2O8AA

Rat pp1cgamma complexed with mouse inhibitor-2
Total Genus 112
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
112
sequence length
295
structure length
295
Chain Sequence
KLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for regulation of protein phosphatase 1 by inhibitor-2.
pubmed doi rcsb
molecule tags Hydrolase/inhibitor
source organism Rattus norvegicus
molecule keywords Serine/threonine-protein phosphatase PP1-gamma catalytic sub
total genus 112
structure length 295
sequence length 295
chains with identical sequence B
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2006-12-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
A PF16891 STPPase_N Serine-threonine protein phosphatase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 2o8aA00
2R17A 3QFOA 4FCXA 2ZBMA 3H63A 4FBQA 3K7VC 4LTYA 1HP1A 4V0XA 4UT3A 4H2IA 2HY1A 2BCDA 3H69A 1G5BA 2Z06A 4OR9A 1II7A 4UT2A 2BDXA 2WDFA 3QG5C 4TUIA 1SU1A 3H68A 4O43A 1QHWA 1IT6A 1JK7A 3ZTVA 4MOYA 1Z2XA 1HO5A 1WAO1 3H67A 3PSOA 1AUIA 4I5NC 4UWQA 4FBKA 5C1VA 5HPEA 2WDEA 1V73A 4JA9A 3QFMA 1TCOA 1S3LA 4ORBA 3KBPA 4LACC 4H2BA 2HYOA 2QFPA 3PSNA 3K7WC 2CV9A 3H61A 2KKNA 1UTEA 3N5UA 3LL8A 2A22A 3EGGA 4HD0A 2Z1AA 2HYPA 4M0VA 4B2OA 4UT3B 3ZU0A 5INBA 4G9JA 4JA7A 4O5GA 4V0VA 4ZVZA 5B8IA 2BQ8X 1QFCA 1FJMA 4I5LC 2P6BA 3IVDA 1UF3A 3IVEA 3DW8C 3H64A 4DSYA 4Q7FA 1NNWA 2XMOA 4DHLA 4IL1A 2YVTA 5JPEA 4LU9A 3EGHA 3FGAC 3HVQA 3RL4A 4NZVA 2NYLC 3CK2A 3RL3A 3THOB 5DNYA 1T70A 3IB8A 2AHDA 3IB7A 4ORCA 5JJTA 2DFJA 3QFNA 3DSDA 1KBPA 3E7BA 4H2FA 5GTUA 3DSCA 1OI8A 2QFRA 2Z72A 1XM7A 4ORAA 2IE4C 4WWLA 4XPNA 2QJCA 4KBPA 4KKZA 5F3WA 3JYFA 3P71C 1OIDA 1OIEA 1S95A 5EQVA 3T1IA 1W24A 1S70A 4F0ZA 3V4YA 1S3MA 4DT2A 4TUGA 1HPUA 4V0WA 5J28A 2NXFA 2JOGA 3H66A 2O8AA 4YKEA 2WDCA 4O24A 1MF8A 2NYMC 3C9FA 2WDDA 3H62B 3H60A 4ZX2A 1Z2WA 3GVEA 3THNA 3QFKA 1T71A 1S3NA 1U32A 1XZWA 2O8GA 4H1YP 3TGHA 4FBWA 5IOHA 3AV0A 3AUZA 4MOVA 4H2GA 3RL5A 1USHA 3C5WC 1M63A 4O4KA 5JPFA 4MP0A 2IAEC 1WARA 2Q8UA 4H1SA 2IE3C 4J6OA 1S8EA 3E7AA 2GJUA 3ICFA 2USHA 2NPPC 4IYPC 3RQZA
chains in the Genus database with same CATH superfamily
