2NYFA

Crystal structure of phenylalanine ammonia-lyase from nostoc punctiforme
Total Genus 192
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
192
sequence length
541
structure length
510
Chain Sequence
SIVTVGDRNLTIDEVVNVARHGTQVRLTDNADVIRGVQASCDYINNAVETAISREQAAELQTNLIWFLKSGAGNKLSLADVRAAMLLRANSHLYGASGIRLELIQRIETFLNAGVTPHVYEFGSIGDLVPLSYITGALIGLDPSFTVDFDGKEMDAVTALSRLGLPKLQLQPKEGLAMMNGTSVMTGIAANCVYDAKVLLALTMGVHALAIQGLYGTNQSFHPFIHQCKPHPGQLWTADQMFSLLKDSSLVREEQDRYSLRCLAQFIGPIVDGVSEITKQIEVEMNSVTDNPLIDVENQVSYHGGNFLGQYVGVTMDRLRYYIGLLAKHIDVQIALLVSPEFSNGLPPSLVGNSDRKVNMGLKGLQISGNSIMPLLSFYGNSLADRFPTHAEQFNQNINSQGYISANLTRRSVDIFQNYMAIALMFGVQAVDLRTYKMKGHYDARTCLSPNTVQLYTAVCEVVGKPLTSVRPYIWNDNEQCLDEHIARISADIAGGGLIVQAVEHIFSSL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Discovery of Two Cyanobacterial Phenylalanine Ammonia Lyases: Kinetic and Structural Characterization.
pubmed doi rcsb
molecule tags Lyase
source organism Nostoc punctiforme
molecule keywords Nostoc punctiforme phenylalanine ammonia lyase
total genus 192
structure length 510
sequence length 541
ec nomenclature ec 4.3.1.24: Phenylalanine ammonia-lyase.
pdb deposition date 2006-11-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 2nyfA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2nyfA02
1VDKA 1JSWA 4BABA 1GKJA 4C5SA 1EB4A 3OCFA 1XWOA 2O7FA 1TJ7A 1C3CA 2PTRA 4NLEA 1HY0A 5EYTA 1KQ7A 2O78A 1GKMA 1DOFA 2YIIA 1U15A 2QGAB 4NSLA 3RD8A 1TJVA 4EEIA 1J3UA 2PTQA 2FUSA 3QBPA 4EFCA 2HVGA 2E9FA 2X75A 4HGVA 3NO9A 1GK2A 2RJRA 3UNVA 1K62A 1I0AA 1YFMA 2J91A 1TJUA 2VD6A 1FURA 1GK3A 1W27A 3NZ4A 4C5RA 4APBA 4FFXA 1U16A 2NYFA 1AUWA 1DCNA 2O7BA 2PFMA 1FUPA 2QVEA 1RE5A 2O7DA 3GZHA 1T6JA 2PTSA 4ADLA 2OHYA 5D6BA 1FUQA 3E04A 2RJSA 3CZOA 4CQ5A 3OCEA 3TV2A 3BHGA 1YISA 3RRPA 1Y2MA 4ADMA 3R6VA 1C3UA 2O7EA 1FUOA 1TJWA 4APAA 4C5UA 4MX2A 3R6YA 4V2RA 4V2QA 2NYNA 1K7WA 3KDYA 1B8FA 3C8TA 5EYVA 5F91A 5HW2A 1Q5NA 4BAAA 2O6YA 3GTDA 4C6GA 3KDZA 1YFEA 3R6QA 1T6PA 1HY1A 4FLCA 5F92A
chains in the Genus database with same CATH superfamily
