2K7XA

Solution structure of c-terminal domain of sars-cov main protease
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
120
structure length
120
Chain Sequence
DRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title C-terminal domain of SARS-CoV main protease can form a 3D domain-swapped dimer.
pubmed doi rcsb
molecule keywords SARS-CoV main protease
molecule tags Hydrolase
source organism Sars coronavirus
total genus 37
structure length 120
sequence length 120
ec nomenclature
pdb deposition date 2008-08-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1840.10 Mainly Alpha Orthogonal Bundle main proteinase (3clpro) structure, domain 3 main proteinase (3clpro) structure, domain 3 2k7xA00
3VB3A 4TWWA 3SNDA 3SNCA 3SN8A 4ZUHA 4MDSA 2YNAA 3E91A 4HI3A 3V3MA 5HYOA 2BX4A 1UK4A 3SNEA 4YOGA 3TITA 4TWYA 2GZ8A 2Z9KA 2Z3CA 2GT8A 2Z3EA 2ZU5A 3VB6A 2QC2A 5C3NA 1UK2A 2ZU2A 2GZ9A 2GZ7A 2H2ZA 3VB4A 1LVOA 2QCYA 2AMDA 1Q2WA 3M3VA 3M3SA 3TNSA 2DUCA 1UK3A 2Z9LA 2LIZA 2Q6FA 4F49A 2GX4A 2ZU4A 2D2DA 3VB7A 2GTBA 4YOIA 2ALVA 2YNBA 5GWZA 4RSPA 2VJ1A 3SNBA 3ATWA 3SZNA 2Z9JA 4WY3A 3AW0A 3TLOA 5EU8A 3EAJA 2Z3DA 1P9SA 4YO9A 5B6OA 1Z1IA 2K7XA 2HOBA 5C5NA 3SNAA 3M3TA 2Q6GA 4WMEA 1P9UA 2QIQA 4YOJA 3EA7A 3AW1A 2PWXA 2Q6DA 3EA8A 2V6NA 3D23A 4WMDA 2A5IA 2C3SA 2AMPA 3F9FA 2A5KA 3EBNA 5C5OA 2BX3A 2Z94A 2A5AA 3TNTA 3VB5A 3D62A 4YLUA 1WOFA 4WMFA 3F9HA 1Z1JA 4XFQA 4ZROA 2Z9GA 3EA9A 2OP9A 3AVZA 3FZDA 3IWMA 3F9EA 3F9GA 3TIUA 2AMQA 2GT7A 1UJ1A
chains in the Genus database with same CATH superfamily
3VB3A 4TWWA 3SNDA 3SNCA 3SN8A 4ZUHA 4MDSA 2YNAA 3E91A 4HI3A 3V3MA 5HYOA 2BX4A 1UK4A 3SNEA 4YOGA 3TITA 4TWYA 2GZ8A 2Z9KA 2Z3CA 2GT8A 2Z3EA 2ZU5A 3VB6A 2QC2A 5C3NA 1UK2A 2ZU2A 2GZ9A 2GZ7A 2H2ZA 3VB4A 1LVOA 2QCYA 2AMDA 1Q2WA 3M3VA 3M3SA 3TNSA 2DUCA 1UK3A 2Z9LA 2LIZA 2Q6FA 4F49A 2GX4A 2ZU4A 2D2DA 3VB7A 2GTBA 4YOIA 2ALVA 2YNBA 5GWZA 4RSPA 2VJ1A 3SNBA 3ATWA 3SZNA 2Z9JA 4WY3A 3AW0A 3TLOA 5EU8A 3EAJA 2Z3DA 1P9SA 4YO9A 5B6OA 1Z1IA 2K7XA 2HOBA 5C5NA 3SNAA 3M3TA 2Q6GA 4WMEA 1P9UA 2QIQA 4YOJA 3EA7A 3AW1A 2PWXA 2Q6DA 3EA8A 2V6NA 3D23A 4WMDA 2A5IA 2C3SA 2AMPA 3F9FA 2A5KA 3EBNA 5C5OA 2BX3A 2Z94A 2A5AA 3TNTA 3VB5A 3D62A 4YLUA 1WOFA 4WMFA 3F9HA 1Z1JA 4XFQA 4ZROA 2Z9GA 3EA9A 2OP9A 3AVZA 3FZDA 3IWMA 3F9EA 3F9GA 3TIUA 2AMQA 2GT7A 1UJ1A
