2OJ4A

Crystal structure of rgs3 rgs domain
Total Genus 50
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
127
structure length
127
Chain Sequence
SEEALKWGESLEKLLVHKYGLAVFQAFLRTEFSEENLEFWLACEDFKKVKSQSKMASKAKKIFAEYIAIQACKEVNLDSYTREHTKDNLQSVTRGCFDLAQKRIFGLMEKDSYPRFLRSDLYLDLIN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Signaling protein inhibitor
molecule keywords Regulator of G-protein signaling 3
publication title 14-3-3 protein interacts with and affects the structure of RGS domain of regulator of G protein signaling 3 (RGS3).
pubmed doi rcsb
source organism Homo sapiens
total genus 50
structure length 127
sequence length 127
ec nomenclature
pdb deposition date 2007-01-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 2oj4A02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 2oj4A01
3KRXA 2IHDA 4TNDA 1FQIA 3PVWA 2V4ZB 1DK8A 2D9JA 2IHBB 3KRWA 2OWIA 1EMUA 4EKDB 2JNUA 3C7KB 3UZTA 1CMZA 3NYOA 1EZYA 5HE0A 5HE1A 4TNBA 2OJ4A 2IK8B 2JM5A 2BV1A 5HE3A 5HE2A 2BCJA 1FQKB 5DO9B 1OMWA 2EBZA 2GTPC 3CIKA 3NYNA 1EZTA 1FQJB 4MK0A 2AF0A 2CRPA 2ODEB 3V5WA 4PNKA 2DLVA 1AGRE 3PVUA 2BT2A 3PSCA 3C7LA
chains in the Genus database with same CATH superfamily
3KRXA 2IHDA 4TNDA 1FQIA 3PVWA 2V4ZB 1DK8A 2D9JA 2IHBB 3KRWA 2OWIA 1EMUA 4EKDB 2JNUA 3C7KB 3UZTA 1CMZA 3I5QA 3NYOA 1EZYA 5HE0A 5HE1A 4TNBA 2OJ4A 2IK8B 2JM5A 5REQB 2BV1A 5HE3A 5HE2A 2BCJA 1FQKB 4HTEA 1OMWA 2EBZA 2GTPC 5DO9B 3CIKA 3NYNA 1EZTA 1FQJB 4MK0A 2AF0A 2CRPA 2ODEB 3V5WA 4PNKA 2DLVA 1AGRE 3PVUA 2BT2A 3PSCA 3C7LA 3QYFA
chains in the Genus database with same CATH topology
3KRXA 2IHDA 4TNDA 1FQIA 3PVWA 2V4ZB 1DK8A 2D9JA 2IHBB 3KRWA 2OWIA 1EMUA 4EKDB 2JNUA 3C7KB 3UZTA 1CMZA 3NYOA 1EZYA 5HE0A 5HE1A 4TNBA 2OJ4A 2IK8B 2JM5A 5REQB 2BV1A 5HE3A 5HE2A 2BCJA 1FQKB 5DO9B 1OMWA 2EBZA 2GTPC 3CIKA 3NYNA 1EZTA 1FQJB 4MK0A 2AF0A 2CRPA 2ODEB 3V5WA 4PNKA 2DLVA 1AGRE 3PVUA 2BT2A 3PSCA 3C7LA 3QYFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KRX A;  2IHD A;  4TND A;  1FQI A;  3PVW A;  2V4Z B;  1DK8 A;  2D9J A;  2IHB B;  3KRW A;  2OWI A;  1EMU A;  4EKD B;  2JNU A;  3C7K B;  3UZT A;  1CMZ A;  3NYO A;  1EZY A;  5HE0 A;  5HE1 A;  4TNB A;  2OJ4 A;  2IK8 B;  2JM5 A;  2BV1 A;  5HE3 A;  5HE2 A;  2BCJ A;  1FQK B;  5DO9 B;  1OMW A;  2EBZ A;  2GTP C;  3CIK A;  3NYN A;  1EZT A;  1FQJ B;  4MK0 A;  2AF0 A;  2CRP A;  2ODE B;  3V5W A;  4PNK A;  2DLV A;  1AGR E;  3PVU A;  2BT2 A;  3PSC A;  3C7L A; 
#chains in the Genus database with same CATH topology
 3KRX A;  2IHD A;  4TND A;  1FQI A;  3PVW A;  2V4Z B;  1DK8 A;  2D9J A;  2IHB B;  3KRW A;  2OWI A;  1EMU A;  4EKD B;  2JNU A;  3C7K B;  3UZT A;  1CMZ A;  3I5Q A;  3NYO A;  1EZY A;  5HE0 A;  5HE1 A;  4TNB A;  2OJ4 A;  2IK8 B;  2JM5 A;  5REQ B;  2BV1 A;  5HE3 A;  5HE2 A;  2BCJ A;  1FQK B;  4HTE A;  1OMW A;  2EBZ A;  2GTP C;  5DO9 B;  3CIK A;  3NYN A;  1EZT A;  1FQJ B;  4MK0 A;  2AF0 A;  2CRP A;  2ODE B;  3V5W A;  4PNK A;  2DLV A;  1AGR E;  3PVU A;  2BT2 A;  3PSC A;  3C7L A;  3QYF A; 
#chains in the Genus database with same CATH homology
 3KRX A;  2IHD A;  4TND A;  1FQI A;  3PVW A;  2V4Z B;  1DK8 A;  2D9J A;  2IHB B;  3KRW A;  2OWI A;  1EMU A;  4EKD B;  2JNU A;  3C7K B;  3UZT A;  1CMZ A;  3NYO A;  1EZY A;  5HE0 A;  5HE1 A;  4TNB A;  2OJ4 A;  2IK8 B;  2JM5 A;  5REQ B;  2BV1 A;  5HE3 A;  5HE2 A;  2BCJ A;  1FQK B;  5DO9 B;  1OMW A;  2EBZ A;  2GTP C;  3CIK A;  3NYN A;  1EZT A;  1FQJ B;  4MK0 A;  2AF0 A;  2CRP A;  2ODE B;  3V5W A;  4PNK A;  2DLV A;  1AGR E;  3PVU A;  2BT2 A;  3PSC A;  3C7L A;  3QYF A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...