2NU2I

Accommodation of positively-charged residues in a hydrophobic specificity pocket: crystal structures of sgpb in complex with omtky3 variants lys18i and arg18i
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
51
structure length
51
Chain Sequence
VDCSEYPKPACTREYRPLCGSDNKTYGNKCNFCNAVVESNGTLTLSHFGKC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I
rcsb
molecule keywords Streptogrisin B, Protease B
molecule tags Hydrolase
source organism Meleagris gallopavo
total genus 14
structure length 51
sequence length 51
ec nomenclature
pdb deposition date 2006-11-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00050 Kazal_1 Kazal-type serine protease inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.60.30 Alpha Beta 2-Layer Sandwich Wheat Germ Agglutinin (Isolectin 2); domain 1 Wheat Germ Agglutinin (Isolectin 2); domain 1 2nu2I00
1SGPI 1SGRI 2NU0I 2JZMA 1NUBA 5DAEA 2NU2I 2NU4I 1CHOI 3SEKC 2XRCA 1M8CA 4GI3C 2JXDA 1YU6C 2QQCA 2SGFI 2BUSA 2JYYA 1OMTA 1TIHA 2KMOA 1HPTA 4HGUA 5JHWC 1DS3I 2M5XA 4SGBI 1CT4I 2WCYA 1LR7A 1CGJI 2KMQA 1UVGA 1OYVI 1UVFA 2ERWA 1TBRR 2GKTI 2B0UC 1FYBA 3OVOA 3SGQI 2KCXA 1OMUA 2NU3I 1TBQR 1SGDI 2SGDI 2SGQI 2SGEI 1SGNI 1TURA 2ARPF 1TUSA 2KMRA 1HJAI 2N71A 1LR9A 2SGPI 1M8BA 2LEOA 1SGYI 1CT0I 1H0ZA 2KMPA 1SGQI 1N13A 1CT2I 1CGII 2GKRI 2N52A 4OVOA 1IY5A 1LR8A 1AN1I 1BUSA 1MT1A 2V53A 2GKVA 1PCEA 1SGEI 1IW4A 1BMOA 3HH2C 2OVOA 1R0RI 2QQDA 3SGBI 1PJUA 2N17A 1DS2I 1OVOA 1UUCA 3QTLD 1TGSI 1HDLA 1Z7KB 1YTPA 1KMAA 2NU1I 2F3CI 1Y1CA 2P6AC 3B4VC 3TJQA 1PPFI 1Y1BA 1IY6A 1CE3A 1CSOI
chains in the Genus database with same CATH superfamily
1SGPI 1SGRI 2NU0I 2JZMA 2ROWA 3OXGA 1X4SA 1K7TA 3D00A 2OD1A 2A20A 1NUBA 2L8EA 2NU2I 2NU4I 2RIJA 2LB7A 1CHOI 5DAEA 3SEKC 1ULKA 1V1IA 2X52A 2DKVA 2YQPA 3QAHA 2XRCA 1M8CA 3TO6A 3UFFA 5HQ8A 2JW6A 4GI3C 2JXDA 1YU6C 2QQEA 4FKDA 2QQCA 2UVOA 5FUWA 2W0TA 2SGFI 2BUSA 2JYYA 1OMTA 1P9ZA 1TIHA 1W3SA 2KMOA 5CCLA 1HPTA 4HGUA 2V1CA 2GVIA 2LUYA 2OZUA 5E3QA 5JHWC 1HEVA 1DS3I 3R5BA 5EX0A 1WGCA 2M5XA 4SGBI 4UXIA 1R79A 1CT4I 1UHAA 1X74A 2WCYA 1LR7A 2FNFX 2YUUA 3OL0A 1CGJI 2KMQA 1UVGA 3TOAA 4E1PA 