2L4ZA

Nmr structure of fusion of ctip (641-685) to lmo4-lim1 (18-82)
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
121
structure length
121
Chain Sequence
SLQNNQDVSFENIQWSIDPGADLSQYKMDVTVIDTKDGSQSKLGGGGSGGHMGSGGLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSSCQAQLGDIGTSSYTKSGMILCRNDYIRLFG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis of the Interaction of the Breast Cancer Oncogene LMO4 with the Tumour Suppressor CtIP/RBBP8.
pubmed doi rcsb
molecule tags Hydrolase, metal binding protein
source organism Homo sapiens, undefined
molecule keywords DNA endonuclease RBBP8, LIM domain transcription factor LMO4
total genus 19
structure length 121
sequence length 121
ec nomenclature
pdb deposition date 2010-10-22
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.110.10 Mainly Beta Ribbon Cysteine Rich Protein Cysteine Rich Protein 2l4zA01
2O13A 1WIGA 2D8ZA 1X4LA 2D8XA 2XJYA 4HI8B 1RUTX 1U5SB 2DLOA 2JTNA 1X63A 2DARA 1X6AA 2L4ZA 1X62A 2LXDA 3F6QB 2O10A 2D8YA 4JCJA 1J2OA 2MBVA 3MMKA 2CO8A 2L6YB 1X64A 2CU8A 1NYPA 2CUQA 2LZUA 1G47A 2EHEA 1CXXA 2XJZA 2IYBE 1WYHA 2DJ7A 2CURA 1X61A 1B8TA 1IMLA 1IBIA 2CUPA 4HI9B 3IXEB 1X3HA 2CORA 1QLIA 1M3VA 2XQNT 2MIUA 1V6GA 2YPAC 1A7IA 2EGQA 1CTLA 4KFZA 2DFYC 2L6ZC 1X68A 2KBXB
chains in the Genus database with same CATH superfamily
5LKXA 1X4LA 2D8XA 4HI8B 1RUTX 5FY7A 5FXVA 2JTNA 4ASKA 2DARA 1X6AA 2L4ZA 4EZHA 3F6QB 5FXZA 2CO8A 3ZPOA 1X64A 2CU8A 4EZ4A 2LZUA 2DJ7A 1X61A 1IMLA 1IBIA 4HI9B 2XUEA 2CORA 4KFZA 3NIKA 4UF0B 2KBXB 1WIGA 2D8ZA 3NILA 2DLOA 5A1LA 5LKZA 1X62A 3NISA 4UF0A 3MMKA 2CUQA 1G47A 2EHEA 1CXXA 3NIMA 2CUPA 1M3VA 3NINA 3NIJA 2DFYC 1X63A 5LKUA 3NIHA 5LKTA 1J2OA 3AVRA 2MBVA 2L6YB 5FYMA 5FY0A 2IYBE 2CURA 1B8TA 1QLIA 2MIUA 2YPAC 1A7IA 1CTLA 2L6ZC 2O13A 4EYUA 2XJYA 1U5SB 5FY1A 3AVSA 2LXDA 2O10A 2D8YA 4JCJA 5FXXA 5FXWA 1NYPA 5FP3A 2XJZA 1WYHA 4BHWA 3IXEB 3ZLIA 1X3HA 2XQNT 1V6GA 2EGQA 1X68A
chains in the Genus database with same CATH topology
5LKXA 1X4LA 2D8XA 4HI8B 1RUTX 5FY7A 5FXVA 2JTNA 4ASKA 2DARA 1X6AA 2L4ZA 4EZHA 3F6QB 5FXZA 2CO8A 3ZPOA 1X64A 2CU8A 4EZ4A 2LZUA 2DJ7A 1X61A 1IMLA 1IBIA 4HI9B 2XUEA 2CORA 4KFZA 3NIKA 4UF0B 2KBXB 1WIGA 2D8ZA 3NILA 2DLOA 5A1LA 5LKZA 1X62A 3NISA 4UF0A 3MMKA 2CUQA 1G47A 2EHEA 1CXXA 3NIMA 2CUPA 1M3VA 3NINA 3NIJA 2DFYC 1X63A 5LKUA 3NIHA 5LKTA 1J2OA 3AVRA 2MBVA 2L6YB 5FYMA 5FY0A 2IYBE 2CURA 1B8TA 1QLIA 2MIUA 2YPAC 1A7IA 1CTLA 2L6ZC 2O13A 4EYUA 2XJYA 1U5SB 5FY1A 3AVSA 2LXDA 2O10A 2D8YA 4JCJA 5FXXA 5FXWA 1NYPA 5FP3A 2XJZA 1WYHA 4BHWA 3IXEB 3ZLIA 1X3HA 2XQNT 1V6GA 2EGQA 