2KG8A

Nmr solution structures of malonyl acp from the actinorhodin polyketide synthase in streptomyces coelicolor
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
86
structure length
86
Chain Sequence
MATLLTTDDLRRALVESAGETDGTDLSGDFLDLRFEDIGYDSLALMETAARLESRYGVSIPDDVAGRVDTPRELLDLINGALAEAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2).
pubmed doi rcsb
source organism Streptomyces coelicolor
molecule tags Biosynthetic protein
molecule keywords Actinorhodin polyketide synthase acyl carrier protein
total genus 25
structure length 86
sequence length 86
ec nomenclature
pdb deposition date 2009-03-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00550 PP-binding Phosphopantetheine attachment site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1200.10 Mainly Alpha Orthogonal Bundle Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A ACP-like 2kg8A00
2CNRA 2ROQA 3EJBA 2KOOA 2CG5B 1VKUA 4DG9A 3EJDA 2N98A 2VSQA 4CA3A 2LIUA 1NQ4A 4BPHA 2JQ4A 2MR8A 2MD9A 1ACPA 2N5HA 2FACA 2DNWA 2AFDA 2N6ZA 2KGDA 2LTEA 4PWVB 2JU2A 3NY7B 4BPGA 2LIWA 2KORA 4BPFA 2L0QA 2GDYA 2K0YA 2AF8A 2FVEA 2N6YA 5EJDA 1T8KA 1HY8A 3GZLA 4MRTC 2FHSC 2AFEA 2KOQA 2FQ0A 2PNGA 4R0MA 2JU1A 2L4BA 2LOLA 2FQ2A 2L22A 2KGAA 2LL8A 2KWLA 3EJEA 3RG2A 4IZ6A 2JGPA 2CQ8A 2KG6A 2X2BA 1L0IA 2K94A 4HKGA 1F80D 2KR5A 2K0XA 2EHTA 2L9FA 1DNYA 1DV5A 2KW2A 2LMLA 2EHSA 2QNWA 2K93A 5KP6B 3GZMA 2FVAA 3CE7A 2M5RA 2FVFA 2MVUA 2GDWA 2N5IA 1AF8A 1OR5A 1HQBA 2K92A 2XZ1C 2CGQA 2MY5A 1X3OA 2GDXA 2LPKA 2MVVA 2K2QA 2N50A 5KP7B 2KGEA 2AVAA 2KOPA 5HV8A 5HVCA 2KOSA 5CZDB 2KG8A 1L0HA 2MR7A 2FADA 4H2XC 2XZ0D 3LMOA 2FQ1A 4H2WC 2LKIA 1KLPA 4H2YC 2KGCA 2FAEA 5KP8B 2KG9A 4NEOA 4PXHB 2MF4A
chains in the Genus database with same CATH superfamily
1A43A 2KOOA 1YJ9P 2CG5B 1Z6MA 2N98A 4BPHA 1K9MQ 2ERHA 2PEQA 3DS5A 1ACPA 1K8AQ 2AFDA 1GXHA 5DCKA 4PWVB 3RG6C 2JU2A 1VQPP 1Q82Q 4BPGA 4BPFA 4PH1A 3B5IA 3HZQA 5EJDA 4QNBA 4U0FA 1KQSO 3GZLA 2FHSC 3HYBA 4R0MA 2JU1A 3DTJA 2Z45A 2JAZA 2KODA 2EFJA 3NTEA 4IZ6A 1VQKP 2CQ8A 3DS0A 3LRYA 2GZIA 2X2BA 3DPHA 1FR2A 1KD1Q 3CCUP 3G6EP 2M8PA 1DNYA 1KC8Q 3CCMP 3CD6P 5KP6B 3GZMA 2FVAA 2M5RA 2MVUA 