2NYMC

Crystal structure of protein phosphatase 2a (pp2a) with c-terminus truncated catalytic subunit
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
293
structure length
293
Chain Sequence
DEKVFTKELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the Protein Phosphatase 2A Holoenzyme.
pubmed doi rcsb
molecule keywords Protein phosphatase 2
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
total genus 88
structure length 293
sequence length 293
chains with identical sequence F
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2006-11-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00149 Metallophos Calcineurin-like phosphoesterase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 2nymC00
3H67A 1WARA 3HVQA 4ZVZA 3IB7A 3QG5C 4KBPA 2P6BA 4LTYA 5JPEA 1HO5A 1USHA 3C5WC 4F0ZA 2QJCA 5INBA 3ZTVA 1TCOA 2R17A 3H69A 4IYPC 2DFJA 3K7VC 3RQZA 1T70A 3C9FA 2QFPA 1S70A 3DSDA 3EGHA 4H2FA 4UWQA 5IOHA 4TUGA 2WDDA 2HY1A 3CK2A 4G9JA 1FJMA 4ORCA 3AV0A 4M0VA 2IE3C 1KBPA 3H64A 4J6OA 2USHA 3RL5A 4UT3B 3E7BA 3THNA 5F3WA 1U32A 4HD0A 4V0WA 4KKZA 4TUIA 3P71C 1G5BA 3JYFA 4UT3A 4OR9A 3AUZA 3ZU0A 3H63A 4DSYA 2WDCA 3E7AA 4H2GA 4H1YP 1OIEA 4DHLA 4IL1A 1HP1A 3H60A 4MP0A 4DT2A 3H68A 3IB8A 3H61A 1S8EA 4H2BA 1MF8A 3N5UA 2CV9A 2GJUA 2NYLC 3QFKA 3V4YA 3QFMA 1HPUA 1SU1A 1S3NA 3QFOA 4Q7FA 1S3LA 4V0VA 4FBQA 3ICFA 3H62B 5HPEA 1OIDA 2NPPC 2XMOA 3RL4A 2JOGA 5DNYA 2Z06A 2BQ8X 2Q8UA 4ORBA 1XM7A 5GTUA 5JPFA 1W24A 1Z2WA 3KBPA 4WWLA 2O8GA 1WAO1 4FBWA 2Z72A 3RL3A 4H1SA 4JA7A 4B2OA 4V0XA 1NNWA 2Z1AA 1UF3A 4JA9A 4XPNA 1IT6A 1S3MA 3IVEA 4ZX2A 4NZVA 5J28A 1QFCA 2O8AA 1QHWA 5EQVA 4H2IA 3PSNA 4FCXA 1JK7A 3K7WC 3T1IA 4LU9A 5B8IA 2IAEC 2A22A 3FGAC 4O43A 2IE4C 2BDXA 1II7A 4MOVA 2NYMC 2WDFA 3EGGA 1M63A 1Z2XA 4YKEA 5C1VA 4O4KA 3GVEA 5JJTA 4ORAA 4LACC 3TGHA 1AUIA 3PSOA 1UTEA 2HYPA 2HYOA 4I5NC 4I5LC 4O24A 3THOB 2QFRA 2WDEA 3DW8C 3DSCA 2ZBMA 2YVTA 3LL8A 4MOYA 3QFNA 2NXFA 2KKNA 1S95A 1V73A 1T71A 1OI8A 2BCDA 1XZWA 4O5GA 4UT2A 3H66A 4FBKA 2AHDA 3IVDA
chains in the Genus database with same CATH superfamily
