2NT7A

Crystal structure of ptp1b-inhibitor complex
Total Genus 103
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
103
sequence length
297
structure length
297
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLDMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Probing acid replacements of thiophene PTP1B inhibitors.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 1
total genus 103
structure length 297
sequence length 297
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2006-11-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 2nt7A00
2GJTA 2NTAA 3I36A 1YTNA 2HC2A 3GXGA 2PBNA 1YPTA 4WU2A 2A8BA 3O3LA 1G4WR 1PTYA 2H03A 2GP0A 3ZV2A 1XRIA 2H02A 2B4SA 4YR8B 2NT2A 2ESBA 3EAXA 4TVVA 1G1GA 4RH5A 4D3QA 2HNPA 5KADA 2HXPA 2BIJA 2H4KA 1WRMA 4D3RA 1I9TA 5KA4A 3EB1A 2PA5A 3V0GA 3PS5A 2OZ5A 2FJNA 5KACA 2CMBA 1FQ1A 4GE6A 2F6YA 1AAXA 4OHHA 5M43A 3BM8A 3OMHA 3F9BA 2CM7A 3QKQA 3S4EA 4Y14A 1G1FA 4ZN5A 2VEYA 2M3VA 2BGEA 5I6VA 2IMGA 1PXHA 4GWFA 4GE5A 3S3FA 5KA1A 3QCHA 5K23A 2I5XA 2QDPA 1C86A 2CNFA 2F71A 4NYHA 1I9SA 4HRFA 3S3EA 1I57A 2HY3A 1RPMA 3F99A 3QCKA 3D44A 4RI5A 2QBSA 2BV5A 2B4UA 2PI7A 4NNDA 1U24A 5K24A 1YZ4A 2E0TA 3RZ2A 5KA9A 1KAVA 1SUGA 4HJQA 5KA7A 2F6VA 4ZI4A 3ZMQA 3B7OA 1U25A 5EHRA 2Q05A 2NZ6A 1Q6PA 2R0BA 3OLRA 5HDEA 3H2XA 4Y2EA 1Q1MA 1Q6TA 4KYQA 2BZLA 3M4UA 2DXPA 1BZHA 3LJ8A 1RXDA 3SMEA 3MMJA 3EU0A 1T48A 3O4UA 2I4GA 5EHPA 1OHCA 2CM3A 4MBBA 4QBEA 4R0TA 3A5JA 1NL9A 4GFUA 1XXVA 3I7ZA 3ZMPA 2ZN7A 4QAPA 3BRHA 1OEUA 1PA9A 4OHIA 1PTVA 4QBWA 4JMJA 4KI9A 3D1HA 2I3UA 3QCFA 1OHEA 2F6ZA 3D9CA 3SR9A 1G1HA 1ZZWA 2I42A 4S0GA 1OETA 4GFVA 4WOHA 1YGRA 2GWOA 2HCMA 4R0SA 4I8NA 1G4US 4ICZA 2F6FA 4B04A 3EZZA 3O4TA 5BZXA 4DGPA 4J51A 2H4GA 1EEOA 2HVLA 1EENA 4H34A 3QCNA 2I6PA 1PA1A 2J17A 2HB1A 1ONYA 2VEUA 3QKPA 5KABA 3V0JA 1NWEA 2OOQA 3V0DA 2YDUA 3QCLA 3F9AA 2I75A 2CFVA 2VEXA 1G7GA 1R6HA 5BX1A 2I4HA 4YAAA 4IKCA 4WTYA 3QCIA 3V0HA 2F70A 2G59A 4RHGA 1Q6JA 5KA0A 4D3PA 2BGDA 3QCMA 2OC3A 2I6MA 1GWZA 1ECVA 1XBOA 4GE2A 2QBRA 2CM2A 2QBQA 3QCDA 1JF7A 1G7FA 1YFOA 3BLTA 2VEVA 1XM2A 2QBPA 2QCTA 1WAXA 2J16A 2PT0A 5KA2A 1NNYA 2Y2FA 1D5RA 1M3GA 5J8RA 1ONZA 2F6TA 2QEPA 4BJOA 3QCGA 4PYHA 5KA8A 2Q47A 4RKKA 1QZ0A 3F41A 2C46A 4NWGA 3V0FA 2WGPA 3ZM2A 1YTWA 3AWEA 1Q6SA 1C87A 3MOWA 2B07A 3I80A 2B4OA 4NWFA 5K22A 3O4SA 1C84A 3MOZA 1T49A 1C85A 4GRZA 4HJPA 3ZM3A 1YN9A 1L8KA 2CNIA 2I6IA 4H1OA 2JJDA 1NZ7A 2A3KA 2MBCA 2CMCA 4RH9A 5IBMA 1MKPA 1Q6NA 4R30A 4BPCA 1JLNA 4ERCA 2J16B 4NX8A 2AZRA 2F6WA 1XXPA 3O5XA 1KAKA 2I6JA 2FJMA 1FPRA 2CNEA 2SHPA 3AWGA 1VHRA 1ZC0A 2ZMMA 3QCBA 4WU3A 3U96A 4JBCA 1GFYA 2Y96A 1PYNA 1YWFA 1OESA 1A5YA 1YTSA 4Z6BA 5BZZA 1V3AA 2C7SA 1ZCKA 2G6ZA 5K9WA 1PH0A 3QCCA 5BUGA 2QDMA 1NO6A 5KA3A 2I3RA 1OEVA 2NT7A 2VEWA 3A5KA 1L8GA 1WCHA 1OEOX 3D42A 2B49A 2P6XA 3ZM1A 3GXHA 5KAAA 3RGQA 1YGUA 2RF6A 5MMZB 3QCJA 3N0AA 4GS0A 4RDDA 5IBSA 2B4PA 4QUMA 