1OYVI 1UVFA 1MJBA 3KY9A 4AMLA 3GOXA 2K9HA 1V1HA 3VDUA 2DB6A 2ERWA 1WKXA 3R5AA 4L9MA 1TBRR 3R5DA 5E3RA 1RFHA 5FUXA 2GKTI 1FAQA 2B0UC 1TOTA 1KBFA 3FSXA 2JA1A 2ODDA 1FYBA 2ENNA 3CXLA 3OVOA 4UXHA 3SGQI 2KCXA 5CCMA 1OMUA 1VDDA 2NU3I 2CWFA 5FUYA 4MPIA 1TBQR 2Y0MA 1SGDI 2SGDI 2SGQI 3UOEA 3VE5A 2J9RA 2ORWA 3FC3A 1Z2IA 2SGEI 1SGNI 1TURA 3TOBA 3UEJA 2ORVA 2OU2A 1FY7A 5J8CA 2ARPF 2WGCA 3QWPA 5HI7A 1TUSA 4E1RA 2ELIA 2GIVA 4A24A 2KMRA 1HJAI 2N71A 2UZ3A 3OXFA 2CJSC 1WGTA 2RC4A 1TBNA 3UGLA 1LR9A 1MJ9A 2SGPI 3UEYA 9WGAA 1M8BA 2LEOA 1MJAA 1SGYI 3E2IA 1CT0I 1S20A 3R5CA 1H0ZA 2KMPA 1SGQI 2PQ8A 1N13A 1XX6A 1XA6A 3TO7A 2B8TA 2QPOA 1TBOA 4JCVE 1CT2I 7WGAA 1CGII 2GKRI 2N52A 2J87A 2QQ0A 4OVOA 5J8FA 1IY5A 1LR8A 2E73A 2CWHA 4UXJA 1AN1I 1W4RA 1WTJA 2X3TA 3OXLA 1U5KA 1BUSA 3UGIA 3PDNA 5E3PA 1MT1A 2V53A 2GKVA 1PCEA 1SGEI 3FSYA 1PTRA 1IW4A 5EX3A 1BMOA 3HH2C 1Y8FA 3UGDA 4B6DA 2OVOA 1R0RI 2V1CC 2ENZA 1XBTA 1KBEA 2QQDA 3SGBI 1PJUA 1K7VA 2N17A 2N1AB 1DS2I 1OVOA 1UUCA 2E5RA 1TGSI 3QTLD 5FUVA 1K7UA 1HDLA 1Z7KB 2WVJA 3E59A 1YTPA 2L7XA 1ULMA 1FARA 3RU0A 1KMAA 2NU1I 2F3CI 1Y1CA 1PTQA 2P6AC 2VRWB 1NXUA 3B4VC 3TJQA 1ULNA 3MEKA 1PPFI 4WP4A 1Y1BA 3VDPA 2CWGA 4DNCA 1P9GA 3BJIA 1IY6A 3TO9A 1CE3A 1CSOI 1Q9BA 2DIPA
chains in the Genus database with same CATH topology
1SGPI 1SGRI 2NU0I 2JZMA 2ROWA 3OXGA 1X4SA 3D00A 2OD1A 2A20A 1NUBA 2L8EA 2NU2I 2NU4I 5DAEA 1CHOI 3SEKC 1V1IA 2YQPA 2XRCA 1M8CA 5HQ8A 3UFFA 2JW6A 4GI3C 2JXDA 1YU6C 2QQEA 4FKDA 2QQCA 5FUWA 2W0TA 2SGFI 2BUSA 2JYYA 1OMTA 1TIHA 1W3SA 2KMOA 5CCLA 1HPTA 4HGUA 2V1CA 2GVIA 2LUYA 5JHWC 1DS3I 5EX0A 2M5XA 4SGBI 4UXIA 1R79A 1CT4I 1X74A 2WCYA 3OL0A 1LR7A 2FNFX 2YUUA 1CGJI 2KMQA 1UVGA 4E1PA 1OYVI 1UVFA 3KY9A 3GOXA 2K9HA 1V1HA 3VDUA 2DB6A 2ERWA 4L9MA 1TBRR 1RFHA 5FUXA 2GKTI 1FAQA 2B0UC 1TOTA 1KBFA 2JA1A 2ODDA 1FYBA 2ENNA 3CXLA 3OVOA 4UXHA 3SGQI 2KCXA 5CCMA 1OMUA 1VDDA 2NU3I 5FUYA 1TBQR 3VE5A 1SGDI 2SGDI 2SGQI 2J9RA 2ORWA 3FC3A 2SGEI 1SGNI 1TURA 3UEJA 2ORVA 2ARPF 3QWPA 5HI7A 4E1RA 1TUSA 2ELIA 4A24A 2KMRA 1HJAI 2N71A 2UZ3A 3OXFA 2CJSC 1TBNA 3UGLA 1LR9A 2SGPI 3UEYA 1M8BA 2LEOA 1SGYI 3E2IA 1CT0I 1H0ZA 2KMPA 1SGQI 1N13A 1XX6A 1XA6A 