2MLRA

Membrane bilayer complex with matrix metalloproteinase-12 at its alpha-face
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
164
structure length
164
Chain Sequence
FREMPGGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDFHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHAIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Ambidextrous binding of cell and membrane bilayers by soluble matrix metalloproteinase-12.
pubmed doi rcsb
molecule keywords Macrophage metalloelastase
molecule tags Hydrolase
source organism Homo sapiens
total genus 42
structure length 164
sequence length 164
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2014-03-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 2mlrA00
1GXDA 2USNA 4PKRA 4H2EA 2CKIA 1XFXA 4H1QA 4HMAA 1G05A 3KMEA 3DWBA 4AUOA 1CIZA 3K7LA 1KUIA 5BOYA 1G4KA 1HTDA 4G9LA 2J83A 1KUFA 1AKLA 1QUAA 1QJJA 1FBLA 1DTHA 1HY7A 3Q2HA 1KAPP 3VTGA 1WNIA 1UMTA 4AYKA 3VI1A 2Y6DA 1IABA 5BOTA 1BKCI 3BA0A 2AYKA 3DPFA 3TS4A 3HBUP 3N2UA 1QIBA 2OI0A 1I1IP 3G5CA 4DF9A 1XFYA 1JIWP 1PWVA 3DL1A 4GWMA 4XCTA 1Y93A 2MLSA 2WO8A 4PKTA 1K7IA 1IAEA 1BZSA 3DNGA 1JANA 2FV9A 2SRTA 3EDHA 1C3IA 3ZUKA 3SHIA 1ASTA 3G42A 4Q1LA 1MMPA 4FVLA 1BQQM 4GQLA 1ND1A 4FXYP 2MLRA 1IAAA 1ZXCA 456CA 4HX3A 4GR0A 1CGFA 1KUHA 3ZXHA 5L7FA 3Q2GA 1JAQA 1R1IA 3NX7A 1BKCA 1HFSA 1KBCA 2MZIA 2DDYA 1YQYA 2OW0A 2QPJA 4H49A 3KHIA 1GKDA 2K9CA 4XBHA 1XUCA 1GE7A 3UVCA 4WKEA 5CUHA 3DSLA 2OXWA 5B5PA 3LILA 2X3BA 4JPAA 2XS4A 1S4BP 3LJTA 4PKQA 2W12A 4AIGA 3HBVP 2OVXA 3LE9A 1A86A 3OHOA 1L6JA 3F1AA 5D2BA 3WV2A 3AYUA 1MMBA 4IJOA 1OMJA 2OY4A 1B8YA 4EFSA 1H71P 2OXUA 1OM7A 2EROA 3O2XA 4PKSA 1CGEA 1GKCA 1JIZA 4ZR5A 1OS2A 1RMZA 2WOAA 3RTTA 3U1RA 3N2VA 3LMCA 2N8RA 1OM8A 3KRYA 1FLSA 4H82A 1HOVA 2OW1A 2OVZA 1D8MA 1BIWA 2OW2A 2OY2A 1AYKA 1D5JA 4JIJA 1XUDA 3ELMA 2JT6A 1MMRA 5B5OA 1JAPA 4DPEA 1HFCA 2HU6A 1MMQA 1GO8P 4GR8A 2OZRA 3KMCA 5I43A 1CAQA 2Y6CA 3F15A 4JP4A 3LKAA 1A85A 3E8RA 3EDZA 4XM6A 3HDBA 3I7GA 1CK7A 1IADA 3LJZA 3LJGA 3LIRA 1CGLA 2J0TA 2CLTA 3P24A 3EHXA 1BUDA 3AIGA 4GUYA 3F18A 1OO9A 4FU4A 3DPEA 1IACA 1CXVA 3LQ0A 4PKVA 1K7QA 3KEJA 5D1TA 4GWNA 1ZTQA 2AIGP 1XFZA 1XURA 2OW9A 3MA2A 5I3MA 2I47A 1C7KA 3B2ZA 1SLMA 1XFUA 3K7NA 1K7GA 1ROSA 1R1JA 1SMPA 1FM1A 4L19A 1PWQA 1UMSA 1GE5A 3HYGA 1SLNA 3TT4A 3LGPA 4L6TA 3F16A 1YP1A 4WZVA 1D7XA 2DW0A 2X7MA 3EDIA 1IAGA 1JH1A 3RTSA 2V4BA 3KECA 1EUBA 1PWPA 4CTHA 3B92A 4H84A 4IUWA 5CZMA 3CKIA 2DW1A 2MZEA 4PKWA 1PWUA 1ZP5A 1G9KA 1OS9A 2JSDA 5JMYA 3HDAP 4H3XA 4GF1A 4R3VA 1QICA 4QKZA 4XM7A 1I76A 4A7BA 3EWJA 4ON1A 2E3XA 1BKCE 1JJ9A 1Y0VA 2DDFA 1GE6A 2Z2DA 3I7IA 2FV5A 3O64A 5I4OA 5L79A 1C8TA 2ERPA 2MZHA 3TSKA 5D1SA 1XFVA 5I2ZA 2X3AA 1R54A 4FXQA 1MNCA 3HB2P 2K2GA 3V96B 966CA 5D7WA 3EHYA 2XS3A 1ATLA 4WF6A 1ZXVA 2RJQA 1PWWA 2YB9A 1EAKA 