2O7BA

Tyrosine ammonia-lyase from rhodobacter sphaeroides, complexed with coumarate
Total Genus 194
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
194
sequence length
515
structure length
514
Chain Sequence
b'PKPAVELDRHIDLDQAHAVASGGARIVLAPPARDRCRASEARLGAVIREARHVYGLTTGFGPLANRLISGENVRTLQANLVHHLASGVGPVLDWTTARAMVLARLVSIAQGASGASEGTIARLIDLLNSELAPAVPSRGTVGDLTPLAHMVLCLQGRGDFLDRDGTRLDGAEGLRRGRLQPLDLSHRDALALVNGTSAMTGIALVNAHACRHLGNWAVALTALLAECLRGRTEAWAAALSDLRPHPGQKDAAARLRARVDGSARVVRHVIAERRLDAGDIGTEPEAGQDAYSLRCAPQVLGAGFDTLAWHDRVLTIELNAVTDNPVFPPDGSVPALHGGNFMGQHVALTSDALATAVTVLAGLAERQIARLTDERLNRGLPPFLHRGPAGLNSGFMGAQVTATALLAEMRATGPASIHSISTNAANQDVVSLGTIAARLCREKIDRWAEILAILALCLAQAAELRCGSGLDGVSPAGKKLVQALREQFPPLETDRPLGQEIAALATHLLQQSPV'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Putative histidine ammonia-lyase
publication title Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases.
pubmed doi rcsb
source organism Rhodobacter sphaeroides
molecule tags Lyase
total genus 194
structure length 514
sequence length 515
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 4.3.1.23: Tyrosine ammonia-lyase.
pdb deposition date 2006-12-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 2o7bA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 2o7bA02
2O78A 1DCNA 3UNVA 4EFCA 1AUWA 5F91A 1YISA 2O7FA 1I0AA 4C5UA 4V2QA 4MX2A 1TJ7A 4HGVA 1XWOA 1FURA 1FUQA 1YFMA 2PTQA 2PTRA 1Y2MA 1HY1A 3GZHA 3NO9A 1B8FA 2O7EA 4C5SA 1GK3A 5F92A 3NZ4A 3OCFA 2NYFA 2PFMA 5EYTA 4BABA 4NLEA 3E04A 2QVEA 4ADLA 1YFEA 1C3CA 3R6QA 4NSLA 2HVGA 1J3UA 3KDZA 3R6VA 1TJWA 1FUPA 1U15A 4FLCA 2OHYA 1K62A 1JSWA 4APBA 1U16A 3OCEA 3CZOA 1DOFA 2VD6A 2FUSA 2PTSA 3RD8A 1EB4A 4C6GA 1VDKA 3QBPA 4C5RA 1T6PA 3KDYA 2O6YA 1GK2A 5EYVA 3C8TA 1RE5A 1TJVA 4V2RA 1GKMA 3BHGA 2YIIA 2RJRA 3TV2A 1FUOA 1K7WA 1C3UA 4FFXA 1TJUA 2X75A 3RRPA 4APAA 2O7BA 4ADMA 2O7DA 3GTDA 2J91A 2QGAB 5D6BA 4BAAA 1KQ7A 3R6YA 4CQ5A 4EEIA 1HY0A 1W27A 1T6JA 2NYNA 1Q5NA 2E9FA 1GKJA 5HW2A 2RJSA
chains in the Genus database with same CATH superfamily
