2OPMA

Human farnesyl diphosphate synthase complexed with bisphosphonate bph-461
Total Genus 132
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
132
sequence length
338
structure length
336
Chain Sequence
EKQDFVQHFSQIVRVLTEDEHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Farnesyl pyrophosphate synthetase (FPP synthetase) (FPS) (Fa
publication title Lipophilic bisphosphonates as dual farnesyl/geranylgeranyl diphosphate synthase inhibitors: an X-ray and NMR investigation.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 132
structure length 336
sequence length 338
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2007-01-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 2opmA00
3WEKA 4KWDA 3WCEA 4RYPA 4LOBA 2ZEUA 2P1CA 1YYSA 1JFAA 3WEGA 3V1VA 3NPKA 3TC1A 5A0JA 2Z4ZA 2F89F 2F8CF 4XQRF 5E8LA 4KQUA 4OMGA 3VJDA 3RMGA 1V4HA 2J5CA 1EZFA 3WCGA 5B0KA 1RQIA 2AZJA 3TS7A 1JFGA 1KIYA 5AYPA 5ERNA 3M9UA 4OKZA 1RTRA 3WCJA 5EATA 2F9KF 4RXEA 2RAHA 2ZY1A 3IPIA 4KQSA 5IVGA 3MZVA 4JZXA 4LLTA 5AELA 4KVWA 5ILZA 5JV2F 5B02A 2AZKA 3TFNA 4LA5A 5E8HA 4RNQA 3AQBB 4EA1A 4JXYA 4H5DF 2VF6A 4KVIA 2F7MF 1N20A 4GP2A 3MAVA 3B7LA 4JVJF 3DYHA 5DJPF 5DW7A 5I1UA 4N9UA 5C05A 4KVDA 4QPFA 3ASXA 3LMDA 2PS4A 3PH7A 3LG5A 3WCHA 2OPMA 3WEHA 3G4FA 3NPRA 3P41A 5DGMF 5B0IA 5DHKA 3SDTA 2Z78A 3TFVA 2OGDA 4HD1A 5IMPA 3SAEA 2Q9ZA 4LZCA 3ZMBA 3ICZA 3WSAA 5JUZF 4WK5A 4RXDA 5IMNA 3VJ8A 4OMHA 4MC8A 2AELA 3ICNA 5ILDA 1WL3A 3CP6A 3N3DA 2E8VA 1KIZA 3KRAA 1WL2A 4MC3A 1PS1A 1UBVA 2PS7A 4LXWA 5IK0A 3WCDA 3KRFA 4RXCA 3LLWA 3ADZA 4LFGA 3N5JF 5B0JA 3AQ0A 4L2XF 4DXJA 3KROB 4N1ZF 4KQ5A 3AE0A 3N6KF 2Z7HA 3QKCA 3RBMA 2ZCQA 5IN8A 4KFAA 1N24A 5B0MA 3WEFA 5IL3A 3LDWA 4EA2A 2E8TA 3LOMA 1N22A 3ICKA 3WCCA 3KBKA 4LLSA 4H5EF 2AETA 1V4IA 3Q30A 3Q2ZA 4E9UA 4DHDA 4KPDA 3CKEA 3ZL6A 3G4DA 5HN8A 3WJKA 3APZA 4LIXA 3LGZB 3KRCA 3WJOA 5IK9A 1N1ZA 2Z52A 4LUUA 5IKHA 5B01A 3P8RA 5ERMA 1FPSA 4UMJA 3ZCDA 3ICMA 3S4JA 2Q9YA 3OYRA 1YHKA 4NFJF 2Z4YA 3VJCA 3N1WF 3CC9A 5DGSF 3ZOUA 3N5HF 1VG2A 3M02A 1YYUA 2OA6A 3N46F 2E8WA 5ILYA 3N3LF 4NFIF 5ER8A 5ILKA 4LFVF 4JXNA 1YYQA 1VG3A 4DZWA 5DJRF 4PVXF 3UCAA 3NF2A 3WEJA 4LZ3A 4NKFA 3V1XA 5JV0F 5EASA 2ZCRA 2Z50A 2PS6A 4F6XA 5EROA 1HM7A 3BNYA 2Z4VA 1UBWA 5A0KA 1ZW5A 2FTZA 3OABA 2OPNA 2Q58A 1RQJA 3M0GA 4MC0A 3OABB 1YJ4A 4XQTF 5E8KA 4GAXA 3WE9A 3KB9A 2ONHA 3WCIA 2E91A 5IL8A 1DI1A 3WJNA 3SDUA 3WCBA 4XQSF 3VJAA 5ILIA 3BNXA 3RYWA 4P0WA 3ZMCA 3M00A 1N23A 1YHMA 3PYBA 1WY0A 3KRAB 3SDRA 5JV1F 3EGTA 3OACA 3PYAA 3PKOA 3OACB 2E90A 3KRFB 5IKAA 3LZ9A 4JYXA 3KRPA 3V66A 1UBXA 4GA3A 2PS5A 3Q2QA 5B00A 4DWBA 4LZ0A 2Z4XA 4LPGF 1HXCA 5EAUA 2E94A 2E92A 4KKMA 1VG7A 1N21A 1YHLA 5CG6A 5CG5A 2DH4A 5HN7A 3VJEA 1HXAA 2ZCSA 2E4OA 2Z4WA 5DJVF 4KK2A 3P8LA 5ILHA 3W7FA 3LK5A 3PDEA 4FJQA 2H8OA 4JZBA 2F92F 3WSBA 4DWGA 1YYRA 3ID0A 1HXGA 3KRCB 2Z7IA 3LEEA 4OKMA 