2O7BA

Tyrosine ammonia-lyase from rhodobacter sphaeroides, complexed with coumarate
Total Genus 194
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
194
sequence length
515
structure length
514
Chain Sequence
PKPAVELDRHIDLDQAHAVASGGARIVLAPPARDRCRASEARLGAVIREARHVYGLTTGFGPLANRLISGENVRTLQANLVHHLASGVGPVLDWTTARAMVLARLVSIAQGASGASEGTIARLIDLLNSELAPAVPSRGTVGDLTPLAHMVLCLQGRGDFLDRDGTRLDGAEGLRRGRLQPLDLSHRDALALVNGTSAMTGIALVNAHACRHLGNWAVALTALLAECLRGRTEAWAAALSDLRPHPGQKDAAARLRARVDGSARVVRHVIAERRLDAGDIGTEPEAGQDAYSLRCAPQVLGAGFDTLAWHDRVLTIELNAVTDNPVFPPDGSVPALHGGNFMGQHVALTSDALATAVTVLAGLAERQIARLTDERLNRGLPPFLHRGPAGLNSGFMGAQVTATALLAEMRATGPASIHSISTNAANQDVVSLGTIAARLCREKIDRWAEILAILALCLAQAAELRCGSGLDGVSPAGKKLVQALREQFPPLETDRPLGQEIAALATHLLQQSPV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases.
pubmed doi rcsb
source organism Rhodobacter sphaeroides
molecule tags Lyase
molecule keywords Putative histidine ammonia-lyase
total genus 194
structure length 514
sequence length 515
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 4.3.1.23: Tyrosine ammonia-lyase.
pdb deposition date 2006-12-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 2o7bA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2o7bA02
2NYFA 4FLCA 2PTSA 3KDZA 4HGVA 1TJUA 3CZOA 2HVGA 4APAA 1EB4A 1GKJA 5D6BA 4C6GA 1YISA 1FUOA 2RJSA 1YFMA 1TJ7A 2J91A 1HY0A 2OHYA 1U15A 4NSLA 1FUQA 2O6YA 4NLEA 3OCEA 1HY1A 4FFXA 5F91A 2E9FA 1GK3A 1XWOA 1Y2MA 1W27A 3KDYA 4APBA 1TJVA 2NYNA 1VDKA 3TV2A 2QVEA 3OCFA 3NZ4A 1K7WA 2QGAB 2O78A 3R6YA 4V2QA 4C5UA 1C3UA 2O7DA 1FUPA 1Q5NA 4V2RA 1K62A 4EEIA 2X75A 3E04A 3BHGA 2O7BA 1YFEA 4CQ5A 3QBPA 3GTDA 3C8TA 5EYVA 1TJWA 3RRPA 1B8FA 4ADMA 2RJRA 5F92A 1RE5A 5HW2A 3UNVA 1U16A 1T6PA 1I0AA 5EYTA 1T6JA 1AUWA 2FUSA 4C5SA 1DOFA 4MX2A 2O7FA 2VD6A 2O7EA 4BABA 2PTQA 1C3CA 1GK2A 3R6QA 4C5RA 1JSWA 1GKMA 1DCNA 4BAAA 3GZHA 1FURA 3RD8A 1J3UA 1KQ7A 4ADLA 2PTRA 2YIIA 4EFCA 3NO9A 3R6VA 2PFMA
chains in the Genus database with same CATH superfamily
