2NVXC

Rna polymerase ii elongation complex in 5 mm mg+2 with 2'-dutp
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
266
structure length
266
Chain Sequence
EEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIVSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYDPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVDQVVVRGIDTLQKKVASILLALTQMDQD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3'
publication title Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
pubmed doi rcsb
molecule tags Transcription,transferase/dna-rna hybrid
total genus 46
structure length 266
sequence length 266
ec nomenclature
pdb deposition date 2006-11-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF01000 RNA_pol_A_bac RNA polymerase Rpb3/RpoA insert domain
C PF01193 RNA_pol_L RNA polymerase Rpb3/Rpb11 dimerisation domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.120.12 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 DNA-directed RNA polymerase, insert domain 2nvxC02
3.30.1360.10 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 RNA polymerase, RBP11-like subunit 2nvxC01
4C3HK 3GTQK 3S1MC 4C2MK 3HKZD 3I4NK 5IYDK 5M5YK 2PA8D 1TWCK 1XPPA 4A3BC 3H0GC 3GTOK 3S16K 4YFKA 5IYCC 4A3JK 5TMCA 2E2JK 2B63K 3HOVC 2JA8K 4C3HC 1TWHC 4XLPA 3GTQC 3I4NC 4A3CC 2NVQK 4X6AK 3RZOK 1K83K 4C3IK 3M3YK 1TWCC 3H3VL 3HOXC 3S1QK 1I6VA 3S16C 2JA5K 2R93C 2R92K 4KN7A 2JA7K 4A3JC 2B63C 4A93C 5IYBK 4A3IK 2JA6K 5C44C 2E2HC 1SFOK 2Y0SD 4A3EC 4Q5SA 5M3MK 3GTGK 3HOWK 4X6AC 4XSZA 4OIOA 1K83C 3RZOC 5M5WK 3S2DK 2A6EA 1TWFK 1I50K 2WAQL 2NVXC 2CW0A 2JA7C 3S17C 4AYBL 2JA6C 3CQZC 4KN4A 5TMFA 4QJVA 4BBSC 5FLMK 3HOZK 3I4MK 4G7HA 5C4XC 3K7AK 5IP7K 2Y0SL 3DXJA 3S2HK 2A69A 4XSXA 4YFXA 4OIRA 3S1NC 3FKIK 4BXXC 3EQLA 5C4JC 3PO2C 4G7OA 3S14C 4QJVB 2R7ZK 4Y52K 4KMUA 4A3KC 4OINA 3FKIC 3S1RK 2YU9K 1HQMA 2NVTK 4C2MC 5IYDC 4OIQA 2WAQD 5FLMC 1Y1WK 3M4OK 4AYBD 5FJ8K 3GTOC 3HOUK 4YG2A 1ZYRA 4XLNA 2WB1L 1WCMK 3S2HC 3GTPK 4BBRK 2E2JC 4Y52C 2R7ZC 2JA8C 1R9TK 2NVTC 3GTMK 4ZH4A 2NVQC 1Y1WC 3S1QC 4MEYA 4C3IC 3M3YC 3M4OC 1Y1VK 2NVYK 4Y7NK 3HOUC 4LJZA 2JA5C 1WCMC 2R92C 4A3MK 4BBRC 4Q4ZA 5IYBC 4LK1A 4A3IC 1I3QK 2O5JA 4C3JK 4A3LK 3HOWC 1R9TC 1SFOC 2WB1D 3GTMC 3GTGC 2PPBA 5M3FK 2VUMK 3GTLK 3GTKK 4BY1K 3HOYK 4QIWD 4Y7NC 3S15K 4A3DK 1Y1VC 3S2DC 2O5IA 1TWGK 2E2IK 1TWFC 1I50C 4LLGA 4A3MC 3PO3K 5C3EK 4C3JC 4OIPA 5IP9K 4A3LC 3I4MC 3HOZC 2VUMC 3GTJK 4MEXA 3K7AC 