3SDVA 3WEIA 1WL1A 2E95A 2F8ZF 3WCFA 3WCAA 4KPJA 4F6VA 4NKEA 1WMWA 5HNAA 3WC9A 1HM4A 1WKZA 3DYGA 4DI5A 5DGNF 1VG4A 4GP1A 3LSNA 3SDQA 4OGUA 4E9ZA 2AEKA 5A0IA 1V4KA 5DHIA 3N45F 3N0GA 5DIQF 5HN9A 1V4JA 2Q80A 4H5CF 1HX9A 4NG6A 4NFKF 2J1OA 3WCLA 4F62A 2ONGA 1UBYA 3N0FA 2E8XA 3EZ3A 2O1OA 2PS8A 1VG6A 1YYTA 5KSXF 5IK6A 3S9VA 4DEMF 2E93A 1DGPA 2FORA 4LA6A 3TFPA 4NUAA 4ZQ8A 3WCMA 3LJIA 5ILJA 3M01A 4E1EA 1YV5A 4PVYF 4Q23A 2E8UA 3IBAA 1V4EA 4LTVA 3VJ9A 4LPHF 5IMIA 5AFXA 1WL0A 4QXSF 4FP4A 3P5PA 5B0LA 3NRIA 5DZ2A 3VJBA 4K10A 3LVSA 2I19A 2ZCOA 4P0VA 3QQVA 3KRPB 1N1BA 5IM1A 5AHUB 4KVYA 5JA0F 2J1PA 2ZEVA 3ACYA 3LGKA 2F94F 4LTZA 3N49F 5B03A 3N1VF 3KROA 4KUXA 3Q1OA 3P5RA 4RXAA 4P0XA 3AQCB 3EFQA 4EA0A 3DYFA 2QISA 5H9DA 2AZLA 3ACXA 4LFEA 3RYEA 3ACWA 2EWGA 1YQ7A
chains in the Genus database with same CATH superfamily
3WEKA 4KWDA 3WCEA 4RYPA 4LOBA 2ZEUA 2P1CA 1YYSA 1JFAA 3WEGA 3V1VA 3NPKA 3TC1A 5A0JA 2Z4ZA 2F89F 2F8CF 4XQRF 5E8LA 4KQUA 4OMGA 3VJDA 3RMGA 1V4HA 2J5CA 1EZFA 3WCGA 5B0KA 1RQIA 2AZJA 3TS7A 1JFGA 1KIYA 5AYPA 5ERNA 3M9UA 4OKZA 1RTRA 3WCJA 5EATA 2F9KF 4RXEA 2RAHA 2ZY1A 3IPIA 4KQSA 5IVGA 3MZVA 4JZXA 4LLTA 5AELA 4KVWA 5ILZA 5JV2F 5B02A 2AZKA 3TFNA 4LA5A 5E8HA 4RNQA 3AQBB 4EA1A 4JXYA 4H5DF 2VF6A 4KVIA 2F7MF 1N20A 4GP2A 3MAVA 3B7LA 4JVJF 3DYHA 5DJPF 5DW7A 5I1UA 4N9UA 5C05A 4KVDA 4QPFA 3ASXA 3LMDA 2PS4A 3PH7A 3LG5A 3WCHA 2OPMA 3WEHA 3G4FA 3NPRA 3P41A 5DGMF 5B0IA 5DHKA 3SDTA 2Z78A 3TFVA 2OGDA 4HD1A 5IMPA 3SAEA 2Q9ZA 4LZCA 3ZMBA 3ICZA 3WSAA 5JUZF 4WK5A 4RXDA 5IMNA 3VJ8A 4OMHA 4MC8A 2AELA 3ICNA 5ILDA 1WL3A 3CP6A 3N3DA 2E8VA 1KIZA 3KRAA 1WL2A 4MC3A 1PS1A 1UBVA 2PS7A 4LXWA 5IK0A 3WCDA 3KRFA 4RXCA 3LLWA 3ADZA 4LFGA 3N5JF 5B0JA 3AQ0A 4L2XF 4DXJA 3KROB 4N1ZF 4KQ5A 3AE0A 3N6KF 2Z7HA 3QKCA 3RBMA 2ZCQA 5IN8A 4KFAA 1N24A 5B0MA 3WEFA 5IL3A 3LDWA 4EA2A 2E8TA 3LOMA 1N22A 3ICKA 3WCCA 3KBKA 4LLSA 4H5EF 2AETA 1V4IA 3Q30A 3Q2ZA 4E9UA 4DHDA 4KPDA 3CKEA 3ZL6A 3G4DA 5HN8A 3WJKA 3APZA 4LIXA 3LGZB 3KRCA 3WJOA 5IK9A 1N1ZA 2Z52A 4LUUA 5IKHA 5B01A 3P8RA 5ERMA 1FPSA 4UMJA 3ZCDA 3ICMA 3S4JA 2Q9YA 3OYRA 1YHKA 4NFJF 2Z4YA 3VJCA 3N1WF 3CC9A 5DGSF 3ZOUA 3N5HF 1VG2A 3M02A 1YYUA 2OA6A 3N46F 2E8WA 5ILYA 3N3LF 4NFIF 5ER8A 5ILKA 4LFVF 4JXNA 1YYQA 1VG3A 4DZWA 5DJRF 4PVXF 3UCAA 3NF2A 3WEJA 4LZ3A 4NKFA 3V1XA 5JV0F 5EASA 2ZCRA 2Z50A 2PS6A 4F6XA 5EROA 1HM7A 3BNYA 2Z4VA 1UBWA 5A0KA 1ZW5A 2FTZA 3OABA 2OPNA 2Q58A 1RQJA 3M0GA 4MC0A 3OABB 1YJ4A 4XQTF 5E8KA 4GAXA 3WE9A 3KB9A 2ONHA 3WCIA 2E91A 5IL8A 1DI1A 3WJNA 3SDUA 3WCBA 4XQSF 3VJAA 5ILIA 3BNXA 3RYWA 4P0WA 3ZMCA 3M00A 1N23A 1YHMA 3PYBA 1WY0A 3KRAB 3SDRA 5JV1F 3EGTA 3OACA 3PYAA 3PKOA 3OACB 2E90A 3KRFB 5IKAA 3LZ9A 4JYXA 3KRPA 3V66A 1UBXA 4GA3A 2PS5A 3Q2QA 5B00A 4DWBA 4LZ0A 2Z4XA 4LPGF 1HXCA 5EAUA 2E94A 2E92A 4KKMA 1VG7A 1N21A 1YHLA 5CG6A 5CG5A 2DH4A 5HN7A 3VJEA 1HXAA 2ZCSA 2E4OA 2Z4WA 5DJVF 4KK2A 3P8LA 5ILHA 3W7FA 