2O5JD

Crystal structure of the t. thermophilus rnap polymerase elongation complex with the ntp substrate analog
Total Genus 275
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
275
sequence length
1504
structure length
1264
Chain Sequence
b'KKEVRKVRIALASPEKIRSWSYGEVEKPETINYRTLKPERDGLFDERIFGPIKDYECACGKYKRQRFEGKVCERCGVEVTKSIVRRYRMGHIELATPAAHIWFVKDVPSKIGTLLDLSATELEQVLYFSKYIVLDPKGAILNGVPVEKRQLLTDEEYRELRYGKQETYPLPPGVDALVKDGEEVVKGQELAPGVVSRLDGVALYRFASILVVKARVYPFEDDVEVSTGDRVAPGDVLADGGKVKSDVYGRVEVDLVRNVVRVVESYDIDARMGAEAIQQLLKELDLEALEKELLEEMKHPSRARRAKARKRLEVVRAFLDSGNRPEWMILEAVPVLPPDLRPMVQVDGGRFATSDLNDLYRRLINRNNRLKKLLAQGAPEIIIRNEKRMLQEAVDALLDNGRRGAPVTNPGSDRPLRSLTDILSGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKRMALELFKPFLLKKMEEKGIAPNVKAARRMLERQRDIKDEVWDALEEVIHGKVVLLNRAPTLHRLGIQAFQPVLVEGQSIQLHPLVCEAFNADFDGDQMAVHVPLSSFAQAEARIQMLSAHNLLSPASGEPLAKPSRDIILGLYYITQVRKEKKGAGLEFATPEEALAAHERGEVALNAPIKVAGRETSVGRLKYVFANPDEALLAVAHGIVDLQDVVTVRYMGKRLETSPGRILFARIVAEAVEDEKVAWELIQLDVPQEKNSLKDLVYQAFLRLGMEKTARLLDALKYYGFTFSTTSGITIGIDDAVIPEEKKQYLEEADRKLLQIEQAYEMGFLTDRERYDQILQLWTETTEKVTQAVFKNFEENYPFNPLYVMAQSGARGNPQQIRQLCGLRGLMQKPSGETFEVPVRSSFREGLTVLEYFISSHGARKGGADTALRTADSGYLTRKLVDVTHEIVVREADCGTTNYISVPLFQPDEVTRSLRLRKRADIEAGLYGRVLAREVEVLGVRLEEGRYLSMDDVHLLIKAAEAGEIQEVPVRSPLTCQTRYGVCQKCYGYDLSMARPVSIGEAVGIVAAQSIGEPGTQLTMRTFHTGGVAGAADITQGLPRVIELFEARRPKAKAIDPHQLLEAKGPEAVERYLVEEIQKVYRAQGVKLHDKHIEIVVRQMMKYVEVTDPGDSRLLEGQVLEKWDVEALNERLIAEGKTPVAWKPLLMGVTKSALSTKSWLSAASFQNTTHVLTEAAIAGKKDELIGLKENVILGRLIPAGTGSDFVRFTQVVDQKTLKAIEEARKEAVEA'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords 5'-D(P*CP*CP*CP*TP*GP*TP*CP*TP*GP*GP*CP*GP*TP*TP*CP*GP*CP*GP
publication title Structural basis for substrate loading in bacterial RNA polymerase.
pubmed doi rcsb
molecule tags Transferase/dna-rna hybrid
total genus 275
structure length 1264
sequence length 1504
chains with identical sequence N
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2006-12-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00623 RNA_pol_Rpb1_2 RNA polymerase Rpb1, domain 2
D PF04983 RNA_pol_Rpb1_3 RNA polymerase Rpb1, domain 3
D PF04997 RNA_pol_Rpb1_1 RNA polymerase Rpb1, domain 1
D PF04998 RNA_pol_Rpb1_5 RNA polymerase Rpb1, domain 5
D PF05000 RNA_pol_Rpb1_4 RNA polymerase Rpb1, domain 4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.132.30 Mainly Alpha Orthogonal Bundle Topoisomerase I; Chain A, domain 4 Topoisomerase I; Chain A, domain 4 2o5jD05
1.10.274.100 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 Enzyme I; Chain A, domain 2 2o5jD04
2.20.28.170 Mainly Beta Single Sheet Rubrerythrin, domain 2 Rubrerythrin, domain 2 2o5jD07
2.40.40.70 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 2o5jD03