4BY1C 3GTKC 3HOYC 3S15C 5IP7C 3S1MK 2E2IC 3H0GK 4JK1A 3WODA 4QIWL 3PO3C 4GZYA 5C3EC 1I6HK 3S1RC 5IP9C 2YU9C 3GTJC 5D4DA 4NOIA 1TWHK 4A3GK 4MQ9A 1TWAK 3GTPC 3HOXK 2A6HA 4YFNA 2R93K 3RZDK 5M5XK 3HOVK 1I6HC 4A93K 4LK0A 5C44K 2E2HK 2NVYC 4A3EK 4BY7K 4A3FK 4A3GC 1TWAC 2PMZD 3HKZL 2NVXK 1I3QC 3RZDC 2PA8L 3S17K 1IW7A 3GTLC 1YNNA 4A3CK 2BE5A 3CQZK 1YNJA 4A3DC 4BY7C 4BBSK 4A3FC 1TWGC 4G7ZA 5C4XK 4A3BK 1SMYA 5IYCK 3S1NK 4BXXK 5C4JK 3PO2K 1BDFA 3S14K 2A68A 4A3KK 2PMZL 3H3VD
chains in the Genus database with same CATH superfamily
4C3HK 4C2MK 3GTKA 3T01A 5HL8A 5M5YK 1TWCK 1XPPA 4A3BC 5EGHA 3GTOK 3FOEA 5IYCC 5TMCA 2E2JK 4XCHA 2B63K 4KMAA 4C3HC 3AQPA 1IE0A 1TWCC 3HOXC 2JA5K 2ZFZA 2B63C 5IYBK 1V5VA 2JA6K 2E2HC 3HOWK 1SFOK 2Y0SD 5M3MK 3GTGK 2L5NA 4GTFA 4OIOA 3S2DK 3AD7C 4AYBL 3OEPA 2JA6C 4KC6A 2E2HA 4KN4A 4BBSC 3HOZK 3I4MK 4KDDA 3A8JA 3K7AK 4GTDA 1X31C 5IP7K 2A69A 4XSXA 4YFXA 1ISEA 3S1NC 4WJ4A 3PO2C 4U67S 1DCOA 2RH6A 2XCOA 2R7ZK 4KMUA 2NVTK 3FKIC 1O2BA 2KPUA 2WAQD 5JVHS 4P5AA 4YG2A 2P8TA 4KARA 1VRQC 4BBRK 2R7ZC 2JA8C 1XZPB 2NVTC 3GTMK 3FKIA 1PJ7A 3S1QC 4C3IC 3T00A 4GTAA 1EI6A 2R92C 4BBRC 4Q4ZA 1RU0A 4C3JK 3GTMC 2WB1D 3GTLK 1TWGK 4WF9S 2E2IK 2R92A 3FOFA 2V6SA 3AD8C 1JVIA 4C3JC 4OIPA 4J3NA 5JVOA 4WILA 4WFAS 3QX3A 2E2IC 2ZJRS 1VLOA 1TWHK 1WSVA 1TWAK 3GTPC 4G0UA 5TJ3A 4BKWA 1EK8A 4A93K 4AH6A 5C44K 5IOSA 4BY7K 1Y1WA 4RMFA 1TWAC 3GTPA 2PMZD 1I3QC 2CFAB 3LAPA 1EH1A 1WOSA 3CQZK 1YNJA 4WFNS 4BY7C 1XXBA 5C4XK 2GAGC 5C4JK 1I3QA 1BJTA 2VUMA 3S1MC 3BP3A 5IYDK 2PA8D 3H0GC 2ZUFA 1ZXOA 2GSNA 2V6UA 1XZQA 4FM9A 4XLPA 5JFEA 4GTCA 1O25A 1K83K 4GT9A 3RZOK 1I6VA 3H0GA 1G51A 4KN7A 2JA7K 1B4AA 1IS1A 1C0AA 3RZOC 1K83C 5M5WK 2A6EA 1O28A 5DM7S 2NVXC 2JA7C 3S17C 4O2DA 5TMFA 3HXAA 3OPFA 1K83A 3S2HK 1F9NA 4BXXC 1ZVUA 2NVXA 3A8KA 4A3KC 4OINA 2YU9K 4C2MC 4OIQA 3L4JA 3M4OK 2ZJPS 3GTOC 3HOUK 1PJ6A 5EGEA 1WCMK 3S2HC 3CAGA 1EFWA 3GEEA 2E2JC 1R9TK 2GAHC 1JOEA 1O2FB 4ZH4A 2NVYK 4MEYA 1XXAA 3M4OC 1TWCA 3HOUC 3GTOA 2JA5C 1WCMC 3GEHA 4BLAA 3BUEA 5IYBC 4KMHA 3TFIA 2B63A 2O5JA 3HOWC 1R9TC 1SFOC 3GTGC 1FEUA 2XCQA 4KM9A 4A3DK 1WOPA 1J98A 4KM8A 1BS2A 1IBAA 3S2DC 5HQHA 2O5IA 4BLBA 3Q3QA 4P5BA 2JA5A 4LLGA 4C45A 4KAWX 4IO9S 5IP9K 2JA6A 1J6VA 1SFOA 3GTGA 3I4MC 3HOZC 3S0XA 1WSRA 3K7AC 5IP7C 4JK1A 1KQ4A 1B4BA 1VGXA 1I6HK 5IP9C 3H3VD 2A6HA 4IOCS 2R93K 2R7ZA 3TTGA 1I6HC 2L3UA 1USMA 1F7UA 4A3EK 4PAAA 5CJ9A 1F7VA 3GTMA 3GTLC 2ZUEA 3GDZA 1HI9A 4LR2A 1TWGC 1BGWA 3S14K 3BP8C 4KATA 