2NQVA

Moea d228a
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
405
structure length
405
Chain Sequence
LMSLDTALNEMLSRVTPLTAQETLPLVQCFGRILASDVVSPLDVPGFDNSAMDGYAVRLADIASGQPLPVAGKSFAGQPYHGEWPAGTCIRIMTGAPVPEGCEAVVMQEQTEQMDNGVRFTAEVRSGQNIRRRGEDISAGAVVFPAGTRLTTAELPVIASLGIAEVPVIRKVRVALFSTGDELQLPGQPLGDGQIYDTNRLAVHLMLEQLGCEVINLGIIRADPHALRAAFIEADSQADVVISSGGVSVGEADYTKTILEELGEIAFWKLAIKPGKPFAFGKLSNSWFCGLPGNPVSATLTFYQLVQPLLAKLSGNTASGLPARQRVRTASRLKKTPGRLDFQRGVLQRNADGELEVTTTGHQGSHIFSSFSLGNCFIVLERDRGNVEVGEWVEVEPFNALFGGL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutational Analysis of Escherichia coli MoeA: Two Functional Activities Map to the Active Site Cleft.
pubmed doi rcsb
molecule tags Biosynthetic protein
source organism Escherichia coli
molecule keywords Molybdopterin biosynthesis protein moeA
total genus 91
structure length 405
sequence length 405
chains with identical sequence B
ec nomenclature ec 2.10.1.1: Molybdopterin molybdotransferase.
pdb deposition date 2006-10-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00994 MoCF_biosynth Probable molybdopterin binding domain
A PF03453 MoeA_N MoeA N-terminal region (domain I and II)
A PF03454 MoeA_C MoeA C-terminal region (domain IV)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.340.10 Mainly Beta Beta Barrel Beta-clip MoeA, C-terminal, domain IV 2nqvA04
2.170.190.11 Mainly Beta Beta Complex Molybdopterin biosynthesis moeA protein; domain 3 Molybdopterin biosynthesis moea protein, domain 3. 2nqvA03
3.40.980.10 Alpha Beta 3-Layer(aba) Sandwich Molybdenum Cofactor Biosythetic Enzyme; Chain A MoaB/Mog-like domain 2nqvA01
3.90.105.10 Alpha Beta Alpha-Beta Complex Molybdopterin biosynthesis moea protein, domain 2 Molybdopterin biosynthesis moea protein, domain 2 2nqvA02
3IWTA 4UUXA 4TK1A 2G4RA 5ERQA 4PD0A 4U90A 1WU2A 2FU3A 1G8RA 1R2KA 1G8LA 4UUWA 3K6AA 4LHBA 2F7WA 2NRPA 1IHCA 5G2SA 4TWGA 5ERVA 1O8OA 1FC5A 4NWOA 2NQMA 2F7YA 4TK4A 1UZ5A 2NROA 4XCWA 1DI6A 3MCIA 5ERUA 1O8NA 2QQ1A 4CT8A 1MKZA 3MCHA 5ERSA 5G2RA 2NQQA 1DI7A 2IS8A 3KBQA 4CTAB 3TCRA 2X3LA 3MCJA 2FTSA 2NQRA 2PBQA 5ERRA 1UUXA 3PZYA 2G2CA 2NQVA 4PD1A 1XI8A 3OI9A 4TK3A 2NQKA 4CT9A 4U91A 1O8QA 2NQSA 1EAVA 1T3EA 2NQUA 5ERTA 1JLJA 3RFQA 4CTAA 2NRSA 4UOCA 1UUYA 1Y5EA 2NQNA
chains in the Genus database with same CATH superfamily
3IWTA 4UUXA 4TK1A 2G4RA 5ERQA 4PD0A 4U90A 1WU2A 2FU3A 1G8RA 1R2KA 1G8LA 1HQMD 4UUWA 3K6AA 4LHBA 2F7WA 2NRPA 1IHCA 1YZYA 5G2SA 4TWGA 5ERVA 1O8OA 1FC5A 1I6VD 4NWOA 2NQMA 2F7YA 4TK4A 1UZ5A 5DMHA 2NROA 4XCWA 1DI6A 3MCIA 5ERUA 1O8NA 2QQ1A 4CT8A 1MKZA 4NWBA 3MCHA 5ERSA 5G2RA 2NQQA 1DI7A 2IS8A 3KBQA 4CTAB 3DQQA 3TCRA 2X3LA 5D8HB 3MCJA 2FTSA 1IW7D 2NQRA 2PBQA 5ERRA 1UUXA 3PZYA 3JSYA 2G2CA 2NQVA 4PD1A 1XI8A 3OI9A 4TK3A 2NQKA 4CT9A 4U91A 1O8QA 2NQSA 1EAVA 1T3EA 2NQUA 5ERTA 1JLJA 3RFQA 4CTAA 5D6GA 2NRSA 4UOCA 1UUYA 1Y5EA 2NQNA
chains in the Genus database with same CATH topology