2W15A 1JK3A 2X3CA 1CQRA 4DD8A 2JT5A 5I12A 2E2DA 4L63A 3F17A 3LQBA 1B3DA 1O0QA 3B8ZA 1HV5A 3HY9A 1YOUA 2W0DA 4G0DA 1JKYA 4PKUA 4WK7A 3KEKA 3EDGA 1SU3A 4XM8A 2OXZA 1USNA 1UTTA 1SATA 1OM6A 1QIAA 4J4MA 4IN9A 2W14A 1BUVM 4I35A 1DMTA 1R55A 3LEAA 2POJA 2D1OA 1Z3JA 5H8XA 2YIGA 1SRPA 4ILWD 3WV1A 3LUMA 4I03A 2DW2A 1RM8A 1EB6A 2O3EA 5BPAA 830CA 1O0TA 1KUKA 2L0RA 1J7NA 5D1UA 2RJPA 4JA1A 1ZS0A 4A3WA 3L0VA 1D8FA 3ZVSA 3LK8A 4H30A 1G49A 1BQOA 1G12A 3WV3A 2PJTA 2ERQA 2JIHA 2D1NA 5LABA 1ZVXA 4JQGA 4GR3A 3F19A 4WKIA 1GO7P 2W13A 2KRJA 3AYKA 1I73A 3LUNA 1QJIA 3TVCA 2WO9A 2A8HA 2TCLA 3HY7A 3OHLA 3GBOA 1BM6A 1YCMA 4H76A 4AXQA 1UEAA 3USNA 4DV8A 1AF0A 5CXAA 1R1HA 1UTZA 1JAOA 2O36A 1Y8JA 3P1VA 3L0TA 3LIKA 2JNPA 1BSWA 1XFWA 1KUGA 5I0LA 3KWVC 5D3CA 1Q3AA
chains in the Genus database with same CATH superfamily
1GXDA 2USNA 4PKRA 4H2EA 2CKIA 1XFXA 4H1QA 4HMAA 1G05A 3KMEA 3DWBA 4AUOA 1CIZA 3K7LA 1KUIA 5BOYA 1G4KA 1HTDA 4G9LA 2J83A 1KUFA 1AKLA 1QUAA 1QJJA 1FBLA 1DTHA 1HY7A 3Q2HA 1KAPP 3VTGA 1WNIA 1UMTA 4AYKA 3VI1A 2Y6DA 1IABA 1OZ9A 5BOTA 1BKCI 3BA0A 2AYKA 3DPFA 3TS4A 3HBUP 3N2UA 1QIBA 2OI0A 1I1IP 3G5CA 4DF9A 1XFYA 1JIWP 1PWVA 3DL1A 4GWMA 4XCTA 1Y93A 2MLSA 2WO8A 4PKTA 1K7IA 1IAEA 1BZSA 3DNGA 1JANA 2FV9A 2SRTA 3EDHA 1C3IA 3ZUKA 3SHIA 1ASTA 3G42A 4Q1LA 1MMPA 4FVLA 1BQQM 4GQLA 1ND1A 4FXYP 2MLRA 1IAAA 1ZXCA 456CA 4HX3A 4GR0A 1CGFA 1KUHA 3ZXHA 5L7FA 3Q2GA 1JAQA 1R1IA 3NX7A 1BKCA 1HFSA 1KBCA 2MZIA 2DDYA 1YQYA 2OW0A 2QPJA 4H49A 3KHIA 1GKDA 2K9CA 4XBHA 1XUCA 1GE7A 3UVCA 4WKEA 5CUHA 3DSLA 2OXWA 5B5PA 3LILA 2X3BA 4JPAA 2XS4A 1S4BP 3LJTA 4PKQA 2W12A 4AIGA 3HBVP 2OVXA 3LE9A 1A86A 3OHOA 1L6JA 3F1AA 5D2BA 3WV2A 3AYUA 1MMBA 4IJOA 1OMJA 2OY4A 1B8YA 4EFSA 1H71P 2OXUA 1OM7A 2EROA 4L7AA 3O2XA 4PKSA 1CGEA 1GKCA 1JIZA 4ZR5A 1OS2A 1RMZA 2WOAA 3RTTA 3U1RA 3N2VA 3LMCA 2N8RA 1OM8A 3KRYA 1FLSA 4H82A 1HOVA 2OW1A 2OVZA 1D8MA 1BIWA 2OW2A 2OY2A 1AYKA 1D5JA 4JIJA 1XUDA 3ELMA 2JT6A 1MMRA 5B5OA 1JAPA 4DPEA 1HFCA 2HU6A 1MMQA 1GO8P 4GR8A 2OZRA 3KMCA 5I43A 1CAQA 2Y6CA 3F15A 4JP4A 3LKAA 1A85A 3E8RA 3EDZA 4XM6A 3HDBA 3I7GA 1CK7A 1IADA 3LJZA 3LJGA 3LIRA 1CGLA 2J0TA 2CLTA 3P24A 3EHXA 1BUDA 3AIGA 4GUYA 3F18A 1OO9A 4FU4A 3DPEA 1IACA 1CXVA 3LQ0A 4PKVA 1K7QA 3KEJA 5D1TA 4GWNA 1ZTQA 2AIGP 1XFZA 1XURA 2OW9A 3MA2A 5I3MA 2I47A 1C7KA 3B2ZA 1SLMA 1XFUA 3K7NA 1K7GA 1ROSA 1R1JA 1SMPA 1FM1A 4L19A 1PWQA 1UMSA 1GE5A 3HYGA 1SLNA 3TT4A 3LGPA 3DTKA 4L6TA 3F16A 1YP1A 4WZVA 1D7XA 2DW0A 2X7MA 3EDIA 1IAGA 1JH1A 3RTSA 2V4BA 3KECA 1EUBA 1PWPA 4CTHA 3B92A 4H84A 4IUWA 5CZMA 3CKIA 2DW1A 2MZEA 4PKWA 1PWUA 1XM5A 1ZP5A 1G9KA 1OS9A 2JSDA 5JMYA 3HDAP 4H3XA 4GF1A 4R3VA 1QICA 4QKZA 4XM7A 1I76A 4A7BA 3EWJA 3DTEA 4ON1A 2E3XA 1BKCE 1JJ9A 1Y0VA 2DDFA 1GE6A 2Z2DA 3I7IA 2FV5A 3O64A 5I4OA 5L79A 1C8TA 2ERPA 2MZHA 3TSKA 5D1SA 1XFVA 5I2ZA 2X3AA 1R54A 4FXQA 