2K4TA

Solution structure of human vdac-1 in ldao micelles
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
285
structure length
285
Chain Sequence
b'MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVTGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKREHINLGCDMDFDIAGPSIRGALVLGYEGWLAGYQMNFETAKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQIDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQALE'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Voltage-dependent anion-selective channel protein 1
publication title Solution structure of the integral human membrane protein VDAC-1 in detergent micelles.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Membrane protein,apoptosis
total genus 43
structure length 285
sequence length 285
ec nomenclature
pdb deposition date 2008-06-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01459 Porin_3 Eukaryotic porin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.160.10 Mainly Beta Beta Barrel Porin Porin 2k4tA00
4LSFA 4FOZA 3T0SA 4C69X 5DL7A 2ODJA 3PORA 2Y2XA 3UPGA 2XE3A 1HXUA 1GFOA 3SYBA 4JFBA 4BUMX 3A2SX 1HXTA 4LSIA 3HW9A 3FYXA 2O4VA 2PRNA 3POUA 1E54A 4KRAA 1OPFA 3POQA 3SY7A 4LSHA 5PRNA 3WI5A 3WI4A 4FT6A 1BH3A 4D65A 7PRNA 2FGQX 3K19A 3VZUX 3JTYA 3VY9X 2FGRA 1BT9A 5DL8A 1HXXA 2QTKA 3VY8X 3HWBA 4D64A 2J4UP 2XE5A 1H6S1 4RJWA 2PORA 3O0EA 3T24A 5DL5A 3UU2A 1PRNA 2Y0LA 1GFQA 2Y0HA 4FSOA 3POXA 4KR8A 2Y0KA 4FRTA 4GCPA 3SY9A 3T20A 2XE1A 4KR4A 5JDPA 4FRXA 1GFNA 2K4TA 2J1NA 4GCQA 4FSPA 3PRNA 4AUIA 2XE2A 3EMNX 8PRNA 1GFPA 4GCSA 1GFMA 2ZFGA 4RJXA 6PRNA 1OSMA 3VZWX 1MPFA 2XG6A 4LSEA 3SYSA 2OMFA 3SZVA 3NSGA 3VZTX 1PHOA 5DL6A 2ZLDA 4D5UA 3SZDA 4FMSA 5FVNA
chains in the Genus database with same CATH superfamily
4RL9A 5IYUA 4LSFA 3AAAB 3UAQA 2R4PA 4FOZA 4K3BA 4O4UA 1QJ8A 2ODJA 3PORA 1ZHWA 2Y2XA 1P4TA 4FZMA 5DL7A 1THQA 5KAFO 5ADXK 2M06A 3AA0B 3DWNA 4C4VB 2XE3A 3UPGA 1HXUA 1GFOA 3SYBA 2AXTO 3AA6A 1S5LO 2W81C 5G38A 2YNKA 2XTQA 4RLCA 1QJ9A 5GV0A 2M07A 4JFBA 4BUMX 3A2SX 1HXTA 5B66O 1QJPA 4K3CA 3HW9A 4LSIA 4FQEA 4N75A 3FYXA 3KZIO 3AAEB 1T1LA 2KXPA 3T0SA 2O4VA 2N2MA 2PRNA 4N59A 4AYID 5H2FO 3POUA 1T16A 4IL6O 1E54A 4PJ0O 3V8UA 4AYNA 4JCHA 4KRAA 4E1SA 1G90A 1ORMA 2F1TA 3AA7A 2IWVA 2KC0A 3LK3B 3JCUO 3PGSA 1OPFA 4G75A 5E79O 2KZ7B 2ERVA 3TZGA 4Z3TA 5T5FA 1Q9GA 