4KYRA 1PTTA 1T4JA 1P15A 2CMAA 2HNQA 2P4DA 4PVGA 3NMEA 4QUNA 4OHDA 2H4VA 1OHDA 1LQFA 4OHEA 2AHSA 3S3HA 3RO1A 2QDCA 1PTUA 1U26A 2PQ5A 5GTJA 3F81A 3EMUA 3S3KA 3S4OA 2PSZA 5AWXA 3ZM0A 3RGOA 1Q6MA 5K25A 2NV5A 3CM3A 4OHLA 1X24A 2QCJA 1C88A 4JMKA 1NWLA 3BLUA 4AZ1A 3QCEA 4JNBA 2B3OA 2CM8A 2OUDA 2H04A 3AWFA 2CNGA 2I4EA 1OEMX 2F46A 4ZRTA 3D1QA 3CWEA 4RI4A 2NLKA 1ZCLA 3V0IA 1BZJA 1LARA 2CJZA 4DGXA 1C83A 4GRYA 3V0EA 1BZCA 2CNHA 2HC1A 1J4XA 2FH7A 1FPZA 2I6OA 3D1OA 2I1YA 5LXQB 1QXKA 1LYVA 4QAHA 5K9VA
chains in the Genus database with same CATH superfamily
2GJTA 2NTAA 3I36A 1YTNA 2HC2A 3GXGA 2PBNA 1YPTA 4CVKA 4WU2A 2A8BA 3O3LA 1G4WR 1PTYA 2H03A 2GP0A 3ZV2A 1XRIA 2H02A 2B4SA 4YR8B 2NT2A 4C13A 2ESBA 3EAXA 1O5ZA 4HV4A 4TVVA 1G1GA 4RH5A 4D3QA 2XJAA 3PYZA 2HNPA 5KADA 2HXPA 2BIJA 2H4KA 1WRMA 4D3RA 1I9TA 5KA4A 3EB1A 2PA5A 3V0GA 2X5OA 3PS5A 2OZ5A 2FJNA 5KACA 2CMBA 1FQ1A 4GE6A 2F6YA 1AAXA 4OHHA 5M43A 3BM8A 3OMHA 3F9BA 2CM7A 3QKQA 3S4EA 4Y14A 1G1FA 4ZN5A 2VEYA 3MVNA 2M3VA 3N2AA 2BGEA 5I6VA 2IMGA 1PXHA 4GWFA 4GE5A 3S3FA 5KA1A 2JFFA 3QCHA 4QF5A 5K23A 1JBVA 2I5XA 2QDPA 1C86A 2CNFA 2F71A 4NYHA 1I9SA 4HRFA 3S3EA 1I57A 2HY3A 2Y67A 1RPMA 3F99A 3QCKA 3D44A 4RI5A 2QBSA 4ZIYA 2BV5A 2B4UA 2UUOA 2PI7A 4NNDA 1U24A 5K24A 1YZ4A 2E0TA 3RZ2A 5KA9A 1KAVA 1SUGA 4HJQA 5KA7A 2F6VA 4ZI4A 3ZMQA 3B7OA 1U25A 5EHRA 2Q05A 2NZ6A 1Q6PA 2R0BA 3OLRA 5HDEA 3H2XA 4Y2EA 1Q1MA 1Q6TA 4KYQA 2BZLA 3M4UA 2VORA 2DXPA 1P3DA 1BZHA 3LJ8A 1RXDA 3UAGA 2Y66A 3SMEA 4C12A 3MMJA 3EU0A 1T48A 3O4UA 2I4GA 5EHPA 1OHCA 2CM3A 4MBBA 4QBEA 4R0TA 3A5JA 1NL9A 4GFUA 1XXVA 3I7ZA 3ZMPA 2ZN7A 2JFHA 4QAPA 3BRHA 1OEUA 1PA9A 4OHIA 1PTVA 4QBWA 4JMJA 4KI9A 1J6UA 2Y68A 3D1HA 2I3UA 3QCFA 1OHEA 2F6ZA 3D9CA 3SR9A 1G1HA 2F00A 1ZZWA 2I42A 4S0GA 1OETA 4GFVA 4WOHA 1YGRA 1JBWA 2GWOA 2HCMA 4R0SA 3LK7A 4I8NA 1G4US 4ICZA 2F6FA 4B04A 2Y1OA 3EZZA 3O4TA 5BZXA 4DGPA 4J51A 2H4GA 1EEOA 5A5EA 3ZL8A 2HVLA 1EENA 4H34A 3QCNA 2I6PA 1PA1A 2J17A 2HB1A 1ONYA 4UAGA 2VEUA 3QKPA 5KABA 3HN7A 3V0JA 1NWEA 2OOQA 3V0DA 2YDUA 3QCLA 3F9AA 2I75A 2CFVA 2VEXA 1G7GA 1R6HA 5BX1A 2I4HA 4YAAA 2VOSA 4IKCA 4WTYA 3QCIA 3V0HA 2F70A 2G59A 4RHGA 1Q6JA 5KA0A 4QDIA 2UAGA 4QAHA 4D3PA 2BGDA 3QCMA 2OC3A 2I6MA 1GWZA 1ECVA 1XBOA 3ZM6A 4GE2A 2QBRA 2CM2A 2QBQA 3QCDA 2WTZA 2XPCA 1JF7A 1G7FA 1YFOA 3BLTA 2VEVA 1XM2A 2QBPA 2QCTA 1WAXA 2J16A 2PT0A 5KA2A 2UUPA 1NNYA 2Y2FA 1D5RA 1EEHA 1M3GA 5J8RA 2AM1A 1ONZA 2F6TA 1GQYA 2QEPA 4BJOA 3QCGA 4PYHA 5KA8A 2Q47A 4RKKA 1QZ0A 3F41A 2C46A 4NWGA 3V0FA 2WGPA 3ZM2A 1YTWA 3AWEA 1Q6SA 1C87A 3MOWA 2GCAA 2B07A 3I80A 2B4OA 4NWFA 5K22A 3O4SA 1C84A 3MOZA 2JFGA 1T49A 1C85A 4BUBA 1P31A 4GRZA 1W7KA 4HJPA 3ZM3A 1YN9A 1FGSA 1L8KA 2CNIA 2I6IA 4H1OA 2JJDA 2MBCA 1NZ7A 2A3KA 2GC5A 2CMCA 4RH9A 5IBMA 1MKPA 1Q6NA 1E0DA 4R30A 4BPCA 1JLNA 4ERCA 2J16B 4NX8A 2AZRA 2F6WA 1XXPA 1KAKA 2I6JA 3O5XA 2FJMA 1FPRA 2CNEA 2SHPA 3AWGA 1VHRA 1ZC0A 2ZMMA 4CVLA 3QCBA 