1MNCA 3HB2P 2K2GA 3V96B 966CA 5D7WA 3EHYA 2XS3A 1ATLA 4WF6A 1ZXVA 2RJQA 1PWWA 2YB9A 1EAKA 2W15A 1JK3A 2X3CA 1CQRA 4DD8A 2JT5A 5I12A 2E2DA 4L63A 3F17A 3LQBA 1B3DA 1O0QA 3B8ZA 1HV5A 3HY9A 1YOUA 2W0DA 4G0DA 1JKYA 4PKUA 4WK7A 3KEKA 3EDGA 1SU3A 4XM8A 2OXZA 1USNA 1UTTA 1SATA 1OM6A 1QIAA 4J4MA 4IN9A 1XAXA 2W14A 1BUVM 4I35A 1DMTA 1R55A 3LEAA 2POJA 2D1OA 1Z3JA 5H8XA 2YIGA 1SRPA 4ILWD 3WV1A 3LUMA 4I03A 2DW2A 1RM8A 1EB6A 2O3EA 5BPAA 830CA 1O0TA 1KUKA 2L0RA 1J7NA 5D1UA 2RJPA 4JA1A 1ZS0A 4A3WA 3L0VA 1D8FA 3ZVSA 3LK8A 4H30A 1G49A 1BQOA 1G12A 3WV3A 2PJTA 2ERQA 2JIHA 2D1NA 5LABA 1ZVXA 4JQGA 4GR3A 3F19A 3DTIA 4WKIA 1GO7P 2W13A 2KRJA 3AYKA 2YUFA 1I73A 3LUNA 1QJIA 3TVCA 2WO9A 2A8HA 2TCLA 3HY7A 3OHLA 3GBOA 1BM6A 1YCMA 4H76A 4AXQA 1UEAA 3USNA 4DV8A 1AF0A 5CXAA 1R1HA 1UTZA 1JAOA 2O36A 1Y8JA 3P1VA 3L0TA 1TVIA 3LIKA 2JNPA 1BSWA 1XFWA 1KUGA 5I0LA 3KWVC 5D3CA 1Q3AA
chains in the Genus database with same CATH topology
1GXDA 2USNA 4PKRA 4H2EA 2CKIA 1XFXA 4H1QA 4HMAA 1G05A 3KMEA 3DWBA 4AUOA 1CIZA 3K7LA 1KUIA 5BOYA 1G4KA 1HTDA 4G9LA 2J83A 1KUFA 1AKLA 1QUAA 1QJJA 1FBLA 1DTHA 1HY7A 3Q2HA 1KAPP 3VTGA 1WNIA 1UMTA 4AYKA 3VI1A 2Y6DA 1IABA 5BOTA 1BKCI 3BA0A 2AYKA 3DPFA 3TS4A 3HBUP 3N2UA 1QIBA 2OI0A 1I1IP 3G5CA 4DF9A 1XFYA 1JIWP 1PWVA 3DL1A 4GWMA 4XCTA 1Y93A 2MLSA 2WO8A 4PKTA 1K7IA 1IAEA 1BZSA 3DNGA 1JANA 2FV9A 2SRTA 3EDHA 1C3IA 3ZUKA 3SHIA 1ASTA 3G42A 4Q1LA 1MMPA 4FVLA 1BQQM 4GQLA 1ND1A 4FXYP 2MLRA 1IAAA 1ZXCA 456CA 4HX3A 4GR0A 1CGFA 1KUHA 3ZXHA 5L7FA 3Q2GA 1JAQA 1R1IA 3NX7A 1BKCA 1HFSA 1KBCA 2MZIA 2DDYA 1YQYA 2OW0A 2QPJA 4H49A 3KHIA 1GKDA 2K9CA 4XBHA 1XUCA 1GE7A 3UVCA 4WKEA 5CUHA 3DSLA 2OXWA 5B5PA 3LILA 2X3BA 4JPAA 2XS4A 1S4BP 3LJTA 4PKQA 2W12A 4AIGA 3HBVP 2OVXA 3LE9A 1A86A 3OHOA 1L6JA 3F1AA 5D2BA 3WV2A 3AYUA 1MMBA 4IJOA 1OMJA 2OY4A 1B8YA 4EFSA 1H71P 2OXUA 1OM7A 2EROA 4L7AA 3O2XA 4PKSA 1CGEA 1GKCA 1JIZA 4ZR5A 1OS2A 1RMZA 2WOAA 3RTTA 3U1RA 3N2VA 3LMCA 2N8RA 1OM8A 3KRYA 1FLSA 4H82A 1HOVA 2OW1A 2OVZA 1D8MA 1BIWA 2OW2A 2OY2A 1AYKA 1D5JA 4JIJA 1XUDA 3ELMA 2JT6A 1MMRA 5B5OA 1JAPA 4DPEA 1HFCA 2HU6A 1MMQA 1GO8P 4GR8A 2OZRA 3KMCA 5I43A 1CAQA 2Y6CA 3F15A 4JP4A 3LKAA 1A85A 3E8RA 3EDZA 4XM6A 3HDBA 3I7GA 1CK7A 1IADA 3LJZA 3LJGA 3LIRA 1CGLA 2J0TA 2CLTA 3P24A 3EHXA 1BUDA 3AIGA 4GUYA 3F18A 1OO9A 4FU4A 3DPEA 1IACA 1CXVA 3LQ0A 4PKVA 1K7QA 3KEJA 5D1TA 4GWNA 1ZTQA 2AIGP 1XFZA 1XURA 2OW9A 3MA2A 5I3MA 2I47A 1C7KA 3B2ZA 1SLMA 1XFUA 3K7NA 1K7GA 1ROSA 1R1JA 1SMPA 1FM1A 4L19A 1PWQA 1UMSA 1GE5A 3HYGA 1SLNA 3TT4A 3LGPA 3DTKA 4L6TA 3F16A 1YP1A 4WZVA 1D7XA 2DW0A 2X7MA 3EDIA 1IAGA 1JH1A 3RTSA 2V4BA 3KECA 1EUBA 1PWPA 4CTHA 3B92A 4H84A 4IUWA 5CZMA 3CKIA 2DW1A 2MZEA 4PKWA 1PWUA 1ZP5A 1G9KA 1OS9A 2JSDA 5JMYA 3HDAP 4H3XA 4GF1A 4R3VA 1QICA 4QKZA 4XM7A 1I76A 4A7BA 3EWJA 3DTEA 4ON1A 2E3XA 1BKCE 1JJ9A 1Y0VA 2DDFA 1GE6A 