2KR6A

Solution structure of presenilin-1 ctf subunit
Total Genus 28
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
176
structure length
176
Chain Sequence
b'MVWLVNMAEGDPEAQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEWEAQRDSHLGPHRSTPESRAAVQELSSSILAGEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Presenilin-1
publication title Solution structure of presenilin-1 CTF subunit
rcsb
source organism Homo sapiens
molecule tags Hydrolase
total genus 28
structure length 176
sequence length 176
ec nomenclature ec 3.4.23.-:
pdb deposition date 2009-12-04
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.472.100 Mainly Alpha Orthogonal Bundle Cyclin A; domain 1 Cyclin A; domain 1 2kr6A01
2KR6A
chains in the Genus database with same CATH superfamily
1H25B 2CZ6B 3WVDB 4BY1X 1QLBA 2WMAB 4ELJA 2WXVB 1VINA 4CRLB 2W9ZA 3A8MB 1XO2A 1GUXA 3QYHB 1AD6A 2DPPB 4BCQB 5I5ZB 3A8OB 3BG3A 1VYWB 4F7NB 2WJ9A 4CFNB 4QSHA 4HL4A 5HNBB 1H1RB 3QYBA 4LOCA 5DQWA 1FVVB 4I3ZB 3NDQA 2QDYB 5CEIB 4Y72B 1FKMA 4BCHB 2I53A 3QHRB 1O9KA 3X25B 4ROEA 4KRCB 4KRDB 3K7AM 2PJQA 5EJCA 2WEVB 3BHUB 2I40B 2WHBB 2KR6A 3X26B 3WVEB 1ZP2A 2IVXA 4F6SB 4BCMD 4OB2B 1D3UB 1PKDB 1GY3B 4EOKB 4F6WB 4RODA 2KMGA 4M6VA 4OGRB 2F2CA 1UNGD 3VKHA 1VOLA 3MI9B 2ZPGB 4UN0A 4F6UB 4TTHA 4EOMB 4IMYB 2JGZB 3B57A 2W2HA 2DD5B 2IW8B 2WFYB 4AI6A 4EOQB 5ACBA 4HNVA 2WIHB 1W98B 2WPAB 3BG9A 5EFQB 4NC6A 2CCIB 2DMEA 4BCND 4JX6A 2PK2A 4BBSM 4EC9B 1UGSB 4OB3B 1JSUB 4ROCA 4JX5A 2DXCB 3MY1B 3DDPB 5BNJB 1OKVB 2DXBB 1N4MA 2BKZB 3A8GB 4EOSB 5L2WB 4Z6YA 1H24B 4EOJB 2ZPHB 1JSTB 1OL2B 2ZZDB 4BY7X 2X1NB 1FINB 1P5EB 3TNWB 1OGUB 2CYZB 4F7SB 2UUEB 4II5B 2LW4A 1H1SB 1OL1B 5HBEB 3QYGB 5HBHB 4YOSA 5IF1B 3MY5B 3EOCB 3QHWB 5DQVA 2C5NB 2IW6B 2C6TB 3EIDB 2BS2A 1GH6B 3BHVB 3A8HB 4BCMB 1H27B 4CXAB 2R7GA 3X24B 1G3NC 2G77A 1ENWA 4AKGA 1H1QB 2ZPFB 4MFDA 2C5VB 3A8LB 2V22B 2UZBB 4CFXB 1H28B 1V29B 4EOPB 1JKWA 5CYIB 3M03A 4EOOB 2G9XB 4YOOA 1AHJB 2ZPIB 4BCPB 1GUXB 4AKHA 2IW9B 2QFZA 2B9RA 4CFWB 1UGRB 2QDJA 3TN8B 3HB9A 1OIUB 3DJBA 1UGQB 4AKIA 5LQFB 4F70B 