1W2BO 2N5IA 1AF8A 1OR5A 2K92A 2XZ1C 1AUMA 1X3OA 3G4SP 2LPKA 2MVVA 2ONTA 4M0IA 2KGEA 2AVAA 3G21A 3G28A 4XFYA 2FADA 4U0BA 3CC4P 3H4EA 4H2WC 4UHPB 2KGCA 7CEIA 2KG9A 2JYGA 2ROQA 3B4QA 1IMQA 4DG9A 3EJDA 1YHQP 3CMEP 1EMVA 2LIUA 2JQ4A 2QEXP 5HGMA 2JB0A 2FACA 2DNWA 1RO2A 2LTEA 4XFXA 2JYLA 3I55P 1M6NA 2L0QA 2GDYA 1E0HA 2FVEA 1VHNA 1D1DA 1S72P 2M8LA 1M74A 2PEMA 4MRTC 3I56P 1VQ9P 2PNGA 3CCSP 2LOLA 3H0DA 2FQ2A 4QKOA 2KGAA 2XV6A 2PEIA 3CCQP 2K5XA 5I4TG 1ZNVA 1L0IA 2K94A 4HKGA 4GR6A 1NJIQ 4XROA 3CMAP 1CEIA 2KR5A 2GZJA 2K0XA 2EHTA 1N8RQ 1UNKA 5F2NA 2EHSA 4IPYA 2FVFA 1QRJA 2GDWA 1YJNP 2CGQA 1BXIA 1IMPA 3CC7P 2GDXA 1RO0A 2PENA 2K2QA 1JJ2O 5CZDB 2KG8A 2MR7A 2PY8A 1IUQA 2FAEA 5KP8B 3MGEA 4NEOA 3DS2A 4PXHB 5HGOA 2CNRA 1E6JP 3EJBA 3CCJP 2VSQA 1BAJA 1M1KQ 2K0DX 4GR2A 2VLPA 2NO8A 2MR8A 4COPA 5BS1A 2XT1A 2LF4A 5HGLA 1VQ7P 2N6ZA 1VQ8P 4XRQA 2XXMA 1M90Q 3DS4A 3G1GA 1QVGO 4PH0A 3CCVP 2K0YA 4WYMA 2AF8A 1YI2P 2OTJP 2OARA 1T8KA 4U0CA 5HGNA 3CCLP 2FQ0A 2JO0A 3U43A 1QVFO 3VRLC 2OTLP 1RNIA 1GPJA 2KWLA 3EJEA 3CC2P 3M1MA 3G29A 2PEJA 1ZMBA 1F80D 4F37A 4U0AA 3G1IA 1VQMP 1Q7YQ 2L9FA 1DV5A 3OW2O 2LMLA 2CWOA 2K93A 3CE7A 1EIAA 1HQBA 4COCA 2MY5A 1Q81Q 2VLNA 2GZFA 5KP7B 1VQLP 1VQNP 5HV8A 2BHVA 4XFZA 2KOSA 1A8OA 4H2XC 1K30A 5F2OA 2XZ0D 3LMOA 2FQ1A 2DGYA 1GXGA 2VLOA 1UJZA 3G71P 2PEKA 3WBHA 2MF4A 5BS2A 1VKUA 2E1MA 4CA3A 1YJWP 1NQ4A 1VQ6P 2MD9A 2EG5A 3E2DA 2N5HA 3CPWO 3G26A 3Q20A 2KGDA 2WPTA 3NY7B 2PEOA 2LIWA 2KORA 2QA4P 2Z44A 2N6YA 2GZGA 2M8NA 2BUOA 1HY8A 2AFEA 2KOQA 1AYIA 2L4BA 2GZEA 2L22A 2LL8A 3G0VA 3CCEP 5EW5E 3GJNA 2EIAA 3RG2A 2JGPA 2KG6A 1K73Q 3CCRP 5JPAA 2P9XA 1VQ5P 2KW2A 1VQOP 2QNWA 1M6EX 2VLQA 3DS1A 2JBGA 2Z46A 3DS3A 2N50A 1VQ4P 3P05A 3H47A 5F2KA 5HVCA 2KOPA 3CXCO 4U0EA 2GYKA 1L0HA 3GKLC 1YITP 1EOQA 2LKIA 1MZ8A 2L6EA 1Q86Q 1KLPA 4U0DA 4H2YC 1YIJP
chains in the Genus database with same CATH topology
