2KVEA

C-terminal domain of mesencephalic astrocyte-derived neurotrophic factor (manf)
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
65
structure length
65
Chain Sequence
MGKYDKQIDLSTVDLKKLRVKELKKILDDWGETCKGCAEKSDYIRKINELMPKYAPKAASARTDL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) Has a Unique Mechanism to Rescue Apoptotic Neurons
pubmed doi rcsb
molecule tags Hormone
source organism Homo sapiens
molecule keywords Mesencephalic astrocyte-derived neurotrophic factor
total genus 11
structure length 65
sequence length 65
ec nomenclature
pdb deposition date 2010-03-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.720.30 Mainly Alpha Orthogonal Bundle Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 SAP domain 2kveA00
1JEQA 1V66A 4UZWA 2KVDA 2RNOA 2KW9A 2WQGA 4BITA 1ZBHA 2JVWA 2KVEA 1JJRA 2KVUA 1H1JS 2RNNA
chains in the Genus database with same CATH superfamily
1JEQA 3FLGA 3LLRA 1Y02A 2DK4A 4BITA 1H9EA 1A8VA 4UZWA 2KVDA 2RNOA 2KW9A 1ZS9A 1E7DA 1GKUB 2MPHA 1E7LA 2WQGA 3L0OA 3QKJA 1JEIA 2KVEA 2LD7A 2QNCA 1EN7A 2A8VA 2KFVA 1YNSA 2G80A 1ZBHA 2W51A 1GL9B 2ODCI 1H9FA 1A62A 2RNNA 1GJJA 1V66A 2LC3A 1KHCA 2QNFA 5CIUA 1A63A 2JVWA 2ODGC 1JJRA 2KVUA 1H1JS 2HJQA
chains in the Genus database with same CATH topology
1JEQA 1V66A 4UZWA 2KVDA 2RNOA 2KW9A 2WQGA 4BITA 1ZBHA 2JVWA 2KVEA 1JJRA 2KVUA 1H1JS 2RNNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JEQ A;  1V66 A;  4UZW A;  2KVD A;  2RNO A;  2KW9 A;  2WQG A;  4BIT A;  1ZBH A;  2JVW A;  2KVE A;  1JJR A;  2KVU A;  1H1J S;  2RNN A; 
#chains in the Genus database with same CATH topology
 1JEQ A;  3FLG A;  3LLR A;  1Y02 A;  2DK4 A;  4BIT A;  1H9E A;  1A8V A;  4UZW A;  2KVD A;  2RNO A;  2KW9 A;  1ZS9 A;  1E7D A;  1GKU B;  2MPH A;  1E7L A;  2WQG A;  3L0O A;  3QKJ A;  1JEI A;  2KVE A;  2LD7 A;  2QNC A;  1EN7 A;  2A8V A;  2KFV A;  1YNS A;  2G80 A;  1ZBH A;  2W51 A;  1GL9 B;  2ODC I;  1H9F A;  1A62 A;  2RNN A;  1GJJ A;  1V66 A;  2LC3 A;  1KHC A;  2QNF A;  5CIU A;  1A63 A;  2JVW A;  2ODG C;  1JJR A;  2KVU A;  1H1J S;  2HJQ A; 
#chains in the Genus database with same CATH homology
 1JEQ A;  1V66 A;  4UZW A;  2KVD A;  2RNO A;  2KW9 A;  2WQG A;  4BIT A;  1ZBH A;  2JVW A;  2KVE A;  1JJR A;  2KVU A;  1H1J S;  2RNN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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