2KMXA

Solution structure of the nucleotide binding domain of the human menkes protein in the atp-bound form
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
185
structure length
185
Chain Sequence
SFTMHGTPVVNQVKVLTESNRISHHKILAIVGTAESNSEHPLGTAITKYCKQELDTETLGTCIDFQVVPGCGISCKVTNIEGLLHKNNWNIEDNNIKNASLVQIDASNEQSSTSSSMIIDAQISNALNAQQYKVLIGNREWMIRNGLVINNDVNDFMTEHERKGRTAVLVAVDDELCGLIAIADT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The binding mode of ATP revealed by the solution structure of the N-domain of human ATP7A.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Copper-transporting ATPase 1
total genus 39
structure length 185
sequence length 185
ec nomenclature ec 7.2.2.8: P-type Cu(+) transporter.
pdb deposition date 2009-08-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1110.10 Alpha Beta 3-Layer(aba) Sandwich Calcium-transporting ATPase, cytoplasmic domain N Calcium-transporting ATPase, cytoplasmic domain N 2kmxA00
4BEWA 2BY4A 2ARFA 4XE5A 1MO7A 1VFPA 3AR6A 5AW1A 3W5CA 3W5AA 5AW0A 4XOUA 5A3SA 3GWIA 5A3RA 3TLMA 1Q3IA 2ZBEA 4BBJA 3AR4A 3NALA 3WGUA 2ZBDA 2YJ3A 5AVRA 3N5KA 4J2TA 3AR2A 4UU1A 1T5TA 5AVUA 2C9MA 2C8KA 1XP5A 2KMVA 4KYTA 2YJ6A 1WPGA 4H1WA 5AVZA 1MO8A 4RETA 4YCMA 4UU0A 2ZXEA 2C8LA 5AW4A 5AW7A 5AVSA 3AR8A 2AGVA 4BEVA 1SVJA 2IYEA 3A3YA 5AVXA 4BYGA 2C88A 5AW8A 2DQSA 2EARA 3A1CA 3KDPA 5AVYA 2KMXA 4Y3UA 5AW3A 2OA0A 3W5DA 3SKYA 5AW5A 3B9BA 4YCLA 1SU4A 2ZBGA 1U7QA 5AVVA 3AR5A 5AW9A 2YFYA 3NANA 3B9RA 4UMVA 3BA6A 3SKXA 1IWOA 5AVWA 2O9JA 3J7TA 3AR9A 4RESA 2YJ4A 3WGVA 3NAMA 4NABA 3RFUA 4HYTA 5AVTA 2YJ5A 2A00A 3A1DA 4YCNA 3B8EA 3W5BA 5AW6A 3AR7A 2EATA 2ZBFA 2A29A 3A1EA 3FPSA 3FPBA 5AVQA 3FGOA 1T5SA 3N8GA 3AR3A 5AW2A 2B8EA 5A3QA 2EAUA
chains in the Genus database with same CATH superfamily
4BEWA 2BY4A 2ARFA 4XE5A 1MO7A 1VFPA 3AR6A 5AW1A 3W5CA 3W5AA 5AW0A 4XOUA 5A3SA 3GWIA 5A3RA 3TLMA 1Q3IA 2ZBEA 4BBJA 3AR4A 3NALA 3WGUA 2ZBDA 2YJ3A 5AVRA 3N5KA 4J2TA 3AR2A 4UU1A 1T5TA 5AVUA 2C9MA 2C8KA 1XP5A 2KMVA 4KYTA 2YJ6A 1WPGA 4H1WA 5AVZA 1MO8A 4RETA 4YCMA 4UU0A 2ZXEA 2C8LA 5AW4A 5AW7A 5AVSA 3AR8A 2AGVA 4BEVA 1SVJA 2IYEA 3A3YA 5AVXA 4BYGA 2C88A 5AW8A 2DQSA 2EARA 3A1CA 3KDPA 5AVYA 2KMXA 4Y3UA 5AW3A 2OA0A 3W5DA 3SKYA 5AW5A 3B9BA 4YCLA 1SU4A 2ZBGA 1U7QA 5AVVA 3AR5A 5AW9A 2YFYA 3NANA 3B9RA 4UMVA 3BA6A 3SKXA 1IWOA 5AVWA 2O9JA 3J7TA 3AR9A 4RESA 2YJ4A 3WGVA 3NAMA 4NABA 3RFUA 4HYTA 5AVTA 2YJ5A 2A00A 3A1DA 4YCNA 3B8EA 3W5BA 5AW6A 3AR7A 2EATA 2ZBFA 2A29A 3A1EA 3FPSA 3FPBA 5AVQA 3FGOA 1T5SA 3N8GA 3AR3A 5AW2A 2B8EA 5A3QA 2EAUA