3POQA 5GTIO 3SY7A 4GF4A 2F1CX 4LSHA 4O3XB 5PRNA 3VE1A 3WI5A 1MM5A 3BRZA 4FT6A 3DWOX 2R4NA 3DA3A 4N74A 3GP6A 3LK2B 1BH3A 4O3ZA 3QRAA 1MM4A 4D65A 2FGQX 4GHBA 3VE2A 5AFUL 2X27X 7PRNA 2JMMA 2XMXA 3K19A 3VZUX 3AAAA 3KVDD 4AFKA 4U9CA 2R4LA 3DA4A 3PF1A 4PR7A 2R88A 3JTYA 3VY9X 3AA0A 3HOLA 4FUVA 4C4VA 5TISO 4XNLA 1BT9A 2FGRA 5DL8A 3WU2O 1ZHXA 1HXXA 2JQYA 2QTKA 3AAEA 3VY8X 3HWBA 4D64A 2J4UP 2XE5A 5B5EO 1H6S1 1IZNB 4RJWA 3RBHA 5D5DA 4AKRB 2PORA 3O0EA 4UB8O 2IWWA 2MHLA 4FESA 1ZHYA 3T24A 2KDYA 4G76A 3LK3A 5DL5A 4PUXA 2KZ7A 3HOEA 5EE2A 4N58A 3UU2A 1PRNA 3AA1B 4F4BA 2Y0LA 1GFQA 3DZMA 3PQUA 1ZHTA 2F1VA 5G39A 3LK2A 4O49A 2Y0HA 4FSOA 2WJRA 3POXA 4KR8A 4O4XA 4AYDC 2Y0KA 3BS0A 4CTDA 4FRTA 1Q9FA 5KAIO 4GCPA 3SY9A 2XTRA 2XE1A 4KR4A 3T20A 2R89A 5AFUK 2Y7SA 3A0HO 2GE4A 5JDPA 3PQSA 4FRXA 5ADXL 4AKMA 4O3WA 2R8AA 4AYEC 2WJQA 3C5OA 4UB6O 1GFNA 2J1NA 2K4TA 4FSPA 4GCQA 4AYMC 3PRNA 5G26A 3LK42 3BRYA 2LHFA 3AA6B 3WI4A 2R4OA 4XNKA 4AUIA 2XE2A 2W80C 1BXWA 3EMNX 3PGUA 8PRNA 1GFPA 2LFUA 4GCSA 4RLBA 1GFMA 2ZFGA 2K0LA 4QQ1A 1IZNA 4AKRA 4RJXA 4E1TA 4C69X 2KXPB 4B61A 6PRNA 5GTHO 4FZNA 4FZLA 1OSMA 3VZWX 1MPFA 1ZHZA 2XG6A 3AA1A 3AA7B 4LSEA 5G3AA 3SYSA 3NJTA 2OMFA 2X9KA 2YPVA 3QRCA 4O3YA 2MNHA 3SZVA 4AZLA 3NSGA 3VZTX 1PHOA 5DL6A 2ZLDA 4C00A 1YS5A 3SZDA 2WVPA 4FMSA 5FVNA 4D5UA 3LK41 3PGRA 3A0BO 2N2LA 3G7GA
chains in the Genus database with same CATH topology
4RL9A 5IYUA 4LSFA 3AAAB 3UAQA 4FOZA 3T0SA 4O4UA 5DL7A 1QJ8A 2ODJA 3PORA 1ZHWA 2Y2XA 1P4TA 4FZMA 4AYNA 1THQA 5ADXK 2M06A 3AA0B 3UPGA 2XE3A 1HXUA 1GFOA 3SYBA 3AA6A 2W81C 2YNKA 2XTQA 4RLCA 1QJ9A 5GV0A 2M07A 4JFBA 4BUMX 3A2SX 1HXTA 1QJPA 4LSIA 3HW9A 3FYXA 3AAEB 2KXPA 2O4VA 2N2MA 2PRNA 4N59A 4AYID 3POUA 1G90A 4E1SA 1E54A 3V8UA 4JCHA 4KRAA 1ORMA 2F1TA 3AA7A 4AKMA 2KC0A 3LK3B 4C69X 1OPFA 4G75A 3TZGA 2KZ7B 2ERVA 4Z3TA 5T5FA 1Q9GA 3POQA 3SY7A 4GF4A 4LSHA 4O3XB 5PRNA 3VE1A 3WI5A 3WI4A 1MM5A 4FT6A 3DA3A 3GP6A 3LK2B 1BH3A 4O3ZA 3QRAA 1MM4A 4D65A 2FGQX 4GHBA 3VE2A 5AFUL 2X27X 7PRNA 2JMMA 2XMXA 3K19A 3VZUX 3AAAA 3KVDD 4AFKA 4U9CA 3DA4A 3JTYA 3VY9X 3AA0A 3HOLA 4FUVA 4XNLA 1BT9A 2FGRA 5DL8A 1ZHXA 1HXXA 2QTKA 3AAEA 3VY8X 3HWBA 4D64A 2J4UP 2XE5A 1H6S1 1IZNB 4RJWA 3RBHA 5D5DA 4AKRB 2PORA 3O0EA 2MHLA 4FESA 1ZHYA 3T24A 2KDYA 4G76A 3LK3A 5DL5A 4PUXA 2KZ7A 3HOEA 5EE2A 4N58A 3UU2A 1PRNA 3AA1B 4F4BA 2Y0LA 1GFQA 