2K4TA

Solution structure of human vdac-1 in ldao micelles
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
285
structure length
285
Chain Sequence
MAVPPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVTGSLETKYRWTEYGLTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGKKNAKIKTGYKREHINLGCDMDFDIAGPSIRGALVLGYEGWLAGYQMNFETAKSRVTQSNFAVGYKTDEFQLHTNVNDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQIDPDACFSAKVNNSSLIGLGYTQTLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQALE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of the integral human membrane protein VDAC-1 in detergent micelles.
pubmed doi rcsb
molecule keywords Voltage-dependent anion-selective channel protein 1
molecule tags Membrane protein,apoptosis
source organism Homo sapiens
total genus 43
structure length 285
sequence length 285
ec nomenclature
pdb deposition date 2008-06-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01459 Porin_3 Eukaryotic porin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.160.10 Mainly Beta Beta Barrel Porin Porin 2k4tA00
3POXA 3VY9X 4RJWA 1GFMA 2QTKA 3T20A 3POUA 4KR8A 3A2SX 6PRNA 3FYXA 3UPGA 3VZTX 1PHOA 4AUIA 3T24A 4D5UA 2K4TA 1GFPA 4KR4A 8PRNA 1E54A 5DL5A 4GCSA 3SYSA 3VY8X 2XE5A 4FT6A 5PRNA 2XE1A 1GFNA 3WI4A 1HXXA 1BT9A 2PRNA 1HXTA 2PORA 4FSOA 5DL7A 2XG6A 1HXUA 4GCPA 1GFQA 3VZWX 4FRTA 4LSHA 3SY9A 1PRNA 3SY7A 4LSEA 3UU2A 4RJXA 7PRNA 5DL6A 4FSPA 3O0EA 4D65A 2Y0LA 1OSMA 3HW9A 1MPFA 4FRXA 3SZDA 4D64A 3NSGA 3HWBA 2XE2A 2Y0KA 5DL8A 4FOZA 2ZLDA 1BH3A 3VZUX 3JTYA 2FGRA 2J4UP 3SYBA 1GFOA 3EMNX 3SZVA 4GCQA 5FVNA 2ODJA 3PRNA 4FMSA 3K19A 3POQA 2O4VA 3PORA 2OMFA 2ZFGA 2Y2XA 2J1NA 4LSIA 2XE3A 4KRAA 4LSFA 1H6S1 4JFBA 2FGQX 3T0SA 3WI5A 4C69X 5JDPA 4BUMX 2Y0HA 1OPFA
chains in the Genus database with same CATH superfamily
4C00A 5H2FO 3AAEB 5B66O 4UB6O 3POXA 4K3CA 3VY9X 4AKRB 4RJWA 1GFMA 2QTKA 3T20A 3POUA 2X27X 3UAQA 4RLCA 2MNHA 2R8AA 4KR8A 3JCUO 1P4TA 3A0HO 3A2SX 3PGRA 2K0LA 3PGSA 6PRNA 3FYXA 3UPGA 2LFUA 3VZTX 1ZHYA 4AYEC 1PHOA 4AUIA 4C4VA 4E1TA 5ADXK 5IYUA 5G26A 3T24A 4O3ZA 1Q9FA 3WU2O 4D5UA 2R4OA 2K4TA 4IL6O 3RBHA 1GFPA 4KR4A 3BRZA 5G39A 2XTRA 8PRNA 1E54A 5DL5A 3BRYA 4GCSA 4N59A 2R88A 1IZNA 4N74A 4O3WA 3SYSA 3VY8X 5B5EO 3LK2A 4N75A 2XE5A 2IWVA 4FT6A 2KC0A 3PQSA 4G75A 4XNLA 5PRNA 2XE1A 4AZLA 1GFNA 4PJ0O 