2O5JD

Crystal structure of the t. thermophilus rnap polymerase elongation complex with the ntp substrate analog
Total Genus 275
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
275
sequence length
1504
structure length
1264
Chain Sequence
b'KKEVRKVRIALASPEKIRSWSYGEVEKPETINYRTLKPERDGLFDERIFGPIKDYECACGKYKRQRFEGKVCERCGVEVTKSIVRRYRMGHIELATPAAHIWFVKDVPSKIGTLLDLSATELEQVLYFSKYIVLDPKGAILNGVPVEKRQLLTDEEYRELRYGKQETYPLPPGVDALVKDGEEVVKGQELAPGVVSRLDGVALYRFASILVVKARVYPFEDDVEVSTGDRVAPGDVLADGGKVKSDVYGRVEVDLVRNVVRVVESYDIDARMGAEAIQQLLKELDLEALEKELLEEMKHPSRARRAKARKRLEVVRAFLDSGNRPEWMILEAVPVLPPDLRPMVQVDGGRFATSDLNDLYRRLINRNNRLKKLLAQGAPEIIIRNEKRMLQEAVDALLDNGRRGAPVTNPGSDRPLRSLTDILSGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKRMALELFKPFLLKKMEEKGIAPNVKAARRMLERQRDIKDEVWDALEEVIHGKVVLLNRAPTLHRLGIQAFQPVLVEGQSIQLHPLVCEAFNADFDGDQMAVHVPLSSFAQAEARIQMLSAHNLLSPASGEPLAKPSRDIILGLYYITQVRKEKKGAGLEFATPEEALAAHERGEVALNAPIKVAGRETSVGRLKYVFANPDEALLAVAHGIVDLQDVVTVRYMGKRLETSPGRILFARIVAEAVEDEKVAWELIQLDVPQEKNSLKDLVYQAFLRLGMEKTARLLDALKYYGFTFSTTSGITIGIDDAVIPEEKKQYLEEADRKLLQIEQAYEMGFLTDRERYDQILQLWTETTEKVTQAVFKNFEENYPFNPLYVMAQSGARGNPQQIRQLCGLRGLMQKPSGETFEVPVRSSFREGLTVLEYFISSHGARKGGADTALRTADSGYLTRKLVDVTHEIVVREADCGTTNYISVPLFQPDEVTRSLRLRKRADIEAGLYGRVLAREVEVLGVRLEEGRYLSMDDVHLLIKAAEAGEIQEVPVRSPLTCQTRYGVCQKCYGYDLSMARPVSIGEAVGIVAAQSIGEPGTQLTMRTFHTGGVAGAADITQGLPRVIELFEARRPKAKAIDPHQLLEAKGPEAVERYLVEEIQKVYRAQGVKLHDKHIEIVVRQMMKYVEVTDPGDSRLLEGQVLEKWDVEALNERLIAEGKTPVAWKPLLMGVTKSALSTKSWLSAASFQNTTHVLTEAAIAGKKDELIGLKENVILGRLIPAGTGSDFVRFTQVVDQKTLKAIEEARKEAVEA'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords 5'-D(P*CP*CP*CP*TP*GP*TP*CP*TP*GP*GP*CP*GP*TP*TP*CP*GP*CP*GP
publication title Structural basis for substrate loading in bacterial RNA polymerase.
pubmed doi rcsb
molecule tags Transferase/dna-rna hybrid
total genus 275
structure length 1264
sequence length 1504
chains with identical sequence N
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2006-12-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00623 RNA_pol_Rpb1_2 RNA polymerase Rpb1, domain 2
D PF04983 RNA_pol_Rpb1_3 RNA polymerase Rpb1, domain 3
D PF04997 RNA_pol_Rpb1_1 RNA polymerase Rpb1, domain 1
D PF04998 RNA_pol_Rpb1_5 RNA polymerase Rpb1, domain 5
D PF05000 RNA_pol_Rpb1_4 RNA polymerase Rpb1, domain 4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.132.30 Mainly Alpha Orthogonal Bundle Topoisomerase I; Chain A, domain 4 Topoisomerase I; Chain A, domain 4 2o5jD05
1.10.274.100 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 Enzyme I; Chain A, domain 2 2o5jD04
2.20.28.170 Mainly Beta Single Sheet Rubrerythrin, domain 2 Rubrerythrin, domain 2 2o5jD07
2.40.40.70 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 2o5jD03