2B8TA 2QPOA 1TBOA 4JCVE 1CT2I 1CGII 2GKRI 2N52A 2J87A 2QQ0A 4OVOA 1IY5A 1LR8A 2E73A 4UXJA 1AN1I 1W4RA 1BUSA 3OXLA 1U5KA 3UGIA 3PDNA 1MT1A 2V53A 2GKVA 1PCEA 1SGEI 1PTRA 1IW4A 5EX3A 1BMOA 3HH2C 1Y8FA 3UGDA 4B6DA 2OVOA 1R0RI 2V1CC 2ENZA 1XBTA 1KBEA 2QQDA 3SGBI 1PJUA 2N17A 2N1AB 1DS2I 1OVOA 1UUCA 2E5RA 1TGSI 3QTLD 5FUVA 1HDLA 1Z7KB 2WVJA 3E59A 1YTPA 2L7XA 3RU0A 1FARA 1KMAA 2NU1I 2F3CI 1Y1CA 1PTQA 2P6AC 2VRWB 3B4VC 3TJQA 3MEKA 1PPFI 1Y1BA 3VDPA 1IY6A 3BJIA 1CE3A 1CSOI 2DIPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SGP I;  1SGR I;  2NU0 I;  2JZM A;  1NUB A;  5DAE A;  2NU2 I;  2NU4 I;  1CHO I;  3SEK C;  2XRC A;  1M8C A;  4GI3 C;  2JXD A;  1YU6 C;  2QQC A;  2SGF I;  2BUS A;  2JYY A;  1OMT A;  1TIH A;  2KMO A;  1HPT A;  4HGU A;  5JHW C;  1DS3 I;  2M5X A;  4SGB I;  1CT4 I;  2WCY A;  1LR7 A;  1CGJ I;  2KMQ A;  1UVG A;  1OYV I;  1UVF A;  2ERW A;  1TBR R;  2GKT I;  2B0U C;  1FYB A;  3OVO A;  3SGQ I;  2KCX A;  1OMU A;  2NU3 I;  1TBQ R;  1SGD I;  2SGD I;  2SGQ I;  2SGE I;  1SGN I;  1TUR A;  2ARP F;  1TUS A;  2KMR A;  1HJA I;  2N71 A;  1LR9 A;  2SGP I;  1M8B A;  2LEO A;  1SGY I;  1CT0 I;  1H0Z A;  2KMP A;  1SGQ I;  1N13 A;  1CT2 I;  1CGI I;  2GKR I;  2N52 A;  4OVO A;  1IY5 A;  1LR8 A;  1AN1 I;  1BUS A;  1MT1 A;  2V53 A;  2GKV A;  1PCE A;  1SGE I;  1IW4 A;  1BMO A;  3HH2 C;  2OVO A;  1R0R I;  2QQD A;  3SGB I;  1PJU A;  2N17 A;  1DS2 I;  1OVO A;  1UUC A;  3QTL D;  1TGS I;  1HDL A;  1Z7K B;  1YTP A;  1KMA A;  2NU1 I;  2F3C I;  1Y1C A;  2P6A C;  3B4V C;  3TJQ A;  1PPF I;  1Y1B A;  1IY6 A;  1CE3 A;  1CSO I; 
#chains in the Genus database with same CATH topology
 1SGP I;  1SGR I;  2NU0 I;  2JZM A;  2ROW A;  3OXG A;  1X4S A;  1K7T A;  3D00 A;  2OD1 A;  2A20 A;  1NUB A;  2L8E A;  2NU2 I;  2NU4 I;  2RIJ A;  2LB7 A;  1CHO I;  5DAE A;  3SEK C;  1ULK A;  1V1I A;  2X52 A;  2DKV A;  2YQP A;  3QAH A;  2XRC A;  1M8C A;  3TO6 A;  3UFF A;  5HQ8 A;  2JW6 A;  4GI3 C;  2JXD A;  1YU6 C;  2QQE A;  4FKD A;  2QQC A;  2UVO A;  5FUW A;  2W0T A;  2SGF I;  2BUS A;  2JYY A;  1OMT A;  1P9Z A;  1TIH A;  1W3S A;  2KMO A;  5CCL A;  1HPT A;  4HGU A;  2V1C A;  2GVI