2X9KA 3WI4A 4AYNA 1HXXA 3AA1B 1ZHWA 2ERVA 3AA0B 3GP6A 4FZMA 2R4LA 4O4XA 5G38A 1BT9A 4PR7A 3QRCA 4O3XB 3AAEA 2PRNA 1HXTA 3G7GA 5T5FA 5TISO 2R4NA 2W80C 2PORA 2KZ7B 4FSOA 4JCHA 2WVPA 3AA1A 3DA3A 4U9CA 4O3YA 4AKRA 5DL7A 2XG6A 1HXUA 3LK41 1MM5A 2KDYA 2R4PA 4GCPA 4GHBA 4QQ1A 1BXWA 1GFQA 3HOEA 3VZWX 4FRTA 4LSHA 4AYDC 5AFUK 2R89A 1PRNA 3SY9A 2YNKA 3SY7A 4LSEA 3UU2A 4RJXA 4N58A 1ZHZA 5DL6A 2JMMA 7PRNA 3LK3B 4FSPA 2YPVA 3DA4A 3O0EA 4D65A 2Y0LA 3AA6B 4GF4A 1OSMA 3AA7B 3HW9A 1S5LO 2W81C 3KVDD 2N2LA 3PF1A 1MPFA 2WJRA 1T1LA 4FRXA 5EE2A 3SZDA 4D64A 4O49A 2M07A 3VE2A 2F1TA 3NSGA 5GV0A 3HWBA 3V8UA 3NJTA 4AKMA 2XE2A 3QRAA 2N2MA 2Y0KA 2KXPB 5ADXL 5DL8A 2F1CX 2LHFA 1QJ9A 5KAFO 1QJ8A 2ZLDA 4FOZA 2IWWA 2MHLA 2XTQA 3AAAB 3VE1A 4UB8O 2Y7SA 3AA0A 3C5OA 4CTDA 1BH3A 4B61A 2XMXA 3VZUX 1MM4A 3JTYA 1ZHTA 2FGRA 2J4UP 1Q9GA 2KZ7A 3KZIO 4FQEA 4XNKA 4FESA 4FZLA 1QJPA 3SYBA 1GFOA 3DWNA 1THQA 2JQYA 3EMNX 2WJQA 3LK42 4O4UA 4GCQA 3SZVA 5FVNA 2ODJA 4AYMC 3PRNA 4FMSA 3TZGA 4E1SA 1G90A 3K19A 2GE4A 2AXTO 3POQA 5E79O 5KAIO 2O4VA 3PGUA 4C4VB 3BS0A 3PORA 2OMFA 3DWOX 4FZNA 3LK3A 4PUXA 1ORMA 4G76A 5D5DA 4AFKA 4Z3TA 3AA6A 2ZFGA 2F1VA 2Y2XA 3AA7A 4AYID 2J1NA 3DZMA 4F4BA 4LSIA 5AFUL 5GTHO 1IZNB 2XE3A 3LK2B 1ZHXA 4KRAA 4LSFA 3HOLA 1H6S1 4JFBA 1T16A 4RL9A 2FGQX 3T0SA 2KXPA 4FUVA 3WI5A 4C69X 1YS5A 5GTIO 5G3AA 5JDPA 4BUMX 3PQUA 2Y0HA 4K3BA 3A0BO 3AAAA 1OPFA 2M06A 4RLBA
chains in the Genus database with same CATH topology
3AAEB 3POXA 3VY9X 4AKRB 4RJWA 1GFMA 2QTKA 3T20A 3POUA 2X27X 3UAQA 4RLCA 2MNHA 4KR8A 1P4TA 3A2SX 2K0LA 6PRNA 3FYXA 3UPGA 2LFUA 3VZTX 1ZHYA 4AYEC 1PHOA 4AUIA 4E1TA 5ADXK 5IYUA 5G26A 3T24A 4O3ZA 1Q9FA 4D5UA 2K4TA 3RBHA 1GFPA 4KR4A 2XTRA 8PRNA 1E54A 5DL5A 4GCSA 4N59A 3SYSA 1IZNA 4O3WA 3VY8X 3LK2A 2XE5A 4FT6A 4G75A 2KC0A 3PQSA 4XNLA 5PRNA 4AZLA 2XE1A 1GFNA 3WI4A 4AYNA 1HXXA 3AA1B 1ZHWA 2ERVA 3AA0B 3GP6A 4FZMA 4O4XA 1BT9A 3QRCA 4O3XB 3AAEA 2PRNA 1HXTA 3G7GA 5T5FA 2W80C 2PORA 2KZ7B 4FSOA 4JCHA 3AA1A 4U9CA 3DA3A 4AKRA 4O3YA 5DL7A 2XG6A 1HXUA 3LK41 1MM5A 2KDYA 4GHBA 4GCPA 4QQ1A 1BXWA 1GFQA 3HOEA 3VZWX 4FRTA 4LSHA 4AYDC 5AFUK 3SY9A 1PRNA 2YNKA 3SY7A 4LSEA 3UU2A 4RJXA 4N58A 1ZHZA 5DL6A 2JMMA 7PRNA 3LK3B 4FSPA 2YPVA 3DA4A 3O0EA 4D65A 2Y0LA 3AA6B 4GF4A 1OSMA 3AA7B 3HW9A 2W81C 3KVDD 2N2LA 1MPFA 4FRXA 3SZDA 5EE2A 4D64A 4O49A 2M07A 3VE2A 2F1TA 3NSGA 5GV0A 3HWBA 3V8UA 