3LK5A 3PDEA 4FJQA 2H8OA 4JZBA 2F92F 3WSBA 4DWGA 1YYRA 3ID0A 1HXGA 3KRCB 2Z7IA 3LEEA 4OKMA 3SDVA 3WEIA 1WL1A 2E95A 2F8ZF 3WCFA 3WCAA 4KPJA 4F6VA 4NKEA 1WMWA 5HNAA 3WC9A 1HM4A 1WKZA 3DYGA 4DI5A 5DGNF 1VG4A 4GP1A 3LSNA 3SDQA 4OGUA 4E9ZA 2AEKA 5A0IA 1V4KA 5DHIA 3N45F 3N0GA 5DIQF 5HN9A 1V4JA 2Q80A 4H5CF 1HX9A 4NG6A 4NFKF 2J1OA 3WCLA 4F62A 2ONGA 1UBYA 3N0FA 2E8XA 3EZ3A 2O1OA 2PS8A 1VG6A 1YYTA 5KSXF 5IK6A 3S9VA 4DEMF 2E93A 1DGPA 2FORA 4LA6A 3TFPA 4NUAA 4ZQ8A 3WCMA 3LJIA 5ILJA 3M01A 4E1EA 1YV5A 4PVYF 4Q23A 2E8UA 3IBAA 1V4EA 4LTVA 3VJ9A 4LPHF 5IMIA 5AFXA 1WL0A 4QXSF 4FP4A 3P5PA 5B0LA 3NRIA 5DZ2A 3VJBA 4K10A 3LVSA 2I19A 2ZCOA 4P0VA 3QQVA 3KRPB 1N1BA 5IM1A 5AHUB 4KVYA 5JA0F 2J1PA 2ZEVA 3ACYA 3LGKA 2F94F 4LTZA 3N49F 5B03A 3N1VF 3KROA 4KUXA 3Q1OA 3P5RA 4RXAA 4P0XA 3AQCB 3EFQA 4EA0A 3DYFA 2QISA 5H9DA 2AZLA 3ACXA 4LFEA 3RYEA 3ACWA 2EWGA 1YQ7A
chains in the Genus database with same CATH topology
3WEKA 4KWDA 3WCEA 4RYPA 4LOBA 2ZEUA 2P1CA 1YYSA 1JFAA 3WEGA 3V1VA 3NPKA 3TC1A 5A0JA 2Z4ZA 2F89F 2F8CF 4XQRF 5E8LA 4KQUA 4OMGA 3VJDA 3RMGA 1V4HA 2J5CA 1EZFA 3WCGA 5B0KA 1RQIA 2AZJA 3TS7A 1JFGA 1KIYA 5AYPA 5ERNA 3M9UA 4OKZA 1RTRA 3WCJA 5EATA 2F9KF 4RXEA 2RAHA 2ZY1A 3IPIA 4KQSA 5IVGA 3MZVA 4JZXA 4LLTA 5AELA 4KVWA 5ILZA 5JV2F 5B02A 2AZKA 3TFNA 4LA5A 5E8HA 4RNQA 3AQBB 4EA1A 4JXYA 4H5DF 2VF6A 4KVIA 2F7MF 1N20A 4GP2A 3MAVA 3B7LA 4JVJF 3DYHA 5DJPF 5DW7A 5I1UA 4N9UA 5C05A 4KVDA 4QPFA 3ASXA 3LMDA 2PS4A 3PH7A 3LG5A 3WCHA 2OPMA 3WEHA 3G4FA 3NPRA 3P41A 5DGMF 5B0IA 5DHKA 3SDTA 2Z78A 3TFVA 2OGDA 4HD1A 5IMPA 3SAEA 2Q9ZA 4LZCA 3ZMBA 3ICZA 3WSAA 5JUZF 4WK5A 4RXDA 5IMNA 3VJ8A 4OMHA 4MC8A 2AELA 3ICNA 5ILDA 1WL3A 3CP6A 3N3DA 2E8VA 1KIZA 3KRAA 1WL2A 4MC3A 1PS1A 1UBVA 2PS7A 4LXWA 5IK0A 3WCDA 3KRFA 4RXCA 3LLWA 3ADZA 4LFGA 3N5JF 5B0JA 3AQ0A 4L2XF 4DXJA 3KROB 4N1ZF 4KQ5A 3AE0A 3N6KF 2Z7HA 3QKCA 3RBMA 2ZCQA 5IN8A 4KFAA 1N24A 5B0MA 3WEFA 5IL3A 3LDWA 4EA2A 2E8TA 3LOMA 1N22A 3ICKA 3WCCA 3KBKA 4LLSA 4H5EF 2AETA 1V4IA 3Q30A 3Q2ZA 4E9UA 4DHDA 4KPDA 3CKEA 3ZL6A 3G4DA 5HN8A 3WJKA 3APZA 4LIXA 3LGZB 3KRCA 3WJOA 5IK9A 1N1ZA 2Z52A 4LUUA 5IKHA 5B01A 3P8RA 5ERMA 1FPSA 4UMJA 3ZCDA 3ICMA 3S4JA 2Q9YA 3OYRA 1YHKA 4NFJF 2Z4YA 3VJCA 3N1WF 3CC9A 5DGSF 3ZOUA 3N5HF 1VG2A 3M02A 1YYUA 2OA6A 3N46F 2E8WA 5ILYA 3N3LF 4NFIF 5ER8A 5ILKA 4LFVF 4JXNA 1YYQA 1VG3A 4DZWA 5DJRF 4PVXF 3UCAA 3NF2A 3WEJA 4LZ3A 4NKFA 3V1XA 5JV0F 5EASA 2ZCRA 2Z50A 2PS6A 4F6XA 5EROA 1HM7A 3BNYA 2Z4VA 1UBWA 5A0KA 1ZW5A 2FTZA 3OABA 2OPNA 2Q58A 1RQJA 3M0GA 4MC0A 3OABB 1YJ4A 4XQTF 5E8KA 4GAXA 3WE9A 3KB9A 2ONHA 3WCIA 2E91A 5IL8A 1DI1A 3WJNA 3SDUA 3WCBA 4XQSF 3VJAA 5ILIA 3BNXA 3RYWA 4P0WA 3ZMCA 3M00A 1N23A 1YHMA 3PYBA 1WY0A 3KRAB 3SDRA 5JV1F 3EGTA 3OACA 3PYAA 3PKOA 3OACB 2E90A 3KRFB 5IKAA 3LZ9A 4JYXA 3KRPA 3V66A 1UBXA 4GA3A 2PS5A 3Q2QA 5B00A 4DWBA 4LZ0A 2Z4XA 4LPGF 1HXCA 5EAUA 2E94A 2E92A 4KKMA 1VG7A 