2O5JD

Crystal structure of the t. thermophilus rnap polymerase elongation complex with the ntp substrate analog
Total Genus 275
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
275
sequence length
1504
structure length
1264
Chain Sequence
KKEVRKVRIALASPEKIRSWSYGEVEKPETINYRTLKPERDGLFDERIFGPIKDYECACGKYKRQRFEGKVCERCGVEVTKSIVRRYRMGHIELATPAAHIWFVKDVPSKIGTLLDLSATELEQVLYFSKYIVLDPKGAILNGVPVEKRQLLTDEEYRELRYGKQETYPLPPGVDALVKDGEEVVKGQELAPGVVSRLDGVALYRFASILVVKARVYPFEDDVEVSTGDRVAPGDVLADGGKVKSDVYGRVEVDLVRNVVRVVESYDIDARMGAEAIQQLLKELDLEALEKELLEEMKHPSRARRAKARKRLEVVRAFLDSGNRPEWMILEAVPVLPPDLRPMVQVDGGRFATSDLNDLYRRLINRNNRLKKLLAQGAPEIIIRNEKRMLQEAVDALLDNGRRGAPVTNPGSDRPLRSLTDILSGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKRMALELFKPFLLKKMEEKGIAPNVKAARRMLERQRDIKDEVWDALEEVIHGKVVLLNRAPTLHRLGIQAFQPVLVEGQSIQLHPLVCEAFNADFDGDQMAVHVPLSSFAQAEARIQMLSAHNLLSPASGEPLAKPSRDIILGLYYITQVRKEKKGAGLEFATPEEALAAHERGEVALNAPIKVAGRETSVGRLKYVFANPDEALLAVAHGIVDLQDVVTVRYMGKRLETSPGRILFARIVAEAVEDEKVAWELIQLDVPQEKNSLKDLVYQAFLRLGMEKTARLLDALKYYGFTFSTTSGITIGIDDAVIPEEKKQYLEEADRKLLQIEQAYEMGFLTDRERYDQILQLWTETTEKVTQAVFKNFEENYPFNPLYVMAQSGARGNPQQIRQLCGLRGLMQKPSGETFEVPVRSSFREGLTVLEYFISSHGARKGGADTALRTADSGYLTRKLVDVTHEIVVREADCGTTNYISVPLFQPDEVTRSLRLRKRADIEAGLYGRVLAREVEVLGVRLEEGRYLSMDDVHLLIKAAEAGEIQEVPVRSPLTCQTRYGVCQKCYGYDLSMARPVSIGEAVGIVAAQSIGEPGTQLTMRTFHTGGVAGAADITQGLPRVIELFEARRPKAKAIDPHQLLEAKGPEAVERYLVEEIQKVYRAQGVKLHDKHIEIVVRQMMKYVEVTDPGDSRLLEGQVLEKWDVEALNERLIAEGKTPVAWKPLLMGVTKSALSTKSWLSAASFQNTTHVLTEAAIAGKKDELIGLKENVILGRLIPAGTGSDFVRFTQVVDQKTLKAIEEARKEAVEA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for substrate loading in bacterial RNA polymerase.
pubmed doi rcsb
molecule tags Transferase/dna-rna hybrid
molecule keywords 5'-D(P*CP*CP*CP*TP*GP*TP*CP*TP*GP*GP*CP*GP*TP*TP*CP*GP*CP*GP
total genus 275
structure length 1264
sequence length 1504
chains with identical sequence N
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2006-12-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00623 RNA_pol_Rpb1_2 RNA polymerase Rpb1, domain 2
D PF04983 RNA_pol_Rpb1_3 RNA polymerase Rpb1, domain 3
D PF04997 RNA_pol_Rpb1_1 RNA polymerase Rpb1, domain 1
D PF04998 RNA_pol_Rpb1_5 RNA polymerase Rpb1, domain 5
D PF05000 RNA_pol_Rpb1_4 RNA polymerase Rpb1, domain 4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.132.30 Mainly Alpha Orthogonal Bundle Topoisomerase I; Chain A, domain 4 Topoisomerase I; Chain A, domain 4 2o5jD05
1.10.274.100 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 Enzyme I; Chain A, domain 2 2o5jD04
2.20.28.170 Mainly Beta Single Sheet Rubrerythrin, domain 2 Rubrerythrin, domain 2 2o5jD07
2.40.40.70 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 2o5jD03