chains in the Genus database with same CATH topology
4BEWA 2BY4A 2ARFA 4XE5A 1MO7A 1VFPA 3AR6A 5AW1A 3W5CA 3W5AA 5AW0A 4XOUA 5A3SA 3GWIA 5A3RA 3TLMA 1Q3IA 2ZBEA 4BBJA 3AR4A 3NALA 3WGUA 2ZBDA 2YJ3A 5AVRA 3N5KA 4J2TA 3AR2A 4UU1A 1T5TA 5AVUA 2C9MA 2C8KA 1XP5A 2KMVA 4KYTA 2YJ6A 1WPGA 4H1WA 5AVZA 1MO8A 4RETA 4YCMA 4UU0A 2ZXEA 2C8LA 5AW4A 5AW7A 5AVSA 3AR8A 2AGVA 4BEVA 1SVJA 2IYEA 3A3YA 5AVXA 4BYGA 2C88A 5AW8A 2DQSA 2EARA 3A1CA 3KDPA 5AVYA 2KMXA 4Y3UA 5AW3A 2OA0A 3W5DA 3SKYA 5AW5A 3B9BA 4YCLA 1SU4A 2ZBGA 1U7QA 5AVVA 3AR5A 5AW9A 2YFYA 3NANA 3B9RA 4UMVA 3BA6A 3SKXA 1IWOA 5AVWA 2O9JA 3J7TA 3AR9A 4RESA 2YJ4A 3WGVA 3NAMA 4NABA 3RFUA 4HYTA 5AVTA 2YJ5A 2A00A 3A1DA 4YCNA 3B8EA 3W5BA 5AW6A 3AR7A 2EATA 2ZBFA 2A29A 3A1EA 3FPSA 3FPBA 5AVQA 3FGOA 1T5SA 3N8GA 3AR3A 5AW2A 2B8EA 5A3QA 2EAUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BEW A;  2BY4 A;  2ARF A;  4XE5 A;  1MO7 A;  1VFP A;  3AR6 A;  5AW1 A;  3W5C A;  3W5A A;  5AW0 A;  4XOU A;  5A3S A;  3GWI A;  5A3R A;  3TLM A;  1Q3I A;  2ZBE A;  4BBJ A;  3AR4 A;  3NAL A;  3WGU A;  2ZBD A;  2YJ3 A;  5AVR A;  3N5K A;  4J2T A;  3AR2 A;  4UU1 A;  1T5T A;  5AVU A;  2C9M A;  2C8K A;  1XP5 A;  2KMV A;  4KYT A;  2YJ6 A;  1WPG A;  4H1W A;  5AVZ A;  1MO8 A;  4RET A;  4YCM A;  4UU0 A;  2ZXE A;  2C8L A;  5AW4 A;  5AW7 A;  5AVS A;  3AR8 A;  2AGV A;  4BEV A;  1SVJ A;  2IYE A;  3A3Y A;  5AVX A;  4BYG A;  2C88 A;  5AW8 A;  2DQS A;  2EAR A;  3A1C A;  3KDP A;  5AVY A;  2KMX A;  4Y3U A;  5AW3 A;  2OA0 A;  3W5D A;  3SKY A;  5AW5 A;  3B9B A;  4YCL A;  1SU4 A;  2ZBG A;  1U7Q A;  5AVV A;  3AR5 A;  5AW9 A;  2YFY A;  3NAN A;  3B9R A;  4UMV A;  3BA6 A;  3SKX A;  1IWO A;  5AVW A;  2O9J A;  3J7T A;  3AR9 A;  4RES A;  2YJ4 A;  3WGV A;  3NAM A;  4NAB A;  3RFU A;  4HYT A;  5AVT A;  2YJ5 A;  2A00 A;  3A1D A;  4YCN A;  3B8E A;  3W5B A;  5AW6 A;  3AR7 A;  2EAT A;  2ZBF A;  2A29 A;  3A1E A;  3FPS A;  3FPB A;  5AVQ A;  3FGO A;  1T5S A;  3N8G A;  3AR3 A;  5AW2 A;  2B8E A;  5A3Q A;  2EAU A; 
#chains in the Genus database with same CATH topology