1N21A 1YHLA 5CG6A 5CG5A 2DH4A 5HN7A 3VJEA 1HXAA 2ZCSA 2E4OA 2Z4WA 5DJVF 4KK2A 3P8LA 5ILHA 3W7FA 3LK5A 3PDEA 4FJQA 2H8OA 4JZBA 2F92F 3WSBA 4DWGA 1YYRA 3ID0A 1HXGA 3KRCB 2Z7IA 3LEEA 4OKMA 3SDVA 3WEIA 1WL1A 2E95A 2F8ZF 3WCFA 3WCAA 4KPJA 4F6VA 4NKEA 1WMWA 5HNAA 3WC9A 1HM4A 1WKZA 3DYGA 4DI5A 5DGNF 1VG4A 4GP1A 3LSNA 3SDQA 4OGUA 4E9ZA 2AEKA 5A0IA 1V4KA 5DHIA 3N45F 3N0GA 5DIQF 5HN9A 1V4JA 2Q80A 4H5CF 1HX9A 4NG6A 4NFKF 2J1OA 3WCLA 4F62A 2ONGA 1UBYA 3N0FA 2E8XA 3EZ3A 2O1OA 2PS8A 1VG6A 1YYTA 5KSXF 5IK6A 3S9VA 4DEMF 2E93A 1DGPA 2FORA 4LA6A 3TFPA 4NUAA 4ZQ8A 3WCMA 3LJIA 5ILJA 3M01A 4E1EA 1YV5A 4PVYF 4Q23A 2E8UA 3IBAA 1V4EA 4LTVA 3VJ9A 4LPHF 5IMIA 5AFXA 1WL0A 4QXSF 4FP4A 3P5PA 5B0LA 3NRIA 5DZ2A 3VJBA 4K10A 3LVSA 2I19A 2ZCOA 4P0VA 3QQVA 3KRPB 1N1BA 5IM1A 5AHUB 4KVYA 5JA0F 2J1PA 2ZEVA 3ACYA 3LGKA 2F94F 4LTZA 3N49F 5B03A 3N1VF 3KROA 4KUXA 3Q1OA 3P5RA 4RXAA 4P0XA 3AQCB 3EFQA 4EA0A 3DYFA 2QISA 5H9DA 2AZLA 3ACXA 4LFEA 3RYEA 3ACWA 2EWGA 1YQ7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3WEK A;  4KWD A;  3WCE A;  4RYP A;  4LOB A;  2ZEU A;  2P1C A;  1YYS A;  1JFA A;  3WEG A;  3V1V A;  3NPK A;  3TC1 A;  5A0J A;  2Z4Z A;  2F89 F;  2F8C F;  4XQR F;  5E8L A;  4KQU A;  4OMG A;  3VJD A;  3RMG A;  1V4H A;  2J5C A;  1EZF A;  3WCG A;  5B0K A;  1RQI A;  2AZJ A;  3TS7 A;  1JFG A;  1KIY A;  5AYP A;  5ERN A;  3M9U A;  4OKZ A;  1RTR A;  3WCJ A;  5EAT A;  2F9K F;  4RXE A;  2RAH A;  2ZY1 A;  3IPI A;  4KQS A;  5IVG A;  3MZV A;  4JZX A;  4LLT A;  5AEL A;  4KVW A;  5ILZ A;  5JV2 F;  5B02 A;  2AZK A;  3TFN A;  4LA5 A;  5E8H A;  4RNQ A;  3AQB B;  4EA1 A;  4JXY A;  4H5D F;  2VF6 A;  4KVI A;  2F7M F;  1N20 A;  4GP2 A;  3MAV A;  3B7L A;  4JVJ F;  3DYH A;  5DJP F;  5DW7 A;  5I1U A;  4N9U A;  5C05 A;  4KVD A;  4QPF A;  3ASX A;  3LMD A;  2PS4 A;  3PH7 A;  3LG5 A;  3WCH A;  2OPM A;  3WEH A;  3G4F A;  3NPR A;  3P41 A;  5DGM F;  5B0I A;  5DHK A;  3SDT A;  2Z78 A;  3TFV A;  2OGD A;  4HD1 A;  5IMP A;  3SAE A;  2Q9Z A;  4LZC A;  3ZMB A;  3ICZ A;  3WSA A;  5JUZ F;  4WK5 A;  4RXD A;  5IMN A;  3VJ8 A;  4OMH A;  4MC8 A;  2AEL A;  3ICN A;  5ILD A;  1WL3 A;  3CP6 A;  3N3D A;  2E8V A;  1KIZ A;  3KRA A;  1WL2 A;  4MC3 A;  1PS1 A;  1UBV A;  2PS7 A;  4LXW A;  5IK0 A;  3WCD A;  3KRF A;  4RXC A;  3LLW A;  3ADZ A;  4LFG A;  3N5J F;  5B0J A;  3AQ0 A;  4L2X F;  4DXJ A;  3KRO B;  4N1Z F;  4KQ5 A;  3AE0 A;  3N6K F;  2Z7H A;  3QKC A;  3RBM A;  2ZCQ A;  5IN8 A;  4KFA A;  1N24 A;  5B0M A;  3WEF A;  5IL3 A;  3LDW A;  4EA2 A;  2E8T A;  3LOM A;  1N22 A;  3ICK A;  3WCC A;  3KBK A;  4LLS A;  4H5E F;  2AET A;  1V4I A;  3Q30 A;  3Q2Z A;  4E9U A;  4DHD A;  4KPD A;  3CKE A;  3ZL6 A;  3G4D A;  5HN8 A;  3WJK A;  3APZ A;  4LIX A;  3LGZ B;  3KRC A;  3WJO A;  5IK9 A;  1N1Z A;  2Z52 A;  4LUU A;  5IKH A;  5B01 A;  3P8R A;  5ERM A;  1FPS A;  4UMJ A;  3ZCD A;  3ICM A;  3S4J A;  