1TWFA 1WCMA 3GTQA 1I50A 2WB1A 2A69D 1IW7D 2Y0SA 2VUMA 2A6HD 2CW0D 2JA5A 1HQMD 1ZYRD 1TWGA 1Y1VA 2PMZA 4QIWA 1R9TA 3GTMA 3GTKA 2R7ZA 2WAQA 2NVXA 3HKZA 3H0GA 4AYBA 1TWHA 3GTJA 3GTGA 2A6ED 3CQZA 3GTOA 2A68D 2JA7A 1I3QA 1Y1WA 2R92A 2E2IA 1YNND 2B63A 3GTPA 1YNJD 2NVYA 2BE5D 2R93A 1SFOA 3GTLA 2JA6A 2O5JD 1TWCA 1I6VD 1TWAA 1SMYD 3FKIA 2E2HA 4C2MA 2YU9A 1K83A
chains in the Genus database with same CATH superfamily
4AR3A 3S17L 1SMUA 3O5AA 4C2M1 4AR6A 4A3EL 5FTNA 3TM7B 1GE9A 1WQHA 3CF2A 1OA9A 3ZG6A 1T9OA 4E6YA 5C4JL 2WAQP 1G8KA 3K58A 3NZ4A 1ZRPA 2CKAA 2MX8A 4NOKA 2AE0X 2A6ED 2V0EA 5IYDL 2DSXA 3KYVA 2JIQA 3X2PA 1PT1A 5B6CA 2JIPA 2LKMB 5MLC9 3PZAA 2PJHB 1RDGA 2BE5D 4IP8A 3K7AL 5M5XL 1SMYD 4A3DL 3IR5A 3QWZA 2MP0A 3DU5A 3PO3L 1HD5A 1TWFA 4JP7A 3X2OA 3GTQA 4LMOA 1IW7D 5AI2A 2JA5L 2A6HD 4POGA 3HOUL 2MS3A 1PFUA 2XJPA 1TWGA 1B71A 4AHZA 4FYDA 1AA6A 2PVXA 4A3IL 4C5RA 4CEJA 1T6PA 2JI2A 1UHDA 1ZC1A 1S2ZA 3KYUA 2NVTL 5DM71 1PZXA 5MFZA 3K5NA 3PLXB 2NVYA 2Y0NA 2GMGA 2FIPA 1LKOA 3GTKL 1TWAL 4A3LL 3S1RL 1Q8IA 4JADA 1K83L 3SUKA 4Y7NL 1PPYA 1FDIA 4ME3A 1IROA 3M3GA 1LTLA 1QYBA 1W27A 1I50A 4NOHA 4O26A 2WB1P 3PIP1 4FXDA 5IYCL 3LWOB 2V0FA 3JR7A 4AHYA 3WWNB 1OWCA 2NVXA 2VPYA 1RWDA 1YUXA 3HKZA 4JLRC 1BRFA 1WC2A 1RR8C 2X0OA 3M3YL 2M6OA 3SUJA 3IR6A 2Z3QB 1EJ9A 1Y698 3GTPA 4BABA 2CKCA 4AHWA 5IP9L 4Q5GA 2RFKB 1DMRA 2YU9L 4D3YA 3GTKA 3MPSA 5K2ME 2JIRA 3RYGA 4D7ZB 3K5LA 3HU1A 2G5DA 2E2JL 4QIWA 1YK5A 3LWRB 1LKMA 4A3FL 5GM9A 4V196 3S14L 1SMMA 1FDOA 4AYBA 4A93L 1R0JA 3M4OL 3HOZL 5EPPA 2EEOB 1E61A 4IP9A 4AN8A 3PIO1 2LCQA 4V2QA 3GTLA 5DYGA 1Y5IA 4KODA 4CS0A 2V3VA 3I4ML 3LR2A 1IS1A 3RZ6A 4AI0A 4F3EA 4KAWX 1CAAA 2M6PA 3HAXC 2G6GA 1R27A 1SC7A 2C6AA 3HJWB 4FG2A 1R9TA 1EZBA 1R7RA 1H0HA 3H0GL 4H3TA 1RYQA 3K57A 3X2IA 3GTJA 1DMSA 2N3EA 3MAQA 2J9UB 2HR5A 5GLFA 2JA7A 3LWPB 1YNND 5RXNA 4FERA 3LR8A 2JI3A 1PYQA 1E18A 4ZM7A 1TWFL 3KYWA 1R0IA 3GTQL 1PYUB 3TIWA 2JI1A 1YUZA 5JSBB 1R0GA 3K59A 3LRDA 3D30A 5EINC 1TWGL 4LHNA 4FG4A 2ERJA 3MSUA 2JA8L 2R7ZA 4B8CD 1PFVA 1NXEA 1OWBA 3U44A 5IY0A 3H0GA 3QQ7A 1SEUA 1N10A 5IZ2A 3S2HL 1Z92B 4FFTA 3H9BA 4AOKB 2NVYL 3X2LA 1B2OA 3WWLA 4BAAA 4TVMA 1BQ9A 1ODHA 2BH0A 2E7ZA 2O5JD 1E32A 3KYYA 4C3IL 1ZYMA 4AR4A 2L0ZA 1I50L 4AI1A 2APOB 2WB1A 4RV0A 3MQKB 4CRYG 1RDVA 2XJUA 4CEHA 4ENGA 1A36A 1IU6A 3QC8A 2XJTA 2NVXL 4KB4A 3DMRA 5EIOC 4AHXA 4Q5VA 4KDDA 3CZBA 3GTGA 3CQZA 1EZAA 4JAFA 3ENGA 5C44L 1PQFA 4Y52L 2EZAA 3GTPL 4UY81 4FGUA 3K5OA 1QDNA 4BY1L 2K3QA 7RXNA 3B08B 2VK9A 3ML1A 3EZAA 1EH1A 1RB9A 5FTJA 1TMOA 4AONB 3EZEA 2C6BA 5M3ML 3LHPS 2Y0SP 3S1NL 1PFWA 2F5JA 5C18A 2VL6A 2FIOA 1T6JA 1BW4A 2DMRA 5H1Sc 3K5MA 1F4LA 4JJOA 4A3BL 3S1QL 4AR5A 4YWMA 3J7Z1 3GTLL 2V45A 1ISEA 3SS2A 5GLYA 1I6VD 5C4XL 1S24A 4K9FA 2NYDA 3RZTA 5DYIA 3P9AA 3SJRA 4KO8A 1B2JA 2GAEA 2VUMA 1G8JA 5MFPA 4C5UA 2XJVA 1R9TL 3M4AA 2PMZA 1R49A 1BFYA 2AQCA 4AI2A 4A3GL 3GTJL 2K3NA 4AI3A 3QQ8A 3DU6A 2NYAA 4XXBB 4C3JL 2JA7L 2A68D 3S2DL 4KLNA 3LF9A 2LYIA 1YK4A 2LPJA 4JCWA 1LPQA 5JVG1 2R93A 5T5ID 3QVDA 5AI3A 3S15L 4KDLA 5GADc 2VPWA 4L8IA 1QCVA 2B9SB 1VCXA 2PNWA 3IR7A 2PI8A 1WQGA 4X6AL 5FTLA 5JSNB 3X2GA 3GTMA 2R7ZL 2WAQA 1TWHL 