2KMVA

Solution structure of the nucleotide binding domain of the human menkes protein in the atp-free form
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
185
structure length
185
Chain Sequence
SFTMHGTPVVNQVKVLTESNRISHHKILAIVGTAESNSEHPLGTAITKYCKQELDTETLGTCIDFQVVPGCGISCKVTNIEGLLHKNNWNIEDNNIKNASLVQIDASNEQSSTSSSMIIDAQISNALNAQQYKVLIGNREWMIRNGLVINNDVNDFMTEHERKGRTAVLVAVDDELCGLIAIADT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The binding mode of ATP revealed by the solution structure of the N-domain of human ATP7A.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Copper-transporting ATPase 1
total genus 35
structure length 185
sequence length 185
ec nomenclature ec 7.2.2.8: P-type Cu(+) transporter.
pdb deposition date 2009-08-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1110.10 Alpha Beta 3-Layer(aba) Sandwich Calcium-transporting ATPase, cytoplasmic domain N Calcium-transporting ATPase, cytoplasmic domain N 2kmvA01
2A00A 3AR8A 3FGOA 2EAUA 2A29A 5AW8A 5AVYA 2EATA 3SKYA 4UMVA 2ZBDA 1T5SA 5AVZA 3W5DA 3AR3A 5AW4A 2B8EA 3B8EA 1MO8A 5AVSA 4XE5A 5AW7A 2BY4A 3N5KA 5AVXA 3A3YA 3KDPA 5A3RA 1IWOA 5AW2A 2YJ5A 2EARA 5AW1A 5AW5A 2YFYA 3SKXA 4KYTA 2YJ3A 2ZXEA 3WGVA 2AGVA 4BEWA 2ZBGA 5AVQA 4BBJA 3A1CA 2ZBEA 3BA6A 3W5BA 3AR2A 3W5CA 5AW9A 1XP5A 4BYGA 3A1EA 2YJ6A 4YCNA 3B9BA 3A1DA 3W5AA 5AW0A 2C8LA 3N8GA 1WPGA 5AVWA 5AVUA 3AR9A 4RESA 5A3SA 2KMXA 2C88A 2YJ4A 4RETA 3FPBA 2DQSA 3AR4A 1MO7A 1VFPA 4NABA 3NAMA 3NANA 3AR7A 3AR6A 5AVVA 2ZBFA 2KMVA 4XOUA 2ARFA 4YCMA 3B9RA 4BEVA 2IYEA 5AVRA 3TLMA 2O9JA 3FPSA 1T5TA 4UU0A 3RFUA 5AW6A 3WGUA 4HYTA 2C9MA 5AW3A 1U7QA 3GWIA 3J7TA 5AVTA 3AR5A 1Q3IA 4YCLA 2C8KA 4J2TA 1SU4A 2OA0A 3NALA 4UU1A 1SVJA 4H1WA 4Y3UA 5A3QA
chains in the Genus database with same CATH superfamily
2A00A 3AR8A 3FGOA 2EAUA 2A29A 5AW8A 5AVYA 2EATA 3SKYA 4UMVA 2ZBDA 1T5SA 5AVZA 3W5DA 3AR3A 5AW4A 2B8EA 3B8EA 1MO8A 5AVSA 4XE5A 5AW7A 2BY4A 3N5KA 5AVXA 3A3YA 3KDPA 5A3RA 1IWOA 5AW2A 2YJ5A 2EARA 5AW1A 5AW5A 2YFYA 3SKXA 4KYTA 2YJ3A 2ZXEA 3WGVA 2AGVA 4BEWA 2ZBGA 5AVQA 4BBJA 3A1CA 2ZBEA 3BA6A 3W5BA 3AR2A 3W5CA 5AW9A 1XP5A 4BYGA 3A1EA 2YJ6A 4YCNA 3B9BA 3A1DA 3W5AA 5AW0A 2C8LA 3N8GA 1WPGA 5AVWA 5AVUA 3AR9A 4RESA 5A3SA 2KMXA 2C88A 2YJ4A 4RETA 3FPBA 2DQSA 3AR4A 1MO7A 1VFPA 4NABA 3NAMA 3NANA 3AR7A 3AR6A 5AVVA 2ZBFA 2KMVA 4XOUA 2ARFA 4YCMA 3B9RA 4BEVA 2IYEA 5AVRA 3TLMA 2O9JA 3FPSA 1T5TA 4UU0A 3RFUA 5AW6A 3WGUA 4HYTA 2C9MA 5AW3A 1U7QA 3GWIA 3J7TA 5AVTA 3AR5A 1Q3IA 4YCLA 2C8KA 4J2TA 1SU4A 2OA0A 3NALA 4UU1A 1SVJA 4H1WA 4Y3UA 5A3QA