4WU3A 3U96A 4JBCA 1GFYA 2Y96A 1PYNA 1YWFA 1OESA 1A5YA 1YTSA 4Z6BA 5BZZA 1V3AA 2C7SA 1ZCKA 2G6ZA 5K9WA 1PH0A 3QCCA 5BUGA 2QDMA 1NO6A 4CVMA 5KA3A 2I3RA 1OEVA 2NT7A 2VEWA 3A5KA 1L8GA 1WCHA 1OEOX 3D42A 2B49A 1GG4A 2P6XA 3ZM1A 3GXHA 5A5FA 5KAAA 1UAGA 3RGQA 1YGUA 2RF6A 5MMZB 3QCJA 3N0AA 1E8CA 4GS0A 4RDDA 2GC6A 5IBSA 2B4PA 4QUMA 4KYRA 1PTTA 1T4JA 1P15A 2CMAA 2HNQA 2P4DA 4PVGA 3ZM5A 3NMEA 4QUNA 4OHDA 1GQQA 2H4VA 1OHDA 1LQFA 4OHEA 2AHSA 3S3HA 3RO1A 2QDCA 1PTUA 1U26A 2PQ5A 5GTJA 3F81A 3EMUA 3S3KA 3S4OA 2PSZA 5AWXA 3ZM0A 3RGOA 1Q6MA 5K25A 2NV5A 3CM3A 4OHLA 1X24A 2QCJA 1C88A 4JMKA 1NWLA 3BLUA 4AZ1A 3QCEA 4JNBA 2B3OA 2CM8A 2OUDA 2H04A 3AWFA 2CNGA 2I4EA 1OEMX 2F46A 4ZRTA 3D1QA 3CWEA 4RI4A 2NLKA 1ZCLA 3V0IA 1BZJA 1LARA 1W78A 2CJZA 3NRSA 4DGXA 1C83A 2GCBA 4GRYA 2VTEA 3V0EA 1BZCA 2CNHA 2WJPA 4BUCA 2HC1A 1J4XA 2FH7A 1FPZA 2I6OA 3D1OA 2I1YA 2AM2A 5LXQB 1QXKA 1LYVA 2VTDA 3QCZA 5K9VA
chains in the Genus database with same CATH topology
2GJTA 2NTAA 3I36A 1YTNA 2HC2A 3GXGA 2PBNA 1YPTA 4WU2A 2A8BA 3O3LA 1G4WR 1PTYA 2H03A 2GP0A 3ZV2A 1XRIA 2H02A 2B4SA 4YR8B 2NT2A 2ESBA 3EAXA 4TVVA 1G1GA 4RH5A 4D3QA 2HNPA 5KADA 2HXPA 2BIJA 2H4KA 1WRMA 4D3RA 1I9TA 5KA4A 3EB1A 2PA5A 3V0GA 3PS5A 2OZ5A 2FJNA 5KACA 2CMBA 1FQ1A 4GE6A 2F6YA 1AAXA 4OHHA 5M43A 3BM8A 3OMHA 3F9BA 2CM7A 3QKQA 3S4EA 4Y14A 1G1FA 4ZN5A 2VEYA 2M3VA 2BGEA 5I6VA 2IMGA 1PXHA 4GWFA 4GE5A 3S3FA 5KA1A 3QCHA 5K23A 2I5XA 2QDPA 1C86A 2CNFA 2F71A 4NYHA 1I9SA 4HRFA 3S3EA 1I57A 2HY3A 1RPMA 3F99A 3QCKA 3D44A 4RI5A 2QBSA 2BV5A 2B4UA 2PI7A 4NNDA 1U24A 5K24A 1YZ4A 2E0TA 3RZ2A 5KA9A 1KAVA 1SUGA 4HJQA 5KA7A 2F6VA 4ZI4A 3ZMQA 3B7OA 1U25A 5EHRA 2Q05A 2NZ6A 1Q6PA 2R0BA 3OLRA 5HDEA 3H2XA 4Y2EA 1Q1MA 1Q6TA 4KYQA 2BZLA 3M4UA 2DXPA 1BZHA 3LJ8A 1RXDA 3SMEA 3MMJA 3EU0A 1T48A 3O4UA 2I4GA 5EHPA 1OHCA 2CM3A 4MBBA 4QBEA 4R0TA 3A5JA 1NL9A 4GFUA 1XXVA 3I7ZA 3ZMPA 2ZN7A 4QAPA 3BRHA 1OEUA 1PA9A 4OHIA 1PTVA 4QBWA 4JMJA 4KI9A 3D1HA 2I3UA 3QCFA 1OHEA 2F6ZA 3D9CA 3SR9A 1G1HA 1ZZWA 2I42A 4S0GA 1OETA 4GFVA 4WOHA 1YGRA 2GWOA 2HCMA 4R0SA 4I8NA 1G4US 4ICZA 2F6FA 4B04A 3EZZA 3O4TA 5BZXA 4DGPA 4J51A 2H4GA 1EEOA 2HVLA 1EENA 4H34A 3QCNA 2I6PA 1PA1A 2J17A 2HB1A 1ONYA 2VEUA 3QKPA 5KABA 3V0JA 1NWEA 2OOQA 3V0DA 2YDUA 3QCLA 3F9AA 2I75A 2CFVA 2VEXA 1G7GA 1R6HA 5BX1A 2I4HA 4YAAA 4IKCA 4WTYA 3QCIA 3V0HA 2F70A 2G59A 4RHGA 1Q6JA 5KA0A 4D3PA 2BGDA 3QCMA 2OC3A 2I6MA 1GWZA 1ECVA 1XBOA 4GE2A 2QBRA 2CM2A 2QBQA 3QCDA 1JF7A 1G7FA 1YFOA 3BLTA 2VEVA 1XM2A 2QBPA 2QCTA 1WAXA 2J16A 2PT0A 5KA2A 1NNYA 2Y2FA 1D5RA 1M3GA 5J8RA 1ONZA 2F6TA 2QEPA 4BJOA 3QCGA 4PYHA 5KA8A 2Q47A 4RKKA 1QZ0A 3F41A 2C46A 4NWGA 3V0FA 2WGPA 3ZM2A 1YTWA 3AWEA 1Q6SA 1C87A 3MOWA 2B07A 3I80A 2B4OA 4NWFA 5K22A 3O4SA 1C84A 3MOZA 1T49A 1C85A 4GRZA 4HJPA 3ZM3A 1YN9A 1L8KA 2CNIA 2I6IA 4H1OA 2JJDA 1NZ7A 2A3KA 2MBCA 2CMCA 4RH9A 5IBMA 1MKPA 1Q6NA 4R30A 4BPCA 1JLNA 4ERCA 2J16B 4NX8A 2AZRA 2F6WA 1XXPA 