A;  2LUY A;  2OZU A;  5E3Q A;  5JHW C;  1HEV A;  1DS3 I;  3R5B A;  5EX0 A;  1WGC A;  2M5X A;  4SGB I;  4UXI A;  1R79 A;  1CT4 I;  1UHA A;  1X74 A;  2WCY A;  1LR7 A;  2FNF X;  2YUU A;  3OL0 A;  1CGJ I;  2KMQ A;  1UVG A;  3TOA A;  4E1P A;  1OYV I;  1UVF A;  1MJB A;  3KY9 A;  4AML A;  3GOX A;  2K9H A;  1V1H A;  3VDU A;  2DB6 A;  2ERW A;  1WKX A;  3R5A A;  4L9M A;  1TBR R;  3R5D A;  5E3R A;  1RFH A;  5FUX A;  2GKT I;  1FAQ A;  2B0U C;  1TOT A;  1KBF A;  3FSX A;  2JA1 A;  2ODD A;  1FYB A;  2ENN A;  3CXL A;  3OVO A;  4UXH A;  3SGQ I;  2KCX A;  5CCM A;  1OMU A;  1VDD A;  2NU3 I;  2CWF A;  5FUY A;  4MPI A;  1TBQ R;  2Y0M A;  1SGD I;  2SGD I;  2SGQ I;  3UOE A;  3VE5 A;  2J9R A;  2ORW A;  3FC3 A;  1Z2I A;  2SGE I;  1SGN I;  1TUR A;  3TOB A;  3UEJ A;  2ORV A;  2OU2 A;  1FY7 A;  5J8C A;  2ARP F;  2WGC A;  3QWP A;  5HI7 A;  1TUS A;  4E1R A;  2ELI A;  2GIV A;  4A24 A;  2KMR A;  1HJA I;  2N71 A;  2UZ3 A;  3OXF A;  2CJS C;  1WGT A;  2RC4 A;  1TBN A;  3UGL A;  1LR9 A;  1MJ9 A;  2SGP I;  3UEY A;  9WGA A;  1M8B A;  2LEO A;  1MJA A;  1SGY I;  3E2I A;  1CT0 I;  1S20 A;  3R5C A;  1H0Z A;  2KMP A;  1SGQ I;  2PQ8 A;  1N13 A;  1XX6 A;  1XA6 A;  3TO7 A;  2B8T A;  2QPO A;  1TBO A;  4JCV E;  1CT2 I;  7WGA A;  1CGI I;  2GKR I;  2N52 A;  2J87 A;  2QQ0 A;  4OVO A;  5J8F A;  1IY5 A;  1LR8 A;  2E73 A;  2CWH A;  4UXJ A;  1AN1 I;  1W4R A;  1WTJ A;  2X3T A;  3OXL A;  1U5K A;  1BUS A;  3UGI A;  3PDN A;  5E3P A;  1MT1 A;  2V53 A;  2GKV A;  1PCE A;  1SGE I;  3FSY A;  1PTR A;  1IW4 A;  5EX3 A;  1BMO A;  3HH2 C;  1Y8F A;  3UGD A;  4B6D A;  2OVO A;  1R0R I;  2V1C C;  2ENZ A;  1XBT A;  1KBE A;  2QQD A;  3SGB I;  1PJU A;  1K7V A;  2N17 A;  2N1A B;  1DS2 I;  1OVO A;  1UUC A;  2E5R A;  1TGS I;  3QTL D;  5FUV A;  1K7U A;  1HDL A;  1Z7K B;  2WVJ A;  3E59 A;  1YTP A;  2L7X A;  1ULM A;  1FAR A;  3RU0 A;  1KMA A;  2NU1 I;  2F3C I;  1Y1C A;  1PTQ A;  2P6A C;  2VRW B;  1NXU A;  3B4V C;  3TJQ A;  1ULN A;  3MEK A;  1PPF I;  4WP4 A;  1Y1B A;  3VDP A;  2CWG A;  4DNC A;  1P9G A;  3BJI A;  1IY6 A;  3TO9 A;  1CE3 A;  1CSO I;  1Q9B A;  2DIP A; 
#chains in the Genus database with same CATH homology