2JA7A 3GTPA 1YNJD 1TWFA 2E2IA 1I50A 2VUMA 2YU9A 2JA6A 1Y1VA 2O5JD 3GTJA 1WCMA 2A69D 2CW0D 3FKIA 3GTQA 1I6VD 1TWGA 1TWAA 2R93A 2A6HD 1IW7D 2B63A 4C2MA 1R9TA 2BE5D 3GTLA 3GTKA 2NVXA 2WB1A 3GTOA 1ZYRD 1TWHA 1SFOA 1K83A 3GTGA 2R92A 1YNND 2Y0SA 3GTMA 2JA5A 2NVYA 1HQMD 1SMYD 3CQZA 4AYBA 2A6ED 1I3QA 2E2HA 1Y1WA 3HKZA 3H0GA 2A68D 2PMZA 2R7ZA 4QIWA 2WAQA 1TWCA
chains in the Genus database with same CATH superfamily
2ERSA 1DX8A 1FHMA 1VCXA 1S30A 3K59A 3VPBE 1NNQA 4Y7NL 1BFYA 2LYIA 3K7AL 5AI2A 3HOWL 1PQEA 3CF2A 3GTQA 4C5UA 1RB9A 1TWHL 4C2MA 3HJWB 1Y5IA 3HU1A 1PQFA 2R4GA 5GLXA 4JJOA 1YNND 3DU6A 1Y4ZA 4TVMA 2XJPA 1LKOA 1UHDA 1TWCL 1PQHA 5GM9A 1PYQA 3RZDL 3SULA 4A3JL 5JSBB 1BQ8A 2VK9A 6RXNA 3WWLA 5MFPA 1SMUA 1TGOA 4KC6A 3RYGA 1WQHA 3GTLL 1R9TL 4F3EA 3B08B 1DMRA 1PFUA 1EU1A 1WLFA 3I4ML 4KDIA 1ZYMA 5GAGc 1S3SA 1EH1A 2NVXA 2N3EA 2GMGA 5DM71 3S1ML 1OA7A 2ENGA 5GAEc 1IROA 3GTMA 4C6GA 3QQ8A 1Y1WA 5MLC3 2CR8A 4C3JL 2VUMA 4IP9A 1FDOA 2JA6A 2NYDA 1H7VA 3OUGA 3EZEA 3H3VM 2M4VA 5EPPA 5IP9L 1T9OA 3X2MA 2Y0NA 1CADA 4G6BA 1WQGA 5JVG1 1NXEA 4KDDA 3IR5A 3GTOA 2R92A 4LHLA 1I3QL 1YUXA 2DMRA 4O26A 5JVH1 2MS3A 1B71A 2LTHA 2XJVA 1DMSA 1PT1A 2VPXA 1YV1A 1I50L 1T9PA 1Y1VL 2MX8A 2JA7A 1IU5A 2V0EA 2L0ZA 3K5LA 3PL5A 3GTJL 3PO2L 5GADc 3PKJA 1R0FA 4AHYA 4V2QA 1FDIA 1BE7A 5IZ2A 3P8BA 1WCMA 4FGUA 4FYDA 4AHCA 3LR2A 3GTGL 3M4OL 2V3VA 3KYWA 1DD5A 2AUSB 1PPYA 1KQGA 4A3KL 3HU2A 2JIQA 5C4JL 3H0GL 2R7ZL 3MAQA 2YIIA 5FTMA 2AQLA 5C44L 3PWFA 2E2JL 8RXNA 2PNWA 2A68D 4BY1L 1IRNA 3A44A 3PO3L 1S24A 3DU5A 4NOLA 3MPSA 2RFKB 4AR5A 5B6CA 4A3CL 2PJHB 3X2IA 3S14L 2C45A 2N1DB 4V2RA 1A31A 4GFQA 3M3GA 1G8JA 4POFA 2XJSA 1BW3A 3LWPB 1A35A 2JA5L 2GAEA 1ODHA 1R0HA 1R0IA 5GAHc 3HKZA 4QIWA 1SMWA 5FTNA 4JADA 5IP7L 1PFVA 3LWRB 5C9HA 4X6AL 1Z92B 5T5ID 2QL0A 1E18A 3H99A 4K9FA 1AA6A 1I6VD 1TWGA 2C6BA 2G5DA 4CEJA 4GA6A 2NVTL 4CEHA 2AYJA 2BE5D 1RRJA 3CQZL 1EZAA 1K4SA 3KYYA 4TPUA 1AW8B 1BQ9A 3HKZP 1Y1WL 3ZG6A 4C2M1 1P7PA 4XGHA 1MIUA 1E61A 3SUMA 4C3IL 5DM61 2VUML 5M5WL 2E2IL 3J7Z1 4BABA 1YK4A 1V9MA 4FBSA 5C1BA 5EINC 3QWZA 2ZIXA 4FXDA 1VC3B 1I6HL 3H97A 4ZN3B 4BBSL 1TL8A 1OGYA 2CW0D 3FKIA 2HR5A 2VL6A 3HAXC 1TMOA 2K3NA 2HVYC 3GTOL 3HOVL 4IP8A 2B63A 2F4QA 1SFOL 2PVEA 3S15L 5M5XL 2MQAA 1E5VA 4A3LL 4Q5GA 1SMMA 4BBRL 4JCWA 3U44A 4A3EL 1L8FA 4A3FL 2H12A 2NVYA 1HQMD 3B0AB 3RZTA 3J7Y1 3S2DL 4AR3A 2M4YA 3GTPL 2F5JA 1OWBA 2Z3RB 2KN9A 1N10A 2V3BB 1PFYA 4JP6A 3MSUA 3SUKA 3X2JA 1WCML 4CS0A 1BRFA 4KODA 1QQTA 4Y52L 3K57A 2CKAA 3JR7A 2M6OA 5FJ8L 2CKCA 4ZN1B 4WFN1 1UHEA 1K83L 3PZAA 3K5NA 1FHHA 2K3QA 4AVRA 3P9AA 2Z3QB 4A3DL 1QCSA 1ZYRD 1TWHA 1RDVA 3X2GA 1R27A 5K2ME 5IYCL 2AQCA 3RZ6A 1DVBA 2JIOA 4A3IL 5EIOC 2R93L 2A6ED 2E2HA 4AR4A 5T5MD 5RXNA 1TWFL 2FIOA 3IAYA 3HOZL 1TWCA 2YU9L 3O5AA 1R49A 5MFZA 1Y2MA 3LPEB 2G6GA 4AZDA 4JLRC 2C6AA 4D3YA 4AAYA 3PLXB 4U671 1BW4A 2HWGA 1T6JA 1QYBA 4CRYG 4C5RA 4AR6A 4V196 4FERA 2JI1A 5FTKA 1B13A 7RXNA 3X2LA 1IW7D 4H3TA 1R9TA 3SS2A 2LPIA 1ZRPA 2WB1A 4ME3A 1SC7A 2Y0SA 2B9SB 2MP0A 2X0OA 1Q16A 4AYBA 1H0HA 1IU6A 1VZGA 1B2JA 4EJ3A 4NOKA 2J9UB 2MX9A 1LPQA 4D3ZA 5IYDL 3ML1A 1VZHA 3PKIA 1RDGA 3KYXA 1TWGL 4YWMA 4A3BL 