2Z2DA 3I7IA 2FV5A 3O64A 5I4OA 5L79A 1C8TA 2ERPA 2MZHA 3TSKA 5D1SA 1XFVA 5I2ZA 2X3AA 1R54A 4FXQA 1MNCA 3HB2P 2K2GA 3V96B 966CA 5D7WA 3EHYA 2XS3A 1ATLA 4WF6A 1ZXVA 2RJQA 1PWWA 2YB9A 1EAKA 2W15A 1JK3A 2X3CA 1CQRA 4DD8A 2JT5A 5I12A 2E2DA 4L63A 3F17A 3LQBA 1B3DA 1O0QA 3B8ZA 1HV5A 3HY9A 1YOUA 2W0DA 4G0DA 1JKYA 4PKUA 4WK7A 3KEKA 3EDGA 1SU3A 4XM8A 2OXZA 1USNA 1UTTA 1SATA 1OM6A 1QIAA 4J4MA 4IN9A 2W14A 1BUVM 4I35A 1DMTA 1R55A 3LEAA 2POJA 2D1OA 1Z3JA 5H8XA 2YIGA 1SRPA 4ILWD 3WV1A 3LUMA 4I03A 2DW2A 1RM8A 1EB6A 2O3EA 5BPAA 830CA 1O0TA 1KUKA 2L0RA 1J7NA 5D1UA 2RJPA 4JA1A 1ZS0A 4A3WA 3L0VA 1D8FA 3ZVSA 3LK8A 4H30A 1G49A 1BQOA 1G12A 3WV3A 2PJTA 2ERQA 2JIHA 2D1NA 5LABA 1ZVXA 4JQGA 4GR3A 3F19A 3DTIA 4WKIA 1GO7P 2W13A 2KRJA 3AYKA 2YUFA 1I73A 3LUNA 1QJIA 3TVCA 2WO9A 2A8HA 2TCLA 3HY7A 3OHLA 3GBOA 1BM6A 1YCMA 4H76A 4AXQA 1UEAA 3USNA 4DV8A 1AF0A 5CXAA 1R1HA 1UTZA 1JAOA 2O36A 1Y8JA 3P1VA 3L0TA 3LIKA 2JNPA 1BSWA 1XFWA 1KUGA 5I0LA 3KWVC 5D3CA 1Q3AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GXD A;  2USN A;  4PKR A;  4H2E A;  2CKI A;  1XFX A;  4H1Q A;  4HMA A;  1G05 A;  3KME A;  3DWB A;  4AUO A;  1CIZ A;  3K7L A;  1KUI A;  5BOY A;  1G4K A;  1HTD A;  4G9L A;  2J83 A;  1KUF A;  1AKL A;  1QUA A;  1QJJ A;  1FBL A;  1DTH A;  1HY7 A;  3Q2H A;  1KAP P;  3VTG A;  1WNI A;  1UMT A;  4AYK A;  3VI1 A;  2Y6D A;  1IAB A;  5BOT A;  1BKC I;  3BA0 A;  2AYK A;  3DPF A;  3TS4 A;  3HBU P;  3N2U A;  1QIB A;  2OI0 A;  1I1I P;  3G5C A;  4DF9 A;  1XFY A;  1JIW P;  1PWV A;  3DL1 A;  4GWM A;  4XCT A;  1Y93 A;  2MLS A;  2WO8 A;  4PKT A;  1K7I A;  1IAE A;  1BZS A;  3DNG A;  1JAN A;  2FV9 A;  2SRT A;  3EDH A;  1C3I A;  3ZUK A;  3SHI A;  1AST A;  3G42 A;  4Q1L A;  1MMP A;  4FVL A;  1BQQ M;  4GQL A;  1ND1 A;  4FXY P;  2MLR A;  1IAA A;  1ZXC A;  456C A;  4HX3 A;  4GR0 A;  1CGF A;  1KUH A;  3ZXH A;  5L7F A;  3Q2G A;  1JAQ A;  1R1I A;  3NX7 A;  1BKC A;  1HFS A;  1KBC A;  2MZI A;  2DDY A;  1YQY A;  2OW0 A;  2QPJ A;  4H49 A;  3KHI A;  1GKD A;  2K9C A;  4XBH A;  1XUC A;  1GE7 A;  3UVC A;  4WKE A;  5CUH A;  3DSL A;  2OXW A;  5B5P A;  3LIL A;  2X3B A;  4JPA A;  2XS4 A;  1S4B P;  3LJT A;  4PKQ A;  2W12 A;  4AIG A;  3HBV P;  2OVX A;  3LE9 A;  1A86 A;  3OHO A;  1L6J A;  3F1A A;  5D2B A;  3WV2 A;  3AYU A;  1MMB A;  4IJO A;  1OMJ A;  2OY4 A;  1B8Y A;  4EFS A;  1H71 P;  2OXU A;  1OM7 A;  2ERO A;  3O2X A;  4PKS A;  1CGE A;  1GKC A;  1JIZ A;  4ZR5 A;  1OS2 A;  1RMZ A;  2WOA A;  3RTT A;  3U1R A;  3N2V A;  3LMC A;  2N8R A;  1OM8 A;  3KRY A;  1FLS A;  4H82 A;  1HOV A;  2OW1 A;  2OVZ A;  1D8M A;  1BIW A;  2OW2 A;  2OY2 A;  1AYK A;  1D5J A;  4JIJ A;  1XUD A;  3ELM A;  2JT6 A;  1MMR A;  5B5O A;  1JAP A;  4DPE A;  1HFC A;  2HU6 A;  1MMQ A;  1GO8 P;  4GR8 A;  2OZR A;  3KMC A;  5I43 A;  1CAQ A;  2Y6C A;  3F15 A;  