2CW0D 2JA7A 2R7ZA 1TWHA 4C2MA 1YNJD 2E2HA 2WAQA 3H0GA 1R9TA 3GTGA 2R92A 2YU9A 1TWAA 1Y1WA 2Y0SA 2JA6A 1YNND 3FKIA 1I3QA 2WB1A 1TWGA 1TWFA 3HKZA 1TWCA 1SMYD 3GTLA 3GTQA 3GTMA 2A69D 2JA5A 1ZYRD 2A6ED 2NVYA 1I50A 2NVXA 1K83A 1SFOA 2BE5D 3GTJA 2VUMA 2R93A 1HQMD 1IW7D 2A68D 2A6HD 1Y1VA 3GTPA 2B63A 2O5JD 2PMZA 3CQZA 4QIWA 3GTOA 1WCMA 1I6VD 2E2IA 4AYBA 3GTKA
chains in the Genus database with same CATH superfamily
1R9TL 2MQAA 3H0GA 3GTGA 5MGNA 3KYYA 2Y0NA 2Z3QB 2EEOB 3LWPB 2AQCA 3K58A 3LR8A 5AI3A 2A69D 4YWLA 5GAHc 4FFTA 1K83L 5DM61 1PYQA 2K3NA 2MS3A 1R0FA 4AONB 3TM7B 1OA9A 4KDDA 1LTLA 4C5SA 4C3JL 2KI8A 3PO2L 3J7Z1 2K2DA 1R27A 3QWZA 5MF6A 1EH1A 3RZTA 2WB1P 2JI2A 2AE0X 4JP7A 5GLYA 3FKIL 1Y1WA 1Y5IA 4ENGA 1TWGL 3GTLL 3IR6A 1T6JA 1CZ4A 4EJ3A 1RYQA 1PT1A 1SC7A 2AYJA 4QIWP 4POGA 1Z92B 3S15L 1R0HA 2FIOA 4AYBP 4CEIA 3KYWA 2B63L 1E60A 2A6HD 3CQZL 2APOB 1WQHA 2LYIA 1PT0A 1Y2MA 4AN8A 3HOZL 5IYCL 3HOYL 4D3ZA 2X0OA 1DD5A 1N10A 2XJTA 2JA7L 4CRYG 2EZBA 3LR2A 1QDNA 1TWHL 2YU9L 1YNJD 4TVMA 1S24A 1IROA 1RB9A 4BY1L 4LMOA 2EZAA 1HD5A 1Y4ZA 2C6BA 2JA6A 3B0AB 3S1NL 2PJHB 3HKZA 4GS7D 2JA5L 3HAXC 1K4TA 3PZAA 4AI1A 4ME3A 4YWMA 5MLC9 1NXGA 1FHHA 2R93A 1YUZA 5FTJA 5EINC 1SIWA 4X6AL 4RV0A 3MPSA 1CAAA 1S2ZA 3K7AL 4E6YA 4JS7A 4ZN3B 3IU3I 2WAQA 1KQGA 4CRZA 2FIPA 6RXNA 1RDVA 5K2ME 3DU5A 4CEJA 1ZC1A 3IR5A 3K57A 4C5UA 1PQHA 1ISEA 3GTQA 3PL5A 2PYAA 2PMZP 1I50A 4JAFA 1SFOL 2DMRA 2LKMB 4NOLA 1V9MA 4C3IL 2DSXA 2ERJA 3RYGA 4Y52L 1PPYA 2YIIA 1WCMA 1EZBA 1DVBA 4V2RA 3P2AA 4JAEA 1G8KA 3I4ML 1GE9A 2PICA 1B13A 4KLNA 1YV1A 5C9HA 3X2IA 2Y0SA 1A36A 3JR7A 1TWCL 4AHXA 2NVXL 5C44L 3S1RL 1T9OA 1RYTA 7RXNA 2X0QA 3NZ4A 2NYAA 2VUMA 3U44A 2PSMC 3K5NA 1EU1A 2A68D 5GAEc 1Y1VA 1H7VA 3FDJA 3EZBA 2O5JD 4V196 2JIPA 1FHMA 1WQGA 2XJQA 1B2OA 1WQFA 2QL0A 3KYXA 4A3FL 1FDOA 3SUKA 1A31A 3H0GL 3GTGL 1PFVA 5IP7L 4JADA 4AR4A 4JP6A 2N3EA 4A3JL 3QVDA 2HCZX 4RXNA 5GLFA 3QQ8A 3IR7A 1LKMA 4A3IL 3M3GA 1BW4A 5C3EL 1OWBA 3GTML 1H5NA 4BY7L 1T6PA 5M3FL 1ZYRD 2V0FA 1E32A 1BW3A 3X2JA 2E7ZA 1LPQA 2VK9A 1PFWA 3PO3L 1VZIA 5FTKA 4C3HL 3HU3A 4AHZA 3SS2A 3S16L 3LWOB 4AYBA 3GTKA 5T5ID 1NNQA 2RDVA 2LCQA 5CQGA 3ML1A 4KDIA 2R92A 4QCLA 1SMWA 4AHYA 1PQFA 1TMOA 4A3KL 3QQ7A 1IU6A 4CS0A 2JIMA 2AUSB 2M6OA 2B5ID 2JIQA 5JVH1 2PVEA 5FTNA 1R49A 3SULA 2EZCA 2HR5A 2KN9A 1BQ9A 2JIRA 3IAYA 4AI0A 4FG4A 2JA8L 2JI3A 2EY4E 3A44A 1QYBA 1PQEA 1LKOA 3O5AA 3J7Y1 3HOXL 2PVXA 4OYDB 1K4SA 1R0IA 1R7RA 4XXBB 1E18A 2PJJA 1A35A 3PIO1 2JA6L 1TWAA 5C1BA 1I3QA 1TWGA 1TWFA 1YK4A 4ZN1B 2VL6A 3HOVL 3MAQA 4V2QA 4G6BA 3RZOL 2NVYA 2V3BB 3KYVA 5M5XL 4L8IA 3P9AA 3PWFA 2R93L 3MQKB 1EJ9A 5M5WL 3HJYB 3ENGA 1R5ZA 5T5MD 3GTPL 2B63A 2LPJA 4C5RA 2C45A 2E2IL 1I6VD 1DX8A 3PKIA 5DYIA 4KDLA 1VZGA 1UHEA 1TWHA 2ERSA 2V0EA 2J9UB 5DM71 2F5JA 1Q16A 1OGYA 1DMRA 2JA5A 3MSUA 5JVG1 3WWLA 3K5OA 2XJSA 3CZBA 2F4QA 2IV2X 3QQCE 2CR8A 4AHCA 3X2HA 3PKJA 1IRNA 5C4JL 5GAGc 4BABA 3RZDL 4WFN1 2YUJA 1IW7D 4AOKB 2GAEA 4BXXL 3GTOL 2VPZA 2VPWA 3X2LA 4O26A 4BAAA 3LWRB 1CZ5A 4F3EA 4KC6A 3P8BA 2R7ZA 4H3TA 1F4LA 3M4AA 2E2HA 4AR5A 4UY81 2M6PA 1B2JA 1YK5A 2ENGA 3X2OA 2V3VA 3LPEB 3K5MA 1VZHA 3S1QL 4AZDA 4JJOA 1SMYD 1OWCA 4BBSL 5FLML 