2O5JD

Crystal structure of the t. thermophilus rnap polymerase elongation complex with the ntp substrate analog
Total Genus 275
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
275
sequence length
1504
structure length
1264
Chain Sequence
KKEVRKVRIALASPEKIRSWSYGEVEKPETINYRTLKPERDGLFDERIFGPIKDYECACGKYKRQRFEGKVCERCGVEVTKSIVRRYRMGHIELATPAAHIWFVKDVPSKIGTLLDLSATELEQVLYFSKYIVLDPKGAILNGVPVEKRQLLTDEEYRELRYGKQETYPLPPGVDALVKDGEEVVKGQELAPGVVSRLDGVALYRFASILVVKARVYPFEDDVEVSTGDRVAPGDVLADGGKVKSDVYGRVEVDLVRNVVRVVESYDIDARMGAEAIQQLLKELDLEALEKELLEEMKHPSRARRAKARKRLEVVRAFLDSGNRPEWMILEAVPVLPPDLRPMVQVDGGRFATSDLNDLYRRLINRNNRLKKLLAQGAPEIIIRNEKRMLQEAVDALLDNGRRGAPVTNPGSDRPLRSLTDILSGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKRMALELFKPFLLKKMEEKGIAPNVKAARRMLERQRDIKDEVWDALEEVIHGKVVLLNRAPTLHRLGIQAFQPVLVEGQSIQLHPLVCEAFNADFDGDQMAVHVPLSSFAQAEARIQMLSAHNLLSPASGEPLAKPSRDIILGLYYITQVRKEKKGAGLEFATPEEALAAHERGEVALNAPIKVAGRETSVGRLKYVFANPDEALLAVAHGIVDLQDVVTVRYMGKRLETSPGRILFARIVAEAVEDEKVAWELIQLDVPQEKNSLKDLVYQAFLRLGMEKTARLLDALKYYGFTFSTTSGITIGIDDAVIPEEKKQYLEEADRKLLQIEQAYEMGFLTDRERYDQILQLWTETTEKVTQAVFKNFEENYPFNPLYVMAQSGARGNPQQIRQLCGLRGLMQKPSGETFEVPVRSSFREGLTVLEYFISSHGARKGGADTALRTADSGYLTRKLVDVTHEIVVREADCGTTNYISVPLFQPDEVTRSLRLRKRADIEAGLYGRVLAREVEVLGVRLEEGRYLSMDDVHLLIKAAEAGEIQEVPVRSPLTCQTRYGVCQKCYGYDLSMARPVSIGEAVGIVAAQSIGEPGTQLTMRTFHTGGVAGAADITQGLPRVIELFEARRPKAKAIDPHQLLEAKGPEAVERYLVEEIQKVYRAQGVKLHDKHIEIVVRQMMKYVEVTDPGDSRLLEGQVLEKWDVEALNERLIAEGKTPVAWKPLLMGVTKSALSTKSWLSAASFQNTTHVLTEAAIAGKKDELIGLKENVILGRLIPAGTGSDFVRFTQVVDQKTLKAIEEARKEAVEA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for substrate loading in bacterial RNA polymerase.
pubmed doi rcsb
molecule tags Transferase/dna-rna hybrid
molecule keywords 5'-D(P*CP*CP*CP*TP*GP*TP*CP*TP*GP*GP*CP*GP*TP*TP*CP*GP*CP*GP
total genus 275
structure length 1264
sequence length 1504
chains with identical sequence N
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2006-12-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00623 RNA_pol_Rpb1_2 RNA polymerase Rpb1, domain 2
D PF04983 RNA_pol_Rpb1_3 RNA polymerase Rpb1, domain 3
D PF04997 RNA_pol_Rpb1_1 RNA polymerase Rpb1, domain 1
D PF04998 RNA_pol_Rpb1_5 RNA polymerase Rpb1, domain 5
D PF05000 RNA_pol_Rpb1_4 RNA polymerase Rpb1, domain 4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.132.30 Mainly Alpha Orthogonal Bundle Topoisomerase I; Chain A, domain 4 Topoisomerase I; Chain A, domain 4 2o5jD05
1.10.274.100 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 Enzyme I; Chain A, domain 2 2o5jD04
2.20.28.170 Mainly Beta Single Sheet Rubrerythrin, domain 2 Rubrerythrin, domain 2 2o5jD07
2.40.40.70 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 2o5jD03