4JP4 A;  3LKA A;  1A85 A;  3E8R A;  3EDZ A;  4XM6 A;  3HDB A;  3I7G A;  1CK7 A;  1IAD A;  3LJZ A;  3LJG A;  3LIR A;  1CGL A;  2J0T A;  2CLT A;  3P24 A;  3EHX A;  1BUD A;  3AIG A;  4GUY A;  3F18 A;  1OO9 A;  4FU4 A;  3DPE A;  1IAC A;  1CXV A;  3LQ0 A;  4PKV A;  1K7Q A;  3KEJ A;  5D1T A;  4GWN A;  1ZTQ A;  2AIG P;  1XFZ A;  1XUR A;  2OW9 A;  3MA2 A;  5I3M A;  2I47 A;  1C7K A;  3B2Z A;  1SLM A;  1XFU A;  3K7N A;  1K7G A;  1ROS A;  1R1J A;  1SMP A;  1FM1 A;  4L19 A;  1PWQ A;  1UMS A;  1GE5 A;  3HYG A;  1SLN A;  3TT4 A;  3LGP A;  4L6T A;  3F16 A;  1YP1 A;  4WZV A;  1D7X A;  2DW0 A;  2X7M A;  3EDI A;  1IAG A;  1JH1 A;  3RTS A;  2V4B A;  3KEC A;  1EUB A;  1PWP A;  4CTH A;  3B92 A;  4H84 A;  4IUW A;  5CZM A;  3CKI A;  2DW1 A;  2MZE A;  4PKW A;  1PWU A;  1ZP5 A;  1G9K A;  1OS9 A;  2JSD A;  5JMY A;  3HDA P;  4H3X A;  4GF1 A;  4R3V A;  1QIC A;  4QKZ A;  4XM7 A;  1I76 A;  4A7B A;  3EWJ A;  4ON1 A;  2E3X A;  1BKC E;  1JJ9 A;  1Y0V A;  2DDF A;  1GE6 A;  2Z2D A;  3I7I A;  2FV5 A;  3O64 A;  5I4O A;  5L79 A;  1C8T A;  2ERP A;  2MZH A;  3TSK A;  5D1S A;  1XFV A;  5I2Z A;  2X3A A;  1R54 A;  4FXQ A;  1MNC A;  3HB2 P;  2K2G A;  3V96 B;  966C A;  5D7W A;  3EHY A;  2XS3 A;  1ATL A;  4WF6 A;  1ZXV A;  2RJQ A;  1PWW A;  2YB9 A;  1EAK A;  2W15 A;  1JK3 A;  2X3C A;  1CQR A;  4DD8 A;  2JT5 A;  5I12 A;  2E2D A;  4L63 A;  3F17 A;  3LQB A;  1B3D A;  1O0Q A;  3B8Z A;  1HV5 A;  3HY9 A;  1YOU A;  2W0D A;  4G0D A;  1JKY A;  4PKU A;  4WK7 A;  3KEK A;  3EDG A;  1SU3 A;  4XM8 A;  2OXZ A;  1USN A;  1UTT A;  1SAT A;  1OM6 A;  1QIA A;  4J4M A;  4IN9 A;  2W14 A;  1BUV M;  4I35 A;  1DMT A;  1R55 A;  3LEA A;  2POJ A;  2D1O A;  1Z3J A;  5H8X A;  2YIG A;  1SRP A;  4ILW D;  3WV1 A;  3LUM A;  4I03 A;  2DW2 A;  1RM8 A;  1EB6 A;  2O3E A;  5BPA A;  830C A;  1O0T A;  1KUK A;  2L0R A;  1J7N A;  5D1U A;  2RJP A;  4JA1 A;  1ZS0 A;  4A3W A;  3L0V A;  1D8F A;  3ZVS A;  3LK8 A;  4H30 A;  1G49 A;  1BQO A;  1G12 A;  3WV3 A;  2PJT A;  2ERQ A;  2JIH A;  2D1N A;  5LAB A;  1ZVX A;  4JQG A;  4GR3 A;  3F19 A;  4WKI A;  1GO7 P;  2W13 A;  2KRJ A;  3AYK A;  1I73 A;  3LUN A;  1QJI A;  3TVC A;  2WO9 A;  2A8H A;  2TCL A;  3HY7 A;  3OHL A;  3GBO A;  1BM6 A;  1YCM A;  4H76 A;  4AXQ A;  1UEA A;  3USN A;  4DV8 A;  1AF0 A;  5CXA A;  1R1H A;  1UTZ A;  1JAO A;  2O36 A;  1Y8J A;  3P1V A;  3L0T A;  3LIK A;  2JNP A;  1BSW A;  1XFW A;  1KUG A;  5I0L A;  3KWV C;  5D3C A;  1Q3A A; 
#chains in the Genus database with same CATH topology
