2KBRA

Solution structure of harmonin n terminal domain in complex with a internal peptide of cadherin23
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
80
structure length
80
Chain Sequence
MDRKVAREFRHKVDFLIENDAEKDYLYDVLRMYHQTMDVAVLVGDLKLVINEPSRLPLFDAIRPLIPLKHQVEYDQLTPR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Structural protein/cell adhesion
molecule keywords Harmonin
publication title Assembling stable hair cell tip link complex via multidentate interactions between harmonin and cadherin 23
pubmed doi rcsb
source organism Homo sapiens
total genus 26
structure length 80
sequence length 80
ec nomenclature
pdb deposition date 2008-12-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1160.20 Mainly Alpha Up-down Bundle Paired amphipathic helix 2 (pah2 repeat) Paired amphipathic helix 2 (pah2 repeat) 2kbrA00
4Y5OA 2KBRA 5F3XA 4YKDA 4YKCA 3K1RA 4YL6A 2KBQA 2LSRA 4FQNA
chains in the Genus database with same CATH superfamily
4Y5OA 2KBRA 3K1RA 4YL6A 2LSRA 4FQNA 2L9SB 2RMRA 2LD7B 1E91A 1PD7A 1S5RB 1G1EB 2CZYA 5F3XA 2CR7A 4YKCA 1S5QB 2RMSA 4YKDA 2KBQA 2F05A
chains in the Genus database with same CATH topology
4Y5OA 2KBRA 5F3XA 4YKDA 4YKCA 3K1RA 4YL6A 2KBQA 2LSRA 4FQNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Y5O A;  2KBR A;  5F3X A;  4YKD A;  4YKC A;  3K1R A;  4YL6 A;  2KBQ A;  2LSR A;  4FQN A; 
#chains in the Genus database with same CATH topology
 4Y5O A;  2KBR A;  3K1R A;  4YL6 A;  2LSR A;  4FQN A;  2L9S B;  2RMR A;  2LD7 B;  1E91 A;  1PD7 A;  1S5R B;  1G1E B;  2CZY A;  5F3X A;  2CR7 A;  4YKC A;  1S5Q B;  2RMS A;  4YKD A;  2KBQ A;  2F05 A; 
#chains in the Genus database with same CATH homology
 4Y5O A;  2KBR A;  5F3X A;  4YKD A;  4YKC A;  3K1R A;  4YL6 A;  2KBQ A;  2LSR A;  4FQN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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