2O78A 1DCNA 3CRVA 3UNVA 4EFCA 1AUWA 5F91A 1YISA 2O7FA 1I0AA 4C5UA 4V2QA 4MX2A 1TJ7A 4HGVA 1XWOA 1FURA 1FUQA 1YFMA 2PTQA 1XMCA 2PTRA 1Y2MA 1HY1A 2VSFA 3GZHA 3NO9A 1B8FA 2O7EA 4C5SA 1GK3A 5M0JA 5F92A 3NZ4A 3OCFA 2FENA 2NYFA 1XMDA 2PFMA 5EYTA 4BABA 4NLEA 3E04A 2QVEA 4ADLA 1YFEA 1C3CA 3R6QA 4NSLA 2HVGA 1J3UA 3KDZA 3R6VA 1TJWA 1FUPA 1U15A 4FLCA 2OHYA 1K62A 1JSWA 4APBA 1U16A 3OCEA 3CZOA 1DOFA 2VD6A 2FUSA 5H8WA 2PTSA 3RD8A 1EB4A 4C6GA 1VDKA 3QBPA 4C5RA 1T6PA 3KDYA 1XLYA 2O6YA 1GK2A 5EYVA 3C8TA 1RE5A 3CRW1 1TJVA 4V2RA 1GKMA 3BHGA 2YIIA 2RJRA 3TV2A 1FUOA 1K7WA 1C3UA 4FFXA 1TJUA 2X75A 3RRPA 4APAA 2O7BA 4ADMA 1XL8A 2O7DA 3GTDA 2J91A 4WNLA 2QGAB 5D6BA 4BAAA 1KQ7A 2VL7A 3R6YA 4CQ5A 4EEIA 1HY0A 5M0IA 1W27A 1T6JA 4A15A 2NYNA 2FELA 1Q5NA 2E9FA 1GKJA 1XL7A 5HW2A 2RJSA
chains in the Genus database with same CATH topology
2O78A 1DCNA 3UNVA 4EFCA 1AUWA 5F91A 1YISA 2O7FA 1I0AA 4C5UA 4V2QA 4MX2A 1TJ7A 4HGVA 1XWOA 1FURA 1FUQA 1YFMA 2PTQA 2PTRA 1Y2MA 1HY1A 3GZHA 3NO9A 1B8FA 2O7EA 4C5SA 1GK3A 5F92A 3NZ4A 3OCFA 2NYFA 2PFMA 5EYTA 4BABA 4NLEA 3E04A 2QVEA 4ADLA 1YFEA 1C3CA 3R6QA 4NSLA 2HVGA 1J3UA 3KDZA 3R6VA 1TJWA 1FUPA 1U15A 4FLCA 2OHYA 1K62A 1JSWA 4APBA 1U16A 3OCEA 3CZOA 1DOFA 2VD6A 2FUSA 2PTSA 3RD8A 1EB4A 4C6GA 1VDKA 3QBPA 4C5RA 1T6PA 3KDYA 2O6YA 1GK2A 5EYVA 3C8TA 1RE5A 1TJVA 4V2RA 1GKMA 3BHGA 2YIIA 2RJRA 3TV2A 1FUOA 1K7WA 1C3UA 4FFXA 1TJUA 2X75A 3RRPA 4APAA 2O7BA 4ADMA 2O7DA 3GTDA 2J91A 2QGAB 5D6BA 4BAAA 1KQ7A 3R6YA 4CQ5A 4EEIA 1HY0A 1W27A 1T6JA 2NYNA 1Q5NA 2E9FA 1GKJA 5HW2A 2RJSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2O78 A;  1DCN A;  3UNV A;  4EFC A;  1AUW A;  5F91 A;  1YIS A;  2O7F A;  1I0A A;  4C5U A;  4V2Q A;  4MX2 A;  1TJ7 A;  4HGV A;  1XWO A;  1FUR A;  1FUQ A;  1YFM A;  2PTQ A;  2PTR A;  1Y2M A;  1HY1 A;  3GZH A;  3NO9 A;  1B8F A;  2O7E A;  4C5S A;  1GK3 A;  5F92 A;  3NZ4 A;  3OCF A;  2NYF A;  2PFM A;  5EYT A;  4BAB A;  4NLE A;  3E04 A;  2QVE A;  4ADL A;  1YFE A;  1C3C A;  3R6Q A;  4NSL A;  2HVG A;  1J3U A;  3KDZ A;  3R6V A;  1TJW A;  1FUP A;  1U15 A;  4FLC A;  2OHY A;  1K62 A;  1JSW A;  4APB A;  1U16 A;  3OCE A;  3CZO A;  1DOF A;  2VD6 A;  2FUS A;  2PTS A;  3RD8 A;  1EB4 A;  4C6G A;  1VDK A;  3QBP A;  4C5R A;  1T6P A;  3KDY A;  2O6Y A;  1GK2 A;  5EYV A;  3C8T A;  1RE5 A;  1TJV A;  4V2R A;  1GKM A;  3BHG A;  2YII A;  2RJR A;  3TV2 A;  1FUO A;  1K7W A;  1C3U A;  4FFX A;  1TJU A;  2X75 A;  3RRP A;  4APA A;  2O7B A;  4ADM A;  2O7D A;  3GTD A;  2J91 A;  2QGA B;  5D6B A;  4BAA A;  1KQ7 A;  3R6Y A;  4CQ5 A;  4EEI A;  1HY0 A;  1W27 A;  1T6J A;  2NYN A;  1Q5N A;  2E9F A;  1GKJ A;  5HW2 A;  2RJS A; 
#chains in the Genus database with same CATH topology