3O5XA 1KAKA 2I6JA 2FJMA 1FPRA 2CNEA 2SHPA 3AWGA 1VHRA 1ZC0A 2ZMMA 3QCBA 4WU3A 3U96A 4JBCA 1GFYA 2Y96A 1PYNA 1YWFA 1OESA 1A5YA 1YTSA 4Z6BA 5BZZA 1V3AA 2C7SA 1ZCKA 2G6ZA 5K9WA 1PH0A 3QCCA 5BUGA 2QDMA 1NO6A 5KA3A 2I3RA 1OEVA 2NT7A 2VEWA 3A5KA 1L8GA 1WCHA 1OEOX 3D42A 2B49A 2P6XA 3ZM1A 3GXHA 5KAAA 3RGQA 1YGUA 2RF6A 5MMZB 3QCJA 3N0AA 4GS0A 4RDDA 5IBSA 2B4PA 4QUMA 4KYRA 1PTTA 1T4JA 1P15A 2CMAA 2HNQA 2P4DA 4PVGA 3NMEA 4QUNA 4OHDA 2H4VA 1OHDA 1LQFA 4OHEA 2AHSA 3S3HA 3RO1A 2QDCA 1PTUA 1U26A 2PQ5A 5GTJA 3F81A 3EMUA 3S3KA 3S4OA 2PSZA 5AWXA 3ZM0A 3RGOA 1Q6MA 5K25A 2NV5A 3CM3A 4OHLA 1X24A 2QCJA 1C88A 4JMKA 1NWLA 3BLUA 4AZ1A 3QCEA 4JNBA 2B3OA 2CM8A 2OUDA 2H04A 3AWFA 2CNGA 2I4EA 1OEMX 2F46A 4ZRTA 3D1QA 3CWEA 4RI4A 2NLKA 1ZCLA 3V0IA 1BZJA 1LARA 2CJZA 4DGXA 1C83A 4GRYA 3V0EA 1BZCA 2CNHA 2HC1A 1J4XA 2FH7A 1FPZA 2I6OA 3D1OA 2I1YA 5LXQB 1QXKA 1LYVA 4QAHA 5K9VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GJT A;  2NTA A;  3I36 A;  1YTN A;  2HC2 A;  3GXG A;  2PBN A;  1YPT A;  4WU2 A;  2A8B A;  3O3L A;  1G4W R;  1PTY A;  2H03 A;  2GP0 A;  3ZV2 A;  1XRI A;  2H02 A;  2B4S A;  4YR8 B;  2NT2 A;  2ESB A;  3EAX A;  4TVV A;  1G1G A;  4RH5 A;  4D3Q A;  2HNP A;  5KAD A;  2HXP A;  2BIJ A;  2H4K A;  1WRM A;  4D3R A;  1I9T A;  5KA4 A;  3EB1 A;  2PA5 A;  3V0G A;  3PS5 A;  2OZ5 A;  2FJN A;  5KAC A;  2CMB A;  1FQ1 A;  4GE6 A;  2F6Y A;  1AAX A;  4OHH A;  5M43 A;  3BM8 A;  3OMH A;  3F9B A;  2CM7 A;  3QKQ A;  3S4E A;  4Y14 A;  1G1F A;  4ZN5 A;  2VEY A;  2M3V A;  2BGE A;  5I6V A;  2IMG A;  1PXH A;  4GWF A;  4GE5 A;  3S3F A;  5KA1 A;  3QCH A;  5K23 A;  2I5X A;  2QDP A;  1C86 A;  2CNF A;  2F71 A;  4NYH A;  1I9S A;  4HRF A;  3S3E A;  1I57 A;  2HY3 A;  1RPM A;  3F99 A;  3QCK A;  3D44 A;  4RI5 A;  2QBS A;  2BV5 A;  2B4U A;  2PI7 A;  4NND A;  1U24 A;  5K24 A;  1YZ4 A;  2E0T A;  3RZ2 A;  5KA9 A;  1KAV A;  1SUG A;  4HJQ A;  5KA7 A;  2F6V A;  4ZI4 A;  3ZMQ A;  3B7O A;  1U25 A;  5EHR A;  2Q05 A;  2NZ6 A;  1Q6P A;  2R0B A;  3OLR A;  5HDE A;  3H2X A;  4Y2E A;  1Q1M A;  1Q6T A;  4KYQ A;  2BZL A;  3M4U A;  2DXP A;  1BZH A;  3LJ8 A;  1RXD A;  3SME A;  3MMJ A;  3EU0 A;  1T48 A;  3O4U A;  2I4G A;  5EHP A;  1OHC A;  2CM3 A;  4MBB A;  4QBE A;  4R0T A;  3A5J A;  1NL9 A;  4GFU A;  1XXV A;  3I7Z A;  3ZMP A;  2ZN7 A;  4QAP A;  3BRH A;  1OEU A;  1PA9 A;  4OHI A;  1PTV A;  4QBW A;  4JMJ A;  4KI9 A;  3D1H A;  2I3U A;  3QCF A;  1OHE A;  2F6Z A;  3D9C A;  3SR9 A;  1G1H A;  1ZZW A;  2I42 A;  4S0G A;  1OET A;  4GFV A;  4WOH A;  1YGR A;  2GWO A;  2HCM A;  4R0S A;  4I8N A;  1G4U S;  4ICZ A;  2F6F A;  4B04 A;  3EZZ A;  3O4T A;  5BZX A;  4DGP A;  4J51 A;  2H4G A;  1EEO A;  2HVL A;  1EEN A;  4H34 A;  3QCN A;  2I6P A;  1PA1 A;  2J17 A;  2HB1 A;  1ONY A;  2VEU A;  3QKP A;  5KAB A;  3V0J A;  1NWE A;  2OOQ A;  3V0D A;  2YDU A;  3QCL A;  3F9A A;  2I75 A;  2CFV A;  2VEX A;  1G7G A;  1R6H