3GTLA 1YCLA 3ERED 3GTQK 3HKZD 1TWGA 1GE9A 2E2IA 4GTEA 1L0WA 5JVGS 3L4KA 1TWHC 3GTQC 2NVQK 4X6AK 3M3YK 1DCHA 1XZQB 2FQOA 2GSOA 3LPXA 2P5MA 4A93C 4A3IK 1USOA 5C44C 4KB4A 3CF5S 1TWHA 3GTQA 4X6AC 4XSZA 3FHZA 1TWAA 4DDQA 1TWFK 1I50K 2WAQL 2CW0A 4M1XA 3CQZC 3AH5A 4GTBA 4QJVA 3IPJA 5C4XC 5CHPA 3DXJA 1EQRA 3EQLA 5C4JC 4G7OA 4Y52K 2JH3A 3S1RK 1HQMA 5IYDC 3CQZA 5E68A 1O2AA 4AYBD 1ZYRA 2ZJQS 2WB1L 4Y52C 5IOQA 4Y7NK 1F93A 1IQ0A 3DLLS 4LJZA 3GSIA 2KWAA 4LK1A 4GFQA 4KMDA 2PPBA 5M3FK 3GTKK 4BY1K 3HOYK 4Y7NC 2CFAA 1DCPA 3V4GA 3G4CA 3N0BA 3PO3K 2JA7A 1IL2A 1VJEA 2EBBA 3A8IA 3GTJK 4MEXA 4BY1C 3GTKC 3HOYC 1O29A 5DM6S 3WODA 4QIWL 3PO3C 4GZYA 2V6TA 5L46A 2YU9C 1DD5A 1PJ5A 3GTJC 3HOXK 4YFNA 1ZQ1C 2FQTA 2KXYA 4LK0A 2YU9A 2E2HK 2NVYC 3TFJA 3VA7A 4WJ3M 3GTJA 4P9SA 1WCMA 2PA8L 1IW7A 1R9TA 1YNNA 4A3DC 1WQFA 2NVYA 4BBSK 1XXCA 3T02A 4KB2A 1O27A 1SMYA 3S1NK 3PO2K 1BDFA 4PABA 1O26A 3G4AA 3HOVK 3FKIK 3I4NK 1O24A 3S16K 1WORA 4YFKA 4WFBS 4A3JK 3HOVC 2JA8K 3AQOA 3I4NC 3S1QK 4C3IK 1AB4A 4LOWA 2XCRB 3H3VL 3S16C 2R93C 2R92K 4A3JC 4G0WA 3AD9C 4A3EC 4G0VA 4Q5SA 1WQGA 3ADAC 2R93A 2D6FC 2RGRA 5FLMK 4G7HA 2Y0SL 3GEIA 5IORA 4OIRA 4QJVB 3LAJA 3S14C 4ILDA 1Y1WK 5FLMC 1WIHA 3JSTA 4FZBA 5FJ8K 1UV7A 1XZPA 4XLNA 1J6WA 3GTPK 4KASA 1INNA 2KQ1A 1JQWA 2W7VA 2NVQC 1Y1WC 3M3YC 1Y1VK 4A3MK 4A3IC 1I3QK 1VH2A 1YX2A 3SZYA 3N3YA 4A3LK 3PIPS 2VUMK 4QIWD 1ZBSA 3S15K 1Y1VC 1TWFC 1I50C 4A3MC 5C3EK 4A3LC 2GSUA 3MMLB 4GTLA 2VUMC 3PIOS 3S1MK 1WQHA 3S15C 4LQYA 1Y1VA 3H0GK 1J6XA 1TWFA 1I50A 2PHCB 5C3EC 3S1RC 3TFHA 5D4DA 4NOIA 4IOAS 2Y3PA 4A3GK 4MQ9A 3SZZA 4WCES 3RZDK 5M5XK 1WOOA 4A3FK 4A3GC 3LYWA 3HKZL 3NUHA 2NVXK 3RZDC 3S17K 5HL7S 4A3CK 2BE5A 4A3FC 4G7ZA 4A3BK 3N0CA 5IYCK 4BXXK 5IOTA 3OREA 2A68A 4A3KK 2PMZL 4A3CC 3GIRA
chains in the Genus database with same CATH topology
4C3HK 3GTQK 3S1MC 4C2MK 3HKZD 3I4NK 5IYDK 5M5YK 2PA8D 1TWCK 1XPPA 4A3BC 3H0GC 3GTOK 3S16K 4YFKA 5IYCC 4A3JK 5TMCA 2E2JK 2B63K 3HOVC 2JA8K 4C3HC 1TWHC 4XLPA 3GTQC 3I4NC 4A3CC 2NVQK 4X6AK 3RZOK 1K83K 4C3IK 3M3YK 1TWCC 3H3VL 3HOXC 3S1QK 1I6VA 3S16C 2JA5K 2R93C 2R92K 4KN7A 2JA7K 4A3JC 2B63C 4A93C 5IYBK 4A3IK 2JA6K 5C44C 2E2HC 1SFOK 2Y0SD 4A3EC 4Q5SA 5M3MK 3GTGK 3HOWK 4X6AC 4XSZA 4OIOA 1K83C 3RZOC 5M5WK 3S2DK 2A6EA 1TWFK 1I50K 2WAQL 2NVXC 2CW0A 2JA7C 3S17C 4AYBL 2JA6C 3CQZC 4KN4A 5TMFA 4QJVA 4BBSC 5FLMK 3HOZK 3I4MK 4G7HA 5C4XC 3K7AK 5IP7K 2Y0SL 3DXJA 3S2HK 2A69A 4XSXA 4YFXA 4OIRA 3S1NC 3FKIK 4BXXC 3EQLA 5C4JC 