2LS7A

High definition solution structure of ped/pea-15 death effector domain
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
90
structure length
90
Chain Sequence
MAEYGTLLQDLTNNITLEDLEQLKSACKEDIPSEKSEEITTGSAWFSFLESHNKLDKDNLSYIEHIFEISRRPDLLTMVVDYRTRVLKIS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title High-definition NMR structure of PED/PEA-15 death effector domain reveals details of key polar side chain interactions.
pubmed doi rcsb
molecule tags Apoptosis
source organism Mus musculus
molecule keywords Astrocytic phosphoprotein PEA-15
total genus 29
structure length 90
sequence length 90
ec nomenclature
pdb deposition date 2012-04-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01335 DED Death effector domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 2ls7A00
4QOBA 1E41A 1FADA 2LS7A 2KM6A 3YGSP 1WH4A 2NSNA 2DBFA 3MOPK 1E3YA 2BBRA 2MS7A 2YVIA 1UCPA 3KATA 2D96A 2NAQA 4IZ7B 4DWNA 3CRDA 4D8OA 3J63A 4N1KA 1A1ZA 3EZQB 4E9MA 2MN4A 4N1JA 1CY5A 1NGRA 2P1HA 1DGNA 2N00A 2A9IA 1D2ZB 1DDFA 4UZ0A 3MOPG 4M9ZA 4EWIA 2O71A 2N97A 2DBDA 1Z6TA 2B1WA 2DBGA 4P4HI 4M9XA 3LQRA 2IB1A 4JQWA 1C15A 3MOPA 2N83A 2VGQA 4A2QA 3LQQA 3CL3A 2M5VA 2MPCA 2DO9A 3EZQA 2GF5A 2A5YB 4LWDA 2MS8A 4IZ5E 1WXPA 4F44A 2HM2Q 2G7RA 1YGOA 2LWEA 4P4HA 3QF2A 2YGSA 2N1FA 4F42A 2F1SA 1CWWA 4O9FA 2DBHA 2OF5H 4O9LA 2NZ7A 4ZBWA 4A2WA 2YU0A 2L6AA 2OF5A 2LWDA 4NQKA 1PN5A 4JUPA 3T6PA 2N80A 4O7QA 4N1LA 4RHWA 1D2ZA 4FH0A 3YGSC 2YQFA 1N3KA 4I16A 1A1WA 2BBZA 2N7ZA 4IZAB 2KN6A 1WMGA 4M9SA 2L9MA 1ICHA 2MB9A 3J6JA 4O6XA 4RHWE
chains in the Genus database with same CATH superfamily
4QOBA 1E41A 1FADA 2LS7A 2KM6A 3YGSP 1WH4A 2NSNA 2DBFA 3MOPK 1E3YA 2BBRA 2MS7A 2YVIA 1UCPA 3KATA 2XV9A 2D96A 2NAQA 4IZ7B 4DWNA 3CRDA 4D8OA 3J63A 4N1KA 1A1ZA 3EZQB 4E9MA 2MN4A 4N1JA 1CY5A 1NGRA 2P1HA 1DGNA 2N00A 2A9IA 1D2ZB 1DDFA 4UZ0A 3MOPG 4M9ZA 4EWIA 2O71A 2N97A 2DBDA 1Z6TA 2B1WA 2DBGA 4P4HI 4M9XA 3LQRA 2IB1A 4JQWA 1C15A 3MOPA 2N83A 2VGQA 4A2QA 3LQQA 3CL3A 2M5VA 2MPCA 2DO9A 3EZQA 2GF5A 2A5YB 4LWDA 2MS8A 4IZ5E 1WXPA 4F44A 2HM2Q 2G7RA 1YGOA 2LWEA 4P4HA 3QF2A 2YGSA 2N1FA 4F42A 2F1SA 1CWWA 4O9FA 2DBHA 2OF5H 4O9LA 2NZ7A 4ZBWA 4A2WA 2YU0A 2L6AA 2OF5A 2LWDA 4NQKA 1PN5A 4JUPA 3T6PA 2N80A 2MJMA 4O7QA 4N1LA 4RHWA 1D2ZA 4FH0A 3YGSC 2YQFA 1N3KA 4I16A 1A1WA 2BBZA 2N7ZA 4IZAB 2KN6A 1WMGA 4M9SA 2L9MA 1ICHA 2MB9A 3J6JA 4O6XA 4RHWE