4FGUA 2GMGA 2PPTA 1QCVA 1BRFA 4IP8A 2VUML 3HJWB 1SFOA 2K3QA 3LR6A 1P7PA 5IY0A 2XJRA 3LNLA 3ZG6A 2ZIXA 2H12A 4Q5GA 1IU5A 5FTMA 4AAYA 5B6CA 2KQAA 1BE7A 3DMRA 2M4VA 5H4UA 1R0GA 4TPUA 5FJ8L 2WB1A 1TWCA 4NOKA 2R4GA 1YLEA 5EPPA 5M5YL 3S2HL 4KO8A 8RXNA 2HVYC 1KQFA 1RRJA 4KODA 4A3DL 3HU2A 2BE5D 5DYGA 4GA5A 3GTJA 3SUMA 4U671 2VPXA 3I4NL 4QIWA 1SMUA 1ZYMA 2Y0SP 5C18A 1EK8A 3KYUA 4CEHA 1OA7A 4FG2A 2R92L 1ODHA 2E2JL 2M4YA 1G8JA 1T9QA 1R9TA 1CADA 5IP9L 4NOHA 1PFUA 2NVQL 1Y1WL 3S14L 4A3GL 1B71A 1NH3A 4KB2A 4ZM7A 3VPBE 1E5VA 3GTMA 3EZEA 4D7ZB 1QCSA 4AR6A 1SMMA 4IP9A 1K83A 2CKAA 4A3EL 3CF2A 2HROA 1BFYA 2PNWA 4KB4A 4FXDA 1PYUB 5EIOC 3PIP1 2B9SB 3TIWA 5GM9A 4BBRL 1BQ8A 2N1DB 3WVOA 2CW0D 3LWVB 1E61A 4C2MA 1ZRPA 3SUJA 3S17L 1TWAL 4FBSA 4LHNA 1I3QL 1AA6A 2C6AA 1TWFL 4JAGA 3S2DL 1YNND 3FKIA 5MFZA 2G6GA 3GTLA 2NVYL 3OUGA 1YUXA 2A6ED 3PLXB 1SEUA 4AI2A 4A3LL 5IYBL 2NAPA 1L8FA 1WLFA 1T8IA 4C6GA 2CKCA 4AR3A 4C2M1 1MIUA 1VC3B 2PMZA 3CQZA 2NYDA 2XJUA 3U4QA 4A3CL 3X2NA 3X2KA 4AHWA 3NFPI 2XJVA 2X0PA 1TGOA 1H0HA 2JA7A 3B08B 1RR8C 1NXEA 3H3VM 1IS1A 2YU9A 1WJVA 1RDGA 4JLRC 4K9FA 1JYBA 4A3ML 1DMSA 3HU1A 4KAWX 3GTQL 1WC2A 4POFA 1EZAA 4Y7NL 1I50L 2L0ZA 3SJRA 5GADc 3LF9A 5MLC3 4A93L 5C4XL 4DMRA 1E8JA 3GTPA 4CQ5A 2MX8A 1WCML 3H97A 5IYDL 2E2IA 1C09A 2MP0A 3EZAA 4AVRA 5GLXA 2R7ZL 1Y698 4FERA 1Q8IA 4NOMA 2E2HL 3S1ML 4GFQA 3HKZP 3H99A 3X2GA 3HOUL 1RWDA 3K59A 3RZ6A 1PZXA 2JI1A 2PI8A 3KYLA 2RFKB 3H9CA 4B8CD 3K5LA 3HOWL 2MX9A 4XGHA 2BH0A 2LPIA 2K3OA 3X2MA 5AN9H 1TL8A 1W27A 1UHDA 3D30A 5JSNB 5M3ML 4FYDA 5RXNA 1HQMD 1Y1VL 3LWQB 3M4OL 5JSBB 5MFPA 1FDIA 4L48A 4AI3A 4A3BL 2WAQP 3GTOA 2LTHA 1T9PA 4LHLA 1VCXA 2AQLA 2HWGA 2XJPA 3LRDA 1S30A 1R0JA 2G5DA 1I6HL 3X2PA 2KKDA 3H9BA 4D3YA 1QQTA 5AI2A 3WWNB 4JCWA 2NVXA 3GTJL 3QC8A 2NVTL 1PFYA 3M3YL 1CR5A 4GA6A 2JIOA 2VPYA 3DU6A 3LHPS 5IZ2A 5FTLA 2Z3RB 1LKPA 3K35A 3GTKL 4Q5VA 1S3SA 2V45A 1AW8B 5H1Sc
chains in the Genus database with same CATH topology
2MQAA 3H0GA 3GTGA 5MGNA 3KYYA 2Y0NA 2Z3QB 2EEOB 3K58A 3LR8A 5AI3A 2A69D 4YWLA 5GAHc 5DM61 1PYQA 2K3NA 2MS3A 1R0FA 4AONB 3TM7B 4KDDA 1LTLA 2KI8A 3J7Z1 2K2DA 1R27A 3QWZA 5MF6A 1EH1A 3RZTA 2JI2A 2AE0X 1Y1WA 1Y5IA 3IR6A 1CZ4A 4EJ3A 1RYQA 1PT1A 1SC7A 2AYJA 4POGA 1Z92B 1R0HA 2FIOA 4CEIA 3KYWA 1E60A 2A6HD 1WQHA 2LYIA 1PT0A 4AN8A 4D3ZA 2X0OA 1DD5A 2XJTA 4CRYG 3LR2A 1QDNA 1YNJD 4TVMA 1S24A 1IROA 1RB9A 4LMOA 1Y4ZA 2C6BA 2JA6A 3B0AB 2PJHB 3HKZA 4GS7D 1K4TA 3PZAA 4AI1A 4ME3A 4YWMA 5MLC9 1NXGA 1FHHA 2R93A 1YUZA 5FTJA 5EINC 1SIWA 4RV0A 3MPSA 1CAAA 1S2ZA 4E6YA 4ZN3B 3IU3I 2WAQA 1KQGA 4CRZA 2FIPA 6RXNA 1RDVA 5K2ME 3DU5A 4CEJA 1ZC1A 3IR5A 3K57A 1PQHA 1ISEA 3GTQA 2PYAA 1I50A 4JAFA 2DMRA 2LKMB 4NOLA 1V9MA 2DSXA 2ERJA 3RYGA 1PPYA 1WCMA 1DVBA 3P2AA 4JAEA 1G8KA 1GE9A 2PICA 1B13A 4KLNA 1YV1A 5C9HA 2Y0SA 1A36A 4AHXA 1T9OA 1RYTA 7RXNA 2X0QA 2NYAA 2VUMA 3U44A 2PSMC 3K5NA 1EU1A 2A68D 5GAEc 1Y1VA 1H7VA 2O5JD 4V196 2JIPA 1FHMA 1WQGA 2XJQA 1B2OA 1WQFA 2QL0A 3KYXA 1FDOA 1A31A 4JADA 4AR4A 