3E0JA 2R17A 3QFOA 2ZO9B 4FCXA 2ZBMA 3H63A 4FBQA 3K7VC 4LTYA 1HP1A 4V0XA 4UT3A 4H2IA 2HY1A 2BCDA 3H69A 1G5BA 2Z06A 4OR9A 1II7A 3D03A 4UT2A 2BDXA 2WDFA 3QG5C 4TUIA 1SU1A 3H68A 4O43A 1QHWA 1IT6A 1JK7A 3ZTVA 4MOYA 1Z2XA 1HO5A 1WAO1 3FLOA 3H67A 3PSOA 1AUIA 4I5NC 4UWQA 4FBKA 5C1VA 5HPEA 2WDEA 1V73A 4JA9A 3QFMA 1TCOA 1S3LA 4ORBA 3KBPA 4LACC 2DXNA 4H2BA 2HYOA 2QFPA 3PSNA 3K7WC 2CV9A 3H61A 2KKNA 1UTEA 3N5UA 3LL8A 2A22A 3EGGA 4HD0A 2Z1AA 2HYPA 4M0VA 4B2OA 4UT3B 3ZU0A 5INBA 4G9JA 4JA7A 4O5GA 4V0VA 2DXLA 4ZVZA 2BQ8X 1QFCA 1FJMA 4I5LC 5B8IA 2P6BA 3IVDA 1UF3A 3IVEA 3DW8C 3H64A 4DSYA 4Q7FA 1NNWA 2XMOA 4DHLA 4IL1A 2YVTA 5JPEA 4LU9A 3EGHA 3FGAC 3HVQA 3RL4A 4NZVA 2NYLC 3CK2A 3RL3A 3THOB 5DNYA 1T70A 3IB8A 2ZOAA 2AHDA 3IB7A 4ORCA 5JJTA 2DFJA 3QFNA 3DSDA 1KBPA 3E7BA 4H2FA 5GTUA 3DSCA 1OI8A 2QFRA 2Z72A 1XM7A 4ORAA 2IE4C 4WWLA 4XPNA 2QJCA 4KBPA 4KKZA 5F3WA 3JYFA 3P71C 1OIDA 1OIEA 1S95A 5EQVA 3T1IA 1W24A 1S70A 4F0ZA 3V4YA 1S3MA 4DT2A 4TUGA 1HPUA 4V0WA 5J28A 2NXFA 2JOGA 3H66A 2O8AA 4YKEA 2WDCA 4O24A 1MF8A 2NYMC 3C9FA 2WDDA 3H62B 3H60A 4ZX2A 1Z2WA 3GVEA 3THNA 3QFKA 1T71A 1S3NA 1U32A 1XZWA 2O8GA 4H1YP 3TGHA 4FBWA 5IOHA 3AV0A 3AUZA 4MOVA 4H2GA 3RL5A 1USHA 3C5WC 1M63A 4O4KA 5JPFA 2YEQA 4MP0A 2IAEC 1WARA 2Q8UA 4H1SA 2IE3C 4J6OA 1S8EA 3E7AA 2GJUA 3ICFA 2USHA 2NPPC 4IYPC 3RQZA
chains in the Genus database with same CATH topology
3E0JA 2R17A 3QFOA 2ZO9B 4FCXA 2ZBMA 3H63A 4FBQA 3K7VC 4LTYA 1HP1A 4V0XA 4UT3A 4H2IA 2HY1A 2BCDA 3H69A 1G5BA 2Z06A 4OR9A 1II7A 3D03A 4UT2A 2BDXA 2WDFA 3QG5C 4TUIA 1SU1A 3H68A 4O43A 1QHWA 1IT6A 1JK7A 3ZTVA 4MOYA 1Z2XA 1HO5A 1WAO1 3FLOA 3H67A 3PSOA 1AUIA 4I5NC 4UWQA 4FBKA 5C1VA 5HPEA 2WDEA 1V73A 4JA9A 3QFMA 1TCOA 1S3LA 4ORBA 3KBPA 4LACC 2DXNA 4H2BA 2HYOA 2QFPA 3PSNA 3K7WC 2CV9A 3H61A 2KKNA 1UTEA 3N5UA 3LL8A 2A22A 3EGGA 4HD0A 2Z1AA 2HYPA 4M0VA 4B2OA 4UT3B 3ZU0A 5INBA 4G9JA 4JA7A 4O5GA 4V0VA 2DXLA 4ZVZA 2BQ8X 1QFCA 1FJMA 4I5LC 5B8IA 2P6BA 3IVDA 1UF3A 3IVEA 3DW8C 3H64A 4DSYA 4Q7FA 1NNWA 2XMOA 4DHLA 4IL1A 2YVTA 5JPEA 4LU9A 3EGHA 3FGAC 3HVQA 3RL4A 4NZVA 2NYLC 3CK2A 3RL3A 3THOB 5DNYA 1T70A 3IB8A 2ZOAA 2AHDA 3IB7A 4ORCA 5JJTA 2DFJA 3QFNA 3DSDA 1KBPA 3E7BA 4H2FA 5GTUA 3DSCA 1OI8A 2QFRA 2Z72A 1XM7A 4ORAA 2IE4C 4WWLA 4XPNA 2QJCA 4KBPA 