chains in the Genus database with same CATH topology
3VB3A 4TWWA 3SNDA 3SNCA 3SN8A 4ZUHA 4MDSA 2YNAA 3E91A 4HI3A 3V3MA 5HYOA 2BX4A 1UK4A 3SNEA 4YOGA 3TITA 4TWYA 2GZ8A 2Z9KA 2Z3CA 2GT8A 2Z3EA 2ZU5A 3VB6A 2QC2A 5C3NA 1UK2A 2ZU2A 2GZ9A 2GZ7A 2H2ZA 3VB4A 1LVOA 2QCYA 2AMDA 1Q2WA 3M3VA 3M3SA 3TNSA 2DUCA 1UK3A 2Z9LA 2LIZA 2Q6FA 4F49A 2GX4A 2ZU4A 2D2DA 3VB7A 2GTBA 4YOIA 2ALVA 2YNBA 5GWZA 4RSPA 2VJ1A 3SNBA 3ATWA 3SZNA 2Z9JA 4WY3A 3AW0A 3TLOA 5EU8A 3EAJA 2Z3DA 1P9SA 4YO9A 5B6OA 1Z1IA 2K7XA 2HOBA 5C5NA 3SNAA 3M3TA 2Q6GA 4WMEA 1P9UA 2QIQA 4YOJA 3EA7A 3AW1A 2PWXA 2Q6DA 3EA8A 2V6NA 3D23A 4WMDA 2A5IA 2C3SA 2AMPA 3F9FA 2A5KA 3EBNA 5C5OA 2BX3A 2Z94A 2A5AA 3TNTA 3VB5A 3D62A 4YLUA 1WOFA 4WMFA 3F9HA 1Z1JA 4XFQA 4ZROA 2Z9GA 3EA9A 2OP9A 3AVZA 3FZDA 3IWMA 3F9EA 3F9GA 3TIUA 2AMQA 2GT7A 1UJ1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3VB3 A;  4TWW A;  3SND A;  3SNC A;  3SN8 A;  4ZUH A;  4MDS A;  2YNA A;  3E91 A;  4HI3 A;  3V3M A;  5HYO A;  2BX4 A;  1UK4 A;  3SNE A;  4YOG A;  3TIT A;  4TWY A;  2GZ8 A;  2Z9K A;  2Z3C A;  2GT8 A;  2Z3E A;  2ZU5 A;  3VB6 A;  2QC2 A;  5C3N A;  1UK2 A;  2ZU2 A;  2GZ9 A;  2GZ7 A;  2H2Z A;  3VB4 A;  1LVO A;  2QCY A;  2AMD A;  1Q2W A;  3M3V A;  3M3S A;  3TNS A;  2DUC A;  1UK3 A;  2Z9L A;  2LIZ A;  2Q6F A;  4F49 A;  2GX4 A;  2ZU4 A;  2D2D A;  3VB7 A;  2GTB A;  4YOI A;  2ALV A;  2YNB A;  5GWZ A;  4RSP A;  2VJ1 A;  3SNB A;  3ATW A;  3SZN A;  2Z9J A;  4WY3 A;  3AW0 A;  3TLO A;  5EU8 A;  3EAJ A;  2Z3D A;  1P9S A;  4YO9 A;  5B6O A;  1Z1I A;  2K7X A;  2HOB A;  5C5N A;  3SNA A;  3M3T A;  2Q6G A;  4WME A;  1P9U A;  2QIQ A;  4YOJ A;  3EA7 A;  3AW1 A;  2PWX A;  2Q6D A;  3EA8 A;  2V6N A;  3D23 A;  4WMD A;  2A5I A;  2C3S A;  2AMP A;  3F9F A;  2A5K A;  3EBN A;  5C5O A;  2BX3 A;  2Z94 A;  2A5A A;  3TNT A;  3VB5 A;  3D62 A;  4YLU A;  1WOF A;  4WMF A;  3F9H A;  1Z1J A;  4XFQ A;  4ZRO A;  2Z9G A;  3EA9 A;  2OP9 A;  3AVZ A;  3FZD A;  3IWM A;  3F9E A;  3F9G A;  3TIU A;  2AMQ A;  2GT7 A;  1UJ1 A; 
#chains in the Genus database with same CATH topology
