2KMRA

Solution structure of intermediate iic of leech-derived tryptase inhibitor, ldti.
Total Genus 4
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
4
sequence length
44
structure length
44
Chain Sequence
KKVCACPKILKPVCGSDGRTYANSCIARCNGVSIKSEGSCPTGI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
pubmed doi rcsb
molecule tags Hydrolase
source organism Hirudo medicinalis
molecule keywords Leech-derived tryptase inhibitor C
total genus 4
structure length 44
sequence length 44
ec nomenclature
pdb deposition date 2009-08-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 2kmrA01
1Y1CA 1CT2I 2BUSA 2JZMA 2NU2I 2QQCA 1R0RI 2GKVA 5DAEA 2KCXA 3B4VC 1CSOI 1Z7KB 1Y1BA 2KMPA 1IW4A 1H0ZA 1CHOI 2SGPI 4HGUA 1TGSI 1IY5A 2SGEI 1CGJI 1CT4I 1DS3I 2JYYA 2NU4I 1OMTA 1UUCA 1BMOA 1TBQR 1AN1I 2P6AC 2SGQI 2N52A 1MT1A 1M8BA 1CT0I 1TUSA 1PPFI 1OMUA 3OVOA 2KMOA 2NU3I 2JXDA 1SGYI 1OVOA 1CE3A 1CGII 1LR8A 1M8CA 3SGBI 1SGRI 1HPTA 2GKRI 1PCEA 1HJAI 2NU0I 1NUBA 1SGDI 2V53A 4OVOA 2N17A 1N13A 3SEKC 2WCYA 1YTPA 4SGBI 1TURA 2B0UC 3SGQI 1SGPI 2F3CI 2OVOA 1SGQI 2N71A 1YU6C 2SGDI 1SGEI 2LEOA 3TJQA 1DS2I 1TBRR 1FYBA 2ARPF 5JHWC 1PJUA 2NU1I 2M5XA 1UVGA 1SGNI 1HDLA 1LR7A 1TIHA 2ERWA 3QTLD 1IY6A 1UVFA 2QQDA 2KMQA 2XRCA 1LR9A 1BUSA 3HH2C 1KMAA 2SGFI 1OYVI 2KMRA 4GI3C 2GKTI
chains in the Genus database with same CATH superfamily
2K9HA 3D00A 2WVJA 1Y1CA 1CT2I 1NXUA 1U5KA 1TBNA 2ORWA 2BUSA 3RU0A 3VDUA 1FY7A 1R79A 4UXJA 2JZMA 2A20A 2NU2I 2L8EA 2OD1A 4UXHA 1WGCA 2QQCA 1R0RI 2GKVA 5DAEA 5CCLA 2ENZA 5HQ8A 1WKXA 2KCXA 2X3TA 4MPIA 4UXIA 7WGAA 3B4VC 3UEYA 1CSOI 2CWFA 1Z7KB 1Y1BA 3UEJA 5FUWA 1TBOA 2E5RA 1ULMA 3BJIA 2YUUA 1Y8FA 2KMPA 3R5DA 3R5BA 1XBTA 2ORVA 1IW4A 1H0ZA 3UGLA 1S20A 2QPOA 3QAHA 1CHOI 2SGPI 2LB7A 4HGUA 1TGSI 1ULNA 1IY5A 2SGEI 1CGJI 3E59A 5HI7A 1CT4I 1Q9BA 1TOTA 2B8TA 1DS3I 2J9RA 3OXLA 5FUYA 2JYYA 2NU4I 1OMTA 2ELIA 5E3PA 1WTJA 1P9GA 2QQ0A 1W4RA 1UUCA 1BMOA 1MJ9A 1AN1I 1TBQR 2P6AC 3UGIA 3UOEA 2SGQI 4B6DA 1FARA 1WGTA 5J8CA 2N52A 1MT1A 1M8BA 1UHAA 2GIVA 3UFFA 1CT0I 2N1AB 2W0TA 1KBFA 1TUSA 1PPFI 