2N97A

Dd homodimer
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
94
structure length
94
Chain Sequence
GLYSSLPPAKREEVEKLLNGSAGDTWRHLAGELGYQPEHIDSFTHEACPVRALLASWATQDSATLDALLAALRRIQRADLVESLCSESTATSPV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis of death domain signaling in the p75 neurotrophin receptor
pubmed doi rcsb
source organism Homo sapiens
molecule tags Signaling protein
molecule keywords Tumor necrosis factor receptor superfamily member 16
total genus 29
structure length 94
sequence length 94
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-11-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00531 Death Death domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 2n97A00
4A2WA 2M5VA 4O6XA 2LWEA 1ICHA 4A2QA 3MOPA 2A9IA 2DBHA 2MS7A 4FH0A 4D8OA 2BBZA 4M9ZA 4RHWE 2B1WA 2GF5A 1DDFA 4N1LA 2IB1A 1YGOA 4E9MA 2L9MA 4M9SA 4O7QA 2MS8A 4I16A 4IZAB 4JUPA 2VGQA 4M9XA 1D2ZA 2N80A 4P4HI 3MOPK 1Z6TA 2YU0A 3YGSP 2N00A 2F1SA 1N3KA 3J63A 4N1JA 2KN6A 1E41A 4N1KA 4O9FA 4NQKA 4F44A 4O9LA 2G7RA 2P1HA 4QOBA 4DWNA 1WMGA 3KATA 2N83A 4EWIA 4F42A 1A1ZA 4JQWA 1D2ZB 2DBDA 4LWDA 1UCPA 2A5YB 3J6JA 1CY5A 3EZQB 1A1WA 2N7ZA 4UZ0A 2NAQA 3T6PA 1C15A 2N1FA 4IZ5E 2L6AA 2DO9A 2NZ7A 2BBRA 4ZBWA 3CL3A 2YGSA 4RHWA 3CRDA 1FADA 2LS7A 1NGRA 1WXPA 1E3YA 2DBGA 2D96A 2MB9A 2MN4A 2OF5H 2LWDA 3LQQA 3QF2A 2O71A 1PN5A 1CWWA 3LQRA 2YVIA 2MPCA 3EZQA 2DBFA 1WH4A 4IZ7B 1DGNA 3MOPG 3YGSC 2NSNA 2HM2Q 2YQFA 4P4HA 2N97A 2KM6A 2OF5A
chains in the Genus database with same CATH superfamily
4A2WA 2M5VA 4O6XA 2LWEA 1ICHA 4A2QA 3MOPA 2A9IA 2DBHA 2MS7A 2MJMA 4FH0A 4D8OA 2BBZA 4M9ZA 4RHWE 2B1WA 2GF5A 1DDFA 4N1LA 2IB1A 1YGOA 4E9MA 2L9MA 4M9SA 4O7QA 2MS8A 4I16A 4IZAB 4JUPA 2VGQA 4M9XA 1D2ZA 2N80A 4P4HI 3MOPK 1Z6TA 2YU0A 3YGSP 2N00A 2F1SA 1N3KA 3J63A 4N1JA 2KN6A 1E41A 4N1KA 4O9FA 4NQKA 4F44A 4O9LA 2G7RA 2P1HA 4QOBA 4DWNA 1WMGA 3KATA 2N83A 4EWIA 4F42A 1A1ZA 4JQWA 1D2ZB 2DBDA 4LWDA 1UCPA 2A5YB 3J6JA 1CY5A 3EZQB 1A1WA 2N7ZA 4UZ0A 2NAQA 3T6PA 1C15A 2N1FA 4IZ5E 2L6AA 2DO9A 2NZ7A 2BBRA 4ZBWA 3CL3A 2YGSA 4RHWA 3CRDA 1FADA 2LS7A 1NGRA 1WXPA 1E3YA 2DBGA 2D96A 2MB9A 2MN4A 2OF5H 2LWDA 3LQQA 3QF2A 2O71A 1PN5A 1CWWA 3LQRA 2YVIA 2MPCA 3EZQA 2DBFA 1WH4A 4IZ7B 1DGNA 3MOPG 2XV9A 3YGSC 2NSNA 2HM2Q 2YQFA 4P4HA 2N97A 2KM6A 2OF5A