4KKZA 5F3WA 3JYFA 3P71C 1OIDA 1OIEA 1S95A 5EQVA 3T1IA 1W24A 1S70A 4F0ZA 3V4YA 1S3MA 4DT2A 4TUGA 1HPUA 4V0WA 5J28A 2NXFA 2JOGA 3H66A 2O8AA 4YKEA 2WDCA 4O24A 1MF8A 2NYMC 3C9FA 2WDDA 3H62B 3H60A 4ZX2A 1Z2WA 3GVEA 3THNA 3QFKA 1T71A 1S3NA 1U32A 1XZWA 2O8GA 4H1YP 3TGHA 4FBWA 5IOHA 3AV0A 3AUZA 4MOVA 4H2GA 3RL5A 1USHA 3C5WC 1M63A 4O4KA 5JPFA 2YEQA 4MP0A 2IAEC 1WARA 2Q8UA 4H1SA 2IE3C 4J6OA 1S8EA 3E7AA 2GJUA 3ICFA 2USHA 2NPPC 4IYPC 3RQZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2R17 A;  3QFO A;  4FCX A;  2ZBM A;  3H63 A;  4FBQ A;  3K7V C;  4LTY A;  1HP1 A;  4V0X A;  4UT3 A;  4H2I A;  2HY1 A;  2BCD A;  3H69 A;  1G5B A;  2Z06 A;  4OR9 A;  1II7 A;  4UT2 A;  2BDX A;  2WDF A;  3QG5 C;  4TUI A;  1SU1 A;  3H68 A;  4O43 A;  1QHW A;  1IT6 A;  1JK7 A;  3ZTV A;  4MOY A;  1Z2X A;  1HO5 A;  1WAO 1;  3H67 A;  3PSO A;  1AUI A;  4I5N C;  4UWQ A;  4FBK A;  5C1V A;  5HPE A;  2WDE A;  1V73 A;  4JA9 A;  3QFM A;  1TCO A;  1S3L A;  4ORB A;  3KBP A;  4LAC C;  4H2B A;  2HYO A;  2QFP A;  3PSN A;  3K7W C;  2CV9 A;  3H61 A;  2KKN A;  1UTE A;  3N5U A;  3LL8 A;  2A22 A;  3EGG A;  4HD0 A;  2Z1A A;  2HYP A;  4M0V A;  4B2O A;  4UT3 B;  3ZU0 A;  5INB A;  4G9J A;  4JA7 A;  4O5G A;  4V0V A;  4ZVZ A;  5B8I A;  2BQ8 X;  1QFC A;  1FJM A;  4I5L C;  2P6B A;  3IVD A;  1UF3 A;  3IVE A;  3DW8 C;  3H64 A;  4DSY A;  4Q7F A;  1NNW A;  2XMO A;  4DHL A;  4IL1 A;  2YVT A;  5JPE A;  4LU9 A;  3EGH A;  3FGA C;  3HVQ A;  3RL4 A;  4NZV A;  2NYL C;  3CK2 A;  3RL3 A;  3THO B;  5DNY A;  1T70 A;  3IB8 A;  2AHD A;  3IB7 A;  4ORC A;  5JJT A;  2DFJ A;  3QFN A;  3DSD A;  1KBP A;  3E7B A;  4H2F A;  5GTU A;  3DSC A;  1OI8 A;  2QFR A;  2Z72 A;  1XM7 A;  4ORA A;  2IE4 C;  4WWL A;  4XPN A;  2QJC A;  4KBP A;  4KKZ A;  5F3W A;  3JYF A;  3P71 C;  1OID A;  1OIE A;  1S95 A;  5EQV A;  3T1I A;  1W24 A;  1S70 A;  4F0Z A;  3V4Y A;  1S3M A;  4DT2 A;  4TUG A;  1HPU A;  4V0W A;  5J28 A;  2NXF A;  2JOG A;  3H66 A;  2O8A A;  4YKE A;  2WDC A;  4O24 A;  1MF8 A;  2NYM C;  3C9F A;  2WDD A;  3H62 B;  3H60 A;  4ZX2 A;  1Z2W A;  3GVE A;  3THN A;  3QFK A;  1T71 A;  1S3N A;  1U32 A;  1XZW A;  2O8G A;  4H1Y P;  3TGH A;  4FBW A;  5IOH A;  3AV0 A;  3AUZ A;  4MOV A;  4H2G A;  3RL5 A;  1USH A;  3C5W C;  1M63 A;  4O4K A;  5JPF A;  4MP0 A;  2IAE C;  1WAR A;  2Q8U A;  4H1S A;  2IE3 C;  4J6O A;  1S8E A;  3E7A A;  2GJU A;  3ICF A;  2USH A;  2NPP C;  4IYP C;  3RQZ A; 