 2O78 A;  1DCN A;  3CRV A;  3UNV A;  4EFC A;  1AUW A;  5F91 A;  1YIS A;  2O7F A;  1I0A A;  4C5U A;  4V2Q A;  4MX2 A;  1TJ7 A;  4HGV A;  1XWO A;  1FUR A;  1FUQ A;  1YFM A;  2PTQ A;  1XMC A;  2PTR A;  1Y2M A;  1HY1 A;  2VSF A;  3GZH A;  3NO9 A;  1B8F A;  2O7E A;  4C5S A;  1GK3 A;  5M0J A;  5F92 A;  3NZ4 A;  3OCF A;  2FEN A;  2NYF A;  1XMD A;  2PFM A;  5EYT A;  4BAB A;  4NLE A;  3E04 A;  2QVE A;  4ADL A;  1YFE A;  1C3C A;  3R6Q A;  4NSL A;  2HVG A;  1J3U A;  3KDZ A;  3R6V A;  1TJW A;  1FUP A;  1U15 A;  4FLC A;  2OHY A;  1K62 A;  1JSW A;  4APB A;  1U16 A;  3OCE A;  3CZO A;  1DOF A;  2VD6 A;  2FUS A;  5H8W A;  2PTS A;  3RD8 A;  1EB4 A;  4C6G A;  1VDK A;  3QBP A;  4C5R A;  1T6P A;  3KDY A;  1XLY A;  2O6Y A;  1GK2 A;  5EYV A;  3C8T A;  1RE5 A;  3CRW 1;  1TJV A;  4V2R A;  1GKM A;  3BHG A;  2YII A;  2RJR A;  3TV2 A;  1FUO A;  1K7W A;  1C3U A;  4FFX A;  1TJU A;  2X75 A;  3RRP A;  4APA A;  2O7B A;  4ADM A;  1XL8 A;  2O7D A;  3GTD A;  2J91 A;  4WNL A;  2QGA B;  5D6B A;  4BAA A;  1KQ7 A;  2VL7 A;  3R6Y A;  4CQ5 A;  4EEI A;  1HY0 A;  5M0I A;  1W27 A;  1T6J A;  4A15 A;  2NYN A;  2FEL A;  1Q5N A;  2E9F A;  1GKJ A;  1XL7 A;  5HW2 A;  2RJS A; 
#chains in the Genus database with same CATH homology
 2O78 A;  1DCN A;  3UNV A;  4EFC A;  1AUW A;  5F91 A;  1YIS A;  2O7F A;  1I0A A;  4C5U A;  4V2Q A;  4MX2 A;  1TJ7 A;  4HGV A;  1XWO A;  1FUR A;  1FUQ A;  1YFM A;  2PTQ A;  2PTR A;  1Y2M A;  1HY1 A;  3GZH A;  3NO9 A;  1B8F A;  2O7E A;  4C5S A;  1GK3 A;  5F92 A;  3NZ4 A;  3OCF A;  2NYF A;  2PFM A;  5EYT A;  4BAB A;  4NLE A;  3E04 A;  2QVE A;  4ADL A;  1YFE A;  1C3C A;  3R6Q A;  4NSL A;  2HVG A;  1J3U A;  3KDZ A;  3R6V A;  1TJW A;  1FUP A;  1U15 A;  4FLC A;  2OHY A;  1K62 A;  1JSW A;  4APB A;  1U16 A;  3OCE A;  3CZO A;  1DOF A;  2VD6 A;  2FUS A;  2PTS A;  3RD8 A;  1EB4 A;  4C6G A;  1VDK A;  3QBP A;  4C5R A;  1T6P A;  3KDY A;  2O6Y A;  1GK2 A;  5EYV A;  3C8T A;  1RE5 A;  1TJV A;  4V2R A;  1GKM A;  3BHG A;  2YII A;  2RJR A;  3TV2 A;  1FUO A;  1K7W A;  1C3U A;  4FFX A;  1TJU A;  2X75 A;  3RRP A;  4APA A;  2O7B A;  4ADM A;  2O7D A;  3GTD A;  2J91 A;  2QGA B;  5D6B A;  4BAA A;  1KQ7 A;  3R6Y A;  4CQ5 A;  4EEI A;  1HY0 A;  1W27 A;  1T6J A;  2NYN A;  1Q5N A;  2E9F A;  1GKJ A;  5HW2 A;  2RJS A; 
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