3PQUA 1ZHTA 2F1VA 3LK2A 4O49A 2Y0HA 4FSOA 3POXA 4KR8A 4O4XA 4AYDC 4B61A 2Y0KA 4FRTA 1Q9FA 4GCPA 3SY9A 2XTRA 2XE1A 4KR4A 3T20A 5AFUK 2Y7SA 2GE4A 5JDPA 3PQSA 4FRXA 5ADXL 4O3WA 4AYEC 3C5OA 1GFNA 2J1NA 2K4TA 4FSPA 4GCQA 4AYMC 3PRNA 5G26A 3LK42 2LHFA 3AA6B 4AUIA 4XNKA 2XE2A 2W80C 1BXWA 3EMNX 8PRNA 1GFPA 2LFUA 4GCSA 4RLBA 1GFMA 2ZFGA 2K0LA 4QQ1A 1IZNA 4AKRA 4RJXA 4E1TA 2KXPB 6PRNA 4FZNA 4FZLA 1OSMA 3VZWX 1MPFA 1ZHZA 2XG6A 3AA1A 3AA7B 4LSEA 3SYSA 2OMFA 2YPVA 3QRCA 4O3YA 2MNHA 3SZVA 4AZLA 3NSGA 3VZTX 1PHOA 5DL6A 2ZLDA 1YS5A 3SZDA 4FMSA 5FVNA 4D5UA 3LK41 2N2LA 3G7GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LSF A;  4FOZ A;  3T0S A;  4C69 X;  5DL7 A;  2ODJ A;  3POR A;  2Y2X A;  3UPG A;  2XE3 A;  1HXU A;  1GFO A;  3SYB A;  4JFB A;  4BUM X;  3A2S X;  1HXT A;  4LSI A;  3HW9 A;  3FYX A;  2O4V A;  2PRN A;  3POU A;  1E54 A;  4KRA A;  1OPF A;  3POQ A;  3SY7 A;  4LSH A;  5PRN A;  3WI5 A;  3WI4 A;  4FT6 A;  1BH3 A;  4D65 A;  7PRN A;  2FGQ X;  3K19 A;  3VZU X;  3JTY A;  3VY9 X;  2FGR A;  1BT9 A;  5DL8 A;  1HXX A;  2QTK A;  3VY8 X;  3HWB A;  4D64 A;  2J4U P;  2XE5 A;  1H6S 1;  4RJW A;  2POR A;  3O0E A;  3T24 A;  5DL5 A;  3UU2 A;  1PRN A;  2Y0L A;  1GFQ A;  2Y0H A;  4FSO A;  3POX A;  4KR8 A;  2Y0K A;  4FRT A;  4GCP A;  3SY9 A;  3T20 A;  2XE1 A;  4KR4 A;  5JDP A;  4FRX A;  1GFN A;  2K4T A;  2J1N A;  4GCQ A;  4FSP A;  3PRN A;  4AUI A;  2XE2 A;  3EMN X;  8PRN A;  1GFP A;  4GCS A;  1GFM A;  2ZFG A;  4RJX A;  6PRN A;  1OSM A;  3VZW X;  1MPF A;  2XG6 A;  4LSE A;  3SYS A;  2OMF A;  3SZV A;  3NSG A;  3VZT X;  1PHO A;  5DL6 A;  2ZLD A;  4D5U A;  3SZD A;  4FMS A;  5FVN A; 
#chains in the Genus database with same CATH topology
 4RL9 A;  5IYU A;  4LSF A;  3AAA B;  3UAQ A;  2R4P A;  4FOZ A;  4K3B A;  4O4U A;  1QJ8 A;  2ODJ A;  3POR A;  1ZHW A;  2Y2X A;  1P4T A;  4FZM A;  5DL7 A;  1THQ A;  5KAF O;  5ADX K;  2M06 A;  3AA0 B;  3DWN A;  4C4V B;  2XE3 A;  3UPG A;  1HXU A;  1GFO A;  3SYB A;  2AXT O;  3AA6 A;  1S5L O;  2W81 C;  5G38 A;  2YNK A;  2XTQ A;  4RLC A;  1QJ9 A;  5GV0 A;  2M07 A;  4JFB A;  4BUM X;  3A2S X;  1HXT A;  5B66 O;  1QJP A;  4K3C A;  3HW9 A;  4LSI A;  4FQE A;  4N75 A;  3FYX A;  3KZI O;  3AAE B;  1T1L A;  2KXP A;  3T0S A;  2O4V A;  2N2M A;  2PRN A;  4N59 A;  4AYI D;  5H2F O;  3POU A;  1T16 A;  4IL6 O;  1E54 A;  4PJ0 O;  