#chains in the Genus database with same CATH topology
 3E0J A;  2R17 A;  3QFO A;  2ZO9 B;  4FCX A;  2ZBM A;  3H63 A;  4FBQ A;  3K7V C;  4LTY A;  1HP1 A;  4V0X A;  4UT3 A;  4H2I A;  2HY1 A;  2BCD A;  3H69 A;  1G5B A;  2Z06 A;  4OR9 A;  1II7 A;  3D03 A;  4UT2 A;  2BDX A;  2WDF A;  3QG5 C;  4TUI A;  1SU1 A;  3H68 A;  4O43 A;  1QHW A;  1IT6 A;  1JK7 A;  3ZTV A;  4MOY A;  1Z2X A;  1HO5 A;  1WAO 1;  3FLO A;  3H67 A;  3PSO A;  1AUI A;  4I5N C;  4UWQ A;  4FBK A;  5C1V A;  5HPE A;  2WDE A;  1V73 A;  4JA9 A;  3QFM A;  1TCO A;  1S3L A;  4ORB A;  3KBP A;  4LAC C;  2DXN A;  4H2B A;  2HYO A;  2QFP A;  3PSN A;  3K7W C;  2CV9 A;  3H61 A;  2KKN A;  1UTE A;  3N5U A;  3LL8 A;  2A22 A;  3EGG A;  4HD0 A;  2Z1A A;  2HYP A;  4M0V A;  4B2O A;  4UT3 B;  3ZU0 A;  5INB A;  4G9J A;  4JA7 A;  4O5G A;  4V0V A;  2DXL A;  4ZVZ A;  2BQ8 X;  1QFC A;  1FJM A;  4I5L C;  5B8I A;  2P6B A;  3IVD A;  1UF3 A;  3IVE A;  3DW8 C;  3H64 A;  4DSY A;  4Q7F A;  1NNW A;  2XMO A;  4DHL A;  4IL1 A;  2YVT A;  5JPE A;  4LU9 A;  3EGH A;  3FGA C;  3HVQ A;  3RL4 A;  4NZV A;  2NYL C;  3CK2 A;  3RL3 A;  3THO B;  5DNY A;  1T70 A;  3IB8 A;  2ZOA A;  2AHD A;  3IB7 A;  4ORC A;  5JJT A;  2DFJ A;  3QFN A;  3DSD A;  1KBP A;  3E7B A;  4H2F A;  5GTU A;  3DSC A;  1OI8 A;  2QFR A;  2Z72 A;  1XM7 A;  4ORA A;  2IE4 C;  4WWL A;  4XPN A;  2QJC A;  4KBP A;  4KKZ A;  5F3W A;  3JYF A;  3P71 C;  1OID A;  1OIE A;  1S95 A;  5EQV A;  3T1I A;  1W24 A;  1S70 A;  4F0Z A;  3V4Y A;  1S3M A;  4DT2 A;  4TUG A;  1HPU A;  4V0W A;  5J28 A;  2NXF A;  2JOG A;  3H66 A;  2O8A A;  4YKE A;  2WDC A;  4O24 A;  1MF8 A;  2NYM C;  3C9F A;  2WDD A;  3H62 B;  3H60 A;  4ZX2 A;  1Z2W A;  3GVE A;  3THN A;  3QFK A;  1T71 A;  1S3N A;  1U32 A;  1XZW A;  2O8G A;  4H1Y P;  3TGH A;  4FBW A;  5IOH A;  3AV0 A;  3AUZ A;  4MOV A;  4H2G A;  3RL5 A;  1USH A;  3C5W C;  1M63 A;  4O4K A;  5JPF A;  2YEQ A;  4MP0 A;  2IAE C;  1WAR A;  2Q8U A;  4H1S A;  2IE3 C;  4J6O A;  1S8E A;  3E7A A;  2GJU A;  3ICF A;  2USH A;  2NPP C;  4IYP C;  3RQZ A; 
