2MS7A

High-resolution solid-state nmr structure of the helical signal transduction filament mavs card
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
102
structure length
102
Chain Sequence
GSMPFAEDKTYKYICRNFSNFCNVDVVEILPYLPCLTARDQDRLRATCTLSGNRDTLWHLFNTLQRRPGWVEYFIAALRGCELVDLADEVASVYQSYQPRTS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure determination of helical filaments by solid-state NMR spectroscopy.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Mitochondrial antiviral-signaling protein
total genus 26
structure length 102
sequence length 102
chains with identical sequence B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U
ec nomenclature
pdb deposition date 2014-07-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF16739 CARD_2 Caspase recruitment domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 2ms7A00
3J63A 4O9LA 2KM6A 1E41A 2OF5A 4D8OA 4M9XA 3EZQA 1DDFA 4QOBA 4RHWA 2YQFA 4NQKA 1CY5A 1UCPA 2IB1A 1D2ZB 2N7ZA 1E3YA 2YVIA 2DBFA 2NAQA 2D96A 1A1WA 1N3KA 2F1SA 2MB9A 2DBDA 4O6XA 3KATA 1ICHA 1CWWA 2BBRA 3MOPG 2DBGA 2A5YB 1FADA 2NSNA 4N1LA 4M9ZA 1WXPA 4JUPA 2DO9A 4A2QA 1DGNA 4RHWE 2MS8A 2L6AA 2N00A 2G7RA 1NGRA 4LWDA 2LWEA 4F42A 4N1KA 4P4HI 4DWNA 3LQQA 3MOPK 2KN6A 4O9FA 2N1FA 4IZ5E 2L9MA 2N97A 3CRDA 2YGSA 2N80A 2O71A 3EZQB 2DBHA 2OF5H 2GF5A 4FH0A 1D2ZA 3CL3A 4P4HA 3MOPA 2VGQA 3T6PA 2LS7A 3YGSC 4I16A 4M9SA 2B1WA 2HM2Q 2MPCA 2YU0A 4ZBWA 1Z6TA 2BBZA 4E9MA 4IZAB 3LQRA 4EWIA 3YGSP 2N83A 4UZ0A 4A2WA 4O7QA 4IZ7B 1WH4A 2P1HA 1C15A 3QF2A 2A9IA 1YGOA 2NZ7A 2MN4A 4JQWA 2MS7A 4F44A 1A1ZA 2M5VA 2LWDA 3J6JA 1PN5A 1WMGA 4N1JA
chains in the Genus database with same CATH superfamily
3J63A 4O9LA 2KM6A 1E41A 2OF5A 4D8OA 4M9XA 3EZQA 1DDFA 4QOBA 4RHWA 2YQFA 4NQKA 1CY5A 1UCPA 2IB1A 1D2ZB 2N7ZA 1E3YA 2YVIA 2DBFA 2NAQA 2D96A 1A1WA 1N3KA 2F1SA 2MB9A 2DBDA 4O6XA 3KATA 1ICHA 1CWWA 2BBRA 3MOPG 2DBGA 2A5YB 1FADA 2NSNA 4N1LA 4M9ZA 1WXPA 4JUPA 2DO9A 4A2QA 1DGNA 4RHWE 2MS8A 2L6AA 2N00A 2G7RA 1NGRA 4LWDA 2LWEA 4F42A 4N1KA 4P4HI 4DWNA 3LQQA 3MOPK 2KN6A 4O9FA 2N1FA 4IZ5E 2L9MA 2N97A 3CRDA 2YGSA 2N80A 2O71A 3EZQB 2DBHA 2OF5H 2GF5A 4FH0A 1D2ZA 3CL3A 4P4HA 2MJMA 3MOPA 2VGQA 3T6PA 2LS7A 3YGSC 4I16A 4M9SA 2B1WA 2HM2Q 2MPCA 2YU0A 4ZBWA 1Z6TA 2BBZA 4E9MA 4IZAB 3LQRA 4EWIA 3YGSP 2N83A 4UZ0A 4A2WA 4O7QA 4IZ7B 1WH4A 2P1HA 1C15A 2A9IA 1YGOA 3QF2A 2NZ7A 2MN4A 4JQWA 2MS7A 4F44A 1A1ZA 2M5VA 2LWDA 3J6JA 1PN5A 2XV9A 1WMGA 4N1JA