1I3QA 2Y0SA 1ZYRD 2A68D 2NVYA 2PMZA 2E2IA 1WCMA 1K83A 3GTLA 1TWFA 3GTGA 1Y1VA 1TWGA 2WB1A 2NVXA 2A6ED 4AYBA 2E2HA 2JA5A 3GTOA 3GTKA 1I6VD 1TWCA 1YNND 1I50A 2BE5D 1TWHA 3HKZA 2CW0D 3GTJA 2YU9A 2A69D 3CQZA 2A6HD 2VUMA 4QIWA 2JA7A 2R92A 1IW7D 3GTPA 1Y1WA 2JA6A 1YNJD 1SFOA 3GTMA 1HQMD 2B63A 4C2MA 1SMYD 1TWAA 2R93A 3FKIA 2WAQA 3GTQA 3H0GA 1R9TA 2O5JD 2R7ZA
chains in the Genus database with same CATH superfamily
3S17L 4A3KL 1L8FA 4KDLA 2E2IL 3GTLA 1WJVA 1ZRPA 5JSNB 5MGNA 4GFQA 2FIOA 1DD5A 4E6YA 3RZTA 4A3CL 4BY7L 1ISEA 5RXNA 2RDVA 4RXNA 3IR7A 1E5VA 1KQGA 4AI2A 1Z92B 5AI3A 2Y0NA 5K2ME 4JJOA 4WFN1 4KDDA 1H7VA 3X2GA 4EJ3A 1LTLA 3QQ8A 3H0GA 3LR8A 4L8IA 5M5YL 2JA7L 1LKOA 3X2PA 4L48A 3H9CA 2E2HL 5GLFA 2NVYL 1Y4ZA 4AHWA 2LTHA 4OYDB 4Y52L 3M3YL 2AE0X 2XJPA 3IR6A 1OWBA 2WAQP 5FLML 2YU9A 2A69D 4C6GA 1R7RA 2LPJA 2J9UB 1Y698 3OUGA 4LHNA 2PJJA 2V0EA 4FG2A 5FTNA 2LKMB 3LWPB 4AOKB 4AAYA 2NAPA 1SMYD 2CR8A 3PWFA 1CAAA 3ZG6A 3HAXC 5IYDL 4FERA 1B2OA 2PNWA 2M4VA 4D7ZB 2HR5A 3GTPL 2LYIA 1PFVA 4JP7A 4KLNA 2GMGA 2NVYA 1V9MA 1NNQA 3JR7A 2E2IA 3O5AA 1B2JA 4FG4A 1T6JA 1Y1VA 1WQGA 3NZ4A 3GTQL 5M5XL 3GTJL 1SEUA 3M4OL 1PPYA 3I4ML 3H97A 3LHPS 1Y1WA 1FHMA 3J7Z1 1PQFA 2MQAA 1W27A 1EU1A 2V0FA 1VC3B 3X2NA 3K7AL 1DX8A 1Q8IA 1B13A 1EJ9A 3HOVL 4AZDA 3FKIA 4JAEA 1K4SA 3EZBA 1TMOA 3LR6A 3HKZP 3HU3A 1E8JA 3X2JA 4GA6A 1IRNA 2JI3A 2K3NA 4KODA 1QCVA 2ERSA 1CZ5A 2XJRA 4C3IL 3HU1A 4AHXA 5IYBL 4KAWX 3QVDA 4JADA 1PT1A 3GTOA 4A3DL 1I50A 1HD5A 3GTJA 4GA5A 1PFWA 1QYBA 3KYLA 3LNLA 2XJQA 1SFOL 1YNJD 2G5DA 2CKCA 4Q5GA 1TWAA 2R93A 2Z3QB 3PO3L 2WAQA 3S15L 1TWCL 1S30A 2MS3A 1OGYA 2R7ZA 2AQLA 3VPBE 4V2RA 3IR5A 1R49A 5IZ2A 2M6OA 1PT0A 3PIO1 2JIQA 4A3GL 2VPZA 3J7Y1 3MQKB 1VCXA 7RXNA 5C3EL 3HOWL 4NOHA 2AUSB 4FFTA 1ODHA 4FYDA 2VL6A 1H5NA 2KQAA 1SMUA 2JIRA 4CEHA 3MAQA 2NVXL 4ZN1B 4LMOA 2LCQA 5IYCL 1G8JA 1ZYMA 2EEOB 4F3EA 1GE9A 3S1ML 2KI8A 1JYBA 2VUMA 3PKIA 3K35A 1R0FA 1WCML 2VPWA 3PZAA 4A3FL 2Z3RB 3HOUL 1VZHA 2Y0SP 1WQHA 2BH0A 5C4JL 3GTGA 3KYYA 4CRYG 1SMWA 1OA9A 2QL0A 1TWGL 3WVOA 1F4LA 2M6PA 4G6BA 5CQGA 5MF6A 2C45A 1B71A 1TWHA 3B08B 3QQCE 4A3ML 4FXDA 5GADc 4JLRC 1DMRA 4Y7NL 1IU6A 2GAEA 2R92A 1IW7D 1SC7A 4C5UA 1RRJA 4KB2A 1EZBA 5M3FL 2O5JD 1YUZA 3HU2A 3KYVA 3PIP1 4BBSL 5FJ8L 1CZ4A 1NH3A 3LWRB 3HOZL 4C5SA 3S1NL 3B0AB 1KQFA 2B5ID 3LWQB 1Y1VL 3CF2A 2X0QA 3RYGA 4A3EL 1NXGA 2JI2A 2M4YA 5MFPA 4V196 1PYQA 1E18A 1YK4A 4POFA 3S14L 1E32A 2FIPA 3S2HL 3NFPI 4XXBB 3K58A 2E2JL 1R0JA 1BQ9A 2NVTL 3GTMA 5IP7L 5DYIA 5AN9H 1CR5A 1PQEA 1AW8B 3EZEA 3QWZA 1R9TL 3X2LA 1PQHA 3KYUA 2N1DB 4CEJA 2EZBA 5C4XL 4KC6A 3RZ6A 2JIPA 2XJSA 2Y0SA 3WWNB 3HJYB 3P8BA 2PSMC 5M5WL 3I4NL 4AI3A 1FDIA 1Q16A 1PZXA 1TWFA 1WC2A 1TWGA 2HCZX 2NVXA 2PJHB 4IP8A 1LKMA 1YNND 4FGUA 3H3VM 4RV0A 1RYTA 2VUML 4IP9A 6RXNA 4ZN3B 3WWLA 3GTPA 2JIOA 2JA6A 3H99A 2ERJA 1R5ZA 1NXEA 2V45A 3GTLL 1FHHA 4POGA 3RZOL 4BABA 3X2OA 3DMRA 5B6CA 1T8IA 2R7ZL 5M3ML 5GLYA 1R0HA 2PMZA 3LRDA 1UHEA 3M4AA 1A31A 4JP6A 4A3LL 2LPIA 1RB9A 2X0PA 2E2HA 2DSXA 3GTKA 4A3IL 2H12A 2VK9A 2CW0D 5C18A 2A6HD 3K59A 2ENGA 2C6BA 1SIWA 3GTML 5DYGA 4H3TA 1YUXA 1R0GA 3LWOB 1BRFA 2VPYA 2PICA 3SUKA 2NVQL 1PYUB 5EINC 4NOKA 3U4QA 