chains in the Genus database with same CATH topology
4A2WA 2M5VA 4O6XA 2LWEA 1ICHA 4A2QA 3MOPA 2A9IA 2DBHA 2MS7A 2MJMA 4FH0A 4D8OA 2BBZA 4M9ZA 4RHWE 2B1WA 2GF5A 1DDFA 4N1LA 2IB1A 1YGOA 4E9MA 2L9MA 4M9SA 4O7QA 2MS8A 4I16A 4IZAB 4JUPA 2VGQA 4M9XA 1D2ZA 2N80A 4P4HI 3MOPK 1Z6TA 2YU0A 3YGSP 2N00A 2F1SA 1N3KA 3J63A 4N1JA 2KN6A 1E41A 4N1KA 4O9FA 4NQKA 4F44A 4O9LA 2G7RA 2P1HA 4QOBA 4DWNA 1WMGA 3KATA 2N83A 4EWIA 4F42A 1A1ZA 4JQWA 1D2ZB 2DBDA 4LWDA 1UCPA 2A5YB 3J6JA 1CY5A 3EZQB 1A1WA 2N7ZA 4UZ0A 2NAQA 3T6PA 1C15A 2N1FA 4IZ5E 2L6AA 2DO9A 2NZ7A 2BBRA 4ZBWA 3CL3A 2YGSA 4RHWA 3CRDA 1FADA 2LS7A 1NGRA 1WXPA 1E3YA 2DBGA 2D96A 2MB9A 2MN4A 2OF5H 2LWDA 3LQQA 3QF2A 2O71A 1PN5A 1CWWA 3LQRA 2YVIA 2MPCA 3EZQA 2DBFA 1WH4A 4IZ7B 1DGNA 3MOPG 2XV9A 3YGSC 2NSNA 2HM2Q 2YQFA 4P4HA 2N97A 2KM6A 2OF5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A2W A;  2M5V A;  4O6X A;  2LWE A;  1ICH A;  4A2Q A;  3MOP A;  2A9I A;  2DBH A;  2MS7 A;  4FH0 A;  4D8O A;  2BBZ A;  4M9Z A;  4RHW E;  2B1W A;  2GF5 A;  1DDF A;  4N1L A;  2IB1 A;  1YGO A;  4E9M A;  2L9M A;  4M9S A;  4O7Q A;  2MS8 A;  4I16 A;  4IZA B;  4JUP A;  2VGQ A;  4M9X A;  1D2Z A;  2N80 A;  4P4H I;  3MOP K;  1Z6T A;  2YU0 A;  3YGS P;  2N00 A;  2F1S A;  1N3K A;  3J63 A;  4N1J A;  2KN6 A;  1E41 A;  4N1K A;  4O9F A;  4NQK A;  4F44 A;  4O9L A;  2G7R A;  2P1H A;  4QOB A;  4DWN A;  1WMG A;  3KAT A;  2N83 A;  4EWI A;  4F42 A;  1A1Z A;  4JQW A;  1D2Z B;  2DBD A;  4LWD A;  1UCP A;  2A5Y B;  3J6J A;  1CY5 A;  3EZQ B;  1A1W A;  2N7Z A;  4UZ0 A;  2NAQ A;  3T6P A;  1C15 A;  2N1F A;  4IZ5 E;  2L6A A;  2DO9 A;  2NZ7 A;  2BBR A;  4ZBW A;  3CL3 A;  2YGS A;  4RHW A;  3CRD A;  1FAD A;  2LS7 A;  1NGR A;  1WXP A;  1E3Y A;  2DBG A;  2D96 A;  2MB9 A;  2MN4 A;  2OF5 H;  2LWD A;  3LQQ A;  3QF2 A;  2O71 A;  1PN5 A;  1CWW A;  3LQR A;  2YVI A;  2MPC A;  3EZQ A;  2DBF A;  1WH4 A;  4IZ7 B;  1DGN A;  3MOP G;  3YGS C;  2NSN A;  2HM2 Q;  2YQF A;  4P4H A;  2N97 A;  2KM6 A;  2OF5 A; 
#chains in the Genus database with same CATH topology