2KKDA 4ZN1B 1PQHA 2HWGA 1DD5A 1WQFA 1R5ZA 5M3FL 1QCSA 1VZGA 1V9MA 1FHMA 3FKIL 3H9CA 1TWCA 4A3ML 4BBSL 3IU3I 4C2MA 3H3VM 2XJQA 2B5ID 1WCMA 4C6GA 3H97A 3KYLA 1BW3A 1T9QA 1Y1VL 4BY7L 4CQ5A 2HCZX 3HOYL 1CZ5A 2K2DA 3P2AA 1DVBA 3S1ML 5FTMA 4QIWP 3X2JA 1I6HL 2AYJA 5IP7L 1B13A 3PWFA 3GTGL 1TWHA 1CR5A 4C3HL 2V3BB 3CQZL 3X2NA 3A44A 1VZHA 1CADA 3S16L 2VPXA 3PKIA 1I3QA 1Y1WA 2LTHA 2YUJA 5C3EL 4AZDA 2B63A 1YNJD 1TL8A 2R4GA 2JA6A 3HOWL 2KN9A 3FKIA 2E2HA 4C5SA 4TPUA 6RXNA 1BQ8A 2M4VA 1E5VA 2NAPA 2A69D 4A3JL 2Y0SA 3B0AB 2CW0D 4YWLA 1P7PA 3OUGA 5M5YL 1Y1VA 4GA5A 4GS7D 4JP6A 4OYDB 2AUSB 2C45A 1BE7A 2PJJA 4POFA 3LR6A 5GAEc 2XJRA 1Y4ZA 2X0QA 3GTOA 2R92L 3RZOL 4GFQA 4CRZA 3NFPI 1K4TA 2E2IA 2N1DB 2EZCA 1Q16A 5AN9H 1E60A 1SFOA 5GAHc 3PKJA 1JYBA 1UHEA 1IU5A 1R0FA 5GLXA 2EZBA 2HVYC 4WFN1 3LWVB 1VC3B 3HOVL 5IYBL 5FJ8L 1WJVA 4LHLA 2VUML 1DX8A 4AVRA 1CZ4A 1NXGA 5DM61 1ZYRD 3FDJA 5GAGc 3PL5A 1Y2MA 5FTKA 3KYXA 3QQCE 1MIUA 4U671 4A3KL 2AQLA 3K35A 2JIOA 5T5MD 3IAYA 3X2KA 4QCLA 4BXXL 2QL0A 2ZIXA 2R92A 4JAEA 2R93L 1RRJA 4NOLA 1QQTA 4V2RA 2XJSA 3J7Y1 1OGYA 2IV2X 2YIIA 4DMRA 5MF6A 4JAGA 1H7VA 1PFYA 4CEIA 2JA5A 1KQFA 5H4UA 1S3SA 2Z3RB 3GTML 2F4QA 4AAYA 3RZDL 1C09A 8RXNA 4A3CL 3VPBE 1A31A 3LPEB 1YLEA 4KC6A 3HJYB 3LNLA 2EY4E 1TWCL 1EU1A 1TWAA 5C1BA 5CQGA 1K83A 1IRNA 3WVOA 1H5NA 1WCML 1L8FA 1VZIA 4NOMA 3HOXL 4FBSA 1WLFA 1PQEA 2RDVA 1HQMD 1AW8B 2VPZA 3U4QA 1RYTA 4KB2A 1R0HA 5M5WL 3PO2L 3I4NL 2H12A 2PSMC 1YV1A 2JIMA 1LKPA 2PICA 5MGNA 2MX9A 1T9PA 3HU3A 5FLML 3HKZP 4L48A 2NVQL 3LWQB 5C9HA 1S30A 3SULA 2LPIA 1I3QL 4RXNA 1Y1WL 4JS7A 2B63L 2KQAA 4BBRL 4KDIA 1NNQA 2JA6L 1OA7A 4GA6A 1NH3A 3H99A 2E2HL 2PPTA 2YU9A 4XGHA 1A35A 3SUMA 3HU2A 1KQGA 4EJ3A 1T8IA 3X2HA 2K3OA 2HROA 2CR8A 3X2MA 4D3ZA 2KI8A 2M4YA 2PMZP 1SMWA 2PYAA 4AHCA 2MQAA 1K4SA 2X0PA 1TGOA 3P8BA 4G6BA 1FHHA 2ERSA 1E8JA 3GTOL 4AYBP 1PT0A 1SIWA 2E2IL 2ENGA 2PVEA 1SFOL 4ZN3B 1EK8A 3EZBA 5JVH1 5MLC3
chains in the Genus database with same CATH topology
4AR3A 3O5AA 1SMUA 4AR6A 5FTNA 3TM7B 1GE9A 1WQHA 3CF2A 3ZG6A 1T9OA 4E6YA 1G8KA 3K58A 1ZRPA 2CKAA 2MX8A 4NOKA 2AE0X 2A6ED 2V0EA 2DSXA 3KYVA 2JIQA 1PT1A 5B6CA 2JIPA 2LKMB 5MLC9 3PZAA 2PJHB 1RDGA 2BE5D 4IP8A 1SMYD 3IR5A 3QWZA 3DU5A 1TWFA 3GTQA 4LMOA 1IW7D 5AI2A 4POGA 2A6HD 2MS3A 2XJPA 1TWGA 1B71A 4AHZA 4FYDA 1AA6A 2PVXA 4CEJA 1ZC1A 2JI2A 1UHDA 1S2ZA 3KYUA 5DM71 5MFZA 3K5NA 3PLXB 2NVYA 2Y0NA 2GMGA 2FIPA 1LKOA 1Q8IA 4JADA 1PPYA 1FDIA 4ME3A 1IROA 1LTLA 1QYBA 1I50A 4NOHA 4O26A 3PIP1 4FXDA 2V0FA 4AHYA 3WWNB 1OWCA 2NVXA 2VPYA 1RWDA 1YUXA 3HKZA 4JLRC 1BRFA 1RR8C 2X0OA 2M6OA 3IR6A 2Z3QB 1EJ9A 1Y698 3GTPA 4AHWA 2CKCA 4Q5GA 1DMRA 4D3YA 3GTKA 3MPSA 5K2ME 2JIRA 3RYGA 4D7ZB 3K5LA 3HU1A 2G5DA 4QIWA 1YK5A 1LKMA 4V196 1SMMA 1FDOA 4AYBA 1R0JA 5EPPA 2EEOB 1E61A 4IP9A 4AN8A 3PIO1 2LCQA 5DYGA 3GTLA 1Y5IA 4KODA 4CS0A 2V3VA 3LR2A 1IS1A 3RZ6A 4AI0A 4F3EA 4KAWX 1CAAA 2M6PA 2G6GA 1R27A 1SC7A 2C6AA 1R9TA 1R7RA 1H0HA 4H3TA 1RYQA 3K57A 3GTJA 1DMSA 2N3EA 3MAQA 2J9UB 2HR5A 5GLFA 