4AKMA 2XE2A 3QRAA 2N2MA 2Y0KA 2KXPB 5ADXL 5DL8A 2LHFA 1QJ9A 1QJ8A 2ZLDA 4FOZA 2MHLA 2XTQA 3AAAB 3VE1A 2Y7SA 3AA0A 3C5OA 1BH3A 4B61A 2XMXA 3VZUX 1MM4A 3JTYA 1ZHTA 2FGRA 2J4UP 1Q9GA 2KZ7A 4XNKA 4FESA 4FZLA 1QJPA 3SYBA 1GFOA 4O4UA 1THQA 3EMNX 3LK42 3SZVA 4GCQA 5FVNA 2ODJA 4AYMC 3PRNA 4FMSA 3TZGA 4E1SA 1G90A 3K19A 2GE4A 3POQA 2O4VA 3PORA 2OMFA 4PUXA 4FZNA 3LK3A 5D5DA 1ORMA 4G76A 4AFKA 4Z3TA 3AA6A 2ZFGA 2F1VA 2Y2XA 3AA7A 4AYID 2J1NA 4F4BA 4LSIA 5AFUL 1IZNB 2XE3A 3LK2B 1ZHXA 4KRAA 4LSFA 3HOLA 1H6S1 4JFBA 4RL9A 2FGQX 3T0SA 2KXPA 4FUVA 3WI5A 4C69X 1YS5A 5JDPA 4BUMX 3PQUA 2Y0HA 3AAAA 1OPFA 2M06A 4RLBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3POX A;  3VY9 X;  4RJW A;  1GFM A;  2QTK A;  3T20 A;  3POU A;  4KR8 A;  3A2S X;  6PRN A;  3FYX A;  3UPG A;  3VZT X;  1PHO A;  4AUI A;  3T24 A;  4D5U A;  2K4T A;  1GFP A;  4KR4 A;  8PRN A;  1E54 A;  5DL5 A;  4GCS A;  3SYS A;  3VY8 X;  2XE5 A;  4FT6 A;  5PRN A;  2XE1 A;  1GFN A;  3WI4 A;  1HXX A;  1BT9 A;  2PRN A;  1HXT A;  2POR A;  4FSO A;  5DL7 A;  2XG6 A;  1HXU A;  4GCP A;  1GFQ A;  3VZW X;  4FRT A;  4LSH A;  3SY9 A;  1PRN A;  3SY7 A;  4LSE A;  3UU2 A;  4RJX A;  7PRN A;  5DL6 A;  4FSP A;  3O0E A;  4D65 A;  2Y0L A;  1OSM A;  3HW9 A;  1MPF A;  4FRX A;  3SZD A;  4D64 A;  3NSG A;  3HWB A;  2XE2 A;  2Y0K A;  5DL8 A;  4FOZ A;  2ZLD A;  1BH3 A;  3VZU X;  3JTY A;  2FGR A;  2J4U P;  3SYB A;  1GFO A;  3EMN X;  3SZV A;  4GCQ A;  5FVN A;  2ODJ A;  3PRN A;  4FMS A;  3K19 A;  3POQ A;  2O4V A;  3POR A;  2OMF A;  2ZFG A;  2Y2X A;  2J1N A;  4LSI A;  2XE3 A;  4KRA A;  4LSF A;  1H6S 1;  4JFB A;  2FGQ X;  3T0S A;  3WI5 A;  4C69 X;  5JDP A;  4BUM X;  2Y0H A;  1OPF A; 
#chains in the Genus database with same CATH topology
 4C00 A;  5H2F O;  3AAE B;  5B66 O;  4UB6 O;  3POX A;  4K3C A;  3VY9 X;  4AKR B;  4RJW A;  1GFM A;  2QTK A;  3T20 A;  3POU A;  2X27 X;  3UAQ A;  4RLC A;  2MNH A;  2R8A A;  4KR8 A;  3JCU O;  1P4T A;  3A0H O;  3A2S X;  3PGR A;  2K0L A;  3PGS A;  6PRN A;  3FYX A;  3UPG A;  2LFU A;  3VZT X;  1ZHY A;  4AYE C;  1PHO A;  4AUI A;  4C4V A;  4E1T A;  5ADX K;  5IYU A;  5G26 A;  3T24 A;  4O3Z A;  1Q9F A;  3WU2 O;  4D5U A;  2R4O A;  2K4T A;  4IL6 O;  3RBH A;  1GFP A;  4KR4 A;  3BRZ A;  5G39 A;  2XTR A;  8PRN A;  1E54 A;  5DL5 A;  3BRY A;  4GCS A;  4N59 A;  2R88 A;  1IZN A;  4N74 A;  4O3W A;  3SYS