2L27A

Nmr structure of the ecd1 of crf-r1 in complex with a peptide agonist
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
84
structure length
84
Chain Sequence
LQDQHCESLSLASNISGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Membrane protein, peptide binding protein
molecule keywords Corticotropin-releasing factor receptor 1
publication title NMR structure of the first extracellular domain of corticotropin-releasing factor receptor 1 (ECD1-CRF-R1) complexed with a high affinity agonist.
pubmed doi rcsb
source organism Homo sapiens
total genus 13
structure length 84
sequence length 84
ec nomenclature
pdb deposition date 2010-08-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02793 HRM Hormone receptor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.1240.10 Few Secondary Structures Irregular Hormone receptor fold GPCR, family 2, extracellular hormone receptor domain 2l27A00
4HJ0A 3IOLA 4LF3C 3C4MA 3H3GA 3N7RA 5II0A 2JODA 2QKHA 2L27A 3L2JA 3EHSA 3C59A 4DLQA 3N7SA 3AQFB 2JNCA 2XDGA 3N7PA 1U34A 3C5TA 4ERSA 4ZGMA 4DLOA 3EHTA 3EHUA 2JNDA
chains in the Genus database with same CATH superfamily
4HJ0A 3IOLA 4LF3C 3C4MA 3H3GA 3N7RA 5II0A 2JODA 2QKHA 2L27A 3L2JA 3EHSA 3C59A 4DLQA 3N7SA 3AQFB 2JNCA 2XDGA 3N7PA 1U34A 3C5TA 4ERSA 4ZGMA 4DLOA 3EHTA 3EHUA 2JNDA
chains in the Genus database with same CATH topology
4HJ0A 3IOLA 4LF3C 3C4MA 3H3GA 3N7RA 5II0A 2JODA 2QKHA 2L27A 3L2JA 3EHSA 3C59A 4DLQA 3N7SA 3AQFB 2JNCA 2XDGA 3N7PA 1U34A 3C5TA 4ERSA 4ZGMA 4DLOA 3EHTA 3EHUA 2JNDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HJ0 A;  3IOL A;  4LF3 C;  3C4M A;  3H3G A;  3N7R A;  5II0 A;  2JOD A;  2QKH A;  2L27 A;  3L2J A;  3EHS A;  3C59 A;  4DLQ A;  3N7S A;  3AQF B;  2JNC A;  2XDG A;  3N7P A;  1U34 A;  3C5T A;  4ERS A;  4ZGM A;  4DLO A;  3EHT A;  3EHU A;  2JND A; 
#chains in the Genus database with same CATH topology
 4HJ0 A;  3IOL A;  4LF3 C;  3C4M A;  3H3G A;  3N7R A;  5II0 A;  2JOD A;  2QKH A;  2L27 A;  3L2J A;  3EHS A;  3C59 A;  4DLQ A;  3N7S A;  3AQF B;  2JNC A;  2XDG A;  3N7P A;  1U34 A;  3C5T A;  4ERS A;  4ZGM A;  4DLO A;  3EHT A;  3EHU A;  2JND A; 
#chains in the Genus database with same CATH homology
 4HJ0 A;  3IOL A;  4LF3 C;  3C4M A;  3H3G A;  3N7R A;  5II0 A;  2JOD A;  2QKH A;  2L27 A;  3L2J A;  3EHS A;  3C59 A;  4DLQ A;  3N7S A;  3AQF B;  2JNC A;  2XDG A;  3N7P A;  1U34 A;  3C5T A;  4ERS A;  4ZGM A;  4DLO A;  3EHT A;  3EHU A;  2JND A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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