3PO2C 4G7OA 3S14C 4QJVB 2R7ZK 4Y52K 4KMUA 4A3KC 4OINA 3FKIC 3S1RK 2YU9K 1HQMA 2NVTK 4C2MC 5IYDC 4OIQA 2WAQD 5FLMC 1Y1WK 3M4OK 4AYBD 5FJ8K 3GTOC 3HOUK 4YG2A 1ZYRA 4XLNA 2WB1L 1WCMK 3S2HC 3GTPK 4BBRK 2E2JC 4Y52C 2R7ZC 2JA8C 1R9TK 2NVTC 3GTMK 4ZH4A 2NVQC 1Y1WC 3S1QC 4MEYA 4C3IC 3M3YC 3M4OC 1Y1VK 2NVYK 4Y7NK 3HOUC 4LJZA 2JA5C 1WCMC 2R92C 4A3MK 4BBRC 4Q4ZA 5IYBC 4LK1A 4A3IC 1I3QK 2O5JA 4C3JK 4A3LK 3HOWC 1R9TC 1SFOC 2WB1D 3GTMC 3GTGC 2PPBA 5M3FK 2VUMK 3GTLK 3GTKK 4BY1K 3HOYK 4QIWD 4Y7NC 3S15K 4A3DK 1Y1VC 3S2DC 2O5IA 1TWGK 2E2IK 1TWFC 1I50C 4LLGA 4A3MC 3PO3K 5C3EK 4C3JC 4OIPA 5IP9K 4A3LC 3I4MC 3HOZC 2VUMC 3GTJK 4MEXA 3K7AC 4BY1C 3GTKC 3HOYC 3S15C 5IP7C 3S1MK 2E2IC 3H0GK 4JK1A 3WODA 4QIWL 3PO3C 4GZYA 5C3EC 1I6HK 3S1RC 5IP9C 2YU9C 3GTJC 5D4DA 4NOIA 1TWHK 4A3GK 4MQ9A 1TWAK 3GTPC 3HOXK 2A6HA 4YFNA 2R93K 3RZDK 5M5XK 3HOVK 1I6HC 4A93K 4LK0A 5C44K 2E2HK 2NVYC 4A3EK 4BY7K 4A3FK 4A3GC 1TWAC 2PMZD 3HKZL 2NVXK 1I3QC 3RZDC 2PA8L 3S17K 1IW7A 3GTLC 1YNNA 4A3CK 2BE5A 3CQZK 1YNJA 4A3DC 4BY7C 4BBSK 4A3FC 1TWGC 4G7ZA 5C4XK 4A3BK 1SMYA 5IYCK 3S1NK 4BXXK 5C4JK 3PO2K 1BDFA 3S14K 2A68A 4A3KK 2PMZL 3H3VD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4C3H K;  3GTQ K;  3S1M C;  4C2M K;  3HKZ D;  3I4N K;  5IYD K;  5M5Y K;  2PA8 D;  1TWC K;  1XPP A;  4A3B C;  3H0G C;  3GTO K;  3S16 K;  4YFK A;  5IYC C;  4A3J K;  5TMC A;  2E2J K;  2B63 K;  3HOV C;  2JA8 K;  4C3H C;  1TWH C;  4XLP A;  3GTQ C;  3I4N C;  4A3C C;  2NVQ K;  4X6A K;  3RZO K;  1K83 K;  4C3I K;  3M3Y K;  1TWC C;  3H3V L;  3HOX C;  3S1Q K;  1I6V A;  3S16 C;  2JA5 K;  2R93 C;  2R92 K;  4KN7 A;  2JA7 K;  4A3J C;  2B63 C;  4A93 C;  5IYB K;  4A3I K;  2JA6 K;  5C44 C;  2E2H C;  1SFO K;  2Y0S D;  4A3E C;  4Q5S A;  5M3M K;  3GTG K;  3HOW K;  4X6A C;  4XSZ A;  4OIO A;  1K83 C;  3RZO C;  5M5W K;  3S2D K;  2A6E A;  1TWF K;  1I50 K;  2WAQ L;  2NVX C;  2CW0 A;  2JA7 C;  3S17 C;  4AYB L;  2JA6 C;  3CQZ C;  4KN4 A;  5TMF A;  4QJV A;  4BBS C;  5FLM K;  3HOZ K;  3I4M K;  4G7H A;  5C4X C;  3K7A K;  5IP7 K;  2Y0S L;  3DXJ A;  3S2H K;  2A69 A;  4XSX A;  4YFX A;  4OIR A;  3S1N C;  3FKI K;  4BXX C;  3EQL A;  5C4J C;  3PO2 C;  4G7O A;  3S14 C;  4QJV B;  2R7Z K;  4Y52 K;  4KMU A;  4A3K C;  4OIN A;  3FKI C;  3S1R K;  2YU9 K;  1HQM A;  2NVT K;  4C2M C;  5IYD C;  4OIQ A;  2WAQ D;  5FLM C;  1Y1W K;  3M4O K;  4AYB D;  5FJ8 K;  3GTO C;  3HOU K;  4YG2 A;  1ZYR A;  4XLN A;  2WB1 L;  1WCM K;  3S2H C;  