2NYFA 4FLCA 2PTSA 3KDZA 4HGVA 1TJUA 3CZOA 2HVGA 4APAA 1EB4A 1GKJA 2VSFA 5M0JA 5D6BA 1XLYA 4C6GA 1YISA 1FUOA 2RJSA 1YFMA 1TJ7A 2J91A 1XL8A 1HY0A 2OHYA 4A15A 1U15A 4NSLA 2FENA 1FUQA 2O6YA 4NLEA 3OCEA 1HY1A 4FFXA 1XMDA 5F91A 2E9FA 1GK3A 1XWOA 1Y2MA 1W27A 3KDYA 4APBA 1TJVA 2NYNA 1VDKA 3TV2A 2QVEA 3OCFA 2VL7A 5H8WA 3NZ4A 1K7WA 2QGAB 2O78A 3R6YA 4V2QA 4C5UA 1XL7A 1C3UA 2O7DA 1FUPA 1Q5NA 4V2RA 1K62A 4EEIA 2X75A 3E04A 3BHGA 2O7BA 1YFEA 4CQ5A 3QBPA 3GTDA 3C8TA 5EYVA 1TJWA 3RRPA 1B8FA 4ADMA 2RJRA 5F92A 1RE5A 5HW2A 3UNVA 1U16A 1T6PA 1I0AA 5EYTA 1T6JA 1AUWA 2FUSA 4C5SA 1DOFA 4MX2A 2O7FA 2VD6A 2O7EA 4BABA 2PTQA 5M0IA 1C3CA 1GK2A 3R6QA 4C5RA 1JSWA 1GKMA 1DCNA 4BAAA 3GZHA 1FURA 4WNLA 3RD8A 1J3UA 1KQ7A 4ADLA 2PTRA 2FELA 1XMCA 2YIIA 4EFCA 3CRVA 3NO9A 3R6VA 3CRW1 2PFMA
chains in the Genus database with same CATH topology
2NYFA 4FLCA 2PTSA 3KDZA 4HGVA 1TJUA 3CZOA 2HVGA 4APAA 1EB4A 1GKJA 5D6BA 4C6GA 1YISA 1FUOA 2RJSA 1YFMA 1TJ7A 2J91A 1HY0A 2OHYA 1U15A 4NSLA 1FUQA 2O6YA 4NLEA 3OCEA 1HY1A 4FFXA 5F91A 2E9FA 1GK3A 1XWOA 1Y2MA 1W27A 3KDYA 4APBA 1TJVA 2NYNA 1VDKA 3TV2A 2QVEA 3OCFA 3NZ4A 1K7WA 2QGAB 2O78A 3R6YA 4V2QA 4C5UA 1C3UA 2O7DA 1FUPA 1Q5NA 4V2RA 1K62A 4EEIA 2X75A 3E04A 3BHGA 2O7BA 1YFEA 4CQ5A 3QBPA 3GTDA 3C8TA 5EYVA 1TJWA 3RRPA 1B8FA 4ADMA 2RJRA 5F92A 1RE5A 5HW2A 3UNVA 1U16A 1T6PA 1I0AA 5EYTA 1T6JA 1AUWA 2FUSA 4C5SA 1DOFA 4MX2A 2O7FA 2VD6A 2O7EA 4BABA 2PTQA 1C3CA 1GK2A 3R6QA 4C5RA 1JSWA 1GKMA 1DCNA 4BAAA 3GZHA 1FURA 3RD8A 1J3UA 1KQ7A 4ADLA 2PTRA 2YIIA 4EFCA 3NO9A 3R6VA 2PFMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NYF A;  4FLC A;  2PTS A;  3KDZ A;  4HGV A;  1TJU A;  3CZO A;  2HVG A;  4APA A;  1EB4 A;  1GKJ A;  5D6B A;  4C6G A;  1YIS A;  1FUO A;  2RJS A;  1YFM A;  1TJ7 A;  2J91 A;  1HY0 A;  2OHY A;  1U15 A;  4NSL A;  1FUQ A;  2O6Y A;  4NLE A;  3OCE A;  1HY1 A;  4FFX A;  5F91 A;  2E9F A;  1GK3 A;  1XWO A;  1Y2M A;  1W27 A;  3KDY A;  4APB A;  1TJV A;  2NYN A;  1VDK A;  3TV2 A;  2QVE A;  3OCF A;  3NZ4 A;  1K7W A;  2QGA B;  2O78 A;  3R6Y A;  4V2Q A;  4C5U A;  1C3U A;  2O7D A;  1FUP A;  1Q5N A;  4V2R A;  1K62 A;  4EEI A;  2X75 A;  3E04 A;  3BHG A;  2O7B A;  1YFE A;  4CQ5 A;  3QBP A;  3GTD A;  3C8T A;  5EYV A;  1TJW A;  3RRP A;  1B8F A;  4ADM A;  2RJR A;  5F92 A;  1RE5 A;  5HW2 A;  3UNV A;  1U16 A;  1T6P A;  1I0A A;  5EYT A;  1T6J A;  1AUW A;  2FUS A;  4C5S A;  1DOF A;  4MX2 A;  2O7F A;  2VD6 A;  2O7E A;  4BAB A;  2PTQ A;  1C3C A;  1GK2 A;  3R6Q A;  4C5R A;  1JSW A;  1GKM A;  1DCN A;  4BAA A;  3GZH A;  1FUR A;  3RD8 A;  1J3U A;  1KQ7 A;  4ADL A;  2PTR A;  2YII A;  4EFC A;  3NO9 A;  3R6V A;  2PFM A; 
#chains in the Genus database with same CATH topology
