2O3CA

Crystal structure of zebrafish ape
Total Genus 93
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
93
sequence length
276
structure length
276
Chain Sequence
PILYEDPPEKLTSKDGRAANMKITSWNVDGLRAWVKKNGLDWVRKEDPDILCLQETKCAEKALPADITAMPEYPHKYWAGSEDKEGYSGVAMLCKTEPLNVTYGIGKEEHDKEGRVITAEFPDFFLVTAYVPNASRGLVRLDYRKTWDVDFRAYLCGLDARKPLVLCGDLNVAHQEIDLKNPKGNRKNAGFTPEEREGFTQLLEAGFTDSFRELYPDQAYAYTFWTYMMNARSKNVGWRLDYFVLSSALLPGLCDSKIRNTAMGSDHCPITLFLAV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease
pubmed doi rcsb
molecule tags Dna binding protein
source organism Danio rerio
molecule keywords APEX nuclease 1
total genus 93
structure length 276
sequence length 276
chains with identical sequence B, C
ec nomenclature ec 4.2.99.18: DNA-(apurinic or apyrimidinic site) lyase.
pdb deposition date 2006-12-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 2o3cA00
3G3YA 1BIXA 4C1RA 4B5FA 5J3PA 5J8NA 4B5GA 4F1HA 5HT2A 3I48A 2O3HA 3N9VA 4LNDA 5INPA 4QHDA 5INQA 5DFIA 1Y21A 2A41B 2V0SA 2VOAA 3W2YA 3MTCA 5DFFA 2O3CA 3NGQA 4L1ZA 5INOA 3I5VA 2IMQX 5A7IA 4CMNA 4IEMA 1ZWXA 1SR4B 3G1KA 5DV2A 1I9ZA 4JG3A 1HD7A 2JC5A 3L1WA 1DNKA 3G0AA 2JC4A 1E9NA 4AWNA 3G0RA 3G2CA 4GEWA 3DNIA 3CJCD 2F1NA 2UYRX 2A40B 4A9CA 2F2FB 5A7JA 3NGOA 3MPRA 5INNA 1DE9A 5J42A 1VYBA 3G6SA 4B5MA 5J3ZA 1YJHA 3GA6A 3I41A 2D1KB 4F1IA 2DDSA 2V0RA 4B5HA 5DFJA 3G00A 3FZIA 3I46A 5DV4A 2DDTA 3G3CA 4L1YA 4L21A 1NTFA 1WDUA 4QHEA 2EI9A 3G8VA 3NR8A 4L20A 3TEBA 2DNJA 1SI6X 1I9YA 4GZ0A 4FVAA 2DDRA 4PUQA 2J63A 1ATND 3G2DA 4FPVA 1DEWA 3G38A 5DG0A 3W2XA 2A42B 5DFHA 5J3SA 4CMLA 4B5JA 4GZ1A 5CFEA 4GZ2A 1DE8A 5INLA 5EWTA 4F1RA 4QH9A 5INMA 3W3DB 4RUWA 3G91A 3NGNA 3U8UA 2XSWA 1AKOA 4GYZA 5CFGA 5INKA 4F1HB 3K55A 4K6LF 3G4TA 4B5IA 2A3ZB 3WCXA 2ISIA
chains in the Genus database with same CATH superfamily
3G3YA 1BIXA 4C1RA 4B5FA 5J3PA 5J8NA 4B5GA 4F1HA 5HT2A 3I48A 2O3HA 3N9VA 4LNDA 5INPA 4QHDA 5INQA 5DFIA 1Y21A 2A41B 2V0SA 2VOAA 3W2YA 3MTCA 5DFFA 2O3CA 3NGQA 4L1ZA 5INOA 3I5VA 2IMQX 5A7IA 4CMNA 4IEMA 1ZWXA 1SR4B 3G1KA 5DV2A 1I9ZA 4JG3A 1HD7A 2JC5A 3L1WA 1DNKA 3G0AA 2JC4A 1E9NA 4AWNA 3G0RA 3G2CA 4GEWA 3DNIA 3CJCD 2F1NA 2UYRX 2A40B 4A9CA 2F2FB 5A7JA 3NGOA 3MPRA 5INNA 1DE9A 5J42A 1VYBA 3G6SA 4B5MA 5J3ZA 1YJHA 3GA6A 3I41A 2D1KB 4F1IA 2DDSA 2V0RA 4B5HA 5DFJA 3G00A 3FZIA 3I46A 5DV4A 2DDTA 3G3CA 4L1YA 4L21A 1NTFA 1WDUA 4QHEA 2EI9A 3G8VA 3NR8A 4L20A 3TEBA 2DNJA 1SI6X 1I9YA 4GZ0A 4FVAA 2DDRA 4PUQA 2J63A 1ATND 3G2DA 4FPVA 1DEWA 3G38A 5DG0A 3W2XA 2A42B 5DFHA 5J3SA 4CMLA 4B5JA 4GZ1A 5CFEA 4GZ2A 1DE8A 5INLA 5EWTA 4F1RA 4QH9A 5INMA 3W3DB 4RUWA 3G91A 3NGNA 3U8UA 2XSWA 1AKOA 4GYZA 5CFGA 5INKA 4F1HB 3K55A 4K6LF 3G4TA 4B5IA 2A3ZB 3WCXA 2ISIA
