;  2NOE A;  3KRM A;  1YQK A;  1ORP A;  1XQP A;  3CVS A;  2HL9 A;  4EAK A;  1PU6 A;  1QN8 A;  3D7Q A;  2YA3 A;  3NA5 A;  1QN9 A;  3PMG A;  3C04 A;  5KN9 A;  4OFA A;  3CWA A;  4EAI A;  1K2Y X;  3ASM A;  3RPJ A;  1C47 A;  4EVV A;  3SNS A;  1RM1 A;  1AIS A;  1C9B B;  2NOF A;  4DK9 A;  1M3Q A;  2V8Q A;  5EPC A;  3EAY A;  1NVP A;  2FKM X;  1TUO A;  3OYI A;  3OYE A;  1W80 A;  4B0A A;  5FRM A;  4EW0 A;  4AI5 A;  1NGM A;  4E7L A;  1N39 A;  1WQA A;  3S3O A;  4E7J A;  4E7H A;  3CW7 A;  1T6A A;  1QNE A;  4EAL A;  4BDZ A;  1XQO A;  3CWS A;  1XSZ A;  1KYD A;  4E9F A;  2YG9 A;  3F10 A;  3DPU A;  1LWY A;  3OST A;  3PDK A;  3L2Q A;  1QN6 A;  1QN5 A;  2FUV A;  1KG3 A;  4ROE B;  1NGN A;  4YOQ A;  1EBM A;  4D7R A;  1VTL E;  1MUD A;  4BE0 A;  1P5G X;  1KO9 A;  3G0Q A;  3OYH A;  4E9E A;  1VKL A;  4B22 A;  1PCZ A;  4E7I A;  2DKD A;  4I8O A;  3L2U A;  2IV9 A;  1CDW A;  2O3O A;  4EJZ A;  1E42 A;  1PCJ X;  1WJW A;  5JN5 A;  1WEF A;  1WEG A;  2D0B A;  2D0A A;  1KY6 A;  3S6I A;  5FRO A;  4NZG A;  2PWW A;  3FHF A;  2JPS A;  5CHZ A;  4IKF A;  1JFI C;  2W03 A;  2JHN A;  1VOK A;  4BJU A;  2ZFD B;  5AN4 A;  4B21 A;  1RRQ A;  3OYJ A;  4WX8 A;  1QTS A;  4UNF A;  4EW4 A;  2HZS A;  1NH2 A;  1KY7 A;  2R5X A;  1PVS A;  4BE1 A;  3HS8 A;  5KN8 A;  3OYN A;  4AI4 A;  2JPI A;  3R2X C;  3OGD A;  1VOL B;  3OH6 A;  2NOB A;  3S3M A;  1C4G A;  2VJ0 A;  2OFK A;  1D3U A;  1KG6 A;  1TBP A;  3OY9 A;  2H56 A;  2FGT A;  2MJ7 A;  2NOI A;  3BKQ X;  3HS9 A;  1WEI A;  3EIK A;  3TDH A;  2V9J A;  3OYC A;  2NOL A;  3OYF A;  2MZ8 A;  1ORN A;  3I0W A;  1QNA A;  1KYF A;  4C7P A;  2V92 A;  1QNC A;  2QRE A;  1KEA A;  1KG7 A;  4B23 A;  1UT4 A;  4EA4 A;  5IYD P;  1MP9 A;  3D4V A;  1QTP A;  5BMN A;  3UW2 A;  1YQR A;  1P59 A;  4EAJ A;  4TPS A;  2QLV A;  3DPT A;  1KG2 A;  1UL7 A;  2ABK A;  1PU8 A;  3ULX A;  2NVM A;  2NWV A;  1MPG A;  1HU0 A;  2W04 A;  3T4N A;  3OS1 A;  4HJH A;  3VW4 A;  1UT7 A;  4OFH A;  4BE2 A;  3CVT A;  1VRL A;  2OFI A;  2YH5 A;  1KYU A;  5HSH A;  2QRD A;  3OYL A;  4B24 A;  4QG5 A;  2DKC A;  5KL0 A;  1RRS A;  4WZS D;  1J3M A;  1QN4 A;  1PU7 A;  1LWV A;  1LXT A;  3H1Z A;  4EJY A;  4DUL A;  2EHB D;  1QN3 A;  2QR1 A;  3OSM A;  4OFE A;  2OOY A;  3OYB A;  1YTF A;  1U84 A;  4EAG A;  1P7M A;  2H5A X;  3CWU A;  4D7Q A;  1TGH A;  4AIA A;  3OC3 C;  4PII A;  1V5S A;  4E9H A;  1Q9U A;  2NLV A;  1P5D X;  4YPH A;  2V75 A;  1XG7 A;  5FRN A;  1QN7 A;  5IYC P;  3L2R A;  4CFF A;  5DPK A;  5JMV D;  4E9G A;  2HL8 A;  1KFI A;  3L2W A;  1KFQ A;  3RSM A;  4E7K A;  2YG8 A;  2DKA A;  2LAE A;  4ZTJ A;  3I0X A;  3OYM A;  1R4X A;  3OCI A;  3CWT A;  1KG4 A;  2G30 A;  1KQJ A;  3S3N A;  3KNT A;  2FKF A;  3ENC A;  3OYG A;  4WXA A;  4MRQ A; 
#chains in the Genus database with same CATH homology
 1YQK A;  1ORP A;  1N3C A;  2ABK A;  4EJZ A;  1XQP A;  3CVS A;  1PU8 A;  3IH7 A;  1FN7 A;  1MPG A;  1PU6 A;  1WEF A;  1HU0 A;  2JHJ A;  4UOB A;  1WEG A;  4EA5 A;  1NKU A;  3S6I A;  4OFH A;  1YQL A;  1N3A A;  3CVT A;  1VRL A;  2OFI A;  1MUN A;  3FHF A;  5KN9 A;  4B24 A;  5CHZ A;  3CWA A;  4OFA A;  2NOH A;  3N5N X;  1RRS A;  3OH9 A;  1M3H A;  3N0U A;  1PU7 A;  1LWV A;  2JHN A;  4EJY A;  4EVV A;  2NOZ A;  5AN4 A;  4B21 A;  4OFE A;  1RRQ A;  2NOF A;  4DK9 A;  1LMZ A;  1M3Q A;  1P7M A;  1KG5 A;  2JG6 A;  3KTU A;  4UNF A;  3CWU A;  4EW4 A;  4AIA A;  4EW0 A;  4PII A;  4AI5 A;  1MUY A;  1N39 A;  4E9H A;  1PVS A;  5KN8 A;  4YPH A;  4AI4 A;  3OGD A;  3CW7 A;  2XHI A;  4YPR A;  3OH6 A;  1XG7 A;  2NOB A;  2OFK A;  3IHO A;  1XQO A;  3CWS A;  1KG6 A;  2H56 A;  4HSB A;  5DPK A;  4E9G A;  2NOI A;  4E9F A;  2YG9 A;  3F10 A;  1WEI A;  2NOL A;  1LWY A;  1ORN A;  3I0W A;  2YG8 A;  1KG3 A;  1NGN A;  4YOQ A;  1EBM A;  3FHG A;  3I0X A;  2I5W A;  1MUD A;  1KO9 A;  1LWW A;  3G0Q A;  1KEA A;  3CWT A;  1KG7 A;  1KG4 A;  4B23 A;  4EA4 A;  4E9E A;  3D4V A;  3FSP A;  1KQJ A;  4B22 A;  1YQR A;  1YQM A;  1P59 A;  3KNT A;  3F0Z A;  1DIZ A;  1KG2 A;  2NOE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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