chains in the Genus database with same CATH topology
2A00A 3AR8A 3FGOA 2EAUA 2A29A 5AW8A 5AVYA 2EATA 3SKYA 4UMVA 2ZBDA 1T5SA 5AVZA 3W5DA 3AR3A 5AW4A 2B8EA 3B8EA 1MO8A 5AVSA 4XE5A 5AW7A 2BY4A 3N5KA 5AVXA 3A3YA 3KDPA 5A3RA 1IWOA 5AW2A 2YJ5A 2EARA 5AW1A 5AW5A 2YFYA 3SKXA 4KYTA 2YJ3A 2ZXEA 3WGVA 2AGVA 4BEWA 2ZBGA 5AVQA 4BBJA 3A1CA 2ZBEA 3BA6A 3W5BA 3AR2A 3W5CA 5AW9A 1XP5A 4BYGA 3A1EA 2YJ6A 4YCNA 3B9BA 3A1DA 3W5AA 5AW0A 2C8LA 3N8GA 1WPGA 5AVWA 5AVUA 3AR9A 4RESA 5A3SA 2KMXA 2C88A 2YJ4A 4RETA 3FPBA 2DQSA 3AR4A 1MO7A 1VFPA 4NABA 3NAMA 3NANA 3AR7A 3AR6A 5AVVA 2ZBFA 2KMVA 4XOUA 2ARFA 4YCMA 3B9RA 4BEVA 2IYEA 5AVRA 3TLMA 2O9JA 3FPSA 1T5TA 4UU0A 3RFUA 5AW6A 3WGUA 4HYTA 2C9MA 5AW3A 1U7QA 3GWIA 3J7TA 5AVTA 3AR5A 1Q3IA 4YCLA 2C8KA 4J2TA 1SU4A 2OA0A 3NALA 4UU1A 1SVJA 4H1WA 4Y3UA 5A3QA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2A00 A;  3AR8 A;  3FGO A;  2EAU A;  2A29 A;  5AW8 A;  5AVY A;  2EAT A;  3SKY A;  4UMV A;  2ZBD A;  1T5S A;  5AVZ A;  3W5D A;  3AR3 A;  5AW4 A;  2B8E A;  3B8E A;  1MO8 A;  5AVS A;  4XE5 A;  5AW7 A;  2BY4 A;  3N5K A;  5AVX A;  3A3Y A;  3KDP A;  5A3R A;  1IWO A;  5AW2 A;  2YJ5 A;  2EAR A;  5AW1 A;  5AW5 A;  2YFY A;  3SKX A;  4KYT A;  2YJ3 A;  2ZXE A;  3WGV A;  2AGV A;  4BEW A;  2ZBG A;  5AVQ A;  4BBJ A;  3A1C A;  2ZBE A;  3BA6 A;  3W5B A;  3AR2 A;  3W5C A;  5AW9 A;  1XP5 A;  4BYG A;  3A1E A;  2YJ6 A;  4YCN A;  3B9B A;  3A1D A;  3W5A A;  5AW0 A;  2C8L A;  3N8G A;  1WPG A;  5AVW A;  5AVU A;  3AR9 A;  4RES A;  5A3S A;  2KMX A;  2C88 A;  2YJ4 A;  4RET A;  3FPB A;  2DQS A;  3AR4 A;  1MO7 A;  1VFP A;  4NAB A;  3NAM A;  3NAN A;  3AR7 A;  3AR6 A;  5AVV A;  2ZBF A;  2KMV A;  4XOU A;  2ARF A;  4YCM A;  3B9R A;  4BEV A;  2IYE A;  5AVR A;  3TLM A;  2O9J A;  3FPS A;  1T5T A;  4UU0 A;  3RFU A;  5AW6 A;  3WGU A;  4HYT A;  2C9M A;  5AW3 A;  1U7Q A;  3GWI A;  3J7T A;  5AVT A;  3AR5 A;  1Q3I A;  4YCL A;  2C8K A;  4J2T A;  1SU4 A;  2OA0 A;  3NAL A;  4UU1 A;  1SVJ A;  4H1W A;  4Y3U A;  5A3Q A; 
#chains in the Genus database with same CATH topology