3GTP K;  4BBR K;  2E2J C;  4Y52 C;  2R7Z C;  2JA8 C;  1R9T K;  2NVT C;  3GTM K;  4ZH4 A;  2NVQ C;  1Y1W C;  3S1Q C;  4MEY A;  4C3I C;  3M3Y C;  3M4O C;  1Y1V K;  2NVY K;  4Y7N K;  3HOU C;  4LJZ A;  2JA5 C;  1WCM C;  2R92 C;  4A3M K;  4BBR C;  4Q4Z A;  5IYB C;  4LK1 A;  4A3I C;  1I3Q K;  2O5J A;  4C3J K;  4A3L K;  3HOW C;  1R9T C;  1SFO C;  2WB1 D;  3GTM C;  3GTG C;  2PPB A;  5M3F K;  2VUM K;  3GTL K;  3GTK K;  4BY1 K;  3HOY K;  4QIW D;  4Y7N C;  3S15 K;  4A3D K;  1Y1V C;  3S2D C;  2O5I A;  1TWG K;  2E2I K;  1TWF C;  1I50 C;  4LLG A;  4A3M C;  3PO3 K;  5C3E K;  4C3J C;  4OIP A;  5IP9 K;  4A3L C;  3I4M C;  3HOZ C;  2VUM C;  3GTJ K;  4MEX A;  3K7A C;  4BY1 C;  3GTK C;  3HOY C;  3S15 C;  5IP7 C;  3S1M K;  2E2I C;  3H0G K;  4JK1 A;  3WOD A;  4QIW L;  3PO3 C;  4GZY A;  5C3E C;  1I6H K;  3S1R C;  5IP9 C;  2YU9 C;  3GTJ C;  5D4D A;  4NOI A;  1TWH K;  4A3G K;  4MQ9 A;  1TWA K;  3GTP C;  3HOX K;  2A6H A;  4YFN A;  2R93 K;  3RZD K;  5M5X K;  3HOV K;  1I6H C;  4A93 K;  4LK0 A;  5C44 K;  2E2H K;  2NVY C;  4A3E K;  4BY7 K;  4A3F K;  4A3G C;  1TWA C;  2PMZ D;  3HKZ L;  2NVX K;  1I3Q C;  3RZD C;  2PA8 L;  3S17 K;  1IW7 A;  3GTL C;  1YNN A;  4A3C K;  2BE5 A;  3CQZ K;  1YNJ A;  4A3D C;  4BY7 C;  4BBS K;  4A3F C;  1TWG C;  4G7Z A;  5C4X K;  4A3B K;  1SMY A;  5IYC K;  3S1N K;  4BXX K;  5C4J K;  3PO2 K;  1BDF A;  3S14 K;  2A68 A;  4A3K K;  2PMZ L;  3H3V D; 
#chains in the Genus database with same CATH topology
 4C3H K;  4C2M K;  3GTK A;  3T01 A;  5HL8 A;  5M5Y K;  1TWC K;  1XPP A;  4A3B C;  5EGH A;  3GTO K;  3FOE A;  5IYC C;  5TMC A;  2E2J K;  4XCH A;  2B63 K;  4KMA A;  4C3H C;  3AQP A;  1IE0 A;  1TWC C;  3HOX C;  2JA5 K;  2ZFZ A;  2B63 C;  5IYB K;  1V5V A;  2JA6 K;  2E2H C;  3HOW K;  1SFO K;  2Y0S D;  5M3M K;  3GTG K;  2L5N A;  4GTF A;  4OIO A;  3S2D K;  3AD7 C;  4AYB L;  3OEP A;  2JA6 C;  4KC6 A;  2E2H A;  4KN4 A;  4BBS C;  3HOZ K;  3I4M K;  4KDD A;  3A8J A;  3K7A K;  4GTD A;  1X31 C;  5IP7 K;  2A69 A;  4XSX A;  4YFX A;  1ISE A;  3S1N C;  4WJ4 A;  3PO2 C;  4U67 S;  1DCO A;  2RH6 A;  2XCO A;  2R7Z K;  4KMU A;  2NVT K;  3FKI C;  1O2B A;  2KPU A;  2WAQ D;  5JVH S;  4P5A A;  4YG2 A;  2P8T A;  4KAR A;  1VRQ C;  4BBR K;  2R7Z C;  2JA8 C;  1XZP B;  2NVT C;  3GTM K;  3FKI A;  1PJ7 A;  3S1Q C;  4C3I C;  3T00 A;  4GTA A;  1EI6 A;  2R92 C;  4BBR C;  4Q4Z A;  1RU0 A;  4C3J K;  3GTM C;  2WB1 D;  3GTL K;  1TWG K;  4WF9 S;  2E2I K;  2R92 