3V8U A;  4AYN A;  4JCH A;  4KRA A;  4E1S A;  1G90 A;  1ORM A;  2F1T A;  3AA7 A;  2IWV A;  2KC0 A;  3LK3 B;  3JCU O;  3PGS A;  1OPF A;  4G75 A;  5E79 O;  2KZ7 B;  2ERV A;  3TZG A;  4Z3T A;  5T5F A;  1Q9G A;  3POQ A;  5GTI O;  3SY7 A;  4GF4 A;  2F1C X;  4LSH A;  4O3X B;  5PRN A;  3VE1 A;  3WI5 A;  1MM5 A;  3BRZ A;  4FT6 A;  3DWO X;  2R4N A;  3DA3 A;  4N74 A;  3GP6 A;  3LK2 B;  1BH3 A;  4O3Z A;  3QRA A;  1MM4 A;  4D65 A;  2FGQ X;  4GHB A;  3VE2 A;  5AFU L;  2X27 X;  7PRN A;  2JMM A;  2XMX A;  3K19 A;  3VZU X;  3AAA A;  3KVD D;  4AFK A;  4U9C A;  2R4L A;  3DA4 A;  3PF1 A;  4PR7 A;  2R88 A;  3JTY A;  3VY9 X;  3AA0 A;  3HOL A;  4FUV A;  4C4V A;  5TIS O;  4XNL A;  1BT9 A;  2FGR A;  5DL8 A;  3WU2 O;  1ZHX A;  1HXX A;  2JQY A;  2QTK A;  3AAE A;  3VY8 X;  3HWB A;  4D64 A;  2J4U P;  2XE5 A;  5B5E O;  1H6S 1;  1IZN B;  4RJW A;  3RBH A;  5D5D A;  4AKR B;  2POR A;  3O0E A;  4UB8 O;  2IWW A;  2MHL A;  4FES A;  1ZHY A;  3T24 A;  2KDY A;  4G76 A;  3LK3 A;  5DL5 A;  4PUX A;  2KZ7 A;  3HOE A;  5EE2 A;  4N58 A;  3UU2 A;  1PRN A;  3AA1 B;  4F4B A;  2Y0L A;  1GFQ A;  3DZM A;  3PQU A;  1ZHT A;  2F1V A;  5G39 A;  3LK2 A;  4O49 A;  2Y0H A;  4FSO A;  2WJR A;  3POX A;  4KR8 A;  4O4X A;  4AYD C;  2Y0K A;  3BS0 A;  4CTD A;  4FRT A;  1Q9F A;  5KAI O;  4GCP A;  3SY9 A;  2XTR A;  2XE1 A;  4KR4 A;  3T20 A;  2R89 A;  5AFU K;  2Y7S A;  3A0H O;  2GE4 A;  5JDP A;  3PQS A;  4FRX A;  5ADX L;  4AKM A;  4O3W A;  2R8A A;  4AYE C;  2WJQ A;  3C5O A;  4UB6 O;  1GFN A;  2J1N A;  2K4T A;  4FSP A;  4GCQ A;  4AYM C;  3PRN A;  5G26 A;  3LK4 2;  3BRY A;  2LHF A;  3AA6 B;  3WI4 A;  2R4O A;  4XNK A;  4AUI A;  2XE2 A;  2W80 C;  1BXW A;  3EMN X;  3PGU A;  8PRN A;  1GFP A;  2LFU A;  4GCS A;  4RLB A;  1GFM A;  2ZFG A;  2K0L A;  4QQ1 A;  1IZN A;  4AKR A;  4RJX A;  4E1T A;  4C69 X;  2KXP B;  4B61 A;  6PRN A;  5GTH O;  4FZN A;  4FZL A;  1OSM A;  3VZW X;  1MPF A;  1ZHZ A;  2XG6 A;  3AA1 A;  3AA7 B;  4LSE A;  5G3A A;  3SYS A;  3NJT A;  2OMF A;  2X9K A;  2YPV A;  3QRC A;  4O3Y A;  2MNH A;  3SZV A;  4AZL A;  3NSG A;  3VZT X;  1PHO A;  5DL6 A;  2ZLD A;  4C00 A;  1YS5 A;  3SZD A;  2WVP A;  4FMS A;  5FVN A;  4D5U A;  3LK4 1;  3PGR A;  3A0B O;  2N2L A;  3G7G A; 
#chains in the Genus database with same CATH homology