 4BEW A;  2BY4 A;  2ARF A;  4XE5 A;  1MO7 A;  1VFP A;  3AR6 A;  5AW1 A;  3W5C A;  3W5A A;  5AW0 A;  4XOU A;  5A3S A;  3GWI A;  5A3R A;  3TLM A;  1Q3I A;  2ZBE A;  4BBJ A;  3AR4 A;  3NAL A;  3WGU A;  2ZBD A;  2YJ3 A;  5AVR A;  3N5K A;  4J2T A;  3AR2 A;  4UU1 A;  1T5T A;  5AVU A;  2C9M A;  2C8K A;  1XP5 A;  2KMV A;  4KYT A;  2YJ6 A;  1WPG A;  4H1W A;  5AVZ A;  1MO8 A;  4RET A;  4YCM A;  4UU0 A;  2ZXE A;  2C8L A;  5AW4 A;  5AW7 A;  5AVS A;  3AR8 A;  2AGV A;  4BEV A;  1SVJ A;  2IYE A;  3A3Y A;  5AVX A;  4BYG A;  2C88 A;  5AW8 A;  2DQS A;  2EAR A;  3A1C A;  3KDP A;  5AVY A;  2KMX A;  4Y3U A;  5AW3 A;  2OA0 A;  3W5D A;  3SKY A;  5AW5 A;  3B9B A;  4YCL A;  1SU4 A;  2ZBG A;  1U7Q A;  5AVV A;  3AR5 A;  5AW9 A;  2YFY A;  3NAN A;  3B9R A;  4UMV A;  3BA6 A;  3SKX A;  1IWO A;  5AVW A;  2O9J A;  3J7T A;  3AR9 A;  4RES A;  2YJ4 A;  3WGV A;  3NAM A;  4NAB A;  3RFU A;  4HYT A;  5AVT A;  2YJ5 A;  2A00 A;  3A1D A;  4YCN A;  3B8E A;  3W5B A;  5AW6 A;  3AR7 A;  2EAT A;  2ZBF A;  2A29 A;  3A1E A;  3FPS A;  3FPB A;  5AVQ A;  3FGO A;  1T5S A;  3N8G A;  3AR3 A;  5AW2 A;  2B8E A;  5A3Q A;  2EAU A; 
#chains in the Genus database with same CATH homology
 4BEW A;  2BY4 A;  2ARF A;  4XE5 A;  1MO7 A;  1VFP A;  3AR6 A;  5AW1 A;  3W5C A;  3W5A A;  5AW0 A;  4XOU A;  5A3S A;  3GWI A;  5A3R A;  3TLM A;  1Q3I A;  2ZBE A;  4BBJ A;  3AR4 A;  3NAL A;  3WGU A;  2ZBD A;  2YJ3 A;  5AVR A;  3N5K A;  4J2T A;  3AR2 A;  4UU1 A;  1T5T A;  5AVU A;  2C9M A;  2C8K A;  1XP5 A;  2KMV A;  4KYT A;  2YJ6 A;  1WPG A;  4H1W A;  5AVZ A;  1MO8 A;  4RET A;  4YCM A;  4UU0 A;  2ZXE A;  2C8L A;  5AW4 A;  5AW7 A;  5AVS A;  3AR8 A;  2AGV A;  4BEV A;  1SVJ A;  2IYE A;  3A3Y A;  5AVX A;  4BYG A;  2C88 A;  5AW8 A;  2DQS A;  2EAR A;  3A1C A;  3KDP A;  5AVY A;  2KMX A;  4Y3U A;  5AW3 A;  2OA0 A;  3W5D A;  3SKY A;  5AW5 A;  3B9B A;  4YCL A;  1SU4 A;  2ZBG A;  1U7Q A;  5AVV A;  3AR5 A;  5AW9 A;  2YFY A;  3NAN A;  3B9R A;  4UMV A;  3BA6 A;  3SKX A;  1IWO A;  5AVW A;  2O9J A;  3J7T A;  3AR9 A;  4RES A;  2YJ4 A;  3WGV A;  3NAM A;  4NAB A;  3RFU A;  4HYT A;  5AVT A;  2YJ5 A;  2A00 A;  3A1D A;  4YCN A;  3B8E A;  3W5B A;  5AW6 A;  3AR7 A;  2EAT A;  2ZBF A;  2A29 A;  3A1E A;  3FPS A;  3FPB A;  5AVQ A;  3FGO A;  1T5S A;  3N8G A;  3AR3 A;  5AW2 A;  2B8E A;  5A3Q A;  2EAU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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