2KIGA

A ph domain within ocrl bridges clathrin mediated membrane trafficking to phosphoinositide metabolism
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
161
structure length
161
Chain Sequence
GPLGSMDQSVAIQETLVEGEYCVIAVQGVLCKGDSRQSRLLGLVRYRLENDAQEHALFLYTHRRMAITGDDVSLDQIVPLSKDFMLEEVSPDGELYILGSDVTVQLNTAELKLVFQLPFGSHTRTFLQEVARACPGFDPETRDPEFEWLSRHTCAEPDAES
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A PH domain within OCRL bridges clathrin-mediated membrane trafficking to phosphoinositide metabolism.
pubmed doi rcsb
molecule tags Endocytosis, hydrolase
source organism Mus musculus
molecule keywords Inositol polyphosphate 5-phosphatase II isoform
total genus 16
structure length 161
sequence length 161
ec nomenclature ec 3.1.3.36: Phosphoinositide 5-phosphatase.
pdb deposition date 2009-05-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF16776 INPP5B_PH Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.110 Mainly Beta Roll PH-domain like PH-domain like 2kigA00
2KIGA 2KIEA
chains in the Genus database with same CATH superfamily
3PVWA 3U7DA 2Z0QA 1U29A 2ELAA 3CXBB 5I2SA 2K49A 3HK0A 1MIZB 2KCJA 5C16A 2R0DA 4QXAB 1TQZA 1UNQA 2UZSA 3NWDA 3DXDA 1N3HA 2I1KA 2XQNM 1U2BA 3M1IB 5JHGA 1XKEA 2D4QA 2EMSA 4WVFB 2D11A 2MKRA 1XCGA 4CYEA 3T06A 4A6FA 4HSIA 2H7EA 1NTVA 2YT0A 4K2PA 4BBKA 1MKEA 2ELBA 4Y94A 3ML4A 3PVUA 4MT7A 2QKMA 2IFSA 2J0JA 2M14A 2YVCA 4K81A 5J3TA 4K2OA 2COFA 1MAIA 1ZC3B 3MDBC 3ODOA 2I5FA 5LOPB 4IAPA 2LYDA 4GPTB 4K17A 5JHHA 2P8VA 2KUPA 4IFSA 4DBBA 1BAKA 3ZDTA 1M7EA 5GOWB 4KHBB 1GG3A 3ULCA 4YL8A 2GJYA 5HE1A 5LONB 1ISNA 4A5KA 1NU2A 2KIEA 1B55A 4D0NB 4ZRKA 4ZRIA 4GMVA 2D9YA 2DHIA 4QJ4B 5I2MA 5KQ4A 1Z87A 1KZ7A 4KAXB 3KRWA 4IOYX 3A8PA 3D8EA 5C5BB 2VSZA 3SYXA 1I2HA 1U5EA 1WJMA 2P0FA 3FVCA 4GOUA 1I7AA 2UZRA 2LOXA 2ROVA 3WYFB 4GN1A 2J59M 2Q13A 3PSCA 3AU4A 1FGZA 3NSUA 4D6WA 2D9ZA 2CRFA 3RCPA 1PLSA 3PP2A 4HAZB 2Y8FA 2K2JA 4HB2B 2FJUB 4HHVA 5C5BA 2Y7BA 4B6HA 1K5DB 4DX90 4HAWB 1X11A 1V5UA 2NMBA 1DDWA 1P6SA 3OHMB 2DTCA 1U27A 5L81A 1XODA 3OANA 4DXAB 1XR0B 