3H67A 1WARA 3HVQA 2DXNA 2YEQA 3IB7A 3QG5C 4KBPA 2P6BA 4LTYA 4ZVZA 5JPEA 1HO5A 1USHA 3C5WC 4F0ZA 2QJCA 5INBA 3ZTVA 1TCOA 2R17A 3H69A 4IYPC 2DFJA 3K7VC 3RQZA 1T70A 3C9FA 2QFPA 1S70A 3DSDA 3EGHA 4H2FA 4UWQA 5IOHA 4TUGA 2WDDA 2HY1A 3CK2A 4G9JA 1FJMA 4ORCA 3AV0A 4M0VA 2IE3C 3D03A 1KBPA 3H64A 4J6OA 2USHA 3RL5A 4UT3B 3E7BA 3THNA 5F3WA 1U32A 4HD0A 4V0WA 4KKZA 4TUIA 3P71C 1G5BA 3JYFA 4UT3A 4OR9A 3AUZA 3ZU0A 3H63A 4DSYA 2WDCA 3E7AA 4H2GA 4H1YP 1OIEA 4DHLA 4IL1A 1HP1A 3H60A 4MP0A 4DT2A 3H68A 3IB8A 3H61A 1S8EA 4H2BA 1MF8A 3N5UA 2CV9A 2GJUA 2NYLC 3QFKA 3V4YA 2ZO9B 3QFMA 1HPUA 1SU1A 1S3NA 3QFOA 4Q7FA 1S3LA 4V0VA 4FBQA 3ICFA 2ZOAA 3H62B 5HPEA 1OIDA 2NPPC 2XMOA 3RL4A 2JOGA 5DNYA 2Z06A 2BQ8X 2Q8UA 4ORBA 1XM7A 5GTUA 5JPFA 1W24A 1Z2WA 3KBPA 4WWLA 2O8GA 1WAO1 4FBWA 2Z72A 3RL3A 4H1SA 4JA7A 4B2OA 4V0XA 1NNWA 1UF3A 2Z1AA 4JA9A 4XPNA 1IT6A 1S3MA 3IVEA 4ZX2A 4NZVA 5J28A 1QFCA 2O8AA 1QHWA 5EQVA 4H2IA 3PSNA 4FCXA 1JK7A 3K7WC 3T1IA 4LU9A 5B8IA 2IAEC 2A22A 2DXLA 3FGAC 4O43A 2IE4C 2BDXA 1II7A 4MOVA 2NYMC 2WDFA 3E0JA 3EGGA 1M63A 1Z2XA 4YKEA 5C1VA 4O4KA 3GVEA 5JJTA 4ORAA 4LACC 3TGHA 1AUIA 3PSOA 1UTEA 2HYPA 2HYOA 4I5NC 4I5LC 4O24A 3THOB 2QFRA 2WDEA 3DW8C 3DSCA 2ZBMA 2YVTA 3LL8A 4MOYA 3QFNA 2NXFA 2KKNA 1S95A 1V73A 1T71A 1OI8A 2BCDA 1XZWA 4O5GA 4UT2A 3H66A 4FBKA 2AHDA 3FLOA 3IVDA
chains in the Genus database with same CATH topology
3H67A 1WARA 3HVQA 2DXNA 2YEQA 3IB7A 3QG5C 4KBPA 2P6BA 4LTYA 4ZVZA 5JPEA 1HO5A 1USHA 3C5WC 4F0ZA 2QJCA 5INBA 3ZTVA 1TCOA 2R17A 3H69A 4IYPC 2DFJA 3K7VC 3RQZA 1T70A 3C9FA 2QFPA 1S70A 3DSDA 3EGHA 4H2FA 4UWQA 5IOHA 4TUGA 2WDDA 2HY1A 3CK2A 4G9JA 1FJMA 4ORCA 3AV0A 4M0VA 2IE3C 3D03A 1KBPA 3H64A 4J6OA 2USHA 3RL5A 4UT3B 3E7BA 3THNA 5F3WA 1U32A 4HD0A 4V0WA 4KKZA 4TUIA 3P71C 1G5BA 3JYFA 4UT3A 4OR9A 3AUZA 3ZU0A 3H63A 4DSYA 2WDCA 3E7AA 4H2GA 4H1YP 1OIEA 4DHLA 4IL1A 1HP1A 3H60A 4MP0A 4DT2A 3H68A 3IB8A 3H61A 1S8EA 4H2BA 1MF8A 3N5UA 2CV9A 2GJUA 2NYLC 3QFKA 3V4YA 2ZO9B 3QFMA 1HPUA 1SU1A 1S3NA 3QFOA 4Q7FA 1S3LA 4V0VA 4FBQA 3ICFA 2ZOAA 3H62B 5HPEA 1OIDA 2NPPC 2XMOA 3RL4A 2JOGA 5DNYA 2Z06A 2BQ8X 2Q8UA 4ORBA 1XM7A 5GTUA 5JPFA 1W24A 1Z2WA 3KBPA 4WWLA 2O8GA 1WAO1 4FBWA 2Z72A 3RL3A 4H1SA 4JA7A 4B2OA 4V0XA 1NNWA 1UF3A 2Z1AA 4JA9A 4XPNA 1IT6A 1S3MA 3IVEA 4ZX2A 4NZVA 5J28A 1QFCA 2O8AA 