2JA7A 1YNND 5RXNA 3LR8A 2JI3A 1PYQA 1E18A 3KYWA 1R0IA 1PYUB 3TIWA 2JI1A 1YUZA 5JSBB 1R0GA 3K59A 3LRDA 5EINC 4LHNA 2ERJA 3MSUA 2R7ZA 4B8CD 1NXEA 1OWBA 3U44A 5IY0A 3H0GA 3QQ7A 1SEUA 5IZ2A 1Z92B 4AOKB 1B2OA 3WWLA 4TVMA 1BQ9A 1ODHA 2E7ZA 2O5JD 1E32A 3KYYA 4AR4A 2L0ZA 4AI1A 2WB1A 4RV0A 4CRYG 1RDVA 2XJUA 4CEHA 1A36A 1IU6A 3QC8A 2XJTA 4KB4A 3DMRA 5EIOC 4AHXA 4Q5VA 4KDDA 3CZBA 3GTGA 3CQZA 4JAFA 1PQFA 4UY81 4FGUA 3K5OA 1QDNA 2K3QA 7RXNA 3B08B 2VK9A 3ML1A 1EH1A 1RB9A 5FTJA 1TMOA 4AONB 2C6BA 3LHPS 2F5JA 5C18A 2VL6A 2FIOA 2DMRA 5H1Sc 3K5MA 4AR5A 4YWMA 3J7Z1 2V45A 1ISEA 3SS2A 1I6VD 1S24A 4K9FA 2NYDA 3RZTA 5DYIA 3P9AA 3SJRA 4KO8A 1B2JA 2GAEA 2VUMA 1G8JA 5MFPA 2XJVA 3M4AA 2PMZA 1R49A 1BFYA 4AI2A 2K3NA 4AI3A 3QQ8A 3DU6A 2NYAA 4XXBB 2A68D 4KLNA 3LF9A 2LYIA 1YK4A 2LPJA 1LPQA 5JVG1 2R93A 5T5ID 3QVDA 5AI3A 4KDLA 5GADc 2VPWA 4L8IA 1QCVA 2B9SB 1VCXA 2PNWA 3IR7A 2PI8A 1WQGA 5FTLA 5JSNB 3GTMA 2WAQA 2KKDA 4ZN1B 1PQHA 1DD5A 1WQFA 1R5ZA 1QCSA 1VZGA 1V9MA 1FHMA 1TWCA 3IU3I 4C2MA 2XJQA 2B5ID 1WCMA 3KYLA 1T9QA 1CZ5A 2K2DA 3P2AA 1DVBA 5FTMA 2AYJA 1B13A 3PWFA 1TWHA 1CR5A 2V3BB 3A44A 1VZHA 1CADA 2VPXA 3PKIA 1I3QA 1Y1WA 2LTHA 2YUJA 4AZDA 2B63A 1YNJD 1TL8A 2R4GA 2JA6A 2KN9A 3FKIA 2E2HA 4TPUA 6RXNA 1BQ8A 2M4VA 1E5VA 2NAPA 2A69D 2Y0SA 3B0AB 2CW0D 4YWLA 3OUGA 1Y1VA 4GA5A 4GS7D 4OYDB 2C45A 1BE7A 2PJJA 4POFA 3LR6A 5GAEc 2XJRA 1Y4ZA 2X0QA 3GTOA 4GFQA 4CRZA 3NFPI 1K4TA 2E2IA 2N1DB 1Q16A 5AN9H 1E60A 1SFOA 5GAHc 3PKJA 1JYBA 1UHEA 1IU5A 1R0FA 4WFN1 1VC3B 1WJVA 4LHLA 1DX8A 1CZ4A 1NXGA 5DM61 1ZYRD 5GAGc 5FTKA 3KYXA 3QQCE 1MIUA 4U671 2AQLA 3K35A 2JIOA 5T5MD 3IAYA 4QCLA 2QL0A 2ZIXA 2R92A 4JAEA 1RRJA 4NOLA 2XJSA 3J7Y1 1OGYA 2IV2X 4DMRA 5MF6A 4JAGA 1H7VA 4CEIA 2JA5A 1KQFA 1S3SA 2Z3RB 2F4QA 4AAYA 1C09A 8RXNA 3VPBE 1A31A 3LPEB 1YLEA 4KC6A 3LNLA 1EU1A 1TWAA 5C1BA 5CQGA 1K83A 1IRNA 3WVOA 1H5NA 1VZIA 4NOMA 4FBSA 1WLFA 1PQEA 2RDVA 1HQMD 1AW8B 2VPZA 3U4QA 1RYTA 4KB2A 1R0HA 2H12A 2PSMC 1YV1A 2JIMA 1LKPA 2PICA 5MGNA 2MX9A 1T9PA 3HU3A 5C9HA 1S30A 2LPIA 4RXNA 4KDIA 1NNQA 4GA6A 1NH3A 2PPTA 2YU9A 4XGHA 1A35A 3HU2A 1KQGA 4EJ3A 1T8IA 2K3OA 2CR8A 4D3ZA 2KI8A 2M4YA 1SMWA 2PYAA 4AHCA 2MQAA 1K4SA 2X0PA 1TGOA 3P8BA 4G6BA 1FHHA 2ERSA 1E8JA 1PT0A 1SIWA 2PVEA 4ZN3B 1EK8A 5JVH1 5MLC3
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TWF A;  1WCM A;  3GTQ A;  1I50 A;  2WB1 A;  2A69 D;  1IW7 D;  2Y0S A;  2VUM A;  2A6H D;  2CW0 D;  2JA5 A;  1HQM D;  1ZYR D;  1TWG A;  1Y1V A;  2PMZ A;  4QIW A;  1R9T A;  3GTM A;  3GTK A;  2R7Z A;  2WAQ A;  2NVX A;  3HKZ A;  3H0G A;  4AYB A;  1TWH A;  3GTJ A;  3GTG A;  2A6E D;  3CQZ A;  3GTO A;  2A68 D;  2JA7 A;  1I3Q A;  1Y1W A;  2R92 A;  2E2I A;  1YNN D;  2B63 A;  3GTP A;  1YNJ D;  2NVY A;  2BE5 D;  2R93 A;  1SFO A;  3GTL A;  2JA6 A;  2O5J D;  1TWC A;  1I6V D;  1TWA A;  1SMY D;  3FKI A;  2E2H A;  4C2M A;  2YU9 A;  1K83 A; 
#chains in the Genus database with same CATH topology