2J0MA 1UNRA 4EKUA 3P7ZA 1FHWA 2CODA 4GNKB 1H10A 5J3YA 3F5RA 2EC1A 1J19A 3DXEA 4A6FB 2ZKMX 4WJ7A 1W1GA 2YT1A 2N23A 1WG7A 2L1CA 5D3WA 2P0HA 5CLLB 5J3QA 1ZC4B 1RJ2A 1WVHA 5HE0A 2NBVA 1OQNA 4CSQA 4HATB 5EFXA 2DLWA 1W1DA 1WI1A 4L1RA 2YT2A 3BINA 1MK7B 4EMOA 3HSAA 4F7UP 1LW3A 5D3YA 1GC6A 2LULA 2DYNA 4DX8A 3ULBA 2LKOA 2RGNB 2GCJA 5D3XA 2P0DA 5HE2A 1TXDA 2Z13A 4CHMA 1BTNA 2MDXA 1Y19B 4MY6A 3TFMA 2D9XA 3KRXA 2VRWB 3LJUX 2YF0A 3FM8C 4GMXB 1GC7A 2OTXA 3D8DA 2HTHB 3P6AA 1H4RA 1U5GA 1V89A 2IYBA 4DIXA 2CY5A 1QC6A 1DBHA 3HIEA 2YS1A 3KZ1A 1OMWA 1X05A 1Y5OA 2ZPYA 2DA0A 2EJ8A 3A58A 4P7IA 3X23A 1DYNA 1MPHA 1FB8A 3KY9A 1K5GB 1FOEA 2GS0A 1WGUA 1P5TA 1V5MA 2KGXB 4HB0B 3G9WA 2AEHA 4CHJA 1BWNA 2PZ1A 2DKQA 3TO1A 5LG4B 1AWEA 4L6EA 2D9VA 1UNPA 4A6HA 3O96A 1NI2A 1DDVA 1PFJA 2DX1A 2RRFA 2N0YA 2DHJA 5DHAB 4GXBA 1W1HA 3PZDA 3QIJA 2KIGA 3QWMA 2DYQA 4KHAA 2COAA 2K8EA 1FAOA 2RUKB 1KZGA 2DHKA 4F7HA 2RVBB 1SGHA 5JLJB 2QKLA 2YS5A 3CIKA 4Z2NA 2ROZB 3FEHA 2GUMA 2R2YA 2FJLA 3SUZA 1X1GA 1AQCA 2OQBA 1Q67A 1DDMA 1FGYA 3A8QA 1EF1A 4KVGB 4HAYB 3MPXA 4HAVB 1J0WA 2Z59A 5CLQB 2RNRB 3PG7A 2EMTA 2CAYA 3SV1A 4KHOA 4TYZA 4QJ5B 4EJNA 2ADZA 2COCA 2MFQA 2GCLA 2G35A 2RLOA 4F7GA 1RRPB 1XX0A 3AU5A 2L2IA 2YRYA 3IVFA 1FHXA 2DFKA 1ZSQA 1BTKA 3GYOA 2Y8GA 2CY4A 1WJ1A 3GYPA 3U8ZA 1LB1A 2LG1A 2RSGA 4MK0A 1XD4A 2JP2A 5D3VA 1V61A 5M4YB 2W2XD 3NWAA 5FI0A 3NWFA 2W2XC 2DX5A 2DN6A 3TCAA 1TJ6A 4XWXA 1M7RA 1ZYIA 3FSSA 4GZUA 2J0KA 1NTYA 2VKIA 1PMSA 3ZVRA 4PQ0A 4TKNA 3A98B 3WA0A 3DCXA 2K00A 3F0WA 4HB3B 4C0AA 1P3RA 4HDOA 2DKPA 3DXCA 2YS3A 2AL6A 4HAXB 3HQCA 4OT1A 5DIFB 1FHOA 4HDQA 2K2UA 3D8FA 5HE3A 3V5WA 5C6RA 1EVHA 4HB4B 2H7DA 5FI1A 2KR0A 1EAZA 1X1FA 2UVMA 1IRSA 3SO6A 1MIXA 5DI9B 3HW2B 3KSYA 2I5CA 3N7CA 1E5WA 1V5PA 1WGQA 1SHCA 1U5DA 1ZM0A 4PNKA 1QQGA 1UEFA 2Z4DA 3PEGA 2E2XA 5C79A 4Z2MB 1UPRA 2HE7A 2MWNB 3U12A 2I1JA 3B77A 1OY2A 2YSZA 4WSFA 3PVLA 3NW8A 5D27A 5KCVA 4OSNA 3VIAA 2BCJA 4KHBA 1EGXA 5KQ1A 3VOQA 4NY0A 2V76A 2D9WA 4H8SA 4NSWA 1U5FA 4A6KA 2Z0OA 3SNHA 1DROA 4ZRJA 1T77A 1UPQA 2X18A 1MK9B 2R09A 4YONA 2Z0PA 3BJIA 4QJ3B 2D10A 2W2WA 5DHFB 2KUQA 1MI1A 2D2QA 3QBVB 2LOZA 1ZVRA 3TW1A 3UZTA 3ODXA 4HAUB 5JP4A 2M38A 2NZ8B 3TVVA 3AJ4A 1X86A 1V88A 3ODWA 1KI1B 5IRSA 2Z14A 5DH9B