1QHWA 5EQVA 4H2IA 3PSNA 4FCXA 1JK7A 3K7WC 3T1IA 4LU9A 5B8IA 2IAEC 2A22A 2DXLA 3FGAC 4O43A 2IE4C 2BDXA 1II7A 4MOVA 2NYMC 2WDFA 3E0JA 3EGGA 1M63A 1Z2XA 4YKEA 5C1VA 4O4KA 3GVEA 5JJTA 4ORAA 4LACC 3TGHA 1AUIA 3PSOA 1UTEA 2HYPA 2HYOA 4I5NC 4I5LC 4O24A 3THOB 2QFRA 2WDEA 3DW8C 3DSCA 2ZBMA 2YVTA 3LL8A 4MOYA 3QFNA 2NXFA 2KKNA 1S95A 1V73A 1T71A 1OI8A 2BCDA 1XZWA 4O5GA 4UT2A 3H66A 4FBKA 2AHDA 3FLOA 3IVDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3H67 A;  1WAR A;  3HVQ A;  4ZVZ A;  3IB7 A;  3QG5 C;  4KBP A;  2P6B A;  4LTY A;  5JPE A;  1HO5 A;  1USH A;  3C5W C;  4F0Z A;  2QJC A;  5INB A;  3ZTV A;  1TCO A;  2R17 A;  3H69 A;  4IYP C;  2DFJ A;  3K7V C;  3RQZ A;  1T70 A;  3C9F A;  2QFP A;  1S70 A;  3DSD A;  3EGH A;  4H2F A;  4UWQ A;  5IOH A;  4TUG A;  2WDD A;  2HY1 A;  3CK2 A;  4G9J A;  1FJM A;  4ORC A;  3AV0 A;  4M0V A;  2IE3 C;  1KBP A;  3H64 A;  4J6O A;  2USH A;  3RL5 A;  4UT3 B;  3E7B A;  3THN A;  5F3W A;  1U32 A;  4HD0 A;  4V0W A;  4KKZ A;  4TUI A;  3P71 C;  1G5B A;  3JYF A;  4UT3 A;  4OR9 A;  3AUZ A;  3ZU0 A;  3H63 A;  4DSY A;  2WDC A;  3E7A A;  4H2G A;  4H1Y P;  1OIE A;  4DHL A;  4IL1 A;  1HP1 A;  3H60 A;  4MP0 A;  4DT2 A;  3H68 A;  3IB8 A;  3H61 A;  1S8E A;  4H2B A;  1MF8 A;  3N5U A;  2CV9 A;  2GJU A;  2NYL C;  3QFK A;  3V4Y A;  3QFM A;  1HPU A;  1SU1 A;  1S3N A;  3QFO A;  4Q7F A;  1S3L A;  4V0V A;  4FBQ A;  3ICF A;  3H62 B;  5HPE A;  1OID A;  2NPP C;  2XMO A;  3RL4 A;  2JOG A;  5DNY A;  2Z06 A;  2BQ8 X;  2Q8U A;  4ORB A;  1XM7 A;  5GTU A;  5JPF A;  1W24 A;  1Z2W A;  3KBP A;  4WWL A;  2O8G A;  1WAO 1;  4FBW A;  2Z72 A;  3RL3 A;  4H1S A;  4JA7 A;  4B2O A;  4V0X A;  1NNW A;  2Z1A A;  1UF3 A;  4JA9 A;  4XPN A;  1IT6 A;  1S3M A;  3IVE A;  4ZX2 A;  4NZV A;  5J28 A;  1QFC A;  2O8A A;  1QHW A;  5EQV A;  4H2I A;  3PSN A;  4FCX A;  1JK7 A;  3K7W C;  3T1I A;  4LU9 A;  5B8I A;  2IAE C;  2A22 A;  3FGA C;  4O43 A;  2IE4 C;  2BDX A;  1II7 A;  4MOV A;  2NYM C;  2WDF A;  3EGG A;  1M63 A;  1Z2X A;  4YKE A;  5C1V A;  4O4K A;  3GVE A;  5JJT A;  4ORA A;  4LAC C;  3TGH A;  1AUI A;  3PSO A;  1UTE A;  2HYP A;  2HYO A;  4I5N C;  4I5L C;  4O24 A;  3THO B;  2QFR A;  2WDE A;  3DW8 C;  3DSC A;  2ZBM A;  2YVT A;  3LL8 A;  4MOY A;  3QFN A;  2NXF A;  2KKN A;  1S95 A;  1V73 A;  1T71 A;  1OI8 A;  2BCD A;  1XZW A;  4O5G A;  4UT2 A;  3H66 A;  4FBK A;  2AHD A;  3IVD A; 