3IWTA 4UUXA 4TK1A 2G4RA 5ERQA 4PD0A 4U90A 1WU2A 2FU3A 1G8RA 1R2KA 1G8LA 1HQMD 4UUWA 3K6AA 4LHBA 2F7WA 2NRPA 1IHCA 5G2SA 4TWGA 5ERVA 1O8OA 1FC5A 1I6VD 4NWOA 2NQMA 2F7YA 4TK4A 1UZ5A 2NROA 4XCWA 1DI6A 3MCIA 5ERUA 1O8NA 2QQ1A 4CT8A 1MKZA 4NWBA 3MCHA 5ERSA 5G2RA 2NQQA 1DI7A 2IS8A 3KBQA 4CTAB 3TCRA 2X3LA 5D8HB 3MCJA 2FTSA 1IW7D 2NQRA 2PBQA 5ERRA 1UUXA 3PZYA 3JSYA 2G2CA 2NQVA 4PD1A 1XI8A 3OI9A 4TK3A 2NQKA 4CT9A 4U91A 1O8QA 2NQSA 1EAVA 1T3EA 2NQUA 5ERTA 1JLJA 3RFQA 4CTAA 5D6GA 2NRSA 4UOCA 1UUYA 1Y5EA 2NQNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3IWT A;  4UUX A;  4TK1 A;  2G4R A;  5ERQ A;  4PD0 A;  4U90 A;  1WU2 A;  2FU3 A;  1G8R A;  1R2K A;  1G8L A;  4UUW A;  3K6A A;  4LHB A;  2F7W A;  2NRP A;  1IHC A;  5G2S A;  4TWG A;  5ERV A;  1O8O A;  1FC5 A;  4NWO A;  2NQM A;  2F7Y A;  4TK4 A;  1UZ5 A;  2NRO A;  4XCW A;  1DI6 A;  3MCI A;  5ERU A;  1O8N A;  2QQ1 A;  4CT8 A;  1MKZ A;  3MCH A;  5ERS A;  5G2R A;  2NQQ A;  1DI7 A;  2IS8 A;  3KBQ A;  4CTA B;  3TCR A;  2X3L A;  3MCJ A;  2FTS A;  2NQR A;  2PBQ A;  5ERR A;  1UUX A;  3PZY A;  2G2C A;  2NQV A;  4PD1 A;  1XI8 A;  3OI9 A;  4TK3 A;  2NQK A;  4CT9 A;  4U91 A;  1O8Q A;  2NQS A;  1EAV A;  1T3E A;  2NQU A;  5ERT A;  1JLJ A;  3RFQ A;  4CTA A;  2NRS A;  4UOC A;  1UUY A;  1Y5E A;  2NQN A; 
#chains in the Genus database with same CATH topology
 3IWT A;  4UUX A;  4TK1 A;  2G4R A;  5ERQ A;  4PD0 A;  4U90 A;  1WU2 A;  2FU3 A;  1G8R A;  1R2K A;  1G8L A;  1HQM D;  4UUW A;  3K6A A;  4LHB A;  2F7W A;  2NRP A;  1IHC A;  1YZY A;  5G2S A;  4TWG A;  5ERV A;  1O8O A;  1FC5 A;  1I6V D;  4NWO A;  2NQM A;  2F7Y A;  4TK4 A;  1UZ5 A;  5DMH A;  2NRO A;  4XCW A;  1DI6 A;  3MCI A;  5ERU A;  1O8N A;  2QQ1 A;  4CT8 A;  1MKZ A;  4NWB A;  3MCH A;  5ERS A;  5G2R A;  2NQQ A;  1DI7 A;  2IS8 A;  3KBQ A;  4CTA B;  3DQQ A;  3TCR A;  2X3L A;  5D8H B;  3MCJ A;  2FTS A;  1IW7 D;  2NQR A;  2PBQ A;  5ERR A;  1UUX A;  3PZY A;  3JSY A;  2G2C A;  2NQV A;  4PD1 A;  1XI8 A;  3OI9 A;  4TK3 A;  2NQK A;  4CT9 A;  4U91 A;  1O8Q A;  2NQS A;  1EAV A;  1T3E A;  2NQU A;  5ERT A;  1JLJ A;  3RFQ A;  4CTA A;  5D6G A;  2NRS A;  4UOC A;  1UUY A;  1Y5E A;  2NQN A; 
#chains in the Genus database with same CATH homology
 3IWT A;  4UUX A;  4TK1 A;  2G4R A;  5ERQ A;  4PD0 A;  4U90 A;  1WU2 A;  2FU3 A;  1G8R A;  1R2K A;  1G8L A;  1HQM D;  4UUW A;  3K6A A;  4LHB A;  2F7W A;  2NRP A;  1IHC A;  5G2S A;  4TWG A;  5ERV A;  1O8O A;  1FC5 A;  1I6V D;  4NWO A;  2NQM A;  2F7Y A;  4TK4 A;  1UZ5 A;  2NRO A;  4XCW A;  1DI6 A;  3MCI A;  5ERU A;  1O8N A;  2QQ1 A;  4CT8 A;  1MKZ A;  4NWB A;  3MCH A;  5ERS A;  5G2R A;  2NQQ A;  1DI7 A;  2IS8 A;  3KBQ A;  4CTA B;  3TCR A;  2X3L A;  5D8H B;  3MCJ A;  2FTS A;  1IW7 D;  2NQR A;  2PBQ A;  5ERR A;  1UUX A;  3PZY A;  3JSY A;  2G2C A;  2NQV A;  4PD1 A;  1XI8 A;  3OI9 A;  4TK3 A;  2NQK A;  4CT9 A;  4U91 A;  1O8Q A;  2NQS A;  1EAV A;  1T3E A;  2NQU A;  5ERT A;  1JLJ A;  3RFQ A;  4CTA A;  5D6G A;  2NRS A;  4UOC A;  1UUY A;  1Y5E A;  2NQN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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