2G6GA 4QIWP 1EH1A 1Y5IA 4YWLA 4KDIA 2PVXA 8RXNA 2N3EA 1H0HA 4JS7A 1A35A 2K2DA 1OA7A 2E7ZA 4A3JL 1FDOA 2NYAA 3SS2A 4AHZA 3HOXL 5H1Sc 5FTKA 1RDVA 1T9QA 2F4QA 2EZAA 4CRZA 2ZIXA 4X6AL 5T5ID 3LPEB 3KYXA 3S1QL 1T9OA 1G8KA 1RDGA 4AN8A 4GS7D 3A44A 3H0GL 2JI1A 5C44L 1R27A 3SUJA 2PYAA 2B9SB 3GTOL 5JVG1 4NOLA 4DMRA 1YLEA 2JA5L 4K9FA 5DM61 3CQZA 4C2M1 2PMZP 2PPTA 1SMMA 1AA6A 4O26A 4LHLA 4ME3A 1HQMD 4C2MA 1R0IA 1EZAA 5MLC9 1K83L 5GAHc 3LWVB 3GTGL 3GTKL 5FTLA 3K5OA 3X2KA 5C1BA 4AR5A 1Y1WL 1TGOA 2PI8A 1LPQA 1I3QA 4ENGA 3X2HA 2A68D 5EIOC 2R92L 1YK5A 2XJTA 2A6ED 1QCSA 2JA5A 2KKDA 3PL5A 1T6PA 3KYWA 3HOYL 1BW4A 1WQFA 2BE5D 4JAFA 1C09A 4C3JL 4XGHA 1N10A 2JA6L 3ML1A 2YUJA 5H4UA 5IY0A 1RWDA 2HWGA 4JAGA 1I50L 4BXXL 3SUMA 5C9HA 3QQ7A 3LF9A 1YV1A 4KB4A 3QC8A 2CKAA 4ZM7A 1ZYRD 3X2MA 1VZGA 1BW3A 4AYBP 2B63L 2WB1A 1LKPA 3D30A 2VPXA 4B8CD 4CS0A 3K5LA 1TWHL 5FTMA 2MX9A 1VZIA 2NYDA 3PLXB 2JIMA 2JA7A 5T5MD 3K5NA 1PFYA 1BFYA 3S2DL 5DM71 4AR4A 3S16L 1OWCA 1ZC1A 2K3OA 1WLFA 3LR2A 5FTJA 3H9BA 3FKIL 2XJUA 1BQ8A 4C3HL 5GM9A 5JVH1 1IU5A 3X2IA 2YIIA 3K5MA 4FBSA 3TM7B 2X0OA 2AYJA 4Q5VA 1K83A 4CEIA 2F5JA 1BE7A 4BBRL 2V3BB 2L0ZA 5GLXA 1I6VD 3IAYA 1IROA 4AR6A 4A93L 3HKZA 4A3BL 1S24A 2YU9L 3SULA 2AQCA 2IV2X 3IU3I 3P9AA 2HVYC 5IP9L 3DU6A 5EPPA 2APOB 3EZAA 4AI0A 2KN9A 1MIUA 4AR3A 4UY81 2PVEA 4C5RA 4QCLA 5MLC3 2C6AA 1DMSA 1R9TA 1UHDA 4JCWA 2XJVA 3MPSA 1EK8A 1DVBA 2MX8A 4D3ZA 4AI1A 1CADA 3HJWB 1IS1A 1WCMA 3M3GA 2WB1P 1T9PA 4CQ5A 4YWMA 4AVRA 5GAGc 1TWFL 2V3VA 3CZBA 4TVMA 4AHCA 3SJRA 4QIWA 1I3QL 2MP0A 3RZDL 3PKJA 1TL8A 3S1RL 2EY4E 3K57A 2HROA 3TIWA 3U44A 5MFZA 3CQZL 5GAEc 5AI2A 4BY1L 1QQTA 4D3YA 4BAAA 2K3QA 1RYQA 4U671 4AHYA 4KO8A 1S3SA 2R4GA 1PFUA 1S2ZA 3FDJA 4AYBA 1TWAL 4V2QA 1TWCA 4NOMA 3PO2L 4TPUA 2DMRA 1RR8C 3DU5A 1E60A 1SFOA 1P7PA 1A36A 3MSUA 2B63A 4AONB 3ENGA 2EZCA 2JA8L 1Y2MA 1QDNA 5JSBB 2R93L 3GTQA 1K4TA 1I6HL 1E61A 2RFKB 3P2AA
chains in the Genus database with same CATH topology
4KDLA 3GTLA 1WJVA 1ZRPA 5JSNB 5MGNA 4GFQA 2FIOA 1DD5A 4E6YA 3RZTA 1ISEA 5RXNA 2RDVA 4RXNA 3IR7A 1E5VA 1KQGA 4AI2A 1Z92B 5AI3A 2Y0NA 5K2ME 4WFN1 4KDDA 1H7VA 4EJ3A 1LTLA 3QQ8A 3H0GA 3LR8A 4L8IA 1LKOA 5GLFA 1Y4ZA 4AHWA 2LTHA 4OYDB 2AE0X 2XJPA 3IR6A 1OWBA 2YU9A 2A69D 1R7RA 2LPJA 2J9UB 1Y698 3OUGA 4LHNA 2PJJA 2V0EA 5FTNA 2LKMB 4AOKB 4AAYA 2NAPA 3PWFA 1SMYD 2CR8A 1CAAA 3ZG6A 1B2OA 2PNWA 2M4VA 4D7ZB 2HR5A 2LYIA 4KLNA 2GMGA 2NVYA 1V9MA 1NNQA 2E2IA 3O5AA 1B2JA 1Y1VA 1WQGA 1SEUA 1PPYA 3LHPS 1Y1WA 1FHMA 3J7Z1 1PQFA 2MQAA 1EU1A 2V0FA 1VC3B 1DX8A 1Q8IA 1B13A 1EJ9A 4AZDA 3FKIA 4JAEA 1K4SA 1TMOA 3LR6A 3HU3A 1E8JA 4GA6A 1IRNA 2JI3A 2K3NA 4KODA 1QCVA 2ERSA 1CZ5A 2XJRA 3HU1A 4AHXA 4KAWX 3QVDA 4JADA 1PT1A 3GTOA 1I50A 3GTJA 4GA5A 1QYBA 3KYLA 3LNLA 2XJQA 2G5DA 1YNJD 2CKCA 4Q5GA 1TWAA 2R93A 2Z3QB 2WAQA 1S30A 2MS3A 1OGYA 2R7ZA 2AQLA 3VPBE 3IR5A 1R49A 5IZ2A 2M6OA 1PT0A 3PIO1 2JIQA 2VPZA 3J7Y1 1VCXA 7RXNA 4NOHA 1ODHA 4FYDA 2VL6A 1H5NA 1SMUA 2JIRA 4CEHA 3MAQA 4ZN1B 4LMOA 2LCQA 1G8JA 