2L72A

Solution structure and dynamics of adf from toxoplasma gondii (tgadf)
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
118
structure length
118
Chain Sequence
MASGMGVDENCVARFNELKIRKTVKWIVFKIENTKIVVEKDGKGNADEFRGALPANDCRFGVYDCGNKIQFVLWCPDNAPVKPRMTYASSKDALLKKLDGATAVALEAHEMGDLAPLA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure and dynamics of ADF from Toxoplasma gondii
pubmed doi rcsb
source organism Toxoplasma gondii
molecule tags Protein binding
molecule keywords Actin depolymerizing factor, putative
total genus 23
structure length 118
sequence length 118
ec nomenclature
pdb deposition date 2010-12-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00241 Cofilin_ADF Cofilin/tropomyosin-type actin-binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.20.10 Alpha Beta 3-Layer(aba) Sandwich Severin Severin 2l72A00
1VKKA 1H1VG 1M2VA 3CJCG 1D0NA 1PD1A 3DAWB 1WM4A 5KYWA 1NMDG 1JHWA 1MDUA 2NUTA 3FFKA 1M4JA 2VILA 1HQZ1 1X67A 3EGDA 1C0GS 3A5NS 2KVKA 1WNJA 1DEJS 2FH3A 4KEFA 1PD0A 3EH1A 4CBXG 1NLVG 1AHQA 4Z94G 1EQYS 3CIPG 5KYYA 5IVUA 1UDMA 5FAEA 3A5MS 1P8XA 2I2QA 2FH4A 3Q2BA 1QPVA 2XF1A 3FFNA 1ESVS 1TVJA 3A5OS 3EG9A 1AK7A 4JD2H 1YVNG 1NPHA 4CBWG 1AK6A 5KYYB 2NUPA 5L6WC 4LIZA 3CI5G 1M2VB 1F7SA 1RGIG 4PKHB 1V6FA 3A5LS 4PKIG 1C0FS 1NM1G 1Q8GA 3L50A 2NUTB 4BEX1 3EGXA 1Q8XA 2LXXA 5FAFA 3EG9B 2MP4A 5KYUB 2FF6G 2QTVA 3EFOB 1P8ZG 1T2LA 1M2OA 5HVKD 1YAGG 2FH1A 1D4XG 1T3XA 5DD2A 2LJ8A 1CNUA 3EGDB 2HD7A 3TU5B 4PKGG 2NUPB 3EFOA 2FH2A 2VIKA 1VFQA 3EH2A 3FG7A 1SVYA 1CFYA 2W0IA 3CJBG 5KYXB 4KEEA 2LLFA 1T3YA 5HVKB 3FG6A 2D8BA 5KYNA 1TMWA 5A1MA 1KCQA 2MV2A 1T44G 5KYWB 2L72A 3EGXB 2FF3A 1J72A 1SVRA 2FGHA 4S10C 1PCXA 4KEDA 2XFAA 5KYXA 1WFSA 1SVQA 1COFA 4CBUG 2VACA 5KYUA 2MOTA
chains in the Genus database with same CATH superfamily
1VKKA 1H1VG 1M2VA 3CJCG 1D0NA 1PD1A 3DAWB 1WM4A 5KYWA 1NMDG 1JHWA 1MDUA 2NUTA 3FFKA 1M4JA 2VILA 1HQZ1 1X67A 3EGDA 1C0GS 3A5NS 2KVKA 1WNJA 1DEJS 2FH3A 4KEFA 1PD0A 3EH1A 4CBXG 1NLVG 1AHQA 4Z94G 1EQYS 3CIPG 5KYYA 5IVUA 1UDMA 5FAEA 3A5MS 1P8XA 2I2QA 2FH4A 3Q2BA 1QPVA 2XF1A 3FFNA 1ESVS 1TVJA 3A5OS 3EG9A 1AK7A 4JD2H 1YVNG 1NPHA 4CBWG 1AK6A 5KYYB 2NUPA 5L6WC 4LIZA 3CI5G 3DA7A 1M2VB 1F7SA 1RGIG 4PKHB 1V6FA 3A5LS 4PKIG 1C0FS 1NM1G 1Q8GA 3L50A 2NUTB 4BEX1 3EGXA 1Q8XA 2LXXA 5FAFA 3EG9B 2MP4A 5KYUB 2FF6G 2QTVA 3EFOB 1P8ZG 1T2LA 1M2OA 5HVKD 1YAGG 2FH1A 1D4XG 1T3XA 5DD2A 2LJ8A 1CNUA 3EGDB 2HD7A 3TU5B 4PKGG 2NUPB 3EFOA 2FH2A 2VIKA 1VFQA 3EH2A 3FG7A 1SVYA 1CFYA 2W0IA 3CJBG 5KYXB 4KEEA 2LLFA 1T3YA 5HVKB 3FG6A 2D8BA 5KYNA 1TMWA 5A1MA 1KCQA 2MV2A 1T44G 5KYWB 2L72A 3EGXB 2FF3A 1J72A 1SVRA 2FGHA 4S10C 1PCXA 4KEDA 2XFAA 5KYXA 1WFSA 1SVQA 1COFA 4CBUG 2VACA 5KYUA 2MOTA
chains in the Genus database with same CATH topology
1VKKA 1H1VG 1M2VA 3CJCG 1D0NA 1PD1A 3DAWB 1WM4A 5KYWA 1NMDG 1JHWA 1MDUA 2NUTA 3FFKA 1M4JA 2VILA 1HQZ1 1X67A 3EGDA 1C0GS 3A5NS 2KVKA 1WNJA 1DEJS 2FH3A 4KEFA 1PD0A 3EH1A 4CBXG 1NLVG 1AHQA 4Z94G 1EQYS 3CIPG 5KYYA 5IVUA 1UDMA 5FAEA 3A5MS 1P8XA 2I2QA 2FH4A 3Q2BA 1QPVA 2XF1A 3FFNA 1ESVS 1TVJA 3A5OS 3EG9A 1AK7A 4JD2H 1YVNG 1NPHA 4CBWG 1AK6A 5KYYB 2NUPA 5L6WC 4LIZA 3CI5G 3DA7A 1M2VB 1F7SA 1RGIG 4PKHB 1V6FA 3A5LS 4PKIG 1C0FS 1NM1G 1Q8GA 3L50A 2NUTB 4BEX1 3EGXA 1Q8XA 2LXXA 5FAFA 3EG9B 2MP4A 5KYUB 2FF6G 2QTVA 3EFOB 1P8ZG 1T2LA 1M2OA 5HVKD 1YAGG 2FH1A 1D4XG 1T3XA 5DD2A 2LJ8A 1CNUA 3EGDB 2HD7A 3TU5B 4PKGG 2NUPB 3EFOA 2FH2A 2VIKA 1VFQA 3EH2A 3FG7A 1SVYA 1CFYA 2W0IA 3CJBG 5KYXB 4KEEA 2LLFA 1T3YA 5HVKB 3FG6A 2D8BA 5KYNA 1TMWA 5A1MA 1KCQA 2MV2A 1T44G 5KYWB 2L72A 3EGXB 2FF3A 1J72A 1SVRA 2FGHA 4S10C 1PCXA 4KEDA 2XFAA 5KYXA 1WFSA 1SVQA 1COFA 4CBUG 2VACA 5KYUA 2MOTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VKK A;  1H1V G;  1M2V A;  3CJC G;  1D0N A;  1PD1 A;  3DAW B;  1WM4 A;  5KYW A;  1NMD G;  1JHW A;  1MDU A;  2NUT A;  3FFK A;  1M4J A;  2VIL A;  1HQZ 1;  1X67 A;  3EGD A;  1C0G S;  3A5N S;  2KVK A;  1WNJ A;  1DEJ S;  2FH3 A;  4KEF A;  1PD0 A;  3EH1 A;  4CBX G;  1NLV G;  1AHQ A;  4Z94 G;  1EQY S;  3CIP G;  5KYY A;  5IVU A;  1UDM A;  5FAE A;  3A5M S;  1P8X A;  2I2Q A;  2FH4 A;  3Q2B A;  1QPV A;  2XF1 A;  3FFN A;  1ESV S;  1TVJ A;  3A5O S;  3EG9 A;  1AK7 A;  4JD2 H;  1YVN G;  1NPH A;  4CBW G;  1AK6 A;  5KYY B;  2NUP A;  5L6W C;  4LIZ A;  3CI5 G;  1M2V B;  1F7S A;  1RGI G;  4PKH B;  1V6F A;  3A5L S;  4PKI G;  1C0F S;  1NM1 G;  1Q8G A;  3L50 A;  2NUT B;  4BEX 1;  3EGX A;  1Q8X A;  2LXX A;  5FAF A;  3EG9 B;  2MP4 A;  5KYU B;  2FF6 G;  2QTV A;  3EFO B;  1P8Z G;  1T2L A;  1M2O A;  5HVK D;  1YAG G;  2FH1 A;  1D4X G;  1T3X A;  5DD2 A;  2LJ8 A;  1CNU A;  3EGD B;  2HD7 A;  3TU5 B;  4PKG G;  2NUP B;  3EFO A;  2FH2 A;  2VIK A;  1VFQ A;  3EH2 A;  3FG7 A;  1SVY A;  1CFY A;  2W0I A;  3CJB G;  5KYX B;  4KEE A;  2LLF A;  1T3Y A;  5HVK B;  3FG6 A;  2D8B A;  5KYN A;  1TMW A;  5A1M A;  1KCQ A;  2MV2 A;  1T44 G;  5KYW B;  2L72 A;  3EGX B;  2FF3 A;  1J72 A;  1SVR A;  2FGH A;  4S10 C;  1PCX A;  4KED A;  2XFA A;  5KYX A;  1WFS A;  1SVQ A;  1COF A;  4CBU G;  2VAC A;  5KYU A;  2MOT A; 
#chains in the Genus database with same CATH topology
