2O7BA

Tyrosine ammonia-lyase from rhodobacter sphaeroides, complexed with coumarate
Total Genus 194
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
194
sequence length
515
structure length
514
Chain Sequence
PKPAVELDRHIDLDQAHAVASGGARIVLAPPARDRCRASEARLGAVIREARHVYGLTTGFGPLANRLISGENVRTLQANLVHHLASGVGPVLDWTTARAMVLARLVSIAQGASGASEGTIARLIDLLNSELAPAVPSRGTVGDLTPLAHMVLCLQGRGDFLDRDGTRLDGAEGLRRGRLQPLDLSHRDALALVNGTSAMTGIALVNAHACRHLGNWAVALTALLAECLRGRTEAWAAALSDLRPHPGQKDAAARLRARVDGSARVVRHVIAERRLDAGDIGTEPEAGQDAYSLRCAPQVLGAGFDTLAWHDRVLTIELNAVTDNPVFPPDGSVPALHGGNFMGQHVALTSDALATAVTVLAGLAERQIARLTDERLNRGLPPFLHRGPAGLNSGFMGAQVTATALLAEMRATGPASIHSISTNAANQDVVSLGTIAARLCREKIDRWAEILAILALCLAQAAELRCGSGLDGVSPAGKKLVQALREQFPPLETDRPLGQEIAALATHLLQQSPV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases.
pubmed doi rcsb
source organism Rhodobacter sphaeroides
molecule tags Lyase
molecule keywords Putative histidine ammonia-lyase
total genus 194
structure length 514
sequence length 515
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 4.3.1.23: Tyrosine ammonia-lyase.
pdb deposition date 2006-12-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 2o7bA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2o7bA02
2O6YA 3OCFA 1GK3A 3NZ4A 3CZOA 2PFMA 1DOFA 1HY0A 4EEIA 5EYVA 4C5UA 4ADLA 1EB4A 2O7EA 1TJVA 2NYNA 3R6VA 4ADMA 2O7DA 5F91A 2FUSA 2J91A 1B8FA 2PTSA 1FUOA 1C3CA 1FUPA 1RE5A 1TJ7A 4V2QA 2E9FA 4C5SA 5EYTA 1Y2MA 3E04A 2O78A 4FFXA 1YFEA 2X75A 1GKMA 1DCNA 4CQ5A 2QVEA 2RJRA 3RD8A 1YISA 4APAA 3TV2A 2NYFA 2O7BA 2RJSA 3BHGA 1I0AA 1FUQA 2VD6A 4BAAA 1VDKA 1GKJA 3QBPA 1J3UA 1C3UA 2QGAB 4HGVA 4MX2A 4V2RA 1TJWA 1U15A 5F92A 1U16A 1TJUA 1K62A 5HW2A 1GK2A 3KDYA 3KDZA 1KQ7A 1YFMA 4BABA 1XWOA 4APBA 1T6JA 2O7FA 3UNVA 1AUWA 1T6PA 3OCEA 1FURA 1K7WA 1Q5NA 1W27A 4NLEA 4FLCA 3GTDA 2YIIA 2HVGA 1JSWA 4C5RA 4NSLA 3R6YA 3C8TA 3RRPA 2PTQA 3NO9A 3R6QA 4C6GA 2PTRA 3GZHA 4EFCA 5D6BA 2OHYA 1HY1A
chains in the Genus database with same CATH superfamily