 1GXD A;  2USN A;  4PKR A;  4H2E A;  2CKI A;  1XFX A;  4H1Q A;  4HMA A;  1G05 A;  3KME A;  3DWB A;  4AUO A;  1CIZ A;  3K7L A;  1KUI A;  5BOY A;  1G4K A;  1HTD A;  4G9L A;  2J83 A;  1KUF A;  1AKL A;  1QUA A;  1QJJ A;  1FBL A;  1DTH A;  1HY7 A;  3Q2H A;  1KAP P;  3VTG A;  1WNI A;  1UMT A;  4AYK A;  3VI1 A;  2Y6D A;  1IAB A;  1OZ9 A;  5BOT A;  1BKC I;  3BA0 A;  2AYK A;  3DPF A;  3TS4 A;  3HBU P;  3N2U A;  1QIB A;  2OI0 A;  1I1I P;  3G5C A;  4DF9 A;  1XFY A;  1JIW P;  1PWV A;  3DL1 A;  4GWM A;  4XCT A;  1Y93 A;  2MLS A;  2WO8 A;  4PKT A;  1K7I A;  1IAE A;  1BZS A;  3DNG A;  1JAN A;  2FV9 A;  2SRT A;  3EDH A;  1C3I A;  3ZUK A;  3SHI A;  1AST A;  3G42 A;  4Q1L A;  1MMP A;  4FVL A;  1BQQ M;  4GQL A;  1ND1 A;  4FXY P;  2MLR A;  1IAA A;  1ZXC A;  456C A;  4HX3 A;  4GR0 A;  1CGF A;  1KUH A;  3ZXH A;  5L7F A;  3Q2G A;  1JAQ A;  1R1I A;  3NX7 A;  1BKC A;  1HFS A;  1KBC A;  2MZI A;  2DDY A;  1YQY A;  2OW0 A;  2QPJ A;  4H49 A;  3KHI A;  1GKD A;  2K9C A;  4XBH A;  1XUC A;  1GE7 A;  3UVC A;  4WKE A;  5CUH A;  3DSL A;  2OXW A;  5B5P A;  3LIL A;  2X3B A;  4JPA A;  2XS4 A;  1S4B P;  3LJT A;  4PKQ A;  2W12 A;  4AIG A;  3HBV P;  2OVX A;  3LE9 A;  1A86 A;  3OHO A;  1L6J A;  3F1A A;  5D2B A;  3WV2 A;  3AYU A;  1MMB A;  4IJO A;  1OMJ A;  2OY4 A;  1B8Y A;  4EFS A;  1H71 P;  2OXU A;  1OM7 A;  2ERO A;  4L7A A;  3O2X A;  4PKS A;  1CGE A;  1GKC A;  1JIZ A;  4ZR5 A;  1OS2 A;  1RMZ A;  2WOA A;  3RTT A;  3U1R A;  3N2V A;  3LMC A;  2N8R A;  1OM8 A;  3KRY A;  1FLS A;  4H82 A;  1HOV A;  2OW1 A;  2OVZ A;  1D8M A;  1BIW A;  2OW2 A;  2OY2 A;  1AYK A;  1D5J A;  4JIJ A;  1XUD A;  3ELM A;  2JT6 A;  1MMR A;  5B5O A;  1JAP A;  4DPE A;  1HFC A;  2HU6 A;  1MMQ A;  1GO8 P;  4GR8 A;  2OZR A;  3KMC A;  5I43 A;  1CAQ A;  2Y6C A;  3F15 A;  4JP4 A;  3LKA A;  1A85 A;  3E8R A;  3EDZ A;  4XM6 A;  3HDB A;  3I7G A;  1CK7 A;  1IAD A;  3LJZ A;  3LJG A;  3LIR A;  1CGL A;  2J0T A;  2CLT A;  3P24 A;  3EHX A;  1BUD A;  3AIG A;  4GUY A;  3F18 A;  1OO9 A;  4FU4 A;  3DPE A;  1IAC A;  1CXV A;  3LQ0 A;  4PKV A;  1K7Q A;  3KEJ A;  5D1T A;  4GWN A;  1ZTQ A;  2AIG P;  1XFZ A;  1XUR A;  2OW9 A;  3MA2 A;  5I3M A;  2I47 A;  1C7K A;  3B2Z A;  1SLM A;  1XFU A;  3K7N A;  1K7G A;  1ROS A;  1R1J A;  1SMP A;  1FM1 A;  4L19 A;  1PWQ A;  1UMS A;  1GE5 A;  3HYG A;  1SLN A;  3TT4 A;  3LGP A;  3DTK A;  4L6T A;  3F16 A;  1YP1 A;  4WZV A;  1D7X A;  2DW0 A;  2X7M A;  3EDI A;  1IAG A;  1JH1 A;  3RTS A;  2V4B A;  3KEC A;  1EUB A;  1PWP A;  4CTH A;  3B92 A;  4H84 A;  4IUW A;  5CZM A;  3CKI A;  2DW1 A;  2MZE A;  4PKW A;  1PWU A;  1XM5 A;  1ZP5 A;  1G9K A;  1OS9 A;  2JSD A;  5JMY A;  3HDA P;  4H3X A;  4GF1 A;  4R3V A;  1QIC A;  4QKZ A;  4XM7 A;  1I76 A;  4A7B A;  3EWJ A;  3DTE A;  4ON1 A;  2E3X A;  1BKC E;  1JJ9 A;  1Y0V A;  2DDF A;  1GE6 A;  2Z2D A;  3I7I A;  2FV5 A;  3O64 A;  5I4O A;  5L79 A;  1C8T A;  2ERP A;  2MZH A;  3TSK A;  5D1S A;  1XFV A;  5I2Z A;  2X3A A;  1R54 A;  4FXQ A;  1MNC A;  3HB2 P;  2K2G A;  3V96 B;  966C A;  5D7W A;  3EHY A;  2XS3 A;  1ATL A;  4WF6 A;  1ZXV A;  2RJQ A;  1PWW A;  2YB9 A;  1EAK A;  2W15 