2EEOB 4F3EA 1GE9A 2KI8A 1JYBA 2VUMA 3PKIA 3K35A 1R0FA 2VPWA 3PZAA 2Z3RB 1VZHA 1WQHA 4CRYG 3GTGA 3KYYA 1SMWA 2QL0A 3WVOA 2M6PA 4G6BA 5MF6A 5CQGA 2C45A 1B71A 1TWHA 3B08B 3QQCE 4FXDA 5GADc 4JLRC 1DMRA 1IU6A 2GAEA 2R92A 1IW7D 1SC7A 1RRJA 4KB2A 2O5JD 1YUZA 3HU2A 3KYVA 3PIP1 1CZ4A 1NH3A 3B0AB 1KQFA 2B5ID 3CF2A 2X0QA 3RYGA 1NXGA 2JI2A 2M4YA 5MFPA 4V196 1PYQA 1E18A 1YK4A 4POFA 1E32A 2FIPA 3NFPI 4XXBB 3K58A 1R0JA 1BQ9A 3GTMA 5DYIA 5AN9H 1CR5A 1PQEA 1AW8B 3QWZA 1PQHA 3KYUA 2N1DB 4CEJA 4KC6A 3RZ6A 2JIPA 2XJSA 2Y0SA 3WWNB 3P8BA 2PSMC 4AI3A 1FDIA 1Q16A 1TWFA 1TWGA 2NVXA 2PJHB 4IP8A 1LKMA 1YNND 4FGUA 4RV0A 1RYTA 4IP9A 6RXNA 4ZN3B 3WWLA 3GTPA 2JIOA 2JA6A 2ERJA 1R5ZA 1NXEA 2V45A 1FHHA 4POGA 3DMRA 5B6CA 1T8IA 1R0HA 2PMZA 3LRDA 1UHEA 3M4AA 1A31A 2LPIA 1RB9A 2X0PA 2E2HA 2DSXA 3GTKA 2H12A 2VK9A 2CW0D 5C18A 2A6HD 3K59A 2C6BA 1SIWA 5DYGA 4H3TA 1YUXA 1R0GA 2VPYA 1BRFA 2PICA 1PYUB 5EINC 4NOKA 3U4QA 2G6GA 1EH1A 1Y5IA 4YWLA 4KDIA 2PVXA 8RXNA 2N3EA 1H0HA 1A35A 2K2DA 2E7ZA 1FDOA 2NYAA 3SS2A 4AHZA 5H1Sc 5FTKA 1RDVA 1T9QA 2F4QA 4CRZA 2ZIXA 5T5ID 3LPEB 3KYXA 1G8KA 1T9OA 1RDGA 4AN8A 4GS7D 3A44A 2JI1A 1R27A 2PYAA 2B9SB 5JVG1 4NOLA 4DMRA 1YLEA 4K9FA 5DM61 3CQZA 2PPTA 1SMMA 1AA6A 4O26A 4LHLA 4ME3A 1HQMD 4C2MA 1R0IA 5MLC9 5GAHc 5FTLA 3K5OA 5C1BA 4AR5A 1TGOA 2PI8A 1LPQA 1I3QA 2A68D 5EIOC 1YK5A 2XJTA 2A6ED 1QCSA 2JA5A 2KKDA 3KYWA 1WQFA 2BE5D 4JAFA 1C09A 4XGHA 3ML1A 2YUJA 5IY0A 1RWDA 4JAGA 5C9HA 3QQ7A 3LF9A 1YV1A 4KB4A 3QC8A 2CKAA 1ZYRD 1VZGA 2WB1A 1LKPA 2VPXA 4B8CD 4CS0A 3K5LA 5FTMA 2MX9A 1VZIA 2NYDA 3PLXB 2JIMA 2JA7A 5T5MD 3K5NA 1BFYA 5DM71 4AR4A 1OWCA 1ZC1A 2K3OA 1WLFA 3LR2A 5FTJA 2XJUA 1BQ8A 5JVH1 1IU5A 3K5MA 4FBSA 3TM7B 2X0OA 2AYJA 4Q5VA 1K83A 4CEIA 2F5JA 1BE7A 2V3BB 2L0ZA 1I6VD 3IAYA 1IROA 4AR6A 3HKZA 1S24A 2IV2X 3IU3I 3P9AA 3DU6A 5EPPA 4UY81 4AI0A 2KN9A 1MIUA 4AR3A 2PVEA 4QCLA 5MLC3 2C6AA 1DMSA 1R9TA 1UHDA 2XJVA 3MPSA 1EK8A 1DVBA 2MX8A 4D3ZA 4AI1A 1CADA 1IS1A 1WCMA 1T9PA 4YWMA 5GAGc 2V3VA 3CZBA 4TVMA 4AHCA 3SJRA 4QIWA 3PKJA 1TL8A 3K57A 3TIWA 3U44A 5MFZA 5GAEc 5AI2A 4D3YA 2K3QA 1RYQA 4U671 4AHYA 4KO8A 1S3SA 2R4GA 1S2ZA 4AYBA 1TWCA 4NOMA 4TPUA 2DMRA 1RR8C 3DU5A 1E60A 1SFOA 1A36A 3MSUA 2B63A 4AONB 1QDNA 5JSBB 3GTQA 1K4TA 1E61A 3P2AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1I3Q A;  2Y0S A;  1ZYR D;  2A68 D;  2NVY A;  2PMZ A;  2E2I A;  1WCM A;  1K83 A;  3GTL A;  1TWF A;  3GTG A;  1Y1V A;  1TWG A;  2WB1 A;  2NVX A;  2A6E D;  4AYB A;  2E2H A;  2JA5 A;  3GTO A;  3GTK A;  1I6V D;  1TWC A;  1YNN D;  1I50 A;  2BE5 D;  1TWH A;  3HKZ A;  2CW0 D;  3GTJ A;  2YU9 A;  2A69 D;  3CQZ A;  2A6H D;  2VUM A;  4QIW A;  2JA7 A;  2R92 A;  1IW7 D;  3GTP A;  1Y1W A;  2JA6 A;  1YNJ D;  1SFO A;  3GTM A;  1HQM D;  2B63 A;  4C2M A;  1SMY D;  1TWA A;  2R93 A;  3FKI A;  2WAQ A;  3GTQ A;  3H0G A;  1R9T A;  2O5J D;  2R7Z A; 
#chains in the Genus database with same CATH topology