2N3EA 3QVDA 4RXNA 5GLFA 3QQ8A 3IR7A 1LKMA 1OWBA 1H5NA 1ZYRD 2V0FA 1E32A 2E7ZA 1LPQA 2VK9A 1VZIA 5FTKA 3HU3A 4AHZA 3SS2A 4AYBA 3GTKA 5T5ID 1NNQA 2RDVA 2LCQA 5CQGA 3ML1A 4KDIA 2R92A 4QCLA 1SMWA 4AHYA 1PQFA 1TMOA 3QQ7A 1IU6A 4CS0A 2JIMA 2M6OA 2B5ID 2JIQA 5JVH1 2PVEA 5FTNA 1R49A 2HR5A 2KN9A 2JIRA 1BQ9A 3IAYA 4AI0A 2JI3A 3A44A 1QYBA 1PQEA 1LKOA 3O5AA 3J7Y1 2PVXA 4OYDB 1K4SA 1R0IA 1R7RA 4XXBB 1E18A 2PJJA 1A35A 3PIO1 1TWAA 5C1BA 1I3QA 1TWGA 1TWFA 1YK4A 4ZN1B 2VL6A 3MAQA 4G6BA 2NVYA 2V3BB 3KYVA 4L8IA 3P9AA 3PWFA 1EJ9A 1R5ZA 5T5MD 2B63A 2LPJA 2C45A 1I6VD 1DX8A 3PKIA 5DYIA 4KDLA 1VZGA 1UHEA 1TWHA 2ERSA 2V0EA 2J9UB 5DM71 2F5JA 1Q16A 1OGYA 1DMRA 2JA5A 3MSUA 5JVG1 3WWLA 3K5OA 2XJSA 3CZBA 2F4QA 2IV2X 3QQCE 2CR8A 4AHCA 3PKJA 1IRNA 5GAGc 4WFN1 2YUJA 1IW7D 4AOKB 2GAEA 2VPWA 2VPZA 4O26A 1CZ5A 4F3EA 4KC6A 3P8BA 2R7ZA 4H3TA 3M4AA 2E2HA 4AR5A 4UY81 2M6PA 1B2JA 1YK5A 2V3VA 3LPEB 3K5MA 1VZHA 4AZDA 1SMYD 1OWCA 4FGUA 2GMGA 2PPTA 1QCVA 1BRFA 4IP8A 1SFOA 2K3QA 3LR6A 5IY0A 2XJRA 3LNLA 3ZG6A 2ZIXA 2H12A 4Q5GA 1IU5A 5FTMA 4AAYA 5B6CA 1BE7A 3DMRA 2M4VA 1R0GA 4TPUA 2WB1A 1TWCA 4NOKA 2R4GA 1YLEA 5EPPA 4KO8A 8RXNA 1KQFA 1RRJA 4KODA 3HU2A 5DYGA 2BE5D 4GA5A 3GTJA 4U671 2VPXA 4QIWA 1SMUA 5C18A 1EK8A 3KYUA 4CEHA 1ODHA 2M4YA 1G8JA 1T9QA 1R9TA 1CADA 4NOHA 1B71A 1NH3A 4KB2A 3VPBE 1E5VA 3GTMA 4D7ZB 1QCSA 4AR6A 1SMMA 4IP9A 1K83A 2CKAA 3CF2A 1BFYA 2PNWA 4KB4A 4FXDA 1PYUB 5EIOC 3PIP1 2B9SB 3TIWA 1BQ8A 2N1DB 3WVOA 2CW0D 1E61A 4C2MA 1ZRPA 4FBSA 4LHNA 1AA6A 2C6AA 4JAGA 1YNND 3FKIA 5MFZA 2G6GA 3GTLA 3OUGA 1YUXA 2A6ED 3PLXB 1SEUA 4AI2A 2NAPA 1WLFA 1T8IA 2CKCA 4AR3A 1MIUA 1VC3B 2PMZA 3CQZA 2NYDA 2XJUA 3U4QA 4AHWA 3NFPI 2XJVA 2X0PA 1TGOA 1H0HA 2JA7A 3B08B 1RR8C 1NXEA 1IS1A 2YU9A 1WJVA 1RDGA 4JLRC 4K9FA 1JYBA 3HU1A 1DMSA 4KAWX 4POFA 2L0ZA 3SJRA 5GADc 3LF9A 5MLC3 4DMRA 1E8JA 3GTPA 2MX8A 2E2IA 1C09A 1Y698 1Q8IA 4NOMA 4GFQA 1RWDA 3K59A 3RZ6A 2JI1A 2PI8A 3KYLA 4B8CD 3K5LA 2MX9A 4XGHA 2LPIA 2K3OA 5AN9H 1TL8A 1UHDA 5JSNB 4FYDA 5RXNA 1HQMD 5JSBB 5MFPA 1FDIA 4AI3A 3GTOA 2LTHA 1T9PA 4LHLA 1VCXA 2AQLA 2XJPA 3LRDA 1S30A 1R0JA 2G5DA 2KKDA 4D3YA 5AI2A 3WWNB 2NVXA 3QC8A 1CR5A 4GA6A 2JIOA 2VPYA 3DU6A 3LHPS 5IZ2A 5FTLA 2Z3RB 1LKPA 3K35A 4Q5VA 1S3SA 2V45A 1AW8B 5H1Sc
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CW0 D;  2JA7 A;  2R7Z A;  1TWH A;  4C2M A;  1YNJ D;  2E2H A;  2WAQ A;  3H0G A;  1R9T A;  3GTG A;  2R92 A;  2YU9 A;  1TWA A;  1Y1W A;  2Y0S A;  2JA6 A;  1YNN D;  3FKI A;  1I3Q A;  2WB1 A;  1TWG A;  1TWF A;  3HKZ A;  1TWC A;  1SMY D;  3GTL A;  3GTQ A;  3GTM A;  2A69 D;  2JA5 A;  1ZYR D;  2A6E D;  2NVY A;  1I50 A;  2NVX A;  1K83 A;  1SFO A;  2BE5 D;  3GTJ A;  2VUM A;  2R93 A;  1HQM D;  1IW7 D;  2A68 D;  2A6H D;  1Y1V A;  3GTP A;  2B63 A;  2O5J D;  2PMZ A;  3CQZ A;  4QIW A;  3GTO A;  1WCM A;  1I6V D;  2E2I A;  4AYB A;  3GTK A; 
#chains in the Genus database with same CATH topology