chains in the Genus database with same CATH topology
3G3YA 1BIXA 4C1RA 4B5FA 5J3PA 5J8NA 4B5GA 4F1HA 5HT2A 3I48A 2O3HA 3N9VA 4LNDA 5INPA 4QHDA 5INQA 5DFIA 1Y21A 2A41B 2V0SA 2VOAA 3W2YA 3MTCA 5DFFA 2O3CA 3NGQA 4L1ZA 5INOA 3I5VA 2IMQX 5A7IA 4CMNA 4IEMA 1ZWXA 1SR4B 3G1KA 5DV2A 1I9ZA 4JG3A 1HD7A 2JC5A 3L1WA 1DNKA 3G0AA 2JC4A 1E9NA 4AWNA 3G0RA 3G2CA 4GEWA 3DNIA 3CJCD 2F1NA 2UYRX 2A40B 4A9CA 2F2FB 5A7JA 3NGOA 3MPRA 5INNA 1DE9A 5J42A 1VYBA 3G6SA 4B5MA 5J3ZA 1YJHA 3GA6A 3I41A 2D1KB 4F1IA 2DDSA 2V0RA 4B5HA 5DFJA 3G00A 3FZIA 3I46A 5DV4A 2DDTA 3G3CA 4L1YA 4L21A 1NTFA 1WDUA 4QHEA 2EI9A 3G8VA 3NR8A 4L20A 3TEBA 2DNJA 1SI6X 1I9YA 4GZ0A 4FVAA 2DDRA 4PUQA 2J63A 1ATND 3G2DA 4FPVA 1DEWA 3G38A 5DG0A 3W2XA 2A42B 5DFHA 5J3SA 4CMLA 4B5JA 4GZ1A 5CFEA 4GZ2A 1DE8A 5INLA 5EWTA 4F1RA 4QH9A 5INMA 3W3DB 4RUWA 3G91A 3NGNA 3U8UA 2XSWA 1AKOA 4GYZA 5CFGA 5INKA 4F1HB 3K55A 4K6LF 3G4TA 4B5IA 2A3ZB 3WCXA 2ISIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3G3Y A;  1BIX A;  4C1R A;  4B5F A;  5J3P A;  5J8N A;  4B5G A;  4F1H A;  5HT2 A;  3I48 A;  2O3H A;  3N9V A;  4LND A;  5INP A;  4QHD A;  5INQ A;  5DFI A;  1Y21 A;  2A41 B;  2V0S A;  2VOA A;  3W2Y A;  3MTC A;  5DFF A;  2O3C A;  3NGQ A;  4L1Z A;  5INO A;  3I5V A;  2IMQ X;  5A7I A;  4CMN A;  4IEM A;  1ZWX A;  1SR4 B;  3G1K A;  5DV2 A;  1I9Z A;  4JG3 A;  1HD7 A;  2JC5 A;  3L1W A;  1DNK A;  3G0A A;  2JC4 A;  1E9N A;  4AWN A;  3G0R A;  3G2C A;  4GEW A;  3DNI A;  3CJC D;  2F1N A;  2UYR X;  2A40 B;  4A9C A;  2F2F B;  5A7J A;  3NGO A;  3MPR A;  5INN A;  1DE9 A;  5J42 A;  1VYB A;  3G6S A;  4B5M A;  5J3Z A;  1YJH A;  3GA6 A;  3I41 A;  2D1K B;  4F1I A;  2DDS A;  2V0R A;  4B5H A;  5DFJ A;  3G00 A;  3FZI A;  3I46 A;  5DV4 A;  2DDT A;  3G3C A;  4L1Y A;  4L21 A;  1NTF A;  1WDU A;  4QHE A;  2EI9 A;  3G8V A;  3NR8 A;  4L20 A;  3TEB A;  2DNJ A;  1SI6 X;  1I9Y A;  4GZ0 A;  4FVA A;  2DDR A;  4PUQ A;  2J63 A;  1ATN D;  3G2D A;  4FPV A;  1DEW A;  3G38 A;  5DG0 A;  3W2X A;  2A42 B;  5DFH A;  5J3S A;  4CML A;  4B5J A;  4GZ1 A;  5CFE A;  4GZ2 A;  1DE8 A;  5INL A;  5EWT A;  4F1R A;  4QH9 A;  5INM A;  3W3D B;  4RUW A;  3G91 A;  3NGN A;  3U8U A;  2XSW A;  1AKO A;  4GYZ A;  5CFG A;  5INK A;  4F1H B;  3K55 A;  4K6L F;  3G4T A;  4B5I A;  2A3Z B;  3WCX A;  2ISI A; 
#chains in the Genus database with same CATH topology