A;  3VY8 X;  5B5E O;  3LK2 A;  4N75 A;  2XE5 A;  2IWV A;  4FT6 A;  2KC0 A;  3PQS A;  4G75 A;  4XNL A;  5PRN A;  2XE1 A;  4AZL A;  1GFN A;  4PJ0 O;  2X9K A;  3WI4 A;  4AYN A;  1HXX A;  3AA1 B;  1ZHW A;  2ERV A;  3AA0 B;  3GP6 A;  4FZM A;  2R4L A;  4O4X A;  5G38 A;  1BT9 A;  4PR7 A;  3QRC A;  4O3X B;  3AAE A;  2PRN A;  1HXT A;  3G7G A;  5T5F A;  5TIS O;  2R4N A;  2W80 C;  2POR A;  2KZ7 B;  4FSO A;  4JCH A;  2WVP A;  3AA1 A;  3DA3 A;  4U9C A;  4O3Y A;  4AKR A;  5DL7 A;  2XG6 A;  1HXU A;  3LK4 1;  1MM5 A;  2KDY A;  2R4P A;  4GCP A;  4GHB A;  4QQ1 A;  1BXW A;  1GFQ A;  3HOE A;  3VZW X;  4FRT A;  4LSH A;  4AYD C;  5AFU K;  2R89 A;  1PRN A;  3SY9 A;  2YNK A;  3SY7 A;  4LSE A;  3UU2 A;  4RJX A;  4N58 A;  1ZHZ A;  5DL6 A;  2JMM A;  7PRN A;  3LK3 B;  4FSP A;  2YPV A;  3DA4 A;  3O0E A;  4D65 A;  2Y0L A;  3AA6 B;  4GF4 A;  1OSM A;  3AA7 B;  3HW9 A;  1S5L O;  2W81 C;  3KVD D;  2N2L A;  3PF1 A;  1MPF A;  2WJR A;  1T1L A;  4FRX A;  5EE2 A;  3SZD A;  4D64 A;  4O49 A;  2M07 A;  3VE2 A;  2F1T A;  3NSG A;  5GV0 A;  3HWB A;  3V8U A;  3NJT A;  4AKM A;  2XE2 A;  3QRA A;  2N2M A;  2Y0K A;  2KXP B;  5ADX L;  5DL8 A;  2F1C X;  2LHF A;  1QJ9 A;  5KAF O;  1QJ8 A;  2ZLD A;  4FOZ A;  2IWW A;  2MHL A;  2XTQ A;  3AAA B;  3VE1 A;  4UB8 O;  2Y7S A;  3AA0 A;  3C5O A;  4CTD A;  1BH3 A;  4B61 A;  2XMX A;  3VZU X;  1MM4 A;  3JTY A;  1ZHT A;  2FGR A;  2J4U P;  1Q9G A;  2KZ7 A;  3KZI O;  4FQE A;  4XNK A;  4FES A;  4FZL A;  1QJP A;  3SYB A;  1GFO A;  3DWN A;  1THQ A;  2JQY A;  3EMN X;  2WJQ A;  3LK4 2;  4O4U A;  4GCQ A;  3SZV A;  5FVN A;  2ODJ A;  4AYM C;  3PRN A;  4FMS A;  3TZG A;  4E1S A;  1G90 A;  3K19 A;  2GE4 A;  2AXT O;  3POQ A;  5E79 O;  5KAI O;  2O4V A;  3PGU A;  4C4V B;  3BS0 A;  3POR A;  2OMF A;  3DWO X;  4FZN A;  3LK3 A;  4PUX A;  1ORM A;  4G76 A;  5D5D A;  4AFK A;  4Z3T A;  3AA6 A;  2ZFG A;  2F1V A;  2Y2X A;  3AA7 A;  4AYI D;  2J1N A;  3DZM A;  4F4B A;  4LSI A;  5AFU L;  5GTH O;  1IZN B;  2XE3 A;  3LK2 B;  1ZHX A;  4KRA A;  4LSF A;  3HOL A;  1H6S 1;  4JFB A;  1T16 A;  4RL9 A;  2FGQ X;  3T0S A;  2KXP A;  4FUV A;  3WI5 A;  4C69 X;  1YS5 A;  5GTI O;  5G3A A;  5JDP A;  4BUM X;  3PQU A;  2Y0H A;  4K3B A;  3A0B O;  3AAA A;  1OPF A;  2M06 A;  4RLB A; 
#chains in the Genus database with same CATH homology