1OMUA 3OVOA 3R5AA 5EX0A 2ENNA 2FNFX 2V1CC 2ODDA 2KMOA 1V1HA 2NU3I 1PTRA 1XX6A 2JXDA 1SGYI 2VRWB 3TO7A 1OVOA 1CE3A 1CGII 1LR8A 5J8FA 1M8CA 3SGBI 1SGRI 1V1IA 1HPTA 2GKRI 1PTQA 1PCEA 9WGAA 2UVOA 3FC3A 1HJAI 1K7VA 1FAQA 1K7TA 2WGCA 2DB6A 5EX3A 2NU0I 2CWHA 5FUXA 1NUBA 1SGDI 2V53A 3TOBA 4OVOA 2N17A 2ROWA 1N13A 3TO9A 3SEKC 2WCYA 2UZ3A 1YTPA 4SGBI 1TURA 2B0UC 3UGDA 3SGQI 1P9ZA 1SGPI 2F3CI 4DNCA 5CCMA 3GOXA 2X52A 2OVOA 1SGQI 2N71A 1YU6C 5E3RA 2JA1A 2SGDI 4L9MA 2L7XA 4JCVE 3CXLA 1SGEI 2LEOA 3TJQA 3VE5A 2OZUA 1DS2I 2RIJA 3MEKA 1W3SA 2DKVA 3QWPA 4E1RA 4AMLA 1MJAA 2V1CA 2CWGA 3TO6A 2OU2A 3R5CA 1RFHA 3TOAA 1TBRR 1FYBA 5E3QA 2ARPF 2CJSC 3VDPA 5JHWC 1PJUA 2NU1I 3E2IA 4A24A 1K7UA 2RC4A 1Z2IA 2M5XA 1UVGA 4E1PA 1SGNI 3OXFA 1LR7A 2PQ8A 1HDLA 1TIHA 2ERWA 1HEVA 3QTLD 1MJBA 1IY6A 5FUVA 1UVFA 2YQPA 2QQDA 1KBEA 2DIPA 2KMQA 1LR9A 1X74A 2XRCA 3OL0A 4WP4A 1XA6A 4FKDA 1X4SA 3HH2C 1BUSA 1VDDA 2J87A 2JW6A 1KMAA 2LUYA 2SGFI 1OYVI 3OXGA 3PDNA 2E73A 3FSXA 2KMRA 1ULKA 2GVIA 2Y0MA 2GKTI 4GI3C 3KY9A 3FSYA 2QQEA
chains in the Genus database with same CATH topology
2K9HA 3D00A 2WVJA 1Y1CA 1CT2I 1U5KA 1TBNA 2ORWA 2BUSA 3RU0A 3VDUA 1R79A 4UXJA 2JZMA 2A20A 2NU2I 2L8EA 2OD1A 4UXHA 5CCLA 2QQCA 1R0RI 2GKVA 5DAEA 2ENZA 5HQ8A 4UXIA 2KCXA 3B4VC 3UEYA 1CSOI 1Z7KB 1Y1BA 3UEJA 5FUWA 1TBOA 2E5RA 3BJIA 2YUUA 1Y8FA 2KMPA 1XBTA 2ORVA 1IW4A 1H0ZA 3UGLA 2QPOA 1CHOI 2SGPI 4HGUA 1TGSI 1IY5A 2SGEI 1CGJI 3E59A 5HI7A 1CT4I 1TOTA 2B8TA 1DS3I 2J9RA 3OXLA 5FUYA 2JYYA 2NU4I 1OMTA 2ELIA 2QQ0A 1W4RA 1UUCA 1BMOA 1TBQR 1AN1I 2P6AC 3UGIA 2SGQI 4B6DA 1FARA 2N52A 1MT1A 1M8BA 3UFFA 1CT0I 2N1AB 2W0TA 1KBFA 1TUSA 1PPFI 1OMUA 3OVOA 5EX0A 2ENNA 2FNFX 2V1CC 2ODDA 2KMOA 1V1HA 2NU3I 1PTRA 1XX6A 2JXDA 1SGYI 2VRWB 1OVOA 1CE3A 1CGII 1LR8A 1M8CA 3SGBI 1SGRI 1V1IA 1HPTA 2GKRI 1PTQA 1PCEA 3FC3A 1HJAI 1FAQA 2DB6A 5EX3A 2NU0I 5FUXA 1NUBA 1SGDI 2V53A 4OVOA 2N17A 2ROWA 1N13A 3SEKC 2WCYA 2UZ3A 1YTPA 4SGBI 1TURA 2B0UC 3UGDA 3SGQI 1SGPI 2F3CI 5CCMA 3GOXA 2OVOA 1SGQI 2N71A 1YU6C 2JA1A 2SGDI 4L9MA 2L7XA 4JCVE 3CXLA 1SGEI 2LEOA 3TJQA 3VE5A 1DS2I 3MEKA 3QWPA 