chains in the Genus database with same CATH topology
5I2MA 3U12A 2GCJA 2NBVA 4Z2MB 4QJ3B 3A58A 4CSQA 4GNKB 1ZYIA 2KUQA 2FJUB 3FSSA 4IOYX 2RRFA 2KR0A 4L1RA 4PQ0A 2Z13A 3NW8A 2YT2A 4OT1A 3TW1A 2Z59A 2K49A 2KIGA 3GYOA 3FVCA 4IFSA 4KHAA 5I2SA 4HSIA 2K8EA 4GOUA 4OSNA 4KHBA 2ZKMX 3GYPA 4KHOA 4KHBB 4QJ5B 2KIEA 3TVVA 5M4YB 3OHMB 4QXAB 2Z4DA 3NWAA 3NWDA 3NWFA 4DIXA 4Z2NA 2GCLA 3TO1A 2Z14A 2GUMA 2R2YA 5LG4B 5IRSA 4QJ4B 4D6WA 3HIEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KIG A;  2KIE A; 
#chains in the Genus database with same CATH topology
 3PVW A;  3U7D A;  2Z0Q A;  1U29 A;  2ELA A;  3CXB B;  5I2S A;  2K49 A;  3HK0 A;  1MIZ B;  2KCJ A;  5C16 A;  2R0D A;  4QXA B;  1TQZ A;  1UNQ A;  2UZS A;  3NWD A;  3DXD A;  1N3H A;  2I1K A;  2XQN M;  1U2B A;  3M1I B;  5JHG A;  1XKE A;  2D4Q A;  2EMS A;  4WVF B;  2D11 A;  2MKR A;  1XCG A;  4CYE A;  3T06 A;  4A6F A;  4HSI A;  2H7E A;  1NTV A;  2YT0 A;  4K2P A;  4BBK A;  1MKE A;  2ELB A;  4Y94 A;  3ML4 A;  3PVU A;  4MT7 A;  2QKM A;  2IFS A;  2J0J A;  2M14 A;  2YVC A;  4K81 A;  5J3T A;  4K2O A;  2COF A;  1MAI A;  1ZC3 B;  3MDB C;  3ODO A;  2I5F A;  5LOP B;  4IAP A;  2LYD A;  4GPT B;  4K17 A;  5JHH A;  2P8V A;  2KUP A;  4IFS A;  4DBB A;  1BAK A;  3ZDT A;  1M7E A;  5GOW B;  4KHB B;  1GG3 A;  3ULC A;  4YL8 A;  2GJY A;  5HE1 A;  5LON B;  1ISN A;  4A5K A;  1NU2 A;  2KIE A;  1B55 A;  4D0N B;  4ZRK A;  4ZRI A;  4GMV A;  2D9Y A;  2DHI A;  4QJ4 B;  5I2M A;  5KQ4 A;  1Z87 A;  1KZ7 A;  4KAX B;  3KRW A;  4IOY X;  3A8P A;  3D8E A;  5C5B B;  2VSZ A;  3SYX A;  1I2H A;  1U5E A;  1WJM A;  2P0F A;  3FVC A;  4GOU A;  1I7A A;  2UZR A;  2LOX A;  2ROV A;  3WYF B;  4GN1 A;  2J59 M;  2Q13 A;  3PSC A;  3AU4 A;  1FGZ A;  3NSU A;  4D6W A;  2D9Z A;  2CRF A;  3RCP A;  1PLS A;  3PP2 A;  4HAZ B;  2Y8F A;  2K2J A;  4HB2 B;  2FJU B;  4HHV A;  5C5B A;  2Y7B A;  4B6H A;  1K5D B;  4DX9 0;  4HAW B;  1X11 A;  1V5U A;  2NMB A;  1DDW A;  