2LSRA

Solution structure of harmonin n terminal domain in complex with a exon68 encoded peptide of cadherin23
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
80
structure length
80
Chain Sequence
MDRKVAREFRHKVDFLIENDAEKDYLYDVLRMYHQTMDVAVLVGDLKLVINEPSRLPLFDAIRPLIPLKHQVEYDQLTPR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Structural protein/cell adhesion
molecule keywords Harmonin
publication title Large protein assemblies formed by multivalent interactions between cadherin23 and harmonin suggest a stable anchorage structure at the tip link of stereocilia
doi rcsb
source organism Homo sapiens
total genus 22
structure length 80
sequence length 80
ec nomenclature
pdb deposition date 2012-05-04
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1160.20 Mainly Alpha Up-down Bundle Paired amphipathic helix 2 (pah2 repeat) Paired amphipathic helix 2 (pah2 repeat) 2lsrA00
4YKDA 4Y5OA 4FQNA 5F3XA 2LSRA 4YL6A 2KBQA 4YKCA 3K1RA 2KBRA
chains in the Genus database with same CATH superfamily
2LD7B 2LSRA 2KBQA 2RMRA 3K1RA 2KBRA 1G1EB 2RMSA 4FQNA 1S5QB 4YKCA 1E91A 4YKDA 4Y5OA 2CR7A 2L9SB 1S5RB 2F05A 5F3XA 4YL6A 2CZYA 1PD7A
chains in the Genus database with same CATH topology
4YKDA 4Y5OA 4FQNA 5F3XA 2LSRA 4YL6A 2KBQA 4YKCA 3K1RA 2KBRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YKD A;  4Y5O A;  4FQN A;  5F3X A;  2LSR A;  4YL6 A;  2KBQ A;  4YKC A;  3K1R A;  2KBR A; 
#chains in the Genus database with same CATH topology
 2LD7 B;  2LSR A;  2KBQ A;  2RMR A;  3K1R A;  2KBR A;  1G1E B;  2RMS A;  4FQN A;  1S5Q B;  4YKC A;  1E91 A;  4YKD A;  4Y5O A;  2CR7 A;  2L9S B;  1S5R B;  2F05 A;  5F3X A;  4YL6 A;  2CZY A;  1PD7 A; 
#chains in the Genus database with same CATH homology
 4YKD A;  4Y5O A;  4FQN A;  5F3X A;  2LSR A;  4YL6 A;  2KBQ A;  4YKC A;  3K1R A;  2KBR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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