 3S17 L;  4A3K L;  1L8F A;  4KDL A;  2E2I L;  3GTL A;  1WJV A;  1ZRP A;  5JSN B;  5MGN A;  4GFQ A;  2FIO A;  1DD5 A;  4E6Y A;  3RZT A;  4A3C L;  4BY7 L;  1ISE A;  5RXN A;  2RDV A;  4RXN A;  3IR7 A;  1E5V A;  1KQG A;  4AI2 A;  1Z92 B;  5AI3 A;  2Y0N A;  5K2M E;  4JJO A;  4WFN 1;  4KDD A;  1H7V A;  3X2G A;  4EJ3 A;  1LTL A;  3QQ8 A;  3H0G A;  3LR8 A;  4L8I A;  5M5Y L;  2JA7 L;  1LKO A;  3X2P A;  4L48 A;  3H9C A;  2E2H L;  5GLF A;  2NVY L;  1Y4Z A;  4AHW A;  2LTH A;  4OYD B;  4Y52 L;  3M3Y L;  2AE0 X;  2XJP A;  3IR6 A;  1OWB A;  2WAQ P;  5FLM L;  2YU9 A;  2A69 D;  4C6G A;  1R7R A;  2LPJ A;  2J9U B;  1Y69 8;  3OUG A;  4LHN A;  2PJJ A;  2V0E A;  4FG2 A;  5FTN A;  2LKM B;  3LWP B;  4AOK B;  4AAY A;  2NAP A;  1SMY D;  2CR8 A;  3PWF A;  1CAA A;  3ZG6 A;  3HAX C;  5IYD L;  4FER A;  1B2O A;  2PNW A;  2M4V A;  4D7Z B;  2HR5 A;  3GTP L;  2LYI A;  1PFV A;  4JP7 A;  4KLN A;  2GMG A;  2NVY A;  1V9M A;  1NNQ A;  3JR7 A;  2E2I A;  3O5A A;  1B2J A;  4FG4 A;  1T6J A;  1Y1V A;  1WQG A;  3NZ4 A;  3GTQ L;  5M5X L;  3GTJ L;  1SEU A;  3M4O L;  1PPY A;  3I4M L;  3H97 A;  3LHP S;  1Y1W A;  1FHM A;  3J7Z 1;  1PQF A;  2MQA A;  1W27 A;  1EU1 A;  2V0F A;  1VC3 B;  3X2N A;  3K7A L;  1DX8 A;  1Q8I A;  1B13 A;  1EJ9 A;  3HOV L;  4AZD A;  3FKI A;  4JAE A;  1K4S A;  3EZB A;  1TMO A;  3LR6 A;  3HKZ P;  3HU3 A;  1E8J A;  3X2J A;  4GA6 A;  1IRN A;  2JI3 A;  2K3N A;  4KOD A;  1QCV A;  2ERS A;  1CZ5 A;  2XJR A;  4C3I L;  3HU1 A;  4AHX A;  5IYB L;  4KAW X;  3QVD A;  4JAD A;  1PT1 A;  3GTO A;  4A3D L;  1I50 A;  1HD5 A;  3GTJ A;  4GA5 A;  1PFW A;  1QYB A;  3KYL A;  3LNL A;  2XJQ A;  1SFO L;  1YNJ D;  2G5D A;  2CKC A;  4Q5G A;  1TWA A;  2R93 A;  2Z3Q B;  3PO3 L;  2WAQ A;  3S15 L;  1TWC L;  1S30 A;  2MS3 A;  1OGY A;  2R7Z A;  2AQL A;  3VPB E;  4V2R A;  3IR5 A;  1R49 A;  5IZ2 A;  2M6O A;  1PT0 A;  3PIO 1;  2JIQ A;  4A3G L;  2VPZ A;  3J7Y 1;  3MQK B;  1VCX A;  7RXN A;  5C3E L;  3HOW L;  4NOH A;  2AUS B;  4FFT A;  1ODH A;  4FYD A;  2VL6 A;  1H5N A;  2KQA A;  1SMU A;  2JIR A;  4CEH A;  3MAQ A;  2NVX L;  4ZN1 B;  4LMO A;  2LCQ A;  5IYC L;  1G8J A;  1ZYM A;  2EEO B;  4F3E A;  1GE9 A;  3S1M L;  2KI8 A;  1JYB A;  2VUM A;  3PKI A;  3K35 A;  1R0F A;  1WCM L;  2VPW A;  3PZA A;  4A3F L;  2Z3R B;  3HOU L;  1VZH A;  2Y0S P;  1WQH A;  2BH0 A;  5C4J L;  3GTG A;  3KYY A;  4CRY G;  1SMW A;  1OA9 A;  2QL0 A;  1TWG L;  3WVO A;  1F4L A;  2M6P A;  4G6B A;  5CQG A;  5MF6 A;  2C45 A;  1B71 A;  1TWH A;  3B08 B;  3QQC E;  4A3M L;  4FXD A;  5GAD c;  4JLR C;  1DMR A;  4Y7N L;  1IU6 A;  2GAE A;  2R92 A;  1IW7 D;  1SC7 A;  4C5U A;  1RRJ A;  4KB2 A;  1EZB A;  5M3F L;  2O5J D;  1YUZ A;  3HU2 A;  3KYV A;  3PIP 1;  4BBS L;  5FJ8 L;  1CZ4 A;  1NH3 A;  3LWR B;  3HOZ L;  4C5S A;  3S1N L;  3B0A B;  1KQF A;  2B5I D;  3LWQ B;  1Y1V L;  3CF2 A;  2X0Q A;  3RYG A;  4A3E L;  1NXG A;  2JI2 A;  2M4Y A;  5MFP A;  4V19 6;  1PYQ A;  1E18 A;  1YK4 A;  4POF A;  3S14 L;  1E32 A;  2FIP A;  3S2H L;  3NFP I;  4XXB B;  3K58 A;  2E2J L;  1R0J A;  1BQ9 A;  2NVT