2Q9Y A;  3OYR A;  1YHK A;  4NFJ F;  2Z4Y A;  3VJC A;  3N1W F;  3CC9 A;  5DGS F;  3ZOU A;  3N5H F;  1VG2 A;  3M02 A;  1YYU A;  2OA6 A;  3N46 F;  2E8W A;  5ILY A;  3N3L F;  4NFI F;  5ER8 A;  5ILK A;  4LFV F;  4JXN A;  1YYQ A;  1VG3 A;  4DZW A;  5DJR F;  4PVX F;  3UCA A;  3NF2 A;  3WEJ A;  4LZ3 A;  4NKF A;  3V1X A;  5JV0 F;  5EAS A;  2ZCR A;  2Z50 A;  2PS6 A;  4F6X A;  5ERO A;  1HM7 A;  3BNY A;  2Z4V A;  1UBW A;  5A0K A;  1ZW5 A;  2FTZ A;  3OAB A;  2OPN A;  2Q58 A;  1RQJ A;  3M0G A;  4MC0 A;  3OAB B;  1YJ4 A;  4XQT F;  5E8K A;  4GAX A;  3WE9 A;  3KB9 A;  2ONH A;  3WCI A;  2E91 A;  5IL8 A;  1DI1 A;  3WJN A;  3SDU A;  3WCB A;  4XQS F;  3VJA A;  5ILI A;  3BNX A;  3RYW A;  4P0W A;  3ZMC A;  3M00 A;  1N23 A;  1YHM A;  3PYB A;  1WY0 A;  3KRA B;  3SDR A;  5JV1 F;  3EGT A;  3OAC A;  3PYA A;  3PKO A;  3OAC B;  2E90 A;  3KRF B;  5IKA A;  3LZ9 A;  4JYX A;  3KRP A;  3V66 A;  1UBX A;  4GA3 A;  2PS5 A;  3Q2Q A;  5B00 A;  4DWB A;  4LZ0 A;  2Z4X A;  4LPG F;  1HXC A;  5EAU A;  2E94 A;  2E92 A;  4KKM A;  1VG7 A;  1N21 A;  1YHL A;  5CG6 A;  5CG5 A;  2DH4 A;  5HN7 A;  3VJE A;  1HXA A;  2ZCS A;  2E4O A;  2Z4W A;  5DJV F;  4KK2 A;  3P8L A;  5ILH A;  3W7F A;  3LK5 A;  3PDE A;  4FJQ A;  2H8O A;  4JZB A;  2F92 F;  3WSB A;  4DWG A;  1YYR A;  3ID0 A;  1HXG A;  3KRC B;  2Z7I A;  3LEE A;  4OKM A;  3SDV A;  3WEI A;  1WL1 A;  2E95 A;  2F8Z F;  3WCF A;  3WCA A;  4KPJ A;  4F6V A;  4NKE A;  1WMW A;  5HNA A;  3WC9 A;  1HM4 A;  1WKZ A;  3DYG A;  4DI5 A;  5DGN F;  1VG4 A;  4GP1 A;  3LSN A;  3SDQ A;  4OGU A;  4E9Z A;  2AEK A;  5A0I A;  1V4K A;  5DHI A;  3N45 F;  3N0G A;  5DIQ F;  5HN9 A;  1V4J A;  2Q80 A;  4H5C F;  1HX9 A;  4NG6 A;  4NFK F;  2J1O A;  3WCL A;  4F62 A;  2ONG A;  1UBY A;  3N0F A;  2E8X A;  3EZ3 A;  2O1O A;  2PS8 A;  1VG6 A;  1YYT A;  5KSX F;  5IK6 A;  3S9V A;  4DEM F;  2E93 A;  1DGP A;  2FOR A;  4LA6 A;  3TFP A;  4NUA A;  4ZQ8 A;  3WCM A;  3LJI A;  5ILJ A;  3M01 A;  4E1E A;  1YV5 A;  4PVY F;  4Q23 A;  2E8U A;  3IBA A;  1V4E A;  4LTV A;  3VJ9 A;  4LPH F;  5IMI A;  5AFX A;  1WL0 A;  4QXS F;  4FP4 A;  3P5P A;  5B0L A;  3NRI A;  5DZ2 A;  3VJB A;  4K10 A;  3LVS A;  2I19 A;  2ZCO A;  4P0V A;  3QQV A;  3KRP B;  1N1B A;  5IM1 A;  5AHU B;  4KVY A;  5JA0 F;  2J1P A;  2ZEV A;  3ACY A;  3LGK A;  2F94 F;  4LTZ A;  3N49 F;  5B03 A;  3N1V F;  3KRO A;  4KUX A;  3Q1O A;  3P5R A;  4RXA A;  4P0X A;  3AQC B;  3EFQ A;  4EA0 A;  3DYF A;  2QIS A;  5H9D A;  2AZL A;  3ACX A;  4LFE A;  3RYE A;  3ACW A;  2EWG A;  1YQ7 A; 
#chains in the Genus database with same CATH topology