A;  5BX1 A;  2I4H A;  4YAA A;  4IKC A;  4WTY A;  3QCI A;  3V0H A;  2F70 A;  2G59 A;  4RHG A;  1Q6J A;  5KA0 A;  4D3P A;  2BGD A;  3QCM A;  2OC3 A;  2I6M A;  1GWZ A;  1ECV A;  1XBO A;  4GE2 A;  2QBR A;  2CM2 A;  2QBQ A;  3QCD A;  1JF7 A;  1G7F A;  1YFO A;  3BLT A;  2VEV A;  1XM2 A;  2QBP A;  2QCT A;  1WAX A;  2J16 A;  2PT0 A;  5KA2 A;  1NNY A;  2Y2F A;  1D5R A;  1M3G A;  5J8R A;  1ONZ A;  2F6T A;  2QEP A;  4BJO A;  3QCG A;  4PYH A;  5KA8 A;  2Q47 A;  4RKK A;  1QZ0 A;  3F41 A;  2C46 A;  4NWG A;  3V0F A;  2WGP A;  3ZM2 A;  1YTW A;  3AWE A;  1Q6S A;  1C87 A;  3MOW A;  2B07 A;  3I80 A;  2B4O A;  4NWF A;  5K22 A;  3O4S A;  1C84 A;  3MOZ A;  1T49 A;  1C85 A;  4GRZ A;  4HJP A;  3ZM3 A;  1YN9 A;  1L8K A;  2CNI A;  2I6I A;  4H1O A;  2JJD A;  1NZ7 A;  2A3K A;  2MBC A;  2CMC A;  4RH9 A;  5IBM A;  1MKP A;  1Q6N A;  4R30 A;  4BPC A;  1JLN A;  4ERC A;  2J16 B;  4NX8 A;  2AZR A;  2F6W A;  1XXP A;  3O5X A;  1KAK A;  2I6J A;  2FJM A;  1FPR A;  2CNE A;  2SHP A;  3AWG A;  1VHR A;  1ZC0 A;  2ZMM A;  3QCB A;  4WU3 A;  3U96 A;  4JBC A;  1GFY A;  2Y96 A;  1PYN A;  1YWF A;  1OES A;  1A5Y A;  1YTS A;  4Z6B A;  5BZZ A;  1V3A A;  2C7S A;  1ZCK A;  2G6Z A;  5K9W A;  1PH0 A;  3QCC A;  5BUG A;  2QDM A;  1NO6 A;  5KA3 A;  2I3R A;  1OEV A;  2NT7 A;  2VEW A;  3A5K A;  1L8G A;  1WCH A;  1OEO X;  3D42 A;  2B49 A;  2P6X A;  3ZM1 A;  3GXH A;  5KAA A;  3RGQ A;  1YGU A;  2RF6 A;  5MMZ B;  3QCJ A;  3N0A A;  4GS0 A;  4RDD A;  5IBS A;  2B4P A;  4QUM A;  4KYR A;  1PTT A;  1T4J A;  1P15 A;  2CMA A;  2HNQ A;  2P4D A;  4PVG A;  3NME A;  4QUN A;  4OHD A;  2H4V A;  1OHD A;  1LQF A;  4OHE A;  2AHS A;  3S3H A;  3RO1 A;  2QDC A;  1PTU A;  1U26 A;  2PQ5 A;  5GTJ A;  3F81 A;  3EMU A;  3S3K A;  3S4O A;  2PSZ A;  5AWX A;  3ZM0 A;  3RGO A;  1Q6M A;  5K25 A;  2NV5 A;  3CM3 A;  4OHL A;  1X24 A;  2QCJ A;  1C88 A;  4JMK A;  1NWL A;  3BLU A;  4AZ1 A;  3QCE A;  4JNB A;  2B3O A;  2CM8 A;  2OUD A;  2H04 A;  3AWF A;  2CNG A;  2I4E A;  1OEM X;  2F46 A;  4ZRT A;  3D1Q A;  3CWE A;  4RI4 A;  2NLK A;  1ZCL A;  3V0I A;  1BZJ A;  1LAR A;  2CJZ A;  4DGX A;  1C83 A;  4GRY A;  3V0E A;  1BZC A;  2CNH A;  2HC1 A;  1J4X A;  2FH7 A;  1FPZ A;  2I6O A;  3D1O A;  2I1Y A;  5LXQ B;  1QXK A;  1LYV A;  4QAH A;  5K9V A; 
#chains in the Genus database with same CATH topology
 2GJT A;  2NTA A;  3I36 A;  1YTN A;  2HC2 A;  3GXG A;  2PBN A;  1YPT A;  4CVK A;  4WU2 A;  2A8B A;  3O3L A;  1G4W R;  1PTY A;  2H03 A;  2GP0 A;  3ZV2 A;  1XRI A;  2H02 A;  2B4S A;  4YR8 B;  2NT2 A;  4C13 A;  2ESB A;  3EAX A;  1O5Z A;  4HV4 A;  4TVV A;  1G1G A;  4RH5 A;  4D3Q A;  2XJA A;  3PYZ A;  2HNP A;  5KAD A;  2HXP A;  2BIJ A;  2H4K A;  1WRM A;  4D3R A;  1I9T A;  5KA4 A;  3EB1 A;  2PA5 A;  3V0G A;  2X5O A;  3PS5 A;  2OZ5 A;  2FJN A;  5KAC A;  2CMB A;  1FQ1 A;  4GE6 A;  2F6Y A;  1AAX A;  4OHH A;  5M43 A;  3BM8 A;  3OMH A;  3F9B