 1R9T L;  2MQA A;  3H0G A;  3GTG A;  5MGN A;  3KYY A;  2Y0N A;  2Z3Q B;  2EEO B;  3LWP B;  2AQC A;  3K58 A;  3LR8 A;  5AI3 A;  2A69 D;  4YWL A;  5GAH c;  4FFT A;  1K83 L;  5DM6 1;  1PYQ A;  2K3N A;  2MS3 A;  1R0F A;  4AON B;  3TM7 B;  1OA9 A;  4KDD A;  1LTL A;  4C5S A;  4C3J L;  2KI8 A;  3PO2 L;  3J7Z 1;  2K2D A;  1R27 A;  3QWZ A;  5MF6 A;  1EH1 A;  3RZT A;  2WB1 P;  2JI2 A;  2AE0 X;  4JP7 A;  5GLY A;  3FKI L;  1Y1W A;  1Y5I A;  4ENG A;  1TWG L;  3GTL L;  3IR6 A;  1T6J A;  1CZ4 A;  4EJ3 A;  1RYQ A;  1PT1 A;  1SC7 A;  2AYJ A;  4QIW P;  4POG A;  1Z92 B;  3S15 L;  1R0H A;  2FIO A;  4AYB P;  4CEI A;  3KYW A;  2B63 L;  1E60 A;  2A6H D;  3CQZ L;  2APO B;  1WQH A;  2LYI A;  1PT0 A;  1Y2M A;  4AN8 A;  3HOZ L;  5IYC L;  3HOY L;  4D3Z A;  2X0O A;  1DD5 A;  1N10 A;  2XJT A;  2JA7 L;  4CRY G;  2EZB A;  3LR2 A;  1QDN A;  1TWH L;  2YU9 L;  1YNJ D;  4TVM A;  1S24 A;  1IRO A;  1RB9 A;  4BY1 L;  4LMO A;  2EZA A;  1HD5 A;  1Y4Z A;  2C6B A;  2JA6 A;  3B0A B;  3S1N L;  2PJH B;  3HKZ A;  4GS7 D;  2JA5 L;  3HAX C;  1K4T A;  3PZA A;  4AI1 A;  4ME3 A;  4YWM A;  5MLC 9;  1NXG A;  1FHH A;  2R93 A;  1YUZ A;  5FTJ A;  5EIN C;  1SIW A;  4X6A L;  4RV0 A;  3MPS A;  1CAA A;  1S2Z A;  3K7A L;  4E6Y A;  4JS7 A;  4ZN3 B;  3IU3 I;  2WAQ A;  1KQG A;  4CRZ A;  2FIP A;  6RXN A;  1RDV A;  5K2M E;  3DU5 A;  4CEJ A;  1ZC1 A;  3IR5 A;  3K57 A;  4C5U A;  1PQH A;  1ISE A;  3GTQ A;  3PL5 A;  2PYA A;  2PMZ P;  1I50 A;  4JAF A;  1SFO L;  2DMR A;  2LKM B;  4NOL A;  1V9M A;  4C3I L;  2DSX A;  2ERJ A;  3RYG A;  4Y52 L;  1PPY A;  2YII A;  1WCM A;  1EZB A;  1DVB A;  4V2R A;  3P2A A;  4JAE A;  1G8K A;  3I4M L;  1GE9 A;  2PIC A;  1B13 A;  4KLN A;  1YV1 A;  5C9H A;  3X2I A;  2Y0S A;  1A36 A;  3JR7 A;  1TWC L;  4AHX A;  2NVX L;  5C44 L;  3S1R L;  1T9O A;  1RYT A;  7RXN A;  2X0Q A;  3NZ4 A;  2NYA A;  2VUM A;  3U44 A;  2PSM C;  3K5N A;  1EU1 A;  2A68 D;  5GAE c;  1Y1V A;  1H7V A;  3FDJ A;  3EZB A;  2O5J D;  4V19 6;  2JIP A;  1FHM A;  1WQG A;  2XJQ A;  1B2O A;  1WQF A;  2QL0 A;  3KYX A;  4A3F L;  1FDO A;  3SUK A;  1A31 A;  3H0G L;  3GTG L;  1PFV A;  5IP7 L;  4JAD A;  4AR4 A;  4JP6 A;  2N3E A;  4A3J L;  3QVD A;  2HCZ X;  4RXN A;  5GLF A;  3QQ8 A;  3IR7 A;  1LKM A;  4A3I L;  3M3G A;  1BW4 A;  5C3E L;  1OWB A;  3GTM L;  1H5N A;  4BY7 L;  1T6P A;  5M3F L;  1ZYR D;  2V0F A;  1E32 A;  1BW3 A;  3X2J A;  2E7Z A;  1LPQ A;  2VK9 A;  1PFW A;  3PO3 L;  1VZI A;  5FTK A;  4C3H L;  3HU3 A;  4AHZ A;  3SS2 A;  3S16 L;  3LWO B;  4AYB A;  3GTK A;  5T5I D;  1NNQ A;  2RDV A;  2LCQ A;  5CQG A;  3ML1 A;  4KDI A;  2R92 A;  4QCL A;  1SMW A;  4AHY A;  1PQF A;  1TMO A;  4A3K L;  3QQ7 A;  1IU6 A;  4CS0 A;  2JIM A;  2AUS B;  2M6O A;  2B5I D;  2JIQ A;  5JVH 1;  2PVE A;  5FTN A;  1R49 A;  3SUL A;  2EZC A;  2HR5 A;  2KN9 A;  1BQ9 A;  2JIR A;  3IAY A;  4AI0 A;  4FG4 A;  2JA8 L;  2JI3 A;  2EY4 E;  3A44 A;  1QYB A;  1PQE A;  1LKO A;  3O5A A;  3J7Y 1;  3HOX L;  2PVX A;  4OYD B;  1K4S A;  1R0I A;  1R7R A;  4XXB B;  1E18 A;  2PJJ A;  1A35 A;  3PIO 1;  2JA6 L;  