 1SGP I;  1SGR I;  2NU0 I;  2JZM A;  2ROW A;  3OXG A;  1X4S A;  3D00 A;  2OD1 A;  2A20 A;  1NUB A;  2L8E A;  2NU2 I;  2NU4 I;  5DAE A;  1CHO I;  3SEK C;  1V1I A;  2YQP A;  2XRC A;  1M8C A;  5HQ8 A;  3UFF A;  2JW6 A;  4GI3 C;  2JXD A;  1YU6 C;  2QQE A;  4FKD A;  2QQC A;  5FUW A;  2W0T A;  2SGF I;  2BUS A;  2JYY A;  1OMT A;  1TIH A;  1W3S A;  2KMO A;  5CCL A;  1HPT A;  4HGU A;  2V1C A;  2GVI A;  2LUY A;  5JHW C;  1DS3 I;  5EX0 A;  2M5X A;  4SGB I;  4UXI A;  1R79 A;  1CT4 I;  1X74 A;  2WCY A;  3OL0 A;  1LR7 A;  2FNF X;  2YUU A;  1CGJ I;  2KMQ A;  1UVG A;  4E1P A;  1OYV I;  1UVF A;  3KY9 A;  3GOX A;  2K9H A;  1V1H A;  3VDU A;  2DB6 A;  2ERW A;  4L9M A;  1TBR R;  1RFH A;  5FUX A;  2GKT I;  1FAQ A;  2B0U C;  1TOT A;  1KBF A;  2JA1 A;  2ODD A;  1FYB A;  2ENN A;  3CXL A;  3OVO A;  4UXH A;  3SGQ I;  2KCX A;  5CCM A;  1OMU A;  1VDD A;  2NU3 I;  5FUY A;  1TBQ R;  3VE5 A;  1SGD I;  2SGD I;  2SGQ I;  2J9R A;  2ORW A;  3FC3 A;  2SGE I;  1SGN I;  1TUR A;  3UEJ A;  2ORV A;  2ARP F;  3QWP A;  5HI7 A;  4E1R A;  1TUS A;  2ELI A;  4A24 A;  2KMR A;  1HJA I;  2N71 A;  2UZ3 A;  3OXF A;  2CJS C;  1TBN A;  3UGL A;  1LR9 A;  2SGP I;  3UEY A;  1M8B A;  2LEO A;  1SGY I;  3E2I A;  1CT0 I;  1H0Z A;  2KMP A;  1SGQ I;  1N13 A;  1XX6 A;  1XA6 A;  2B8T A;  2QPO A;  1TBO A;  4JCV E;  1CT2 I;  1CGI I;  2GKR I;  2N52 A;  2J87 A;  2QQ0 A;  4OVO A;  1IY5 A;  1LR8 A;  2E73 A;  4UXJ A;  1AN1 I;  1W4R A;  1BUS A;  3OXL A;  1U5K A;  3UGI A;  3PDN A;  1MT1 A;  2V53 A;  2GKV A;  1PCE A;  1SGE I;  1PTR A;  1IW4 A;  5EX3 A;  1BMO A;  3HH2 C;  1Y8F A;  3UGD A;  4B6D A;  2OVO A;  1R0R I;  2V1C C;  2ENZ A;  1XBT A;  1KBE A;  2QQD A;  3SGB I;  1PJU A;  2N17 A;  2N1A B;  1DS2 I;  1OVO A;  1UUC A;  2E5R A;  1TGS I;  3QTL D;  5FUV A;  1HDL A;  1Z7K B;  2WVJ A;  3E59 A;  1YTP A;  2L7X A;  3RU0 A;  1FAR A;  1KMA A;  2NU1 I;  2F3C I;  1Y1C A;  1PTQ A;  2P6A C;  2VRW B;  3B4V C;  3TJQ A;  3MEK A;  1PPF I;  1Y1B A;  3VDP A;  1IY6 A;  3BJI A;  1CE3 A;  1CSO I;  2DIP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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