 4AR3 A;  3S17 L;  1SMU A;  3O5A A;  4C2M 1;  4AR6 A;  4A3E L;  5FTN A;  3TM7 B;  1GE9 A;  1WQH A;  3CF2 A;  1OA9 A;  3ZG6 A;  1T9O A;  4E6Y A;  5C4J L;  2WAQ P;  1G8K A;  3K58 A;  3NZ4 A;  1ZRP A;  2CKA A;  2MX8 A;  4NOK A;  2AE0 X;  2A6E D;  2V0E A;  5IYD L;  2DSX A;  3KYV A;  2JIQ A;  3X2P A;  1PT1 A;  5B6C A;  2JIP A;  2LKM B;  5MLC 9;  3PZA A;  2PJH B;  1RDG A;  2BE5 D;  4IP8 A;  3K7A L;  5M5X L;  1SMY D;  4A3D L;  3IR5 A;  3QWZ A;  2MP0 A;  3DU5 A;  3PO3 L;  1HD5 A;  1TWF A;  4JP7 A;  3X2O A;  3GTQ A;  4LMO A;  1IW7 D;  5AI2 A;  2JA5 L;  2A6H D;  4POG A;  3HOU L;  2MS3 A;  1PFU A;  2XJP A;  1TWG A;  1B71 A;  4AHZ A;  4FYD A;  1AA6 A;  2PVX A;  4A3I L;  4C5R A;  4CEJ A;  1T6P A;  2JI2 A;  1UHD A;  1ZC1 A;  1S2Z A;  3KYU A;  2NVT L;  5DM7 1;  1PZX A;  5MFZ A;  3K5N A;  3PLX B;  2NVY A;  2Y0N A;  2GMG A;  2FIP A;  1LKO A;  3GTK L;  1TWA L;  4A3L L;  3S1R L;  1Q8I A;  4JAD A;  1K83 L;  3SUK A;  4Y7N L;  1PPY A;  1FDI A;  4ME3 A;  1IRO A;  3M3G A;  1LTL A;  1QYB A;  1W27 A;  1I50 A;  4NOH A;  4O26 A;  2WB1 P;  3PIP 1;  4FXD A;  5IYC L;  3LWO B;  2V0F A;  3JR7 A;  4AHY A;  3WWN B;  1OWC A;  2NVX A;  2VPY A;  1RWD A;  1YUX A;  3HKZ A;  4JLR C;  1BRF A;  1WC2 A;  1RR8 C;  2X0O A;  3M3Y L;  2M6O A;  3SUJ A;  3IR6 A;  2Z3Q B;  1EJ9 A;  1Y69 8;  3GTP A;  4BAB A;  2CKC A;  4AHW A;  5IP9 L;  4Q5G A;  2RFK B;  1DMR A;  2YU9 L;  4D3Y A;  3GTK A;  3MPS A;  5K2M E;  2JIR A;  3RYG A;  4D7Z B;  3K5L A;  3HU1 A;  2G5D A;  2E2J L;  4QIW A;  1YK5 A;  3LWR B;  1LKM A;  4A3F L;  5GM9 A;  4V19 6;  3S14 L;  1SMM A;  1FDO A;  4AYB A;  4A93 L;  1R0J A;  3M4O L;  3HOZ L;  5EPP A;  2EEO B;  1E61 A;  4IP9 A;  4AN8 A;  3PIO 1;  2LCQ A;  4V2Q A;  3GTL A;  5DYG A;  1Y5I A;  4KOD A;  4CS0 A;  2V3V A;  3I4M L;  3LR2 A;  1IS1 A;  3RZ6 A;  4AI0 A;  4F3E A;  4KAW X;  1CAA A;  2M6P A;  3HAX C;  2G6G A;  1R27 A;  1SC7 A;  2C6A A;  3HJW B;  4FG2 A;  1R9T A;  1EZB A;  1R7R A;  1H0H A;  3H0G L;  4H3T A;  1RYQ A;  3K57 A;  3X2I A;  3GTJ A;  1DMS A;  2N3E A;  3MAQ A;  2J9U B;  2HR5 A;  5GLF A;  2JA7 A;  3LWP B;  1YNN D;  5RXN A;  4FER A;  3LR8 A;  2JI3 A;  1PYQ A;  1E18 A;  4ZM7 A;  1TWF L;  3KYW A;  1R0I A;  3GTQ L;  1PYU B;  3TIW A;  2JI1 A;  1YUZ A;  5JSB B;  1R0G A;  3K59 A;  3LRD A;  3D30 A;  5EIN C;  1TWG L;  4LHN A;  4FG4 A;  2ERJ A;  3MSU A;  2JA8 L;  2R7Z A;  4B8C D;  1PFV A;  1NXE A;  1OWB A;  3U44 A;  5IY0 A;  3H0G A;  3QQ7 A;  1SEU A;  1N10 A;  5IZ2 A;  3S2H L;  1Z92 B;  4FFT A;  3H9B A;  4AOK B;  2NVY L;  3X2L A;  1B2O A;  3WWL A;  4BAA A;  4TVM A;  1BQ9 A;  1ODH A;  2BH0 A;  2E7Z A;  2O5J D;  1E32 A;  3KYY A;  4C3I L;  1ZYM A;  4AR4 A;  2L0Z A;  1I50 L;  4AI1 A;  2APO B;  2WB1 A;  4RV0 A;  3MQK B;  4CRY G;  1RDV A;  2XJU A;  4CEH A;  4ENG A;  1A36 A;  1IU6 A;  3QC8 A;  2XJT A;  2NVX L;  4KB4 A;  3DMR A;  5EIO C;  4AHX A;  4Q5V A;  4KDD A;  3CZB A;  3GTG A;  3CQZ A;  1EZA A;  4JAF A;  3ENG A;  5C44 L;  1PQF A;  4Y52 L;  2EZA A;  3GTP L;  4UY8 1;  4FGU A;  3K5O A;  1QDN A;  4BY1 