2CNRA 2ROQA 3EJBA 2KOOA 2CG5B 1VKUA 4DG9A 3EJDA 2N98A 2VSQA 4CA3A 2LIUA 1NQ4A 4BPHA 2JQ4A 2MR8A 2MD9A 1ACPA 2N5HA 2FACA 2DNWA 2AFDA 2N6ZA 2KGDA 2LTEA 4PWVB 2JU2A 3NY7B 4BPGA 2LIWA 2KORA 4BPFA 2L0QA 2GDYA 2K0YA 2AF8A 2FVEA 2N6YA 5EJDA 1T8KA 1HY8A 3GZLA 4MRTC 2FHSC 2AFEA 2KOQA 2FQ0A 2PNGA 4R0MA 2JU1A 2L4BA 2LOLA 2FQ2A 2L22A 2KGAA 2LL8A 2KWLA 3EJEA 3RG2A 4IZ6A 2JGPA 2CQ8A 2KG6A 2X2BA 1L0IA 2K94A 4HKGA 1F80D 2KR5A 2K0XA 2EHTA 2L9FA 1DNYA 1DV5A 2KW2A 2LMLA 2EHSA 2QNWA 2K93A 5KP6B 3GZMA 2FVAA 3CE7A 2M5RA 2FVFA 2MVUA 2GDWA 2N5IA 1AF8A 1OR5A 1HQBA 2K92A 2XZ1C 2CGQA 2MY5A 1X3OA 2GDXA 2LPKA 2MVVA 2K2QA 2N50A 5KP7B 2KGEA 2AVAA 2KOPA 5HV8A 5HVCA 2KOSA 5CZDB 2KG8A 1L0HA 2MR7A 2FADA 4H2XC 2XZ0D 3LMOA 2FQ1A 4H2WC 2LKIA 1KLPA 4H2YC 2KGCA 2FAEA 5KP8B 2KG9A 4NEOA 4PXHB 2MF4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CNR A;  2ROQ A;  3EJB A;  2KOO A;  2CG5 B;  1VKU A;  4DG9 A;  3EJD A;  2N98 A;  2VSQ A;  4CA3 A;  2LIU A;  1NQ4 A;  4BPH A;  2JQ4 A;  2MR8 A;  2MD9 A;  1ACP A;  2N5H A;  2FAC A;  2DNW A;  2AFD A;  2N6Z A;  2KGD A;  2LTE A;  4PWV B;  2JU2 A;  3NY7 B;  4BPG A;  2LIW A;  2KOR A;  4BPF A;  2L0Q A;  2GDY A;  2K0Y A;  2AF8 A;  2FVE A;  2N6Y A;  5EJD A;  1T8K A;  1HY8 A;  3GZL A;  4MRT C;  2FHS C;  2AFE A;  2KOQ A;  2FQ0 A;  2PNG A;  4R0M A;  2JU1 A;  2L4B A;  2LOL A;  2FQ2 A;  2L22 A;  2KGA A;  2LL8 A;  2KWL A;  3EJE A;  3RG2 A;  4IZ6 A;  2JGP A;  2CQ8 A;  2KG6 A;  2X2B A;  1L0I A;  2K94 A;  4HKG A;  1F80 D;  2KR5 A;  2K0X A;  2EHT A;  2L9F A;  1DNY A;  1DV5 A;  2KW2 A;  2LML A;  2EHS A;  2QNW A;  2K93 A;  5KP6 B;  3GZM A;  2FVA A;  3CE7 A;  2M5R A;  2FVF A;  2MVU A;  2GDW A;  2N5I A;  1AF8 A;  1OR5 A;  1HQB A;  2K92 A;  2XZ1 C;  2CGQ A;  2MY5 A;  1X3O A;  2GDX A;  2LPK A;  2MVV A;  2K2Q A;  2N50 A;  5KP7 B;  2KGE A;  2AVA A;  2KOP A;  5HV8 A;  5HVC A;  2KOS A;  5CZD B;  2KG8 A;  1L0H A;  2MR7 A;  2FAD A;  4H2X C;  2XZ0 D;  3LMO A;  2FQ1 A;  4H2W C;  2LKI A;  1KLP A;  4H2Y C;  2KGC A;  2FAE A;  5KP8 B;  2KG9 A;  4NEO A;  4PXH B;  2MF4 A; 
#chains in the Genus database with same CATH topology
 1A43 A;  2KOO A;  1YJ9 P;  2CG5 B;  1Z6M A;  2N98 A;  4BPH A;  1K9M Q;  2ERH A;  2PEQ A;  3DS5 A;  1ACP A;  1K8A Q;  2AFD A;  1GXH A;  5DCK A;  4PWV B;  3RG6 C;  2JU2 A;  1VQP P;  1Q82 Q;  4BPG A;  4BPF A;  4PH1 A;  3B5I A;  3HZQ A;  5EJD A;  4QNB A;  4U0F A;  1KQS O;  3GZL A;  2FHS C;  3HYB A;  4R0M A;  2JU1 A;  3DTJ A;  2Z45 A;  