1W3SA 4E1RA 2V1CA 1RFHA 1TBRR 1FYBA 2ARPF 2CJSC 3VDPA 5JHWC 1PJUA 2NU1I 3E2IA 4A24A 2M5XA 1UVGA 4E1PA 1SGNI 3OXFA 1LR7A 1HDLA 1TIHA 2ERWA 3QTLD 1IY6A 5FUVA 1UVFA 2YQPA 2QQDA 1KBEA 2DIPA 2KMQA 1LR9A 1X74A 2XRCA 3OL0A 1XA6A 4FKDA 1X4SA 3HH2C 1BUSA 1VDDA 2J87A 2JW6A 1KMAA 2LUYA 2SGFI 1OYVI 3OXGA 3PDNA 2E73A 2KMRA 2GVIA 4GI3C 2GKTI 3KY9A 2QQEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Y1C A;  1CT2 I;  2BUS A;  2JZM A;  2NU2 I;  2QQC A;  1R0R I;  2GKV A;  5DAE A;  2KCX A;  3B4V C;  1CSO I;  1Z7K B;  1Y1B A;  2KMP A;  1IW4 A;  1H0Z A;  1CHO I;  2SGP I;  4HGU A;  1TGS I;  1IY5 A;  2SGE I;  1CGJ I;  1CT4 I;  1DS3 I;  2JYY A;  2NU4 I;  1OMT A;  1UUC A;  1BMO A;  1TBQ R;  1AN1 I;  2P6A C;  2SGQ I;  2N52 A;  1MT1 A;  1M8B A;  1CT0 I;  1TUS A;  1PPF I;  1OMU A;  3OVO A;  2KMO A;  2NU3 I;  2JXD A;  1SGY I;  1OVO A;  1CE3 A;  1CGI I;  1LR8 A;  1M8C A;  3SGB I;  1SGR I;  1HPT A;  2GKR I;  1PCE A;  1HJA I;  2NU0 I;  1NUB A;  1SGD I;  2V53 A;  4OVO A;  2N17 A;  1N13 A;  3SEK C;  2WCY A;  1YTP A;  4SGB I;  1TUR A;  2B0U C;  3SGQ I;  1SGP I;  2F3C I;  2OVO A;  1SGQ I;  2N71 A;  1YU6 C;  2SGD I;  1SGE I;  2LEO A;  3TJQ A;  1DS2 I;  1TBR R;  1FYB A;  2ARP F;  5JHW C;  1PJU A;  2NU1 I;  2M5X A;  1UVG A;  1SGN I;  1HDL A;  1LR7 A;  1TIH A;  2ERW A;  3QTL D;  1IY6 A;  1UVF A;  2QQD A;  2KMQ A;  2XRC A;  1LR9 A;  1BUS A;  3HH2 C;  1KMA A;  2SGF I;  1OYV I;  2KMR A;  4GI3 C;  2GKT I; 
#chains in the Genus database with same CATH topology
 2K9H A;  3D00 A;  2WVJ A;  1Y1C A;  1CT2 I;  1NXU A;  1U5K A;  1TBN A;  2ORW A;  2BUS A;  3RU0 A;  3VDU A;  1FY7 A;  1R79 A;  4UXJ A;  2JZM A;  2A20 A;  2NU2 I;  2L8E A;  2OD1 A;  4UXH A;  1WGC A;  2QQC A;  1R0R I;  2GKV A;  5DAE A;  5CCL A;  2ENZ A;  5HQ8 A;  1WKX A;  2KCX A;  2X3T A;  4MPI A;  4UXI A;  7WGA A;  3B4V C;  3UEY A;  1CSO I;  2CWF A;  1Z7K B;  1Y1B A;  3UEJ A;  5FUW A;  1TBO A;  2E5R A;  1ULM A;  3BJI A;  2YUU A;  1Y8F A;  2KMP A;  3R5D A;  3R5B A;  1XBT A;  2ORV A;  1IW4 A;  1H0Z A;  3UGL A;  1S20 A;  2QPO A;  3QAH A;  1CHO I;  2SGP