L;  3GTM A;  5IP7 L;  5DYI A;  5AN9 H;  1CR5 A;  1PQE A;  1AW8 B;  3EZE A;  3QWZ A;  1R9T L;  3X2L A;  1PQH A;  3KYU A;  2N1D B;  4CEJ A;  2EZB A;  5C4X L;  4KC6 A;  3RZ6 A;  2JIP A;  2XJS A;  2Y0S A;  3WWN B;  3HJY B;  3P8B A;  2PSM C;  5M5W L;  3I4N L;  4AI3 A;  1FDI A;  1Q16 A;  1PZX A;  1TWF A;  1WC2 A;  1TWG A;  2HCZ X;  2NVX A;  2PJH B;  4IP8 A;  1LKM A;  1YNN D;  4FGU A;  3H3V M;  4RV0 A;  1RYT A;  2VUM L;  4IP9 A;  6RXN A;  4ZN3 B;  3WWL A;  3GTP A;  2JIO A;  2JA6 A;  3H99 A;  2ERJ A;  1R5Z A;  1NXE A;  2V45 A;  3GTL L;  1FHH A;  4POG A;  3RZO L;  4BAB A;  3X2O A;  3DMR A;  5B6C A;  1T8I A;  2R7Z L;  5M3M L;  5GLY A;  1R0H A;  2PMZ A;  3LRD A;  1UHE A;  3M4A A;  1A31 A;  4JP6 A;  4A3L L;  2LPI A;  1RB9 A;  2X0P A;  2E2H A;  2DSX A;  3GTK A;  4A3I L;  2H12 A;  2VK9 A;  2CW0 D;  5C18 A;  2A6H D;  3K59 A;  2ENG A;  2C6B A;  1SIW A;  3GTM L;  5DYG A;  4H3T A;  1YUX A;  1R0G A;  3LWO B;  1BRF A;  2VPY A;  2PIC A;  3SUK A;  2NVQ L;  1PYU B;  5EIN C;  4NOK A;  3U4Q A;  2G6G A;  4QIW P;  1EH1 A;  1Y5I A;  4YWL A;  4KDI A;  2PVX A;  8RXN A;  2N3E A;  1H0H A;  4JS7 A;  1A35 A;  2K2D A;  1OA7 A;  2E7Z A;  4A3J L;  1FDO A;  2NYA A;  3SS2 A;  4AHZ A;  3HOX L;  5H1S c;  5FTK A;  1RDV A;  1T9Q A;  2F4Q A;  2EZA A;  4CRZ A;  2ZIX A;  4X6A L;  5T5I D;  3LPE B;  3KYX A;  3S1Q L;  1T9O A;  1G8K A;  1RDG A;  4AN8 A;  4GS7 D;  3A44 A;  3H0G L;  2JI1 A;  5C44 L;  1R27 A;  3SUJ A;  2PYA A;  2B9S B;  3GTO L;  5JVG 1;  4NOL A;  4DMR A;  1YLE A;  2JA5 L;  4K9F A;  5DM6 1;  3CQZ A;  4C2M 1;  2PMZ P;  2PPT A;  1SMM A;  1AA6 A;  4O26 A;  4LHL A;  4ME3 A;  1HQM D;  4C2M A;  1R0I A;  1EZA A;  5MLC 9;  1K83 L;  5GAH c;  3LWV B;  3GTG L;  3GTK L;  5FTL A;  3K5O A;  3X2K A;  5C1B A;  4AR5 A;  1Y1W L;  1TGO A;  2PI8 A;  1LPQ A;  1I3Q A;  4ENG A;  3X2H A;  2A68 D;  5EIO C;  2R92 L;  1YK5 A;  2XJT A;  2A6E D;  1QCS A;  2JA5 A;  2KKD A;  3PL5 A;  1T6P A;  3KYW A;  3HOY L;  1BW4 A;  1WQF A;  2BE5 D;  4JAF A;  1C09 A;  4C3J L;  4XGH A;  1N10 A;  2JA6 L;  3ML1 A;  2YUJ A;  5H4U A;  5IY0 A;  1RWD A;  2HWG A;  4JAG A;  1I50 L;  4BXX L;  3SUM A;  5C9H A;  3QQ7 A;  3LF9 A;  1YV1 A;  4KB4 A;  3QC8 A;  2CKA A;  4ZM7 A;  1ZYR D;  3X2M A;  1VZG A;  1BW3 A;  4AYB P;  2B63 L;  2WB1 A;  1LKP A;  3D30 A;  2VPX A;  4B8C D;  4CS0 A;  3K5L A;  1TWH L;  5FTM A;  2MX9 A;  1VZI A;  2NYD A;  3PLX B;  2JIM A;  2JA7 A;  5T5M D;  3K5N A;  1PFY A;  1BFY A;  3S2D L;  5DM7 1;  4AR4 A;  3S16 L;  1OWC A;  1ZC1 A;  2K3O A;  1WLF A;  3LR2 A;  5FTJ A;  3H9B A;  3FKI L;  2XJU A;  1BQ8 A;  4C3H L;  5GM9 A;  5JVH 1;  1IU5 A;  3X2I A;  2YII A;  3K5M A;  4FBS A;  3TM7 B;  2X0O A;  2AYJ A;  4Q5V A;  1K83 A;  4CEI A;  2F5J A;  1BE7 A;  4BBR L;  2V3B B;  2L0Z A;  5GLX A;  1I6V D;  3IAY A;  1IRO A;  4AR6 A;  4A93 L;  3HKZ A;  4A3B L;  1S24 A;  2YU9 L;  3SUL A;  2AQC A;  2IV2 X;  3IU3 I;  3P9A A;  2HVY C;  5IP9 L;  3DU6 A;  5EPP A;  2APO B;  3EZA A;  4AI0 A;  2KN9 