2O02A

Phosphorylation independent interactions between 14-3-3 and exoenzyme s: from structure to pathogenesis
Total Genus 99
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
230
structure length
224
Chain Sequence
MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Phosphorylation-independent interaction between 14-3-3 and exoenzyme S: from structure to pathogenesis
pubmed doi rcsb
molecule tags Protein binding/toxin
source organism Homo sapiens
molecule keywords 14-3-3 protein zeta/delta
total genus 99
structure length 224
sequence length 230
chains with identical sequence B
ec nomenclature
pdb deposition date 2006-11-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00244 14-3-3 14-3-3 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.190.20 Mainly Alpha Up-down Bundle Delta-Endotoxin; domain 1 14-3-3 domain 2o02A00
4J6SA 5LX2A 4DHPA 2O02A 4FJ3A 1O9CA 4DX0A 1O9FA 3SMLA 4DHSA 1YWTA 3UX0A 4O46A 3CU8A 2C1NA 1YZ5A 1QJAA 5J31A 3LW1A 5HF3A 5LVZA 5LHOA 4DHUA 3SMOA 3SMMA 4GNTA 4E2EA 4DHOA 4N7GA 1IB1A 3RDHA 3T0MA 5D3FA 3SMNA 1A38A 2NPMA 3UALA 5EXAA 4DHTA 3O8IA 1QJBA 3EFZA 4DAUA 4JDDA 2C74A 3IQUA 4BG6A 4N84A 4Y5IA 4DHMA 4DNKA 5LU1A 5D3EA 2BQ0A 4FL5A 4FR3A 5F74A 3P1PA 4IHLA 3NKXA 4DHNA 3T0LA 2O8PA 3SPRA 3P1QA 5D2DA 3M50A 4N7YA 4F7RA 1O9DA 4WRQA 3IQJA 5EWZA 1A4OA 4DATA 4IEAA 2BR9A 5IQPA 2BTPA 1A37A 3P1RA 3IQVA 4DHQA 3M51A 5BY9A 4HKCA 2O98A 3AXYC 2WH0A 3SP5A 3U9XA 2V7DA 4ZDRA 2B05A 3P1NA 2C63A 2C1JA 4DHRA 5LU2A 4JC3A 3SMKA 2C23A 1O9EA 3UZDA 4QLIA 3P1SA 3P1OA 4ZQ0A 3UBWA 5BTVA 4Y3BA 3MHRA 4Y32A 3E6YA
chains in the Genus database with same CATH superfamily
1URJA 4J6SA 5LX2A 4DHPA 2O02A 4FJ3A 1O9CA 4DX0A 1O9FA 3SMLA 4DHSA 1YWTA 3UX0A 4O46A 3CU8A 1YZ5A 2C1NA 4D8MA 1QJAA 5J31A 3LW1A 4QX0A 3EB7A 5HF3A 3CQCA 1JI6A 5LVZA 5LHOA 4DHUA 3SMOA 3SMMA 4GNTA 4E2EA 4DHOA 4N7GA 1IB1A 3RDHA 3T0MA 5D3FA 3SMNA 1CIYA 1A38A 2NPMA 3UALA 5EXAA 4DHTA 3O8IA 1QJBA 3EFZA 4DAUA 2C9KA 4JDDA 2C74A 3IQUA 4BG6A 4N84A 4Y5IA 4DHMA 4ARYA 4DNKA 5LU1A 5D3EA 2BQ0A 4FL5A 4FR3A 5F74A 3P1PA 4IHLA 3NKXA 4DHNA 3T0LA 2O8PA 3SPRA 3P1QA 1S2XA 5D2DA 3M50A 4N7YA 4F7RA 1O9DA 4WRQA 3IQJA 5EWZA 1A4OA 4DATA 4IEAA 2BR9A 3ZHEB 4QX1A 5IQPA 2BTPA 1A37A 4ARXA 3P1RA 3IQVA 4DHQA 4MOAA 3M51A 5BY9A 4HKCA 2O98A 1DLCA 1I5PA 3AXYC 2WH0A 3CQGA 3SP5A 4QX3A 3U9XA 4W8JA 2V7DA 4ZDRA 2B05A 3P1NA 2C63A 2C1JA 4DHRA 5LU2A 1W99A 4JC3A 3SMKA 2C23A 1O9EA 4QX2A 3UZDA 4QLIA 3P1SA 3P1OA 4ZQ0A 3UBWA 5BTVA 3I4RA 4Y3BA 3X0UA 3MHRA 4Y32A 3E6YA