1X68A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2O13 A;  1WIG A;  2D8Z A;  1X4L A;  2D8X A;  2XJY A;  4HI8 B;  1RUT X;  1U5S B;  2DLO A;  2JTN A;  1X63 A;  2DAR A;  1X6A A;  2L4Z A;  1X62 A;  2LXD A;  3F6Q B;  2O10 A;  2D8Y A;  4JCJ A;  1J2O A;  2MBV A;  3MMK A;  2CO8 A;  2L6Y B;  1X64 A;  2CU8 A;  1NYP A;  2CUQ A;  2LZU A;  1G47 A;  2EHE A;  1CXX A;  2XJZ A;  2IYB E;  1WYH A;  2DJ7 A;  2CUR A;  1X61 A;  1B8T A;  1IML A;  1IBI A;  2CUP A;  4HI9 B;  3IXE B;  1X3H A;  2COR A;  1QLI A;  1M3V A;  2XQN T;  2MIU A;  1V6G A;  2YPA C;  1A7I A;  2EGQ A;  1CTL A;  4KFZ A;  2DFY C;  2L6Z C;  1X68 A;  2KBX B; 
#chains in the Genus database with same CATH topology
 5LKX A;  1X4L A;  2D8X A;  4HI8 B;  1RUT X;  5FY7 A;  5FXV A;  2JTN A;  4ASK A;  2DAR A;  1X6A A;  2L4Z A;  4EZH A;  3F6Q B;  5FXZ A;  2CO8 A;  3ZPO A;  1X64 A;  2CU8 A;  4EZ4 A;  2LZU A;  2DJ7 A;  1X61 A;  1IML A;  1IBI A;  4HI9 B;  2XUE A;  2COR A;  4KFZ A;  3NIK A;  4UF0 B;  2KBX B;  1WIG A;  2D8Z A;  3NIL A;  2DLO A;  5A1L A;  5LKZ A;  1X62 A;  3NIS A;  4UF0 A;  3MMK A;  2CUQ A;  1G47 A;  2EHE A;  1CXX A;  3NIM A;  2CUP A;  1M3V A;  3NIN A;  3NIJ A;  2DFY C;  1X63 A;  5LKU A;  3NIH A;  5LKT A;  1J2O A;  3AVR A;  2MBV A;  2L6Y B;  5FYM A;  5FY0 A;  2IYB E;  2CUR A;  1B8T A;  1QLI A;  2MIU A;  2YPA C;  1A7I A;  1CTL A;  2L6Z C;  2O13 A;  4EYU A;  2XJY A;  1U5S B;  5FY1 A;  3AVS A;  2LXD A;  2O10 A;  2D8Y A;  4JCJ A;  5FXX A;  5FXW A;  1NYP A;  5FP3 A;  2XJZ A;  1WYH A;  4BHW A;  3IXE B;  3ZLI A;  1X3H A;  2XQN T;  1V6G A;  2EGQ A;  1X68 A; 
#chains in the Genus database with same CATH homology
 5LKX A;  1X4L A;  2D8X A;  4HI8 B;  1RUT X;  5FY7 A;  5FXV A;  2JTN A;  4ASK A;  2DAR A;  1X6A A;  2L4Z A;  4EZH A;  3F6Q B;  5FXZ A;  2CO8 A;  3ZPO A;  1X64 A;  2CU8 A;  4EZ4 A;  2LZU A;  2DJ7 A;  1X61 A;  1IML A;  1IBI A;  4HI9 B;  2XUE A;  2COR A;  4KFZ A;  3NIK A;  4UF0 B;  2KBX B;  1WIG A;  2D8Z A;  3NIL A;  2DLO A;  5A1L A;  5LKZ A;  1X62 A;  3NIS A;  4UF0 A;  3MMK A;  2CUQ A;  1G47 A;  2EHE A;  1CXX A;  3NIM A;  2CUP A;  1M3V A;  3NIN A;  3NIJ A;  2DFY C;  1X63 A;  5LKU A;  3NIH A;  5LKT A;  1J2O A;  3AVR A;  2MBV A;  2L6Y B;  5FYM A;  5FY0 A;  2IYB E;  2CUR A;  1B8T A;  1QLI A;  2MIU A;  2YPA C;  1A7I A;  1CTL A;  2L6Z C;  2O13 A;  4EYU A;  2XJY A;  1U5S B;  5FY1 A;  3AVS A;  2LXD A;  2O10 A;  2D8Y A;  4JCJ A;  5FXX A;  5FXW A;  1NYP A;  5FP3 A;  2XJZ A;  1WYH A;  4BHW A;  3IXE B;  3ZLI A;  1X3H A;  2XQN T;  1V6G A;  2EGQ A;  1X68 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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