A;  1MIU A;  4AR3 A;  4UY8 1;  2PVE A;  4C5R A;  4QCL A;  5MLC 3;  2C6A A;  1DMS A;  1R9T A;  1UHD A;  4JCW A;  2XJV A;  3MPS A;  1EK8 A;  1DVB A;  2MX8 A;  4D3Z A;  4AI1 A;  1CAD A;  3HJW B;  1IS1 A;  1WCM A;  3M3G A;  2WB1 P;  1T9P A;  4CQ5 A;  4YWM A;  4AVR A;  5GAG c;  1TWF L;  2V3V A;  3CZB A;  4TVM A;  4AHC A;  3SJR A;  4QIW A;  1I3Q L;  2MP0 A;  3RZD L;  3PKJ A;  1TL8 A;  3S1R L;  2EY4 E;  3K57 A;  2HRO A;  3TIW A;  3U44 A;  5MFZ A;  3CQZ L;  5GAE c;  5AI2 A;  4BY1 L;  1QQT A;  4D3Y A;  4BAA A;  2K3Q A;  1RYQ A;  4U67 1;  4AHY A;  4KO8 A;  1S3S A;  2R4G A;  1PFU A;  1S2Z A;  3FDJ A;  4AYB A;  1TWA L;  4V2Q A;  1TWC A;  4NOM A;  3PO2 L;  4TPU A;  2DMR A;  1RR8 C;  3DU5 A;  1E60 A;  1SFO A;  1P7P A;  1A36 A;  3MSU A;  2B63 A;  4AON B;  3ENG A;  2EZC A;  2JA8 L;  1Y2M A;  1QDN A;  5JSB B;  2R93 L;  3GTQ A;  1K4T A;  1I6H L;  1E61 A;  2RFK B;  3P2A A; 
#chains in the Genus database with same CATH homology
 4KDL A;  3GTL A;  1WJV A;  1ZRP A;  5JSN B;  5MGN A;  4GFQ A;  2FIO A;  1DD5 A;  4E6Y A;  3RZT A;  1ISE A;  5RXN A;  2RDV A;  4RXN A;  3IR7 A;  1E5V A;  1KQG A;  4AI2 A;  1Z92 B;  5AI3 A;  2Y0N A;  5K2M E;  4WFN 1;  4KDD A;  1H7V A;  4EJ3 A;  1LTL A;  3QQ8 A;  3H0G A;  3LR8 A;  4L8I A;  1LKO A;  5GLF A;  1Y4Z A;  4AHW A;  2LTH A;  4OYD B;  2AE0 X;  2XJP A;  3IR6 A;  1OWB A;  2YU9 A;  2A69 D;  1R7R A;  2LPJ A;  2J9U B;  1Y69 8;  3OUG A;  4LHN A;  2PJJ A;  2V0E A;  5FTN A;  2LKM B;  4AOK B;  4AAY A;  2NAP A;  3PWF A;  1SMY D;  2CR8 A;  1CAA A;  3ZG6 A;  1B2O A;  2PNW A;  2M4V A;  4D7Z B;  2HR5 A;  2LYI A;  4KLN A;  2GMG A;  2NVY A;  1V9M A;  1NNQ A;  2E2I A;  3O5A A;  1B2J A;  1Y1V A;  1WQG A;  1SEU A;  1PPY A;  3LHP S;  1Y1W A;  1FHM A;  3J7Z 1;  1PQF A;  2MQA A;  1EU1 A;  2V0F A;  1VC3 B;  1DX8 A;  1Q8I A;  1B13 A;  1EJ9 A;  4AZD A;  3FKI A;  4JAE A;  1K4S A;  1TMO A;  3LR6 A;  3HU3 A;  1E8J A;  4GA6 A;  1IRN A;  2JI3 A;  2K3N A;  4KOD A;  1QCV A;  2ERS A;  1CZ5 A;  2XJR A;  3HU1 A;  4AHX A;  4KAW X;  3QVD A;  4JAD A;  1PT1 A;  3GTO A;  1I50 A;  3GTJ A;  4GA5 A;  1QYB A;  3KYL A;  3LNL A;  2XJQ A;  2G5D A;  1YNJ D;  2CKC A;  4Q5G A;  1TWA A;  2R93 A;  2Z3Q B;  2WAQ A;  1S30 A;  2MS3 A;  1OGY A;  2R7Z A;  2AQL A;  3VPB E;  3IR5 A;  1R49 A;  5IZ2 A;  2M6O A;  1PT0 A;  3PIO 1;  2JIQ A;  2VPZ A;  3J7Y 1;  1VCX A;  7RXN A;  4NOH A;  1ODH A;  4FYD A;  2VL6 A;  1H5N A;  1SMU A;  2JIR A;  4CEH A;  3MAQ A;  4ZN1 B;  4LMO A;  2LCQ A;  1G8J A;  2EEO B;  4F3E A;  1GE9 A;  2KI8 A;  1JYB A;  2VUM A;  3PKI A;  3K35 A;  1R0F A;  2VPW A;  3PZA A;  2Z3R B;  1VZH A;  1WQH A;  4CRY G;  3GTG A;  3KYY A;  1SMW A;  2QL0 A;  3WVO A;  2M6P A;  4G6B A;  5MF6 A;  5CQG A;  2C45 A;  1B71 A;  1TWH A;  3B08 B;  3QQC E;  4FXD A;  5GAD c;  4JLR C;  1DMR A;  1IU6 A;  2GAE A;  2R92 A;  1IW7 D;  1SC7 A;  1RRJ A;  4KB2 A;  2O5J D;  1YUZ A;  3HU2 A;  3KYV A;  3PIP 1;  1CZ4 A;  1NH3 A;  3B0A B;  1KQF A;  2B5I D;  3CF2 A;  2X0Q