2KJIA

A divergent ins protein in c. elegans structurally resemble insulin and activates the human insulin receptor
Total Genus 9
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
9
sequence length
50
structure length
50
Chain Sequence
GETRACGRKLISLVMAVCGDLCNPQEGKDIATECCGNQCSDDYIRSACCP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hormone
molecule keywords Probable insulin-like peptide beta-type 5
publication title Insulin worms its way into the spotlight.
pubmed doi rcsb
source organism Caenorhabditis elegans
total genus 9
structure length 50
sequence length 50
ec nomenclature
pdb deposition date 2009-05-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03488 Ins_beta Nematode insulin-related peptide beta type
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 2kjiA00
1GZRB 2L29B 1IMXA 1GZZB 1H02B 1WQJI 1EFEA 2DSPI 1TGRA 3KR3D 5L3LA 4XSSB 1H59A 2DSRI 1BQTA 1SJUA 2GF1A 2JZQA 3LRIA 1PMXA 1ZEIA 6INSE 1GZYB 5L3NA 5L3MA 1B9GA 2DSQC 2KJIA 2KQPA 2LWZA 3GF1A 1IGLA
chains in the Genus database with same CATH superfamily
1GZRB 2L29B 1IMXA 1GZZB 1H02B 1WQJI 1EFEA 2DSPI 1TGRA 3KR3D 3F2DA 5L3LA 4XSSB 3F2CA 1H59A 2DSRI 1BQTA 1SJUA 2GF1A 2JZQA 3LRIA 2L14B 1PMXA 1ZEIA 6INSE 1GZYB 5L3NA 5L3MA 1B9GA 2DSQC 2KJIA 3F2BA 2KQPA 2LWZA 3GF1A 1IGLA
chains in the Genus database with same CATH topology
1GZRB 2L29B 1IMXA 1GZZB 1H02B 1WQJI 1EFEA 2DSPI 1TGRA 3KR3D 5L3LA 4XSSB 1H59A 2DSRI 1BQTA 1SJUA 2GF1A 2JZQA 3LRIA 1PMXA 1ZEIA 6INSE 1GZYB 5L3NA 5L3MA 1B9GA 2DSQC 2KJIA 2KQPA 2LWZA 3GF1A 1IGLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GZR B;  2L29 B;  1IMX A;  1GZZ B;  1H02 B;  1WQJ I;  1EFE A;  2DSP I;  1TGR A;  3KR3 D;  5L3L A;  4XSS B;  1H59 A;  2DSR I;  1BQT A;  1SJU A;  2GF1 A;  2JZQ A;  3LRI A;  1PMX A;  1ZEI A;  6INS E;  1GZY B;  5L3N A;  5L3M A;  1B9G A;  2DSQ C;  2KJI A;  2KQP A;  2LWZ A;  3GF1 A;  1IGL A; 
#chains in the Genus database with same CATH topology
 1GZR B;  2L29 B;  1IMX A;  1GZZ B;  1H02 B;  1WQJ I;  1EFE A;  2DSP I;  1TGR A;  3KR3 D;  3F2D A;  5L3L A;  4XSS B;  3F2C A;  1H59 A;  2DSR I;  1BQT A;  1SJU A;  2GF1 A;  2JZQ A;  3LRI A;  2L14 B;  1PMX A;  1ZEI A;  6INS E;  1GZY B;  5L3N A;  5L3M A;  1B9G A;  2DSQ C;  2KJI A;  3F2B A;  2KQP A;  2LWZ A;  3GF1 A;  1IGL A; 
#chains in the Genus database with same CATH homology
 1GZR B;  2L29 B;  1IMX A;  1GZZ B;  1H02 B;  1WQJ I;  1EFE A;  2DSP I;  1TGR A;  3KR3 D;  5L3L A;  4XSS B;  1H59 A;  2DSR I;  1BQT A;  1SJU A;  2GF1 A;  2JZQ A;  3LRI A;  1PMX A;  1ZEI A;  6INS E;  1GZY B;  5L3N A;  5L3M A;  1B9G A;  2DSQ C;  2KJI A;  2KQP A;  2LWZ A;  3GF1 A;  1IGL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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