1VDKA 1JSWA 3CRVA 1XL8A 4BABA 1GKJA 2FENA 2VL7A 4C5SA 1EB4A 3OCFA 1XWOA 2O7FA 1XLYA 1TJ7A 1C3CA 2PTRA 4NLEA 1HY0A 5EYTA 1KQ7A 2O78A 1GKMA 1DOFA 2YIIA 1U15A 2QGAB 4NSLA 3RD8A 1TJVA 4EEIA 1J3UA 2PTQA 2FUSA 5M0JA 3QBPA 2VSFA 5M0IA 4EFCA 2HVGA 4A15A 2E9FA 2X75A 4HGVA 1XL7A 3NO9A 1GK2A 2RJRA 3UNVA 1K62A 1I0AA 1YFMA 2J91A 1TJUA 4WNLA 2VD6A 1FURA 1GK3A 1W27A 3NZ4A 4C5RA 4APBA 4FFXA 1U16A 2NYFA 1AUWA 1DCNA 2O7BA 2PFMA 1FUPA 2QVEA 2FELA 1RE5A 2O7DA 3GZHA 1T6JA 2PTSA 4ADLA 1XMDA 3CRW1 2OHYA 5D6BA 1FUQA 3E04A 2RJSA 3CZOA 4CQ5A 3OCEA 3TV2A 3BHGA 1YISA 3RRPA 1Y2MA 4ADMA 3R6VA 1C3UA 2O7EA 1FUOA 1TJWA 4APAA 4C5UA 4MX2A 3R6YA 4V2RA 4V2QA 2NYNA 1K7WA 3KDYA 1B8FA 3C8TA 5EYVA 5F91A 5HW2A 1Q5NA 4BAAA 2O6YA 3GTDA 5H8WA 4C6GA 3KDZA 1YFEA 1XMCA 3R6QA 1T6PA 1HY1A 4FLCA 5F92A
chains in the Genus database with same CATH topology
1VDKA 1JSWA 4BABA 1GKJA 4C5SA 1EB4A 3OCFA 1XWOA 2O7FA 1TJ7A 1C3CA 2PTRA 4NLEA 1HY0A 5EYTA 1KQ7A 2O78A 1GKMA 1DOFA 2YIIA 1U15A 2QGAB 4NSLA 3RD8A 1TJVA 4EEIA 1J3UA 2PTQA 2FUSA 3QBPA 4EFCA 2HVGA 2E9FA 2X75A 4HGVA 3NO9A 1GK2A 2RJRA 3UNVA 1K62A 1I0AA 1YFMA 2J91A 1TJUA 2VD6A 1FURA 1GK3A 1W27A 3NZ4A 4C5RA 4APBA 4FFXA 1U16A 2NYFA 1AUWA 1DCNA 2O7BA 2PFMA 1FUPA 2QVEA 1RE5A 2O7DA 3GZHA 1T6JA 2PTSA 4ADLA 2OHYA 5D6BA 1FUQA 3E04A 2RJSA 3CZOA 4CQ5A 3OCEA 3TV2A 3BHGA 1YISA 3RRPA 1Y2MA 4ADMA 3R6VA 1C3UA 2O7EA 1FUOA 1TJWA 4APAA 4C5UA 4MX2A 3R6YA 4V2RA 4V2QA 2NYNA 1K7WA 3KDYA 1B8FA 3C8TA 5EYVA 5F91A 5HW2A 1Q5NA 4BAAA 2O6YA 3GTDA 4C6GA 3KDZA 1YFEA 3R6QA 1T6PA 1HY1A 4FLCA 5F92A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VDK A;  1JSW A;  4BAB A;  1GKJ A;  4C5S A;  1EB4 A;  3OCF A;  1XWO A;  2O7F A;  1TJ7 A;  1C3C A;  2PTR A;  4NLE A;  1HY0 A;  5EYT A;  1KQ7 A;  2O78 A;  1GKM A;  1DOF A;  2YII A;  1U15 A;  2QGA B;  4NSL A;  3RD8 A;  1TJV A;  4EEI A;  1J3U A;  2PTQ A;  2FUS A;  3QBP A;  4EFC A;  2HVG A;  2E9F A;  2X75 A;  4HGV A;  3NO9 A;  1GK2 A;  2RJR A;  3UNV A;  1K62 A;  1I0A A;  1YFM A;  2J91 A;  1TJU A;  2VD6 A;  1FUR A;  1GK3 A;  1W27 A;  3NZ4 A;  4C5R A;  4APB A;  4FFX A;  1U16 A;  2NYF A;  1AUW A;  1DCN A;  2O7B A;  2PFM A;  1FUP A;  2QVE A;  1RE5 A;  2O7D A;  3GZH A;  1T6J A;  2PTS A;  4ADL A;  2OHY A;  5D6B A;  1FUQ A;  3E04 A;  2RJS A;  3CZO A;  4CQ5 A;  3OCE A;  3TV2 A;  3BHG A;  1YIS A;  3RRP A;  1Y2M A;  4ADM A;  3R6V A;  1C3U A;  2O7E A;  1FUO A;  1TJW A;  4APA A;  4C5U A;  4MX2 A;  3R6Y A;  4V2R A;  4V2Q A;  2NYN A;  1K7W A;  3KDY A;  1B8F A;  3C8T A;  5EYV A;  5F91 A;  5HW2 A;  1Q5N A;  4BAA A;  2O6Y A;  3GTD A;  4C6G A;  3KDZ A;  1YFE A;  3R6Q A;  1T6P A;  1HY1 A;  4FLC A;  5F92 A; 