 3WEK A;  4KWD A;  3WCE A;  4RYP A;  4LOB A;  2ZEU A;  2P1C A;  1YYS A;  1JFA A;  3WEG A;  3V1V A;  3NPK A;  3TC1 A;  5A0J A;  2Z4Z A;  2F89 F;  2F8C F;  4XQR F;  5E8L A;  4KQU A;  4OMG A;  3VJD A;  3RMG A;  1V4H A;  2J5C A;  1EZF A;  3WCG A;  5B0K A;  1RQI A;  2AZJ A;  3TS7 A;  1JFG A;  1KIY A;  5AYP A;  5ERN A;  3M9U A;  4OKZ A;  1RTR A;  3WCJ A;  5EAT A;  2F9K F;  4RXE A;  2RAH A;  2ZY1 A;  3IPI A;  4KQS A;  5IVG A;  3MZV A;  4JZX A;  4LLT A;  5AEL A;  4KVW A;  5ILZ A;  5JV2 F;  5B02 A;  2AZK A;  3TFN A;  4LA5 A;  5E8H A;  4RNQ A;  3AQB B;  4EA1 A;  4JXY A;  4H5D F;  2VF6 A;  4KVI A;  2F7M F;  1N20 A;  4GP2 A;  3MAV A;  3B7L A;  4JVJ F;  3DYH A;  5DJP F;  5DW7 A;  5I1U A;  4N9U A;  5C05 A;  4KVD A;  4QPF A;  3ASX A;  3LMD A;  2PS4 A;  3PH7 A;  3LG5 A;  3WCH A;  2OPM A;  3WEH A;  3G4F A;  3NPR A;  3P41 A;  5DGM F;  5B0I A;  5DHK A;  3SDT A;  2Z78 A;  3TFV A;  2OGD A;  4HD1 A;  5IMP A;  3SAE A;  2Q9Z A;  4LZC A;  3ZMB A;  3ICZ A;  3WSA A;  5JUZ F;  4WK5 A;  4RXD A;  5IMN A;  3VJ8 A;  4OMH A;  4MC8 A;  2AEL A;  3ICN A;  5ILD A;  1WL3 A;  3CP6 A;  3N3D A;  2E8V A;  1KIZ A;  3KRA A;  1WL2 A;  4MC3 A;  1PS1 A;  1UBV A;  2PS7 A;  4LXW A;  5IK0 A;  3WCD A;  3KRF A;  4RXC A;  3LLW A;  3ADZ A;  4LFG A;  3N5J F;  5B0J A;  3AQ0 A;  4L2X F;  4DXJ A;  3KRO B;  4N1Z F;  4KQ5 A;  3AE0 A;  3N6K F;  2Z7H A;  3QKC A;  3RBM A;  2ZCQ A;  5IN8 A;  4KFA A;  1N24 A;  5B0M A;  3WEF A;  5IL3 A;  3LDW A;  4EA2 A;  2E8T A;  3LOM A;  1N22 A;  3ICK A;  3WCC A;  3KBK A;  4LLS A;  4H5E F;  2AET A;  1V4I A;  3Q30 A;  3Q2Z A;  4E9U A;  4DHD A;  4KPD A;  3CKE A;  3ZL6 A;  3G4D A;  5HN8 A;  3WJK A;  3APZ A;  4LIX A;  3LGZ B;  3KRC A;  3WJO A;  5IK9 A;  1N1Z A;  2Z52 A;  4LUU A;  5IKH A;  5B01 A;  3P8R A;  5ERM A;  1FPS A;  4UMJ A;  3ZCD A;  3ICM A;  3S4J A;  2Q9Y A;  3OYR A;  1YHK A;  4NFJ F;  2Z4Y A;  3VJC A;  3N1W F;  3CC9 A;  5DGS F;  3ZOU A;  3N5H F;  1VG2 A;  3M02 A;  1YYU A;  2OA6 A;  3N46 F;  2E8W A;  5ILY A;  3N3L F;  4NFI F;  5ER8 A;  5ILK A;  4LFV F;  4JXN A;  1YYQ A;  1VG3 A;  4DZW A;  5DJR F;  4PVX F;  3UCA A;  3NF2 A;  3WEJ A;  4LZ3 A;  4NKF A;  3V1X A;  5JV0 F;  5EAS A;  2ZCR A;  2Z50 A;  2PS6 A;  4F6X A;  5ERO A;  1HM7 A;  3BNY A;  2Z4V A;  1UBW A;  5A0K A;  1ZW5 A;  2FTZ A;  3OAB A;  2OPN A;  2Q58 A;  1RQJ A;  3M0G A;  4MC0 A;  3OAB B;  1YJ4 A;  4XQT F;  5E8K A;  4GAX A;  3WE9 A;  3KB9 A;  2ONH A;  3WCI A;  2E91 A;  5IL8 A;  1DI1 A;  3WJN A;  3SDU A;  3WCB A;  4XQS F;  3VJA A;  5ILI A;  3BNX A;  3RYW A;  4P0W A;  3ZMC A;  3M00 A;  1N23 A;  1YHM A;  3PYB A;  1WY0 A;  3KRA B;  3SDR A;  5JV1 F;  3EGT A;  3OAC A;  3PYA A;  3PKO A;  3OAC B;  2E90 A;  3KRF B;  5IKA A;  3LZ9 A;  4JYX A;  3KRP A;  3V66 A;  1UBX A;  4GA3 A;  2PS5 A;  3Q2Q A;  5B00 A;  4DWB A;  4LZ0 A;  2Z4X A;  4LPG F;  1HXC A;  5EAU A;  2E94 A;  2E92 A;  4KKM A;  1VG7 A;  1N21 A;  1YHL A;  5CG6 A;  5CG5 A;  2DH4 A;  5HN7 A;  3VJE A;  1HXA A;  2ZCS A;  2E4O A;  2Z4W A;  5DJV F;  4KK2 A;  3P8L A;  5ILH A;  3W7F A;  3LK5 A;  3PDE A;  4FJQ A;  2H8O A;  4JZB A;  2F92 F;  3WSB A;  4DWG A;  1YYR A;  3ID0 A;  1HXG A;  3KRC