2NGRB

Transition state complex for gtp hydrolysis by cdc42: comparisons of the high resolution structures for cdc42 bound to the active and catalytically compromised forms of the cdc42-gap.
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
196
structure length
196
Chain Sequence
LPNQQFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFARSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQVLQTLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELFP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords PROTEIN (GTP BINDING PROTEIN (G25K))
publication title Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP.
pubmed doi rcsb
source organism Homo sapiens
total genus 71
structure length 196
sequence length 196
ec nomenclature
pdb deposition date 1998-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00620 RhoGAP RhoGAP domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.555.10 Mainly Alpha Orthogonal Bundle Phosphatidylinositol 3-kinase; Chain A Rho GTPase activation protein 2ngrB00
3FK2A 1XA6A 2QV2A 3IUGA 3BYIA 2MBGA 3EAPA 5JD0A 1OW3A 3CXLA 2XS6A 1PBWA 1F7CA 3MSXB 2OSAA 5C2JA 1TX4A 1GRNB 2NGRB 2EE4A 5C5SA 3W6RA 5JCPA 2EE5A 1AM4A 3WPSA 3KUQA 3QISA 1RGPA 3WPQA 2OVJA 5HPYA 5IRCA
chains in the Genus database with same CATH superfamily
3FK2A 1XA6A 2QV2A 3IUGA 3BYIA 2MBGA 3EAPA 5JD0A 1OW3A 3CXLA 2XS6A 1PBWA 1F7CA 3MSXB 2OSAA 5C2JA 1TX4A 1GRNB 2NGRB 2EE4A 5C5SA 3W6RA 5JCPA 2EE5A 1AM4A 3WPSA 3KUQA 3QISA 1RGPA 3WPQA 2OVJA 5HPYA 5IRCA
chains in the Genus database with same CATH topology
3FK2A 1XA6A 2QV2A 3IUGA 3BYIA 2MBGA 3EAPA 5JD0A 1OW3A 3CXLA 2XS6A 1PBWA 1F7CA 3MSXB 2OSAA 5C2JA 1TX4A 1GRNB 2NGRB 2EE4A 5C5SA 3W6RA 5JCPA 2EE5A 1AM4A 3WPSA 3KUQA 3QISA 1RGPA 3WPQA 2OVJA 5HPYA 5IRCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FK2 A;  1XA6 A;  2QV2 A;  3IUG A;  3BYI A;  2MBG A;  3EAP A;  5JD0 A;  1OW3 A;  3CXL A;  2XS6 A;  1PBW A;  1F7C A;  3MSX B;  2OSA A;  5C2J A;  1TX4 A;  1GRN B;  2NGR B;  2EE4 A;  5C5S A;  3W6R A;  5JCP A;  2EE5 A;  1AM4 A;  3WPS A;  3KUQ A;  3QIS A;  1RGP A;  3WPQ A;  2OVJ A;  5HPY A;  5IRC A; 
#chains in the Genus database with same CATH topology
 3FK2 A;  1XA6 A;  2QV2 A;  3IUG A;  3BYI A;  2MBG A;  3EAP A;  5JD0 A;  1OW3 A;  3CXL A;  2XS6 A;  1PBW A;  1F7C A;  3MSX B;  2OSA A;  5C2J A;  1TX4 A;  1GRN B;  2NGR B;  2EE4 A;  5C5S A;  3W6R A;  5JCP A;  2EE5 A;  1AM4 A;  3WPS A;  3KUQ A;  3QIS A;  1RGP A;  3WPQ A;  2OVJ A;  5HPY A;  5IRC A; 
#chains in the Genus database with same CATH homology
 3FK2 A;  1XA6 A;  2QV2 A;  3IUG A;  3BYI A;  2MBG A;  3EAP A;  5JD0 A;  1OW3 A;  3CXL A;  2XS6 A;  1PBW A;  1F7C A;  3MSX B;  2OSA A;  5C2J A;  1TX4 A;  1GRN B;  2NGR B;  2EE4 A;  5C5S A;  3W6R A;  5JCP A;  2EE5 A;  1AM4 A;  3WPS A;  3KUQ A;  3QIS A;  1RGP A;  3WPQ A;  2OVJ A;  5HPY A;  5IRC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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