4BY7L 3GTQL 2PVXA 2XJQA 5C4XL 4QCLA 5MLC9 3M3YL 1TWAA 3K58A 1LTLA 3S1NL 3GTKA 2X0PA 2Y0SP 4POGA 1PYUB 2EEOB 4KO8A 1S2ZA 3LWOB 3X2OA 1ZC1A 5C18A 4UY81 2JI3A 1ISEA 1I3QA 4CQ5A 4C5SA 5MF6A 4A93L 1YNJD 1QCVA 2X0QA 1VZIA 3H9BA 1YLEA 1I50A 3K5OA 1WQFA 3H9CA 3GTJA 3LRDA 5GLFA 5GLYA 1CZ4A 4L48A 3WWNB 1WC2A 2LPJA 2NVXL 3S17L 1T8IA 2E7ZA 1YK5A 1RYTA 4A3GL 2XJTA 3GTML 2B5ID 4BXXL 3LR8A 4LHNA 5AN9H 2V0FA 4FG4A 2PPTA 2APOB 5CQGA 4QIWP 3H0GA 2R7ZA 5M3FL 2V45A 4KB2A 1T6PA 3QQCE 2WAQA 4JAEA 1R7RA 5M5YL 2JA6L 3HOYL 2EZCA 3K35A 4JP7A 1PZXA 1LKMA 3EZBA 1G8KA 4AONB 1HD5A 4AN8A 5FLML 2PJJA 2M6PA 3IU3I 4AHXA 2K2DA 3LHPS 2R92L 2JA8L 1WJVA 1CR5A 3KYUA 2E2HL 3CZBA 3LNLA 4JAGA 1IS1A 2JA5A 5MGNA 2WAQP 3S1RL 2EY4E 2JA7L 5IY0A 3HOXL 4XXBB 5H1Sc 3KYVA 4E6YA 3U4QA 4YWLA 4DMRA 3HJYB 2KI8A 4NOMA 4ENGA 1EJ9A 4AHZA 4GA5A 3MQKB 3WVOA 1OWCA 2FIPA 4D7ZB 2A69D 3QQ7A 1E8JA 3QC8A 3FDJA 3PIP1 1PT0A 5DYIA 1B2OA 1A36A 1E32A 2PSMC 2IV2X 3X2PA 4Q5VA 5M3ML 3EZAA 3CQZA 4JS7A 3IR7A 3NFPI 3KYLA 2PYAA 2XJUA 2PMZA 2JIPA 1PFWA 4RXNA 4KDLA 1F4LA 2E2IA 2NYAA 3X2HA 1TWAL 5IYBL 4AI2A 4FFTA 5DYGA 2O5JD 1EK8A 3LR6A 4ZM7A 2YUJA 3X2KA 4KAWX 1C09A 3RZOL 3GTKL 3LWQB 3SJRA 2JIRA 2VPZA 1E60A 2BH0A 3GTLA 3X2NA 4L8IA 2VPYA 4RV0A 1SFOA 1CAAA 4NOHA 2XJRA 4GS7D 1H5NA 2VPWA 2PMZP 4BAAA 2RDVA 4FG2A 4KB4A 2HROA 4B8CD 1JYBA 1NXGA 3GTPA 3K5MA 3ENGA 5FTJA 2EZAA 2KKDA 4LMOA 2JIMA 1T9QA 2AE0X 1KQFA 5C3EL 3I4NL 3PIO1 1OA9A 3DMRA 2A6HD 1R0GA 3SUJA 2WB1P 2DSXA 1YUZA 4JAFA 1K83A 4AYBP 3TIWA 1NH3A 1RWDA 3TM7B 1SIWA 1Y698 3S16L 1EZBA 4A3ML 3D30A 2PICA 2R93A 2JI2A 1R0JA 4AI3A 4C3HL 1TWFA 3LF9A 2ERJA 2YU9A 3FKIL 5FTLA 1Y1VA 1R5ZA 5H4UA 5AI3A 3NZ4A 2PI8A 4AOKB 1CZ5A 1GE9A 1Q8IA 5JSNB 4AI1A 1K4TA 1RR8C 4CEIA 2LCQA 2B63L 2HCZX 3HU3A 4CRZA 3QVDA 3M4AA 2NAPA 2LKMB 2KQAA 4KLNA 3HOUL 2NVYL 3GTGA 3S1QL 3LWVB 3P2AA 1LKPA 3S2HL 1RYQA 4AHWA 1SMYD 2NVQL 4AI0A 4OYDB 1QDNA 3IR6A 1SEUA 2EZBA 2K3OA 1W27A
chains in the Genus database with same CATH topology
2ERSA 1DX8A 1FHMA 1VCXA 1S30A 3K59A 3VPBE 1NNQA 1BFYA 2LYIA 5AI2A 1PQEA 3CF2A 3GTQA 1RB9A 4C2MA 1Y5IA 3HU1A 1PQFA 2R4GA 1YNND 3DU6A 1Y4ZA 4TVMA 2XJPA 1LKOA 1UHDA 1PQHA 1PYQA 5JSBB 1BQ8A 2VK9A 6RXNA 3WWLA 5MFPA 1SMUA 1TGOA 4KC6A 3RYGA 1WQHA 4F3EA 3B08B 1DMRA 1EU1A 1WLFA 4KDIA 5GAGc 1S3SA 1EH1A 2NVXA 2N3EA 2GMGA 5DM71 5GAEc 1IROA 3GTMA 3QQ8A 1Y1WA 5MLC3 2CR8A 2VUMA 4IP9A 1FDOA 2JA6A 2NYDA 1H7VA 3OUGA 2M4VA 5EPPA 1T9OA 2Y0NA 1CADA 4G6BA 1WQGA 5JVG1 1NXEA 4KDDA 3IR5A 3GTOA 2R92A 4LHLA 1YUXA 2DMRA 4O26A 5JVH1 2MS3A 1B71A 2LTHA 2XJVA 1DMSA 1PT1A 2VPXA 1YV1A 1T9PA 2MX8A 2JA7A 1IU5A 2V0EA 2L0ZA 3K5LA 5GADc 3PKJA 1R0FA 4AHYA 1FDIA 1BE7A 5IZ2A 3P8BA 1WCMA 4FGUA 4FYDA 4AHCA 3LR2A 2V3VA 3KYWA 1DD5A 1PPYA 1KQGA 3HU2A 2JIQA 3MAQA 5FTMA 2AQLA 3PWFA 8RXNA 2PNWA 2A68D 1IRNA 3A44A 1S24A 3DU5A 4NOLA 3MPSA 4AR5A 5B6CA 2PJHB 2C45A 2N1DB 1A31A 4GFQA 1G8JA 4POFA 2XJSA 1A35A 2GAEA 1ODHA 1R0HA 1R0IA 5GAHc 3HKZA 4QIWA 1SMWA 5FTNA 4JADA 5C9HA 1Z92B 5T5ID 2QL0A 1E18A 