2ODEB

Crystal structure of the heterodimeric complex of human rgs8 and activated gi alpha 3
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
131
structure length
131
Chain Sequence
STEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
molecule keywords Guanine nucleotide-binding protein G(k) subunit alpha
publication title Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
pubmed doi rcsb
source organism Homo sapiens
total genus 53
structure length 131
sequence length 131
chains with identical sequence D
ec nomenclature
pdb deposition date 2006-12-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 2odeB02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 2odeB01
3NYNA 2V4ZB 3V5WA 2ODEB 1DK8A 2OJ4A 2JNUA 4TNBA 5HE3A 5DO9B 2IHDA 5HE0A 3C7LA 2JM5A 1FQJB 1FQKB 2IHBB 2BV1A 4MK0A 4TNDA 3KRWA 4PNKA 2GTPC 3UZTA 1EZTA 1EMUA 3PSCA 2AF0A 3PVWA 2IK8B 2BCJA 3PVUA 1CMZA 2CRPA 1AGRE 2EBZA 3NYOA 5HE2A 2D9JA 5HE1A 1OMWA 2OWIA 4EKDB 1EZYA 3C7KB 2DLVA 2BT2A 3KRXA 1FQIA 3CIKA
chains in the Genus database with same CATH superfamily
3NYNA 2V4ZB 3V5WA 2ODEB 1DK8A 2OJ4A 2JNUA 4TNBA 5HE3A 5DO9B 2IHDA 3I5QA 5HE0A 3C7LA 2JM5A 1FQJB 1FQKB 2IHBB 2BV1A 4MK0A 4TNDA 3KRWA 4PNKA 4HTEA 2GTPC 3UZTA 1EZTA 1EMUA 3PSCA 2AF0A 3PVWA 2IK8B 3QYFA 2BCJA 5REQB 3PVUA 1CMZA 2CRPA 1AGRE 2EBZA 3NYOA 5HE2A 2D9JA 5HE1A 1OMWA 2OWIA 4EKDB 1EZYA 3C7KB 2DLVA 2BT2A 3KRXA 1FQIA 3CIKA
chains in the Genus database with same CATH topology
3NYNA 2V4ZB 3V5WA 2ODEB 1DK8A 2OJ4A 2JNUA 4TNBA 5HE3A 5DO9B 2IHDA 5HE0A 3C7LA 2JM5A 1FQJB 1FQKB 2IHBB 2BV1A 4MK0A 4TNDA 3KRWA 4PNKA 2GTPC 3UZTA 1EZTA 1EMUA 3PSCA 2AF0A 3PVWA 2IK8B 3QYFA 2BCJA 5REQB 3PVUA 1CMZA 2CRPA 1AGRE 2EBZA 3NYOA 5HE2A 2D9JA 5HE1A 1OMWA 2OWIA 4EKDB 1EZYA 3C7KB 2DLVA 2BT2A 3KRXA 1FQIA 3CIKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NYN A;  2V4Z B;  3V5W A;  2ODE B;  1DK8 A;  2OJ4 A;  2JNU A;  4TNB A;  5HE3 A;  5DO9 B;  2IHD A;  5HE0 A;  3C7L A;  2JM5 A;  1FQJ B;  1FQK B;  2IHB B;  2BV1 A;  4MK0 A;  4TND A;  3KRW A;  4PNK A;  2GTP C;  3UZT A;  1EZT A;  1EMU A;  3PSC A;  2AF0 A;  3PVW A;  2IK8 B;  2BCJ A;  3PVU A;  1CMZ A;  2CRP A;  1AGR E;  2EBZ A;  3NYO A;  5HE2 A;  2D9J A;  5HE1 A;  1OMW A;  2OWI A;  4EKD B;  1EZY A;  3C7K B;  2DLV A;  2BT2 A;  3KRX A;  1FQI A;  3CIK A; 
#chains in the Genus database with same CATH topology
 3NYN A;  2V4Z B;  3V5W A;  2ODE B;  1DK8 A;  2OJ4 A;  2JNU A;  4TNB A;  5HE3 A;  5DO9 B;  2IHD A;  3I5Q A;  5HE0 A;  3C7L A;  2JM5 A;  1FQJ B;  1FQK B;  2IHB B;  2BV1 A;  4MK0 A;  4TND A;  3KRW A;  4PNK A;  4HTE A;  2GTP C;  3UZT A;  1EZT A;  1EMU A;  3PSC A;  2AF0 A;  3PVW A;  2IK8 B;  3QYF A;  2BCJ A;  5REQ B;  3PVU A;  1CMZ A;  2CRP A;  1AGR E;  2EBZ A;  3NYO A;  5HE2 A;  2D9J A;  5HE1 A;  1OMW A;  2OWI A;  4EKD B;  1EZY A;  3C7K B;  2DLV A;  2BT2 A;  3KRX A;  1FQI A;  3CIK A; 
#chains in the Genus database with same CATH homology
 3NYN A;  2V4Z B;  3V5W A;  2ODE B;  1DK8 A;  2OJ4 A;  2JNU A;  4TNB A;  5HE3 A;  5DO9 B;  2IHD A;  5HE0 A;  3C7L A;  2JM5 A;  1FQJ B;  1FQK B;  2IHB B;  2BV1 A;  4MK0 A;  4TND A;  3KRW A;  4PNK A;  2GTP C;  3UZT A;  1EZT A;  1EMU A;  3PSC A;  2AF0 A;  3PVW A;  2IK8 B;  3QYF A;  2BCJ A;  5REQ B;  3PVU A;  1CMZ A;  2CRP A;  1AGR E;  2EBZ A;  3NYO A;  5HE2 A;  2D9J A;  5HE1 A;  1OMW A;  2OWI A;  4EKD B;  1EZY A;  3C7K B;  2DLV A;  2BT2 A;  3KRX A;  1FQI A;  3CIK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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