I;  2LB7 A;  4HGU A;  1TGS I;  1ULN A;  1IY5 A;  2SGE I;  1CGJ I;  3E59 A;  5HI7 A;  1CT4 I;  1Q9B A;  1TOT A;  2B8T A;  1DS3 I;  2J9R A;  3OXL A;  5FUY A;  2JYY A;  2NU4 I;  1OMT A;  2ELI A;  5E3P A;  1WTJ A;  1P9G A;  2QQ0 A;  1W4R A;  1UUC A;  1BMO A;  1MJ9 A;  1AN1 I;  1TBQ R;  2P6A C;  3UGI A;  3UOE A;  2SGQ I;  4B6D A;  1FAR A;  1WGT A;  5J8C A;  2N52 A;  1MT1 A;  1M8B A;  1UHA A;  2GIV A;  3UFF A;  1CT0 I;  2N1A B;  2W0T A;  1KBF A;  1TUS A;  1PPF I;  1OMU A;  3OVO A;  3R5A A;  5EX0 A;  2ENN A;  2FNF X;  2V1C C;  2ODD A;  2KMO A;  1V1H A;  2NU3 I;  1PTR A;  1XX6 A;  2JXD A;  1SGY I;  2VRW B;  3TO7 A;  1OVO A;  1CE3 A;  1CGI I;  1LR8 A;  5J8F A;  1M8C A;  3SGB I;  1SGR I;  1V1I A;  1HPT A;  2GKR I;  1PTQ A;  1PCE A;  9WGA A;  2UVO A;  3FC3 A;  1HJA I;  1K7V A;  1FAQ A;  1K7T A;  2WGC A;  2DB6 A;  5EX3 A;  2NU0 I;  2CWH A;  5FUX A;  1NUB A;  1SGD I;  2V53 A;  3TOB A;  4OVO A;  2N17 A;  2ROW A;  1N13 A;  3TO9 A;  3SEK C;  2WCY A;  2UZ3 A;  1YTP A;  4SGB I;  1TUR A;  2B0U C;  3UGD A;  3SGQ I;  1P9Z A;  1SGP I;  2F3C I;  4DNC A;  5CCM A;  3GOX A;  2X52 A;  2OVO A;  1SGQ I;  2N71 A;  1YU6 C;  5E3R A;  2JA1 A;  2SGD I;  4L9M A;  2L7X A;  4JCV E;  3CXL A;  1SGE I;  2LEO A;  3TJQ A;  3VE5 A;  2OZU A;  1DS2 I;  2RIJ A;  3MEK A;  1W3S A;  2DKV A;  3QWP A;  4E1R A;  4AML A;  1MJA A;  2V1C A;  2CWG A;  3TO6 A;  2OU2 A;  3R5C A;  1RFH A;  3TOA A;  1TBR R;  1FYB A;  5E3Q A;  2ARP F;  2CJS C;  3VDP A;  5JHW C;  1PJU A;  2NU1 I;  3E2I A;  4A24 A;  1K7U A;  2RC4 A;  1Z2I A;  2M5X A;  1UVG A;  4E1P A;  1SGN I;  3OXF A;  1LR7 A;  2PQ8 A;  1HDL A;  1TIH A;  2ERW A;  1HEV A;  3QTL D;  1MJB A;  1IY6 A;  5FUV A;  1UVF A;  2YQP A;  2QQD A;  1KBE A;  2DIP A;  2KMQ A;  1LR9 A;  1X74 A;  2XRC A;  3OL0 A;  4WP4 A;  1XA6 A;  4FKD A;  1X4S A;  3HH2 C;  1BUS A;  1VDD A;  2J87 A;  2JW6 A;  1KMA A;  2LUY A;  2SGF I;  1OYV I;  3OXG A;  3PDN A;  2E73 A;  3FSX A;  2KMR A;  1ULK A;  2GVI A;  2Y0M A;  2GKT I;  4GI3 C;  3KY9 A;  3FSY A;  2QQE A; 
#chains in the Genus database with same CATH homology
