2MN4A

Nmr solution structure of a computational designed protein based on structure template 1cy5
Total Genus 25
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
94
structure length
94
Chain Sequence
MTPEQREFLPEILAEIIANLDPTKILEELLRRGLLTPAELQEVLDLKTPEEQAKKLIDFILKLSPADVQARINVLRAHGYQALADKLNKYLTLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Protein design with a comprehensive statistical energy function and boosted by experimental selection for foldability
pubmed doi rcsb
molecule tags De novo protein
source organism Synthetic
molecule keywords Computational designed protein based on structure template 1
total genus 25
structure length 94
sequence length 94
ec nomenclature
pdb deposition date 2014-03-28
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 2mn4A00
4F42A 2OF5A 2VGQA 2L9MA 2KM6A 4FH0A 2BBZA 4JQWA 4M9XA 1E3YA 2G7RA 2YGSA 2N00A 2NZ7A 2N1FA 4EWIA 1UCPA 2N7ZA 2MS8A 2IB1A 1DDFA 2L6AA 1A1WA 1Z6TA 3EZQB 1WXPA 2DBHA 2MN4A 2F1SA 3QF2A 2DO9A 2MB9A 1N3KA 3YGSC 4E9MA 1CY5A 2B1WA 2D96A 2O71A 4NQKA 3MOPG 1YGOA 4RHWA 2BBRA 1NGRA 2DBDA 3J6JA 1D2ZA 3YGSP 2LWEA 1ICHA 2LS7A 3CRDA 2A5YB 3CL3A 2MPCA 2A9IA 2YQFA 1C15A 4F44A 4P4HA 2NSNA 2OF5H 4P4HI 4A2WA 4O6XA 3KATA 4UZ0A 4M9ZA 4N1JA 4D8OA 4N1LA 1WMGA 4N1KA 2DBFA 4O9LA 3T6PA 4QOBA 2DBGA 3LQRA 4ZBWA 2MS7A 3EZQA 4IZAB 4I16A 4M9SA 2M5VA 4DWNA 2GF5A 4A2QA 1D2ZB 2N83A 4LWDA 1WH4A 2LWDA 4JUPA 3MOPA 2YU0A 2N97A 4RHWE 1FADA 1PN5A 3J63A 1DGNA 3LQQA 2P1HA 1E41A 2HM2Q 1CWWA 4IZ5E 3MOPK 2YVIA 4O7QA 2KN6A 4O9FA 4IZ7B 2NAQA 2N80A 1A1ZA
chains in the Genus database with same CATH superfamily
4F42A 2OF5A 2VGQA 2L9MA 2KM6A 4FH0A 2BBZA 4JQWA 4M9XA 1E3YA 2G7RA 2YGSA 2N00A 2NZ7A 2N1FA 4EWIA 1UCPA 2N7ZA 2MJMA 2MS8A 2IB1A 1DDFA 2L6AA 1A1WA 1Z6TA 3EZQB 1WXPA 2DBHA 2MN4A 2F1SA 3QF2A 2DO9A 2MB9A 1N3KA 3YGSC 4E9MA 1CY5A 2B1WA 2D96A 2O71A 4NQKA 3MOPG 1YGOA 4RHWA 2BBRA 1NGRA 2DBDA 3J6JA 1D2ZA 3YGSP 2LWEA 1ICHA 2LS7A 3CRDA 2A5YB 3CL3A 2MPCA 2A9IA 2YQFA 1C15A 4F44A 4P4HA 2NSNA 2OF5H 4P4HI 4A2WA 4O6XA 3KATA 4UZ0A 4M9ZA 4N1JA 4D8OA 4N1LA 1WMGA 4N1KA 2DBFA 4O9LA 3T6PA 4QOBA 2DBGA 3LQRA 4ZBWA 2MS7A 3EZQA 4IZAB 4I16A 4M9SA 2M5VA 4DWNA 2GF5A 4A2QA 1D2ZB 2N83A 4LWDA 2XV9A 1WH4A 2LWDA 4JUPA 3MOPA 2YU0A 2N97A 4RHWE 1FADA 1PN5A 3J63A 1DGNA 3LQQA 2P1HA 1E41A 2HM2Q 1CWWA 4IZ5E 3MOPK 2YVIA 4O7QA 2KN6A 4O9FA 4IZ7B 2NAQA 2N80A 1A1ZA