 2A00 A;  3AR8 A;  3FGO A;  2EAU A;  2A29 A;  5AW8 A;  5AVY A;  2EAT A;  3SKY A;  4UMV A;  2ZBD A;  1T5S A;  5AVZ A;  3W5D A;  3AR3 A;  5AW4 A;  2B8E A;  3B8E A;  1MO8 A;  5AVS A;  4XE5 A;  5AW7 A;  2BY4 A;  3N5K A;  5AVX A;  3A3Y A;  3KDP A;  5A3R A;  1IWO A;  5AW2 A;  2YJ5 A;  2EAR A;  5AW1 A;  5AW5 A;  2YFY A;  3SKX A;  4KYT A;  2YJ3 A;  2ZXE A;  3WGV A;  2AGV A;  4BEW A;  2ZBG A;  5AVQ A;  4BBJ A;  3A1C A;  2ZBE A;  3BA6 A;  3W5B A;  3AR2 A;  3W5C A;  5AW9 A;  1XP5 A;  4BYG A;  3A1E A;  2YJ6 A;  4YCN A;  3B9B A;  3A1D A;  3W5A A;  5AW0 A;  2C8L A;  3N8G A;  1WPG A;  5AVW A;  5AVU A;  3AR9 A;  4RES A;  5A3S A;  2KMX A;  2C88 A;  2YJ4 A;  4RET A;  3FPB A;  2DQS A;  3AR4 A;  1MO7 A;  1VFP A;  4NAB A;  3NAM A;  3NAN A;  3AR7 A;  3AR6 A;  5AVV A;  2ZBF A;  2KMV A;  4XOU A;  2ARF A;  4YCM A;  3B9R A;  4BEV A;  2IYE A;  5AVR A;  3TLM A;  2O9J A;  3FPS A;  1T5T A;  4UU0 A;  3RFU A;  5AW6 A;  3WGU A;  4HYT A;  2C9M A;  5AW3 A;  1U7Q A;  3GWI A;  3J7T A;  5AVT A;  3AR5 A;  1Q3I A;  4YCL A;  2C8K A;  4J2T A;  1SU4 A;  2OA0 A;  3NAL A;  4UU1 A;  1SVJ A;  4H1W A;  4Y3U A;  5A3Q A; 
#chains in the Genus database with same CATH homology
 2A00 A;  3AR8 A;  3FGO A;  2EAU A;  2A29 A;  5AW8 A;  5AVY A;  2EAT A;  3SKY A;  4UMV A;  2ZBD A;  1T5S A;  5AVZ A;  3W5D A;  3AR3 A;  5AW4 A;  2B8E A;  3B8E A;  1MO8 A;  5AVS A;  4XE5 A;  5AW7 A;  2BY4 A;  3N5K A;  5AVX A;  3A3Y A;  3KDP A;  5A3R A;  1IWO A;  5AW2 A;  2YJ5 A;  2EAR A;  5AW1 A;  5AW5 A;  2YFY A;  3SKX A;  4KYT A;  2YJ3 A;  2ZXE A;  3WGV A;  2AGV A;  4BEW A;  2ZBG A;  5AVQ A;  4BBJ A;  3A1C A;  2ZBE A;  3BA6 A;  3W5B A;  3AR2 A;  3W5C A;  5AW9 A;  1XP5 A;  4BYG A;  3A1E A;  2YJ6 A;  4YCN A;  3B9B A;  3A1D A;  3W5A A;  5AW0 A;  2C8L A;  3N8G A;  1WPG A;  5AVW A;  5AVU A;  3AR9 A;  4RES A;  5A3S A;  2KMX A;  2C88 A;  2YJ4 A;  4RET A;  3FPB A;  2DQS A;  3AR4 A;  1MO7 A;  1VFP A;  4NAB A;  3NAM A;  3NAN A;  3AR7 A;  3AR6 A;  5AVV A;  2ZBF A;  2KMV A;  4XOU A;  2ARF A;  4YCM A;  3B9R A;  4BEV A;  2IYE A;  5AVR A;  3TLM A;  2O9J A;  3FPS A;  1T5T A;  4UU0 A;  3RFU A;  5AW6 A;  3WGU A;  4HYT A;  2C9M A;  5AW3 A;  1U7Q A;  3GWI A;  3J7T A;  5AVT A;  3AR5 A;  1Q3I A;  4YCL A;  2C8K A;  4J2T A;  1SU4 A;  2OA0 A;  3NAL A;  4UU1 A;  1SVJ A;  4H1W A;  4Y3U A;  5A3Q A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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