 2K9H A;  3D00 A;  2WVJ A;  1Y1C A;  1CT2 I;  1U5K A;  1TBN A;  2ORW A;  2BUS A;  3RU0 A;  3VDU A;  1R79 A;  4UXJ A;  2JZM A;  2A20 A;  2NU2 I;  2L8E A;  2OD1 A;  4UXH A;  5CCL A;  2QQC A;  1R0R I;  2GKV A;  5DAE A;  2ENZ A;  5HQ8 A;  4UXI A;  2KCX A;  3B4V C;  3UEY A;  1CSO I;  1Z7K B;  1Y1B A;  3UEJ A;  5FUW A;  1TBO A;  2E5R A;  3BJI A;  2YUU A;  1Y8F A;  2KMP A;  1XBT A;  2ORV A;  1IW4 A;  1H0Z A;  3UGL A;  2QPO A;  1CHO I;  2SGP I;  4HGU A;  1TGS I;  1IY5 A;  2SGE I;  1CGJ I;  3E59 A;  5HI7 A;  1CT4 I;  1TOT A;  2B8T A;  1DS3 I;  2J9R A;  3OXL A;  5FUY A;  2JYY A;  2NU4 I;  1OMT A;  2ELI A;  2QQ0 A;  1W4R A;  1UUC A;  1BMO A;  1TBQ R;  1AN1 I;  2P6A C;  3UGI A;  2SGQ I;  4B6D A;  1FAR A;  2N52 A;  1MT1 A;  1M8B A;  3UFF A;  1CT0 I;  2N1A B;  2W0T A;  1KBF A;  1TUS A;  1PPF I;  1OMU A;  3OVO A;  5EX0 A;  2ENN A;  2FNF X;  2V1C C;  2ODD A;  2KMO A;  1V1H A;  2NU3 I;  1PTR A;  1XX6 A;  2JXD A;  1SGY I;  2VRW B;  1OVO A;  1CE3 A;  1CGI I;  1LR8 A;  1M8C A;  3SGB I;  1SGR I;  1V1I A;  1HPT A;  2GKR I;  1PTQ A;  1PCE A;  3FC3 A;  1HJA I;  1FAQ A;  2DB6 A;  5EX3 A;  2NU0 I;  5FUX A;  1NUB A;  1SGD I;  2V53 A;  4OVO A;  2N17 A;  2ROW A;  1N13 A;  3SEK C;  2WCY A;  2UZ3 A;  1YTP A;  4SGB I;  1TUR A;  2B0U C;  3UGD A;  3SGQ I;  1SGP I;  2F3C I;  5CCM A;  3GOX A;  2OVO A;  1SGQ I;  2N71 A;  1YU6 C;  2JA1 A;  2SGD I;  4L9M A;  2L7X A;  4JCV E;  3CXL A;  1SGE I;  2LEO A;  3TJQ A;  3VE5 A;  1DS2 I;  3MEK A;  3QWP A;  1W3S A;  4E1R A;  2V1C A;  1RFH A;  1TBR R;  1FYB A;  2ARP F;  2CJS C;  3VDP A;  5JHW C;  1PJU A;  2NU1 I;  3E2I A;  4A24 A;  2M5X A;  1UVG A;  4E1P A;  1SGN I;  3OXF A;  1LR7 A;  1HDL A;  1TIH A;  2ERW A;  3QTL D;  1IY6 A;  5FUV A;  1UVF A;  2YQP A;  2QQD A;  1KBE A;  2DIP A;  2KMQ A;  1LR9 A;  1X74 A;  2XRC A;  3OL0 A;  1XA6 A;  4FKD A;  1X4S A;  3HH2 C;  1BUS A;  1VDD A;  2J87 A;  2JW6 A;  1KMA A;  2LUY A;  2SGF I;  1OYV I;  3OXG A;  3PDN A;  2E73 A;  2KMR A;  2GVI A;  4GI3 C;  2GKT I;  3KY9 A;  2QQE A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...