1P6S A;  3OHM B;  2DTC A;  1U27 A;  5L81 A;  1XOD A;  3OAN A;  4DXA B;  1XR0 B;  2J0M A;  1UNR A;  4EKU A;  3P7Z A;  1FHW A;  2COD A;  4GNK B;  1H10 A;  5J3Y A;  3F5R A;  2EC1 A;  1J19 A;  3DXE A;  4A6F B;  2ZKM X;  4WJ7 A;  1W1G A;  2YT1 A;  2N23 A;  1WG7 A;  2L1C A;  5D3W A;  2P0H A;  5CLL B;  5J3Q A;  1ZC4 B;  1RJ2 A;  1WVH A;  5HE0 A;  2NBV A;  1OQN A;  4CSQ A;  4HAT B;  5EFX A;  2DLW A;  1W1D A;  1WI1 A;  4L1R A;  2YT2 A;  3BIN A;  1MK7 B;  4EMO A;  3HSA A;  4F7U P;  1LW3 A;  5D3Y A;  1GC6 A;  2LUL A;  2DYN A;  4DX8 A;  3ULB A;  2LKO A;  2RGN B;  2GCJ A;  5D3X A;  2P0D A;  5HE2 A;  1TXD A;  2Z13 A;  4CHM A;  1BTN A;  2MDX A;  1Y19 B;  4MY6 A;  3TFM A;  2D9X A;  3KRX A;  2VRW B;  3LJU X;  2YF0 A;  3FM8 C;  4GMX B;  1GC7 A;  2OTX A;  3D8D A;  2HTH B;  3P6A A;  1H4R A;  1U5G A;  1V89 A;  2IYB A;  4DIX A;  2CY5 A;  1QC6 A;  1DBH A;  3HIE A;  2YS1 A;  3KZ1 A;  1OMW A;  1X05 A;  1Y5O A;  2ZPY A;  2DA0 A;  2EJ8 A;  3A58 A;  4P7I A;  3X23 A;  1DYN A;  1MPH A;  1FB8 A;  3KY9 A;  1K5G B;  1FOE A;  2GS0 A;  1WGU A;  1P5T A;  1V5M A;  2KGX B;  4HB0 B;  3G9W A;  2AEH A;  4CHJ A;  1BWN A;  2PZ1 A;  2DKQ A;  3TO1 A;  5LG4 B;  1AWE A;  4L6E A;  2D9V A;  1UNP A;  4A6H A;  3O96 A;  1NI2 A;  1DDV A;  1PFJ A;  2DX1 A;  2RRF A;  2N0Y A;  2DHJ A;  5DHA B;  4GXB A;  1W1H A;  3PZD A;  3QIJ A;  2KIG A;  3QWM A;  2DYQ A;  4KHA A;  2COA A;  2K8E A;  1FAO A;  2RUK B;  1KZG A;  2DHK A;  4F7H A;  2RVB B;  1SGH A;  5JLJ B;  2QKL A;  2YS5 A;  3CIK A;  4Z2N A;  2ROZ B;  3FEH A;  2GUM A;  2R2Y A;  2FJL A;  3SUZ A;  1X1G A;  1AQC A;  2OQB A;  1Q67 A;  1DDM A;  1FGY A;  3A8Q A;  1EF1 A;  4KVG B;  4HAY B;  3MPX A;  4HAV B;  1J0W A;  2Z59 A;  5CLQ B;  2RNR B;  3PG7 A;  2EMT A;  2CAY A;  3SV1 A;  4KHO A;  4TYZ A;  4QJ5 B;  4EJN A;  2ADZ A;  2COC A;  2MFQ A;  2GCL A;  2G35 A;  2RLO A;  4F7G A;  1RRP B;  1XX0 A;  3AU5 A;  2L2I A;  2YRY A;  3IVF A;  1FHX A;  2DFK A;  1ZSQ A;  1BTK A;  3GYO A;  2Y8G A;  2CY4 A;  1WJ1 A;  3GYP A;  3U8Z A;  1LB1 A;  2LG1 A;  2RSG A;  4MK0 A;  1XD4 A;  2JP2 A;  5D3V