chains in the Genus database with same CATH topology
3J63A 4O9LA 2KM6A 1E41A 2OF5A 4D8OA 4M9XA 3EZQA 1DDFA 4QOBA 4RHWA 2YQFA 4NQKA 1CY5A 1UCPA 2IB1A 1D2ZB 2N7ZA 1E3YA 2YVIA 2DBFA 2NAQA 2D96A 1A1WA 1N3KA 2F1SA 2MB9A 2DBDA 4O6XA 3KATA 1ICHA 1CWWA 2BBRA 3MOPG 2DBGA 2A5YB 1FADA 2NSNA 4N1LA 4M9ZA 1WXPA 4JUPA 2DO9A 4A2QA 1DGNA 4RHWE 2MS8A 2L6AA 2N00A 2G7RA 1NGRA 4LWDA 2LWEA 4F42A 4N1KA 4P4HI 4DWNA 3LQQA 3MOPK 2KN6A 4O9FA 2N1FA 4IZ5E 2L9MA 2N97A 3CRDA 2YGSA 2N80A 2O71A 3EZQB 2DBHA 2OF5H 2GF5A 4FH0A 1D2ZA 3CL3A 4P4HA 2MJMA 3MOPA 2VGQA 3T6PA 2LS7A 3YGSC 4I16A 4M9SA 2B1WA 2HM2Q 2MPCA 2YU0A 4ZBWA 1Z6TA 2BBZA 4E9MA 4IZAB 3LQRA 4EWIA 3YGSP 2N83A 4UZ0A 4A2WA 4O7QA 4IZ7B 1WH4A 2P1HA 1C15A 2A9IA 1YGOA 3QF2A 2NZ7A 2MN4A 4JQWA 2MS7A 4F44A 1A1ZA 2M5VA 2LWDA 3J6JA 1PN5A 2XV9A 1WMGA 4N1JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3J63 A;  4O9L A;  2KM6 A;  1E41 A;  2OF5 A;  4D8O A;  4M9X A;  3EZQ A;  1DDF A;  4QOB A;  4RHW A;  2YQF A;  4NQK A;  1CY5 A;  1UCP A;  2IB1 A;  1D2Z B;  2N7Z A;  1E3Y A;  2YVI A;  2DBF A;  2NAQ A;  2D96 A;  1A1W A;  1N3K A;  2F1S A;  2MB9 A;  2DBD A;  4O6X A;  3KAT A;  1ICH A;  1CWW A;  2BBR A;  3MOP G;  2DBG A;  2A5Y B;  1FAD A;  2NSN A;  4N1L A;  4M9Z A;  1WXP A;  4JUP A;  2DO9 A;  4A2Q A;  1DGN A;  4RHW E;  2MS8 A;  2L6A A;  2N00 A;  2G7R A;  1NGR A;  4LWD A;  2LWE A;  4F42 A;  4N1K A;  4P4H I;  4DWN A;  3LQQ A;  3MOP K;  2KN6 A;  4O9F A;  2N1F A;  4IZ5 E;  2L9M A;  2N97 A;  3CRD A;  2YGS A;  2N80 A;  2O71 A;  3EZQ B;  2DBH A;  2OF5 H;  2GF5 A;  4FH0 A;  1D2Z A;  3CL3 A;  4P4H A;  3MOP A;  2VGQ A;  3T6P A;  2LS7 A;  3YGS C;  4I16 A;  4M9S A;  2B1W A;  2HM2 Q;  2MPC A;  2YU0 A;  4ZBW A;  1Z6T A;  2BBZ A;  4E9M A;  4IZA B;  3LQR A;  4EWI A;  3YGS P;  2N83 A;  4UZ0 A;  4A2W A;  4O7Q A;  4IZ7 B;  1WH4 A;  2P1H A;  1C15 A;  3QF2 A;  2A9I A;  1YGO A;  2NZ7 A;  2MN4 A;  4JQW A;  2MS7 A;  4F44 A;  1A1Z A;  2M5V A;  2LWD A;  3J6J A;  1PN5 A;  1WMG A;  4N1J A; 
#chains in the Genus database with same CATH topology