#chains in the Genus database with same CATH homology
 3E0J A;  2R17 A;  3QFO A;  2ZO9 B;  4FCX A;  2ZBM A;  3H63 A;  4FBQ A;  3K7V C;  4LTY A;  1HP1 A;  4V0X A;  4UT3 A;  4H2I A;  2HY1 A;  2BCD A;  3H69 A;  1G5B A;  2Z06 A;  4OR9 A;  1II7 A;  3D03 A;  4UT2 A;  2BDX A;  2WDF A;  3QG5 C;  4TUI A;  1SU1 A;  3H68 A;  4O43 A;  1QHW A;  1IT6 A;  1JK7 A;  3ZTV A;  4MOY A;  1Z2X A;  1HO5 A;  1WAO 1;  3FLO A;  3H67 A;  3PSO A;  1AUI A;  4I5N C;  4UWQ A;  4FBK A;  5C1V A;  5HPE A;  2WDE A;  1V73 A;  4JA9 A;  3QFM A;  1TCO A;  1S3L A;  4ORB A;  3KBP A;  4LAC C;  2DXN A;  4H2B A;  2HYO A;  2QFP A;  3PSN A;  3K7W C;  2CV9 A;  3H61 A;  2KKN A;  1UTE A;  3N5U A;  3LL8 A;  2A22 A;  3EGG A;  4HD0 A;  2Z1A A;  2HYP A;  4M0V A;  4B2O A;  4UT3 B;  3ZU0 A;  5INB A;  4G9J A;  4JA7 A;  4O5G A;  4V0V A;  2DXL A;  4ZVZ A;  2BQ8 X;  1QFC A;  1FJM A;  4I5L C;  5B8I A;  2P6B A;  3IVD A;  1UF3 A;  3IVE A;  3DW8 C;  3H64 A;  4DSY A;  4Q7F A;  1NNW A;  2XMO A;  4DHL A;  4IL1 A;  2YVT A;  5JPE A;  4LU9 A;  3EGH A;  3FGA C;  3HVQ A;  3RL4 A;  4NZV A;  2NYL C;  3CK2 A;  3RL3 A;  3THO B;  5DNY A;  1T70 A;  3IB8 A;  2ZOA A;  2AHD A;  3IB7 A;  4ORC A;  5JJT A;  2DFJ A;  3QFN A;  3DSD A;  1KBP A;  3E7B A;  4H2F A;  5GTU A;  3DSC A;  1OI8 A;  2QFR A;  2Z72 A;  1XM7 A;  4ORA A;  2IE4 C;  4WWL A;  4XPN A;  2QJC A;  4KBP A;  4KKZ A;  5F3W A;  3JYF A;  3P71 C;  1OID A;  1OIE A;  1S95 A;  5EQV A;  3T1I A;  1W24 A;  1S70 A;  4F0Z A;  3V4Y A;  1S3M A;  4DT2 A;  4TUG A;  1HPU A;  4V0W A;  5J28 A;  2NXF A;  2JOG A;  3H66 A;  2O8A A;  4YKE A;  2WDC A;  4O24 A;  1MF8 A;  2NYM C;  3C9F A;  2WDD A;  3H62 B;  3H60 A;  4ZX2 A;  1Z2W A;  3GVE A;  3THN A;  3QFK A;  1T71 A;  1S3N A;  1U32 A;  1XZW A;  2O8G A;  4H1Y P;  3TGH A;  4FBW A;  5IOH A;  3AV0 A;  3AUZ A;  4MOV A;  4H2G A;  3RL5 A;  1USH A;  3C5W C;  1M63 A;  4O4K A;  5JPF A;  2YEQ A;  4MP0 A;  2IAE C;  1WAR A;  2Q8U A;  4H1S A;  2IE3 C;  4J6O A;  1S8E A;  3E7A A;  2GJU A;  3ICF A;  2USH A;  2NPP C;  4IYP C;  3RQZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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