2L6UA

Solution nmr structure of med25(391-543) comprising the activator-interacting domain (acid) of human mediator subuniti 25. northeast structural genomics consortium target hr6188a
Total Genus 34
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
163
structure length
163
Chain Sequence
MGHHHHHHSHGQQSVSNKLLAWSGVLEWQEKPKPASVDANTKLTRSLPCQVYVNHGENLKTEQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFHFTNKDLESLKGLYRIMGNGFAGCVHFPHTAPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNGIRQVITN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transcription
molecule keywords Mediator complex subunit MED25
publication title Solution NMR structure of MED25(391-543) comprising the activator-interacting domain (ACID) of human mediator subunit 25.
pubmed doi rcsb
source organism Homo sapiens
total genus 34
structure length 163
sequence length 163
ec nomenclature
pdb deposition date 2010-11-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.290.30 Mainly Beta Beta Barrel Ku70; Chain: A; Domain 2 Ku70; Chain: A; Domain 2 2l6uA00
2KY6A 2L6UA 2XNFA 2L23A
chains in the Genus database with same CATH superfamily
2L6UA 1JEQA 1JEQB 1JEYA 1JEYB 2XNFA 2L23A 2RT5A 3TIXB 2KY6A 1OW1A
chains in the Genus database with same CATH topology
2L6UA 1JEQA 1JEQB 1JEYA 1JEYB 2XNFA 2L23A 2RT5A 3TIXB 2KY6A 1OW1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KY6 A;  2L6U A;  2XNF A;  2L23 A; 
#chains in the Genus database with same CATH topology
 2L6U A;  1JEQ A;  1JEQ B;  1JEY A;  1JEY B;  2XNF A;  2L23 A;  2RT5 A;  3TIX B;  2KY6 A;  1OW1 A; 
#chains in the Genus database with same CATH homology
 2L6U A;  1JEQ A;  1JEQ B;  1JEY A;  1JEY B;  2XNF A;  2L23 A;  2RT5 A;  3TIX B;  2KY6 A;  1OW1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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