 3J63 A;  4O9L A;  2KM6 A;  1E41 A;  2OF5 A;  4D8O A;  4M9X A;  3EZQ A;  1DDF A;  4QOB A;  4RHW A;  2YQF A;  4NQK A;  1CY5 A;  1UCP A;  2IB1 A;  1D2Z B;  2N7Z A;  1E3Y A;  2YVI A;  2DBF A;  2NAQ A;  2D96 A;  1A1W A;  1N3K A;  2F1S A;  2MB9 A;  2DBD A;  4O6X A;  3KAT A;  1ICH A;  1CWW A;  2BBR A;  3MOP G;  2DBG A;  2A5Y B;  1FAD A;  2NSN A;  4N1L A;  4M9Z A;  1WXP A;  4JUP A;  2DO9 A;  4A2Q A;  1DGN A;  4RHW E;  2MS8 A;  2L6A A;  2N00 A;  2G7R A;  1NGR A;  4LWD A;  2LWE A;  4F42 A;  4N1K A;  4P4H I;  4DWN A;  3LQQ A;  3MOP K;  2KN6 A;  4O9F A;  2N1F A;  4IZ5 E;  2L9M A;  2N97 A;  3CRD A;  2YGS A;  2N80 A;  2O71 A;  3EZQ B;  2DBH A;  2OF5 H;  2GF5 A;  4FH0 A;  1D2Z A;  3CL3 A;  4P4H A;  2MJM A;  3MOP A;  2VGQ A;  3T6P A;  2LS7 A;  3YGS C;  4I16 A;  4M9S A;  2B1W A;  2HM2 Q;  2MPC A;  2YU0 A;  4ZBW A;  1Z6T A;  2BBZ A;  4E9M A;  4IZA B;  3LQR A;  4EWI A;  3YGS P;  2N83 A;  4UZ0 A;  4A2W A;  4O7Q A;  4IZ7 B;  1WH4 A;  2P1H A;  1C15 A;  2A9I A;  1YGO A;  3QF2 A;  2NZ7 A;  2MN4 A;  4JQW A;  2MS7 A;  4F44 A;  1A1Z A;  2M5V A;  2LWD A;  3J6J A;  1PN5 A;  2XV9 A;  1WMG A;  4N1J A; 
#chains in the Genus database with same CATH homology
 3J63 A;  4O9L A;  2KM6 A;  1E41 A;  2OF5 A;  4D8O A;  4M9X A;  3EZQ A;  1DDF A;  4QOB A;  4RHW A;  2YQF A;  4NQK A;  1CY5 A;  1UCP A;  2IB1 A;  1D2Z B;  2N7Z A;  1E3Y A;  2YVI A;  2DBF A;  2NAQ A;  2D96 A;  1A1W A;  1N3K A;  2F1S A;  2MB9 A;  2DBD A;  4O6X A;  3KAT A;  1ICH A;  1CWW A;  2BBR A;  3MOP G;  2DBG A;  2A5Y B;  1FAD A;  2NSN A;  4N1L A;  4M9Z A;  1WXP A;  4JUP A;  2DO9 A;  4A2Q A;  1DGN A;  4RHW E;  2MS8 A;  2L6A A;  2N00 A;  2G7R A;  1NGR A;  4LWD A;  2LWE A;  4F42 A;  4N1K A;  4P4H I;  4DWN A;  3LQQ A;  3MOP K;  2KN6 A;  4O9F A;  2N1F A;  4IZ5 E;  2L9M A;  2N97 A;  3CRD A;  2YGS A;  2N80 A;  2O71 A;  3EZQ B;  2DBH A;  2OF5 H;  2GF5 A;  4FH0 A;  1D2Z A;  3CL3 A;  4P4H A;  2MJM A;  3MOP A;  2VGQ A;  3T6P A;  2LS7 A;  3YGS C;  4I16 A;  4M9S A;  2B1W A;  2HM2 Q;  2MPC A;  2YU0 A;  4ZBW A;  1Z6T A;  2BBZ A;  4E9M A;  4IZA B;  3LQR A;  4EWI A;  3YGS P;  2N83 A;  4UZ0 A;  4A2W A;  4O7Q A;  4IZ7 B;  1WH4 A;  2P1H A;  1C15 A;  2A9I A;  1YGO A;  3QF2 A;  2NZ7 A;  2MN4 A;  4JQW A;  2MS7 A;  4F44 A;  1A1Z A;  2M5V A;  2LWD A;  3J6J A;  1PN5 A;  2XV9 A;  1WMG A;  4N1J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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