A;  1JK3 A;  2X3C A;  1CQR A;  4DD8 A;  2JT5 A;  5I12 A;  2E2D A;  4L63 A;  3F17 A;  3LQB A;  1B3D A;  1O0Q A;  3B8Z A;  1HV5 A;  3HY9 A;  1YOU A;  2W0D A;  4G0D A;  1JKY A;  4PKU A;  4WK7 A;  3KEK A;  3EDG A;  1SU3 A;  4XM8 A;  2OXZ A;  1USN A;  1UTT A;  1SAT A;  1OM6 A;  1QIA A;  4J4M A;  4IN9 A;  1XAX A;  2W14 A;  1BUV M;  4I35 A;  1DMT A;  1R55 A;  3LEA A;  2POJ A;  2D1O A;  1Z3J A;  5H8X A;  2YIG A;  1SRP A;  4ILW D;  3WV1 A;  3LUM A;  4I03 A;  2DW2 A;  1RM8 A;  1EB6 A;  2O3E A;  5BPA A;  830C A;  1O0T A;  1KUK A;  2L0R A;  1J7N A;  5D1U A;  2RJP A;  4JA1 A;  1ZS0 A;  4A3W A;  3L0V A;  1D8F A;  3ZVS A;  3LK8 A;  4H30 A;  1G49 A;  1BQO A;  1G12 A;  3WV3 A;  2PJT A;  2ERQ A;  2JIH A;  2D1N A;  5LAB A;  1ZVX A;  4JQG A;  4GR3 A;  3F19 A;  3DTI A;  4WKI A;  1GO7 P;  2W13 A;  2KRJ A;  3AYK A;  2YUF A;  1I73 A;  3LUN A;  1QJI A;  3TVC A;  2WO9 A;  2A8H A;  2TCL A;  3HY7 A;  3OHL A;  3GBO A;  1BM6 A;  1YCM A;  4H76 A;  4AXQ A;  1UEA A;  3USN A;  4DV8 A;  1AF0 A;  5CXA A;  1R1H A;  1UTZ A;  1JAO A;  2O36 A;  1Y8J A;  3P1V A;  3L0T A;  1TVI A;  3LIK A;  2JNP A;  1BSW A;  1XFW A;  1KUG A;  5I0L A;  3KWV C;  5D3C A;  1Q3A A; 
#chains in the Genus database with same CATH homology
 1GXD A;  2USN A;  4PKR A;  4H2E A;  2CKI A;  1XFX A;  4H1Q A;  4HMA A;  1G05 A;  3KME A;  3DWB A;  4AUO A;  1CIZ A;  3K7L A;  1KUI A;  5BOY A;  1G4K A;  1HTD A;  4G9L A;  2J83 A;  1KUF A;  1AKL A;  1QUA A;  1QJJ A;  1FBL A;  1DTH A;  1HY7 A;  3Q2H A;  1KAP P;  3VTG A;  1WNI A;  1UMT A;  4AYK A;  3VI1 A;  2Y6D A;  1IAB A;  5BOT A;  1BKC I;  3BA0 A;  2AYK A;  3DPF A;  3TS4 A;  3HBU P;  3N2U A;  1QIB A;  2OI0 A;  1I1I P;  3G5C A;  4DF9 A;  1XFY A;  1JIW P;  1PWV A;  3DL1 A;  4GWM A;  4XCT A;  1Y93 A;  2MLS A;  2WO8 A;  4PKT A;  1K7I A;  1IAE A;  1BZS A;  3DNG A;  1JAN A;  2FV9 A;  2SRT A;  3EDH A;  1C3I A;  3ZUK A;  3SHI A;  1AST A;  3G42 A;  4Q1L A;  1MMP A;  4FVL A;  1BQQ M;  4GQL A;  1ND1 A;  4FXY P;  2MLR A;  1IAA A;  1ZXC A;  456C A;  4HX3 A;  4GR0 A;  1CGF A;  1KUH A;  3ZXH A;  5L7F A;  3Q2G A;  1JAQ A;  1R1I A;  3NX7 A;  1BKC A;  1HFS A;  1KBC A;  2MZI A;  2DDY A;  1YQY A;  2OW0 A;  2QPJ A;  4H49 A;  3KHI A;  1GKD A;  2K9C A;  4XBH A;  1XUC A;  1GE7 A;  3UVC A;  4WKE A;  5CUH A;  3DSL A;  2OXW A;  5B5P A;  3LIL A;  2X3B A;  4JPA A;  2XS4 A;  1S4B P;  3LJT A;  4PKQ A;  2W12 A;  4AIG A;  3HBV P;  2OVX A;  3LE9 A;  1A86 A;  3OHO A;  1L6J A;  3F1A A;  5D2B A;  3WV2 A;  3AYU A;  1MMB A;  4IJO A;  1OMJ A;  2OY4 A;  1B8Y A;  4EFS A;  1H71 P;  2OXU A;  1OM7 A;  2ERO A;  4L7A A;  3O2X A;  4PKS A;  1CGE A;  1GKC A;  1JIZ A;  4ZR5 A;  1OS2 A;  1RMZ A;  2WOA A;  3RTT A;  3U1R A;  3N2V A;  3LMC A;  2N8R A;  1OM8 A;  3KRY A;  1FLS A;  4H82 A;  1HOV A;  2OW1 A;  2OVZ A;  1D8M A;  1BIW