1TWA A;  5C1B A;  1I3Q A;  1TWG A;  1TWF A;  1YK4 A;  4ZN1 B;  2VL6 A;  3HOV L;  3MAQ A;  4V2Q A;  4G6B A;  3RZO L;  2NVY A;  2V3B B;  3KYV A;  5M5X L;  4L8I A;  3P9A A;  3PWF A;  2R93 L;  3MQK B;  1EJ9 A;  5M5W L;  3HJY B;  3ENG A;  1R5Z A;  5T5M D;  3GTP L;  2B63 A;  2LPJ A;  4C5R A;  2C45 A;  2E2I L;  1I6V D;  1DX8 A;  3PKI A;  5DYI A;  4KDL A;  1VZG A;  1UHE A;  1TWH A;  2ERS A;  2V0E A;  2J9U B;  5DM7 1;  2F5J A;  1Q16 A;  1OGY A;  1DMR A;  2JA5 A;  3MSU A;  5JVG 1;  3WWL A;  3K5O A;  2XJS A;  3CZB A;  2F4Q A;  2IV2 X;  3QQC E;  2CR8 A;  4AHC A;  3X2H A;  3PKJ A;  1IRN A;  5C4J L;  5GAG c;  4BAB A;  3RZD L;  4WFN 1;  2YUJ A;  1IW7 D;  4AOK B;  2GAE A;  4BXX L;  3GTO L;  2VPZ A;  2VPW A;  3X2L A;  4O26 A;  4BAA A;  3LWR B;  1CZ5 A;  4F3E A;  4KC6 A;  3P8B A;  2R7Z A;  4H3T A;  1F4L A;  3M4A A;  2E2H A;  4AR5 A;  4UY8 1;  2M6P A;  1B2J A;  1YK5 A;  2ENG A;  3X2O A;  2V3V A;  3LPE B;  3K5M A;  1VZH A;  3S1Q L;  4AZD A;  4JJO A;  1SMY D;  1OWC A;  4BBS L;  5FLM L;  4FGU A;  2GMG A;  2PPT A;  1QCV A;  1BRF A;  4IP8 A;  2VUM L;  3HJW B;  1SFO A;  2K3Q A;  3LR6 A;  1P7P A;  5IY0 A;  2XJR A;  3LNL A;  3ZG6 A;  2ZIX A;  2H12 A;  4Q5G A;  1IU5 A;  5FTM A;  4AAY A;  5B6C A;  2KQA A;  1BE7 A;  3DMR A;  2M4V A;  5H4U A;  1R0G A;  4TPU A;  5FJ8 L;  2WB1 A;  1TWC A;  4NOK A;  2R4G A;  1YLE A;  5EPP A;  5M5Y L;  3S2H L;  4KO8 A;  8RXN A;  2HVY C;  1KQF A;  1RRJ A;  4KOD A;  4A3D L;  3HU2 A;  2BE5 D;  5DYG A;  4GA5 A;  3GTJ A;  3SUM A;  4U67 1;  2VPX A;  3I4N L;  4QIW A;  1SMU A;  1ZYM A;  2Y0S P;  5C18 A;  1EK8 A;  3KYU A;  4CEH A;  1OA7 A;  4FG2 A;  2R92 L;  1ODH A;  2E2J L;  2M4Y A;  1G8J A;  1T9Q A;  1R9T A;  1CAD A;  5IP9 L;  4NOH A;  1PFU A;  2NVQ L;  1Y1W L;  3S14 L;  4A3G L;  1B71 A;  1NH3 A;  4KB2 A;  4ZM7 A;  3VPB E;  1E5V A;  3GTM A;  3EZE A;  4D7Z B;  1QCS A;  4AR6 A;  1SMM A;  4IP9 A;  1K83 A;  2CKA A;  4A3E L;  3CF2 A;  2HRO A;  1BFY A;  2PNW A;  4KB4 A;  4FXD A;  1PYU B;  5EIO C;  3PIP 1;  2B9S B;  3TIW A;  5GM9 A;  4BBR L;  1BQ8 A;  2N1D B;  3WVO A;  2CW0 D;  3LWV B;  1E61 A;  4C2M A;  1ZRP A;  3SUJ A;  3S17 L;  1TWA L;  4FBS A;  4LHN A;  1I3Q L;  1AA6 A;  2C6A A;  1TWF L;  4JAG A;  3S2D L;  1YNN D;  3FKI A;  5MFZ A;  2G6G A;  3GTL A;  2NVY L;  3OUG A;  1YUX A;  2A6E D;  3PLX B;  1SEU A;  4AI2 A;  4A3L L;  5IYB L;  2NAP A;  1L8F A;  1WLF A;  1T8I A;  4C6G A;  2CKC A;  4AR3 A;  4C2M 1;  1MIU A;  1VC3 B;  2PMZ A;  3CQZ A;  2NYD A;  2XJU A;  3U4Q A;  4A3C L;  3X2N A;  3X2K A;  4AHW A;  3NFP I;  2XJV A;  2X0P A;  1TGO A;  1H0H A;  2JA7 A;  3B08 B;  1RR8 C;  1NXE A;  3H3V M;  1IS1 A;  2YU9 A;  1WJV A;  1RDG A;  4JLR C;  4K9F A;  1JYB A;  4A3M L;  1DMS A;  3HU1 A;  4KAW X;  3GTQ L;  1WC2 A;  4POF A;  1EZA A;  4Y7N L;  1I50 L;  2L0Z A;  3SJR A;  5GAD c;  3LF9 A;  5MLC 3;  4A93 L;  5C4X L;  4DMR A;  1E8J A;  3GTP A;  4CQ5 A;  2MX8 A;  1WCM L;  3H97 A;  5IYD L;  2E2I A;  1C09 A;  2MP0 A;  3EZA