2K3SA

Haddock-derived structure of the ch-domain of the smoothelin-like 1 complexed with the c-domain of apocalmodulin
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
119
structure length
119
Chain Sequence
GPLGSKNMLLEWCRAMTRNYEHVDIQNFSSSWSSGMAFCALIHKFFPEAFDYAELDPAKRRHNFTLAFSTAEKLADCAQLLEVDDMVRLAVPDSKCVYTYIQELYRSLVQKGLVKTKKK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of the calponin homology (CH) domain from the smoothelin-like 1 protein: a unique apocalmodulin-binding mode and the possible role of the C-terminal type-2 CH-domain in smooth muscle relaxation.
pubmed doi rcsb
molecule tags Protein binding
source organism Mus musculus
molecule keywords Smoothelin-like protein 1
total genus 39
structure length 119
sequence length 119
ec nomenclature
pdb deposition date 2008-05-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.418.10 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Calponin-like domain 2k3sA01
2QJZA 5J8EA 1BKRA 1QAGA 5A38A 2D88A 3HOPA 2EYNA 1TJTA 1BHDA 4Q59A 1P5SA 1WIXA 2K3SA 3REPB 2JV9A 1WKUA 5A36A 1RT8A 2VZGB 3KMUB 1WYLA 1AA2A 1PXYA 2VZIB 5A37A 1V5KA 2DK9A 2QJXA 4Q57B 4B7LA 3JAKM 2D86A 2K2RA 3KMWB 2WFNA 1VKAA 3HOCA 4Q58A 2VZCA 3JARM 1MB8A 4TXKA 1WYPA 1UJOA 1PA7A 1H67A 2WA6A 2VZDA 1SH5A 1WYOA 1WYRA 1WYNA 2RR8A 5BVRA 3F7PA 1WYMA 2WA5A 2D85A 2D89A 3I6XA 4EDNA 2D87A 3CO1A 1AOAA 3FERA 5A4BA 3KY9A 1UEGA 1DXXA 1P2XA 2R8UA 4EDMA 5L0OA 2EE7A 2L3GA 4TXIA 1SH6A 2R0OA 3JALM 3HORA 2E9KA 2WA7A 2EYIA 4EDLA 1WJOA 2YRNA 1WYQA
chains in the Genus database with same CATH superfamily
2QJZA 1EUVA 5J8EA 1BKRA 4LVRA 1QAGA 2HL9A 5A38A 3VP7A 2D88A 3HOPA 2EYNA 1TJTA 1BHDA 4Q59A 1P5SA 1WIXA 2K3SA 3REPB 2JV9A 1WKUA 5A36A 2VE7C 1RT8A 2VZGB 2IGPA 3KMUB 1WYLA 1AA2A 1PXYA 2VZIB 5A37A 1V5KA 2DK9A 2QJXA 4Q57B 4B7LA 3JAKM 2D86A 2K2RA 3KMWB 2WFNA 4LVPA 1VKAA 4DDPA 3HOCA 4Q58A 2VZCA 3JARM 1MB8A 4TXKA 1WYPA 1UJOA 2WE6A 1PA7A 1H67A 5FMUA 2WA6A 2VZDA 5FMTA 2HKPA 1SH5A 1WYOA 1WYRA 1WYNA 2RR8A 2WDTA 5BVRA 3F7PA 1WYMA 2WA5A 2D85A 2D89A 3I6XA 4EDNA 3EAYA 2D87A 3CO1A 1AOAA 3FERA 5A4BA 3KY9A 1UEGA 1DXXA 1P2XA 2R8UA 2EQOA 2HL8A 4EDMA 5L0OA 2EE7A 2L3GA 4TXIA 1SH6A 2R0OA 3JALM 3HORA 2E9KA 2WA7A 2EYIA 4EDLA 2VE7A 1WJOA 2YRNA 1WYQA
chains in the Genus database with same CATH topology
2QJZA 5J8EA 1BKRA 1QAGA 5A38A 2D88A 3HOPA 2EYNA 1TJTA 1BHDA 4Q59A 1P5SA 1WIXA 2K3SA 3REPB 2JV9A 1WKUA 5A36A 1RT8A 2VZGB 3KMUB 1WYLA 1AA2A 1PXYA 2VZIB 5A37A 1V5KA 2DK9A 2QJXA 4Q57B 4B7LA 3JAKM 2D86A 2K2RA 3KMWB 2WFNA 1VKAA 3HOCA 4Q58A 2VZCA 3JARM 1MB8A 4TXKA 1WYPA 1UJOA 1PA7A 1H67A 2WA6A 2VZDA 1SH5A 1WYOA 1WYRA 1WYNA 2RR8A 5BVRA 3F7PA 1WYMA 2WA5A 2D85A 2D89A 3I6XA 4EDNA 2D87A 3CO1A 1AOAA 3FERA 5A4BA 3KY9A 1UEGA 1DXXA 1P2XA 2R8UA 4EDMA 5L0OA 2EE7A 2L3GA 4TXIA 1SH6A 2R0OA 3JALM 3HORA 2E9KA 2WA7A 2EYIA 4EDLA 1WJOA 2YRNA 1WYQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QJZ A;  5J8E A;  1BKR A;  1QAG A;  5A38 A;  2D88 A;  3HOP A;  2EYN A;  1TJT A;  1BHD A;  4Q59 A;  1P5S A;  1WIX A;  2K3S A;  3REP B;  2JV9 A;  1WKU A;  5A36 A;  1RT8 A;  2VZG B;  3KMU B;  1WYL A;  1AA2 A;  1PXY A;  2VZI B;  5A37 A;  1V5K A;  2DK9 A;  2QJX A;  4Q57 B;  4B7L A;  3JAK M;  2D86 A;  2K2R A;  3KMW B;  2WFN A;  1VKA A;  3HOC A;  4Q58 A;  2VZC A;  3JAR M;  1MB8 A;  4TXK A;  1WYP A;  1UJO A;  1PA7 A;  1H67 A;  2WA6 A;  2VZD A;  1SH5 A;  1WYO A;  1WYR A;  1WYN A;  2RR8 A;  5BVR A;  3F7P A;  1WYM A;  2WA5 A;  2D85 A;  2D89 A;  3I6X A;  4EDN A;  2D87 A;  3CO1 A;  1AOA A;  3FER A;  5A4B A;  3KY9 A;  1UEG A;  1DXX A;  1P2X A;  2R8U A;  4EDM A;  5L0O A;  2EE7 A;  2L3G A;  4TXI A;  1SH6 A;  2R0O A;  3JAL M;  3HOR A;  2E9K A;  2WA7 A;  2EYI A;  4EDL A;  1WJO A;  2YRN A;  1WYQ A; 
#chains in the Genus database with same CATH topology
 2QJZ A;  1EUV A;  5J8E A;  1BKR A;  4LVR A;  1QAG A;  2HL9 A;  5A38 A;  3VP7 A;  2D88 A;  3HOP A;  2EYN A;  1TJT A;  1BHD A;  4Q59 A;  1P5S A;  1WIX A;  2K3S A;  3REP B;  2JV9 A;  1WKU A;  5A36 A;  2VE7 C;  1RT8 A;  2VZG B;  2IGP A;  3KMU B;  1WYL A;  1AA2 A;  1PXY A;  2VZI B;  5A37 A;  1V5K A;  2DK9 A;  2QJX A;  4Q57 B;  4B7L A;  3JAK M;  2D86 A;  2K2R A;  3KMW B;  2WFN A;  4LVP A;  1VKA A;  4DDP A;  3HOC A;  4Q58 A;  2VZC A;  3JAR M;  1MB8 A;  4TXK A;  1WYP A;  1UJO A;  2WE6 A;  1PA7 A;  1H67 A;  5FMU A;  2WA6 A;  2VZD A;  5FMT A;  2HKP A;  1SH5 A;  1WYO A;  1WYR A;  1WYN A;  2RR8 A;  2WDT A;  5BVR A;  3F7P A;  1WYM A;  2WA5 A;  2D85 A;  2D89 A;  3I6X A;  4EDN A;  3EAY A;  2D87 A;  3CO1 A;  1AOA A;  3FER A;  5A4B A;  3KY9 A;  1UEG A;  1DXX A;  1P2X A;  2R8U A;  2EQO A;  2HL8 A;  4EDM A;  5L0O A;  2EE7 A;  2L3G A;  4TXI A;  1SH6 A;  2R0O A;  3JAL M;  3HOR A;  2E9K A;  2WA7 A;  2EYI A;  4EDL A;  2VE7 A;  1WJO A;  2YRN A;  1WYQ A; 
#chains in the Genus database with same CATH homology
 2QJZ A;  5J8E A;  1BKR A;  1QAG A;  5A38 A;  2D88 A;  3HOP A;  2EYN A;  1TJT A;  1BHD A;  4Q59 A;  1P5S A;  1WIX A;  2K3S A;  3REP B;  2JV9 A;  1WKU A;  5A36 A;  1RT8 A;  2VZG B;  3KMU B;  1WYL A;  1AA2 A;  1PXY A;  2VZI B;  5A37 A;  1V5K A;  2DK9 A;  2QJX A;  4Q57 B;  4B7L A;  3JAK M;  2D86 A;  2K2R A;  3KMW B;  2WFN A;  1VKA A;  3HOC A;  4Q58 A;  2VZC A;  3JAR M;  1MB8 A;  4TXK A;  1WYP A;  1UJO A;  1PA7 A;  1H67 A;  2WA6 A;  2VZD A;  1SH5 A;  1WYO A;  1WYR A;  1WYN A;  2RR8 A;  5BVR A;  3F7P A;  1WYM A;  2WA5 A;  2D85 A;  2D89 A;  3I6X A;  4EDN A;  2D87 A;  3CO1 A;  1AOA A;  3FER A;  5A4B A;  3KY9 A;  1UEG A;  1DXX A;  1P2X A;  2R8U A;  4EDM A;  5L0O A;  2EE7 A;  2L3G A;  4TXI A;  1SH6 A;  2R0O A;  3JAL M;  3HOR A;  2E9K A;  2WA7 A;  2EYI A;  4EDL A;  1WJO A;  2YRN A;  1WYQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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