chains in the Genus database with same CATH topology
4QOBA 1E41A 1FADA 2LS7A 2KM6A 3YGSP 1WH4A 2NSNA 2DBFA 3MOPK 1E3YA 2BBRA 2MS7A 2YVIA 1UCPA 3KATA 2XV9A 2D96A 2NAQA 4IZ7B 4DWNA 3CRDA 4D8OA 3J63A 4N1KA 1A1ZA 3EZQB 4E9MA 2MN4A 4N1JA 1CY5A 1NGRA 2P1HA 1DGNA 2N00A 2A9IA 1D2ZB 1DDFA 4UZ0A 3MOPG 4M9ZA 4EWIA 2O71A 2N97A 2DBDA 1Z6TA 2B1WA 2DBGA 4P4HI 4M9XA 3LQRA 2IB1A 4JQWA 1C15A 3MOPA 2N83A 2VGQA 4A2QA 3LQQA 3CL3A 2M5VA 2MPCA 2DO9A 3EZQA 2GF5A 2A5YB 4LWDA 2MS8A 4IZ5E 1WXPA 4F44A 2HM2Q 2G7RA 1YGOA 2LWEA 4P4HA 3QF2A 2YGSA 2N1FA 4F42A 2F1SA 1CWWA 4O9FA 2DBHA 2OF5H 4O9LA 2NZ7A 4ZBWA 4A2WA 2YU0A 2L6AA 2OF5A 2LWDA 4NQKA 1PN5A 4JUPA 3T6PA 2N80A 2MJMA 4O7QA 4N1LA 4RHWA 1D2ZA 4FH0A 3YGSC 2YQFA 1N3KA 4I16A 1A1WA 2BBZA 2N7ZA 4IZAB 2KN6A 1WMGA 4M9SA 2L9MA 1ICHA 2MB9A 3J6JA 4O6XA 4RHWE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4QOB A;  1E41 A;  1FAD A;  2LS7 A;  2KM6 A;  3YGS P;  1WH4 A;  2NSN A;  2DBF A;  3MOP K;  1E3Y A;  2BBR A;  2MS7 A;  2YVI A;  1UCP A;  3KAT A;  2D96 A;  2NAQ A;  4IZ7 B;  4DWN A;  3CRD A;  4D8O A;  3J63 A;  4N1K A;  1A1Z A;  3EZQ B;  4E9M A;  2MN4 A;  4N1J A;  1CY5 A;  1NGR A;  2P1H A;  1DGN A;  2N00 A;  2A9I A;  1D2Z B;  1DDF A;  4UZ0 A;  3MOP G;  4M9Z A;  4EWI A;  2O71 A;  2N97 A;  2DBD A;  1Z6T A;  2B1W A;  2DBG A;  4P4H I;  4M9X A;  3LQR A;  2IB1 A;  4JQW A;  1C15 A;  3MOP A;  2N83 A;  2VGQ A;  4A2Q A;  3LQQ A;  3CL3 A;  2M5V A;  2MPC A;  2DO9 A;  3EZQ A;  2GF5 A;  2A5Y B;  4LWD A;  2MS8 A;  4IZ5 E;  1WXP A;  4F44 A;  2HM2 Q;  2G7R A;  1YGO A;  2LWE A;  4P4H A;  3QF2 A;  2YGS A;  2N1F A;  4F42 A;  2F1S A;  1CWW A;  4O9F A;  2DBH A;  2OF5 H;  4O9L A;  2NZ7 A;  4ZBW A;  4A2W A;  2YU0 A;  2L6A A;  2OF5 A;  2LWD A;  4NQK A;  1PN5 A;  4JUP A;  3T6P A;  2N80 A;  4O7Q A;  4N1L A;  4RHW A;  1D2Z A;  4FH0 A;  3YGS C;  2YQF A;  1N3K A;  4I16 A;  1A1W A;  2BBZ A;  2N7Z A;  4IZA B;  2KN6 A;  1WMG A;  4M9S A;  2L9M A;  1ICH A;  2MB9 A;  3J6J A;  4O6X A;  4RHW E; 
#chains in the Genus database with same CATH topology
