2KVEA

C-terminal domain of mesencephalic astrocyte-derived neurotrophic factor (manf)
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
65
structure length
65
Chain Sequence
MGKYDKQIDLSTVDLKKLRVKELKKILDDWGETCKGCAEKSDYIRKINELMPKYAPKAASARTDL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hormone
molecule keywords Mesencephalic astrocyte-derived neurotrophic factor
publication title Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) Has a Unique Mechanism to Rescue Apoptotic Neurons
pubmed doi rcsb
source organism Homo sapiens
total genus 11
structure length 65
sequence length 65
ec nomenclature
pdb deposition date 2010-03-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.720.30 Mainly Alpha Orthogonal Bundle Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 SAP domain 2kveA00
2WQGA 1JJRA 2JVWA 2KVEA 4BITA 2KVDA 2RNNA 2KW9A 1ZBHA 1JEQA 2KVUA 1V66A 4UZWA 1H1JS 2RNOA
chains in the Genus database with same CATH superfamily
1KHCA 2JVWA 2QNFA 1GL9B 2MPHA 2A8VA 1ZBHA 3LLRA 1YNSA 1V66A 3QKJA 2RNOA 2HJQA 1JJRA 5CIUA 1JEIA 2KVEA 1E7DA 4BITA 1A62A 2ODGC 2KW9A 3L0OA 3FLGA 2KVUA 1GJJA 1H9FA 2W51A 2WQGA 2ODCI 2G80A 1EN7A 1A63A 1E7LA 1A8VA 1JEQA 2KFVA 4UZWA 1Y02A 1H1JS 2LD7A 2QNCA 1GKUB 1ZS9A 2KVDA 2RNNA 1H9EA 2LC3A 2DK4A
chains in the Genus database with same CATH topology
2WQGA 1JJRA 2JVWA 2KVEA 4BITA 2KVDA 2RNNA 2KW9A 1ZBHA 1JEQA 2KVUA 1V66A 4UZWA 1H1JS 2RNOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WQG A;  1JJR A;  2JVW A;  2KVE A;  4BIT A;  2KVD A;  2RNN A;  2KW9 A;  1ZBH A;  1JEQ A;  2KVU A;  1V66 A;  4UZW A;  1H1J S;  2RNO A; 
#chains in the Genus database with same CATH topology
 1KHC A;  2JVW A;  2QNF A;  1GL9 B;  2MPH A;  2A8V A;  1ZBH A;  3LLR A;  1YNS A;  1V66 A;  3QKJ A;  2RNO A;  2HJQ A;  1JJR A;  5CIU A;  1JEI A;  2KVE A;  1E7D A;  4BIT A;  1A62 A;  2ODG C;  2KW9 A;  3L0O A;  3FLG A;  2KVU A;  1GJJ A;  1H9F A;  2W51 A;  2WQG A;  2ODC I;  2G80 A;  1EN7 A;  1A63 A;  1E7L A;  1A8V A;  1JEQ A;  2KFV A;  4UZW A;  1Y02 A;  1H1J S;  2LD7 A;  2QNC A;  1GKU B;  1ZS9 A;  2KVD A;  2RNN A;  1H9E A;  2LC3 A;  2DK4 A; 
#chains in the Genus database with same CATH homology
 2WQG A;  1JJR A;  2JVW A;  2KVE A;  4BIT A;  2KVD A;  2RNN A;  2KW9 A;  1ZBH A;  1JEQ A;  2KVU A;  1V66 A;  4UZW A;  1H1J S;  2RNO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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