2JAZ A;  2KOD A;  2EFJ A;  3NTE A;  4IZ6 A;  1VQK P;  2CQ8 A;  3DS0 A;  3LRY A;  2GZI A;  2X2B A;  3DPH A;  1FR2 A;  1KD1 Q;  3CCU P;  3G6E P;  2M8P A;  1DNY A;  1KC8 Q;  3CCM P;  3CD6 P;  5KP6 B;  3GZM A;  2FVA A;  2M5R A;  2MVU A;  1W2B O;  2N5I A;  1AF8 A;  1OR5 A;  2K92 A;  2XZ1 C;  1AUM A;  1X3O A;  3G4S P;  2LPK A;  2MVV A;  2ONT A;  4M0I A;  2KGE A;  2AVA A;  3G21 A;  3G28 A;  4XFY A;  2FAD A;  4U0B A;  3CC4 P;  3H4E A;  4H2W C;  4UHP B;  2KGC A;  7CEI A;  2KG9 A;  2JYG A;  2ROQ A;  3B4Q A;  1IMQ A;  4DG9 A;  3EJD A;  1YHQ P;  3CME P;  1EMV A;  2LIU A;  2JQ4 A;  2QEX P;  5HGM A;  2JB0 A;  2FAC A;  2DNW A;  1RO2 A;  2LTE A;  4XFX A;  2JYL A;  3I55 P;  1M6N A;  2L0Q A;  2GDY A;  1E0H A;  2FVE A;  1VHN A;  1D1D A;  1S72 P;  2M8L A;  1M74 A;  2PEM A;  4MRT C;  3I56 P;  1VQ9 P;  2PNG A;  3CCS P;  2LOL A;  3H0D A;  2FQ2 A;  4QKO A;  2KGA A;  2XV6 A;  2PEI A;  3CCQ P;  2K5X A;  5I4T G;  1ZNV A;  1L0I A;  2K94 A;  4HKG A;  4GR6 A;  1NJI Q;  4XRO A;  3CMA P;  1CEI A;  2KR5 A;  2GZJ A;  2K0X A;  2EHT A;  1N8R Q;  1UNK A;  5F2N A;  2EHS A;  4IPY A;  2FVF A;  1QRJ A;  2GDW A;  1YJN P;  2CGQ A;  1BXI A;  1IMP A;  3CC7 P;  2GDX A;  1RO0 A;  2PEN A;  2K2Q A;  1JJ2 O;  5CZD B;  2KG8 A;  2MR7 A;  2PY8 A;  1IUQ A;  2FAE A;  5KP8 B;  3MGE A;  4NEO A;  3DS2 A;  4PXH B;  5HGO A;  2CNR A;  1E6J P;  3EJB A;  3CCJ P;  2VSQ A;  1BAJ A;  1M1K Q;  2K0D X;  4GR2 A;  2VLP A;  2NO8 A;  2MR8 A;  4COP A;  5BS1 A;  2XT1 A;  2LF4 A;  5HGL A;  1VQ7 P;  2N6Z A;  1VQ8 P;  4XRQ A;  2XXM A;  1M90 Q;  3DS4 A;  3G1G A;  1QVG O;  4PH0 A;  3CCV P;  2K0Y A;  4WYM A;  2AF8 A;  1YI2 P;  2OTJ P;  2OAR A;  1T8K A;  4U0C A;  5HGN A;  3CCL P;  2FQ0 A;  2JO0 A;  3U43 A;  1QVF O;  3VRL C;  2OTL P;  1RNI A;  1GPJ A;  2KWL A;  3EJE A;  3CC2 P;  3M1M A;  3G29 A;  2PEJ A;  1ZMB A;  1F80 D;  4F37 A;  4U0A A;  3G1I A;  1VQM P;  1Q7Y Q;  2L9F A;  1DV5 A;  3OW2 O;  2LML A;  2CWO A;  2K93 A;  3CE7 A;  1EIA A;  1HQB A;  4COC A;  2MY5 A;  1Q81 Q;  2VLN A;  2GZF A;  5KP7 B;  1VQL P;  1VQN P;  5HV8 A;  2BHV A;  4XFZ A;  2KOS A;  1A8O A;  4H2X C;  1K30 A;  5F2O A;  2XZ0 D;  3LMO A;  2FQ1 A;  2DGY