A;  2OW2 A;  2OY2 A;  1AYK A;  1D5J A;  4JIJ A;  1XUD A;  3ELM A;  2JT6 A;  1MMR A;  5B5O A;  1JAP A;  4DPE A;  1HFC A;  2HU6 A;  1MMQ A;  1GO8 P;  4GR8 A;  2OZR A;  3KMC A;  5I43 A;  1CAQ A;  2Y6C A;  3F15 A;  4JP4 A;  3LKA A;  1A85 A;  3E8R A;  3EDZ A;  4XM6 A;  3HDB A;  3I7G A;  1CK7 A;  1IAD A;  3LJZ A;  3LJG A;  3LIR A;  1CGL A;  2J0T A;  2CLT A;  3P24 A;  3EHX A;  1BUD A;  3AIG A;  4GUY A;  3F18 A;  1OO9 A;  4FU4 A;  3DPE A;  1IAC A;  1CXV A;  3LQ0 A;  4PKV A;  1K7Q A;  3KEJ A;  5D1T A;  4GWN A;  1ZTQ A;  2AIG P;  1XFZ A;  1XUR A;  2OW9 A;  3MA2 A;  5I3M A;  2I47 A;  1C7K A;  3B2Z A;  1SLM A;  1XFU A;  3K7N A;  1K7G A;  1ROS A;  1R1J A;  1SMP A;  1FM1 A;  4L19 A;  1PWQ A;  1UMS A;  1GE5 A;  3HYG A;  1SLN A;  3TT4 A;  3LGP A;  3DTK A;  4L6T A;  3F16 A;  1YP1 A;  4WZV A;  1D7X A;  2DW0 A;  2X7M A;  3EDI A;  1IAG A;  1JH1 A;  3RTS A;  2V4B A;  3KEC A;  1EUB A;  1PWP A;  4CTH A;  3B92 A;  4H84 A;  4IUW A;  5CZM A;  3CKI A;  2DW1 A;  2MZE A;  4PKW A;  1PWU A;  1ZP5 A;  1G9K A;  1OS9 A;  2JSD A;  5JMY A;  3HDA P;  4H3X A;  4GF1 A;  4R3V A;  1QIC A;  4QKZ A;  4XM7 A;  1I76 A;  4A7B A;  3EWJ A;  3DTE A;  4ON1 A;  2E3X A;  1BKC E;  1JJ9 A;  1Y0V A;  2DDF A;  1GE6 A;  2Z2D A;  3I7I A;  2FV5 A;  3O64 A;  5I4O A;  5L79 A;  1C8T A;  2ERP A;  2MZH A;  3TSK A;  5D1S A;  1XFV A;  5I2Z A;  2X3A A;  1R54 A;  4FXQ A;  1MNC A;  3HB2 P;  2K2G A;  3V96 B;  966C A;  5D7W A;  3EHY A;  2XS3 A;  1ATL A;  4WF6 A;  1ZXV A;  2RJQ A;  1PWW A;  2YB9 A;  1EAK A;  2W15 A;  1JK3 A;  2X3C A;  1CQR A;  4DD8 A;  2JT5 A;  5I12 A;  2E2D A;  4L63 A;  3F17 A;  3LQB A;  1B3D A;  1O0Q A;  3B8Z A;  1HV5 A;  3HY9 A;  1YOU A;  2W0D A;  4G0D A;  1JKY A;  4PKU A;  4WK7 A;  3KEK A;  3EDG A;  1SU3 A;  4XM8 A;  2OXZ A;  1USN A;  1UTT A;  1SAT A;  1OM6 A;  1QIA A;  4J4M A;  4IN9 A;  2W14 A;  1BUV M;  4I35 A;  1DMT A;  1R55 A;  3LEA A;  2POJ A;  2D1O A;  1Z3J A;  5H8X A;  2YIG A;  1SRP A;  4ILW D;  3WV1 A;  3LUM A;  4I03 A;  2DW2 A;  1RM8 A;  1EB6 A;  2O3E A;  5BPA A;  830C A;  1O0T A;  1KUK A;  2L0R A;  1J7N A;  5D1U A;  2RJP A;  4JA1 A;  1ZS0 A;  4A3W A;  3L0V A;  1D8F A;  3ZVS A;  3LK8 A;  4H30 A;  1G49 A;  1BQO A;  1G12 A;  3WV3 A;  2PJT A;  2ERQ A;  2JIH A;  2D1N A;  5LAB A;  1ZVX A;  4JQG A;  4GR3 A;  3F19 A;  3DTI A;  4WKI A;  1GO7 P;  2W13 A;  2KRJ A;  3AYK A;  2YUF A;  1I73 A;  3LUN A;  1QJI A;  3TVC A;  2WO9 A;  2A8H A;  2TCL A;  3HY7 A;  3OHL A;  3GBO A;  1BM6 A;  1YCM A;  4H76 A;  4AXQ A;  1UEA A;  3USN A;  4DV8 A;  1AF0 A;  5CXA A;  1R1H A;  1UTZ A;  1JAO A;  2O36 A;  1Y8J A;  3P1V A;  3L0T A;  3LIK A;  2JNP A;  1BSW A;  1XFW A;  1KUG A;  5I0L A;  3KWV C;  5D3C A;  1Q3A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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