4MIMA 2C5OB 4MFEA 1O9KB 4OB1B 1QMZB 4NSTB 2QF7A 2CZ0B 4OB0B 4YOZA 4FM4B 4EOIB 3TW6A 3DTOA 4CFMB 5HBJB 4CFVB 4FX3B 3HBLA 4OR5B 4F7JB 2BPMB 2ZPBB 4HLQA 4CFUD 3BLHB 3EJ1B 4YC3B 1BU2A 4BBRM 4EC8B 2EUFA 2QQ8A 1E7PA 3KHIA 1OIYB 1C9BA 2CZ7B 3H4CA 3DOGB 2W99A 4BCKB 4EOLB 2PHGA 1UNLD 1URCB 3QZ9B 5IHYA 5HQ0B 2W9FA 3HO8A 4ZGDB 2QGSA 2BS3A 3QWLA 3TNHB 3QXEB 5HVYB 3VYHB 2PK9B 3BHTB 2UZLB 1KXUA 4ZGJB 4BCQD 1OKWB 4BCIB 4EONB 2UZDB 3RGFB 5ICPB 4BXXX 4G6LB 5LMKB 2W96A 4ZGEB 4F7LB 3PO3S 3BG5A 1AISB 2ZPEB 4HNTA 2BS4A 1TD6A 4BCNB 5IDNB 3QZ5B 3LQ5B 4ELLA 3POMA 2WMBB 5FGKB 2PMIB 3G33B 4EORB 1H4LD 3VYGB 1JOWA 4JX4A 4BCOB 1UNHD 3DL1A 3O0GD 3X20B 2CZ1B 2C4GB 1OI9B 3TW7A 1TFBA 4CFUB 3TNIB 2UZEB 2ZCFB 4HNUA 1H26B 3HZJA 5IDPB 3GTMS 3BLRB 2C5XB 3BLQB 2D0QB 1UGPB 3DDQB 1E9HB 4BCFB 4BCGB 2IN3A 3MIAB 1H1PB 1IREB 3X28B 2CCHB 2DD4B 1F5QB 3HHTB 3VKGA 3QYEA 2CJMB 3F5XB 2AHJB 4BCJB 2WIPB
chains in the Genus database with same CATH topology
2CZ6B 3WVDB 1AHJB 1QLBA 2ZPIB 4JX6A 4BBSM 4ELJA 1UGSB 4OB3B 4AKHA 4JX5A 4ZGJB 2QFZA 2DXCB 1UGRB 2QDJA 3A8MB 2DXBB 3QYHB 2DPPB 3A8GB 3HB9A 3A8OB 3BG3A 4Z6YA 4ZGEB 2WJ9A 4QSHA 2ZPHB 1UGQB 3BG5A 4HL4A 4AKIA 2ZPEB 4HNTA 3QYBA 2ZZDB 4LOCA 4MIMA 4MFEA 2BS4A 4OB1B 2QDYB 2QF7A 3QZ5B 2CZ0B 1FKMA 4OB0B 4FM4B 3X25B 3TW6A 2CYZB 3VYGB 4JX4A 3HBLA 2ZPBB 4HLQA 3DL1A 3QYGB 3X20B 5EJCA 2CZ1B 3X26B 2KR6A 3TW7A 3WVEB 4BBRM 2ZCFB 4HNUA 3HZJA 4OB2B 2BS2A 2D0QB 2KMGA 4M6VA 3A8HB 1UGPB 2QQ8A 3VKHA 1E7PA 3KHIA 2ZPGB 3X24B 1IREB 3X28B 2CZ7B 3H4CA 2G77A 2DD5B 2DD4B 4AKGA 2ZPFB 3HHTB 4AI6A 3VKGA 4MFDA 3A8LB 4HNVA 3QZ9B 3QYEA 3HO8A 3BG9A 4ZGDB 2BS3A 3QWLA 4NC6A 1V29B 3QXEB 2AHJB 3VYHB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KR6 A; 
#chains in the Genus database with same CATH topology