2FELA 2O6YA 3OCFA 1GK3A 3NZ4A 4WNLA 3CZOA 2PFMA 1DOFA 1HY0A 4EEIA 1XMDA 2FENA 5EYVA 4C5UA 4ADLA 1EB4A 2O7EA 1TJVA 2NYNA 3R6VA 4ADMA 2O7DA 5F91A 1XL8A 4A15A 2FUSA 2J91A 5M0IA 1B8FA 2PTSA 1FUOA 1C3CA 1FUPA 1RE5A 1TJ7A 4V2QA 2E9FA 4C5SA 5EYTA 1Y2MA 3E04A 2O78A 4FFXA 1YFEA 2X75A 1GKMA 1DCNA 4CQ5A 2QVEA 2RJRA 3RD8A 1YISA 4APAA 3TV2A 2NYFA 2O7BA 2RJSA 3BHGA 1I0AA 1FUQA 2VD6A 4BAAA 1VDKA 1GKJA 3QBPA 2VSFA 1J3UA 3CRVA 1C3UA 2QGAB 4HGVA 4MX2A 4V2RA 1TJWA 1XL7A 1U15A 5F92A 1U16A 5M0JA 1TJUA 1K62A 5HW2A 1GK2A 3KDYA 1XMCA 3KDZA 1KQ7A 2VL7A 1YFMA 4BABA 1XWOA 4APBA 1T6JA 2O7FA 3UNVA 1AUWA 1T6PA 3OCEA 5H8WA 1FURA 1K7WA 1Q5NA 1W27A 4NLEA 1XLYA 4FLCA 3GTDA 2YIIA 2HVGA 1JSWA 4C5RA 4NSLA 3R6YA 3C8TA 3RRPA 2PTQA 3NO9A 3R6QA 3CRW1 4C6GA 2PTRA 3GZHA 4EFCA 5D6BA 2OHYA 1HY1A
chains in the Genus database with same CATH topology
2O6YA 3OCFA 1GK3A 3NZ4A 3CZOA 2PFMA 1DOFA 1HY0A 4EEIA 5EYVA 4C5UA 4ADLA 1EB4A 2O7EA 1TJVA 2NYNA 3R6VA 4ADMA 2O7DA 5F91A 2FUSA 2J91A 1B8FA 2PTSA 1FUOA 1C3CA 1FUPA 1RE5A 1TJ7A 4V2QA 2E9FA 4C5SA 5EYTA 1Y2MA 3E04A 2O78A 4FFXA 1YFEA 2X75A 1GKMA 1DCNA 4CQ5A 2QVEA 2RJRA 3RD8A 1YISA 4APAA 3TV2A 2NYFA 2O7BA 2RJSA 3BHGA 1I0AA 1FUQA 2VD6A 4BAAA 1VDKA 1GKJA 3QBPA 1J3UA 1C3UA 2QGAB 4HGVA 4MX2A 4V2RA 1TJWA 1U15A 5F92A 1U16A 1TJUA 1K62A 5HW2A 1GK2A 3KDYA 3KDZA 1KQ7A 1YFMA 4BABA 1XWOA 4APBA 1T6JA 2O7FA 3UNVA 1AUWA 1T6PA 3OCEA 1FURA 1K7WA 1Q5NA 1W27A 4NLEA 4FLCA 3GTDA 2YIIA 2HVGA 1JSWA 4C5RA 4NSLA 3R6YA 3C8TA 3RRPA 2PTQA 3NO9A 3R6QA 4C6GA 2PTRA 3GZHA 4EFCA 5D6BA 2OHYA 1HY1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2O6Y A;  3OCF A;  1GK3 A;  3NZ4 A;  3CZO A;  2PFM A;  1DOF A;  1HY0 A;  4EEI A;  5EYV A;  4C5U A;  4ADL A;  1EB4 A;  2O7E A;  1TJV A;  2NYN A;  3R6V A;  4ADM A;  2O7D A;  5F91 A;  2FUS A;  2J91 A;  1B8F A;  2PTS A;  1FUO A;  1C3C A;  1FUP A;  1RE5 A;  1TJ7 A;  4V2Q A;  2E9F A;  4C5S A;  5EYT A;  1Y2M A;  3E04 A;  2O78 A;  4FFX A;  1YFE A;  2X75 A;  1GKM A;  1DCN A;  4CQ5 A;  2QVE A;  2RJR A;  3RD8 A;  1YIS A;  4APA A;  3TV2 A;  2NYF A;  2O7B A;  2RJS A;  3BHG A;  1I0A A;  1FUQ A;  2VD6 A;  4BAA A;  1VDK A;  1GKJ A;  3QBP A;  1J3U A;  1C3U A;  2QGA B;  4HGV A;  4MX2 A;  4V2R A;  1TJW A;  1U15 A;  5F92 A;  1U16 A;  1TJU A;  1K62 A;  5HW2 A;  1GK2 A;  3KDY A;  3KDZ A;  1KQ7 A;  1YFM A;  4BAB A;  1XWO A;  4APB A;  1T6J A;  2O7F A;  3UNV A;  1AUW A;  1T6P A;  3OCE A;  1FUR A;  1K7W A;  1Q5N A;  1W27 A;  4NLE A;  4FLC A;  3GTD A;  2YII A;  2HVG A;  1JSW A;  4C5R A;  4NSL A;  3R6Y A;  3C8T A;  3RRP A;  2PTQ A;  3NO9 A;  3R6Q A;  4C6G A;  2PTR A;  3GZH A;  4EFC A;  5D6B A;  2OHY A;  1HY1 A; 
#chains in the Genus database with same CATH topology
