2JTOA

Solution structure of tick carboxypeptidase inhibitor
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
75
structure length
75
Chain Sequence
NECVSKGFGCLPQSDCPQEARLSYGGCSTVCCDLSKLTGCKGKGGECNPLDRQCKELQAESASCGKGQKCCVWLH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The NMR structure and dynamics of the two-domain tick carboxypeptidase inhibitor reveal flexibility in its free form and stiffness upon binding to human carboxypeptidase B.
pubmed doi rcsb
molecule tags Hydrolase inhibitor
source organism Rhipicephalus bursa
molecule keywords Carboxypeptidase inhibitor
total genus 9
structure length 75
sequence length 75
ec nomenclature
pdb deposition date 2007-08-03
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.20.10 Mainly Beta Single Sheet Anthopleurin-A Anthopleurin-A 2jtoA02
2.20.20.50 Mainly Beta Single Sheet Anthopleurin-A Anthopleurin-A 2jtoA01
1ZUEA 1BDSA 3D4UB 1Z99A 3LMSB 4GV5A 1ATXA 2RNGA 1ZUFA 2H9XA 2K2XA 1ZLIB 1B8WA 1H5OA 1SH1A 2MN3A 1D6BA 1WXNA 2JTOA 1AHLA 1SHIA 1APFA 2MUBA 1ZLHB 1WQKA 2BDSA 2SH1A
chains in the Genus database with same CATH superfamily
1ZUEA 1BDSA 2JR3A 3D4UB 1Z99A 3LMSB 4GV5A 1ATXA 1ZHHB 2RNGA 1EL6A 1ZUFA 3C38A 3KEZA 2IKEA 2H9XA 4YIRA 2QSHA 2DLAA 2QSFA 3MYVA 2QSGA 1ZLIB 2K2XA 2IKDA 2HJ9C 1B8WA 1H5OA 1SH1A 2MN3A 1D6BA 1WXNA 1GKUB 2JTOA 1GL9B 1AHLA 1SHIA 3C30A 3MCXA 2HJEA 1APFA 2MUBA 2B9KA 1ZLHB 2XXLA 1WQKA 2BDSA 2SH1A 3IF4A
chains in the Genus database with same CATH topology
1ZUEA 1BDSA 2JR3A 3D4UB 1Z99A 3LMSB 4GV5A 1ATXA 1ZHHB 2RNGA 1ZUFA 3C38A 3KEZA 2IKEA 2H9XA 4YIRA 2QSHA 2DLAA 2QSFA 3MYVA 2QSGA 1ZLIB 2K2XA 2IKDA 2HJ9C 1B8WA 1H5OA 1SH1A 2MN3A 1D6BA 1WXNA 2JTOA 1AHLA 1SHIA 3C30A 3MCXA 2HJEA 1APFA 2MUBA 2B9KA 1ZLHB 2XXLA 1WQKA 2BDSA 2SH1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZUE A;  1BDS A;  3D4U B;  1Z99 A;  3LMS B;  4GV5 A;  1ATX A;  2RNG A;  1ZUF A;  2H9X A;  2K2X A;  1ZLI B;  1B8W A;  1H5O A;  1SH1 A;  2MN3 A;  1D6B A;  1WXN A;  2JTO A;  1AHL A;  1SHI A;  1APF A;  2MUB A;  1ZLH B;  1WQK A;  2BDS A;  2SH1 A; 
#chains in the Genus database with same CATH topology
 1ZUE A;  1BDS A;  2JR3 A;  3D4U B;  1Z99 A;  3LMS B;  4GV5 A;  1ATX A;  1ZHH B;  2RNG A;  1EL6 A;  1ZUF A;  3C38 A;  3KEZ A;  2IKE A;  2H9X A;  4YIR A;  2QSH A;  2DLA A;  2QSF A;  3MYV A;  2QSG A;  1ZLI B;  2K2X A;  2IKD A;  2HJ9 C;  1B8W A;  1H5O A;  1SH1 A;  2MN3 A;  1D6B A;  1WXN A;  1GKU B;  2JTO A;  1GL9 B;  1AHL A;  1SHI A;  3C30 A;  3MCX A;  2HJE A;  1APF A;  2MUB A;  2B9K A;  1ZLH B;  2XXL A;  1WQK A;  2BDS A;  2SH1 A;  3IF4 A; 
#chains in the Genus database with same CATH homology
 1ZUE A;  1BDS A;  2JR3 A;  3D4U B;  1Z99 A;  3LMS B;  4GV5 A;  1ATX A;  1ZHH B;  2RNG A;  1ZUF A;  3C38 A;  3KEZ A;  2IKE A;  2H9X A;  4YIR A;  2QSH A;  2DLA A;  2QSF A;  3MYV A;  2QSG A;  1ZLI B;  2K2X A;  2IKD A;  2HJ9 C;  1B8W A;  1H5O A;  1SH1 A;  2MN3 A;  1D6B A;  1WXN A;  2JTO A;  1AHL A;  1SHI A;  3C30 A;  3MCX A;  2HJE A;  1APF A;  2MUB A;  2B9K A;  1ZLH B;  2XXL A;  1WQK A;  2BDS A;  2SH1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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