 1H25 B;  2CZ6 B;  3WVD B;  4BY1 X;  1QLB A;  2WMA B;  4ELJ A;  2WXV B;  1VIN A;  4CRL B;  2W9Z A;  3A8M B;  1XO2 A;  1GUX A;  3QYH B;  1AD6 A;  2DPP B;  4BCQ B;  5I5Z B;  3A8O B;  3BG3 A;  1VYW B;  4F7N B;  2WJ9 A;  4CFN B;  4QSH A;  4HL4 A;  5HNB B;  1H1R B;  3QYB A;  4LOC A;  5DQW A;  1FVV B;  4I3Z B;  3NDQ A;  2QDY B;  5CEI B;  4Y72 B;  1FKM A;  4BCH B;  2I53 A;  3QHR B;  1O9K A;  3X25 B;  4ROE A;  4KRC B;  4KRD B;  3K7A M;  2PJQ A;  5EJC A;  2WEV B;  3BHU B;  2I40 B;  2WHB B;  2KR6 A;  3X26 B;  3WVE B;  1ZP2 A;  2IVX A;  4F6S B;  4BCM D;  4OB2 B;  1D3U B;  1PKD B;  1GY3 B;  4EOK B;  4F6W B;  4ROD A;  2KMG A;  4M6V A;  4OGR B;  2F2C A;  1UNG D;  3VKH A;  1VOL A;  3MI9 B;  2ZPG B;  4UN0 A;  4F6U B;  4TTH A;  4EOM B;  4IMY B;  2JGZ B;  3B57 A;  2W2H A;  2DD5 B;  2IW8 B;  2WFY B;  4AI6 A;  4EOQ B;  5ACB A;  4HNV A;  2WIH B;  1W98 B;  2WPA B;  3BG9 A;  5EFQ B;  4NC6 A;  2CCI B;  2DME A;  4BCN D;  4JX6 A;  2PK2 A;  4BBS M;  4EC9 B;  1UGS B;  4OB3 B;  1JSU B;  4ROC A;  4JX5 A;  2DXC B;  3MY1 B;  3DDP B;  5BNJ B;  1OKV B;  2DXB B;  1N4M A;  2BKZ B;  3A8G B;  4EOS B;  5L2W B;  4Z6Y A;  1H24 B;  4EOJ B;  2ZPH B;  1JST B;  1OL2 B;  2ZZD B;  4BY7 X;  2X1N B;  1FIN B;  1P5E B;  3TNW B;  1OGU B;  2CYZ B;  4F7S B;  2UUE B;  4II5 B;  2LW4 A;  1H1S B;  1OL1 B;  5HBE B;  3QYG B;  5HBH B;  4YOS A;  5IF1 B;  3MY5 B;  3EOC B;  3QHW B;  5DQV A;  2C5N B;  2IW6 B;  2C6T B;  3EID B;  2BS2 A;  1GH6 B;  3BHV B;  3A8H B;  4BCM B;  1H27 B;  4CXA B;  2R7G A;  3X24 B;  1G3N C;  2G77 A;  1ENW A;  4AKG A;  1H1Q B;  2ZPF B;  4MFD A;  2C5V B;  3A8L B;  2V22 B;  2UZB B;  4CFX B;  1H28 B;  1V29 B;  4EOP B;  1JKW A;  5CYI B;  3M03 A;  4EOO B;  2G9X B;  4YOO A;  1AHJ B;  2ZPI B;  4BCP B;  1GUX B;  4AKH A;  2IW9 B;  2QFZ A;  2B9R A;  4CFW B;  1UGR B;  2QDJ A;  3TN8 B;  3HB9 A;  1OIU B;  3DJB A;  1UGQ B;  4AKI A;  5LQF B;  4F70 B;  4MIM A;  2C5O B;  4MFE A;  1O9K B;  4OB1 B;  1QMZ B;  4NST B;  2QF7 A;  2CZ0 B;  4OB0 B;  4YOZ A;  4FM4 B;  4EOI B;  3TW6 A;  3DTO A;  4CFM B;  5HBJ B;  4CFV B;  4FX3 B;  3HBL A;  4OR5 B;  4F7J B;  2BPM B;  2ZPB B;  4HLQ A;  4CFU D;  3BLH B;  3EJ1 B;  4YC3 B;  1BU2 A;  4BBR M;  4EC8 B;  2EUF A;  2QQ8 A;  1E7P A;  3KHI A;  1OIY B;  1C9B A;  2CZ7 B;  3H4C A;  3DOG B;  2W99 A;  4BCK B;  4EOL B;  2PHG A;  1UNL D;  1URC B;  3QZ9 B;  5IHY A;  5HQ0 B;  2W9F A;  