L;  2K3Q A;  7RXN A;  3B08 B;  2VK9 A;  3ML1 A;  3EZA A;  1EH1 A;  1RB9 A;  5FTJ A;  1TMO A;  4AON B;  3EZE A;  2C6B A;  5M3M L;  3LHP S;  2Y0S P;  3S1N L;  1PFW A;  2F5J A;  5C18 A;  2VL6 A;  2FIO A;  1T6J A;  1BW4 A;  2DMR A;  5H1S c;  3K5M A;  1F4L A;  4JJO A;  4A3B L;  3S1Q L;  4AR5 A;  4YWM A;  3J7Z 1;  3GTL L;  2V45 A;  1ISE A;  3SS2 A;  5GLY A;  1I6V D;  5C4X L;  1S24 A;  4K9F A;  2NYD A;  3RZT A;  5DYI A;  3P9A A;  3SJR A;  4KO8 A;  1B2J A;  2GAE A;  2VUM A;  1G8J A;  5MFP A;  4C5U A;  2XJV A;  1R9T L;  3M4A A;  2PMZ A;  1R49 A;  1BFY A;  2AQC A;  4AI2 A;  4A3G L;  3GTJ L;  2K3N A;  4AI3 A;  3QQ8 A;  3DU6 A;  2NYA A;  4XXB B;  4C3J L;  2JA7 L;  2A68 D;  3S2D L;  4KLN A;  3LF9 A;  2LYI A;  1YK4 A;  2LPJ A;  4JCW A;  1LPQ A;  5JVG 1;  2R93 A;  5T5I D;  3QVD A;  5AI3 A;  3S15 L;  4KDL A;  5GAD c;  2VPW A;  4L8I A;  1QCV A;  2B9S B;  1VCX A;  2PNW A;  3IR7 A;  2PI8 A;  1WQG A;  4X6A L;  5FTL A;  5JSN B;  3X2G A;  3GTM A;  2R7Z L;  2WAQ A;  1TWH L;  2KKD A;  4ZN1 B;  1PQH A;  2HWG A;  1DD5 A;  1WQF A;  1R5Z A;  5M3F L;  1QCS A;  1VZG A;  1V9M A;  1FHM A;  3FKI L;  3H9C A;  1TWC A;  4A3M L;  4BBS L;  3IU3 I;  4C2M A;  3H3V M;  2XJQ A;  2B5I D;  1WCM A;  4C6G A;  3H97 A;  3KYL A;  1BW3 A;  1T9Q A;  1Y1V L;  4BY7 L;  4CQ5 A;  2HCZ X;  3HOY L;  1CZ5 A;  2K2D A;  3P2A A;  1DVB A;  3S1M L;  5FTM A;  4QIW P;  3X2J A;  1I6H L;  2AYJ A;  5IP7 L;  1B13 A;  3PWF A;  3GTG L;  1TWH A;  1CR5 A;  4C3H L;  2V3B B;  3CQZ L;  3X2N A;  3A44 A;  1VZH A;  1CAD A;  3S16 L;  2VPX A;  3PKI A;  1I3Q A;  1Y1W A;  2LTH A;  2YUJ A;  5C3E L;  4AZD A;  2B63 A;  1YNJ D;  1TL8 A;  2R4G A;  2JA6 A;  3HOW L;  2KN9 A;  3FKI A;  2E2H A;  4C5S A;  4TPU A;  6RXN A;  1BQ8 A;  2M4V A;  1E5V A;  2NAP A;  2A69 D;  4A3J L;  2Y0S A;  3B0A B;  2CW0 D;  4YWL A;  1P7P A;  3OUG A;  5M5Y L;  1Y1V A;  4GA5 A;  4GS7 D;  4JP6 A;  4OYD B;  2AUS B;  2C45 A;  1BE7 A;  2PJJ A;  4POF A;  3LR6 A;  5GAE c;  2XJR A;  1Y4Z A;  2X0Q A;  3GTO A;  2R92 L;  3RZO L;  4GFQ A;  4CRZ A;  3NFP I;  1K4T A;  2E2I A;  2N1D B;  2EZC A;  1Q16 A;  5AN9 H;  1E60 A;  1SFO A;  5GAH c;  3PKJ A;  1JYB A;  1UHE A;  1IU5 A;  1R0F A;  5GLX A;  2EZB A;  2HVY C;  4WFN 1;  3LWV B;  1VC3 B;  3HOV L;  5IYB L;  5FJ8 L;  1WJV A;  4LHL A;  2VUM L;  1DX8 A;  4AVR A;  1CZ4 A;  1NXG A;  5DM6 1;  1ZYR D;  3FDJ A;  5GAG c;  3PL5 A;  1Y2M A;  5FTK A;  3KYX A;  3QQC E;  1MIU A;  4U67 1;  4A3K L;  2AQL A;  3K35 A;  2JIO A;  5T5M D;  3IAY A;  3X2K A;  4QCL A;  4BXX L;  2QL0 A;  2ZIX A;  2R92 A;  4JAE A;  2R93 L;  1RRJ A;  4NOL A;  1QQT A;  4V2R A;  2XJS A;  3J7Y 1;  1OGY A;  2IV2 X;  2YII A;  4DMR A;  5MF6 A;  4JAG A;  1H7V A;  1PFY A;  4CEI A;  2JA5 A;  1KQF A;  5H4U A;  1S3S A;  2Z3R B;  3GTM L;  2F4Q A;  4AAY A;  3RZD L;  1C09 A;  8RXN A;  4A3C L;  3VPB E;  1A31 A;  3LPE B;  1YLE A;  4KC6 A;  3HJY B;  3LNL A;  2EY4 E;  1TWC L;  1EU1 A;  1TWA A;  5C1B A;  5CQG A;  1K83 A;  1IRN A;  3WVO A;  