A;  2CM7 A;  3QKQ A;  3S4E A;  4Y14 A;  1G1F A;  4ZN5 A;  2VEY A;  3MVN A;  2M3V A;  3N2A A;  2BGE A;  5I6V A;  2IMG A;  1PXH A;  4GWF A;  4GE5 A;  3S3F A;  5KA1 A;  2JFF A;  3QCH A;  4QF5 A;  5K23 A;  1JBV A;  2I5X A;  2QDP A;  1C86 A;  2CNF A;  2F71 A;  4NYH A;  1I9S A;  4HRF A;  3S3E A;  1I57 A;  2HY3 A;  2Y67 A;  1RPM A;  3F99 A;  3QCK A;  3D44 A;  4RI5 A;  2QBS A;  4ZIY A;  2BV5 A;  2B4U A;  2UUO A;  2PI7 A;  4NND A;  1U24 A;  5K24 A;  1YZ4 A;  2E0T A;  3RZ2 A;  5KA9 A;  1KAV A;  1SUG A;  4HJQ A;  5KA7 A;  2F6V A;  4ZI4 A;  3ZMQ A;  3B7O A;  1U25 A;  5EHR A;  2Q05 A;  2NZ6 A;  1Q6P A;  2R0B A;  3OLR A;  5HDE A;  3H2X A;  4Y2E A;  1Q1M A;  1Q6T A;  4KYQ A;  2BZL A;  3M4U A;  2VOR A;  2DXP A;  1P3D A;  1BZH A;  3LJ8 A;  1RXD A;  3UAG A;  2Y66 A;  3SME A;  4C12 A;  3MMJ A;  3EU0 A;  1T48 A;  3O4U A;  2I4G A;  5EHP A;  1OHC A;  2CM3 A;  4MBB A;  4QBE A;  4R0T A;  3A5J A;  1NL9 A;  4GFU A;  1XXV A;  3I7Z A;  3ZMP A;  2ZN7 A;  2JFH A;  4QAP A;  3BRH A;  1OEU A;  1PA9 A;  4OHI A;  1PTV A;  4QBW A;  4JMJ A;  4KI9 A;  1J6U A;  2Y68 A;  3D1H A;  2I3U A;  3QCF A;  1OHE A;  2F6Z A;  3D9C A;  3SR9 A;  1G1H A;  2F00 A;  1ZZW A;  2I42 A;  4S0G A;  1OET A;  4GFV A;  4WOH A;  1YGR A;  1JBW A;  2GWO A;  2HCM A;  4R0S A;  3LK7 A;  4I8N A;  1G4U S;  4ICZ A;  2F6F A;  4B04 A;  2Y1O A;  3EZZ A;  3O4T A;  5BZX A;  4DGP A;  4J51 A;  2H4G A;  1EEO A;  5A5E A;  3ZL8 A;  2HVL A;  1EEN A;  4H34 A;  3QCN A;  2I6P A;  1PA1 A;  2J17 A;  2HB1 A;  1ONY A;  4UAG A;  2VEU A;  3QKP A;  5KAB A;  3HN7 A;  3V0J A;  1NWE A;  2OOQ A;  3V0D A;  2YDU A;  3QCL A;  3F9A A;  2I75 A;  2CFV A;  2VEX A;  1G7G A;  1R6H A;  5BX1 A;  2I4H A;  4YAA A;  2VOS A;  4IKC A;  4WTY A;  3QCI A;  3V0H A;  2F70 A;  2G59 A;  4RHG A;  1Q6J A;  5KA0 A;  4QDI A;  2UAG A;  4QAH A;  4D3P A;  2BGD A;  3QCM A;  2OC3 A;  2I6M A;  1GWZ A;  1ECV A;  1XBO A;  3ZM6 A;  4GE2 A;  2QBR A;  2CM2 A;  2QBQ A;  3QCD A;  2WTZ A;  2XPC A;  1JF7 A;  1G7F A;  1YFO A;  3BLT A;  2VEV A;  1XM2 A;  2QBP A;  2QCT A;  1WAX A;  2J16 A;  2PT0 A;  5KA2 A;  2UUP A;  1NNY A;  2Y2F A;  1D5R A;  1EEH A;  1M3G A;  5J8R A;  2AM1 A;  1ONZ A;  2F6T A;  1GQY A;  2QEP A;  4BJO A;  3QCG A;  4PYH A;  5KA8 A;  2Q47 A;  4RKK A;  1QZ0 A;  3F41 A;  2C46 A;  4NWG A;  3V0F A;  2WGP A;  3ZM2 A;  1YTW A;  3AWE A;  1Q6S A;  1C87 A;  3MOW A;  2GCA A;  2B07 A;  3I80 A;  2B4O A;  4NWF A;  5K22 A;  3O4S A;  1C84 A;  3MOZ A;  2JFG A;  1T49 A;  1C85 A;  4BUB A;  1P31 A;  4GRZ A;  1W7K A;  4HJP A;  3ZM3 A;  1YN9 A;  1FGS A;  1L8K A;  2CNI A;  2I6I A;  4H1O A;  2JJD A;  2MBC A;  1NZ7 A;  2A3K A;  2GC5 A;  2CMC A;  4RH9 A;  5IBM A;  1MKP A;  1Q6N A;  1E0D A;  4R30 A;  4BPC A;  1JLN A;  4ERC A;  2J16 B;  4NX8 A;  2AZR A;  2F6W A;  1XXP A;  1KAK A;  2I6J A;  3O5X A;  2FJM A;  1FPR A;  2CNE A;  2SHP A;  3AWG A;  1VHR A;  1ZC0 A;  2ZMM