chains in the Genus database with same CATH topology
4J6SA 5LX2A 4DHPA 2O02A 4FJ3A 1O9CA 4DX0A 1O9FA 3SMLA 4DHSA 1YWTA 3UX0A 4O46A 3CU8A 2C1NA 1YZ5A 1QJAA 5J31A 3LW1A 5HF3A 5LVZA 5LHOA 4DHUA 3SMOA 3SMMA 4GNTA 4E2EA 4DHOA 4N7GA 1IB1A 3RDHA 3T0MA 5D3FA 3SMNA 1A38A 2NPMA 3UALA 5EXAA 4DHTA 3O8IA 1QJBA 3EFZA 4DAUA 4JDDA 2C74A 3IQUA 4BG6A 4N84A 4Y5IA 4DHMA 4DNKA 5LU1A 5D3EA 2BQ0A 4FL5A 4FR3A 5F74A 3P1PA 4IHLA 3NKXA 4DHNA 3T0LA 2O8PA 3SPRA 3P1QA 5D2DA 3M50A 4N7YA 4F7RA 1O9DA 4WRQA 3IQJA 5EWZA 1A4OA 4DATA 4IEAA 2BR9A 5IQPA 2BTPA 1A37A 3P1RA 3IQVA 4DHQA 3M51A 5BY9A 4HKCA 2O98A 3AXYC 2WH0A 3SP5A 3U9XA 2V7DA 4ZDRA 2B05A 3P1NA 2C63A 2C1JA 4DHRA 5LU2A 4JC3A 3SMKA 2C23A 1O9EA 3UZDA 4QLIA 3P1SA 3P1OA 4ZQ0A 3UBWA 5BTVA 4Y3BA 3MHRA 4Y32A 3E6YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4J6S A;  5LX2 A;  4DHP A;  2O02 A;  4FJ3 A;  1O9C A;  4DX0 A;  1O9F A;  3SML A;  4DHS A;  1YWT A;  3UX0 A;  4O46 A;  3CU8 A;  2C1N A;  1YZ5 A;  1QJA A;  5J31 A;  3LW1 A;  5HF3 A;  5LVZ A;  5LHO A;  4DHU A;  3SMO A;  3SMM A;  4GNT A;  4E2E A;  4DHO A;  4N7G A;  1IB1 A;  3RDH A;  3T0M A;  5D3F A;  3SMN A;  1A38 A;  2NPM A;  3UAL A;  5EXA A;  4DHT A;  3O8I A;  1QJB A;  3EFZ A;  4DAU A;  4JDD A;  2C74 A;  3IQU A;  4BG6 A;  4N84 A;  4Y5I A;  4DHM A;  4DNK A;  5LU1 A;  5D3E A;  2BQ0 A;  4FL5 A;  4FR3 A;  5F74 A;  3P1P A;  4IHL A;  3NKX A;  4DHN A;  3T0L A;  2O8P A;  3SPR A;  3P1Q A;  5D2D A;  3M50 A;  4N7Y A;  4F7R A;  1O9D A;  4WRQ A;  3IQJ A;  5EWZ A;  1A4O A;  4DAT A;  4IEA A;  2BR9 A;  5IQP A;  2BTP A;  1A37 A;  3P1R A;  3IQV A;  4DHQ A;  3M51 A;  5BY9 A;  4HKC A;  2O98 A;  3AXY C;  2WH0 A;  3SP5 A;  3U9X A;  2V7D A;  4ZDR A;  2B05 A;  3P1N A;  2C63 A;  2C1J A;  4DHR A;  5LU2 A;  4JC3 A;  3SMK A;  2C23 A;  1O9E A;  3UZD A;  4QLI A;  3P1S A;  3P1O A;  4ZQ0 A;  3UBW A;  5BTV A;  4Y3B A;  3MHR A;  4Y32 A;  3E6Y A; 
#chains in the Genus database with same CATH topology