1H5N A;  1WCM L;  1L8F A;  1VZI A;  4NOM A;  3HOX L;  4FBS A;  1WLF A;  1PQE A;  2RDV A;  1HQM D;  1AW8 B;  2VPZ A;  3U4Q A;  1RYT A;  4KB2 A;  1R0H A;  5M5W L;  3PO2 L;  3I4N L;  2H12 A;  2PSM C;  1YV1 A;  2JIM A;  1LKP A;  2PIC A;  5MGN A;  2MX9 A;  1T9P A;  3HU3 A;  5FLM L;  3HKZ P;  4L48 A;  2NVQ L;  3LWQ B;  5C9H A;  1S30 A;  3SUL A;  2LPI A;  1I3Q L;  4RXN A;  1Y1W L;  4JS7 A;  2B63 L;  2KQA A;  4BBR L;  4KDI A;  1NNQ A;  2JA6 L;  1OA7 A;  4GA6 A;  1NH3 A;  3H99 A;  2E2H L;  2PPT A;  2YU9 A;  4XGH A;  1A35 A;  3SUM A;  3HU2 A;  1KQG A;  4EJ3 A;  1T8I A;  3X2H A;  2K3O A;  2HRO A;  2CR8 A;  3X2M A;  4D3Z A;  2KI8 A;  2M4Y A;  2PMZ P;  1SMW A;  2PYA A;  4AHC A;  2MQA A;  1K4S A;  2X0P A;  1TGO A;  3P8B A;  4G6B A;  1FHH A;  2ERS A;  1E8J A;  3GTO L;  4AYB P;  1PT0 A;  1SIW A;  2E2I L;  2ENG A;  2PVE A;  1SFO L;  4ZN3 B;  1EK8 A;  3EZB A;  5JVH 1;  5MLC 3; 
#chains in the Genus database with same CATH homology
 4AR3 A;  3O5A A;  1SMU A;  4AR6 A;  5FTN A;  3TM7 B;  1GE9 A;  1WQH A;  3CF2 A;  3ZG6 A;  1T9O A;  4E6Y A;  1G8K A;  3K58 A;  1ZRP A;  2CKA A;  2MX8 A;  4NOK A;  2AE0 X;  2A6E D;  2V0E A;  2DSX A;  3KYV A;  2JIQ A;  1PT1 A;  5B6C A;  2JIP A;  2LKM B;  5MLC 9;  3PZA A;  2PJH B;  1RDG A;  2BE5 D;  4IP8 A;  1SMY D;  3IR5 A;  3QWZ A;  3DU5 A;  1TWF A;  3GTQ A;  4LMO A;  1IW7 D;  5AI2 A;  4POG A;  2A6H D;  2MS3 A;  2XJP A;  1TWG A;  1B71 A;  4AHZ A;  4FYD A;  1AA6 A;  2PVX A;  4CEJ A;  1ZC1 A;  2JI2 A;  1UHD A;  1S2Z A;  3KYU A;  5DM7 1;  5MFZ A;  3K5N A;  3PLX B;  2NVY A;  2Y0N A;  2GMG A;  2FIP A;  1LKO A;  1Q8I A;  4JAD A;  1PPY A;  1FDI A;  4ME3 A;  1IRO A;  1LTL A;  1QYB A;  1I50 A;  4NOH A;  4O26 A;  3PIP 1;  4FXD A;  2V0F A;  4AHY A;  3WWN B;  1OWC A;  2NVX A;  2VPY A;  1RWD A;  1YUX A;  3HKZ A;  4JLR C;  1BRF A;  1RR8 C;  2X0O A;  2M6O A;  3IR6 A;  2Z3Q B;  1EJ9 A;  1Y69 8;  3GTP A;  4AHW A;  2CKC A;  4Q5G A;  1DMR A;  4D3Y A;  3GTK A;  3MPS A;  5K2M E;  2JIR A;  3RYG A;  4D7Z B;  3K5L A;  3HU1 A;  2G5D A;  4QIW A;  1YK5 A;  1LKM A;  4V19 6;  1SMM A;  1FDO A;  4AYB A;  1R0J A;  5EPP A;  2EEO B;  1E61 A;  4IP9 A;  4AN8 A;  3PIO 1;  2LCQ A;  5DYG A;  3GTL A;  1Y5I A;  4KOD A;  4CS0 A;  2V3V A;  3LR2 A;  1IS1 A;  3RZ6 A;  4AI0 A;  4F3E A;  4KAW X;  1CAA A;  2M6P A;  2G6G A;  1R27 A;  1SC7 A;  2C6A A;  1R9T A;  1R7R A;  1H0H A;  4H3T A;  1RYQ A;  3K57 A;  3GTJ A;  1DMS A;  2N3E A;  3MAQ A;  2J9U B;  2HR5 A;  5GLF A;  2JA7 A;  1YNN D;  5RXN A;  3LR8 A;  2JI3 A;  1PYQ A;  1E18 A;  3KYW A;  1R0I A;  1PYU B;  3TIW A;  2JI1 A;  1YUZ A;  5JSB B;  1R0G A;  3K59 A;  3LRD A;  5EIN C;  4LHN A;  2ERJ A;  3MSU A;  2R7Z A;  4B8C D;  1NXE A;  1OWB A;  3U44 A;  5IY0 A;  3H0G A;  3QQ7 A;  1SEU A;  5IZ2 A;  1Z92 B;  4AOK B;  1B2O A;  3WWL A;  4TVM A;  1BQ9 A;  1ODH A;  2E7Z A;  2O5J D;  1E32 A;  3KYY A;  4AR4 A;  2L0Z A;  4AI1 A;  2WB1 A;  4RV0 A;  4CRY G;  1RDV A;  2XJU A;  4CEH A;  1A36 A;  1IU6 A;  