3HO8 A;  4ZGD B;  2QGS A;  2BS3 A;  3QWL A;  3TNH B;  3QXE B;  5HVY B;  3VYH B;  2PK9 B;  3BHT B;  2UZL B;  1KXU A;  4ZGJ B;  4BCQ D;  1OKW B;  4BCI B;  4EON B;  2UZD B;  3RGF B;  5ICP B;  4BXX X;  4G6L B;  5LMK B;  2W96 A;  4ZGE B;  4F7L B;  3PO3 S;  3BG5 A;  1AIS B;  2ZPE B;  4HNT A;  2BS4 A;  1TD6 A;  4BCN B;  5IDN B;  3QZ5 B;  3LQ5 B;  4ELL A;  3POM A;  2WMB B;  5FGK B;  2PMI B;  3G33 B;  4EOR B;  1H4L D;  3VYG B;  1JOW A;  4JX4 A;  4BCO B;  1UNH D;  3DL1 A;  3O0G D;  3X20 B;  2CZ1 B;  2C4G B;  1OI9 B;  3TW7 A;  1TFB A;  4CFU B;  3TNI B;  2UZE B;  2ZCF B;  4HNU A;  1H26 B;  3HZJ A;  5IDP B;  3GTM S;  3BLR B;  2C5X B;  3BLQ B;  2D0Q B;  1UGP B;  3DDQ B;  1E9H B;  4BCF B;  4BCG B;  2IN3 A;  3MIA B;  1H1P B;  1IRE B;  3X28 B;  2CCH B;  2DD4 B;  1F5Q B;  3HHT B;  3VKG A;  3QYE A;  2CJM B;  3F5X B;  2AHJ B;  4BCJ B;  2WIP B; 
#chains in the Genus database with same CATH homology
 2CZ6 B;  3WVD B;  1AHJ B;  1QLB A;  2ZPI B;  4JX6 A;  4BBS M;  4ELJ A;  1UGS B;  4OB3 B;  4AKH A;  4JX5 A;  4ZGJ B;  2QFZ A;  2DXC B;  1UGR B;  2QDJ A;  3A8M B;  2DXB B;  3QYH B;  2DPP B;  3A8G B;  3HB9 A;  3A8O B;  3BG3 A;  4Z6Y A;  4ZGE B;  2WJ9 A;  4QSH A;  2ZPH B;  1UGQ B;  3BG5 A;  4HL4 A;  4AKI A;  2ZPE B;  4HNT A;  3QYB A;  2ZZD B;  4LOC A;  4MIM A;  4MFE A;  2BS4 A;  4OB1 B;  2QDY B;  2QF7 A;  3QZ5 B;  2CZ0 B;  1FKM A;  4OB0 B;  4FM4 B;  3X25 B;  3TW6 A;  2CYZ B;  3VYG B;  4JX4 A;  3HBL A;  2ZPB B;  4HLQ A;  3DL1 A;  3QYG B;  3X20 B;  5EJC A;  2CZ1 B;  3X26 B;  2KR6 A;  3TW7 A;  3WVE B;  4BBR M;  2ZCF B;  4HNU A;  3HZJ A;  4OB2 B;  2BS2 A;  2D0Q B;  2KMG A;  4M6V A;  3A8H B;  1UGP B;  2QQ8 A;  3VKH A;  1E7P A;  3KHI A;  2ZPG B;  3X24 B;  1IRE B;  3X28 B;  2CZ7 B;  3H4C A;  2G77 A;  2DD5 B;  2DD4 B;  4AKG A;  2ZPF B;  3HHT B;  4AI6 A;  3VKG A;  4MFD A;  3A8L B;  4HNV A;  3QZ9 B;  3QYE A;  3HO8 A;  3BG9 A;  4ZGD B;  2BS3 A;  3QWL A;  4NC6 A;  1V29 B;  3QXE B;  2AHJ B;  3VYH B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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