 4QOB A;  1E41 A;  1FAD A;  2LS7 A;  2KM6 A;  3YGS P;  1WH4 A;  2NSN A;  2DBF A;  3MOP K;  1E3Y A;  2BBR A;  2MS7 A;  2YVI A;  1UCP A;  3KAT A;  2XV9 A;  2D96 A;  2NAQ A;  4IZ7 B;  4DWN A;  3CRD A;  4D8O A;  3J63 A;  4N1K A;  1A1Z A;  3EZQ B;  4E9M A;  2MN4 A;  4N1J A;  1CY5 A;  1NGR A;  2P1H A;  1DGN A;  2N00 A;  2A9I A;  1D2Z B;  1DDF A;  4UZ0 A;  3MOP G;  4M9Z A;  4EWI A;  2O71 A;  2N97 A;  2DBD A;  1Z6T A;  2B1W A;  2DBG A;  4P4H I;  4M9X A;  3LQR A;  2IB1 A;  4JQW A;  1C15 A;  3MOP A;  2N83 A;  2VGQ A;  4A2Q A;  3LQQ A;  3CL3 A;  2M5V A;  2MPC A;  2DO9 A;  3EZQ A;  2GF5 A;  2A5Y B;  4LWD A;  2MS8 A;  4IZ5 E;  1WXP A;  4F44 A;  2HM2 Q;  2G7R A;  1YGO A;  2LWE A;  4P4H A;  3QF2 A;  2YGS A;  2N1F A;  4F42 A;  2F1S A;  1CWW A;  4O9F A;  2DBH A;  2OF5 H;  4O9L A;  2NZ7 A;  4ZBW A;  4A2W A;  2YU0 A;  2L6A A;  2OF5 A;  2LWD A;  4NQK A;  1PN5 A;  4JUP A;  3T6P A;  2N80 A;  2MJM A;  4O7Q A;  4N1L A;  4RHW A;  1D2Z A;  4FH0 A;  3YGS C;  2YQF A;  1N3K A;  4I16 A;  1A1W A;  2BBZ A;  2N7Z A;  4IZA B;  2KN6 A;  1WMG A;  4M9S A;  2L9M A;  1ICH A;  2MB9 A;  3J6J A;  4O6X A;  4RHW E; 
#chains in the Genus database with same CATH homology
 4QOB A;  1E41 A;  1FAD A;  2LS7 A;  2KM6 A;  3YGS P;  1WH4 A;  2NSN A;  2DBF A;  3MOP K;  1E3Y A;  2BBR A;  2MS7 A;  2YVI A;  1UCP A;  3KAT A;  2XV9 A;  2D96 A;  2NAQ A;  4IZ7 B;  4DWN A;  3CRD A;  4D8O A;  3J63 A;  4N1K A;  1A1Z A;  3EZQ B;  4E9M A;  2MN4 A;  4N1J A;  1CY5 A;  1NGR A;  2P1H A;  1DGN A;  2N00 A;  2A9I A;  1D2Z B;  1DDF A;  4UZ0 A;  3MOP G;  4M9Z A;  4EWI A;  2O71 A;  2N97 A;  2DBD A;  1Z6T A;  2B1W A;  2DBG A;  4P4H I;  4M9X A;  3LQR A;  2IB1 A;  4JQW A;  1C15 A;  3MOP A;  2N83 A;  2VGQ A;  4A2Q A;  3LQQ A;  3CL3 A;  2M5V A;  2MPC A;  2DO9 A;  3EZQ A;  2GF5 A;  2A5Y B;  4LWD A;  2MS8 A;  4IZ5 E;  1WXP A;  4F44 A;  2HM2 Q;  2G7R A;  1YGO A;  2LWE A;  4P4H A;  3QF2 A;  2YGS A;  2N1F A;  4F42 A;  2F1S A;  1CWW A;  4O9F A;  2DBH A;  2OF5 H;  4O9L A;  2NZ7 A;  4ZBW A;  4A2W A;  2YU0 A;  2L6A A;  2OF5 A;  2LWD A;  4NQK A;  1PN5 A;  4JUP A;  3T6P A;  2N80 A;  2MJM A;  4O7Q A;  4N1L A;  4RHW A;  1D2Z A;  4FH0 A;  3YGS C;  2YQF A;  1N3K A;  4I16 A;  1A1W A;  2BBZ A;  2N7Z A;  4IZA B;  2KN6 A;  1WMG A;  4M9S A;  2L9M A;  1ICH A;  2MB9 A;  3J6J A;  4O6X A;  4RHW E; 
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