2NRSA

Moea s371w
Total Genus 103
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
103
sequence length
403
structure length
403
Chain Sequence
LMSLDTALNEMLSRVTPLTAQETLPLVQCFGRILASDVVSPLDVPGFDNSAMDGYAVRLADIASGQPLPVAGKSFAGQPYHGEWPAGTCIRIMTGAPVPEGCEAVVMQEQTEQMDNGVRFTAEVRSGQNIRRRGEDISAGAVVFPAGTRLTTAELPVIASLGIAEVPVIRKVRVALFSTGDELQLPGQPLGDGQIYDTNRLAVHLMLEQLGCEVINLGIIRDDPHALRAAFIEADSQADVVISSGGVSVGEADYTKTILEELGEIAFWKLAIKPGKPFAFGKLSNSWFCGLPGNPVSATLTFYQLVQPLLAKLSGNTASGLPARQRVRTASRLKKTPGRLDFQRGVLQRNADGELEVTTTGHQGWHIFSSFSLGNCFIVLERDRGNVEVGEWVEVEPFNALFG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutational Analysis of Escherichia coli MoeA: Two Functional Activities Map to the Active Site Cleft.
pubmed doi rcsb
molecule tags Biosynthetic protein
source organism Escherichia coli
molecule keywords Molybdopterin biosynthesis protein moeA
total genus 103
structure length 403
sequence length 403
chains with identical sequence B
ec nomenclature ec 2.10.1.1: Molybdopterin molybdotransferase.
pdb deposition date 2006-11-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00994 MoCF_biosynth Probable molybdopterin binding domain
A PF03453 MoeA_N MoeA N-terminal region (domain I and II)
A PF03454 MoeA_C MoeA C-terminal region (domain IV)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.340.10 Mainly Beta Beta Barrel Beta-clip MoeA, C-terminal, domain IV 2nrsA04
2.170.190.11 Mainly Beta Beta Complex Molybdopterin biosynthesis moeA protein; domain 3 Molybdopterin biosynthesis moea protein, domain 3. 2nrsA03
3.40.980.10 Alpha Beta 3-Layer(aba) Sandwich Molybdenum Cofactor Biosythetic Enzyme; Chain A MoaB/Mog-like domain 2nrsA01
3.90.105.10 Alpha Beta Alpha-Beta Complex Molybdopterin biosynthesis moea protein, domain 2 Molybdopterin biosynthesis moea protein, domain 2 2nrsA02
1JLJA 4TK1A 3IWTA 3MCIA 4LHBA 2NQQA 3KBQA 4CT8A 5ERQA 1O8NA 2NQVA 4PD1A 4U91A 2NQRA 1O8OA 4UUXA 2PBQA 2X3LA 4UUWA 1DI6A 1G8RA 1DI7A 2QQ1A 2IS8A 5ERUA 2NQMA 1WU2A 5ERVA 1G8LA 4TWGA 2NRPA 1UZ5A 3MCHA 4PD0A 3MCJA 4UOCA 4XCWA 2NROA 3K6AA 2FU3A 1EAVA 1UUXA 3RFQA 5G2SA 2G4RA 2NQUA 4TK3A 5G2RA 1UUYA 4U90A 1Y5EA 3TCRA 5ERRA 1R2KA 2F7YA 3PZYA 1XI8A 1O8QA 2F7WA 4CT9A 4NWOA 4CTAA 5ERTA 2G2CA 2NQNA 2FTSA 5ERSA 2NQSA 1T3EA 1MKZA 2NQKA 1FC5A 2NRSA 4CTAB 3OI9A 4TK4A 1IHCA
chains in the Genus database with same CATH superfamily
1JLJA 4TK1A 3IWTA 3MCIA 3DQQA 4LHBA 2NQQA 3KBQA 4CT8A 5ERQA 3JSYA 1O8NA 2NQVA 4PD1A 4U91A 2NQRA 1O8OA 4UUXA 2PBQA 2X3LA 4UUWA 1DI6A 1G8RA 1DI7A 2QQ1A 2IS8A 5ERUA 2NQMA 1WU2A 5ERVA 1G8LA 4TWGA 5D8HB 2NRPA 1UZ5A 3MCHA 4PD0A 3MCJA 4UOCA 4XCWA 5D6GA 2NROA 3K6AA 2FU3A 1EAVA 1UUXA 3RFQA 5G2SA 2G4RA 2NQUA 4TK3A 5G2RA 1UUYA 4U90A 1IW7D 1Y5EA 1YZYA 3TCRA 5ERRA 1R2KA 2F7YA 3PZYA 1XI8A 1O8QA 2F7WA 4CT9A 4NWOA 4CTAA 5ERTA 2G2CA 2NQNA 2FTSA 5ERSA 4NWBA 2NQSA 1T3EA 1MKZA 2NQKA 1FC5A 2NRSA 1I6VD 4CTAB 1HQMD 5DMHA 3OI9A 4TK4A 1IHCA
chains in the Genus database with same CATH topology