 4A2W A;  2M5V A;  4O6X A;  2LWE A;  1ICH A;  4A2Q A;  3MOP A;  2A9I A;  2DBH A;  2MS7 A;  2MJM A;  4FH0 A;  4D8O A;  2BBZ A;  4M9Z A;  4RHW E;  2B1W A;  2GF5 A;  1DDF A;  4N1L A;  2IB1 A;  1YGO A;  4E9M A;  2L9M A;  4M9S A;  4O7Q A;  2MS8 A;  4I16 A;  4IZA B;  4JUP A;  2VGQ A;  4M9X A;  1D2Z A;  2N80 A;  4P4H I;  3MOP K;  1Z6T A;  2YU0 A;  3YGS P;  2N00 A;  2F1S A;  1N3K A;  3J63 A;  4N1J A;  2KN6 A;  1E41 A;  4N1K A;  4O9F A;  4NQK A;  4F44 A;  4O9L A;  2G7R A;  2P1H A;  4QOB A;  4DWN A;  1WMG A;  3KAT A;  2N83 A;  4EWI A;  4F42 A;  1A1Z A;  4JQW A;  1D2Z B;  2DBD A;  4LWD A;  1UCP A;  2A5Y B;  3J6J A;  1CY5 A;  3EZQ B;  1A1W A;  2N7Z A;  4UZ0 A;  2NAQ A;  3T6P A;  1C15 A;  2N1F A;  4IZ5 E;  2L6A A;  2DO9 A;  2NZ7 A;  2BBR A;  4ZBW A;  3CL3 A;  2YGS A;  4RHW A;  3CRD A;  1FAD A;  2LS7 A;  1NGR A;  1WXP A;  1E3Y A;  2DBG A;  2D96 A;  2MB9 A;  2MN4 A;  2OF5 H;  2LWD A;  3LQQ A;  3QF2 A;  2O71 A;  1PN5 A;  1CWW A;  3LQR A;  2YVI A;  2MPC A;  3EZQ A;  2DBF A;  1WH4 A;  4IZ7 B;  1DGN A;  3MOP G;  2XV9 A;  3YGS C;  2NSN A;  2HM2 Q;  2YQF A;  4P4H A;  2N97 A;  2KM6 A;  2OF5 A; 
#chains in the Genus database with same CATH homology
 4A2W A;  2M5V A;  4O6X A;  2LWE A;  1ICH A;  4A2Q A;  3MOP A;  2A9I A;  2DBH A;  2MS7 A;  2MJM A;  4FH0 A;  4D8O A;  2BBZ A;  4M9Z A;  4RHW E;  2B1W A;  2GF5 A;  1DDF A;  4N1L A;  2IB1 A;  1YGO A;  4E9M A;  2L9M A;  4M9S A;  4O7Q A;  2MS8 A;  4I16 A;  4IZA B;  4JUP A;  2VGQ A;  4M9X A;  1D2Z A;  2N80 A;  4P4H I;  3MOP K;  1Z6T A;  2YU0 A;  3YGS P;  2N00 A;  2F1S A;  1N3K A;  3J63 A;  4N1J A;  2KN6 A;  1E41 A;  4N1K A;  4O9F A;  4NQK A;  4F44 A;  4O9L A;  2G7R A;  2P1H A;  4QOB A;  4DWN A;  1WMG A;  3KAT A;  2N83 A;  4EWI A;  4F42 A;  1A1Z A;  4JQW A;  1D2Z B;  2DBD A;  4LWD A;  1UCP A;  2A5Y B;  3J6J A;  1CY5 A;  3EZQ B;  1A1W A;  2N7Z A;  4UZ0 A;  2NAQ A;  3T6P A;  1C15 A;  2N1F A;  4IZ5 E;  2L6A A;  2DO9 A;  2NZ7 A;  2BBR A;  4ZBW A;  3CL3 A;  2YGS A;  4RHW A;  3CRD A;  1FAD A;  2LS7 A;  1NGR A;  1WXP A;  1E3Y A;  2DBG A;  2D96 A;  2MB9 A;  2MN4 A;  2OF5 H;  2LWD A;  3LQQ A;  3QF2 A;  2O71 A;  1PN5 A;  1CWW A;  3LQR A;  2YVI A;  2MPC A;  3EZQ A;  2DBF A;  1WH4 A;  4IZ7 B;  1DGN A;  3MOP G;  2XV9 A;  3YGS C;  2NSN A;  2HM2 Q;  2YQF A;  4P4H A;  2N97 A;  2KM6 A;  2OF5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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