 2NYF A;  4FLC A;  2PTS A;  3KDZ A;  4HGV A;  1TJU A;  3CZO A;  2HVG A;  4APA A;  1EB4 A;  1GKJ A;  2VSF A;  5M0J A;  5D6B A;  1XLY A;  4C6G A;  1YIS A;  1FUO A;  2RJS A;  1YFM A;  1TJ7 A;  2J91 A;  1XL8 A;  1HY0 A;  2OHY A;  4A15 A;  1U15 A;  4NSL A;  2FEN A;  1FUQ A;  2O6Y A;  4NLE A;  3OCE A;  1HY1 A;  4FFX A;  1XMD A;  5F91 A;  2E9F A;  1GK3 A;  1XWO A;  1Y2M A;  1W27 A;  3KDY A;  4APB A;  1TJV A;  2NYN A;  1VDK A;  3TV2 A;  2QVE A;  3OCF A;  2VL7 A;  5H8W A;  3NZ4 A;  1K7W A;  2QGA B;  2O78 A;  3R6Y A;  4V2Q A;  4C5U A;  1XL7 A;  1C3U A;  2O7D A;  1FUP A;  1Q5N A;  4V2R A;  1K62 A;  4EEI A;  2X75 A;  3E04 A;  3BHG A;  2O7B A;  1YFE A;  4CQ5 A;  3QBP A;  3GTD A;  3C8T A;  5EYV A;  1TJW A;  3RRP A;  1B8F A;  4ADM A;  2RJR A;  5F92 A;  1RE5 A;  5HW2 A;  3UNV A;  1U16 A;  1T6P A;  1I0A A;  5EYT A;  1T6J A;  1AUW A;  2FUS A;  4C5S A;  1DOF A;  4MX2 A;  2O7F A;  2VD6 A;  2O7E A;  4BAB A;  2PTQ A;  5M0I A;  1C3C A;  1GK2 A;  3R6Q A;  4C5R A;  1JSW A;  1GKM A;  1DCN A;  4BAA A;  3GZH A;  1FUR A;  4WNL A;  3RD8 A;  1J3U A;  1KQ7 A;  4ADL A;  2PTR A;  2FEL A;  1XMC A;  2YII A;  4EFC A;  3CRV A;  3NO9 A;  3R6V A;  3CRW 1;  2PFM A; 
#chains in the Genus database with same CATH homology
 2NYF A;  4FLC A;  2PTS A;  3KDZ A;  4HGV A;  1TJU A;  3CZO A;  2HVG A;  4APA A;  1EB4 A;  1GKJ A;  5D6B A;  4C6G A;  1YIS A;  1FUO A;  2RJS A;  1YFM A;  1TJ7 A;  2J91 A;  1HY0 A;  2OHY A;  1U15 A;  4NSL A;  1FUQ A;  2O6Y A;  4NLE A;  3OCE A;  1HY1 A;  4FFX A;  5F91 A;  2E9F A;  1GK3 A;  1XWO A;  1Y2M A;  1W27 A;  3KDY A;  4APB A;  1TJV A;  2NYN A;  1VDK A;  3TV2 A;  2QVE A;  3OCF A;  3NZ4 A;  1K7W A;  2QGA B;  2O78 A;  3R6Y A;  4V2Q A;  4C5U A;  1C3U A;  2O7D A;  1FUP A;  1Q5N A;  4V2R A;  1K62 A;  4EEI A;  2X75 A;  3E04 A;  3BHG A;  2O7B A;  1YFE A;  4CQ5 A;  3QBP A;  3GTD A;  3C8T A;  5EYV A;  1TJW A;  3RRP A;  1B8F A;  4ADM A;  2RJR A;  5F92 A;  1RE5 A;  5HW2 A;  3UNV A;  1U16 A;  1T6P A;  1I0A A;  5EYT A;  1T6J A;  1AUW A;  2FUS A;  4C5S A;  1DOF A;  4MX2 A;  2O7F A;  2VD6 A;  2O7E A;  4BAB A;  2PTQ A;  1C3C A;  1GK2 A;  3R6Q A;  4C5R A;  1JSW A;  1GKM A;  1DCN A;  4BAA A;  3GZH A;  1FUR A;  3RD8 A;  1J3U A;  1KQ7 A;  4ADL A;  2PTR A;  2YII A;  4EFC A;  3NO9 A;  3R6V A;  2PFM A; 
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