#chains in the Genus database with same CATH topology
 1VDK A;  1JSW A;  3CRV A;  1XL8 A;  4BAB A;  1GKJ A;  2FEN A;  2VL7 A;  4C5S A;  1EB4 A;  3OCF A;  1XWO A;  2O7F A;  1XLY A;  1TJ7 A;  1C3C A;  2PTR A;  4NLE A;  1HY0 A;  5EYT A;  1KQ7 A;  2O78 A;  1GKM A;  1DOF A;  2YII A;  1U15 A;  2QGA B;  4NSL A;  3RD8 A;  1TJV A;  4EEI A;  1J3U A;  2PTQ A;  2FUS A;  5M0J A;  3QBP A;  2VSF A;  5M0I A;  4EFC A;  2HVG A;  4A15 A;  2E9F A;  2X75 A;  4HGV A;  1XL7 A;  3NO9 A;  1GK2 A;  2RJR A;  3UNV A;  1K62 A;  1I0A A;  1YFM A;  2J91 A;  1TJU A;  4WNL A;  2VD6 A;  1FUR A;  1GK3 A;  1W27 A;  3NZ4 A;  4C5R A;  4APB A;  4FFX A;  1U16 A;  2NYF A;  1AUW A;  1DCN A;  2O7B A;  2PFM A;  1FUP A;  2QVE A;  2FEL A;  1RE5 A;  2O7D A;  3GZH A;  1T6J A;  2PTS A;  4ADL A;  1XMD A;  3CRW 1;  2OHY A;  5D6B A;  1FUQ A;  3E04 A;  2RJS A;  3CZO A;  4CQ5 A;  3OCE A;  3TV2 A;  3BHG A;  1YIS A;  3RRP A;  1Y2M A;  4ADM A;  3R6V A;  1C3U A;  2O7E A;  1FUO A;  1TJW A;  4APA A;  4C5U A;  4MX2 A;  3R6Y A;  4V2R A;  4V2Q A;  2NYN A;  1K7W A;  3KDY A;  1B8F A;  3C8T A;  5EYV A;  5F91 A;  5HW2 A;  1Q5N A;  4BAA A;  2O6Y A;  3GTD A;  5H8W A;  4C6G A;  3KDZ A;  1YFE A;  1XMC A;  3R6Q A;  1T6P A;  1HY1 A;  4FLC A;  5F92 A; 
#chains in the Genus database with same CATH homology
 1VDK A;  1JSW A;  4BAB A;  1GKJ A;  4C5S A;  1EB4 A;  3OCF A;  1XWO A;  2O7F A;  1TJ7 A;  1C3C A;  2PTR A;  4NLE A;  1HY0 A;  5EYT A;  1KQ7 A;  2O78 A;  1GKM A;  1DOF A;  2YII A;  1U15 A;  2QGA B;  4NSL A;  3RD8 A;  1TJV A;  4EEI A;  1J3U A;  2PTQ A;  2FUS A;  3QBP A;  4EFC A;  2HVG A;  2E9F A;  2X75 A;  4HGV A;  3NO9 A;  1GK2 A;  2RJR A;  3UNV A;  1K62 A;  1I0A A;  1YFM A;  2J91 A;  1TJU A;  2VD6 A;  1FUR A;  1GK3 A;  1W27 A;  3NZ4 A;  4C5R A;  4APB A;  4FFX A;  1U16 A;  2NYF A;  1AUW A;  1DCN A;  2O7B A;  2PFM A;  1FUP A;  2QVE A;  1RE5 A;  2O7D A;  3GZH A;  1T6J A;  2PTS A;  4ADL A;  2OHY A;  5D6B A;  1FUQ A;  3E04 A;  2RJS A;  3CZO A;  4CQ5 A;  3OCE A;  3TV2 A;  3BHG A;  1YIS A;  3RRP A;  1Y2M A;  4ADM A;  3R6V A;  1C3U A;  2O7E A;  1FUO A;  1TJW A;  4APA A;  4C5U A;  4MX2 A;  3R6Y A;  4V2R A;  4V2Q A;  2NYN A;  1K7W A;  3KDY A;  1B8F A;  3C8T A;  5EYV A;  5F91 A;  5HW2 A;  1Q5N A;  4BAA A;  2O6Y A;  3GTD A;  4C6G A;  3KDZ A;  1YFE A;  3R6Q A;  1T6P A;  1HY1 A;  4FLC A;  5F92 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...