4K9FA 1AA6A 1I6VD 1TWGA 2C6BA 2G5DA 4CEJA 4GA6A 4CEHA 2AYJA 2BE5D 1RRJA 3KYYA 1K4SA 4TPUA 1AW8B 1BQ9A 3ZG6A 4XGHA 1MIUA 1E61A 5DM61 3J7Z1 1YK4A 1V9MA 4FBSA 5C1BA 5EINC 3QWZA 2ZIXA 4FXDA 1VC3B 4ZN3B 1TL8A 1OGYA 2CW0D 3FKIA 2HR5A 2VL6A 1TMOA 2K3NA 4IP8A 2B63A 2F4QA 2PVEA 2MQAA 1E5VA 4Q5GA 1SMMA 3U44A 2H12A 2NVYA 1HQMD 3B0AB 3RZTA 3J7Y1 4AR3A 2M4YA 2F5JA 1OWBA 2Z3RB 2KN9A 2V3BB 3MSUA 4CS0A 1BRFA 4KODA 3K57A 2CKAA 2M6OA 2CKCA 4ZN1B 4WFN1 1UHEA 3PZAA 3K5NA 1FHHA 2K3QA 3P9AA 2Z3QB 1QCSA 1ZYRD 1TWHA 1RDVA 1R27A 5K2ME 3RZ6A 2JIOA 1DVBA 5EIOC 2A6ED 2E2HA 4AR4A 5T5MD 5RXNA 2FIOA 3IAYA 1TWCA 3O5AA 1R49A 5MFZA 3LPEB 2G6GA 4AZDA 4JLRC 2C6AA 4D3YA 4AAYA 3PLXB 4U671 1QYBA 4CRYG 4AR6A 4V196 5FTKA 2JI1A 1B13A 7RXNA 1IW7D 4H3TA 1R9TA 3SS2A 2LPIA 1ZRPA 2WB1A 4ME3A 1SC7A 2Y0SA 2B9SB 2X0OA 1Q16A 4AYBA 1H0HA 1IU6A 1VZGA 1B2JA 4EJ3A 4NOKA 2J9UB 2MX9A 1LPQA 4D3ZA 3ML1A 1VZHA 3PKIA 1RDGA 3KYXA 4YWMA 2PVXA 2XJQA 4QCLA 5MLC9 1TWAA 3K58A 1LTLA 3GTKA 2X0PA 4POGA 1PYUB 2EEOB 4KO8A 1S2ZA 1ZC1A 5C18A 4UY81 2JI3A 1ISEA 1I3QA 5MF6A 1YNJD 1QCVA 2X0QA 1VZIA 1YLEA 1I50A 3K5OA 1WQFA 3GTJA 3LRDA 5GLFA 1CZ4A 3WWNB 2LPJA 1T8IA 2E7ZA 1YK5A 1RYTA 2XJTA 2B5ID 3LR8A 4LHNA 5AN9H 2V0FA 2PPTA 5CQGA 3H0GA 2R7ZA 2V45A 4KB2A 3QQCE 4JAEA 2WAQA 1R7RA 3K35A 1LKMA 1G8KA 4AONB 4AN8A 2PJJA 2M6PA 3IU3I 4AHXA 2K2DA 3LHPS 1WJVA 1CR5A 3KYUA 3CZBA 3LNLA 4JAGA 1IS1A 2JA5A 5MGNA 5IY0A 4XXBB 5H1Sc 3KYVA 4E6YA 3U4QA 4YWLA 4DMRA 2KI8A 4NOMA 1EJ9A 4AHZA 4GA5A 3WVOA 1OWCA 2FIPA 4D7ZB 2A69D 3QQ7A 1E8JA 3QC8A 3PIP1 1PT0A 5DYIA 1B2OA 1A36A 1E32A 2PSMC 2IV2X 4Q5VA 3CQZA 3IR7A 3NFPI 3KYLA 2PYAA 2XJUA 2PMZA 2JIPA 4RXNA 4KDLA 2E2IA 2NYAA 4AI2A 5DYGA 2O5JD 1EK8A 3LR6A 2YUJA 4KAWX 1C09A 3SJRA 2JIRA 2VPZA 1E60A 3GTLA 4L8IA 2VPYA 4RV0A 1SFOA 1CAAA 4NOHA 2XJRA 4GS7D 1H5NA 2VPWA 2RDVA 4KB4A 4B8CD 1JYBA 1NXGA 3GTPA 3K5MA 5FTJA 2KKDA 4LMOA 2JIMA 1T9QA 2AE0X 1KQFA 3PIO1 3DMRA 2A6HD 1R0GA 2DSXA 1YUZA 4JAFA 1K83A 3TIWA 1NH3A 1RWDA 3TM7B 1SIWA 1Y698 2PICA 2R93A 2JI2A 1R0JA 4AI3A 1TWFA 3LF9A 2ERJA 2YU9A 5FTLA 1Y1VA 1R5ZA 4AOKB 5AI3A 1CZ5A 2PI8A 1GE9A 1Q8IA 5JSNB 4AI1A 1K4TA 1RR8C 4CEIA 2LCQA 3HU3A 4CRZA 3QVDA 3M4AA 2NAPA 2LKMB 4KLNA 3GTGA 3P2AA 1LKPA 1RYQA 4AHWA 1SMYD 4AI0A 4OYDB 1QDNA 3IR6A 1SEUA 2K3OA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JA7 A;  3GTP A;  1YNJ D;  1TWF A;  2E2I A;  1I50 A;  2VUM A;  2YU9 A;  2JA6 A;  1Y1V A;  2O5J D;  3GTJ A;  1WCM A;  2A69 D;  2CW0 D;  3FKI A;  3GTQ A;  1I6V D;  1TWG A;  1TWA A;  2R93 A;  2A6H D;  1IW7 D;  2B63 A;  4C2M A;  1R9T A;  2BE5 D;  3GTL A;  3GTK A;  2NVX A;  2WB1 A;  3GTO A;  1ZYR D;  1TWH A;  1SFO A;  1K83 A;  3GTG A;  2R92 A;  1YNN D;  2Y0S A;  3GTM A;  2JA5 A;  2NVY A;  1HQM D;  1SMY D;  3CQZ A;  4AYB A;  2A6E D;  1I3Q A;  2E2H A;  1Y1W A;  3HKZ A;  3H0G A;  2A68 D;  2PMZ A;  2R7Z A;  4QIW A;  2WAQ A;  1TWC A; 
#chains in the Genus database with same CATH topology