A;  3RYG A;  1NXG A;  2JI2 A;  2M4Y A;  5MFP A;  4V19 6;  1PYQ A;  1E18 A;  1YK4 A;  4POF A;  1E32 A;  2FIP A;  3NFP I;  4XXB B;  3K58 A;  1R0J A;  1BQ9 A;  3GTM A;  5DYI A;  5AN9 H;  1CR5 A;  1PQE A;  1AW8 B;  3QWZ A;  1PQH A;  3KYU A;  2N1D B;  4CEJ A;  4KC6 A;  3RZ6 A;  2JIP A;  2XJS A;  2Y0S A;  3WWN B;  3P8B A;  2PSM C;  4AI3 A;  1FDI A;  1Q16 A;  1TWF A;  1TWG A;  2NVX A;  2PJH B;  4IP8 A;  1LKM A;  1YNN D;  4FGU A;  4RV0 A;  1RYT A;  4IP9 A;  6RXN A;  4ZN3 B;  3WWL A;  3GTP A;  2JIO A;  2JA6 A;  2ERJ A;  1R5Z A;  1NXE A;  2V45 A;  1FHH A;  4POG A;  3DMR A;  5B6C A;  1T8I A;  1R0H A;  2PMZ A;  3LRD A;  1UHE A;  3M4A A;  1A31 A;  2LPI A;  1RB9 A;  2X0P A;  2E2H A;  2DSX A;  3GTK A;  2H12 A;  2VK9 A;  2CW0 D;  5C18 A;  2A6H D;  3K59 A;  2C6B A;  1SIW A;  5DYG A;  4H3T A;  1YUX A;  1R0G A;  2VPY A;  1BRF A;  2PIC A;  1PYU B;  5EIN C;  4NOK A;  3U4Q A;  2G6G A;  1EH1 A;  1Y5I A;  4YWL A;  4KDI A;  2PVX A;  8RXN A;  2N3E A;  1H0H A;  1A35 A;  2K2D A;  2E7Z A;  1FDO A;  2NYA A;  3SS2 A;  4AHZ A;  5H1S c;  5FTK A;  1RDV A;  1T9Q A;  2F4Q A;  4CRZ A;  2ZIX A;  5T5I D;  3LPE B;  3KYX A;  1G8K A;  1T9O A;  1RDG A;  4AN8 A;  4GS7 D;  3A44 A;  2JI1 A;  1R27 A;  2PYA A;  2B9S B;  5JVG 1;  4NOL A;  4DMR A;  1YLE A;  4K9F A;  5DM6 1;  3CQZ A;  2PPT A;  1SMM A;  1AA6 A;  4O26 A;  4LHL A;  4ME3 A;  1HQM D;  4C2M A;  1R0I A;  5MLC 9;  5GAH c;  5FTL A;  3K5O A;  5C1B A;  4AR5 A;  1TGO A;  2PI8 A;  1LPQ A;  1I3Q A;  2A68 D;  5EIO C;  1YK5 A;  2XJT A;  2A6E D;  1QCS A;  2JA5 A;  2KKD A;  3KYW A;  1WQF A;  2BE5 D;  4JAF A;  1C09 A;  4XGH A;  3ML1 A;  2YUJ A;  5IY0 A;  1RWD A;  4JAG A;  5C9H A;  3QQ7 A;  3LF9 A;  1YV1 A;  4KB4 A;  3QC8 A;  2CKA A;  1ZYR D;  1VZG A;  2WB1 A;  1LKP A;  2VPX A;  4B8C D;  4CS0 A;  3K5L A;  5FTM A;  2MX9 A;  1VZI A;  2NYD A;  3PLX B;  2JIM A;  2JA7 A;  5T5M D;  3K5N A;  1BFY A;  5DM7 1;  4AR4 A;  1OWC A;  1ZC1 A;  2K3O A;  1WLF A;  3LR2 A;  5FTJ A;  2XJU A;  1BQ8 A;  5JVH 1;  1IU5 A;  3K5M A;  4FBS A;  3TM7 B;  2X0O A;  2AYJ A;  4Q5V A;  1K83 A;  4CEI A;  2F5J A;  1BE7 A;  2V3B B;  2L0Z A;  1I6V D;  3IAY A;  1IRO A;  4AR6 A;  3HKZ A;  1S24 A;  2IV2 X;  3IU3 I;  3P9A A;  3DU6 A;  5EPP A;  4UY8 1;  4AI0 A;  2KN9 A;  1MIU A;  4AR3 A;  2PVE A;  4QCL A;  5MLC 3;  2C6A A;  1DMS A;  1R9T A;  1UHD A;  2XJV A;  3MPS A;  1EK8 A;  1DVB A;  2MX8 A;  4D3Z A;  4AI1 A;  1CAD A;  1IS1 A;  1WCM A;  1T9P A;  4YWM A;  5GAG c;  2V3V A;  3CZB A;  4TVM A;  4AHC A;  3SJR A;  4QIW A;  3PKJ A;  1TL8 A;  3K57 A;  3TIW A;  3U44 A;  5MFZ A;  5GAE c;  5AI2 A;  4D3Y A;  2K3Q A;  1RYQ A;  4U67 1;  4AHY A;  4KO8 A;  1S3S A;  2R4G A;  1S2Z A;  4AYB A;  1TWC A;  4NOM A;  4TPU A;  2DMR A;  1RR8 C;  3DU5 A;  1E60 A;  1SFO A;  1A36 A;  3MSU A;  2B63 A;  4AON B;  1QDN A;  5JSB B;  3GTQ A;  1K4T A;  1E61 A;  3P2A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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