 3VB3 A;  4TWW A;  3SND A;  3SNC A;  3SN8 A;  4ZUH A;  4MDS A;  2YNA A;  3E91 A;  4HI3 A;  3V3M A;  5HYO A;  2BX4 A;  1UK4 A;  3SNE A;  4YOG A;  3TIT A;  4TWY A;  2GZ8 A;  2Z9K A;  2Z3C A;  2GT8 A;  2Z3E A;  2ZU5 A;  3VB6 A;  2QC2 A;  5C3N A;  1UK2 A;  2ZU2 A;  2GZ9 A;  2GZ7 A;  2H2Z A;  3VB4 A;  1LVO A;  2QCY A;  2AMD A;  1Q2W A;  3M3V A;  3M3S A;  3TNS A;  2DUC A;  1UK3 A;  2Z9L A;  2LIZ A;  2Q6F A;  4F49 A;  2GX4 A;  2ZU4 A;  2D2D A;  3VB7 A;  2GTB A;  4YOI A;  2ALV A;  2YNB A;  5GWZ A;  4RSP A;  2VJ1 A;  3SNB A;  3ATW A;  3SZN A;  2Z9J A;  4WY3 A;  3AW0 A;  3TLO A;  5EU8 A;  3EAJ A;  2Z3D A;  1P9S A;  4YO9 A;  5B6O A;  1Z1I A;  2K7X A;  2HOB A;  5C5N A;  3SNA A;  3M3T A;  2Q6G A;  4WME A;  1P9U A;  2QIQ A;  4YOJ A;  3EA7 A;  3AW1 A;  2PWX A;  2Q6D A;  3EA8 A;  2V6N A;  3D23 A;  4WMD A;  2A5I A;  2C3S A;  2AMP A;  3F9F A;  2A5K A;  3EBN A;  5C5O A;  2BX3 A;  2Z94 A;  2A5A A;  3TNT A;  3VB5 A;  3D62 A;  4YLU A;  1WOF A;  4WMF A;  3F9H A;  1Z1J A;  4XFQ A;  4ZRO A;  2Z9G A;  3EA9 A;  2OP9 A;  3AVZ A;  3FZD A;  3IWM A;  3F9E A;  3F9G A;  3TIU A;  2AMQ A;  2GT7 A;  1UJ1 A; 
#chains in the Genus database with same CATH homology
 3VB3 A;  4TWW A;  3SND A;  3SNC A;  3SN8 A;  4ZUH A;  4MDS A;  2YNA A;  3E91 A;  4HI3 A;  3V3M A;  5HYO A;  2BX4 A;  1UK4 A;  3SNE A;  4YOG A;  3TIT A;  4TWY A;  2GZ8 A;  2Z9K A;  2Z3C A;  2GT8 A;  2Z3E A;  2ZU5 A;  3VB6 A;  2QC2 A;  5C3N A;  1UK2 A;  2ZU2 A;  2GZ9 A;  2GZ7 A;  2H2Z A;  3VB4 A;  1LVO A;  2QCY A;  2AMD A;  1Q2W A;  3M3V A;  3M3S A;  3TNS A;  2DUC A;  1UK3 A;  2Z9L A;  2LIZ A;  2Q6F A;  4F49 A;  2GX4 A;  2ZU4 A;  2D2D A;  3VB7 A;  2GTB A;  4YOI A;  2ALV A;  2YNB A;  5GWZ A;  4RSP A;  2VJ1 A;  3SNB A;  3ATW A;  3SZN A;  2Z9J A;  4WY3 A;  3AW0 A;  3TLO A;  5EU8 A;  3EAJ A;  2Z3D A;  1P9S A;  4YO9 A;  5B6O A;  1Z1I A;  2K7X A;  2HOB A;  5C5N A;  3SNA A;  3M3T A;  2Q6G A;  4WME A;  1P9U A;  2QIQ A;  4YOJ A;  3EA7 A;  3AW1 A;  2PWX A;  2Q6D A;  3EA8 A;  2V6N A;  3D23 A;  4WMD A;  2A5I A;  2C3S A;  2AMP A;  3F9F A;  2A5K A;  3EBN A;  5C5O A;  2BX3 A;  2Z94 A;  2A5A A;  3TNT A;  3VB5 A;  3D62 A;  4YLU A;  1WOF A;  4WMF A;  3F9H A;  1Z1J A;  4XFQ A;  4ZRO A;  2Z9G A;  3EA9 A;  2OP9 A;  3AVZ A;  3FZD A;  3IWM A;  3F9E A;  3F9G A;  3TIU A;  2AMQ A;  2GT7 A;  1UJ1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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