2OJ4A

Crystal structure of rgs3 rgs domain
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
127
structure length
127
Chain Sequence
SEEALKWGESLEKLLVHKYGLAVFQAFLRTEFSEENLEFWLACEDFKKVKSQSKMASKAKKIFAEYIAIQACKEVNLDSYTREHTKDNLQSVTRGCFDLAQKRIFGLMEKDSYPRFLRSDLYLDLIN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title 14-3-3 protein interacts with and affects the structure of RGS domain of regulator of G protein signaling 3 (RGS3).
pubmed doi rcsb
molecule tags Signaling protein inhibitor
source organism Homo sapiens
molecule keywords Regulator of G-protein signaling 3
total genus 50
structure length 127
sequence length 127
ec nomenclature
pdb deposition date 2007-01-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 2oj4A02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 2oj4A01
4TNBA 2AF0A 4EKDB 4PNKA 1DK8A 2EBZA 3KRWA 3NYNA 2IHBB 3PSCA 2JM5A 2JNUA 3PVWA 3UZTA 3NYOA 3KRXA 1CMZA 2D9JA 2BT2A 2BV1A 1FQJB 1EZTA 3C7LA 2IHDA 4TNDA 2OWIA 1OMWA 1EMUA 5HE2A 5DO9B 5HE0A 5HE3A 3CIKA 1FQIA 2BCJA 3V5WA 1AGRE 3PVUA 2IK8B 2ODEB 4MK0A 1EZYA 2OJ4A 3C7KB 2GTPC 2V4ZB 5HE1A 2DLVA 2CRPA 1FQKB
chains in the Genus database with same CATH superfamily
4TNBA 2AF0A 4EKDB 4PNKA 1DK8A 2EBZA 3KRWA 3NYNA 2IHBB 3PSCA 2JM5A 3QYFA 2JNUA 3PVWA 3UZTA 5REQB 3I5QA 3NYOA 3KRXA 1CMZA 2D9JA 2BT2A 2BV1A 4HTEA 1FQJB 1EZTA 3C7LA 2IHDA 4TNDA 2OWIA 1OMWA 1EMUA 5HE2A 5DO9B 5HE0A 5HE3A 3CIKA 1FQIA 2BCJA 3V5WA 1AGRE 3PVUA 2IK8B 2ODEB 4MK0A 1EZYA 2OJ4A 3C7KB 2GTPC 2V4ZB 5HE1A 2DLVA 2CRPA 1FQKB
chains in the Genus database with same CATH topology
4TNBA 2AF0A 4EKDB 4PNKA 1DK8A 2EBZA 3KRWA 3NYNA 2IHBB 3PSCA 2JM5A 3QYFA 2JNUA 3PVWA 3UZTA 5REQB 3NYOA 3KRXA 1CMZA 2D9JA 2BT2A 2BV1A 1FQJB 1EZTA 3C7LA 2IHDA 4TNDA 2OWIA 1OMWA 1EMUA 5HE2A 5DO9B 5HE0A 5HE3A 3CIKA 1FQIA 2BCJA 3V5WA 1AGRE 3PVUA 2IK8B 2ODEB 4MK0A 1EZYA 2OJ4A 3C7KB 2GTPC 2V4ZB 5HE1A 2DLVA 2CRPA 1FQKB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4TNB A;  2AF0 A;  4EKD B;  4PNK A;  1DK8 A;  2EBZ A;  3KRW A;  3NYN A;  2IHB B;  3PSC A;  2JM5 A;  2JNU A;  3PVW A;  3UZT A;  3NYO A;  3KRX A;  1CMZ A;  2D9J A;  2BT2 A;  2BV1 A;  1FQJ B;  1EZT A;  3C7L A;  2IHD A;  4TND A;  2OWI A;  1OMW A;  1EMU A;  5HE2 A;  5DO9 B;  5HE0 A;  5HE3 A;  3CIK A;  1FQI A;  2BCJ A;  3V5W A;  1AGR E;  3PVU A;  2IK8 B;  2ODE B;  4MK0 A;  1EZY A;  2OJ4 A;  3C7K B;  2GTP C;  2V4Z B;  5HE1 A;  2DLV A;  2CRP A;  1FQK B; 
#chains in the Genus database with same CATH topology
 4TNB A;  2AF0 A;  4EKD B;  4PNK A;  1DK8 A;  2EBZ A;  3KRW A;  3NYN A;  2IHB B;  3PSC A;  2JM5 A;  3QYF A;  2JNU A;  3PVW A;  3UZT A;  5REQ B;  3I5Q A;  3NYO A;  3KRX A;  1CMZ A;  2D9J A;  2BT2 A;  2BV1 A;  4HTE A;  1FQJ B;  1EZT A;  3C7L A;  2IHD A;  4TND A;  2OWI A;  1OMW A;  1EMU A;  5HE2 A;  5DO9 B;  5HE0 A;  5HE3 A;  3CIK A;  1FQI A;  2BCJ A;  3V5W A;  1AGR E;  3PVU A;  2IK8 B;  2ODE B;  4MK0 A;  1EZY A;  2OJ4 A;  3C7K B;  2GTP C;  2V4Z B;  5HE1 A;  2DLV A;  2CRP A;  1FQK B; 
#chains in the Genus database with same CATH homology
 4TNB A;  2AF0 A;  4EKD B;  4PNK A;  1DK8 A;  2EBZ A;  3KRW A;  3NYN A;  2IHB B;  3PSC A;  2JM5 A;  3QYF A;  2JNU A;  3PVW A;  3UZT A;  5REQ B;  3NYO A;  3KRX A;  1CMZ A;  2D9J A;  2BT2 A;  2BV1 A;  1FQJ B;  1EZT A;  3C7L A;  2IHD A;  4TND A;  2OWI A;  1OMW A;  1EMU A;  5HE2 A;  5DO9 B;  5HE0 A;  5HE3 A;  3CIK A;  1FQI A;  2BCJ A;  3V5W A;  1AGR E;  3PVU A;  2IK8 B;  2ODE B;  4MK0 A;  1EZY A;  2OJ4 A;  3C7K B;  2GTP C;  2V4Z B;  5HE1 A;  2DLV A;  2CRP A;  1FQK B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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