B;  2Z7I A;  3LEE A;  4OKM A;  3SDV A;  3WEI A;  1WL1 A;  2E95 A;  2F8Z F;  3WCF A;  3WCA A;  4KPJ A;  4F6V A;  4NKE A;  1WMW A;  5HNA A;  3WC9 A;  1HM4 A;  1WKZ A;  3DYG A;  4DI5 A;  5DGN F;  1VG4 A;  4GP1 A;  3LSN A;  3SDQ A;  4OGU A;  4E9Z A;  2AEK A;  5A0I A;  1V4K A;  5DHI A;  3N45 F;  3N0G A;  5DIQ F;  5HN9 A;  1V4J A;  2Q80 A;  4H5C F;  1HX9 A;  4NG6 A;  4NFK F;  2J1O A;  3WCL A;  4F62 A;  2ONG A;  1UBY A;  3N0F A;  2E8X A;  3EZ3 A;  2O1O A;  2PS8 A;  1VG6 A;  1YYT A;  5KSX F;  5IK6 A;  3S9V A;  4DEM F;  2E93 A;  1DGP A;  2FOR A;  4LA6 A;  3TFP A;  4NUA A;  4ZQ8 A;  3WCM A;  3LJI A;  5ILJ A;  3M01 A;  4E1E A;  1YV5 A;  4PVY F;  4Q23 A;  2E8U A;  3IBA A;  1V4E A;  4LTV A;  3VJ9 A;  4LPH F;  5IMI A;  5AFX A;  1WL0 A;  4QXS F;  4FP4 A;  3P5P A;  5B0L A;  3NRI A;  5DZ2 A;  3VJB A;  4K10 A;  3LVS A;  2I19 A;  2ZCO A;  4P0V A;  3QQV A;  3KRP B;  1N1B A;  5IM1 A;  5AHU B;  4KVY A;  5JA0 F;  2J1P A;  2ZEV A;  3ACY A;  3LGK A;  2F94 F;  4LTZ A;  3N49 F;  5B03 A;  3N1V F;  3KRO A;  4KUX A;  3Q1O A;  3P5R A;  4RXA A;  4P0X A;  3AQC B;  3EFQ A;  4EA0 A;  3DYF A;  2QIS A;  5H9D A;  2AZL A;  3ACX A;  4LFE A;  3RYE A;  3ACW A;  2EWG A;  1YQ7 A; 
#chains in the Genus database with same CATH homology
 3WEK A;  4KWD A;  3WCE A;  4RYP A;  4LOB A;  2ZEU A;  2P1C A;  1YYS A;  1JFA A;  3WEG A;  3V1V A;  3NPK A;  3TC1 A;  5A0J A;  2Z4Z A;  2F89 F;  2F8C F;  4XQR F;  5E8L A;  4KQU A;  4OMG A;  3VJD A;  3RMG A;  1V4H A;  2J5C A;  1EZF A;  3WCG A;  5B0K A;  1RQI A;  2AZJ A;  3TS7 A;  1JFG A;  1KIY A;  5AYP A;  5ERN A;  3M9U A;  4OKZ A;  1RTR A;  3WCJ A;  5EAT A;  2F9K F;  4RXE A;  2RAH A;  2ZY1 A;  3IPI A;  4KQS A;  5IVG A;  3MZV A;  4JZX A;  4LLT A;  5AEL A;  4KVW A;  5ILZ A;  5JV2 F;  5B02 A;  2AZK A;  3TFN A;  4LA5 A;  5E8H A;  4RNQ A;  3AQB B;  4EA1 A;  4JXY A;  4H5D F;  2VF6 A;  4KVI A;  2F7M F;  1N20 A;  4GP2 A;  3MAV A;  3B7L A;  4JVJ F;  3DYH A;  5DJP F;  5DW7 A;  5I1U A;  4N9U A;  5C05 A;  4KVD A;  4QPF A;  3ASX A;  3LMD A;  2PS4 A;  3PH7 A;  3LG5 A;  3WCH A;  2OPM A;  3WEH A;  3G4F A;  3NPR A;  3P41 A;  5DGM F;  5B0I A;  5DHK A;  3SDT A;  2Z78 A;  3TFV A;  2OGD A;  4HD1 A;  5IMP A;  3SAE A;  2Q9Z A;  4LZC A;  3ZMB A;  3ICZ A;  3WSA A;  5JUZ F;  4WK5 A;  4RXD A;  5IMN A;  3VJ8 A;  4OMH A;  4MC8 A;  2AEL A;  3ICN A;  5ILD A;  1WL3 A;  3CP6 A;  3N3D A;  2E8V A;  1KIZ A;  3KRA A;  1WL2 A;  4MC3 A;  1PS1 A;  1UBV A;  2PS7 A;  4LXW A;  5IK0 A;  3WCD A;  3KRF A;  4RXC A;  3LLW A;  3ADZ A;  4LFG A;  3N5J F;  5B0J A;  3AQ0 A;  4L2X F;  4DXJ A;  3KRO B;  4N1Z F;  4KQ5 A;  3AE0 A;  3N6K F;  2Z7H A;  3QKC A;  3RBM A;  2ZCQ A;  5IN8 A;  4KFA A;  1N24 A;  5B0M A;  3WEF A;  5IL3 A;  3LDW A;  4EA2 A;  2E8T A;  3LOM A;  1N22 A;  3ICK A;  3WCC A;  3KBK A;  4LLS A;  4H5E F;  2AET A;  1V4I A;  3Q30 A;  3Q2Z A;  4E9U A;  