A;  4CVL A;  3QCB A;  4WU3 A;  3U96 A;  4JBC A;  1GFY A;  2Y96 A;  1PYN A;  1YWF A;  1OES A;  1A5Y A;  1YTS A;  4Z6B A;  5BZZ A;  1V3A A;  2C7S A;  1ZCK A;  2G6Z A;  5K9W A;  1PH0 A;  3QCC A;  5BUG A;  2QDM A;  1NO6 A;  4CVM A;  5KA3 A;  2I3R A;  1OEV A;  2NT7 A;  2VEW A;  3A5K A;  1L8G A;  1WCH A;  1OEO X;  3D42 A;  2B49 A;  1GG4 A;  2P6X A;  3ZM1 A;  3GXH A;  5A5F A;  5KAA A;  1UAG A;  3RGQ A;  1YGU A;  2RF6 A;  5MMZ B;  3QCJ A;  3N0A A;  1E8C A;  4GS0 A;  4RDD A;  2GC6 A;  5IBS A;  2B4P A;  4QUM A;  4KYR A;  1PTT A;  1T4J A;  1P15 A;  2CMA A;  2HNQ A;  2P4D A;  4PVG A;  3ZM5 A;  3NME A;  4QUN A;  4OHD A;  1GQQ A;  2H4V A;  1OHD A;  1LQF A;  4OHE A;  2AHS A;  3S3H A;  3RO1 A;  2QDC A;  1PTU A;  1U26 A;  2PQ5 A;  5GTJ A;  3F81 A;  3EMU A;  3S3K A;  3S4O A;  2PSZ A;  5AWX A;  3ZM0 A;  3RGO A;  1Q6M A;  5K25 A;  2NV5 A;  3CM3 A;  4OHL A;  1X24 A;  2QCJ A;  1C88 A;  4JMK A;  1NWL A;  3BLU A;  4AZ1 A;  3QCE A;  4JNB A;  2B3O A;  2CM8 A;  2OUD A;  2H04 A;  3AWF A;  2CNG A;  2I4E A;  1OEM X;  2F46 A;  4ZRT A;  3D1Q A;  3CWE A;  4RI4 A;  2NLK A;  1ZCL A;  3V0I A;  1BZJ A;  1LAR A;  1W78 A;  2CJZ A;  3NRS A;  4DGX A;  1C83 A;  2GCB A;  4GRY A;  2VTE A;  3V0E A;  1BZC A;  2CNH A;  2WJP A;  4BUC A;  2HC1 A;  1J4X A;  2FH7 A;  1FPZ A;  2I6O A;  3D1O A;  2I1Y A;  2AM2 A;  5LXQ B;  1QXK A;  1LYV A;  2VTD A;  3QCZ A;  5K9V A; 
#chains in the Genus database with same CATH homology
 2GJT A;  2NTA A;  3I36 A;  1YTN A;  2HC2 A;  3GXG A;  2PBN A;  1YPT A;  4WU2 A;  2A8B A;  3O3L A;  1G4W R;  1PTY A;  2H03 A;  2GP0 A;  3ZV2 A;  1XRI A;  2H02 A;  2B4S A;  4YR8 B;  2NT2 A;  2ESB A;  3EAX A;  4TVV A;  1G1G A;  4RH5 A;  4D3Q A;  2HNP A;  5KAD A;  2HXP A;  2BIJ A;  2H4K A;  1WRM A;  4D3R A;  1I9T A;  5KA4 A;  3EB1 A;  2PA5 A;  3V0G A;  3PS5 A;  2OZ5 A;  2FJN A;  5KAC A;  2CMB A;  1FQ1 A;  4GE6 A;  2F6Y A;  1AAX A;  4OHH A;  5M43 A;  3BM8 A;  3OMH A;  3F9B A;  2CM7 A;  3QKQ A;  3S4E A;  4Y14 A;  1G1F A;  4ZN5 A;  2VEY A;  2M3V A;  2BGE A;  5I6V A;  2IMG A;  1PXH A;  4GWF A;  4GE5 A;  3S3F A;  5KA1 A;  3QCH A;  5K23 A;  2I5X A;  2QDP A;  1C86 A;  2CNF A;  2F71 A;  4NYH A;  1I9S A;  4HRF A;  3S3E A;  1I57 A;  2HY3 A;  1RPM A;  3F99 A;  3QCK A;  3D44 A;  4RI5 A;  2QBS A;  2BV5 A;  2B4U A;  2PI7 A;  4NND A;  1U24 A;  5K24 A;  1YZ4 A;  2E0T A;  3RZ2 A;  5KA9 A;  1KAV A;  1SUG A;  4HJQ A;  5KA7 A;  2F6V A;  4ZI4 A;  3ZMQ A;  3B7O A;  1U25 A;  5EHR A;  2Q05 A;  2NZ6 A;  1Q6P A;  2R0B A;  3OLR A;  5HDE A;  3H2X A;  4Y2E A;  1Q1M A;  1Q6T A;  4KYQ A;  2BZL A;  3M4U A;  2DXP A;  1BZH A;  3LJ8 A;  1RXD A;  3SME A;  3MMJ A;  3EU0 A;  1T48 A;  3O4U A;  2I4G A;  5EHP A;  1OHC A;  2CM3 A;  4MBB A;  4QBE A;  4R0T A;  3A5J A;  1NL9 A;  4GFU A;  1XXV A;  3I7Z A;  3ZMP A;  2ZN7 A;  4QAP A;  3BRH A;  1OEU A;  1PA9 A;  4OHI A;  1PTV A;  4QBW A;  4JMJ A;  