A;  3FOF A;  2V6S A;  3AD8 C;  1JVI A;  4C3J C;  4OIP A;  4J3N A;  5JVO A;  4WIL A;  4WFA S;  3QX3 A;  2E2I C;  2ZJR S;  1VLO A;  1TWH K;  1WSV A;  1TWA K;  3GTP C;  4G0U A;  5TJ3 A;  4BKW A;  1EK8 A;  4A93 K;  4AH6 A;  5C44 K;  5IOS A;  4BY7 K;  1Y1W A;  4RMF A;  1TWA C;  3GTP A;  2PMZ D;  1I3Q C;  2CFA B;  3LAP A;  1EH1 A;  1WOS A;  3CQZ K;  1YNJ A;  4WFN S;  4BY7 C;  1XXB A;  5C4X K;  2GAG C;  5C4J K;  1I3Q A;  1BJT A;  2VUM A;  3S1M C;  3BP3 A;  5IYD K;  2PA8 D;  3H0G C;  2ZUF A;  1ZXO A;  2GSN A;  2V6U A;  1XZQ A;  4FM9 A;  4XLP A;  5JFE A;  4GTC A;  1O25 A;  1K83 K;  4GT9 A;  3RZO K;  1I6V A;  3H0G A;  1G51 A;  4KN7 A;  2JA7 K;  1B4A A;  1IS1 A;  1C0A A;  3RZO C;  1K83 C;  5M5W K;  2A6E A;  1O28 A;  5DM7 S;  2NVX C;  2JA7 C;  3S17 C;  4O2D A;  5TMF A;  3HXA A;  3OPF A;  1K83 A;  3S2H K;  1F9N A;  4BXX C;  1ZVU A;  2NVX A;  3A8K A;  4A3K C;  4OIN A;  2YU9 K;  4C2M C;  4OIQ A;  3L4J A;  3M4O K;  2ZJP S;  3GTO C;  3HOU K;  1PJ6 A;  5EGE A;  1WCM K;  3S2H C;  3CAG A;  1EFW A;  3GEE A;  2E2J C;  1R9T K;  2GAH C;  1JOE A;  1O2F B;  4ZH4 A;  2NVY K;  4MEY A;  1XXA A;  3M4O C;  1TWC A;  3HOU C;  3GTO A;  2JA5 C;  1WCM C;  3GEH A;  4BLA A;  3BUE A;  5IYB C;  4KMH A;  3TFI A;  2B63 A;  2O5J A;  3HOW C;  1R9T C;  1SFO C;  3GTG C;  1FEU A;  2XCQ A;  4KM9 A;  4A3D K;  1WOP A;  1J98 A;  4KM8 A;  1BS2 A;  1IBA A;  3S2D C;  5HQH A;  2O5I A;  4BLB A;  3Q3Q A;  4P5B A;  2JA5 A;  4LLG A;  4C45 A;  4KAW X;  4IO9 S;  5IP9 K;  2JA6 A;  1J6V A;  1SFO A;  3GTG A;  3I4M C;  3HOZ C;  3S0X A;  1WSR A;  3K7A C;  5IP7 C;  4JK1 A;  1KQ4 A;  1B4B A;  1VGX A;  1I6H K;  5IP9 C;  3H3V D;  2A6H A;  4IOC S;  2R93 K;  2R7Z A;  3TTG A;  1I6H C;  2L3U A;  1USM A;  1F7U A;  4A3E K;  4PAA A;  5CJ9 A;  1F7V A;  3GTM A;  3GTL C;  2ZUE A;  3GDZ A;  1HI9 A;  4LR2 A;  1TWG C;  1BGW A;  3S14 K;  3BP8 C;  4KAT A;  3GTL A;  1YCL A;  3ERE D;  3GTQ K;  3HKZ D;  1TWG A;  1GE9 A;  2E2I A;  4GTE A;  1L0W A;  5JVG S;  3L4K A;  1TWH C;  3GTQ C;  2NVQ K;  4X6A K;  3M3Y K;  1DCH A;  1XZQ B;  2FQO A;  2GSO A;  3LPX A;  2P5M A;  4A93 C;  4A3I K;  1USO A;  5C44 C;  4KB4 A;  3CF5 S;  1TWH A;  3GTQ A;  4X6A C;  4XSZ A;  3FHZ A;  1TWA A;  4DDQ A;  1TWF K;  1I50 K;  2WAQ L;  2CW0 A;  4M1X A;  3CQZ C;  3AH5 A;  4GTB A;  4QJV A;  3IPJ A;  5C4X C;  5CHP A;  3DXJ A;  1EQR A;  3EQL A;  5C4J C;  4G7O A;  4Y52 K;  2JH3 A;  3S1R K;  1HQM A;  5IYD C;  3CQZ A;  5E68 A;  1O2A