 1URJ A;  4J6S A;  5LX2 A;  4DHP A;  2O02 A;  4FJ3 A;  1O9C A;  4DX0 A;  1O9F A;  3SML A;  4DHS A;  1YWT A;  3UX0 A;  4O46 A;  3CU8 A;  1YZ5 A;  2C1N A;  4D8M A;  1QJA A;  5J31 A;  3LW1 A;  4QX0 A;  3EB7 A;  5HF3 A;  3CQC A;  1JI6 A;  5LVZ A;  5LHO A;  4DHU A;  3SMO A;  3SMM A;  4GNT A;  4E2E A;  4DHO A;  4N7G A;  1IB1 A;  3RDH A;  3T0M A;  5D3F A;  3SMN A;  1CIY A;  1A38 A;  2NPM A;  3UAL A;  5EXA A;  4DHT A;  3O8I A;  1QJB A;  3EFZ A;  4DAU A;  2C9K A;  4JDD A;  2C74 A;  3IQU A;  4BG6 A;  4N84 A;  4Y5I A;  4DHM A;  4ARY A;  4DNK A;  5LU1 A;  5D3E A;  2BQ0 A;  4FL5 A;  4FR3 A;  5F74 A;  3P1P A;  4IHL A;  3NKX A;  4DHN A;  3T0L A;  2O8P A;  3SPR A;  3P1Q A;  1S2X A;  5D2D A;  3M50 A;  4N7Y A;  4F7R A;  1O9D A;  4WRQ A;  3IQJ A;  5EWZ A;  1A4O A;  4DAT A;  4IEA A;  2BR9 A;  3ZHE B;  4QX1 A;  5IQP A;  2BTP A;  1A37 A;  4ARX A;  3P1R A;  3IQV A;  4DHQ A;  4MOA A;  3M51 A;  5BY9 A;  4HKC A;  2O98 A;  1DLC A;  1I5P A;  3AXY C;  2WH0 A;  3CQG A;  3SP5 A;  4QX3 A;  3U9X A;  4W8J A;  2V7D A;  4ZDR A;  2B05 A;  3P1N A;  2C63 A;  2C1J A;  4DHR A;  5LU2 A;  1W99 A;  4JC3 A;  3SMK A;  2C23 A;  1O9E A;  4QX2 A;  3UZD A;  4QLI A;  3P1S A;  3P1O A;  4ZQ0 A;  3UBW A;  5BTV A;  3I4R A;  4Y3B A;  3X0U A;  3MHR A;  4Y32 A;  3E6Y A; 
#chains in the Genus database with same CATH homology
 4J6S A;  5LX2 A;  4DHP A;  2O02 A;  4FJ3 A;  1O9C A;  4DX0 A;  1O9F A;  3SML A;  4DHS A;  1YWT A;  3UX0 A;  4O46 A;  3CU8 A;  2C1N A;  1YZ5 A;  1QJA A;  5J31 A;  3LW1 A;  5HF3 A;  5LVZ A;  5LHO A;  4DHU A;  3SMO A;  3SMM A;  4GNT A;  4E2E A;  4DHO A;  4N7G A;  1IB1 A;  3RDH A;  3T0M A;  5D3F A;  3SMN A;  1A38 A;  2NPM A;  3UAL A;  5EXA A;  4DHT A;  3O8I A;  1QJB A;  3EFZ A;  4DAU A;  4JDD A;  2C74 A;  3IQU A;  4BG6 A;  4N84 A;  4Y5I A;  4DHM A;  4DNK A;  5LU1 A;  5D3E A;  2BQ0 A;  4FL5 A;  4FR3 A;  5F74 A;  3P1P A;  4IHL A;  3NKX A;  4DHN A;  3T0L A;  2O8P A;  3SPR A;  3P1Q A;  5D2D A;  3M50 A;  4N7Y A;  4F7R A;  1O9D A;  4WRQ A;  3IQJ A;  5EWZ A;  1A4O A;  4DAT A;  4IEA A;  2BR9 A;  5IQP A;  2BTP A;  1A37 A;  3P1R A;  3IQV A;  4DHQ A;  3M51 A;  5BY9 A;  4HKC A;  2O98 A;  3AXY C;  2WH0 A;  3SP5 A;  3U9X A;  2V7D A;  4ZDR A;  2B05 A;  3P1N A;  2C63 A;  2C1J A;  4DHR A;  5LU2 A;  4JC3 A;  3SMK A;  2C23 A;  1O9E A;  3UZD A;  4QLI A;  3P1S A;  3P1O A;  4ZQ0 A;  3UBW A;  5BTV A;  4Y3B A;  3MHR A;  4Y32 A;  3E6Y A; 
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similar chains in the Genus database (?% sequence similarity)
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