#chains in the Genus database with same CATH topology
 3H67 A;  1WAR A;  3HVQ A;  2DXN A;  2YEQ A;  3IB7 A;  3QG5 C;  4KBP A;  2P6B A;  4LTY A;  4ZVZ A;  5JPE A;  1HO5 A;  1USH A;  3C5W C;  4F0Z A;  2QJC A;  5INB A;  3ZTV A;  1TCO A;  2R17 A;  3H69 A;  4IYP C;  2DFJ A;  3K7V C;  3RQZ A;  1T70 A;  3C9F A;  2QFP A;  1S70 A;  3DSD A;  3EGH A;  4H2F A;  4UWQ A;  5IOH A;  4TUG A;  2WDD A;  2HY1 A;  3CK2 A;  4G9J A;  1FJM A;  4ORC A;  3AV0 A;  4M0V A;  2IE3 C;  3D03 A;  1KBP A;  3H64 A;  4J6O A;  2USH A;  3RL5 A;  4UT3 B;  3E7B A;  3THN A;  5F3W A;  1U32 A;  4HD0 A;  4V0W A;  4KKZ A;  4TUI A;  3P71 C;  1G5B A;  3JYF A;  4UT3 A;  4OR9 A;  3AUZ A;  3ZU0 A;  3H63 A;  4DSY A;  2WDC A;  3E7A A;  4H2G A;  4H1Y P;  1OIE A;  4DHL A;  4IL1 A;  1HP1 A;  3H60 A;  4MP0 A;  4DT2 A;  3H68 A;  3IB8 A;  3H61 A;  1S8E A;  4H2B A;  1MF8 A;  3N5U A;  2CV9 A;  2GJU A;  2NYL C;  3QFK A;  3V4Y A;  2ZO9 B;  3QFM A;  1HPU A;  1SU1 A;  1S3N A;  3QFO A;  4Q7F A;  1S3L A;  4V0V A;  4FBQ A;  3ICF A;  2ZOA A;  3H62 B;  5HPE A;  1OID A;  2NPP C;  2XMO A;  3RL4 A;  2JOG A;  5DNY A;  2Z06 A;  2BQ8 X;  2Q8U A;  4ORB A;  1XM7 A;  5GTU A;  5JPF A;  1W24 A;  1Z2W A;  3KBP A;  4WWL A;  2O8G A;  1WAO 1;  4FBW A;  2Z72 A;  3RL3 A;  4H1S A;  4JA7 A;  4B2O A;  4V0X A;  1NNW A;  1UF3 A;  2Z1A A;  4JA9 A;  4XPN A;  1IT6 A;  1S3M A;  3IVE A;  4ZX2 A;  4NZV A;  5J28 A;  1QFC A;  2O8A A;  1QHW A;  5EQV A;  4H2I A;  3PSN A;  4FCX A;  1JK7 A;  3K7W C;  3T1I A;  4LU9 A;  5B8I A;  2IAE C;  2A22 A;  2DXL A;  3FGA C;  4O43 A;  2IE4 C;  2BDX A;  1II7 A;  4MOV A;  2NYM C;  2WDF A;  3E0J A;  3EGG A;  1M63 A;  1Z2X A;  4YKE A;  5C1V A;  4O4K A;  3GVE A;  5JJT A;  4ORA A;  4LAC C;  3TGH A;  1AUI A;  3PSO A;  1UTE A;  2HYP A;  2HYO A;  4I5N C;  4I5L C;  4O24 A;  3THO B;  2QFR A;  2WDE A;  3DW8 C;  3DSC A;  2ZBM A;  2YVT A;  3LL8 A;  4MOY A;  3QFN A;  2NXF A;  2KKN A;  1S95 A;  1V73 A;  1T71 A;  1OI8 A;  2BCD A;  1XZW A;  4O5G A;  4UT2 A;  3H66 A;  4FBK A;  2AHD A;  3FLO A;  3IVD A; 