 2ERS A;  1DX8 A;  1FHM A;  1VCX A;  1S30 A;  3K59 A;  3VPB E;  1NNQ A;  4Y7N L;  1BFY A;  2LYI A;  3K7A L;  5AI2 A;  3HOW L;  1PQE A;  3CF2 A;  3GTQ A;  4C5U A;  1RB9 A;  1TWH L;  4C2M A;  3HJW B;  1Y5I A;  3HU1 A;  1PQF A;  2R4G A;  5GLX A;  4JJO A;  1YNN D;  3DU6 A;  1Y4Z A;  4TVM A;  2XJP A;  1LKO A;  1UHD A;  1TWC L;  1PQH A;  5GM9 A;  1PYQ A;  3RZD L;  3SUL A;  4A3J L;  5JSB B;  1BQ8 A;  2VK9 A;  6RXN A;  3WWL A;  5MFP A;  1SMU A;  1TGO A;  4KC6 A;  3RYG A;  1WQH A;  3GTL L;  1R9T L;  4F3E A;  3B08 B;  1DMR A;  1PFU A;  1EU1 A;  1WLF A;  3I4M L;  4KDI A;  1ZYM A;  5GAG c;  1S3S A;  1EH1 A;  2NVX A;  2N3E A;  2GMG A;  5DM7 1;  3S1M L;  1OA7 A;  2ENG A;  5GAE c;  1IRO A;  3GTM A;  4C6G A;  3QQ8 A;  1Y1W A;  5MLC 3;  2CR8 A;  4C3J L;  2VUM A;  4IP9 A;  1FDO A;  2JA6 A;  2NYD A;  1H7V A;  3OUG A;  3EZE A;  3H3V M;  2M4V A;  5EPP A;  5IP9 L;  1T9O A;  3X2M A;  2Y0N A;  1CAD A;  4G6B A;  1WQG A;  5JVG 1;  1NXE A;  4KDD A;  3IR5 A;  3GTO A;  2R92 A;  4LHL A;  1I3Q L;  1YUX A;  2DMR A;  4O26 A;  5JVH 1;  2MS3 A;  1B71 A;  2LTH A;  2XJV A;  1DMS A;  1PT1 A;  2VPX A;  1YV1 A;  1I50 L;  1T9P A;  1Y1V L;  2MX8 A;  2JA7 A;  1IU5 A;  2V0E A;  2L0Z A;  3K5L A;  3PL5 A;  3GTJ L;  3PO2 L;  5GAD c;  3PKJ A;  1R0F A;  4AHY A;  4V2Q A;  1FDI A;  1BE7 A;  5IZ2 A;  3P8B A;  1WCM A;  4FGU A;  4FYD A;  4AHC A;  3LR2 A;  3GTG L;  3M4O L;  2V3V A;  3KYW A;  1DD5 A;  2AUS B;  1PPY A;  1KQG A;  4A3K L;  3HU2 A;  2JIQ A;  5C4J L;  3H0G L;  2R7Z L;  3MAQ A;  2YII A;  5FTM A;  2AQL A;  5C44 L;  3PWF A;  2E2J L;  8RXN A;  2PNW A;  2A68 D;  4BY1 L;  1IRN A;  3A44 A;  3PO3 L;  1S24 A;  3DU5 A;  4NOL A;  3MPS A;  2RFK B;  4AR5 A;  5B6C A;  4A3C L;  2PJH B;  3X2I A;  3S14 L;  2C45 A;  2N1D B;  4V2R A;  1A31 A;  4GFQ A;  3M3G A;  1G8J A;  4POF A;  2XJS A;  1BW3 A;  3LWP B;  1A35 A;  2JA5 L;  2GAE A;  1ODH A;  1R0H A;  1R0I A;  5GAH c;  3HKZ A;  4QIW A;  1SMW A;  5FTN A;  4JAD A;  5IP7 L;  1PFV A;  3LWR B;  5C9H A;  4X6A L;  1Z92 B;  5T5I D;  2QL0 A;  1E18 A;  3H99 A;  4K9F A;  1AA6 A;  1I6V D;  1TWG A;  2C6B A;  2G5D A;  4CEJ A;  4GA6 A;  2NVT L;  4CEH A;  2AYJ A;  2BE5 D;  1RRJ A;  3CQZ L;  1EZA A;  1K4S A;  3KYY A;  4TPU A;  1AW8 B;  1BQ9 A;  3HKZ P;  1Y1W L;  3ZG6 A;  4C2M 1;  1P7P A;  4XGH A;  1MIU A;  1E61 A;  3SUM A;  4C3I L;  5DM6 1;  2VUM L;  5M5W L;  2E2I L;  3J7Z 1;  4BAB A;  1YK4 A;  1V9M A;  4FBS A;  5C1B A;  5EIN C;  3QWZ A;  2ZIX A;  4FXD A;  1VC3 B;  1I6H L;  3H97 A;  4ZN3 B;  4BBS L;  1TL8 A;  1OGY A;  2CW0 D;  3FKI A;  2HR5 A;  2VL6 A;  3HAX C;  1TMO A;  2K3N A;  2HVY C;  3GTO L;  3HOV L;  4IP8 A;  2B63 A;  2F4Q A;  1SFO L;  2PVE A;  3S15 L;  5M5X L;  2MQA A;  1E5V A;  4A3L L;  4Q5G A;  1SMM A;  4BBR L;  4JCW A;  3U44 A;  4A3E L;  1L8F A;  4A3F L;  2H12 A;  2NVY A;  1HQM D;  3B0A B;  3RZT A;  3J7Y 1;  3S2D L;  4AR3 A;  2M4Y A;  3GTP L;  2F5J A;  1OWB A;  2Z3R B;  2KN9 A;  1N10 A;  2V3B B;  1PFY A;  4JP6 A;  3MSU A;  3SUK A;  3X2J A;  1WCM L;  4CS0 A;  1BRF A;  4KOD