A;  4AVR A;  5GLX A;  2R7Z L;  1Y69 8;  4FER A;  1Q8I A;  4NOM A;  2E2H L;  3S1M L;  4GFQ A;  3HKZ P;  3H99 A;  3X2G A;  3HOU L;  1RWD A;  3K59 A;  3RZ6 A;  1PZX A;  2JI1 A;  2PI8 A;  3KYL A;  2RFK B;  3H9C A;  4B8C D;  3K5L A;  3HOW L;  2MX9 A;  4XGH A;  2BH0 A;  2LPI A;  2K3O A;  3X2M A;  5AN9 H;  1TL8 A;  1W27 A;  1UHD A;  3D30 A;  5JSN B;  5M3M L;  4FYD A;  5RXN A;  1HQM D;  1Y1V L;  3LWQ B;  3M4O L;  5JSB B;  5MFP A;  1FDI A;  4L48 A;  4AI3 A;  4A3B L;  2WAQ P;  3GTO A;  2LTH A;  1T9P A;  4LHL A;  1VCX A;  2AQL A;  2HWG A;  2XJP A;  3LRD A;  1S30 A;  1R0J A;  2G5D A;  1I6H L;  3X2P A;  2KKD A;  3H9B A;  4D3Y A;  1QQT A;  5AI2 A;  3WWN B;  4JCW A;  2NVX A;  3GTJ L;  3QC8 A;  2NVT L;  1PFY A;  3M3Y L;  1CR5 A;  4GA6 A;  2JIO A;  2VPY A;  3DU6 A;  3LHP S;  5IZ2 A;  5FTL A;  2Z3R B;  1LKP A;  3K35 A;  3GTK L;  4Q5V A;  1S3S A;  2V45 A;  1AW8 B;  5H1S c; 
#chains in the Genus database with same CATH homology
 2MQA A;  3H0G A;  3GTG A;  5MGN A;  3KYY A;  2Y0N A;  2Z3Q B;  2EEO B;  3K58 A;  3LR8 A;  5AI3 A;  2A69 D;  4YWL A;  5GAH c;  5DM6 1;  1PYQ A;  2K3N A;  2MS3 A;  1R0F A;  4AON B;  3TM7 B;  4KDD A;  1LTL A;  2KI8 A;  3J7Z 1;  2K2D A;  1R27 A;  3QWZ A;  5MF6 A;  1EH1 A;  3RZT A;  2JI2 A;  2AE0 X;  1Y1W A;  1Y5I A;  3IR6 A;  1CZ4 A;  4EJ3 A;  1RYQ A;  1PT1 A;  1SC7 A;  2AYJ A;  4POG A;  1Z92 B;  1R0H A;  2FIO A;  4CEI A;  3KYW A;  1E60 A;  2A6H D;  1WQH A;  2LYI A;  1PT0 A;  4AN8 A;  4D3Z A;  2X0O A;  1DD5 A;  2XJT A;  4CRY G;  3LR2 A;  1QDN A;  1YNJ D;  4TVM A;  1S24 A;  1IRO A;  1RB9 A;  4LMO A;  1Y4Z A;  2C6B A;  2JA6 A;  3B0A B;  2PJH B;  3HKZ A;  4GS7 D;  1K4T A;  3PZA A;  4AI1 A;  4ME3 A;  4YWM A;  5MLC 9;  1NXG A;  1FHH A;  2R93 A;  1YUZ A;  5FTJ A;  5EIN C;  1SIW A;  4RV0 A;  3MPS A;  1CAA A;  1S2Z A;  4E6Y A;  4ZN3 B;  3IU3 I;  2WAQ A;  1KQG A;  4CRZ A;  2FIP A;  6RXN A;  1RDV A;  5K2M E;  3DU5 A;  4CEJ A;  1ZC1 A;  3IR5 A;  3K57 A;  1PQH A;  1ISE A;  3GTQ A;  2PYA A;  1I50 A;  4JAF A;  2DMR A;  2LKM B;  4NOL A;  1V9M A;  2DSX A;  2ERJ A;  3RYG A;  1PPY A;  1WCM A;  1DVB A;  3P2A A;  4JAE A;  1G8K A;  1GE9 A;  2PIC A;  1B13 A;  4KLN A;  1YV1 A;  5C9H A;  2Y0S A;  1A36 A;  4AHX A;  1T9O A;  1RYT A;  7RXN A;  2X0Q A;  2NYA A;  2VUM A;  3U44 A;  2PSM C;  3K5N A;  1EU1 A;  2A68 D;  5GAE c;  1Y1V A;  1H7V A;  2O5J D;  4V19 6;  2JIP A;  1FHM A;  1WQG A;  2XJQ A;  1B2O A;  1WQF A;  2QL0 A;  3KYX A;  1FDO A;  1A31 A;  4JAD A;  4AR4 A;  2N3E A;  3QVD A;  4RXN A;  5GLF A;  3QQ8 A;  3IR7 A;  1LKM A;  1OWB A;  1H5N A;  1ZYR D;  2V0F A;  1E32 A;  2E7Z A;  1LPQ A;  2VK9 A;  1VZI A;  5FTK A;  3HU3 A;  4AHZ A;  3SS2 A;  4AYB A;  3GTK A;  5T5I D;  1NNQ A;  2RDV A;  2LCQ A;  5CQG A;  3ML1 A;  4KDI A;  2R92 A;  4QCL A;  1SMW A;  4AHY A;  1PQF A;  1TMO A;  3QQ7 A;  1IU6 A;  4CS0 A;  2JIM A;  2M6O A;  2B5I D;  2JIQ A;  5JVH 1;  2PVE A;  5FTN A;  1R49 A;  2HR5 A;  2KN9 A;  2JIR A;  1BQ9 A;  3IAY A;  4AI0 