A;  1V61 A;  5M4Y B;  2W2X D;  3NWA A;  5FI0 A;  3NWF A;  2W2X C;  2DX5 A;  2DN6 A;  3TCA A;  1TJ6 A;  4XWX A;  1M7R A;  1ZYI A;  3FSS A;  4GZU A;  2J0K A;  1NTY A;  2VKI A;  1PMS A;  3ZVR A;  4PQ0 A;  4TKN A;  3A98 B;  3WA0 A;  3DCX A;  2K00 A;  3F0W A;  4HB3 B;  4C0A A;  1P3R A;  4HDO A;  2DKP A;  3DXC A;  2YS3 A;  2AL6 A;  4HAX B;  3HQC A;  4OT1 A;  5DIF B;  1FHO A;  4HDQ A;  2K2U A;  3D8F A;  5HE3 A;  3V5W A;  5C6R A;  1EVH A;  4HB4 B;  2H7D A;  5FI1 A;  2KR0 A;  1EAZ A;  1X1F A;  2UVM A;  1IRS A;  3SO6 A;  1MIX A;  5DI9 B;  3HW2 B;  3KSY A;  2I5C A;  3N7C A;  1E5W A;  1V5P A;  1WGQ A;  1SHC A;  1U5D A;  1ZM0 A;  4PNK A;  1QQG A;  1UEF A;  2Z4D A;  3PEG A;  2E2X A;  5C79 A;  4Z2M B;  1UPR A;  2HE7 A;  2MWN B;  3U12 A;  2I1J A;  3B77 A;  1OY2 A;  2YSZ A;  4WSF A;  3PVL A;  3NW8 A;  5D27 A;  5KCV A;  4OSN A;  3VIA A;  2BCJ A;  4KHB A;  1EGX A;  5KQ1 A;  3VOQ A;  4NY0 A;  2V76 A;  2D9W A;  4H8S A;  4NSW A;  1U5F A;  4A6K A;  2Z0O A;  3SNH A;  1DRO A;  4ZRJ A;  1T77 A;  1UPQ A;  2X18 A;  1MK9 B;  2R09 A;  4YON A;  2Z0P A;  3BJI A;  4QJ3 B;  2D10 A;  2W2W A;  5DHF B;  2KUQ A;  1MI1 A;  2D2Q A;  3QBV B;  2LOZ A;  1ZVR A;  3TW1 A;  3UZT A;  3ODX A;  4HAU B;  5JP4 A;  2M38 A;  2NZ8 B;  3TVV A;  3AJ4 A;  1X86 A;  1V88 A;  3ODW A;  1KI1 B;  5IRS A;  2Z14 A;  5DH9 B; 
#chains in the Genus database with same CATH homology
 5I2M A;  3U12 A;  2GCJ A;  2NBV A;  4Z2M B;  4QJ3 B;  3A58 A;  4CSQ A;  4GNK B;  1ZYI A;  2KUQ A;  2FJU B;  3FSS A;  4IOY X;  2RRF A;  2KR0 A;  4L1R A;  4PQ0 A;  2Z13 A;  3NW8 A;  2YT2 A;  4OT1 A;  3TW1 A;  2Z59 A;  2K49 A;  2KIG A;  3GYO A;  3FVC A;  4IFS A;  4KHA A;  5I2S A;  4HSI A;  2K8E A;  4GOU A;  4OSN A;  4KHB A;  2ZKM X;  3GYP A;  4KHO A;  4KHB B;  4QJ5 B;  2KIE A;  3TVV A;  5M4Y B;  3OHM B;  4QXA B;  2Z4D A;  3NWA A;  3NWD A;  3NWF A;  4DIX A;  4Z2N A;  2GCL A;  3TO1 A;  2Z14 A;  2GUM A;  2R2Y A;  5LG4 B;  5IRS A;  4QJ4 B;  4D6W A;  3HIE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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