 2FEL A;  2O6Y A;  3OCF A;  1GK3 A;  3NZ4 A;  4WNL A;  3CZO A;  2PFM A;  1DOF A;  1HY0 A;  4EEI A;  1XMD A;  2FEN A;  5EYV A;  4C5U A;  4ADL A;  1EB4 A;  2O7E A;  1TJV A;  2NYN A;  3R6V A;  4ADM A;  2O7D A;  5F91 A;  1XL8 A;  4A15 A;  2FUS A;  2J91 A;  5M0I A;  1B8F A;  2PTS A;  1FUO A;  1C3C A;  1FUP A;  1RE5 A;  1TJ7 A;  4V2Q A;  2E9F A;  4C5S A;  5EYT A;  1Y2M A;  3E04 A;  2O78 A;  4FFX A;  1YFE A;  2X75 A;  1GKM A;  1DCN A;  4CQ5 A;  2QVE A;  2RJR A;  3RD8 A;  1YIS A;  4APA A;  3TV2 A;  2NYF A;  2O7B A;  2RJS A;  3BHG A;  1I0A A;  1FUQ A;  2VD6 A;  4BAA A;  1VDK A;  1GKJ A;  3QBP A;  2VSF A;  1J3U A;  3CRV A;  1C3U A;  2QGA B;  4HGV A;  4MX2 A;  4V2R A;  1TJW A;  1XL7 A;  1U15 A;  5F92 A;  1U16 A;  5M0J A;  1TJU A;  1K62 A;  5HW2 A;  1GK2 A;  3KDY A;  1XMC A;  3KDZ A;  1KQ7 A;  2VL7 A;  1YFM A;  4BAB A;  1XWO A;  4APB A;  1T6J A;  2O7F A;  3UNV A;  1AUW A;  1T6P A;  3OCE A;  5H8W A;  1FUR A;  1K7W A;  1Q5N A;  1W27 A;  4NLE A;  1XLY A;  4FLC A;  3GTD A;  2YII A;  2HVG A;  1JSW A;  4C5R A;  4NSL A;  3R6Y A;  3C8T A;  3RRP A;  2PTQ A;  3NO9 A;  3R6Q A;  3CRW 1;  4C6G A;  2PTR A;  3GZH A;  4EFC A;  5D6B A;  2OHY A;  1HY1 A; 
#chains in the Genus database with same CATH homology
 2O6Y A;  3OCF A;  1GK3 A;  3NZ4 A;  3CZO A;  2PFM A;  1DOF A;  1HY0 A;  4EEI A;  5EYV A;  4C5U A;  4ADL A;  1EB4 A;  2O7E A;  1TJV A;  2NYN A;  3R6V A;  4ADM A;  2O7D A;  5F91 A;  2FUS A;  2J91 A;  1B8F A;  2PTS A;  1FUO A;  1C3C A;  1FUP A;  1RE5 A;  1TJ7 A;  4V2Q A;  2E9F A;  4C5S A;  5EYT A;  1Y2M A;  3E04 A;  2O78 A;  4FFX A;  1YFE A;  2X75 A;  1GKM A;  1DCN A;  4CQ5 A;  2QVE A;  2RJR A;  3RD8 A;  1YIS A;  4APA A;  3TV2 A;  2NYF A;  2O7B A;  2RJS A;  3BHG A;  1I0A A;  1FUQ A;  2VD6 A;  4BAA A;  1VDK A;  1GKJ A;  3QBP A;  1J3U A;  1C3U A;  2QGA B;  4HGV A;  4MX2 A;  4V2R A;  1TJW A;  1U15 A;  5F92 A;  1U16 A;  1TJU A;  1K62 A;  5HW2 A;  1GK2 A;  3KDY A;  3KDZ A;  1KQ7 A;  1YFM A;  4BAB A;  1XWO A;  4APB A;  1T6J A;  2O7F A;  3UNV A;  1AUW A;  1T6P A;  3OCE A;  1FUR A;  1K7W A;  1Q5N A;  1W27 A;  4NLE A;  4FLC A;  3GTD A;  2YII A;  2HVG A;  1JSW A;  4C5R A;  4NSL A;  3R6Y A;  3C8T A;  3RRP A;  2PTQ A;  3NO9 A;  3R6Q A;  4C6G A;  2PTR A;  3GZH A;  4EFC A;  5D6B A;  2OHY A;  1HY1 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...