1JLJA 4TK1A 3IWTA 3MCIA 4LHBA 2NQQA 3KBQA 4CT8A 5ERQA 3JSYA 1O8NA 2NQVA 4PD1A 4U91A 2NQRA 1O8OA 4UUXA 2PBQA 2X3LA 4UUWA 1DI6A 1G8RA 1DI7A 2QQ1A 2IS8A 5ERUA 2NQMA 1WU2A 5ERVA 1G8LA 4TWGA 5D8HB 2NRPA 1UZ5A 3MCHA 4PD0A 3MCJA 4UOCA 4XCWA 5D6GA 2NROA 3K6AA 2FU3A 1EAVA 1UUXA 3RFQA 5G2SA 2G4RA 2NQUA 4TK3A 5G2RA 1UUYA 4U90A 1IW7D 1Y5EA 3TCRA 5ERRA 1R2KA 2F7YA 3PZYA 1XI8A 1O8QA 2F7WA 4CT9A 4NWOA 4CTAA 5ERTA 2G2CA 2NQNA 2FTSA 5ERSA 4NWBA 2NQSA 1T3EA 1MKZA 2NQKA 1FC5A 2NRSA 1I6VD 4CTAB 1HQMD 3OI9A 4TK4A 1IHCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JLJ A;  4TK1 A;  3IWT A;  3MCI A;  4LHB A;  2NQQ A;  3KBQ A;  4CT8 A;  5ERQ A;  1O8N A;  2NQV A;  4PD1 A;  4U91 A;  2NQR A;  1O8O A;  4UUX A;  2PBQ A;  2X3L A;  4UUW A;  1DI6 A;  1G8R A;  1DI7 A;  2QQ1 A;  2IS8 A;  5ERU A;  2NQM A;  1WU2 A;  5ERV A;  1G8L A;  4TWG A;  2NRP A;  1UZ5 A;  3MCH A;  4PD0 A;  3MCJ A;  4UOC A;  4XCW A;  2NRO A;  3K6A A;  2FU3 A;  1EAV A;  1UUX A;  3RFQ A;  5G2S A;  2G4R A;  2NQU A;  4TK3 A;  5G2R A;  1UUY A;  4U90 A;  1Y5E A;  3TCR A;  5ERR A;  1R2K A;  2F7Y A;  3PZY A;  1XI8 A;  1O8Q A;  2F7W A;  4CT9 A;  4NWO A;  4CTA A;  5ERT A;  2G2C A;  2NQN A;  2FTS A;  5ERS A;  2NQS A;  1T3E A;  1MKZ A;  2NQK A;  1FC5 A;  2NRS A;  4CTA B;  3OI9 A;  4TK4 A;  1IHC A; 
#chains in the Genus database with same CATH topology
 1JLJ A;  4TK1 A;  3IWT A;  3MCI A;  3DQQ A;  4LHB A;  2NQQ A;  3KBQ A;  4CT8 A;  5ERQ A;  3JSY A;  1O8N A;  2NQV A;  4PD1 A;  4U91 A;  2NQR A;  1O8O A;  4UUX A;  2PBQ A;  2X3L A;  4UUW A;  1DI6 A;  1G8R A;  1DI7 A;  2QQ1 A;  2IS8 A;  5ERU A;  2NQM A;  1WU2 A;  5ERV A;  1G8L A;  4TWG A;  5D8H B;  2NRP A;  1UZ5 A;  3MCH A;  4PD0 A;  3MCJ A;  4UOC A;  4XCW A;  5D6G A;  2NRO A;  3K6A A;  2FU3 A;  1EAV A;  1UUX A;  3RFQ A;  5G2S A;  2G4R A;  2NQU A;  4TK3 A;  5G2R A;  1UUY A;  4U90 A;  1IW7 D;  1Y5E A;  1YZY A;  3TCR A;  5ERR A;  1R2K A;  2F7Y A;  3PZY A;  1XI8 A;  1O8Q A;  2F7W A;  4CT9 A;  4NWO A;  4CTA A;  5ERT A;  2G2C A;  2NQN A;  2FTS A;  5ERS A;  4NWB A;  2NQS A;  1T3E A;  1MKZ A;  2NQK A;  1FC5 A;  2NRS A;  1I6V D;  4CTA B;  1HQM D;  5DMH A;  3OI9 A;  4TK4 A;  1IHC A; 
#chains in the Genus database with same CATH homology
 1JLJ A;  4TK1 A;  3IWT A;  3MCI A;  4LHB A;  2NQQ A;  3KBQ A;  4CT8 A;  5ERQ A;  3JSY A;  1O8N A;  2NQV A;  4PD1 A;  4U91 A;  2NQR A;  1O8O A;  4UUX A;  2PBQ A;  2X3L A;  4UUW A;  1DI6 A;  1G8R A;  1DI7 A;  2QQ1 A;  2IS8 A;  5ERU A;  2NQM A;  1WU2 A;  5ERV A;  1G8L A;  4TWG A;  5D8H B;  2NRP A;  1UZ5 A;  3MCH A;  4PD0 A;  3MCJ A;  4UOC A;  4XCW A;  5D6G A;  2NRO A;  3K6A A;  2FU3 A;  1EAV A;  1UUX A;  3RFQ A;  5G2S A;  2G4R A;  2NQU A;  4TK3 A;  5G2R A;  1UUY A;  4U90 A;  1IW7 D;  1Y5E A;  3TCR A;  5ERR A;  1R2K A;  2F7Y A;  3PZY A;  1XI8 A;  1O8Q A;  2F7W A;  4CT9 A;  4NWO A;  4CTA A;  5ERT A;  2G2C A;  2NQN A;  2FTS A;  5ERS A;  4NWB A;  2NQS A;  1T3E A;  1MKZ A;  2NQK A;  1FC5 A;  2NRS A;  1I6V D;  4CTA B;  1HQM D;  3OI9 A;  4TK4 A;  1IHC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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