A;  1QQT A;  4Y52 L;  3K57 A;  2CKA A;  3JR7 A;  2M6O A;  5FJ8 L;  2CKC A;  4ZN1 B;  4WFN 1;  1UHE A;  1K83 L;  3PZA A;  3K5N A;  1FHH A;  2K3Q A;  4AVR A;  3P9A A;  2Z3Q B;  4A3D L;  1QCS A;  1ZYR D;  1TWH A;  1RDV A;  3X2G A;  1R27 A;  5K2M E;  5IYC L;  2AQC A;  3RZ6 A;  1DVB A;  2JIO A;  4A3I L;  5EIO C;  2R93 L;  2A6E D;  2E2H A;  4AR4 A;  5T5M D;  5RXN A;  1TWF L;  2FIO A;  3IAY A;  3HOZ L;  1TWC A;  2YU9 L;  3O5A A;  1R49 A;  5MFZ A;  1Y2M A;  3LPE B;  2G6G A;  4AZD A;  4JLR C;  2C6A A;  4D3Y A;  4AAY A;  3PLX B;  4U67 1;  1BW4 A;  2HWG A;  1T6J A;  1QYB A;  4CRY G;  4C5R A;  4AR6 A;  4V19 6;  4FER A;  2JI1 A;  5FTK A;  1B13 A;  7RXN A;  3X2L A;  1IW7 D;  4H3T A;  1R9T A;  3SS2 A;  2LPI A;  1ZRP A;  2WB1 A;  4ME3 A;  1SC7 A;  2Y0S A;  2B9S B;  2MP0 A;  2X0O A;  1Q16 A;  4AYB A;  1H0H A;  1IU6 A;  1VZG A;  1B2J A;  4EJ3 A;  4NOK A;  2J9U B;  2MX9 A;  1LPQ A;  4D3Z A;  5IYD L;  3ML1 A;  1VZH A;  3PKI A;  1RDG A;  3KYX A;  1TWG L;  4YWM A;  4A3B L;  4BY7 L;  3GTQ L;  2PVX A;  2XJQ A;  5C4X L;  4QCL A;  5MLC 9;  3M3Y L;  1TWA A;  3K58 A;  1LTL A;  3S1N L;  3GTK A;  2X0P A;  2Y0S P;  4POG A;  1PYU B;  2EEO B;  4KO8 A;  1S2Z A;  3LWO B;  3X2O A;  1ZC1 A;  5C18 A;  4UY8 1;  2JI3 A;  1ISE A;  1I3Q A;  4CQ5 A;  4C5S A;  5MF6 A;  4A93 L;  1YNJ D;  1QCV A;  2X0Q A;  1VZI A;  3H9B A;  1YLE A;  1I50 A;  3K5O A;  1WQF A;  3H9C A;  3GTJ A;  3LRD A;  5GLF A;  5GLY A;  1CZ4 A;  4L48 A;  3WWN B;  1WC2 A;  2LPJ A;  2NVX L;  3S17 L;  1T8I A;  2E7Z A;  1YK5 A;  1RYT A;  4A3G L;  2XJT A;  3GTM L;  2B5I D;  4BXX L;  3LR8 A;  4LHN A;  5AN9 H;  2V0F A;  4FG4 A;  2PPT A;  2APO B;  5CQG A;  4QIW P;  3H0G A;  2R7Z A;  5M3F L;  2V45 A;  4KB2 A;  1T6P A;  3QQC E;  2WAQ A;  4JAE A;  1R7R A;  5M5Y L;  2JA6 L;  3HOY L;  2EZC A;  3K35 A;  4JP7 A;  1PZX A;  1LKM A;  3EZB A;  1G8K A;  4AON B;  1HD5 A;  4AN8 A;  5FLM L;  2PJJ A;  2M6P A;  3IU3 I;  4AHX A;  2K2D A;  3LHP S;  2R92 L;  2JA8 L;  1WJV A;  1CR5 A;  3KYU A;  2E2H L;  3CZB A;  3LNL A;  4JAG A;  1IS1 A;  2JA5 A;  5MGN A;  2WAQ P;  3S1R L;  2EY4 E;  2JA7 L;  5IY0 A;  3HOX L;  4XXB B;  5H1S c;  3KYV A;  4E6Y A;  3U4Q A;  4YWL A;  4DMR A;  3HJY B;  2KI8 A;  4NOM A;  4ENG A;  1EJ9 A;  4AHZ A;  4GA5 A;  3MQK B;  3WVO A;  1OWC A;  2FIP A;  4D7Z B;  2A69 D;  3QQ7 A;  1E8J A;  3QC8 A;  3FDJ A;  3PIP 1;  1PT0 A;  5DYI A;  1B2O A;  1A36 A;  1E32 A;  2PSM C;  2IV2 X;  3X2P A;  4Q5V A;  5M3M L;  3EZA A;  3CQZ A;  4JS7 A;  3IR7 A;  3NFP I;  3KYL A;  2PYA A;  2XJU A;  2PMZ A;  2JIP A;  1PFW A;  4RXN A;  4KDL A;  1F4L A;  2E2I A;  2NYA A;  3X2H A;  1TWA L;  5IYB L;  4AI2 A;  4FFT A;  5DYG A;  2O5J D;  1EK8 A;  3LR6 A;  4ZM7 A;  2YUJ A;  3X2K A;  4KAW X;  1C09 A;  3RZO L;  3GTK L;  3LWQ B;  3SJR A;  2JIR A;  2VPZ A;  1E60 A;  2BH0 A;  3GTL A;  3X2N A;  4L8I A;  2VPY A;  4RV0 A;  1SFO A;  1CAA A;  4NOH A;  2XJR A;  4GS7 D;  1H5N A;  2VPW A;  2PMZ P;  4BAA A;  2RDV A;  4FG2 A;  4KB4 A;  