A;  1GXG A;  2VLO A;  1UJZ A;  3G71 P;  2PEK A;  3WBH A;  2MF4 A;  5BS2 A;  1VKU A;  2E1M A;  4CA3 A;  1YJW P;  1NQ4 A;  1VQ6 P;  2MD9 A;  2EG5 A;  3E2D A;  2N5H A;  3CPW O;  3G26 A;  3Q20 A;  2KGD A;  2WPT A;  3NY7 B;  2PEO A;  2LIW A;  2KOR A;  2QA4 P;  2Z44 A;  2N6Y A;  2GZG A;  2M8N A;  2BUO A;  1HY8 A;  2AFE A;  2KOQ A;  1AYI A;  2L4B A;  2GZE A;  2L22 A;  2LL8 A;  3G0V A;  3CCE P;  5EW5 E;  3GJN A;  2EIA A;  3RG2 A;  2JGP A;  2KG6 A;  1K73 Q;  3CCR P;  5JPA A;  2P9X A;  1VQ5 P;  2KW2 A;  1VQO P;  2QNW A;  1M6E X;  2VLQ A;  3DS1 A;  2JBG A;  2Z46 A;  3DS3 A;  2N50 A;  1VQ4 P;  3P05 A;  3H47 A;  5F2K A;  5HVC A;  2KOP A;  3CXC O;  4U0E A;  2GYK A;  1L0H A;  3GKL C;  1YIT P;  1EOQ A;  2LKI A;  1MZ8 A;  2L6E A;  1Q86 Q;  1KLP A;  4U0D A;  4H2Y C;  1YIJ P; 
#chains in the Genus database with same CATH homology
 2CNR A;  2ROQ A;  3EJB A;  2KOO A;  2CG5 B;  1VKU A;  4DG9 A;  3EJD A;  2N98 A;  2VSQ A;  4CA3 A;  2LIU A;  1NQ4 A;  4BPH A;  2JQ4 A;  2MR8 A;  2MD9 A;  1ACP A;  2N5H A;  2FAC A;  2DNW A;  2AFD A;  2N6Z A;  2KGD A;  2LTE A;  4PWV B;  2JU2 A;  3NY7 B;  4BPG A;  2LIW A;  2KOR A;  4BPF A;  2L0Q A;  2GDY A;  2K0Y A;  2AF8 A;  2FVE A;  2N6Y A;  5EJD A;  1T8K A;  1HY8 A;  3GZL A;  4MRT C;  2FHS C;  2AFE A;  2KOQ A;  2FQ0 A;  2PNG A;  4R0M A;  2JU1 A;  2L4B A;  2LOL A;  2FQ2 A;  2L22 A;  2KGA A;  2LL8 A;  2KWL A;  3EJE A;  3RG2 A;  4IZ6 A;  2JGP A;  2CQ8 A;  2KG6 A;  2X2B A;  1L0I A;  2K94 A;  4HKG A;  1F80 D;  2KR5 A;  2K0X A;  2EHT A;  2L9F A;  1DNY A;  1DV5 A;  2KW2 A;  2LML A;  2EHS A;  2QNW A;  2K93 A;  5KP6 B;  3GZM A;  2FVA A;  3CE7 A;  2M5R A;  2FVF A;  2MVU A;  2GDW A;  2N5I A;  1AF8 A;  1OR5 A;  1HQB A;  2K92 A;  2XZ1 C;  2CGQ A;  2MY5 A;  1X3O A;  2GDX A;  2LPK A;  2MVV A;  2K2Q A;  2N50 A;  5KP7 B;  2KGE A;  2AVA A;  2KOP A;  5HV8 A;  5HVC A;  2KOS A;  5CZD B;  2KG8 A;  1L0H A;  2MR7 A;  2FAD A;  4H2X C;  2XZ0 D;  3LMO A;  2FQ1 A;  4H2W C;  2LKI A;  1KLP A;  4H2Y C;  2KGC A;  2FAE A;  5KP8 B;  2KG9 A;  4NEO A;  4PXH B;  2MF4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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