A;  2JI3 A;  3A44 A;  1QYB A;  1PQE A;  1LKO A;  3O5A A;  3J7Y 1;  2PVX A;  4OYD B;  1K4S A;  1R0I A;  1R7R A;  4XXB B;  1E18 A;  2PJJ A;  1A35 A;  3PIO 1;  1TWA A;  5C1B A;  1I3Q A;  1TWG A;  1TWF A;  1YK4 A;  4ZN1 B;  2VL6 A;  3MAQ A;  4G6B A;  2NVY A;  2V3B B;  3KYV A;  4L8I A;  3P9A A;  3PWF A;  1EJ9 A;  1R5Z A;  5T5M D;  2B63 A;  2LPJ A;  2C45 A;  1I6V D;  1DX8 A;  3PKI A;  5DYI A;  4KDL A;  1VZG A;  1UHE A;  1TWH A;  2ERS A;  2V0E A;  2J9U B;  5DM7 1;  2F5J A;  1Q16 A;  1OGY A;  1DMR A;  2JA5 A;  3MSU A;  5JVG 1;  3WWL A;  3K5O A;  2XJS A;  3CZB A;  2F4Q A;  2IV2 X;  3QQC E;  2CR8 A;  4AHC A;  3PKJ A;  1IRN A;  5GAG c;  4WFN 1;  2YUJ A;  1IW7 D;  4AOK B;  2GAE A;  2VPW A;  2VPZ A;  4O26 A;  1CZ5 A;  4F3E A;  4KC6 A;  3P8B A;  2R7Z A;  4H3T A;  3M4A A;  2E2H A;  4AR5 A;  4UY8 1;  2M6P A;  1B2J A;  1YK5 A;  2V3V A;  3LPE B;  3K5M A;  1VZH A;  4AZD A;  1SMY D;  1OWC A;  4FGU A;  2GMG A;  2PPT A;  1QCV A;  1BRF A;  4IP8 A;  1SFO A;  2K3Q A;  3LR6 A;  5IY0 A;  2XJR A;  3LNL A;  3ZG6 A;  2ZIX A;  2H12 A;  4Q5G A;  1IU5 A;  5FTM A;  4AAY A;  5B6C A;  1BE7 A;  3DMR A;  2M4V A;  1R0G A;  4TPU A;  2WB1 A;  1TWC A;  4NOK A;  2R4G A;  1YLE A;  5EPP A;  4KO8 A;  8RXN A;  1KQF A;  1RRJ A;  4KOD A;  3HU2 A;  5DYG A;  2BE5 D;  4GA5 A;  3GTJ A;  4U67 1;  2VPX A;  4QIW A;  1SMU A;  5C18 A;  1EK8 A;  3KYU A;  4CEH A;  1ODH A;  2M4Y A;  1G8J A;  1T9Q A;  1R9T A;  1CAD A;  4NOH A;  1B71 A;  1NH3 A;  4KB2 A;  3VPB E;  1E5V A;  3GTM A;  4D7Z B;  1QCS A;  4AR6 A;  1SMM A;  4IP9 A;  1K83 A;  2CKA A;  3CF2 A;  1BFY A;  2PNW A;  4KB4 A;  4FXD A;  1PYU B;  5EIO C;  3PIP 1;  2B9S B;  3TIW A;  1BQ8 A;  2N1D B;  3WVO A;  2CW0 D;  1E61 A;  4C2M A;  1ZRP A;  4FBS A;  4LHN A;  1AA6 A;  2C6A A;  4JAG A;  1YNN D;  3FKI A;  5MFZ A;  2G6G A;  3GTL A;  3OUG A;  1YUX A;  2A6E D;  3PLX B;  1SEU A;  4AI2 A;  2NAP A;  1WLF A;  1T8I A;  2CKC A;  4AR3 A;  1MIU A;  1VC3 B;  2PMZ A;  3CQZ A;  2NYD A;  2XJU A;  3U4Q A;  4AHW A;  3NFP I;  2XJV A;  2X0P A;  1TGO A;  1H0H A;  2JA7 A;  3B08 B;  1RR8 C;  1NXE A;  1IS1 A;  2YU9 A;  1WJV A;  1RDG A;  4JLR C;  4K9F A;  1JYB A;  3HU1 A;  1DMS A;  4KAW X;  4POF A;  2L0Z A;  3SJR A;  5GAD c;  3LF9 A;  5MLC 3;  4DMR A;  1E8J A;  3GTP A;  2MX8 A;  2E2I A;  1C09 A;  1Y69 8;  1Q8I A;  4NOM A;  4GFQ A;  1RWD A;  3K59 A;  3RZ6 A;  2JI1 A;  2PI8 A;  3KYL A;  4B8C D;  3K5L A;  2MX9 A;  4XGH A;  2LPI A;  2K3O A;  5AN9 H;  1TL8 A;  1UHD A;  5JSN B;  4FYD A;  5RXN A;  1HQM D;  5JSB B;  5MFP A;  1FDI A;  4AI3 A;  3GTO A;  2LTH A;  1T9P A;  4LHL A;  1VCX A;  2AQL A;  2XJP A;  3LRD A;  1S30 A;  1R0J A;  2G5D A;  2KKD A;  4D3Y A;  5AI2 A;  3WWN B;  2NVX A;  3QC8 A;  1CR5 A;  4GA6 A;  2JIO A;  2VPY A;  3DU6 A;  3LHP S;  5IZ2 A;  5FTL A;  2Z3R B;  1LKP A;  3K35 A;  4Q5V A;  1S3S A;  2V45 A;  1AW8 B;  5H1S c; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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