chains in the Genus database with same CATH topology
4F42A 2OF5A 2VGQA 2L9MA 2KM6A 4FH0A 2BBZA 4JQWA 4M9XA 1E3YA 2G7RA 2YGSA 2N00A 2NZ7A 2N1FA 4EWIA 1UCPA 2N7ZA 2MJMA 2MS8A 2IB1A 1DDFA 2L6AA 1A1WA 1Z6TA 3EZQB 1WXPA 2DBHA 2MN4A 2F1SA 3QF2A 2DO9A 2MB9A 1N3KA 3YGSC 4E9MA 1CY5A 2B1WA 2D96A 2O71A 4NQKA 3MOPG 1YGOA 4RHWA 2BBRA 1NGRA 2DBDA 3J6JA 1D2ZA 3YGSP 2LWEA 1ICHA 2LS7A 3CRDA 2A5YB 3CL3A 2MPCA 2A9IA 2YQFA 1C15A 4F44A 4P4HA 2NSNA 2OF5H 4P4HI 4A2WA 4O6XA 3KATA 4UZ0A 4M9ZA 4N1JA 4D8OA 4N1LA 1WMGA 4N1KA 2DBFA 4O9LA 3T6PA 4QOBA 2DBGA 3LQRA 4ZBWA 2MS7A 3EZQA 4IZAB 4I16A 4M9SA 2M5VA 4DWNA 2GF5A 4A2QA 1D2ZB 2N83A 4LWDA 2XV9A 1WH4A 2LWDA 4JUPA 3MOPA 2YU0A 2N97A 4RHWE 1FADA 1PN5A 3J63A 1DGNA 3LQQA 2P1HA 1E41A 2HM2Q 1CWWA 4IZ5E 3MOPK 2YVIA 4O7QA 2KN6A 4O9FA 4IZ7B 2NAQA 2N80A 1A1ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4F42 A;  2OF5 A;  2VGQ A;  2L9M A;  2KM6 A;  4FH0 A;  2BBZ A;  4JQW A;  4M9X A;  1E3Y A;  2G7R A;  2YGS A;  2N00 A;  2NZ7 A;  2N1F A;  4EWI A;  1UCP A;  2N7Z A;  2MS8 A;  2IB1 A;  1DDF A;  2L6A A;  1A1W A;  1Z6T A;  3EZQ B;  1WXP A;  2DBH A;  2MN4 A;  2F1S A;  3QF2 A;  2DO9 A;  2MB9 A;  1N3K A;  3YGS C;  4E9M A;  1CY5 A;  2B1W A;  2D96 A;  2O71 A;  4NQK A;  3MOP G;  1YGO A;  4RHW A;  2BBR A;  1NGR A;  2DBD A;  3J6J A;  1D2Z A;  3YGS P;  2LWE A;  1ICH A;  2LS7 A;  3CRD A;  2A5Y B;  3CL3 A;  2MPC A;  2A9I A;  2YQF A;  1C15 A;  4F44 A;  4P4H A;  2NSN A;  2OF5 H;  4P4H I;  4A2W A;  4O6X A;  3KAT A;  4UZ0 A;  4M9Z A;  4N1J A;  4D8O A;  4N1L A;  1WMG A;  4N1K A;  2DBF A;  4O9L A;  3T6P A;  4QOB A;  2DBG A;  3LQR A;  4ZBW A;  2MS7 A;  3EZQ A;  4IZA B;  4I16 A;  4M9S A;  2M5V A;  4DWN A;  2GF5 A;  4A2Q A;  1D2Z B;  2N83 A;  4LWD A;  1WH4 A;  2LWD A;  4JUP A;  3MOP A;  2YU0 A;  2N97 A;  4RHW E;  1FAD A;  1PN5 A;  3J63 A;  1DGN A;  3LQQ A;  2P1H A;  1E41 A;  2HM2 Q;  1CWW A;  4IZ5 E;  3MOP K;  2YVI A;  4O7Q A;  2KN6 A;  4O9F A;  4IZ7 B;  2NAQ A;  2N80 A;  1A1Z A; 
#chains in the Genus database with same CATH topology