2HRO A;  4B8C D;  1JYB A;  1NXG A;  3GTP A;  3K5M A;  3ENG A;  5FTJ A;  2EZA A;  2KKD A;  4LMO A;  2JIM A;  1T9Q A;  2AE0 X;  1KQF A;  5C3E L;  3I4N L;  3PIO 1;  1OA9 A;  3DMR A;  2A6H D;  1R0G A;  3SUJ A;  2WB1 P;  2DSX A;  1YUZ A;  4JAF A;  1K83 A;  4AYB P;  3TIW A;  1NH3 A;  1RWD A;  3TM7 B;  1SIW A;  1Y69 8;  3S16 L;  1EZB A;  4A3M L;  3D30 A;  2PIC A;  2R93 A;  2JI2 A;  1R0J A;  4AI3 A;  4C3H L;  1TWF A;  3LF9 A;  2ERJ A;  2YU9 A;  3FKI L;  5FTL A;  1Y1V A;  1R5Z A;  5H4U A;  5AI3 A;  3NZ4 A;  2PI8 A;  4AOK B;  1CZ5 A;  1GE9 A;  1Q8I A;  5JSN B;  4AI1 A;  1K4T A;  1RR8 C;  4CEI A;  2LCQ A;  2B63 L;  2HCZ X;  3HU3 A;  4CRZ A;  3QVD A;  3M4A A;  2NAP A;  2LKM B;  2KQA A;  4KLN A;  3HOU L;  2NVY L;  3GTG A;  3S1Q L;  3LWV B;  3P2A A;  1LKP A;  3S2H L;  1RYQ A;  4AHW A;  1SMY D;  2NVQ L;  4AI0 A;  4OYD B;  1QDN A;  3IR6 A;  1SEU A;  2EZB A;  2K3O A;  1W27 A; 
#chains in the Genus database with same CATH homology
 2ERS A;  1DX8 A;  1FHM A;  1VCX A;  1S30 A;  3K59 A;  3VPB E;  1NNQ A;  1BFY A;  2LYI A;  5AI2 A;  1PQE A;  3CF2 A;  3GTQ A;  1RB9 A;  4C2M A;  1Y5I A;  3HU1 A;  1PQF A;  2R4G A;  1YNN D;  3DU6 A;  1Y4Z A;  4TVM A;  2XJP A;  1LKO A;  1UHD A;  1PQH A;  1PYQ A;  5JSB B;  1BQ8 A;  2VK9 A;  6RXN A;  3WWL A;  5MFP A;  1SMU A;  1TGO A;  4KC6 A;  3RYG A;  1WQH A;  4F3E A;  3B08 B;  1DMR A;  1EU1 A;  1WLF A;  4KDI A;  5GAG c;  1S3S A;  1EH1 A;  2NVX A;  2N3E A;  2GMG A;  5DM7 1;  5GAE c;  1IRO A;  3GTM A;  3QQ8 A;  1Y1W A;  5MLC 3;  2CR8 A;  2VUM A;  4IP9 A;  1FDO A;  2JA6 A;  2NYD A;  1H7V A;  3OUG A;  2M4V A;  5EPP A;  1T9O A;  2Y0N A;  1CAD A;  4G6B A;  1WQG A;  5JVG 1;  1NXE A;  4KDD A;  3IR5 A;  3GTO A;  2R92 A;  4LHL A;  1YUX A;  2DMR A;  4O26 A;  5JVH 1;  2MS3 A;  1B71 A;  2LTH A;  2XJV A;  1DMS A;  1PT1 A;  2VPX A;  1YV1 A;  1T9P A;  2MX8 A;  2JA7 A;  1IU5 A;  2V0E A;  2L0Z A;  3K5L A;  5GAD c;  3PKJ A;  1R0F A;  4AHY A;  1FDI A;  1BE7 A;  5IZ2 A;  3P8B A;  1WCM A;  4FGU A;  4FYD A;  4AHC A;  3LR2 A;  2V3V A;  3KYW A;  1DD5 A;  1PPY A;  1KQG A;  3HU2 A;  2JIQ A;  3MAQ A;  5FTM A;  2AQL A;  3PWF A;  8RXN A;  2PNW A;  2A68 D;  1IRN A;  3A44 A;  1S24 A;  3DU5 A;  4NOL A;  3MPS A;  4AR5 A;  5B6C A;  2PJH B;  2C45 A;  2N1D B;  1A31 A;  4GFQ A;  1G8J A;  4POF A;  2XJS A;  1A35 A;  2GAE A;  1ODH A;  1R0H A;  1R0I A;  5GAH c;  3HKZ A;  4QIW A;  1SMW A;  5FTN A;  4JAD A;  5C9H A;  1Z92 B;  5T5I D;  2QL0 A;  1E18 A;  4K9F A;  1AA6 A;  1I6V D;  1TWG A;  2C6B A;  2G5D A;  4CEJ A;  4GA6 A;  4CEH A;  2AYJ A;  2BE5 D;  1RRJ A;  3KYY A;  1K4S A;  4TPU A;  1AW8 B;  1BQ9 A;  3ZG6 A;  4XGH A;  1MIU A;  1E61 A;  5DM6 1;  3J7Z 1;  1YK4 A;  1V9M A;  4FBS A;  5C1B A;  5EIN C;  3QWZ A;  2ZIX A;  4FXD A;  1VC3 B;  4ZN3 B;  1TL8 A;  1OGY A;  2CW0 D;  3FKI A;  2HR5 A;  2VL6 A;  1TMO A;  2K3N A;  4IP8 A;  2B63 A;  2F4Q A;  2PVE A;  2MQA A;  1E5V A;  4Q5G A;  1SMM A;  3U44 A;  2H12 A;  2NVY A;  1HQM D;  3B0A B;  