 4RL9 A;  5IYU A;  4LSF A;  3AAA B;  3UAQ A;  4FOZ A;  3T0S A;  4O4U A;  5DL7 A;  1QJ8 A;  2ODJ A;  3POR A;  1ZHW A;  2Y2X A;  1P4T A;  4FZM A;  4AYN A;  1THQ A;  5ADX K;  2M06 A;  3AA0 B;  3UPG A;  2XE3 A;  1HXU A;  1GFO A;  3SYB A;  3AA6 A;  2W81 C;  2YNK A;  2XTQ A;  4RLC A;  1QJ9 A;  5GV0 A;  2M07 A;  4JFB A;  4BUM X;  3A2S X;  1HXT A;  1QJP A;  4LSI A;  3HW9 A;  3FYX A;  3AAE B;  2KXP A;  2O4V A;  2N2M A;  2PRN A;  4N59 A;  4AYI D;  3POU A;  1G90 A;  4E1S A;  1E54 A;  3V8U A;  4JCH A;  4KRA A;  1ORM A;  2F1T A;  3AA7 A;  4AKM A;  2KC0 A;  3LK3 B;  4C69 X;  1OPF A;  4G75 A;  3TZG A;  2KZ7 B;  2ERV A;  4Z3T A;  5T5F A;  1Q9G A;  3POQ A;  3SY7 A;  4GF4 A;  4LSH A;  4O3X B;  5PRN A;  3VE1 A;  3WI5 A;  3WI4 A;  1MM5 A;  4FT6 A;  3DA3 A;  3GP6 A;  3LK2 B;  1BH3 A;  4O3Z A;  3QRA A;  1MM4 A;  4D65 A;  2FGQ X;  4GHB A;  3VE2 A;  5AFU L;  2X27 X;  7PRN A;  2JMM A;  2XMX A;  3K19 A;  3VZU X;  3AAA A;  3KVD D;  4AFK A;  4U9C A;  3DA4 A;  3JTY A;  3VY9 X;  3AA0 A;  3HOL A;  4FUV A;  4XNL A;  1BT9 A;  2FGR A;  5DL8 A;  1ZHX A;  1HXX A;  2QTK A;  3AAE A;  3VY8 X;  3HWB A;  4D64 A;  2J4U P;  2XE5 A;  1H6S 1;  1IZN B;  4RJW A;  3RBH A;  5D5D A;  4AKR B;  2POR A;  3O0E A;  2MHL A;  4FES A;  1ZHY A;  3T24 A;  2KDY A;  4G76 A;  3LK3 A;  5DL5 A;  4PUX A;  2KZ7 A;  3HOE A;  5EE2 A;  4N58 A;  3UU2 A;  1PRN A;  3AA1 B;  4F4B A;  2Y0L A;  1GFQ A;  3PQU A;  1ZHT A;  2F1V A;  3LK2 A;  4O49 A;  2Y0H A;  4FSO A;  3POX A;  4KR8 A;  4O4X A;  4AYD C;  4B61 A;  2Y0K A;  4FRT A;  1Q9F A;  4GCP A;  3SY9 A;  2XTR A;  2XE1 A;  4KR4 A;  3T20 A;  5AFU K;  2Y7S A;  2GE4 A;  5JDP A;  3PQS A;  4FRX A;  5ADX L;  4O3W A;  4AYE C;  3C5O A;  1GFN A;  2J1N A;  2K4T A;  4FSP A;  4GCQ A;  4AYM C;  3PRN A;  5G26 A;  3LK4 2;  2LHF A;  3AA6 B;  4AUI A;  4XNK A;  2XE2 A;  2W80 C;  1BXW A;  3EMN X;  8PRN A;  1GFP A;  2LFU A;  4GCS A;  4RLB A;  1GFM A;  2ZFG A;  2K0L A;  4QQ1 A;  1IZN A;  4AKR A;  4RJX A;  4E1T A;  2KXP B;  6PRN A;  4FZN A;  4FZL A;  1OSM A;  3VZW X;  1MPF A;  1ZHZ A;  2XG6 A;  3AA1 A;  3AA7 B;  4LSE A;  3SYS A;  2OMF A;  2YPV A;  3QRC A;  4O3Y A;  2MNH A;  3SZV A;  4AZL A;  3NSG A;  3VZT X;  1PHO A;  5DL6 A;  2ZLD A;  1YS5 A;  3SZD A;  4FMS A;  5FVN A;  4D5U A;  3LK4 1;  2N2L A;  3G7G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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