#chains in the Genus database with same CATH homology
 3H67 A;  1WAR A;  3HVQ A;  2DXN A;  2YEQ A;  3IB7 A;  3QG5 C;  4KBP A;  2P6B A;  4LTY A;  4ZVZ A;  5JPE A;  1HO5 A;  1USH A;  3C5W C;  4F0Z A;  2QJC A;  5INB A;  3ZTV A;  1TCO A;  2R17 A;  3H69 A;  4IYP C;  2DFJ A;  3K7V C;  3RQZ A;  1T70 A;  3C9F A;  2QFP A;  1S70 A;  3DSD A;  3EGH A;  4H2F A;  4UWQ A;  5IOH A;  4TUG A;  2WDD A;  2HY1 A;  3CK2 A;  4G9J A;  1FJM A;  4ORC A;  3AV0 A;  4M0V A;  2IE3 C;  3D03 A;  1KBP A;  3H64 A;  4J6O A;  2USH A;  3RL5 A;  4UT3 B;  3E7B A;  3THN A;  5F3W A;  1U32 A;  4HD0 A;  4V0W A;  4KKZ A;  4TUI A;  3P71 C;  1G5B A;  3JYF A;  4UT3 A;  4OR9 A;  3AUZ A;  3ZU0 A;  3H63 A;  4DSY A;  2WDC A;  3E7A A;  4H2G A;  4H1Y P;  1OIE A;  4DHL A;  4IL1 A;  1HP1 A;  3H60 A;  4MP0 A;  4DT2 A;  3H68 A;  3IB8 A;  3H61 A;  1S8E A;  4H2B A;  1MF8 A;  3N5U A;  2CV9 A;  2GJU A;  2NYL C;  3QFK A;  3V4Y A;  2ZO9 B;  3QFM A;  1HPU A;  1SU1 A;  1S3N A;  3QFO A;  4Q7F A;  1S3L A;  4V0V A;  4FBQ A;  3ICF A;  2ZOA A;  3H62 B;  5HPE A;  1OID A;  2NPP C;  2XMO A;  3RL4 A;  2JOG A;  5DNY A;  2Z06 A;  2BQ8 X;  2Q8U A;  4ORB A;  1XM7 A;  5GTU A;  5JPF A;  1W24 A;  1Z2W A;  3KBP A;  4WWL A;  2O8G A;  1WAO 1;  4FBW A;  2Z72 A;  3RL3 A;  4H1S A;  4JA7 A;  4B2O A;  4V0X A;  1NNW A;  1UF3 A;  2Z1A A;  4JA9 A;  4XPN A;  1IT6 A;  1S3M A;  3IVE A;  4ZX2 A;  4NZV A;  5J28 A;  1QFC A;  2O8A A;  1QHW A;  5EQV A;  4H2I A;  3PSN A;  4FCX A;  1JK7 A;  3K7W C;  3T1I A;  4LU9 A;  5B8I A;  2IAE C;  2A22 A;  2DXL A;  3FGA C;  4O43 A;  2IE4 C;  2BDX A;  1II7 A;  4MOV A;  2NYM C;  2WDF A;  3E0J A;  3EGG A;  1M63 A;  1Z2X A;  4YKE A;  5C1V A;  4O4K A;  3GVE A;  5JJT A;  4ORA A;  4LAC C;  3TGH A;  1AUI A;  3PSO A;  1UTE A;  2HYP A;  2HYO A;  4I5N C;  4I5L C;  4O24 A;  3THO B;  2QFR A;  2WDE A;  3DW8 C;  3DSC A;  2ZBM A;  2YVT A;  3LL8 A;  4MOY A;  3QFN A;  2NXF A;  2KKN A;  1S95 A;  1V73 A;  1T71 A;  1OI8 A;  2BCD A;  1XZW A;  4O5G A;  4UT2 A;  3H66 A;  4FBK A;  2AHD A;  3FLO A;  3IVD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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