A;  4AYB D;  1ZYR A;  2ZJQ S;  2WB1 L;  4Y52 C;  5IOQ A;  4Y7N K;  1F93 A;  1IQ0 A;  3DLL S;  4LJZ A;  3GSI A;  2KWA A;  4LK1 A;  4GFQ A;  4KMD A;  2PPB A;  5M3F K;  3GTK K;  4BY1 K;  3HOY K;  4Y7N C;  2CFA A;  1DCP A;  3V4G A;  3G4C A;  3N0B A;  3PO3 K;  2JA7 A;  1IL2 A;  1VJE A;  2EBB A;  3A8I A;  3GTJ K;  4MEX A;  4BY1 C;  3GTK C;  3HOY C;  1O29 A;  5DM6 S;  3WOD A;  4QIW L;  3PO3 C;  4GZY A;  2V6T A;  5L46 A;  2YU9 C;  1DD5 A;  1PJ5 A;  3GTJ C;  3HOX K;  4YFN A;  1ZQ1 C;  2FQT A;  2KXY A;  4LK0 A;  2YU9 A;  2E2H K;  2NVY C;  3TFJ A;  3VA7 A;  4WJ3 M;  3GTJ A;  4P9S A;  1WCM A;  2PA8 L;  1IW7 A;  1R9T A;  1YNN A;  4A3D C;  1WQF A;  2NVY A;  4BBS K;  1XXC A;  3T02 A;  4KB2 A;  1O27 A;  1SMY A;  3S1N K;  3PO2 K;  1BDF A;  4PAB A;  1O26 A;  3G4A A;  3HOV K;  3FKI K;  3I4N K;  1O24 A;  3S16 K;  1WOR A;  4YFK A;  4WFB S;  4A3J K;  3HOV C;  2JA8 K;  3AQO A;  3I4N C;  3S1Q K;  4C3I K;  1AB4 A;  4LOW A;  2XCR B;  3H3V L;  3S16 C;  2R93 C;  2R92 K;  4A3J C;  4G0W A;  3AD9 C;  4A3E C;  4G0V A;  4Q5S A;  1WQG A;  3ADA C;  2R93 A;  2D6F C;  2RGR A;  5FLM K;  4G7H A;  2Y0S L;  3GEI A;  5IOR A;  4OIR A;  4QJV B;  3LAJ A;  3S14 C;  4ILD A;  1Y1W K;  5FLM C;  1WIH A;  3JST A;  4FZB A;  5FJ8 K;  1UV7 A;  1XZP A;  4XLN A;  1J6W A;  3GTP K;  4KAS A;  1INN A;  2KQ1 A;  1JQW A;  2W7V A;  2NVQ C;  1Y1W C;  3M3Y C;  1Y1V K;  4A3M K;  4A3I C;  1I3Q K;  1VH2 A;  1YX2 A;  3SZY A;  3N3Y A;  4A3L K;  3PIP S;  2VUM K;  4QIW D;  1ZBS A;  3S15 K;  1Y1V C;  1TWF C;  1I50 C;  4A3M C;  5C3E K;  4A3L C;  2GSU A;  3MML B;  4GTL A;  2VUM C;  3PIO S;  3S1M K;  1WQH A;  3S15 C;  4LQY A;  1Y1V A;  3H0G K;  1J6X A;  1TWF A;  1I50 A;  2PHC B;  5C3E C;  3S1R C;  3TFH A;  5D4D A;  4NOI A;  4IOA S;  2Y3P A;  4A3G K;  4MQ9 A;  3SZZ A;  4WCE S;  3RZD K;  5M5X K;  1WOO A;  4A3F K;  4A3G C;  3LYW A;  3HKZ L;  3NUH A;  2NVX K;  3RZD C;  3S17 K;  5HL7 S;  4A3C K;  2BE5 A;  4A3F C;  4G7Z A;  4A3B K;  3N0C A;  5IYC K;  4BXX K;  5IOT A;  3ORE A;  2A68 A;  4A3K K;  2PMZ L;  4A3C C;  3GIR A; 
#chains in the Genus database with same CATH homology