3RZT A;  3J7Y 1;  4AR3 A;  2M4Y A;  2F5J A;  1OWB A;  2Z3R B;  2KN9 A;  2V3B B;  3MSU A;  4CS0 A;  1BRF A;  4KOD A;  3K57 A;  2CKA A;  2M6O A;  2CKC A;  4ZN1 B;  4WFN 1;  1UHE A;  3PZA A;  3K5N A;  1FHH A;  2K3Q A;  3P9A A;  2Z3Q B;  1QCS A;  1ZYR D;  1TWH A;  1RDV A;  1R27 A;  5K2M E;  3RZ6 A;  2JIO A;  1DVB A;  5EIO C;  2A6E D;  2E2H A;  4AR4 A;  5T5M D;  5RXN A;  2FIO A;  3IAY A;  1TWC A;  3O5A A;  1R49 A;  5MFZ A;  3LPE B;  2G6G A;  4AZD A;  4JLR C;  2C6A A;  4D3Y A;  4AAY A;  3PLX B;  4U67 1;  1QYB A;  4CRY G;  4AR6 A;  4V19 6;  5FTK A;  2JI1 A;  1B13 A;  7RXN A;  1IW7 D;  4H3T A;  1R9T A;  3SS2 A;  2LPI A;  1ZRP A;  2WB1 A;  4ME3 A;  1SC7 A;  2Y0S A;  2B9S B;  2X0O A;  1Q16 A;  4AYB A;  1H0H A;  1IU6 A;  1VZG A;  1B2J A;  4EJ3 A;  4NOK A;  2J9U B;  2MX9 A;  1LPQ A;  4D3Z A;  3ML1 A;  1VZH A;  3PKI A;  1RDG A;  3KYX A;  4YWM A;  2PVX A;  2XJQ A;  4QCL A;  5MLC 9;  1TWA A;  3K58 A;  1LTL A;  3GTK A;  2X0P A;  4POG A;  1PYU B;  2EEO B;  4KO8 A;  1S2Z A;  1ZC1 A;  5C18 A;  4UY8 1;  2JI3 A;  1ISE A;  1I3Q A;  5MF6 A;  1YNJ D;  1QCV A;  2X0Q A;  1VZI A;  1YLE A;  1I50 A;  3K5O A;  1WQF A;  3GTJ A;  3LRD A;  5GLF A;  1CZ4 A;  3WWN B;  2LPJ A;  1T8I A;  2E7Z A;  1YK5 A;  1RYT A;  2XJT A;  2B5I D;  3LR8 A;  4LHN A;  5AN9 H;  2V0F A;  2PPT A;  5CQG A;  3H0G A;  2R7Z A;  2V45 A;  4KB2 A;  3QQC E;  4JAE A;  2WAQ A;  1R7R A;  3K35 A;  1LKM A;  1G8K A;  4AON B;  4AN8 A;  2PJJ A;  2M6P A;  3IU3 I;  4AHX A;  2K2D A;  3LHP S;  1WJV A;  1CR5 A;  3KYU A;  3CZB A;  3LNL A;  4JAG A;  1IS1 A;  2JA5 A;  5MGN A;  5IY0 A;  4XXB B;  5H1S c;  3KYV A;  4E6Y A;  3U4Q A;  4YWL A;  4DMR A;  2KI8 A;  4NOM A;  1EJ9 A;  4AHZ A;  4GA5 A;  3WVO A;  1OWC A;  2FIP A;  4D7Z B;  2A69 D;  3QQ7 A;  1E8J A;  3QC8 A;  3PIP 1;  1PT0 A;  5DYI A;  1B2O A;  1A36 A;  1E32 A;  2PSM C;  2IV2 X;  4Q5V A;  3CQZ A;  3IR7 A;  3NFP I;  3KYL A;  2PYA A;  2XJU A;  2PMZ A;  2JIP A;  4RXN A;  4KDL A;  2E2I A;  2NYA A;  4AI2 A;  5DYG A;  2O5J D;  1EK8 A;  3LR6 A;  2YUJ A;  4KAW X;  1C09 A;  3SJR A;  2JIR A;  2VPZ A;  1E60 A;  3GTL A;  4L8I A;  2VPY A;  4RV0 A;  1SFO A;  1CAA A;  4NOH A;  2XJR A;  4GS7 D;  1H5N A;  2VPW A;  2RDV A;  4KB4 A;  4B8C D;  1JYB A;  1NXG A;  3GTP A;  3K5M A;  5FTJ A;  2KKD A;  4LMO A;  2JIM A;  1T9Q A;  2AE0 X;  1KQF A;  3PIO 1;  3DMR A;  2A6H D;  1R0G A;  2DSX A;  1YUZ A;  4JAF A;  1K83 A;  3TIW A;  1NH3 A;  1RWD A;  3TM7 B;  1SIW A;  1Y69 8;  2PIC A;  2R93 A;  2JI2 A;  1R0J A;  4AI3 A;  1TWF A;  3LF9 A;  2ERJ A;  2YU9 A;  5FTL A;  1Y1V A;  1R5Z A;  4AOK B;  5AI3 A;  1CZ5 A;  2PI8 A;  1GE9 A;  1Q8I A;  5JSN B;  4AI1 A;  1K4T A;  1RR8 C;  4CEI A;  2LCQ A;  3HU3 A;  4CRZ A;  3QVD A;  3M4A A;  2NAP A;  2LKM B;  4KLN A;  3GTG A;  3P2A A;  1LKP A;  1RYQ A;  4AHW A;  1SMY D;  4AI0 A;  4OYD B;  1QDN A;  3IR6 A;  1SEU A;  2K3O A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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