3QC8 A;  2XJT A;  4KB4 A;  3DMR A;  5EIO C;  4AHX A;  4Q5V A;  4KDD A;  3CZB A;  3GTG A;  3CQZ A;  4JAF A;  1PQF A;  4UY8 1;  4FGU A;  3K5O A;  1QDN A;  2K3Q A;  7RXN A;  3B08 B;  2VK9 A;  3ML1 A;  1EH1 A;  1RB9 A;  5FTJ A;  1TMO A;  4AON B;  2C6B A;  3LHP S;  2F5J A;  5C18 A;  2VL6 A;  2FIO A;  2DMR A;  5H1S c;  3K5M A;  4AR5 A;  4YWM A;  3J7Z 1;  2V45 A;  1ISE A;  3SS2 A;  1I6V D;  1S24 A;  4K9F A;  2NYD A;  3RZT A;  5DYI A;  3P9A A;  3SJR A;  4KO8 A;  1B2J A;  2GAE A;  2VUM A;  1G8J A;  5MFP A;  2XJV A;  3M4A A;  2PMZ A;  1R49 A;  1BFY A;  4AI2 A;  2K3N A;  4AI3 A;  3QQ8 A;  3DU6 A;  2NYA A;  4XXB B;  2A68 D;  4KLN A;  3LF9 A;  2LYI A;  1YK4 A;  2LPJ A;  1LPQ A;  5JVG 1;  2R93 A;  5T5I D;  3QVD A;  5AI3 A;  4KDL A;  5GAD c;  2VPW A;  4L8I A;  1QCV A;  2B9S B;  1VCX A;  2PNW A;  3IR7 A;  2PI8 A;  1WQG A;  5FTL A;  5JSN B;  3GTM A;  2WAQ A;  2KKD A;  4ZN1 B;  1PQH A;  1DD5 A;  1WQF A;  1R5Z A;  1QCS A;  1VZG A;  1V9M A;  1FHM A;  1TWC A;  3IU3 I;  4C2M A;  2XJQ A;  2B5I D;  1WCM A;  3KYL A;  1T9Q A;  1CZ5 A;  2K2D A;  3P2A A;  1DVB A;  5FTM A;  2AYJ A;  1B13 A;  3PWF A;  1TWH A;  1CR5 A;  2V3B B;  3A44 A;  1VZH A;  1CAD A;  2VPX A;  3PKI A;  1I3Q A;  1Y1W A;  2LTH A;  2YUJ A;  4AZD A;  2B63 A;  1YNJ D;  1TL8 A;  2R4G A;  2JA6 A;  2KN9 A;  3FKI A;  2E2H A;  4TPU A;  6RXN A;  1BQ8 A;  2M4V A;  1E5V A;  2NAP A;  2A69 D;  2Y0S A;  3B0A B;  2CW0 D;  4YWL A;  3OUG A;  1Y1V A;  4GA5 A;  4GS7 D;  4OYD B;  2C45 A;  1BE7 A;  2PJJ A;  4POF A;  3LR6 A;  5GAE c;  2XJR A;  1Y4Z A;  2X0Q A;  3GTO A;  4GFQ A;  4CRZ A;  3NFP I;  1K4T A;  2E2I A;  2N1D B;  1Q16 A;  5AN9 H;  1E60 A;  1SFO A;  5GAH c;  3PKJ A;  1JYB A;  1UHE A;  1IU5 A;  1R0F A;  4WFN 1;  1VC3 B;  1WJV A;  4LHL A;  1DX8 A;  1CZ4 A;  1NXG A;  5DM6 1;  1ZYR D;  5GAG c;  5FTK A;  3KYX A;  3QQC E;  1MIU A;  4U67 1;  2AQL A;  3K35 A;  2JIO A;  5T5M D;  3IAY A;  4QCL A;  2QL0 A;  2ZIX A;  2R92 A;  4JAE A;  1RRJ A;  4NOL A;  2XJS A;  3J7Y 1;  1OGY A;  2IV2 X;  4DMR A;  5MF6 A;  4JAG A;  1H7V A;  4CEI A;  2JA5 A;  1KQF A;  1S3S A;  2Z3R B;  2F4Q A;  4AAY A;  1C09 A;  8RXN A;  3VPB E;  1A31 A;  3LPE B;  1YLE A;  4KC6 A;  3LNL A;  1EU1 A;  1TWA A;  5C1B A;  5CQG A;  1K83 A;  1IRN A;  3WVO A;  1H5N A;  1VZI A;  4NOM A;  4FBS A;  1WLF A;  1PQE A;  2RDV A;  1HQM D;  1AW8 B;  2VPZ A;  3U4Q A;  1RYT A;  4KB2 A;  1R0H A;  2H12 A;  2PSM C;  1YV1 A;  2JIM A;  1LKP A;  2PIC A;  5MGN A;  2MX9 A;  1T9P A;  3HU3 A;  5C9H A;  1S30 A;  2LPI A;  4RXN A;  4KDI A;  1NNQ A;  4GA6 A;  1NH3 A;  2PPT A;  2YU9 A;  4XGH A;  1A35 A;  3HU2 A;  1KQG A;  4EJ3 A;  1T8I A;  2K3O A;  2CR8 A;  4D3Z A;  2KI8 A;  2M4Y A;  1SMW A;  2PYA A;  4AHC A;  2MQA A;  1K4S A;  2X0P A;  1TGO A;  3P8B A;  4G6B A;  1FHH A;  2ERS A;  1E8J A;  1PT0 A;  1SIW A;  2PVE A;  4ZN3 B;  1EK8 A;  5JVH 1;  5MLC 3; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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