4DHD A;  4KPD A;  3CKE A;  3ZL6 A;  3G4D A;  5HN8 A;  3WJK A;  3APZ A;  4LIX A;  3LGZ B;  3KRC A;  3WJO A;  5IK9 A;  1N1Z A;  2Z52 A;  4LUU A;  5IKH A;  5B01 A;  3P8R A;  5ERM A;  1FPS A;  4UMJ A;  3ZCD A;  3ICM A;  3S4J A;  2Q9Y A;  3OYR A;  1YHK A;  4NFJ F;  2Z4Y A;  3VJC A;  3N1W F;  3CC9 A;  5DGS F;  3ZOU A;  3N5H F;  1VG2 A;  3M02 A;  1YYU A;  2OA6 A;  3N46 F;  2E8W A;  5ILY A;  3N3L F;  4NFI F;  5ER8 A;  5ILK A;  4LFV F;  4JXN A;  1YYQ A;  1VG3 A;  4DZW A;  5DJR F;  4PVX F;  3UCA A;  3NF2 A;  3WEJ A;  4LZ3 A;  4NKF A;  3V1X A;  5JV0 F;  5EAS A;  2ZCR A;  2Z50 A;  2PS6 A;  4F6X A;  5ERO A;  1HM7 A;  3BNY A;  2Z4V A;  1UBW A;  5A0K A;  1ZW5 A;  2FTZ A;  3OAB A;  2OPN A;  2Q58 A;  1RQJ A;  3M0G A;  4MC0 A;  3OAB B;  1YJ4 A;  4XQT F;  5E8K A;  4GAX A;  3WE9 A;  3KB9 A;  2ONH A;  3WCI A;  2E91 A;  5IL8 A;  1DI1 A;  3WJN A;  3SDU A;  3WCB A;  4XQS F;  3VJA A;  5ILI A;  3BNX A;  3RYW A;  4P0W A;  3ZMC A;  3M00 A;  1N23 A;  1YHM A;  3PYB A;  1WY0 A;  3KRA B;  3SDR A;  5JV1 F;  3EGT A;  3OAC A;  3PYA A;  3PKO A;  3OAC B;  2E90 A;  3KRF B;  5IKA A;  3LZ9 A;  4JYX A;  3KRP A;  3V66 A;  1UBX A;  4GA3 A;  2PS5 A;  3Q2Q A;  5B00 A;  4DWB A;  4LZ0 A;  2Z4X A;  4LPG F;  1HXC A;  5EAU A;  2E94 A;  2E92 A;  4KKM A;  1VG7 A;  1N21 A;  1YHL A;  5CG6 A;  5CG5 A;  2DH4 A;  5HN7 A;  3VJE A;  1HXA A;  2ZCS A;  2E4O A;  2Z4W A;  5DJV F;  4KK2 A;  3P8L A;  5ILH A;  3W7F A;  3LK5 A;  3PDE A;  4FJQ A;  2H8O A;  4JZB A;  2F92 F;  3WSB A;  4DWG A;  1YYR A;  3ID0 A;  1HXG A;  3KRC B;  2Z7I A;  3LEE A;  4OKM A;  3SDV A;  3WEI A;  1WL1 A;  2E95 A;  2F8Z F;  3WCF A;  3WCA A;  4KPJ A;  4F6V A;  4NKE A;  1WMW A;  5HNA A;  3WC9 A;  1HM4 A;  1WKZ A;  3DYG A;  4DI5 A;  5DGN F;  1VG4 A;  4GP1 A;  3LSN A;  3SDQ A;  4OGU A;  4E9Z A;  2AEK A;  5A0I A;  1V4K A;  5DHI A;  3N45 F;  3N0G A;  5DIQ F;  5HN9 A;  1V4J A;  2Q80 A;  4H5C F;  1HX9 A;  4NG6 A;  4NFK F;  2J1O A;  3WCL A;  4F62 A;  2ONG A;  1UBY A;  3N0F A;  2E8X A;  3EZ3 A;  2O1O A;  2PS8 A;  1VG6 A;  1YYT A;  5KSX F;  5IK6 A;  3S9V A;  4DEM F;  2E93 A;  1DGP A;  2FOR A;  4LA6 A;  3TFP A;  4NUA A;  4ZQ8 A;  3WCM A;  3LJI A;  5ILJ A;  3M01 A;  4E1E A;  1YV5 A;  4PVY F;  4Q23 A;  2E8U A;  3IBA A;  1V4E A;  4LTV A;  3VJ9 A;  4LPH F;  5IMI A;  5AFX A;  1WL0 A;  4QXS F;  4FP4 A;  3P5P A;  5B0L A;  3NRI A;  5DZ2 A;  3VJB A;  4K10 A;  3LVS A;  2I19 A;  2ZCO A;  4P0V A;  3QQV A;  3KRP B;  1N1B A;  5IM1 A;  5AHU B;  4KVY A;  5JA0 F;  2J1P A;  2ZEV A;  3ACY A;  3LGK A;  2F94 F;  4LTZ A;  3N49 F;  5B03 A;  3N1V F;  3KRO A;  4KUX A;  3Q1O A;  3P5R A;  4RXA A;  4P0X A;  3AQC B;  3EFQ A;  4EA0 A;  3DYF A;  2QIS A;  5H9D A;  2AZL A;  3ACX A;  4LFE A;  3RYE A;  3ACW A;  2EWG A;  1YQ7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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