 3AAE B;  3POX A;  3VY9 X;  4AKR B;  4RJW A;  1GFM A;  2QTK A;  3T20 A;  3POU A;  2X27 X;  3UAQ A;  4RLC A;  2MNH A;  4KR8 A;  1P4T A;  3A2S X;  2K0L A;  6PRN A;  3FYX A;  3UPG A;  2LFU A;  3VZT X;  1ZHY A;  4AYE C;  1PHO A;  4AUI A;  4E1T A;  5ADX K;  5IYU A;  5G26 A;  3T24 A;  4O3Z A;  1Q9F A;  4D5U A;  2K4T A;  3RBH A;  1GFP A;  4KR4 A;  2XTR A;  8PRN A;  1E54 A;  5DL5 A;  4GCS A;  4N59 A;  3SYS A;  1IZN A;  4O3W A;  3VY8 X;  3LK2 A;  2XE5 A;  4FT6 A;  4G75 A;  2KC0 A;  3PQS A;  4XNL A;  5PRN A;  4AZL A;  2XE1 A;  1GFN A;  3WI4 A;  4AYN A;  1HXX A;  3AA1 B;  1ZHW A;  2ERV A;  3AA0 B;  3GP6 A;  4FZM A;  4O4X A;  1BT9 A;  3QRC A;  4O3X B;  3AAE A;  2PRN A;  1HXT A;  3G7G A;  5T5F A;  2W80 C;  2POR A;  2KZ7 B;  4FSO A;  4JCH A;  3AA1 A;  4U9C A;  3DA3 A;  4AKR A;  4O3Y A;  5DL7 A;  2XG6 A;  1HXU A;  3LK4 1;  1MM5 A;  2KDY A;  4GHB A;  4GCP A;  4QQ1 A;  1BXW A;  1GFQ A;  3HOE A;  3VZW X;  4FRT A;  4LSH A;  4AYD C;  5AFU K;  3SY9 A;  1PRN A;  2YNK A;  3SY7 A;  4LSE A;  3UU2 A;  4RJX A;  4N58 A;  1ZHZ A;  5DL6 A;  2JMM A;  7PRN A;  3LK3 B;  4FSP A;  2YPV A;  3DA4 A;  3O0E A;  4D65 A;  2Y0L A;  3AA6 B;  4GF4 A;  1OSM A;  3AA7 B;  3HW9 A;  2W81 C;  3KVD D;  2N2L A;  1MPF A;  4FRX A;  3SZD A;  5EE2 A;  4D64 A;  4O49 A;  2M07 A;  3VE2 A;  2F1T A;  3NSG A;  5GV0 A;  3HWB A;  3V8U A;  4AKM A;  2XE2 A;  3QRA A;  2N2M A;  2Y0K A;  2KXP B;  5ADX L;  5DL8 A;  2LHF A;  1QJ9 A;  1QJ8 A;  2ZLD A;  4FOZ A;  2MHL A;  2XTQ A;  3AAA B;  3VE1 A;  2Y7S A;  3AA0 A;  3C5O A;  1BH3 A;  4B61 A;  2XMX A;  3VZU X;  1MM4 A;  3JTY A;  1ZHT A;  2FGR A;  2J4U P;  1Q9G A;  2KZ7 A;  4XNK A;  4FES A;  4FZL A;  1QJP A;  3SYB A;  1GFO A;  4O4U A;  1THQ A;  3EMN X;  3LK4 2;  3SZV A;  4GCQ A;  5FVN A;  2ODJ A;  4AYM C;  3PRN A;  4FMS A;  3TZG A;  4E1S A;  1G90 A;  3K19 A;  2GE4 A;  3POQ A;  2O4V A;  3POR A;  2OMF A;  4PUX A;  4FZN A;  3LK3 A;  5D5D A;  1ORM A;  4G76 A;  4AFK A;  4Z3T A;  3AA6 A;  2ZFG A;  2F1V A;  2Y2X A;  3AA7 A;  4AYI D;  2J1N A;  4F4B A;  4LSI A;  5AFU L;  1IZN B;  2XE3 A;  3LK2 B;  1ZHX A;  4KRA A;  4LSF A;  3HOL A;  1H6S 1;  4JFB A;  4RL9 A;  2FGQ X;  3T0S A;  2KXP A;  4FUV A;  3WI5 A;  4C69 X;  1YS5 A;  5JDP A;  4BUM X;  3PQU A;  2Y0H A;  3AAA A;  1OPF A;  2M06 A;  4RLB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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