 4F42 A;  2OF5 A;  2VGQ A;  2L9M A;  2KM6 A;  4FH0 A;  2BBZ A;  4JQW A;  4M9X A;  1E3Y A;  2G7R A;  2YGS A;  2N00 A;  2NZ7 A;  2N1F A;  4EWI A;  1UCP A;  2N7Z A;  2MJM A;  2MS8 A;  2IB1 A;  1DDF A;  2L6A A;  1A1W A;  1Z6T A;  3EZQ B;  1WXP A;  2DBH A;  2MN4 A;  2F1S A;  3QF2 A;  2DO9 A;  2MB9 A;  1N3K A;  3YGS C;  4E9M A;  1CY5 A;  2B1W A;  2D96 A;  2O71 A;  4NQK A;  3MOP G;  1YGO A;  4RHW A;  2BBR A;  1NGR A;  2DBD A;  3J6J A;  1D2Z A;  3YGS P;  2LWE A;  1ICH A;  2LS7 A;  3CRD A;  2A5Y B;  3CL3 A;  2MPC A;  2A9I A;  2YQF A;  1C15 A;  4F44 A;  4P4H A;  2NSN A;  2OF5 H;  4P4H I;  4A2W A;  4O6X A;  3KAT A;  4UZ0 A;  4M9Z A;  4N1J A;  4D8O A;  4N1L A;  1WMG A;  4N1K A;  2DBF A;  4O9L A;  3T6P A;  4QOB A;  2DBG A;  3LQR A;  4ZBW A;  2MS7 A;  3EZQ A;  4IZA B;  4I16 A;  4M9S A;  2M5V A;  4DWN A;  2GF5 A;  4A2Q A;  1D2Z B;  2N83 A;  4LWD A;  2XV9 A;  1WH4 A;  2LWD A;  4JUP A;  3MOP A;  2YU0 A;  2N97 A;  4RHW E;  1FAD A;  1PN5 A;  3J63 A;  1DGN A;  3LQQ A;  2P1H A;  1E41 A;  2HM2 Q;  1CWW A;  4IZ5 E;  3MOP K;  2YVI A;  4O7Q A;  2KN6 A;  4O9F A;  4IZ7 B;  2NAQ A;  2N80 A;  1A1Z A; 
#chains in the Genus database with same CATH homology
 4F42 A;  2OF5 A;  2VGQ A;  2L9M A;  2KM6 A;  4FH0 A;  2BBZ A;  4JQW A;  4M9X A;  1E3Y A;  2G7R A;  2YGS A;  2N00 A;  2NZ7 A;  2N1F A;  4EWI A;  1UCP A;  2N7Z A;  2MJM A;  2MS8 A;  2IB1 A;  1DDF A;  2L6A A;  1A1W A;  1Z6T A;  3EZQ B;  1WXP A;  2DBH A;  2MN4 A;  2F1S A;  3QF2 A;  2DO9 A;  2MB9 A;  1N3K A;  3YGS C;  4E9M A;  1CY5 A;  2B1W A;  2D96 A;  2O71 A;  4NQK A;  3MOP G;  1YGO A;  4RHW A;  2BBR A;  1NGR A;  2DBD A;  3J6J A;  1D2Z A;  3YGS P;  2LWE A;  1ICH A;  2LS7 A;  3CRD A;  2A5Y B;  3CL3 A;  2MPC A;  2A9I A;  2YQF A;  1C15 A;  4F44 A;  4P4H A;  2NSN A;  2OF5 H;  4P4H I;  4A2W A;  4O6X A;  3KAT A;  4UZ0 A;  4M9Z A;  4N1J A;  4D8O A;  4N1L A;  1WMG A;  4N1K A;  2DBF A;  4O9L A;  3T6P A;  4QOB A;  2DBG A;  3LQR A;  4ZBW A;  2MS7 A;  3EZQ A;  4IZA B;  4I16 A;  4M9S A;  2M5V A;  4DWN A;  2GF5 A;  4A2Q A;  1D2Z B;  2N83 A;  4LWD A;  2XV9 A;  1WH4 A;  2LWD A;  4JUP A;  3MOP A;  2YU0 A;  2N97 A;  4RHW E;  1FAD A;  1PN5 A;  3J63 A;  1DGN A;  3LQQ A;  2P1H A;  1E41 A;  2HM2 Q;  1CWW A;  4IZ5 E;  3MOP K;  2YVI A;  4O7Q A;  2KN6 A;  4O9F A;  4IZ7 B;  2NAQ A;  2N80 A;  1A1Z A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...