4KI9 A;  3D1H A;  2I3U A;  3QCF A;  1OHE A;  2F6Z A;  3D9C A;  3SR9 A;  1G1H A;  1ZZW A;  2I42 A;  4S0G A;  1OET A;  4GFV A;  4WOH A;  1YGR A;  2GWO A;  2HCM A;  4R0S A;  4I8N A;  1G4U S;  4ICZ A;  2F6F A;  4B04 A;  3EZZ A;  3O4T A;  5BZX A;  4DGP A;  4J51 A;  2H4G A;  1EEO A;  2HVL A;  1EEN A;  4H34 A;  3QCN A;  2I6P A;  1PA1 A;  2J17 A;  2HB1 A;  1ONY A;  2VEU A;  3QKP A;  5KAB A;  3V0J A;  1NWE A;  2OOQ A;  3V0D A;  2YDU A;  3QCL A;  3F9A A;  2I75 A;  2CFV A;  2VEX A;  1G7G A;  1R6H A;  5BX1 A;  2I4H A;  4YAA A;  4IKC A;  4WTY A;  3QCI A;  3V0H A;  2F70 A;  2G59 A;  4RHG A;  1Q6J A;  5KA0 A;  4D3P A;  2BGD A;  3QCM A;  2OC3 A;  2I6M A;  1GWZ A;  1ECV A;  1XBO A;  4GE2 A;  2QBR A;  2CM2 A;  2QBQ A;  3QCD A;  1JF7 A;  1G7F A;  1YFO A;  3BLT A;  2VEV A;  1XM2 A;  2QBP A;  2QCT A;  1WAX A;  2J16 A;  2PT0 A;  5KA2 A;  1NNY A;  2Y2F A;  1D5R A;  1M3G A;  5J8R A;  1ONZ A;  2F6T A;  2QEP A;  4BJO A;  3QCG A;  4PYH A;  5KA8 A;  2Q47 A;  4RKK A;  1QZ0 A;  3F41 A;  2C46 A;  4NWG A;  3V0F A;  2WGP A;  3ZM2 A;  1YTW A;  3AWE A;  1Q6S A;  1C87 A;  3MOW A;  2B07 A;  3I80 A;  2B4O A;  4NWF A;  5K22 A;  3O4S A;  1C84 A;  3MOZ A;  1T49 A;  1C85 A;  4GRZ A;  4HJP A;  3ZM3 A;  1YN9 A;  1L8K A;  2CNI A;  2I6I A;  4H1O A;  2JJD A;  1NZ7 A;  2A3K A;  2MBC A;  2CMC A;  4RH9 A;  5IBM A;  1MKP A;  1Q6N A;  4R30 A;  4BPC A;  1JLN A;  4ERC A;  2J16 B;  4NX8 A;  2AZR A;  2F6W A;  1XXP A;  3O5X A;  1KAK A;  2I6J A;  2FJM A;  1FPR A;  2CNE A;  2SHP A;  3AWG A;  1VHR A;  1ZC0 A;  2ZMM A;  3QCB A;  4WU3 A;  3U96 A;  4JBC A;  1GFY A;  2Y96 A;  1PYN A;  1YWF A;  1OES A;  1A5Y A;  1YTS A;  4Z6B A;  5BZZ A;  1V3A A;  2C7S A;  1ZCK A;  2G6Z A;  5K9W A;  1PH0 A;  3QCC A;  5BUG A;  2QDM A;  1NO6 A;  5KA3 A;  2I3R A;  1OEV A;  2NT7 A;  2VEW A;  3A5K A;  1L8G A;  1WCH A;  1OEO X;  3D42 A;  2B49 A;  2P6X A;  3ZM1 A;  3GXH A;  5KAA A;  3RGQ A;  1YGU A;  2RF6 A;  5MMZ B;  3QCJ A;  3N0A A;  4GS0 A;  4RDD A;  5IBS A;  2B4P A;  4QUM A;  4KYR A;  1PTT A;  1T4J A;  1P15 A;  2CMA A;  2HNQ A;  2P4D A;  4PVG A;  3NME A;  4QUN A;  4OHD A;  2H4V A;  1OHD A;  1LQF A;  4OHE A;  2AHS A;  3S3H A;  3RO1 A;  2QDC A;  1PTU A;  1U26 A;  2PQ5 A;  5GTJ A;  3F81 A;  3EMU A;  3S3K A;  3S4O A;  2PSZ A;  5AWX A;  3ZM0 A;  3RGO A;  1Q6M A;  5K25 A;  2NV5 A;  3CM3 A;  4OHL A;  1X24 A;  2QCJ A;  1C88 A;  4JMK A;  1NWL A;  3BLU A;  4AZ1 A;  3QCE A;  4JNB A;  2B3O A;  2CM8 A;  2OUD A;  2H04 A;  3AWF A;  2CNG A;  2I4E A;  1OEM X;  2F46 A;  4ZRT A;  3D1Q A;  3CWE A;  4RI4 A;  2NLK A;  1ZCL A;  3V0I A;  1BZJ A;  1LAR A;  2CJZ A;  4DGX A;  1C83 A;  4GRY A;  3V0E A;  1BZC A;  2CNH A;  2HC1 A;  1J4X A;  2FH7 A;  1FPZ A;  2I6O A;  3D1O A;  2I1Y A;  5LXQ B;  1QXK A;  1LYV A;  4QAH A;  5K9V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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