 3G3Y A;  1BIX A;  4C1R A;  4B5F A;  5J3P A;  5J8N A;  4B5G A;  4F1H A;  5HT2 A;  3I48 A;  2O3H A;  3N9V A;  4LND A;  5INP A;  4QHD A;  5INQ A;  5DFI A;  1Y21 A;  2A41 B;  2V0S A;  2VOA A;  3W2Y A;  3MTC A;  5DFF A;  2O3C A;  3NGQ A;  4L1Z A;  5INO A;  3I5V A;  2IMQ X;  5A7I A;  4CMN A;  4IEM A;  1ZWX A;  1SR4 B;  3G1K A;  5DV2 A;  1I9Z A;  4JG3 A;  1HD7 A;  2JC5 A;  3L1W A;  1DNK A;  3G0A A;  2JC4 A;  1E9N A;  4AWN A;  3G0R A;  3G2C A;  4GEW A;  3DNI A;  3CJC D;  2F1N A;  2UYR X;  2A40 B;  4A9C A;  2F2F B;  5A7J A;  3NGO A;  3MPR A;  5INN A;  1DE9 A;  5J42 A;  1VYB A;  3G6S A;  4B5M A;  5J3Z A;  1YJH A;  3GA6 A;  3I41 A;  2D1K B;  4F1I A;  2DDS A;  2V0R A;  4B5H A;  5DFJ A;  3G00 A;  3FZI A;  3I46 A;  5DV4 A;  2DDT A;  3G3C A;  4L1Y A;  4L21 A;  1NTF A;  1WDU A;  4QHE A;  2EI9 A;  3G8V A;  3NR8 A;  4L20 A;  3TEB A;  2DNJ A;  1SI6 X;  1I9Y A;  4GZ0 A;  4FVA A;  2DDR A;  4PUQ A;  2J63 A;  1ATN D;  3G2D A;  4FPV A;  1DEW A;  3G38 A;  5DG0 A;  3W2X A;  2A42 B;  5DFH A;  5J3S A;  4CML A;  4B5J A;  4GZ1 A;  5CFE A;  4GZ2 A;  1DE8 A;  5INL A;  5EWT A;  4F1R A;  4QH9 A;  5INM A;  3W3D B;  4RUW A;  3G91 A;  3NGN A;  3U8U A;  2XSW A;  1AKO A;  4GYZ A;  5CFG A;  5INK A;  4F1H B;  3K55 A;  4K6L F;  3G4T A;  4B5I A;  2A3Z B;  3WCX A;  2ISI A; 
#chains in the Genus database with same CATH homology
 3G3Y A;  1BIX A;  4C1R A;  4B5F A;  5J3P A;  5J8N A;  4B5G A;  4F1H A;  5HT2 A;  3I48 A;  2O3H A;  3N9V A;  4LND A;  5INP A;  4QHD A;  5INQ A;  5DFI A;  1Y21 A;  2A41 B;  2V0S A;  2VOA A;  3W2Y A;  3MTC A;  5DFF A;  2O3C A;  3NGQ A;  4L1Z A;  5INO A;  3I5V A;  2IMQ X;  5A7I A;  4CMN A;  4IEM A;  1ZWX A;  1SR4 B;  3G1K A;  5DV2 A;  1I9Z A;  4JG3 A;  1HD7 A;  2JC5 A;  3L1W A;  1DNK A;  3G0A A;  2JC4 A;  1E9N A;  4AWN A;  3G0R A;  3G2C A;  4GEW A;  3DNI A;  3CJC D;  2F1N A;  2UYR X;  2A40 B;  4A9C A;  2F2F B;  5A7J A;  3NGO A;  3MPR A;  5INN A;  1DE9 A;  5J42 A;  1VYB A;  3G6S A;  4B5M A;  5J3Z A;  1YJH A;  3GA6 A;  3I41 A;  2D1K B;  4F1I A;  2DDS A;  2V0R A;  4B5H A;  5DFJ A;  3G00 A;  3FZI A;  3I46 A;  5DV4 A;  2DDT A;  3G3C A;  4L1Y A;  4L21 A;  1NTF A;  1WDU A;  4QHE A;  2EI9 A;  3G8V A;  3NR8 A;  4L20 A;  3TEB A;  2DNJ A;  1SI6 X;  1I9Y A;  4GZ0 A;  4FVA A;  2DDR A;  4PUQ A;  2J63 A;  1ATN D;  3G2D A;  4FPV A;  1DEW A;  3G38 A;  5DG0 A;  3W2X A;  2A42 B;  5DFH A;  5J3S A;  4CML A;  4B5J A;  4GZ1 A;  5CFE A;  4GZ2 A;  1DE8 A;  5INL A;  5EWT A;  4F1R A;  4QH9 A;  5INM A;  3W3D B;  4RUW A;  3G91 A;  3NGN A;  3U8U A;  2XSW A;  1AKO A;  4GYZ A;  5CFG A;  5INK A;  4F1H B;  3K55 A;  4K6L F;  3G4T A;  4B5I A;  2A3Z B;  3WCX A;  2ISI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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