 1VKK A;  1H1V G;  1M2V A;  3CJC G;  1D0N A;  1PD1 A;  3DAW B;  1WM4 A;  5KYW A;  1NMD G;  1JHW A;  1MDU A;  2NUT A;  3FFK A;  1M4J A;  2VIL A;  1HQZ 1;  1X67 A;  3EGD A;  1C0G S;  3A5N S;  2KVK A;  1WNJ A;  1DEJ S;  2FH3 A;  4KEF A;  1PD0 A;  3EH1 A;  4CBX G;  1NLV G;  1AHQ A;  4Z94 G;  1EQY S;  3CIP G;  5KYY A;  5IVU A;  1UDM A;  5FAE A;  3A5M S;  1P8X A;  2I2Q A;  2FH4 A;  3Q2B A;  1QPV A;  2XF1 A;  3FFN A;  1ESV S;  1TVJ A;  3A5O S;  3EG9 A;  1AK7 A;  4JD2 H;  1YVN G;  1NPH A;  4CBW G;  1AK6 A;  5KYY B;  2NUP A;  5L6W C;  4LIZ A;  3CI5 G;  3DA7 A;  1M2V B;  1F7S A;  1RGI G;  4PKH B;  1V6F A;  3A5L S;  4PKI G;  1C0F S;  1NM1 G;  1Q8G A;  3L50 A;  2NUT B;  4BEX 1;  3EGX A;  1Q8X A;  2LXX A;  5FAF A;  3EG9 B;  2MP4 A;  5KYU B;  2FF6 G;  2QTV A;  3EFO B;  1P8Z G;  1T2L A;  1M2O A;  5HVK D;  1YAG G;  2FH1 A;  1D4X G;  1T3X A;  5DD2 A;  2LJ8 A;  1CNU A;  3EGD B;  2HD7 A;  3TU5 B;  4PKG G;  2NUP B;  3EFO A;  2FH2 A;  2VIK A;  1VFQ A;  3EH2 A;  3FG7 A;  1SVY A;  1CFY A;  2W0I A;  3CJB G;  5KYX B;  4KEE A;  2LLF A;  1T3Y A;  5HVK B;  3FG6 A;  2D8B A;  5KYN A;  1TMW A;  5A1M A;  1KCQ A;  2MV2 A;  1T44 G;  5KYW B;  2L72 A;  3EGX B;  2FF3 A;  1J72 A;  1SVR A;  2FGH A;  4S10 C;  1PCX A;  4KED A;  2XFA A;  5KYX A;  1WFS A;  1SVQ A;  1COF A;  4CBU G;  2VAC A;  5KYU A;  2MOT A; 
#chains in the Genus database with same CATH homology
 1VKK A;  1H1V G;  1M2V A;  3CJC G;  1D0N A;  1PD1 A;  3DAW B;  1WM4 A;  5KYW A;  1NMD G;  1JHW A;  1MDU A;  2NUT A;  3FFK A;  1M4J A;  2VIL A;  1HQZ 1;  1X67 A;  3EGD A;  1C0G S;  3A5N S;  2KVK A;  1WNJ A;  1DEJ S;  2FH3 A;  4KEF A;  1PD0 A;  3EH1 A;  4CBX G;  1NLV G;  1AHQ A;  4Z94 G;  1EQY S;  3CIP G;  5KYY A;  5IVU A;  1UDM A;  5FAE A;  3A5M S;  1P8X A;  2I2Q A;  2FH4 A;  3Q2B A;  1QPV A;  2XF1 A;  3FFN A;  1ESV S;  1TVJ A;  3A5O S;  3EG9 A;  1AK7 A;  4JD2 H;  1YVN G;  1NPH A;  4CBW G;  1AK6 A;  5KYY B;  2NUP A;  5L6W C;  4LIZ A;  3CI5 G;  3DA7 A;  1M2V B;  1F7S A;  1RGI G;  4PKH B;  1V6F A;  3A5L S;  4PKI G;  1C0F S;  1NM1 G;  1Q8G A;  3L50 A;  2NUT B;  4BEX 1;  3EGX A;  1Q8X A;  2LXX A;  5FAF A;  3EG9 B;  2MP4 A;  5KYU B;  2FF6 G;  2QTV A;  3EFO B;  1P8Z G;  1T2L A;  1M2O A;  5HVK D;  1YAG G;  2FH1 A;  1D4X G;  1T3X A;  5DD2 A;  2LJ8 A;  1CNU A;  3EGD B;  2HD7 A;  3TU5 B;  4PKG G;  2NUP B;  3EFO A;  2FH2 A;  2VIK A;  1VFQ A;  3EH2 A;  3FG7 A;  1SVY A;  1CFY A;  2W0I A;  3CJB G;  5KYX B;  4KEE A;  2LLF A;  1T3Y A;  5HVK B;  3FG6 A;  2D8B A;  5KYN A;  1TMW A;  5A1M A;  1KCQ A;  2MV2 A;  1T44 G;  5KYW B;  2L72 A;  3EGX B;  2FF3 A;  1J72 A;  1SVR A;  2FGH A;  4S10 C;  1PCX A;  4KED A;  2XFA A;  5KYX A;  1WFS A;  1SVQ A;  1COF A;  4CBU G;  2VAC A;  5KYU A;  2MOT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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