The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
204
|
sequence length |
855
|
structure length |
824
|
Chain Sequence |
MAVQPKETLQLESAAEVGFVRFFQGMPEKPTTTVRLFDRGDAYTAHGEDALLAAREVFKTQGVIKYMGPAGAKNLQSVVLSKMNFESFVKDLLLVRQYRVEVYKNRAGSKENDWYLAYKASPGNLSQFEDILFGNNIGVVGVKMQRQVGVGYVDSIQRKLGLCEFPDNDQFSNLEALLIQIGPKECVLPGGETAGDMGKLRQIIQRGGILITERKKADFSTKDIYQDLNRGKKGEQMNSAVLPEMENQVAVSSLSAVIKFLELLSDDSNFGQFELTTFDFSQYMKLDIAAVRALNLFQTGSQSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAFVEDAELRQTLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQALEKHEGKHQKLLLAVFVTPLTDLRSDFSKFQEMIETTLDMDQVENHEFLVKPSFDPNLSELREIMNDLEKKMQSTLISAARDLGLDPGKQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFSTVDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAQLDAVVSFAHVSNGAPVPYVRPAILEKGQGRIILKASRHACVEVQDEIAFIPNDVYFEKDKQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFCMFATHFHELTALANQIPTVNNLHVTALTTEETLTMLYQVKKGVCDQSFGIHVAELANFPKHVIECAKQKALELEEFQ
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Structure of the Human MutSalpha DNA Lesion Recognition Complex.
pubmed doi rcsb |
| molecule keywords |
5'-D(*GP*AP*AP*CP*CP*GP*CP*GP*GP*GP*CP*TP*AP*GP*G)-3'
|
| molecule tags |
Dna binding protein/dna
|
| source organism |
Homo sapiens
|
| total genus |
204
|
| structure length |
824
|
| sequence length |
855
|
| ec nomenclature | |
| pdb deposition date | 2006-12-12 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF00488 | MutS_V | MutS domain V |
| A | PF01624 | MutS_I | MutS domain I |
| A | PF05188 | MutS_II | MutS domain II |
| A | PF05190 | MutS_IV | MutS family domain IV |
| A | PF05192 | MutS_III | MutS domain III |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Alpha | Orthogonal Bundle | MutS, DNA mismatch repair protein; Chain A, domain 3 | MutS, DNA mismatch repair protein; Chain A, domain 3 | ||
| Mainly Alpha | Orthogonal Bundle | MutS, DNA mismatch repair protein; Chain A, domain 3 | MutS, DNA mismatch repair protein; Chain A, domain 3 | ||
| Alpha Beta | 2-Layer Sandwich | Nucleotidyltransferase; domain 5 | MutS, connector domain | ||
| Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | P-loop containing nucleotide triphosphate hydrolases | ||
| Alpha Beta | 3-Layer(aba) Sandwich | MutS, DNA mismatch repair protein, domain I | DNA repair protein MutS, domain I |