 4C3H K;  3GTQ K;  3S1M C;  4C2M K;  3HKZ D;  3I4N K;  5IYD K;  5M5Y K;  2PA8 D;  1TWC K;  1XPP A;  4A3B C;  3H0G C;  3GTO K;  3S16 K;  4YFK A;  5IYC C;  4A3J K;  5TMC A;  2E2J K;  2B63 K;  3HOV C;  2JA8 K;  4C3H C;  1TWH C;  4XLP A;  3GTQ C;  3I4N C;  4A3C C;  2NVQ K;  4X6A K;  3RZO K;  1K83 K;  4C3I K;  3M3Y K;  1TWC C;  3H3V L;  3HOX C;  3S1Q K;  1I6V A;  3S16 C;  2JA5 K;  2R93 C;  2R92 K;  4KN7 A;  2JA7 K;  4A3J C;  2B63 C;  4A93 C;  5IYB K;  4A3I K;  2JA6 K;  5C44 C;  2E2H C;  1SFO K;  2Y0S D;  4A3E C;  4Q5S A;  5M3M K;  3GTG K;  3HOW K;  4X6A C;  4XSZ A;  4OIO A;  1K83 C;  3RZO C;  5M5W K;  3S2D K;  2A6E A;  1TWF K;  1I50 K;  2WAQ L;  2NVX C;  2CW0 A;  2JA7 C;  3S17 C;  4AYB L;  2JA6 C;  3CQZ C;  4KN4 A;  5TMF A;  4QJV A;  4BBS C;  5FLM K;  3HOZ K;  3I4M K;  4G7H A;  5C4X C;  3K7A K;  5IP7 K;  2Y0S L;  3DXJ A;  3S2H K;  2A69 A;  4XSX A;  4YFX A;  4OIR A;  3S1N C;  3FKI K;  4BXX C;  3EQL A;  5C4J C;  3PO2 C;  4G7O A;  3S14 C;  4QJV B;  2R7Z K;  4Y52 K;  4KMU A;  4A3K C;  4OIN A;  3FKI C;  3S1R K;  2YU9 K;  1HQM A;  2NVT K;  4C2M C;  5IYD C;  4OIQ A;  2WAQ D;  5FLM C;  1Y1W K;  3M4O K;  4AYB D;  5FJ8 K;  3GTO C;  3HOU K;  4YG2 A;  1ZYR A;  4XLN A;  2WB1 L;  1WCM K;  3S2H C;  3GTP K;  4BBR K;  2E2J C;  4Y52 C;  2R7Z C;  2JA8 C;  1R9T K;  2NVT C;  3GTM K;  4ZH4 A;  2NVQ C;  1Y1W C;  3S1Q C;  4MEY A;  4C3I C;  3M3Y C;  3M4O C;  1Y1V K;  2NVY K;  4Y7N K;  3HOU C;  4LJZ A;  2JA5 C;  1WCM C;  2R92 C;  4A3M K;  4BBR C;  4Q4Z A;  5IYB C;  4LK1 A;  4A3I C;  1I3Q K;  2O5J A;  4C3J K;  4A3L K;  3HOW C;  1R9T C;  1SFO C;  2WB1 D;  3GTM C;  3GTG C;  2PPB A;  5M3F K;  2VUM K;  3GTL K;  3GTK K;  4BY1 K;  3HOY K;  4QIW D;  4Y7N C;  3S15 K;  4A3D K;  1Y1V C;  3S2D C;  2O5I A;  1TWG K;  2E2I K;  1TWF C;  1I50 C;  4LLG A;  4A3M C;  3PO3 K;  5C3E K;  4C3J C;  4OIP A;  5IP9 K;  4A3L C;  3I4M C;  3HOZ C;  2VUM C;  3GTJ K;  4MEX A;  3K7A C;  4BY1 C;  3GTK C;  3HOY C;  3S15 C;  5IP7 C;  3S1M K;  2E2I C;  3H0G K;  4JK1 A;  3WOD A;  4QIW L;  3PO3 C;  4GZY A;  5C3E C;  1I6H K;  3S1R C;  5IP9 C;  2YU9 C;  3GTJ C;  5D4D A;  4NOI A;  1TWH K;  4A3G K;  4MQ9 A;  1TWA K;  3GTP C;  3HOX K;  2A6H A;  4YFN A;  2R93 K;  3RZD K;  5M5X K;  3HOV K;  1I6H C;  4A93 K;  4LK0 A;  5C44 K;  2E2H K;  2NVY C;  4A3E K;  4BY7 K;  4A3F K;  4A3G C;  1TWA C;  2PMZ D;  3HKZ L;  2NVX K;  1I3Q C;  3RZD C;  2PA8 L;  3S17 K;  1IW7 A;  3GTL C;  1YNN A;  4A3C K;  2BE5 A;  3CQZ K;  1YNJ A;  4A3D C;  4BY7 C;  4BBS K;  4A3F C;  1TWG C;  4G7Z A;  5C4X K;  4A3B K;  1SMY A;  5IYC K;  3S1N K;  4BXX K;  5C4J K;  3PO2 K;  1BDF A;  3S14 K;  2A68 A;  4A3K K;  2PMZ L;  3H3V D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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